# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RPN7 PF10602.4 EMC90818.1 - 5.2e-25 87.8 0.0 9.1e-12 44.7 0.0 2.6 2 1 0 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.22 EMC90818.1 - 4.1e-10 39.9 0.0 7.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF3716 PF12511.3 EMC90819.1 - 3e-08 33.1 6.8 5.6e-08 32.2 4.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Chromo PF00385.19 EMC90819.1 - 0.00022 20.8 0.4 0.0085 15.7 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain C1_3 PF07649.7 EMC90819.1 - 0.85 9.7 6.0 1.6 8.8 4.2 1.5 1 0 0 1 1 1 0 C1-like domain Neur_chan_memb PF02932.11 EMC90819.1 - 2.3 8.0 6.5 0.26 11.1 1.5 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-XS PF03470.9 EMC90820.1 - 0.017 15.1 0.2 0.017 15.1 0.1 2.9 4 0 0 4 4 4 0 XS zinc finger domain TMEM154 PF15102.1 EMC90822.1 - 5.5e-05 22.9 0.1 9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family SieB PF14163.1 EMC90822.1 - 0.00025 20.6 0.2 0.00041 19.9 0.2 1.3 1 0 0 1 1 1 1 Superinfection exclusion protein B NfeD PF01957.13 EMC90822.1 - 0.012 15.7 0.1 0.03 14.4 0.1 1.7 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding UPF0104 PF03706.8 EMC90822.1 - 0.015 14.5 0.3 0.015 14.5 0.2 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) DUF443 PF04276.7 EMC90822.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Rifin_STEVOR PF02009.11 EMC90822.1 - 0.033 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Hum_adeno_E3A PF05393.6 EMC90822.1 - 0.045 13.4 0.4 0.1 12.2 0.3 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein RCR PF12273.3 EMC90822.1 - 0.094 13.2 4.8 0.19 12.2 1.6 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red CFEM PF05730.6 EMC90822.1 - 1.1 9.1 13.0 2.3 8.0 8.9 1.7 1 1 0 1 1 1 0 CFEM domain BTB PF00651.26 EMC90823.1 - 0.00012 22.0 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain AhpC-TSA_2 PF13911.1 EMC90825.1 - 3.2e-19 68.9 0.0 4.8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EMC90825.1 - 0.00037 20.1 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family NB-ARC PF00931.17 EMC90827.1 - 0.0025 16.7 0.1 0.0034 16.2 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain BTB PF00651.26 EMC90829.1 - 3.6e-08 33.3 0.0 5.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HrpJ PF07201.6 EMC90830.1 - 0.009 16.0 1.2 0.015 15.3 0.8 1.3 1 0 0 1 1 1 1 HrpJ-like domain F-box-like_2 PF13013.1 EMC90830.1 - 0.041 13.5 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 F-box-like domain MFS_1 PF07690.11 EMC90831.1 - 1.4e-23 83.2 54.5 2.2e-20 72.6 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC90831.1 - 3.4e-15 55.5 28.8 7.4e-14 51.1 20.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 EMC90831.1 - 0.18 11.4 0.6 0.31 10.6 0.4 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase S1-P1_nuclease PF02265.11 EMC90833.1 - 3.6e-67 226.6 0.5 4.1e-67 226.4 0.3 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Npa1 PF11707.3 EMC90833.1 - 0.031 13.2 0.0 4.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal Abhydrolase_3 PF07859.8 EMC90834.1 - 5.8e-37 127.3 0.0 7e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC90834.1 - 7.8e-06 25.9 0.7 1.7e-05 24.8 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC90834.1 - 1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMC90834.1 - 3.4e-05 23.3 0.0 0.091 12.1 0.0 2.2 2 0 0 2 2 2 2 Putative esterase DLH PF01738.13 EMC90834.1 - 0.00048 19.4 0.0 0.0023 17.2 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 EMC90834.1 - 0.0022 16.5 0.0 0.73 8.2 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) COesterase PF00135.23 EMC90834.1 - 0.0024 16.6 0.1 0.033 12.9 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 EMC90834.1 - 0.0058 15.8 0.0 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EMC90834.1 - 0.0069 15.8 0.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF3237 PF11578.3 EMC90835.1 - 4.5e-25 87.7 0.0 6.7e-25 87.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) PA_decarbox PF05870.6 EMC90836.1 - 4e-08 32.8 0.2 5.5e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) PQ-loop PF04193.9 EMC90837.1 - 3.3e-37 125.8 4.5 1.3e-18 66.2 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat ADH_N PF08240.7 EMC90839.1 - 3.6e-29 100.7 0.2 7.1e-29 99.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC90839.1 - 6e-22 77.5 0.1 9.1e-22 77.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC90839.1 - 6.5e-05 23.8 0.0 0.00013 22.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMC90839.1 - 0.00025 20.6 0.1 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.1 EMC90839.1 - 0.11 12.1 0.6 0.25 11.0 0.4 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Peptidase_S28 PF05577.7 EMC90840.1 - 5.9e-44 150.3 4.2 6.3e-43 146.9 2.9 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Asp PF00026.18 EMC90841.1 - 2.7e-51 174.6 2.9 3.7e-51 174.2 2.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC90841.1 - 2.4e-06 27.6 0.5 2.4e-06 27.6 0.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EMC90841.1 - 0.014 15.2 0.6 0.5 10.2 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease SKG6 PF08693.5 EMC90844.1 - 0.029 13.6 1.9 0.13 11.6 1.4 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cytochrom_B561 PF03188.11 EMC90845.1 - 1.5e-07 31.3 9.3 2.4e-07 30.6 6.5 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 EMC90845.1 - 0.0001 21.7 4.1 0.0001 21.7 2.8 2.3 1 1 1 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF2427 PF10348.4 EMC90845.1 - 0.00038 19.9 1.9 0.00038 19.9 1.3 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) XK-related PF09815.4 EMC90845.1 - 0.026 13.5 0.1 0.035 13.1 0.1 1.2 1 0 0 1 1 1 0 XK-related protein DUF418 PF04235.7 EMC90845.1 - 0.033 13.8 6.7 0.047 13.3 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) Ni_hydr_CYTB PF01292.15 EMC90845.1 - 0.037 13.4 10.4 0.9 8.8 7.2 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 TctB PF07331.6 EMC90845.1 - 0.76 9.4 8.8 1.4 8.5 6.1 1.5 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DOMON PF03351.12 EMC90846.1 - 3.5e-06 26.9 0.2 5.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Sugar_tr PF00083.19 EMC90847.1 - 5.1e-106 354.9 22.5 5.1e-106 354.9 15.6 1.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC90847.1 - 4e-20 71.8 49.7 2.7e-16 59.2 9.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily SLX9 PF15341.1 EMC90853.1 - 3.6e-26 91.9 1.6 5.2e-26 91.4 1.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF1869 PF08956.5 EMC90855.1 - 0.013 15.0 0.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) zf-B_box PF00643.19 EMC90856.1 - 0.015 15.1 4.8 0.025 14.4 3.4 1.4 1 0 0 1 1 1 0 B-box zinc finger Zn-ribbon_8 PF09723.5 EMC90856.1 - 1.1 9.2 0.1 1.1 9.2 0.0 2.9 2 1 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.7 EMC90856.1 - 2.2 8.3 8.1 3.4 7.7 0.1 2.3 1 1 0 2 2 2 0 TFIIH C1-like domain C1_1 PF00130.17 EMC90856.1 - 3 7.6 11.3 49 3.7 7.9 2.1 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MoeA_C PF03454.10 EMC90859.1 - 0.078 12.9 0.6 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) Hpt PF01627.18 EMC90860.1 - 0.12 12.3 0.1 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Hpt domain MSSP PF03940.8 EMC90861.1 - 2.4 7.5 9.4 4.1 6.8 6.5 1.4 1 0 0 1 1 1 0 Male specific sperm protein YppG PF14179.1 EMC90862.1 - 0.44 11.1 6.1 0.5 10.9 4.2 1.2 1 0 0 1 1 1 0 YppG-like protein Peroxidase_2 PF01328.12 EMC90870.1 - 1.8e-09 36.7 0.1 3.3e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 DXP_synthase_N PF13292.1 EMC90872.1 - 0.05 12.5 0.1 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF4188 PF13826.1 EMC90873.1 - 7.9e-33 113.0 0.0 1.4e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EMC90873.1 - 0.012 14.6 1.4 0.016 14.2 1.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase PapG_C PF03628.8 EMC90877.1 - 0.074 12.7 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 PapG chaperone-binding domain GDPD PF03009.12 EMC90878.1 - 1e-32 113.6 0.0 1.2e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4178 PF13785.1 EMC90882.1 - 0.064 13.2 2.2 0.31 11.0 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4178) Transformer PF06495.6 EMC90883.1 - 0.17 11.7 14.8 0.26 11.1 10.3 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein TATR PF03430.8 EMC90883.1 - 0.19 10.3 28.9 0.2 10.2 20.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Daxx PF03344.10 EMC90883.1 - 1 7.7 36.6 1.3 7.4 25.4 1.1 1 0 0 1 1 1 0 Daxx Family LicD PF04991.8 EMC90883.1 - 2.7 8.0 8.1 4.3 7.3 5.6 1.5 1 0 0 1 1 1 0 LicD family Trypan_PARP PF05887.6 EMC90883.1 - 6.5 6.5 33.3 7.2e+02 -0.1 23.1 2.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CBM_6 PF03422.10 EMC90884.1 - 0.0058 16.7 1.1 2.3 8.3 0.3 2.3 1 1 1 2 2 2 2 Carbohydrate binding module (family 6) Helicase_C PF00271.26 EMC90885.1 - 0.029 14.2 0.1 0.063 13.1 0.1 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain GBP_C PF02841.9 EMC90885.1 - 0.031 13.4 8.4 0.051 12.7 5.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DDHD PF02862.12 EMC90885.1 - 0.69 9.6 5.1 1.6 8.4 3.5 1.5 1 0 0 1 1 1 0 DDHD domain Tom37_C PF11801.3 EMC90885.1 - 0.77 9.6 6.9 18 5.1 4.2 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF1682 PF07946.9 EMC90885.1 - 1 8.1 15.0 1.7 7.4 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FemAB PF02388.11 EMC90885.1 - 1.1 7.8 7.8 1.7 7.2 5.4 1.1 1 0 0 1 1 1 0 FemAB family DUF605 PF04652.11 EMC90888.1 - 0.33 10.2 26.6 0.37 10.1 18.5 1.0 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EMC90888.1 - 6 4.9 12.7 6.7 4.8 8.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 COX7B PF05392.6 EMC90892.1 - 0.046 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB TT_ORF2a PF08197.6 EMC90892.1 - 0.059 13.1 1.0 0.14 11.9 0.7 1.6 1 0 0 1 1 1 0 pORF2a truncated protein DUF2642 PF10842.3 EMC90893.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Noelin-1 PF12308.3 EMC90899.1 - 3.2 7.5 5.7 4.2 7.2 1.7 2.2 1 1 1 2 2 2 0 Neurogenesis glycoprotein Peptidase_M35 PF02102.10 EMC90907.1 - 0.068 11.8 0.5 0.074 11.6 0.3 1.0 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Peptidase_C48 PF02902.14 EMC90913.1 - 3.2e-12 46.5 0.1 4.7e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1707 PF08044.6 EMC90913.1 - 0.31 10.8 2.4 0.49 10.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) DUF3133 PF11331.3 EMC90914.1 - 0.082 12.4 0.2 0.082 12.4 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3133) PAT1 PF09770.4 EMC90914.1 - 3.4 5.7 10.5 4.1 5.5 7.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FlxA PF14282.1 EMC90915.1 - 0.0044 16.9 12.1 0.18 11.7 0.7 3.2 1 1 1 3 3 3 2 FlxA-like protein SPX PF03105.14 EMC90915.1 - 0.0072 16.1 0.1 0.025 14.3 0.1 1.9 1 1 0 1 1 1 1 SPX domain DUF4140 PF13600.1 EMC90915.1 - 0.012 16.0 1.5 0.012 16.0 1.0 3.9 2 1 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) BBP1_C PF15272.1 EMC90915.1 - 0.014 14.9 15.0 0.37 10.3 0.8 2.9 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Reo_sigmaC PF04582.7 EMC90915.1 - 0.016 14.3 4.5 0.022 13.9 0.2 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF4315 PF14193.1 EMC90915.1 - 0.16 11.9 2.7 0.3 11.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Fib_alpha PF08702.5 EMC90915.1 - 0.32 11.1 7.4 0.46 10.5 2.0 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EMC90915.1 - 0.48 9.0 12.4 0.23 10.1 4.6 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 EMC90915.1 - 1.5 7.1 10.9 1.3 7.3 5.7 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TMF_DNA_bd PF12329.3 EMC90915.1 - 2.5 7.9 14.4 10 6.0 2.4 4.1 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 EMC90915.1 - 3 8.1 13.0 3.4 8.0 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) AAA_13 PF13166.1 EMC90915.1 - 3.2 6.0 12.6 3.4 6.0 4.6 1.9 1 1 0 1 1 1 0 AAA domain Mto2_bdg PF12808.2 EMC90915.1 - 4.6 7.4 13.0 12 6.0 0.2 3.5 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2630 PF10944.3 EMC90915.1 - 5.7 7.1 15.7 2.1 8.5 3.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2630) IncA PF04156.9 EMC90915.1 - 6.6 6.2 19.3 3.2 7.3 0.2 2.9 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EMC90915.1 - 8 6.2 21.1 0.081 12.6 3.9 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1068 PF06364.7 EMC90916.1 - 0.22 11.0 1.2 0.21 11.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) AAA_assoc PF14363.1 EMC90923.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA DUF3614 PF12267.3 EMC90925.1 - 0.019 15.2 3.3 0.038 14.2 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Tup_N PF08581.5 EMC90925.1 - 0.055 13.6 3.4 0.12 12.5 2.4 1.6 1 0 0 1 1 1 0 Tup N-terminal DUF2322 PF10084.4 EMC90927.1 - 0.027 14.1 0.6 0.074 12.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) AvrE PF11725.3 EMC90927.1 - 0.067 10.2 23.7 0.087 9.8 16.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor PT PF04886.7 EMC90930.1 - 0.66 9.3 9.6 3 7.2 0.1 2.2 2 0 0 2 2 2 0 PT repeat Antimicrobial18 PF08130.6 EMC90932.1 - 0.22 11.4 0.8 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Type A lantibiotic family NiFeSe_Hases PF00374.14 EMC90933.1 - 0.12 11.1 0.5 0.16 10.7 0.4 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RINGv PF12906.2 EMC90942.1 - 0.068 13.2 0.6 0.11 12.5 0.4 1.4 1 0 0 1 1 1 0 RING-variant domain Peptidase_C48 PF02902.14 EMC90943.1 - 5.3e-06 26.2 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ubiquitin PF00240.18 EMC90944.1 - 6.3e-09 35.1 0.0 9.7e-05 21.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.1 EMC90944.1 - 3.6e-07 30.3 0.0 5.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Keratin_B2_2 PF13885.1 EMC90949.1 - 4.5 7.0 8.5 0.74 9.5 2.4 1.9 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein Zn_clus PF00172.13 EMC90950.1 - 3.4e-05 23.6 7.7 7.2e-05 22.6 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-ISL3 PF14690.1 EMC90950.1 - 0.098 12.6 0.2 0.098 12.6 0.2 2.9 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF3119 PF11317.3 EMC90951.1 - 0.15 12.0 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3119) Peptidase_C48 PF02902.14 EMC90953.1 - 0.0098 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SUD-M PF11633.3 EMC90953.1 - 0.12 11.6 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain MIP-T3 PF10243.4 EMC90953.1 - 1.3 7.4 8.2 3 6.1 5.7 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ApoM PF11032.3 EMC90964.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 1 0 1 1 1 0 Apolipoprotein M (ApoM) GLTT PF01744.15 EMC90970.1 - 0.00011 21.5 1.5 0.0086 15.4 0.1 2.9 3 0 0 3 3 3 2 GLTT repeat (6 copies) Ribosomal_S19e PF01090.14 EMC90977.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e Peptidase_C48 PF02902.14 EMC90981.1 - 5.5e-05 22.8 0.1 5.9e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.14 EMC90987.1 - 4.7e-07 29.6 0.0 9.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain K_channel_TID PF07941.6 EMC91000.1 - 2.4 8.4 11.6 0.088 13.0 2.5 2.6 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DUF591 PF04569.9 EMC91004.1 - 0.33 11.0 4.7 0.29 11.1 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function Dynamin_N PF00350.18 EMC91006.1 - 1.2e-09 38.2 0.7 3.1e-08 33.6 0.0 2.9 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EMC91006.1 - 9.1e-06 25.6 0.0 0.013 15.4 0.0 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMC91006.1 - 0.00013 21.1 0.0 0.011 14.9 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMC91006.1 - 0.0046 17.2 0.2 0.28 11.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 EMC91006.1 - 0.012 15.4 1.3 0.12 12.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EMC91006.1 - 0.015 15.4 0.0 0.36 10.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMC91006.1 - 0.028 13.8 0.0 0.22 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain DUF2428 PF10350.4 EMC91006.1 - 0.047 12.7 0.0 0.14 11.1 0.0 1.8 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) AAA_16 PF13191.1 EMC91006.1 - 9.1 6.2 7.3 1.2 9.1 0.1 3.1 3 1 0 3 3 3 0 AAA ATPase domain JmjC PF02373.17 EMC91010.1 - 2.8e-24 85.5 0.1 6.8e-24 84.3 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EMC91010.1 - 0.029 13.8 0.0 0.098 12.1 0.0 1.9 1 0 0 1 1 1 0 Cupin domain Toxin_5 PF05294.8 EMC91019.1 - 1.1 9.4 6.9 4.5 7.5 2.4 2.3 2 0 0 2 2 2 0 Scorpion short toxin SIR2 PF02146.12 EMC91022.1 - 1.4e-25 90.0 0.0 1.9e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family NUDE_C PF04880.8 EMC91034.1 - 0.3 11.4 3.6 0.32 11.3 0.2 2.0 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF1180 PF06679.7 EMC91034.1 - 1.8 8.4 5.9 0.21 11.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) FhuF_C PF11575.3 EMC91035.1 - 0.041 13.5 0.9 0.15 11.7 0.6 2.0 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain Peptidase_C48 PF02902.14 EMC91038.1 - 5.3e-05 22.9 0.3 0.00012 21.7 0.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cas_Cas5d PF09704.5 EMC91040.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) PPPI_inhib PF14895.1 EMC91044.1 - 0.1 11.3 0.0 0.12 11.1 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor GspL_C PF12693.2 EMC91052.1 - 0.24 11.1 2.0 0.28 10.9 1.4 1.0 1 0 0 1 1 1 0 GspL periplasmic domain adh_short PF00106.20 EMC91053.1 - 1.5e-30 106.3 2.4 1.9e-30 105.9 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC91053.1 - 6.9e-30 104.5 0.9 8e-30 104.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC91053.1 - 3.7e-13 49.5 0.6 5.2e-13 49.0 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC91053.1 - 9.3e-05 21.9 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EMC91053.1 - 0.029 13.9 0.2 0.32 10.5 0.1 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1776 PF08643.5 EMC91053.1 - 0.07 12.2 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EMC91053.1 - 0.085 12.6 0.5 0.25 11.1 0.4 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans_2 PF11951.3 EMC91054.1 - 7.4e-58 195.9 0.0 1e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Far-17a_AIG1 PF04750.9 EMC91055.1 - 1.9e-64 216.5 10.1 2.2e-64 216.3 7.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Glyco_transf_8 PF01501.15 EMC91056.1 - 4.4e-09 36.0 0.0 4.4e-05 22.9 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 8 Bul1_N PF04425.7 EMC91056.1 - 0.0037 15.8 0.0 0.0057 15.2 0.0 1.2 1 0 0 1 1 1 1 Bul1 N terminus MFS_1 PF07690.11 EMC91057.1 - 1.5e-23 83.1 27.7 1.5e-23 83.1 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.14 EMC91058.1 - 2.1e-41 141.7 0.0 8.3e-25 86.9 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMC91058.1 - 1.4e-19 70.9 0.0 1.8e-18 67.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC91058.1 - 1.2e-11 44.8 0.0 5.8e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC91058.1 - 4.9e-09 36.1 0.5 4e-05 23.4 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMC91058.1 - 3.4e-07 29.4 0.3 1.8e-05 23.8 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMC91058.1 - 4.8e-07 29.7 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMC91058.1 - 1.2e-05 24.5 0.1 7.8e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EMC91058.1 - 0.00029 19.8 0.0 0.018 13.9 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMC91058.1 - 0.00066 18.2 0.1 0.1 11.0 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EMC91058.1 - 0.0063 15.4 0.0 0.98 8.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Strep_67kDa_ant PF06100.6 EMC91058.1 - 0.012 13.9 0.0 2.8 6.1 0.0 2.7 3 0 0 3 3 3 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Amino_oxidase PF01593.19 EMC91058.1 - 0.013 14.5 0.1 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EMC91058.1 - 0.016 14.2 0.1 0.028 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EMC91058.1 - 0.11 12.6 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase SprT-like PF10263.4 EMC91059.1 - 2.6e-08 33.6 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 SprT-like family BSP PF04450.7 EMC91059.1 - 0.0034 16.8 0.1 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.4 EMC91060.1 - 4.4e-07 29.6 0.0 6.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 SprT-like family DUF2464 PF10240.4 EMC91060.1 - 0.19 11.0 1.1 0.26 10.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) Sulfatase PF00884.18 EMC91063.1 - 8.6e-46 156.5 4.8 1.5e-44 152.4 0.9 2.6 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EMC91063.1 - 4.3e-09 36.1 0.4 1.1e-08 34.7 0.3 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Fumarate_red_D PF02313.12 EMC91064.1 - 0.035 13.9 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit D Herpes_UL45 PF05473.7 EMC91064.1 - 0.06 12.7 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 UL45 protein DAGAT PF03982.8 EMC91065.1 - 6.7e-90 300.7 0.0 8.6e-90 300.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Stk19 PF10494.4 EMC91066.1 - 1.5e-57 194.8 0.0 2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 PLDc_2 PF13091.1 EMC91067.1 - 1.1e-23 83.3 0.1 8.3e-14 51.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMC91067.1 - 0.027 14.2 0.3 0.5 10.2 0.1 2.8 2 0 0 2 2 2 0 Phospholipase D Active site motif Pyr_redox_3 PF13738.1 EMC91068.1 - 1.6e-21 77.3 0.0 2.8e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC91068.1 - 7.7e-14 50.7 0.0 5.4e-10 38.0 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMC91068.1 - 2.1e-13 49.9 0.0 7.3e-12 44.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMC91068.1 - 5.9e-08 32.6 0.4 3.6e-06 26.8 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC91068.1 - 1.5e-06 28.2 0.0 2.1e-05 24.4 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC91068.1 - 0.0021 17.0 0.2 0.97 8.2 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EMC91068.1 - 0.0032 16.0 0.0 0.23 9.8 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EMC91068.1 - 0.0037 17.2 0.0 0.0099 15.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC91068.1 - 0.0052 17.1 0.1 6.1 7.3 0.0 3.5 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC91068.1 - 0.06 12.2 0.0 0.23 10.3 0.0 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Mqo PF06039.10 EMC91068.1 - 0.063 11.4 0.0 1.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 EMC91068.1 - 0.094 11.5 0.0 0.65 8.7 0.0 2.0 1 1 1 2 2 2 0 FAD binding domain Thi4 PF01946.12 EMC91068.1 - 0.23 10.5 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pkinase PF00069.20 EMC91069.1 - 2.8e-64 216.7 0.0 3.4e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC91069.1 - 3e-32 111.6 0.0 3.9e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC91069.1 - 0.00023 20.2 0.0 0.00034 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC91069.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family SBP_bac_11 PF13531.1 EMC91069.1 - 0.11 12.0 0.0 1 8.9 0.0 2.2 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein IGR PF09597.5 EMC91070.1 - 3.7e-23 81.1 0.0 1.4e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 IGR protein motif DUF4140 PF13600.1 EMC91071.1 - 0.44 11.0 6.9 0.55 10.7 3.6 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATP-grasp_4 PF13535.1 EMC91072.1 - 1.8e-07 31.1 0.0 5.9e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC91072.1 - 1.2e-06 27.5 0.1 1.3e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Kinesin PF00225.18 EMC91073.1 - 2.4e-94 315.7 0.0 5.8e-94 314.5 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain DUF4051 PF13260.1 EMC91074.1 - 0.12 11.7 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DHQ_synthase PF01761.15 EMC91075.1 - 1.9e-53 181.0 0.0 2.8e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EMC91075.1 - 1.4e-11 44.2 0.0 2.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.12 EMC91076.1 - 3.7e-14 52.2 0.0 5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMC91076.1 - 2.3e-09 38.0 0.0 4.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EMC91076.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase Metallophos PF00149.23 EMC91078.1 - 2.3e-06 27.1 1.7 2.7e-05 23.6 0.4 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC91078.1 - 0.0014 18.4 0.0 0.0039 17.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNase_H PF00075.19 EMC91080.1 - 2.2e-12 47.4 0.1 9.3e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 EMC91080.1 - 0.031 14.0 0.2 6.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Glyco_transf_34 PF05637.7 EMC91082.1 - 3e-16 59.6 0.6 8.7e-13 48.3 0.4 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EMC91082.1 - 0.00032 20.0 0.2 0.0012 18.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF273 Glyco_transf_8 PF01501.15 EMC91082.1 - 0.086 12.1 0.4 0.19 11.0 0.3 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 8 Cytochrom_C1 PF02167.10 EMC91083.1 - 6.3e-83 277.7 0.0 8e-83 277.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EMC91083.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Methyltransf_11 PF08241.7 EMC91084.1 - 6e-26 90.7 0.0 1.1e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC91084.1 - 8.8e-24 83.8 0.0 1.1e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC91084.1 - 3e-18 65.8 0.0 4.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMC91084.1 - 3.1e-17 62.8 0.0 5.4e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC91084.1 - 2.9e-15 56.3 0.0 3.6e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC91084.1 - 9e-14 51.6 0.0 2e-13 50.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC91084.1 - 2.5e-13 50.5 0.0 4.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC91084.1 - 1.3e-10 41.3 0.0 2.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC91084.1 - 5.6e-10 38.8 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 EMC91084.1 - 2.5e-05 23.3 0.0 3.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.14 EMC91084.1 - 0.0005 19.6 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EMC91084.1 - 0.00053 19.4 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EMC91084.1 - 0.0013 17.9 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF3321 PF11968.3 EMC91084.1 - 0.0019 17.8 0.0 0.0059 16.2 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_16 PF10294.4 EMC91084.1 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 EMC91084.1 - 0.0046 15.3 0.0 0.0072 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EMC91084.1 - 0.0053 15.8 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CheR PF01739.13 EMC91084.1 - 0.0061 15.8 0.0 1.5 8.0 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain GCD14 PF08704.5 EMC91084.1 - 0.0078 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.1 EMC91084.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EMC91084.1 - 0.014 14.4 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_3 PF01596.12 EMC91084.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 EMC91084.1 - 0.026 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.13 EMC91084.1 - 0.029 13.5 0.0 0.14 11.3 0.0 1.9 1 1 1 2 2 2 0 O-methyltransferase UPF0020 PF01170.13 EMC91084.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.10 EMC91084.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Acetyltransf_1 PF00583.19 EMC91085.1 - 7.3e-05 22.7 0.0 0.00027 20.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC91085.1 - 0.00015 21.8 0.0 0.00039 20.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC91085.1 - 0.011 15.4 0.0 0.034 13.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EMC91085.1 - 0.019 15.1 0.0 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC91085.1 - 0.021 14.6 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_M20 PF01546.23 EMC91087.1 - 4.8e-22 78.3 0.3 7.8e-22 77.7 0.2 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMC91087.1 - 1.1e-18 66.9 0.0 3.1e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain AAA_2 PF07724.9 EMC91089.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HisG PF01634.13 EMC91093.1 - 2.3e-50 170.3 0.1 3.5e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EMC91093.1 - 1.1e-26 92.6 0.1 2e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Cellulase PF00150.13 EMC91094.1 - 3.2e-18 65.9 2.9 4.3e-18 65.5 2.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EMC91094.1 - 4.6e-06 26.9 0.0 1.2e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EMC91094.1 - 0.0002 20.4 0.0 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain FGF PF00167.13 EMC91095.1 - 0.065 13.0 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Fibroblast growth factor Sugar_tr PF00083.19 EMC91096.1 - 6.5e-71 239.2 25.7 7.7e-71 238.9 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC91096.1 - 1.8e-30 105.8 62.7 1.7e-23 82.9 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.6 EMC91096.1 - 0.015 14.7 11.5 0.016 14.6 5.4 2.6 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Fungal_trans PF04082.13 EMC91097.1 - 1.6e-21 76.3 0.0 2.6e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC91097.1 - 6.1e-06 26.0 7.9 1.2e-05 25.1 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1772 PF08592.6 EMC91098.1 - 6.4e-15 55.1 2.0 1.8e-10 40.6 0.8 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) DLH PF01738.13 EMC91099.1 - 5.9e-23 81.2 0.0 7.1e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC91099.1 - 9.8e-09 35.1 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC91099.1 - 1.6e-07 31.4 2.4 7e-06 26.0 0.2 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC91099.1 - 0.0027 16.9 0.4 0.26 10.5 0.1 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EMC91099.1 - 0.013 14.9 0.1 0.031 13.6 0.0 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EMC91099.1 - 0.057 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3141 PF11339.3 EMC91099.1 - 0.091 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DnaJ PF00226.26 EMC91100.1 - 1.4e-13 50.3 0.4 1.6e-12 46.9 0.3 2.3 1 1 0 1 1 1 1 DnaJ domain PRA1 PF03208.14 EMC91101.1 - 7.4e-41 139.0 2.0 8.4e-41 138.8 1.4 1.0 1 0 0 1 1 1 1 PRA1 family protein RhoGAP PF00620.22 EMC91102.1 - 4.4e-41 140.0 0.1 8.6e-41 139.0 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EMC91102.1 - 1e-13 51.3 0.0 2.3e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC91102.1 - 4.1e-06 27.0 0.0 1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EMC91102.1 - 0.031 14.3 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF427 PF04248.7 EMC91103.1 - 4e-38 128.9 0.1 3.4e-29 100.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF427) SBP56 PF05694.6 EMC91103.1 - 0.042 12.3 0.0 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) Pkinase PF00069.20 EMC91104.1 - 1.1e-38 132.9 0.0 1.7e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EMC91104.1 - 1.8e-35 121.5 0.0 3.7e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EMC91104.1 - 3.4e-20 72.2 0.0 1.3e-19 70.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EMC91104.1 - 5.3e-05 22.5 0.5 0.055 13.0 0.0 3.8 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.1 EMC91104.1 - 0.00067 19.1 0.2 0.032 13.6 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain Orn_Arg_deC_N PF02784.11 EMC91106.1 - 1.6e-74 250.2 0.0 2.5e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EMC91106.1 - 1.4e-29 102.1 0.0 4.8e-29 100.4 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Chitin_synth_1N PF08407.6 EMC91106.1 - 0.0053 16.4 0.5 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase N-terminal Rax2 PF12768.2 EMC91106.1 - 0.16 11.1 0.8 0.24 10.5 0.5 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity zf-C3HC4_2 PF13923.1 EMC91107.1 - 1.2e-09 38.0 9.3 1.2e-09 38.0 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC91107.1 - 2e-08 33.7 9.0 3.8e-08 32.8 4.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC91107.1 - 2.1e-08 33.8 9.4 2.1e-08 33.8 6.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC91107.1 - 2.4e-08 33.4 8.7 2.4e-08 33.4 6.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC91107.1 - 3.7e-07 29.9 9.3 3.7e-07 29.9 6.5 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMC91107.1 - 5.4e-07 29.2 8.6 5.4e-07 29.2 6.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC91107.1 - 4.6e-06 26.2 1.4 7.9e-06 25.4 0.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EMC91107.1 - 0.00026 20.7 2.6 0.00026 20.7 1.8 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein DUF1272 PF06906.6 EMC91107.1 - 0.0049 16.6 7.9 0.015 15.1 3.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) DZR PF12773.2 EMC91107.1 - 0.0096 15.7 8.1 1.3 8.9 4.9 3.0 2 1 1 3 3 3 1 Double zinc ribbon Papo_T_antigen PF02380.10 EMC91107.1 - 0.01 15.7 1.8 0.017 15.0 1.3 1.4 1 0 0 1 1 1 0 T-antigen specific domain U-box PF04564.10 EMC91107.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 U-box domain UPF0547 PF10571.4 EMC91107.1 - 0.029 14.0 0.3 0.029 14.0 0.2 3.6 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 FYDLN_acid PF09538.5 EMC91107.1 - 0.082 13.4 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-rbx1 PF12678.2 EMC91107.1 - 0.18 11.9 10.4 0.057 13.5 4.7 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger zf-Nse PF11789.3 EMC91107.1 - 0.19 11.2 2.5 0.43 10.1 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EMC91107.1 - 0.21 11.2 12.6 3.5 7.2 6.2 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain GAGA PF09237.6 EMC91107.1 - 0.4 10.3 3.3 0.55 9.8 0.6 2.3 2 0 0 2 2 2 0 GAGA factor zf-RING_3 PF14369.1 EMC91107.1 - 0.7 9.9 13.0 0.58 10.2 2.3 3.1 3 0 0 3 3 3 0 zinc-finger Ribosomal_S27e PF01667.12 EMC91107.1 - 1.5 8.4 0.0 1.5 8.4 0.0 3.2 4 0 0 4 4 4 0 Ribosomal protein S27 FYVE PF01363.16 EMC91107.1 - 1.8 8.5 10.2 31 4.5 7.1 2.9 1 1 0 1 1 1 0 FYVE zinc finger RecR PF02132.10 EMC91107.1 - 2.5 7.5 9.6 14 5.1 2.0 3.4 3 1 0 3 3 3 0 RecR protein DUF164 PF02591.10 EMC91107.1 - 3.8 7.4 10.4 11 5.8 0.1 3.5 3 1 0 3 3 3 0 Putative zinc ribbon domain HypA PF01155.14 EMC91107.1 - 6.4 6.5 9.1 19 4.9 4.1 2.8 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EMC91107.1 - 7.4 5.9 12.1 8.7 5.7 0.1 3.7 3 1 0 3 3 3 0 zinc-ribbon domain ArfGap PF01412.13 EMC91108.1 - 5.7e-38 129.2 1.1 1.1e-37 128.3 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 EMC91108.1 - 1.8e-06 27.6 0.4 3.8e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain eIF-3c_N PF05470.7 EMC91109.1 - 6.1 4.8 6.4 9.9 4.1 4.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NatB_MDM20 PF09797.4 EMC91110.1 - 7e-30 103.9 0.1 1.4e-29 102.9 0.1 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF2594 PF10769.4 EMC91110.1 - 0.01 15.8 0.9 8.1 6.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2594) Fis1_TPR_C PF14853.1 EMC91110.1 - 0.1 12.5 0.6 4.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Methyltransf_16 PF10294.4 EMC91111.1 - 9.1e-44 148.9 0.0 1.1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EMC91111.1 - 4.6e-07 29.5 0.0 6.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC91111.1 - 2e-06 28.3 0.0 2.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC91111.1 - 0.00051 19.7 0.0 0.00063 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC91111.1 - 0.00061 19.1 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EMC91111.1 - 0.0016 18.9 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain LCM PF04072.9 EMC91111.1 - 0.0036 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_2 PF00891.13 EMC91111.1 - 0.011 14.8 0.0 0.032 13.4 0.0 1.5 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_26 PF13659.1 EMC91111.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMC91111.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EMC91111.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF202 PF02656.10 EMC91113.1 - 1.5e-15 57.1 2.1 1.5e-15 57.1 1.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Peptidase_M18 PF02127.10 EMC91114.1 - 1.4e-156 521.3 0.0 4.2e-156 519.8 0.0 1.6 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Binary_toxB PF03495.9 EMC91114.1 - 0.03 12.9 1.4 0.05 12.2 1.0 1.2 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ribosomal_S28e PF01200.13 EMC91116.1 - 1e-32 111.6 3.1 1.1e-32 111.5 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e KRE9 PF05390.6 EMC91117.1 - 0.026 14.8 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 Fungal_trans_2 PF11951.3 EMC91118.1 - 8.4e-12 44.3 0.3 1.2e-11 43.8 0.0 1.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aminotran_4 PF01063.14 EMC91119.1 - 7.1e-18 64.9 0.0 9.8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Evr1_Alr PF04777.8 EMC91120.1 - 2e-28 98.1 0.1 2.6e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Med27 PF11571.3 EMC91120.1 - 0.0049 16.9 0.1 0.0068 16.5 0.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 27 Abhydrolase_1 PF00561.15 EMC91121.1 - 8.9e-16 58.1 0.1 2.8e-15 56.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC91121.1 - 1.4e-07 31.6 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family EXS PF03124.9 EMC91122.1 - 2.2e-81 273.6 10.5 2.6e-81 273.3 7.3 1.1 1 0 0 1 1 1 1 EXS family DUF4234 PF14018.1 EMC91122.1 - 0.081 12.6 7.4 0.23 11.2 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) Fe-ADH PF00465.14 EMC91123.1 - 2.8e-67 226.9 0.0 3.5e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMC91123.1 - 5.4e-05 22.6 0.0 0.0058 15.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase TMEM171 PF15471.1 EMC91125.1 - 0.015 14.0 4.0 0.2 10.4 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF2371 PF10177.4 EMC91125.1 - 0.039 13.8 0.3 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Cir_Bir_Yir PF06022.6 EMC91125.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir GMC_oxred_N PF00732.14 EMC91126.1 - 1.4e-65 221.3 0.0 1.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC91126.1 - 1.5e-31 109.5 0.0 2.9e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EMC91126.1 - 2.9e-06 26.4 0.3 4.9e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EMC91126.1 - 0.00017 20.5 0.4 0.0023 16.8 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC91126.1 - 0.00043 19.2 0.3 0.0043 15.9 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMC91126.1 - 0.0028 17.6 0.9 0.0057 16.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC91126.1 - 0.028 14.3 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC91126.1 - 0.031 13.3 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GDI PF00996.13 EMC91126.1 - 0.16 10.2 0.1 3.2 5.9 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor PARP PF00644.15 EMC91128.1 - 1.3e-06 27.9 0.0 1.4e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Zn_clus PF00172.13 EMC91129.1 - 6.3e-08 32.4 8.0 1.1e-07 31.6 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_rich_VLP PF14194.1 EMC91129.1 - 0.066 12.9 2.9 0.16 11.7 1.9 1.8 2 0 0 2 2 2 0 Cysteine-rich VLP Aminotran_3 PF00202.16 EMC91130.1 - 2.7e-107 358.5 0.0 3.8e-107 358.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EMC91130.1 - 0.0019 17.4 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMC91130.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_hydro_30 PF02055.11 EMC91131.1 - 2.8e-18 65.4 0.1 1.3e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 EMC91131.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminus MFS_1 PF07690.11 EMC91132.1 - 7.5e-26 90.6 34.8 1.2e-25 90.0 24.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC91132.1 - 5e-18 64.9 6.8 5e-18 64.9 4.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 EMC91133.1 - 6.8e-28 97.7 0.0 1e-27 97.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC91133.1 - 1.4e-12 47.2 3.6 1.7e-05 23.9 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC91133.1 - 8e-06 26.0 0.0 1.8e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC91133.1 - 0.00011 20.8 0.4 0.039 12.4 1.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMC91133.1 - 0.00016 21.6 0.0 0.00044 20.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMC91133.1 - 0.0002 20.5 0.1 0.002 17.2 0.0 2.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EMC91133.1 - 0.00048 19.0 5.0 0.0008 18.3 3.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMC91133.1 - 0.00068 19.6 2.2 0.00068 19.6 1.5 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC91133.1 - 0.0039 17.5 0.4 0.75 10.2 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC91133.1 - 0.017 14.0 1.2 4.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EMC91133.1 - 0.027 13.1 1.6 0.65 8.5 0.5 2.1 1 1 1 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EMC91133.1 - 0.042 12.6 1.2 0.066 12.0 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 EMC91133.1 - 0.043 12.6 0.0 0.71 8.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.13 EMC91133.1 - 0.061 12.9 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EMC91133.1 - 0.09 11.8 0.2 0.14 11.1 0.2 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EMC91133.1 - 0.15 11.1 2.5 0.22 10.5 1.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3500 PF12006.3 EMC91134.1 - 1.7e-87 293.3 0.0 1.9e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) AAA PF00004.24 EMC91135.1 - 3e-53 179.5 0.0 1.1e-42 145.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EMC91135.1 - 7.8e-26 89.9 0.5 1.9e-25 88.7 0.4 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EMC91135.1 - 4.1e-13 49.7 6.8 4.2e-08 33.3 0.3 4.2 3 1 1 4 4 3 2 AAA ATPase domain NACHT PF05729.7 EMC91135.1 - 6.3e-09 35.7 0.3 7e-06 25.8 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.1 EMC91135.1 - 5.2e-07 29.3 0.1 0.0027 17.4 0.0 3.4 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 EMC91135.1 - 8.9e-07 29.1 0.9 0.026 14.6 0.0 4.1 3 2 0 3 3 2 2 AAA domain RuvB_N PF05496.7 EMC91135.1 - 8.1e-06 25.0 0.1 0.012 14.6 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMC91135.1 - 1.1e-05 24.8 0.3 0.024 14.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 EMC91135.1 - 1.2e-05 26.1 0.0 0.11 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EMC91135.1 - 1.3e-05 25.1 0.0 0.0065 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EMC91135.1 - 2.3e-05 24.2 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMC91135.1 - 3.5e-05 22.9 0.0 0.071 12.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 EMC91135.1 - 0.00012 21.7 0.2 0.79 9.4 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EMC91135.1 - 0.00046 20.1 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMC91135.1 - 0.00067 19.5 0.0 0.37 10.6 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EMC91135.1 - 0.00076 19.7 0.1 0.46 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC91135.1 - 0.0012 18.2 5.2 1.9 7.8 0.1 4.3 2 2 2 4 4 4 1 AAA domain SKI PF01202.17 EMC91135.1 - 0.0025 17.6 0.0 2.7 7.8 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase Sigma54_activat PF00158.21 EMC91135.1 - 0.0026 17.2 0.0 0.17 11.3 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EMC91135.1 - 0.0032 17.5 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 EMC91135.1 - 0.0049 16.4 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EMC91135.1 - 0.0054 15.5 0.0 0.9 8.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus Vps4_C PF09336.5 EMC91135.1 - 0.0077 16.0 0.1 0.05 13.4 0.0 2.4 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain KaiC PF06745.8 EMC91135.1 - 0.0089 15.1 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.17 EMC91135.1 - 0.0093 16.1 0.0 4 7.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 EMC91135.1 - 0.011 15.4 0.0 1.9 8.0 0.0 3.1 2 1 1 3 3 3 0 Archaeal ATPase ABC_tran PF00005.22 EMC91135.1 - 0.012 15.8 0.3 5 7.4 0.0 2.9 3 0 0 3 3 2 0 ABC transporter DUF2075 PF09848.4 EMC91135.1 - 0.017 14.0 0.0 3.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EMC91135.1 - 0.018 14.2 0.1 5 6.2 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein Mg_chelatase PF01078.16 EMC91135.1 - 0.033 13.3 0.2 0.67 9.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.9 EMC91135.1 - 0.051 12.5 0.1 9.1 5.1 0.0 2.6 1 1 1 2 2 2 0 KAP family P-loop domain Cytidylate_kin2 PF13189.1 EMC91135.1 - 0.11 12.3 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_3 PF07726.6 EMC91135.1 - 0.14 11.7 0.0 6.8 6.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EMC91135.1 - 0.18 11.2 0.3 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EMC91135.1 - 0.3 10.6 1.0 6.7 6.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain Thioredoxin_7 PF13899.1 EMC91136.1 - 1.4e-13 50.6 0.0 3.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EMC91136.1 - 2e-13 49.6 0.2 5.7e-13 48.1 0.1 1.8 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EMC91136.1 - 5e-08 32.9 0.0 1.6e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 UBX domain Thioredox_DsbH PF03190.10 EMC91136.1 - 0.0039 16.9 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 EMC91136.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain UBA PF00627.26 EMC91136.1 - 0.049 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain Peptidase_M1 PF01433.15 EMC91137.1 - 6.7e-140 466.5 0.1 1.2e-139 465.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMC91137.1 - 2.3e-91 306.4 2.3 1.1e-90 304.2 0.6 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMC91137.1 - 2.1e-20 73.0 0.2 4.3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3549 PF12069.3 EMC91137.1 - 0.1 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) 4HBT_3 PF13622.1 EMC91138.1 - 2.2e-48 165.2 0.3 2.6e-48 165.0 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EMC91138.1 - 6.5e-05 22.9 0.1 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily ArfGap PF01412.13 EMC91139.1 - 4.2e-35 120.0 0.0 4.2e-35 120.0 0.0 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 EMC91139.1 - 9.4e-12 45.0 0.0 2.8e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 PH domain MFS_1 PF07690.11 EMC91141.1 - 2.5e-31 108.7 20.6 2.5e-31 108.7 14.3 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily NAD_Gly3P_dh_N PF01210.18 EMC91142.1 - 6.5e-46 155.9 0.0 3e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EMC91142.1 - 1.4e-40 138.4 0.0 2.1e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pox_VLTF3 PF04947.9 EMC91142.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Methyltransf_25 PF13649.1 EMC91143.1 - 5.2e-11 42.7 0.0 8.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC91143.1 - 0.00076 19.2 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC91143.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMC91143.1 - 0.053 13.9 0.0 0.16 12.4 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMC91143.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMC91143.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PAP1 PF08601.5 EMC91144.1 - 5.2 6.6 11.9 4.1 6.9 0.8 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 Fcf1 PF04900.7 EMC91145.1 - 2e-38 130.5 0.9 3.4e-38 129.7 0.1 1.8 2 1 0 2 2 2 1 Fcf1 MiAMP1 PF09117.5 EMC91146.1 - 0.022 15.1 0.1 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 MiAMP1 Formyl_trans_N PF00551.14 EMC91147.1 - 5.4e-39 133.6 0.0 6.5e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Pro-kuma_activ PF09286.6 EMC91148.1 - 3.3e-40 137.4 0.0 5.5e-37 126.9 0.0 2.4 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMC91148.1 - 3.6e-05 23.0 0.5 5.5e-05 22.4 0.4 1.3 1 0 0 1 1 1 1 Subtilase family RPAP3_C PF13877.1 EMC91148.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 DUF169 PF02596.10 EMC91149.1 - 0.076 12.4 0.4 0.089 12.1 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 DUF4243 PF14027.1 EMC91151.1 - 1.8e-97 326.7 0.2 2.6e-97 326.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) 2OG-FeII_Oxy_3 PF13640.1 EMC91152.1 - 0.0066 16.9 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 EMC91152.1 - 0.0091 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe dioxygenase Proteasome PF00227.21 EMC91154.1 - 9.1e-47 158.7 0.4 1.4e-32 112.5 0.0 2.6 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EMC91154.1 - 8.6e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DZR PF12773.2 EMC91155.1 - 0.085 12.6 0.5 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EMC91155.1 - 1.7 8.4 4.4 1.2 8.9 0.6 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain CTP_transf_1 PF01148.15 EMC91156.1 - 3.1e-07 30.2 2.0 3.1e-07 30.2 1.4 3.2 2 1 1 3 3 3 2 Cytidylyltransferase family DUF3543 PF12063.3 EMC91157.1 - 3.9e-75 252.1 0.6 8.3e-75 251.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EMC91157.1 - 1.4e-60 204.6 0.0 2.3e-60 203.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC91157.1 - 1.6e-38 132.2 0.0 2.8e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC91157.1 - 0.035 13.8 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pex2_Pex12 PF04757.9 EMC91158.1 - 5.4e-40 137.2 6.6 7.9e-40 136.6 4.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EMC91158.1 - 1.2e-10 41.2 9.2 1.9e-10 40.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC91158.1 - 1.6e-10 40.6 10.4 2.6e-10 39.9 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC91158.1 - 2e-09 36.9 8.3 3.2e-09 36.2 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC91158.1 - 1.2e-08 34.5 7.0 1.8e-08 33.8 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC91158.1 - 9.8e-08 31.6 6.6 1.6e-07 30.9 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC91158.1 - 2.9e-05 23.8 9.3 4.9e-05 23.1 6.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC91158.1 - 3.4e-05 23.4 1.5 3.4e-05 23.4 1.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMC91158.1 - 7.2e-05 22.8 9.0 0.00023 21.2 6.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EMC91158.1 - 0.00033 20.3 2.9 0.00064 19.4 2.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EMC91158.1 - 0.0024 17.3 1.6 0.0053 16.2 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EMC91158.1 - 0.018 14.8 7.0 0.034 13.9 4.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMC91158.1 - 0.04 13.4 8.3 0.073 12.6 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EMC91158.1 - 3.6 7.4 6.8 8.1 6.3 4.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 EMC91158.1 - 4.2 7.3 8.4 16 5.4 5.8 1.9 1 1 0 1 1 1 0 IBR domain HAD PF12710.2 EMC91159.1 - 9.7e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fer2_3 PF13085.1 EMC91160.1 - 1e-31 109.0 0.0 1.6e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EMC91160.1 - 1.3e-09 38.2 6.6 1.3e-09 38.2 4.6 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMC91160.1 - 6.7e-09 35.6 4.8 6.7e-09 35.6 3.3 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMC91160.1 - 0.00052 20.2 4.0 0.026 14.7 0.4 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMC91160.1 - 0.00093 19.5 2.1 0.00093 19.5 1.5 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMC91160.1 - 0.001 18.7 4.7 0.001 18.7 3.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EMC91160.1 - 0.0074 16.0 0.3 0.0074 16.0 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EMC91160.1 - 1 9.9 5.1 0.83 10.2 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_7 PF12838.2 EMC91160.1 - 1.9 8.9 14.5 0.067 13.5 4.8 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain AA_permease PF00324.16 EMC91161.1 - 9.4e-110 367.1 38.8 1.1e-109 366.9 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMC91161.1 - 2.1e-35 122.1 39.1 2.8e-35 121.7 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.7 EMC91161.1 - 0.05 13.6 0.2 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) TPR_11 PF13414.1 EMC91162.1 - 4e-12 45.6 6.5 8.3e-10 38.1 2.6 2.5 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EMC91162.1 - 2.1e-07 30.2 4.9 0.00029 20.3 0.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat F-box-like PF12937.2 EMC91162.1 - 3.9e-07 29.7 0.8 9.6e-07 28.4 0.6 1.7 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.12 EMC91162.1 - 7.2e-06 25.5 11.2 0.0046 16.7 0.2 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat F-box PF00646.28 EMC91162.1 - 0.00012 21.6 1.4 0.0005 19.6 0.1 2.6 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EMC91162.1 - 0.0005 19.7 0.1 0.0005 19.7 0.0 4.5 3 1 2 5 5 5 1 Leucine rich repeat TPR_12 PF13424.1 EMC91162.1 - 0.00062 19.6 4.5 0.1 12.5 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat LRR_4 PF12799.2 EMC91162.1 - 0.0013 18.3 11.7 0.0039 16.7 0.0 5.0 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) TPR_9 PF13371.1 EMC91162.1 - 0.0013 18.5 2.8 0.0042 16.9 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC91162.1 - 0.017 15.8 8.0 0.77 10.5 0.4 2.6 2 1 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC91162.1 - 0.036 14.7 8.0 2.4 9.0 0.3 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC91162.1 - 0.078 13.3 2.9 2 8.7 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC91162.1 - 0.089 12.9 1.2 0.2 11.8 0.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3760 PF12586.3 EMC91162.1 - 0.1 12.4 0.9 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) MFS_1 PF07690.11 EMC91163.1 - 2e-16 59.7 30.8 2e-16 59.7 21.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.27 EMC91165.1 - 7.5e-27 92.2 11.9 9.3e-09 34.8 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EMC91165.1 - 0.0034 15.5 1.8 0.034 12.2 0.4 3.0 3 1 0 3 3 3 1 Nucleoporin Nup120/160 RhoGAP PF00620.22 EMC91166.1 - 1.8e-16 60.1 0.0 4.1e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EMC91166.1 - 3.2e-15 56.0 0.0 7.6e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EMC91166.1 - 1.7e-10 40.4 0.0 3.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Sipho_Gp157 PF05565.6 EMC91166.1 - 0.05 13.1 0.4 5.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Siphovirus Gp157 YTH PF04146.10 EMC91167.1 - 1.2e-54 183.7 0.0 1.6e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 EMC91167.1 - 4.2e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC91167.1 - 1.5e-05 24.5 0.0 4e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3694 PF12473.3 EMC91167.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Kinesin protein RRM_5 PF13893.1 EMC91167.1 - 0.14 11.9 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.22 EMC91169.1 - 3.7e-40 137.8 0.0 1.1e-39 136.3 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EMC91169.1 - 9.2e-25 86.8 0.0 2.2e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pyr_redox_2 PF07992.9 EMC91170.1 - 7.9e-31 107.4 0.0 1.2e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC91170.1 - 1.3e-13 51.1 0.0 1.8e-10 41.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC91170.1 - 1.6e-05 23.9 0.0 0.46 9.2 0.0 3.7 2 2 1 4 4 4 2 FAD binding domain Pyr_redox_3 PF13738.1 EMC91170.1 - 2.4e-05 24.4 0.0 1.2 9.1 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trehalase_Ca-bi PF07492.6 EMC91170.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain But2 PF09792.4 EMC91171.1 - 4.6e-40 136.6 1.8 9e-40 135.7 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_17 PF00332.13 EMC91171.1 - 0.0028 16.7 2.0 0.0073 15.3 1.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 zf-CSL PF05207.8 EMC91172.1 - 4.4e-18 64.5 0.5 6.5e-18 63.9 0.4 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EMC91172.1 - 1.8e-15 56.4 0.3 2.6e-15 55.8 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Suf PF05843.9 EMC91173.1 - 0.00017 21.4 2.8 0.0047 16.7 0.1 2.6 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EMC91173.1 - 0.0016 18.9 7.9 9.9 7.1 0.0 6.7 6 3 2 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC91173.1 - 0.01 16.4 7.1 0.07 13.8 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2458 PF10454.4 EMC91173.1 - 0.022 14.6 1.6 0.06 13.2 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) TPR_19 PF14559.1 EMC91173.1 - 0.048 14.0 0.1 1.8 8.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EMC91174.1 - 1.4e-88 297.5 27.1 1.6e-88 297.2 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC91174.1 - 6.9e-30 103.9 36.7 1e-28 100.1 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMC91174.1 - 9.4e-08 30.6 4.2 9.4e-08 30.6 2.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 EMC91177.1 - 1.9e-24 84.6 5.3 3.2e-10 39.4 0.4 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EMC91177.1 - 0.008 14.3 0.3 0.016 13.4 0.2 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC91177.1 - 0.012 14.4 0.1 3.5 6.2 0.0 2.9 1 1 1 3 3 3 0 Nup133 N terminal like Cupin_2 PF07883.6 EMC91179.1 - 1.5e-06 27.6 0.1 0.016 14.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EMC91179.1 - 0.00018 20.9 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMC91179.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.9 EMC91179.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Acetyltransf_1 PF00583.19 EMC91180.1 - 0.00027 20.9 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC91180.1 - 0.0011 19.0 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC91180.1 - 0.0015 18.6 0.0 0.0035 17.4 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC91180.1 - 0.1 12.4 0.1 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GCD14 PF08704.5 EMC91181.1 - 2.5e-60 204.0 0.0 6.1e-60 202.7 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EMC91181.1 - 0.0027 17.7 0.0 0.0065 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain GST_N_3 PF13417.1 EMC91182.1 - 4.5e-12 46.0 0.0 9.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC91182.1 - 2.2e-08 33.9 0.0 4.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC91182.1 - 9.1e-06 25.4 0.1 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC91182.1 - 8.7e-05 22.9 0.1 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC91182.1 - 0.00094 19.1 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hexapep PF00132.19 EMC91184.1 - 2e-09 36.4 8.0 8e-06 25.1 1.5 3.1 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMC91184.1 - 0.00033 20.7 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EMC91184.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.1 EMC91184.1 - 1.3 8.6 13.1 0.82 9.2 2.5 3.4 2 2 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase WD40 PF00400.27 EMC91185.1 - 2.3e-24 84.3 12.1 3.6e-06 26.6 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 EMC91185.1 - 0.0036 16.5 0.0 0.011 15.0 0.0 1.7 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Gmad1 PF10647.4 EMC91185.1 - 0.065 12.6 1.0 5.8 6.2 0.3 3.0 2 2 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain RRM_1 PF00076.17 EMC91186.1 - 9.3e-13 47.6 0.0 4.9e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC91186.1 - 7.2e-11 41.7 0.0 9.8e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC91186.1 - 1.2e-09 37.9 0.0 3.2e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 EMC91186.1 - 0.014 14.9 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Limkain-b1 PF11608.3 EMC91186.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 Limkain b1 Autophagy_act_C PF03987.10 EMC91187.1 - 1.9e-09 37.5 0.1 3.3e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain HPP PF04982.8 EMC91187.1 - 0.042 13.6 3.3 5.5 6.8 1.2 2.2 1 1 0 2 2 2 0 HPP family SKG6 PF08693.5 EMC91190.1 - 9.8e-05 21.5 0.4 0.0002 20.5 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EMC91190.1 - 0.00069 19.0 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 EMC91190.1 - 0.037 13.5 0.1 0.085 12.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 EMC91190.1 - 0.046 11.9 0.1 0.068 11.4 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EMC91190.1 - 0.059 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMC91190.1 - 0.065 13.4 3.7 0.12 12.5 1.8 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DcuC PF03606.10 EMC91190.1 - 0.12 10.5 0.6 0.18 10.0 0.4 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier PNPOx_C PF10590.4 EMC91191.1 - 6.4e-22 76.7 4.4 7.9e-22 76.4 1.9 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EMC91191.1 - 1.8e-16 59.9 0.0 3.1e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EMC91191.1 - 0.0011 19.2 0.2 0.0019 18.4 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Zn_clus PF00172.13 EMC91193.1 - 4.2e-10 39.3 7.7 7.5e-10 38.5 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMC91193.1 - 1.3e-07 30.5 2.3 1.4e-07 30.5 0.2 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain TPR_12 PF13424.1 EMC91193.1 - 0.003 17.4 0.3 0.0081 16.0 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat MgsA_C PF12002.3 EMC91194.1 - 4e-57 192.5 0.2 6.4e-57 191.8 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EMC91194.1 - 9.5e-15 54.9 0.0 2.6e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMC91194.1 - 3.6e-11 42.5 0.0 7e-11 41.6 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMC91194.1 - 1.8e-05 24.4 0.0 4.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EMC91194.1 - 2.7e-05 23.7 0.0 0.00062 19.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EMC91194.1 - 3.6e-05 23.4 0.2 0.002 17.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMC91194.1 - 8.7e-05 22.1 0.0 0.0003 20.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC91194.1 - 0.0001 22.4 0.2 0.00047 20.2 0.1 2.0 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMC91194.1 - 0.00011 21.4 0.1 0.19 10.8 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMC91194.1 - 0.00055 20.7 0.0 0.0016 19.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 EMC91194.1 - 0.00098 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EMC91194.1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMC91194.1 - 0.0032 17.4 0.2 0.0059 16.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC91194.1 - 0.0036 17.3 0.4 0.19 11.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 EMC91194.1 - 0.011 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 EMC91194.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SKI PF01202.17 EMC91194.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase TIP49 PF06068.8 EMC91194.1 - 0.023 13.4 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EMC91194.1 - 0.023 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EMC91194.1 - 0.024 14.1 0.2 0.084 12.4 0.1 1.9 2 1 0 2 2 1 0 AAA domain ResIII PF04851.10 EMC91194.1 - 0.047 13.5 0.3 4.4 7.0 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EMC91194.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein FKBP_C PF00254.23 EMC91195.1 - 5.1e-25 87.3 0.1 6e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.14 EMC91196.1 - 4.5e-12 46.0 0.5 1.2e-11 44.7 0.3 1.7 1 1 0 1 1 1 1 PHP domain Pkinase PF00069.20 EMC91197.1 - 3.2e-74 249.3 0.0 5.7e-74 248.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC91197.1 - 2.8e-35 121.6 0.0 3.7e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMC91197.1 - 4e-15 55.6 0.2 7.5e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EMC91197.1 - 3.1e-11 42.7 0.0 4.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EMC91197.1 - 0.0047 15.7 0.0 0.0069 15.2 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EMC91197.1 - 0.04 12.9 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC91197.1 - 0.079 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Acyl-CoA_dh_N PF02771.11 EMC91198.1 - 9.1e-18 64.8 0.1 2.5e-17 63.4 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMC91198.1 - 1.4e-05 24.4 0.0 5.2e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain p450 PF00067.17 EMC91199.1 - 6.1e-73 245.9 0.0 7.4e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.16 EMC91200.1 - 3.7e-12 45.9 0.0 6.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase CMD PF02627.15 EMC91201.1 - 5.1e-10 39.0 0.2 1.1e-09 37.9 0.2 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family IcmF-related PF06761.7 EMC91201.1 - 0.027 13.7 0.1 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Intracellular multiplication and human macrophage-killing Lysozyme_like PF13702.1 EMC91201.1 - 0.057 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Lysozyme-like PAPA-1 PF04795.7 EMC91204.1 - 4e-07 30.6 10.8 9e-07 29.5 5.4 2.8 2 0 0 2 2 2 1 PAPA-1-like conserved region SDA1 PF05285.7 EMC91204.1 - 0.25 10.6 32.1 0.59 9.3 4.3 2.1 2 0 0 2 2 2 0 SDA1 Pex14_N PF04695.8 EMC91205.1 - 2.5e-15 56.7 0.1 2.5e-15 56.7 0.1 3.3 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NikR_C PF08753.6 EMC91205.1 - 2.8 7.8 4.1 7.8 6.4 0.1 2.5 3 0 0 3 3 3 0 NikR C terminal nickel binding domain UPF0086 PF01868.11 EMC91206.1 - 1.1e-24 85.8 0.2 1.9e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 M16C_assoc PF08367.6 EMC91208.1 - 1.6e-57 194.2 0.0 1.4e-56 191.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EMC91208.1 - 1.4e-34 119.3 0.0 5.5e-21 75.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMC91208.1 - 2.1e-08 34.0 0.0 7.8e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 EMC91209.1 - 7e-80 268.3 57.6 9.9e-80 267.9 39.9 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Myosin_tail_1 PF01576.14 EMC91209.1 - 0.14 9.8 64.3 1.2 6.7 23.0 2.1 1 1 1 2 2 2 0 Myosin tail NOA36 PF06524.7 EMC91209.1 - 1.3 8.1 7.6 4.2 6.5 5.3 1.9 1 0 0 1 1 1 0 NOA36 protein IncA PF04156.9 EMC91209.1 - 2.4 7.7 60.4 0.26 10.8 10.3 3.7 1 1 1 3 3 3 0 IncA protein GHMP_kinases_C PF08544.8 EMC91209.1 - 2.5 8.3 5.5 3.5 7.9 0.1 3.3 3 1 0 3 3 3 0 GHMP kinases C terminal Abhydrolase_5 PF12695.2 EMC91210.1 - 7.6e-15 54.9 0.1 1e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC91210.1 - 2e-07 31.1 0.2 2.9e-05 24.0 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EMC91210.1 - 1.5e-05 24.3 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EMC91210.1 - 8.3e-05 22.2 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC91210.1 - 0.00016 20.9 0.0 0.13 11.5 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 EMC91210.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1749 PF08538.5 EMC91210.1 - 0.039 12.8 0.0 0.084 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) VirJ PF06057.6 EMC91210.1 - 0.04 13.6 0.0 0.092 12.5 0.0 1.5 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) LCAT PF02450.10 EMC91210.1 - 0.056 12.4 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DEAD PF00270.24 EMC91211.1 - 2e-46 157.5 0.0 3.4e-45 153.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC91211.1 - 4.4e-28 96.9 0.1 8.6e-28 96.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC91211.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EMC91211.1 - 0.037 12.4 0.0 0.081 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EMC91211.1 - 0.065 12.2 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Mnd1 PF03962.10 EMC91213.1 - 1.1e-44 152.3 2.0 1.4e-44 152.0 1.4 1.0 1 0 0 1 1 1 1 Mnd1 family Macoilin PF09726.4 EMC91213.1 - 0.00084 17.7 2.3 0.001 17.4 1.6 1.0 1 0 0 1 1 1 1 Transmembrane protein UBA_e1_C PF09358.5 EMC91213.1 - 0.11 12.7 0.3 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Fib_alpha PF08702.5 EMC91213.1 - 1.5 8.9 3.9 14 5.8 0.6 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AMP-binding PF00501.23 EMC91214.1 - 2.9e-65 220.2 0.0 3.7e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC91214.1 - 6.8e-10 39.7 0.0 1.4e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EMC91215.1 - 0.00017 21.6 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC91215.1 - 0.00084 18.6 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EMC91215.1 - 0.0027 17.9 0.1 0.0073 16.6 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Pepsin-I3 PF06394.8 EMC91215.1 - 0.03 13.9 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain hDGE_amylase PF14701.1 EMC91216.1 - 5.1e-173 575.8 0.0 6.6e-173 575.4 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EMC91216.1 - 2.3e-110 368.8 0.0 4.1e-110 367.9 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EMC91216.1 - 1.5e-84 283.2 0.0 2.1e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EMC91216.1 - 2.8e-27 94.3 0.1 7.8e-27 92.9 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EMC91216.1 - 1.1e-05 24.9 0.2 0.0074 15.7 0.1 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF3367 PF11847.3 EMC91217.1 - 0.088 10.7 0.0 0.16 9.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Peptidase_M16_C PF05193.16 EMC91218.1 - 1.8e-28 99.4 0.0 1.7e-21 76.7 0.0 3.2 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMC91218.1 - 1.2e-06 28.3 0.1 3.9e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF4590 PF15257.1 EMC91218.1 - 0.16 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) Ribosomal_S13 PF00416.17 EMC91220.1 - 3.2e-23 82.2 0.1 4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 EMC91221.1 - 2.8e-47 160.7 0.9 3.5e-47 160.4 0.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short PF00106.20 EMC91222.1 - 1.2e-21 77.3 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC91222.1 - 6.5e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC91222.1 - 2.1e-05 24.4 0.0 2.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMC91222.1 - 0.0015 18.5 0.1 0.0034 17.4 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMC91222.1 - 0.012 14.7 0.0 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EMC91222.1 - 0.021 14.1 0.1 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Polysacc_deac_1 PF01522.16 EMC91222.1 - 0.066 12.8 0.0 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide deacetylase DAP3 PF10236.4 EMC91223.1 - 2e-85 286.4 0.0 2.6e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.1 EMC91223.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMC91223.1 - 0.066 13.2 0.2 0.25 11.3 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 EMC91223.1 - 0.17 11.5 0.2 4 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 LRR_4 PF12799.2 EMC91224.1 - 2.2e-11 43.0 9.1 1.8e-07 30.6 0.7 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC91224.1 - 1.3e-09 37.6 2.7 1.3e-09 37.6 1.9 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EMC91224.1 - 1.4e-06 27.5 8.2 0.055 13.5 0.1 4.3 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC91224.1 - 0.00053 19.7 9.2 0.6 10.5 0.4 4.7 4 0 0 4 4 4 2 Leucine rich repeat DUF2368 PF10166.4 EMC91224.1 - 0.15 11.6 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) LRR_6 PF13516.1 EMC91224.1 - 0.36 11.0 3.4 22 5.5 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich repeat DnaJ PF00226.26 EMC91225.1 - 6e-20 70.7 4.7 1.3e-19 69.6 2.2 2.0 2 0 0 2 2 2 1 DnaJ domain Gly-zipper_OmpA PF13436.1 EMC91225.1 - 0.027 14.1 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EMC91225.1 - 0.32 11.1 5.0 0.66 10.1 3.5 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide TPR_11 PF13414.1 EMC91226.1 - 1.2e-07 31.2 0.6 2.8e-06 26.8 0.1 3.0 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.1 EMC91226.1 - 6.3e-07 29.6 1.6 3.6e-06 27.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC91226.1 - 4.6e-05 22.8 0.4 0.00019 20.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC91226.1 - 0.0002 21.9 3.7 0.036 14.7 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC91226.1 - 0.00021 21.2 0.1 0.011 15.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC91226.1 - 0.0005 19.8 0.3 0.0014 18.4 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC91226.1 - 0.00072 19.9 3.8 0.013 16.0 0.3 3.8 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMC91226.1 - 0.00072 19.6 0.3 0.013 15.6 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC91226.1 - 0.001 18.7 1.2 0.0086 15.9 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC91226.1 - 0.0013 18.8 0.0 0.0038 17.3 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMC91226.1 - 0.0017 17.8 1.0 0.0062 16.0 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC91226.1 - 0.0077 16.1 0.4 0.043 13.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC91226.1 - 0.0082 15.8 0.2 0.044 13.5 0.1 2.3 2 0 0 2 2 1 1 Tetratricopeptide repeat ChAPs PF09295.5 EMC91226.1 - 0.03 13.1 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EMC91226.1 - 0.044 14.2 2.9 1.1 9.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Adaptin_N PF01602.15 EMC91227.1 - 1.5e-81 274.3 0.0 2.7e-81 273.4 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMC91227.1 - 0.0086 15.9 0.5 4.5 7.0 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMC91227.1 - 0.047 13.7 0.4 12 6.3 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Consortin_C PF15281.1 EMC91227.1 - 0.2 11.1 0.3 12 5.4 0.1 2.4 2 0 0 2 2 2 0 Consortin C-terminus Fungal_trans_2 PF11951.3 EMC91229.1 - 4.6e-78 262.4 0.0 7.1e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC91229.1 - 1.5e-06 28.0 9.0 3.2e-06 26.9 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 EMC91231.1 - 8.4e-09 35.1 0.2 1.6e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC91231.1 - 6.1e-07 29.5 0.3 1.6e-06 28.1 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EMC91231.1 - 5.6e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC91231.1 - 0.053 13.7 0.1 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain WBS_methylT PF12589.3 EMC91232.1 - 8.2e-15 55.0 6.0 1.6e-14 54.1 4.1 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EMC91232.1 - 2e-11 44.2 0.0 3.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC91232.1 - 3.5e-08 33.7 0.0 8e-08 32.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC91232.1 - 7.3e-06 25.6 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC91232.1 - 1.1e-05 25.8 0.0 3.2e-05 24.3 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC91232.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC91232.1 - 3.1e-05 23.6 0.0 6.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EMC91232.1 - 8.7e-05 23.0 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC91232.1 - 0.0027 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMC91232.1 - 0.0076 15.3 0.0 0.027 13.5 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EMC91232.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EMC91232.1 - 0.024 14.3 0.1 0.052 13.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EMC91232.1 - 0.075 12.4 0.8 4 6.7 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase small domain DUF3724 PF12521.3 EMC91232.1 - 0.11 12.2 0.1 0.28 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) MetW PF07021.7 EMC91232.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Erv26 PF04148.8 EMC91233.1 - 5.1e-89 297.2 0.1 5.8e-89 297.0 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3329 PF11808.3 EMC91233.1 - 8.9 6.4 9.0 12 6.0 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3329) Perm-CXXC PF15629.1 EMC91234.1 - 0.12 12.3 22.1 19 5.3 0.0 8.1 8 0 0 8 8 8 0 Permuted single zf-CXXC unit DUF4407 PF14362.1 EMC91234.1 - 4 6.3 11.9 0.27 10.1 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4407) DUF4418 PF14387.1 EMC91234.1 - 6.6 6.4 12.3 2.2 8.0 0.1 5.3 5 2 1 6 6 6 0 Domain of unknown function (DUF4418) Peptidase_C48 PF02902.14 EMC91237.1 - 4e-16 59.2 0.2 2.9e-15 56.4 0.1 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Iso_dh PF00180.15 EMC91238.1 - 1.8e-85 286.9 0.0 2.2e-85 286.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DSBA PF01323.15 EMC91239.1 - 2.8e-14 53.1 0.0 3.2e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain UCH PF00443.24 EMC91240.1 - 1.8e-26 92.8 0.0 2.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC91240.1 - 4.4e-09 36.3 0.0 7.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMC91240.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AAA_16 PF13191.1 EMC91241.1 - 0.001 19.1 0.7 0.0086 16.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EMC91241.1 - 0.0075 15.9 1.1 0.12 11.9 0.0 3.2 3 1 1 4 4 4 1 NACHT domain AAA_25 PF13481.1 EMC91241.1 - 0.016 14.6 0.1 0.071 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EMC91241.1 - 0.074 13.1 1.1 2.1 8.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain TPR_14 PF13428.1 EMC91242.1 - 6.6e-06 26.3 6.0 2.2 9.1 0.0 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC91242.1 - 0.0001 21.8 2.8 0.018 14.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC91242.1 - 0.00011 22.7 0.3 1.3 9.7 0.0 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC91242.1 - 0.00057 20.1 0.2 5.6 7.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMC91242.1 - 0.00064 19.3 0.2 0.66 9.6 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EMC91242.1 - 0.027 14.3 5.6 8.2 6.6 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC91242.1 - 0.27 11.2 5.9 0.37 10.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC91242.1 - 0.44 10.2 2.5 8.2 6.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 EMC91245.1 - 7.1e-48 162.8 0.0 9.3e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.6 EMC91245.1 - 0.00098 18.4 0.7 0.068 12.5 0.3 2.4 2 0 0 2 2 2 2 Poliovirus 3A protein like IF-2B PF01008.12 EMC91246.1 - 8.1e-76 254.6 0.4 1e-75 254.3 0.3 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family AIG2_2 PF13772.1 EMC91247.1 - 3.9e-06 26.8 0.5 4e-05 23.6 0.4 2.1 1 1 0 1 1 1 1 AIG2-like family OTT_1508_deam PF14441.1 EMC91249.1 - 1.5e-08 34.5 0.1 3.4e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase EF-hand_4 PF12763.2 EMC91250.1 - 2.1e-25 88.4 0.0 1.3e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EMC91250.1 - 3.6e-10 39.7 166.8 2.3e-06 27.5 17.1 8.5 5 2 3 8 8 8 5 Domain of unknown function (DUF1720) WH2 PF02205.15 EMC91250.1 - 5.2e-06 25.8 0.6 5.2e-06 25.8 0.4 3.1 3 0 0 3 3 3 1 WH2 motif EF-hand_7 PF13499.1 EMC91250.1 - 0.00025 21.0 0.0 0.053 13.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC91250.1 - 0.00065 18.8 0.0 0.13 11.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC91250.1 - 0.02 14.7 0.1 8.5 6.5 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain HCNGP PF07818.8 EMC91251.1 - 3.6e-16 58.9 0.0 6.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.21 EMC91252.1 - 4.4e-28 97.8 0.0 5.1e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit eIF3_subunit PF08597.5 EMC91253.1 - 3.2e-58 197.1 16.9 3.6e-58 197.0 11.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit p450 PF00067.17 EMC91253.1 - 0.054 12.0 0.0 0.054 12.0 0.0 1.6 2 0 0 2 2 2 0 Cytochrome P450 Drc1-Sld2 PF11719.3 EMC91253.1 - 0.056 12.5 13.9 0.096 11.7 9.7 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Rrn6 PF10214.4 EMC91253.1 - 0.12 10.4 0.4 0.15 10.1 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TIMELESS PF04821.9 EMC91253.1 - 0.23 10.6 0.1 0.23 10.6 0.1 2.5 2 1 1 3 3 3 0 Timeless protein Atrophin-1 PF03154.10 EMC91253.1 - 1.4 7.0 18.4 0.065 11.3 8.9 1.6 2 0 0 2 2 2 0 Atrophin-1 family Clathrin PF00637.15 EMC91254.1 - 2.5e-203 665.8 26.4 5.5e-33 113.5 1.7 7.6 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EMC91254.1 - 1.4e-31 108.1 2.3 4.7e-31 106.4 1.0 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EMC91254.1 - 2.1e-26 90.3 0.9 1.9e-06 27.8 0.0 7.5 7 0 0 7 7 7 6 Clathrin propeller repeat Vps39_1 PF10366.4 EMC91254.1 - 1.2e-05 25.3 4.2 1.9 8.5 0.0 5.9 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.1 EMC91254.1 - 0.00042 19.8 7.8 13 5.8 0.0 7.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EMC91254.1 - 0.0019 17.1 3.5 0.077 11.7 0.1 4.1 4 0 0 4 4 4 1 Coatomer WD associated region Clathrin-link PF09268.5 EMC91254.1 - 0.01 14.8 0.2 0.026 13.5 0.1 1.8 1 0 0 1 1 1 0 Clathrin, heavy-chain linker TPR_14 PF13428.1 EMC91254.1 - 0.21 12.3 27.6 6.7 7.6 0.0 11.3 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC91254.1 - 0.71 9.9 0.0 0.71 9.9 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC91254.1 - 2.3 8.6 8.1 16 6.0 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC91254.1 - 5.5 6.7 9.3 3.3 7.4 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat HhH-GPD PF00730.20 EMC91255.1 - 6.9e-08 32.7 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein WD40 PF00400.27 EMC91256.1 - 3.1e-71 232.9 21.8 3e-10 39.5 0.1 13.0 13 2 0 13 13 13 10 WD domain, G-beta repeat Utp13 PF08625.6 EMC91256.1 - 8e-40 135.7 0.6 1.3e-39 135.1 0.4 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EMC91256.1 - 9.1e-11 40.5 10.3 0.021 12.9 0.0 6.4 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC91256.1 - 0.00012 20.9 1.3 0.94 8.1 0.0 5.1 2 2 3 5 5 5 2 Nup133 N terminal like Proteasome PF00227.21 EMC91257.1 - 1.9e-36 125.1 0.0 2.2e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit cobW PF02492.14 EMC91259.1 - 2.5e-33 115.0 0.1 3.5e-33 114.5 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EMC91259.1 - 0.00011 21.9 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EMC91259.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 EMC91259.1 - 0.00051 19.6 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EMC91259.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC91259.1 - 0.0021 18.1 0.2 0.011 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EMC91259.1 - 0.0026 16.7 0.0 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EMC91259.1 - 0.0029 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain CbiA PF01656.18 EMC91259.1 - 0.0039 16.6 0.1 0.03 13.7 0.1 2.3 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EMC91259.1 - 0.039 14.2 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMC91259.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMC91259.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 EMC91259.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain BRX PF08381.6 EMC91259.1 - 0.071 12.1 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 AAA_29 PF13555.1 EMC91259.1 - 0.093 12.2 0.5 0.37 10.3 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF463 PF04317.7 EMC91259.1 - 0.11 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_30 PF13604.1 EMC91259.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC91259.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EMC91259.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase Lipocalin_5 PF13924.1 EMC91260.1 - 3.3e-21 75.4 0.0 3.7e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain 7tm_2 PF00002.19 EMC91261.1 - 0.027 13.5 2.7 0.048 12.7 1.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Claudin_2 PF13903.1 EMC91261.1 - 0.32 10.6 5.3 3.5 7.2 0.7 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Lipase_3 PF01764.20 EMC91262.1 - 8.3e-28 96.7 0.0 1.1e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EMC91262.1 - 0.0021 17.8 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC91262.1 - 0.0072 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3463 PF11946.3 EMC91262.1 - 0.062 12.9 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) RRS1 PF04939.7 EMC91266.1 - 7.6e-49 165.3 1.6 8.5e-49 165.1 1.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Tub_2 PF04525.7 EMC91267.1 - 1.5e-22 79.9 0.1 1.8e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 Acyl-CoA_ox_N PF14749.1 EMC91270.1 - 0.023 14.9 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal ATP11 PF06644.6 EMC91271.1 - 5.2e-86 288.4 0.3 6.2e-86 288.2 0.2 1.0 1 0 0 1 1 1 1 ATP11 protein DUF4119 PF13494.1 EMC91271.1 - 0.045 13.7 0.8 0.082 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) MCPVI PF02993.9 EMC91271.1 - 0.059 13.5 5.2 0.09 12.9 3.6 1.3 1 0 0 1 1 1 0 Minor capsid protein VI CAP_N PF01213.14 EMC91271.1 - 0.079 12.2 2.0 0.11 11.7 1.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AMP-binding PF00501.23 EMC91272.1 - 1.1e-102 343.5 0.0 1.3e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC91272.1 - 2e-14 54.2 0.4 1.9e-13 51.1 0.1 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain NMO PF03060.10 EMC91273.1 - 7.6e-69 232.3 1.6 8.9e-69 232.1 1.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EMC91273.1 - 1.5e-05 24.0 2.2 2.2e-05 23.5 1.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMC91273.1 - 0.0021 17.0 0.1 0.017 14.0 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TIM-br_sig_trns PF09370.5 EMC91273.1 - 0.053 12.5 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 TIM-barrel signal transduction protein DUF3173 PF11372.3 EMC91273.1 - 0.12 12.0 0.1 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) FAD_binding_3 PF01494.14 EMC91274.1 - 1.6e-15 57.0 0.1 8e-09 35.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMC91274.1 - 0.0016 18.3 0.1 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF1749 PF08538.5 EMC91275.1 - 4.3e-77 258.9 0.0 4.9e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EMC91275.1 - 1.6e-10 41.2 0.2 2e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC91275.1 - 5e-06 26.3 0.0 1.2e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC91275.1 - 8.9e-05 22.1 0.7 0.021 14.3 0.3 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF900 PF05990.7 EMC91275.1 - 0.00067 19.0 0.0 0.00098 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 EMC91275.1 - 0.0015 18.1 0.1 0.0028 17.2 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Cutinase PF01083.17 EMC91275.1 - 0.002 17.8 0.1 0.0037 17.0 0.1 1.4 1 0 0 1 1 1 1 Cutinase Chlorophyllase2 PF12740.2 EMC91275.1 - 0.04 12.7 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.15 EMC91275.1 - 0.058 13.6 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 EMC91275.1 - 0.07 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3530 PF12048.3 EMC91275.1 - 0.11 11.4 0.0 0.26 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) EthD PF07110.6 EMC91276.1 - 0.036 14.9 0.1 0.26 12.2 0.1 2.2 2 0 0 2 2 2 0 EthD domain C2 PF00168.25 EMC91277.1 - 1.5e-15 56.7 0.0 4.3e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain C2 PF00168.25 EMC91278.1 - 3.4e-18 65.2 0.1 3.4e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain MazG-like PF12643.2 EMC91279.1 - 0.037 13.9 0.2 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 MazG-like family Zn_clus PF00172.13 EMC91279.1 - 1.4 8.8 7.1 4.8 7.1 4.9 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-LYAR PF08790.6 EMC91281.1 - 1.2e-13 50.4 3.6 1.2e-13 50.4 2.5 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger UPF0560 PF10577.4 EMC91281.1 - 1.2 7.3 10.7 0.1 10.8 3.5 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Glyco_hydro_3 PF00933.16 EMC91282.1 - 7.9e-82 274.5 0.0 1.2e-81 274.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMC91282.1 - 1.4e-43 148.9 0.7 2.8e-42 144.7 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMC91282.1 - 9e-20 70.3 0.1 1.7e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABM PF03992.11 EMC91283.1 - 6.5e-06 26.0 0.0 9.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4030 PF13222.1 EMC91283.1 - 0.045 13.4 0.2 0.085 12.5 0.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4030) DUF1170 PF06663.8 EMC91283.1 - 0.072 12.9 0.0 0.087 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) DUF3157 PF11355.3 EMC91283.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Aa_trans PF01490.13 EMC91284.1 - 1.8e-83 280.3 36.5 2.1e-83 280.1 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMC91284.1 - 0.0013 17.6 17.1 0.0013 17.6 11.9 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family EIAV_Rev PF11129.3 EMC91284.1 - 0.021 14.7 0.2 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus GFA PF04828.9 EMC91285.1 - 1.1e-21 76.5 0.6 1.8e-21 75.9 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EMC91285.1 - 0.069 12.3 3.4 0.43 9.8 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 EMC91285.1 - 0.35 10.4 3.9 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RNA_POL_M_15KD PF02150.11 EMC91285.1 - 0.54 10.0 3.7 2.7 7.7 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.1 EMC91285.1 - 0.7 9.6 0.0 0.7 9.6 0.0 2.6 2 0 0 2 2 2 0 Nudix N-terminal C1_1 PF00130.17 EMC91285.1 - 0.89 9.3 6.7 4.6 7.0 0.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 EMC91285.1 - 1.1 8.8 5.2 1.1 8.7 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Securin PF04856.8 EMC91286.1 - 0.009 15.7 0.2 0.094 12.4 0.1 2.5 1 1 0 1 1 1 1 Securin sister-chromatid separation inhibitor Tropomyosin_1 PF12718.2 EMC91287.1 - 4.2e-48 162.8 32.2 4.8e-48 162.6 22.3 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EMC91287.1 - 3.4e-09 36.1 29.5 8.5e-06 25.0 10.6 2.8 1 1 1 2 2 2 2 Tropomyosin Mod_r PF07200.8 EMC91287.1 - 0.00023 21.1 22.0 0.052 13.4 3.0 2.2 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.3 EMC91287.1 - 0.00028 20.6 32.1 0.0037 17.0 9.6 3.1 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EMC91287.1 - 0.00089 19.1 27.3 0.04 13.8 7.8 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Cast PF10174.4 EMC91287.1 - 0.0017 16.5 24.8 0.0018 16.4 17.2 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone TelA PF05816.6 EMC91287.1 - 0.0021 16.8 2.4 0.0021 16.8 1.7 2.3 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) Reo_sigmaC PF04582.7 EMC91287.1 - 0.0037 16.4 3.7 0.031 13.4 0.1 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EMC91287.1 - 0.0045 16.8 27.8 0.0065 16.3 0.9 3.0 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 EMC91287.1 - 0.0053 14.6 21.0 0.006 14.4 14.6 1.1 1 0 0 1 1 1 1 HOOK protein Striatin PF08232.7 EMC91287.1 - 0.0068 16.7 21.7 0.24 11.6 6.7 2.0 1 1 1 2 2 2 2 Striatin family NPV_P10 PF05531.7 EMC91287.1 - 0.0069 16.6 10.2 1.6 9.0 0.1 3.3 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 EMC91287.1 - 0.0069 14.3 14.8 0.0087 13.9 10.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GAS PF13851.1 EMC91287.1 - 0.0081 15.3 29.1 0.02 14.1 20.2 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding ERM PF00769.14 EMC91287.1 - 0.0096 15.4 30.6 0.012 15.1 6.2 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Laminin_II PF06009.7 EMC91287.1 - 0.012 15.3 5.1 0.012 15.3 3.6 2.2 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.6 EMC91287.1 - 0.031 12.9 25.1 0.4 9.2 5.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 EMC91287.1 - 0.036 13.1 30.4 0.39 9.7 8.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 EMC91287.1 - 0.039 13.7 25.6 1.8 8.3 5.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EMC91287.1 - 0.044 13.9 17.7 0.13 12.3 2.6 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.14 EMC91287.1 - 0.054 11.2 29.1 0.48 8.0 7.5 1.5 1 1 0 1 1 1 0 Myosin tail TMF_TATA_bd PF12325.3 EMC91287.1 - 0.064 12.9 25.1 0.47 10.1 13.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 EMC91287.1 - 0.079 12.9 30.8 4.8 7.1 6.8 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Filament PF00038.16 EMC91287.1 - 0.096 12.1 25.2 1.1 8.6 5.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein IncA PF04156.9 EMC91287.1 - 0.1 12.1 24.8 2.3 7.8 17.2 2.1 1 1 0 1 1 1 0 IncA protein KLRAQ PF10205.4 EMC91287.1 - 0.11 12.5 18.7 0.045 13.7 5.6 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Rab5-bind PF09311.6 EMC91287.1 - 0.11 12.3 22.8 0.13 12.0 15.8 1.1 1 0 0 1 1 1 0 Rabaptin-like protein TBPIP PF07106.8 EMC91287.1 - 0.12 11.9 25.7 0.66 9.5 8.9 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EMC91287.1 - 0.13 12.2 24.7 0.72 9.8 0.1 3.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4201 PF13870.1 EMC91287.1 - 0.18 11.2 24.3 0.46 9.9 16.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) BLOC1_2 PF10046.4 EMC91287.1 - 0.21 11.7 22.1 1.8 8.7 4.6 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 EMC91287.1 - 0.22 9.6 22.6 0.2 9.7 3.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CCDC155 PF14662.1 EMC91287.1 - 0.24 10.9 28.2 0.97 8.9 5.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF1664 PF07889.7 EMC91287.1 - 0.32 10.8 14.9 0.72 9.6 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vps5 PF09325.5 EMC91287.1 - 0.35 10.0 22.2 0.02 14.1 5.0 2.9 1 1 2 3 3 3 0 Vps5 C terminal like IFT46_B_C PF12317.3 EMC91287.1 - 0.35 10.1 12.2 0.023 14.0 2.6 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Jnk-SapK_ap_N PF09744.4 EMC91287.1 - 0.36 10.8 25.0 0.45 10.4 5.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMP_2 PF06791.8 EMC91287.1 - 0.47 10.0 6.2 0.22 11.1 1.9 1.8 1 1 1 2 2 2 0 Prophage tail length tape measure protein Orbi_VP5 PF00901.12 EMC91287.1 - 0.54 8.3 15.9 0.67 8.0 11.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Transposase_22 PF02994.9 EMC91287.1 - 0.54 8.6 20.6 0.56 8.6 13.6 1.5 1 1 0 1 1 1 0 L1 transposable element DUF812 PF05667.6 EMC91287.1 - 0.62 8.5 25.9 0.92 7.9 9.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) BRE1 PF08647.6 EMC91287.1 - 0.62 10.0 27.8 2.6 8.0 2.5 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.9 EMC91287.1 - 0.63 9.6 25.9 1.8 8.1 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Lebercilin PF15619.1 EMC91287.1 - 0.65 9.3 26.3 1.7 7.9 4.1 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MAD PF05557.8 EMC91287.1 - 0.65 8.0 25.8 6.1 4.8 17.0 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein bZIP_1 PF00170.16 EMC91287.1 - 0.66 9.9 28.2 0.78 9.7 1.3 4.9 2 2 3 5 5 5 0 bZIP transcription factor Atg14 PF10186.4 EMC91287.1 - 0.87 8.4 23.7 0.18 10.7 11.4 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 EMC91287.1 - 0.88 8.7 23.3 3.3 6.8 6.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.1 EMC91287.1 - 1.6 9.2 17.4 3.8 8.0 3.0 2.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.4 EMC91287.1 - 1.6 8.5 27.3 1.9 8.3 2.4 3.0 1 1 2 3 3 3 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.7 EMC91287.1 - 1.6 8.5 31.4 3 7.5 8.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EMC91287.1 - 1.6 8.6 31.3 0.62 10.0 0.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Phage_GP20 PF06810.6 EMC91287.1 - 1.7 8.0 27.0 0.81 9.1 8.1 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 EMC91287.1 - 1.7 8.5 18.4 5.5 6.9 4.4 4.0 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) CAGE1 PF15066.1 EMC91287.1 - 1.8 6.9 20.6 4.5 5.5 14.3 1.6 1 1 0 1 1 1 0 Cancer-associated gene protein 1 family SlyX PF04102.7 EMC91287.1 - 1.8 8.9 16.6 12 6.3 0.2 3.4 1 1 1 3 3 3 0 SlyX Uds1 PF15456.1 EMC91287.1 - 1.8 8.5 22.4 24 4.9 0.7 3.1 1 1 1 2 2 2 0 Up-regulated During Septation DUF3584 PF12128.3 EMC91287.1 - 1.9 5.6 23.5 2.8 5.1 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nup54 PF13874.1 EMC91287.1 - 2.1 8.0 21.6 15 5.2 11.7 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CALCOCO1 PF07888.6 EMC91287.1 - 2.1 6.5 20.4 2.5 6.3 14.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 EMC91287.1 - 2.4 8.5 24.0 2.4 8.5 8.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMCO5 PF14992.1 EMC91287.1 - 2.4 7.2 24.4 2.1 7.4 9.2 2.1 1 1 1 2 2 2 0 TMCO5 family EHN PF06441.7 EMC91287.1 - 2.8 7.9 11.1 0.4 10.6 2.0 2.3 1 1 0 2 2 2 0 Epoxide hydrolase N terminus WXG100 PF06013.7 EMC91287.1 - 2.9 7.9 13.3 3.1 7.8 0.2 3.5 1 1 1 3 3 3 0 Proteins of 100 residues with WXG HalX PF08663.5 EMC91287.1 - 3 7.8 13.1 9.2 6.3 0.0 4.1 1 1 1 4 4 4 0 HalX domain Fmp27_WPPW PF10359.4 EMC91287.1 - 3.4 5.9 23.5 4.7 5.5 8.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FH2 PF02181.18 EMC91287.1 - 3.5 6.4 18.5 0.72 8.6 2.7 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain Mnd1 PF03962.10 EMC91287.1 - 3.7 7.1 27.9 3.3 7.3 8.6 2.1 1 1 1 2 2 2 0 Mnd1 family DUF3540 PF12059.3 EMC91287.1 - 3.9 7.0 9.5 1.1 8.8 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) Nsp1_C PF05064.8 EMC91287.1 - 4.2 7.0 20.4 3.5 7.2 0.5 3.0 1 1 2 3 3 3 0 Nsp1-like C-terminal region DUF3086 PF11285.3 EMC91287.1 - 5.2 5.7 12.2 5.7 5.6 7.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) ApoO PF09769.4 EMC91287.1 - 5.3 6.7 8.9 2e+02 1.5 6.1 2.3 1 1 0 1 1 1 0 Apolipoprotein O NABP PF07990.7 EMC91287.1 - 6.3 5.9 7.0 6.7 5.8 4.9 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF2730 PF10805.3 EMC91287.1 - 6.6 6.5 14.9 1.4 8.7 4.2 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF3287 PF11690.3 EMC91287.1 - 7.1 6.7 13.1 1.5 8.9 0.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) CDC37_N PF03234.9 EMC91287.1 - 7.4 6.8 22.5 36 4.6 15.6 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Lge1 PF11488.3 EMC91287.1 - 8.4 6.6 18.5 3.2 8.0 3.1 2.4 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Exonuc_VII_L PF02601.10 EMC91287.1 - 8.6 5.4 16.0 12 4.9 11.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit YscO PF07321.7 EMC91287.1 - 8.6 6.1 25.8 1.1 9.0 13.4 2.3 1 1 2 3 3 3 0 Type III secretion protein YscO AAA_13 PF13166.1 EMC91287.1 - 8.9 4.6 24.0 39 2.5 16.6 1.8 1 1 0 1 1 1 0 AAA domain DUF641 PF04859.7 EMC91287.1 - 9.8 5.9 21.6 0.7 9.6 5.3 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Nop25 PF09805.4 EMC91288.1 - 8.1e-32 110.1 10.7 8.1e-32 110.1 7.4 2.5 1 1 2 3 3 3 1 Nucleolar protein 12 (25kDa) Tmemb_9 PF05434.6 EMC91288.1 - 0.27 10.9 6.4 0.038 13.7 1.4 1.8 2 0 0 2 2 2 0 TMEM9 ATP-synt_S1 PF05827.7 EMC91289.1 - 3.1e-18 66.0 0.0 5.1e-18 65.3 0.0 1.3 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DAHP_synth_1 PF00793.15 EMC91290.1 - 2.5e-97 324.8 0.1 3.2e-97 324.4 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2834 PF11196.3 EMC91294.1 - 2.8e-05 24.2 13.8 0.002 18.2 0.9 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2834) Pyr_redox_3 PF13738.1 EMC91295.1 - 3.4e-18 66.4 0.0 1.2e-17 64.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC91295.1 - 1.3e-15 56.6 0.1 2e-13 49.3 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMC91295.1 - 9.1e-10 38.4 0.0 8.5e-09 35.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMC91295.1 - 5.8e-06 25.4 0.1 0.00016 20.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMC91295.1 - 0.0021 17.0 0.0 0.23 10.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC91295.1 - 0.053 13.3 1.2 1.1 8.9 0.0 3.1 4 1 1 5 5 5 0 FAD-NAD(P)-binding Thi4 PF01946.12 EMC91295.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ATP_bind_4 PF01902.12 EMC91296.1 - 8.8e-19 67.7 0.0 4.5e-17 62.1 0.0 2.2 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EMC91296.1 - 4.4e-14 52.2 0.0 2e-07 30.8 0.0 3.2 3 0 0 3 3 3 2 Endoribonuclease L-PSP Frag1 PF10277.4 EMC91298.1 - 4.9e-46 156.9 14.6 5.8e-46 156.6 10.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLAC1 PF03595.12 EMC91298.1 - 2e-05 23.4 13.2 2.8e-05 22.9 9.2 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1794 PF08768.6 EMC91298.1 - 0.089 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) Tetraspannin PF00335.15 EMC91298.1 - 0.13 11.4 10.5 0.07 12.3 2.8 2.3 2 0 0 2 2 2 0 Tetraspanin family Cation_efflux PF01545.16 EMC91298.1 - 1.1 8.2 9.0 1.6 7.7 6.3 1.2 1 0 0 1 1 1 0 Cation efflux family Ribosomal_L36e PF01158.13 EMC91299.1 - 1.5e-41 140.3 6.3 1.7e-41 140.1 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EMC91299.1 - 0.066 12.3 0.1 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 LemA family PITH PF06201.8 EMC91300.1 - 6.1e-42 142.9 0.0 8.9e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EMC91300.1 - 1.1e-28 98.9 0.0 2.1e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMC91300.1 - 9.9e-08 32.0 0.1 0.00062 19.8 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC91300.1 - 6e-07 29.6 0.3 3.5e-06 27.1 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EMC91300.1 - 0.0056 16.2 0.2 1.7 8.2 0.0 2.7 2 1 1 3 3 3 1 Redoxin AhpC-TSA PF00578.16 EMC91300.1 - 0.015 15.0 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.1 EMC91300.1 - 0.016 15.2 0.0 0.045 13.7 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 EMC91300.1 - 0.028 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TUG-UBL1 PF11470.3 EMC91301.1 - 3.5e-23 81.2 0.1 7.3e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 EMC91301.1 - 4.1e-07 29.6 0.0 3.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Raf-like Ras-binding domain UBX PF00789.15 EMC91301.1 - 0.0015 18.5 0.0 0.012 15.6 0.0 2.4 3 0 0 3 3 3 1 UBX domain UN_NPL4 PF11543.3 EMC91301.1 - 0.023 14.9 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 zf-C2H2 PF00096.21 EMC91302.1 - 1.4e-12 47.1 14.5 4.3e-07 29.8 1.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC91302.1 - 1.3e-10 40.8 11.3 0.00012 22.1 0.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC91302.1 - 1.5e-06 28.1 14.2 6.1e-05 23.1 4.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC91302.1 - 3.1e-06 27.1 6.7 0.0037 17.3 1.2 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC91302.1 - 0.00026 21.0 9.0 0.0034 17.5 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC91302.1 - 0.00026 20.7 0.8 0.00026 20.7 0.5 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger LIM PF00412.17 EMC91302.1 - 0.18 11.9 4.1 0.42 10.7 2.8 1.7 1 0 0 1 1 1 0 LIM domain NAD_binding_4 PF07993.7 EMC91304.1 - 1.3e-46 158.5 0.0 2.3e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMC91304.1 - 2.6e-24 85.3 0.0 4.3e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMC91304.1 - 3.1e-08 33.3 0.0 6.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMC91304.1 - 2.9e-07 30.6 0.0 9.3e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EMC91304.1 - 8.6e-05 22.5 0.7 0.00023 21.1 0.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EMC91304.1 - 0.0011 17.6 0.0 0.0075 14.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMC91304.1 - 0.023 14.3 0.5 0.066 12.8 0.3 1.8 1 1 0 1 1 1 0 KR domain GH3 PF03321.8 EMC91304.1 - 0.12 10.9 0.0 0.24 9.8 0.0 1.4 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Polysacc_synt_2 PF02719.10 EMC91304.1 - 0.24 10.2 0.1 0.52 9.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein G-patch_2 PF12656.2 EMC91305.1 - 4.4e-26 90.5 0.4 4.4e-26 90.5 0.3 3.2 3 0 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 EMC91305.1 - 6.3e-05 22.6 1.5 0.00015 21.4 1.1 1.8 1 0 0 1 1 1 1 G-patch domain Glyco_transf_8 PF01501.15 EMC91306.1 - 9.5e-13 48.0 0.0 2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 MIP-T3 PF10243.4 EMC91307.1 - 4.6 5.5 21.0 16 3.7 14.5 1.8 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 MutS_V PF00488.16 EMC91310.1 - 4.2e-88 294.7 0.0 7e-88 293.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC91310.1 - 7.4e-36 123.8 5.3 7.5e-36 123.8 2.4 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EMC91310.1 - 4.1e-29 100.8 0.0 1.1e-28 99.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMC91310.1 - 4.2e-10 39.8 0.1 9.8e-09 35.3 0.0 3.2 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EMC91310.1 - 1.9e-05 24.7 0.1 0.0001 22.4 0.1 2.3 1 0 0 1 1 1 1 MutS family domain IV Velvet PF11754.3 EMC91312.1 - 8.3e-68 227.9 0.2 2.2e-67 226.6 0.0 1.7 2 0 0 2 2 2 1 Velvet factor APG5 PF04106.7 EMC91313.1 - 1.3e-61 207.5 0.0 1.5e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Lactonase PF10282.4 EMC91314.1 - 2.2e-19 69.7 0.0 2.8e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.15 EMC91314.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Arylesterase SGL PF08450.7 EMC91314.1 - 0.13 11.6 0.0 0.69 9.2 0.0 1.9 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region WD40 PF00400.27 EMC91316.1 - 3.2e-35 118.7 18.4 4.3e-08 32.7 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 EMC91316.1 - 1.3e-19 69.9 0.4 2.4e-19 69.1 0.3 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EMC91316.1 - 0.00044 18.5 6.5 0.15 10.1 0.6 3.3 2 1 0 3 3 3 3 Nucleoporin Nup120/160 INSIG PF07281.7 EMC91317.1 - 6.3e-52 175.7 1.0 7.9e-52 175.4 0.7 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AICARFT_IMPCHas PF01808.13 EMC91318.1 - 7.7e-111 370.1 0.0 1e-110 369.7 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EMC91318.1 - 1.3e-23 82.7 0.0 2.2e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Myb_DNA-bind_6 PF13921.1 EMC91319.1 - 1.1e-20 73.5 0.3 3.2e-05 23.9 0.0 5.4 5 1 1 6 6 6 3 Myb-like DNA-binding domain HTH_38 PF13936.1 EMC91319.1 - 8.4e-11 41.2 2.1 0.001 18.5 0.1 5.0 5 0 0 5 5 5 3 Helix-turn-helix domain Myb_DNA-binding PF00249.26 EMC91319.1 - 1.6e-10 40.8 4.7 2.9e-05 24.0 0.0 4.8 5 1 0 5 5 5 2 Myb-like DNA-binding domain GcrA PF07750.6 EMC91319.1 - 3.7e-06 27.2 0.3 0.034 14.3 0.1 3.4 3 1 0 3 3 3 2 GcrA cell cycle regulator Sigma70_r4_2 PF08281.7 EMC91319.1 - 0.00057 19.3 0.5 15 5.1 0.0 4.9 6 0 0 6 6 6 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EMC91319.1 - 0.0028 17.1 0.2 0.52 9.8 0.0 3.4 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_28 PF13518.1 EMC91319.1 - 0.0036 17.2 0.1 0.095 12.7 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain GerE PF00196.14 EMC91319.1 - 0.01 15.1 0.1 0.35 10.2 0.0 3.1 3 1 0 3 3 3 0 Bacterial regulatory proteins, luxR family HTH_Tnp_Tc3_1 PF11427.3 EMC91319.1 - 0.029 13.9 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase Sigma70_r4 PF04545.11 EMC91319.1 - 0.054 12.8 0.2 6.7 6.1 0.0 3.7 3 1 0 3 3 3 0 Sigma-70, region 4 Nup54 PF13874.1 EMC91319.1 - 0.088 12.4 0.5 0.35 10.5 0.2 2.0 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 PMM PF03332.8 EMC91320.1 - 5.4e-102 340.0 0.1 6.4e-102 339.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EMC91320.1 - 8.6e-06 25.5 0.0 3e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EMC91320.1 - 0.0009 18.6 0.0 0.99 8.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 EMC91320.1 - 0.00097 18.3 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein Hydrolase PF00702.21 EMC91320.1 - 0.019 15.4 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EMC91320.1 - 0.058 12.2 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase GTP_EFTU PF00009.22 EMC91321.1 - 2.5e-38 131.3 0.0 4.2e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EMC91321.1 - 1.8e-36 124.0 0.5 3.5e-36 123.1 0.3 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EMC91321.1 - 4.1e-12 46.0 0.2 1e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC91321.1 - 0.0067 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC91321.1 - 0.1 12.4 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Stm1_N PF09598.5 EMC91321.1 - 0.89 10.2 6.5 2.7 8.7 4.5 1.8 1 0 0 1 1 1 0 Stm1 Cpn60_TCP1 PF00118.19 EMC91322.1 - 5.7e-133 444.0 5.4 6.8e-133 443.8 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ADH_zinc_N PF00107.21 EMC91324.1 - 7e-26 90.2 0.7 1.2e-25 89.6 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC91324.1 - 1.2e-14 55.3 0.0 2.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EMC91324.1 - 4e-05 23.3 0.0 6.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.7 EMC91324.1 - 0.00025 20.7 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 EMC91325.1 - 6.3e-54 182.5 0.0 7.4e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC91325.1 - 4.8e-33 114.5 0.1 6.3e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC91325.1 - 9e-17 60.8 0.0 2.5e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMC91325.1 - 1e-13 51.5 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMC91325.1 - 6.9e-12 44.8 0.0 8.9e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EMC91325.1 - 5.9e-08 32.5 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMC91325.1 - 6.5e-08 31.8 0.0 1.4e-06 27.4 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMC91325.1 - 9.4e-08 32.2 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EMC91325.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.19 EMC91326.1 - 5.2e-64 216.4 27.2 6.6e-64 216.1 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC91326.1 - 2.4e-19 69.3 35.0 8.7e-17 60.8 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2839 PF10999.3 EMC91326.1 - 3.6 7.6 6.9 0.75 9.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Acetyltransf_3 PF13302.1 EMC91327.1 - 6.9e-27 94.3 0.0 8.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMC91327.1 - 2.3e-07 30.8 0.3 2.1e-05 24.4 0.1 2.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC91327.1 - 1.1e-05 25.3 0.0 8.5e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMC91327.1 - 4.9e-05 22.9 0.0 0.28 10.9 0.0 2.2 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.1 EMC91327.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC91327.1 - 0.04 14.0 0.0 2 8.5 0.0 2.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 EMC91328.1 - 3.1e-56 190.7 38.9 1.5e-35 123.0 13.6 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EMC91328.1 - 4.7e-45 153.2 0.3 3e-27 95.5 0.0 3.5 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EMC91328.1 - 3.1e-06 27.3 0.0 5.6 6.8 0.0 4.3 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EMC91328.1 - 7.2e-06 25.9 0.3 0.19 11.7 0.2 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.14 EMC91328.1 - 1.5e-05 24.3 0.3 0.11 11.6 0.0 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 EMC91328.1 - 2.5e-05 23.4 0.1 0.021 13.9 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 EMC91328.1 - 5.1e-05 23.7 1.4 0.22 12.0 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EMC91328.1 - 0.00024 21.1 0.8 0.43 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMC91328.1 - 0.0013 18.2 5.0 0.1 12.1 0.2 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMC91328.1 - 0.0068 15.6 1.8 1.6 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC91328.1 - 0.014 16.1 2.7 8.9 7.1 0.0 3.4 2 1 0 3 3 2 0 AAA domain ArgK PF03308.11 EMC91328.1 - 0.022 13.5 1.4 3.2 6.4 0.2 2.5 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 EMC91328.1 - 0.028 13.8 0.2 8 5.7 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EMC91328.1 - 0.049 13.7 1.2 13 5.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMC91328.1 - 0.051 12.9 0.1 4 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMC91328.1 - 0.071 12.5 0.2 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EMC91328.1 - 0.097 12.3 1.3 14 5.3 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EMC91328.1 - 0.16 11.5 2.7 5.9 6.3 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 EMC91328.1 - 0.2 11.4 10.4 0.34 10.6 0.6 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF87 Auxin_repressed PF05564.7 EMC91328.1 - 3.1 8.4 7.8 0.29 11.7 1.3 2.2 2 0 0 2 2 2 0 Dormancy/auxin associated protein AAA PF00004.24 EMC91329.1 - 5.5e-14 52.4 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC91329.1 - 0.0046 17.0 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC91329.1 - 0.011 15.4 0.0 0.058 13.1 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EMC91329.1 - 0.019 14.9 0.0 0.076 13.0 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 EMC91329.1 - 0.042 14.0 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EMC91329.1 - 0.089 12.3 0.0 0.63 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EMC91329.1 - 0.12 11.0 0.0 10 4.8 0.1 2.7 1 1 2 3 3 3 0 SNF2 family N-terminal domain Glyco_hydro_16 PF00722.16 EMC91329.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 zf-H2C2_2 PF13465.1 EMC91330.1 - 3e-15 55.6 17.4 1.7e-08 34.3 1.6 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC91330.1 - 7.3e-11 41.7 24.1 0.0045 17.2 5.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC91330.1 - 1e-06 28.6 22.0 0.016 15.4 4.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC91330.1 - 0.00047 19.9 13.8 0.0086 15.9 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC91330.1 - 0.002 18.1 10.5 0.6 10.3 1.9 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMC91330.1 - 0.012 15.7 6.2 0.026 14.6 4.3 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.4 EMC91330.1 - 0.038 13.8 5.7 0.8 9.5 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HC_2 PF13913.1 EMC91330.1 - 0.37 10.5 6.1 0.15 11.7 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.2 EMC91330.1 - 0.58 10.0 6.6 6.8 6.5 4.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon GAGA PF09237.6 EMC91330.1 - 0.84 9.2 8.6 0.37 10.4 1.1 2.8 1 1 2 3 3 3 0 GAGA factor zf-CHY PF05495.7 EMC91330.1 - 1.3 9.2 7.6 2.6 8.2 5.3 1.5 1 0 0 1 1 1 0 CHY zinc finger Zn-ribbon_8 PF09723.5 EMC91330.1 - 2.7 8.0 9.4 20 5.2 2.6 3.1 1 1 2 3 3 3 0 Zinc ribbon domain Glyco_hydro_76 PF03663.9 EMC91332.1 - 1e-49 169.8 26.6 1.7e-49 169.1 18.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Pyr_redox_3 PF13738.1 EMC91333.1 - 2.1e-24 86.7 0.0 6.6e-24 85.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC91333.1 - 2.5e-14 52.4 0.0 2.7e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMC91333.1 - 2.4e-12 46.6 0.0 2.7e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMC91333.1 - 2.6e-08 33.2 0.0 0.0012 17.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EMC91333.1 - 2.7e-07 29.8 0.5 0.00011 21.2 0.0 2.9 3 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EMC91333.1 - 3.5e-06 26.1 0.0 0.005 15.8 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMC91333.1 - 3.8e-06 26.9 0.1 0.011 15.5 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC91333.1 - 4.1e-06 27.0 0.1 0.044 14.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC91333.1 - 7.4e-05 21.8 0.1 0.00044 19.2 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EMC91333.1 - 0.00029 20.9 0.0 0.016 15.2 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EMC91333.1 - 0.00092 19.0 0.2 0.11 12.2 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Mqo PF06039.10 EMC91333.1 - 0.0039 15.4 0.0 0.3 9.2 0.0 2.5 3 0 0 3 3 3 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 EMC91333.1 - 0.0065 15.3 0.0 0.11 11.3 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain DUF3317 PF11779.3 EMC91333.1 - 0.012 15.0 0.6 0.023 14.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) NAD_binding_7 PF13241.1 EMC91333.1 - 0.019 15.2 0.0 0.053 13.7 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding ApbA PF02558.11 EMC91333.1 - 0.034 13.6 0.0 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_transf_20 PF00982.16 EMC91334.1 - 1.6e-155 518.1 0.1 2.8e-155 517.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EMC91334.1 - 5.5e-39 133.4 0.0 1.4e-38 132.1 0.0 1.7 1 0 0 1 1 1 1 Trehalose-phosphatase DUF3990 PF13151.1 EMC91334.1 - 0.047 13.0 0.4 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) GPW_gp25 PF04965.9 EMC91334.1 - 0.07 12.6 0.1 4.3 6.9 0.0 2.8 3 0 0 3 3 3 0 Gene 25-like lysozyme Cyclin PF08613.6 EMC91335.1 - 2.5e-39 135.0 7.3 6.2e-23 81.8 0.2 2.8 3 1 0 3 3 3 2 Cyclin DUF2524 PF10732.4 EMC91335.1 - 0.037 14.1 0.2 0.08 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Proteasome PF00227.21 EMC91336.1 - 1e-47 161.8 0.2 1.2e-47 161.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit SNF2_N PF00176.18 EMC91337.1 - 1.2e-57 195.0 0.0 5.3e-57 192.8 0.0 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 EMC91337.1 - 7.1e-10 38.4 7.9 1.3e-09 37.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC91337.1 - 1e-09 38.0 10.8 1e-09 38.0 7.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC91337.1 - 1.3e-08 34.6 10.6 3e-08 33.5 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC91337.1 - 2.3e-08 33.5 10.4 4.9e-08 32.4 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC91337.1 - 8.1e-06 25.4 10.1 1.6e-05 24.5 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC91337.1 - 2.5e-05 24.2 7.2 7e-05 22.8 5.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC91337.1 - 0.0004 20.1 9.6 0.001 18.9 6.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC91337.1 - 0.002 17.8 6.4 0.0051 16.4 4.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 EMC91337.1 - 0.0076 15.9 0.6 0.022 14.5 0.4 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EMC91337.1 - 0.011 15.2 5.2 0.024 14.1 3.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Helicase_C PF00271.26 EMC91337.1 - 0.023 14.5 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Rad50_zn_hook PF04423.9 EMC91337.1 - 0.044 13.2 0.1 0.17 11.3 0.1 2.0 1 0 0 1 1 1 0 Rad50 zinc hook motif Cript PF10235.4 EMC91337.1 - 0.063 13.6 3.9 0.027 14.8 0.7 1.8 2 0 0 2 2 1 0 Microtubule-associated protein CRIPT Pico_P2A PF00947.14 EMC91337.1 - 0.091 12.5 0.4 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 Picornavirus core protein 2A zf-RING_4 PF14570.1 EMC91337.1 - 8.3 6.0 11.0 20 4.8 7.6 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MFS_1 PF07690.11 EMC91338.1 - 4.1e-21 75.0 23.4 6e-19 67.9 11.4 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Trm112p PF03966.11 EMC91339.1 - 2.9e-14 53.1 0.1 4.7e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EMC91339.1 - 0.013 15.7 0.2 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF1451 PF07295.6 EMC91339.1 - 0.14 11.9 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF2554 PF10829.3 EMC91339.1 - 0.14 12.2 1.3 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) Rad60-SLD PF11976.3 EMC91342.1 - 1.5e-15 56.6 0.1 8.9e-15 54.1 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 EMC91342.1 - 0.08 12.8 0.0 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Methyltransf_11 PF08241.7 EMC91343.1 - 2.1e-17 63.3 0.0 4.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC91343.1 - 3.6e-10 40.4 0.0 8.9e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC91343.1 - 3e-09 36.3 0.0 5.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EMC91343.1 - 4.2e-09 36.1 0.0 1.2e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC91343.1 - 1.5e-08 34.6 0.0 3.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC91343.1 - 2.6e-08 33.7 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC91343.1 - 3.5e-08 33.8 0.0 8.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC91343.1 - 2.8e-06 27.5 0.0 5.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMC91343.1 - 0.00019 21.1 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.14 EMC91343.1 - 0.028 14.3 0.0 0.051 13.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.7 EMC91343.1 - 0.091 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Atg14 PF10186.4 EMC91346.1 - 1.6 7.6 8.1 2.6 6.9 5.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Arrestin_N PF00339.24 EMC91349.1 - 4.2e-16 59.1 0.0 2.7e-15 56.4 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Response_reg PF00072.19 EMC91350.1 - 2.6e-19 69.2 0.2 8.5e-19 67.6 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EMC91350.1 - 5.8e-18 64.6 0.0 1.1e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMC91350.1 - 8.3e-06 25.7 0.0 2.7e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EMC91350.1 - 0.0019 18.7 0.0 0.0077 16.7 0.0 2.1 1 0 0 1 1 1 1 GAF domain FimP PF09766.4 EMC91351.1 - 1.2e-22 80.5 13.0 1.4e-22 80.2 9.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 EMC91351.1 - 0.031 14.0 0.8 0.031 14.0 0.6 2.8 2 2 0 2 2 2 0 K-box region HCMV_UL139 PF12507.3 EMC91351.1 - 0.046 13.8 8.2 3 8.0 5.7 2.2 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein Mnd1 PF03962.10 EMC91351.1 - 0.29 10.7 12.0 1.7 8.3 3.2 2.4 2 0 0 2 2 2 0 Mnd1 family BLOC1_2 PF10046.4 EMC91351.1 - 0.51 10.5 6.4 0.16 12.1 0.8 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.1 EMC91351.1 - 1.1 9.7 14.5 6 7.3 2.2 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) NMO PF03060.10 EMC91352.1 - 3e-34 118.6 6.9 1.8e-32 112.8 4.8 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EMC91352.1 - 3.4e-07 29.4 0.6 6.7e-07 28.4 0.4 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMC91352.1 - 0.00021 20.3 1.7 0.23 10.3 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMC91352.1 - 0.072 11.9 3.0 0.047 12.6 0.4 1.7 2 0 0 2 2 2 0 Conserved region in glutamate synthase RabGAP-TBC PF00566.13 EMC91353.1 - 2e-33 115.6 0.0 3.3e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HlyIII PF03006.15 EMC91355.1 - 6e-58 195.8 20.1 7.4e-58 195.5 13.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 EMC91355.1 - 3.1 7.6 5.6 0.79 9.5 1.0 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) p450 PF00067.17 EMC91356.1 - 1.8e-52 178.4 0.0 2.3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF221 PF02714.10 EMC91357.1 - 5.4e-90 301.5 20.4 5.4e-90 301.5 14.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMC91357.1 - 5.3e-42 143.0 1.1 5.3e-42 143.0 0.8 2.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMC91357.1 - 4.6e-17 62.3 0.0 7.9e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EMC91357.1 - 0.036 14.0 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GET2 PF08690.5 EMC91357.1 - 1.4 8.0 3.5 2.6 7.1 2.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 AAA PF00004.24 EMC91359.1 - 6.7e-30 103.9 0.0 1.3e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC91359.1 - 3e-07 31.2 0.1 1.5e-06 29.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC91359.1 - 8.2e-07 29.3 0.0 8.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC91359.1 - 1e-06 28.9 0.0 3.1e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EMC91359.1 - 2.6e-06 27.3 0.1 5.3e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC91359.1 - 6.3e-06 25.7 0.1 0.038 13.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC91359.1 - 1.2e-05 25.4 0.2 5e-05 23.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EMC91359.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC91359.1 - 0.00049 19.7 0.0 0.0019 17.9 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EMC91359.1 - 0.0005 20.1 0.3 0.00093 19.3 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Arch_ATPase PF01637.13 EMC91359.1 - 0.00054 19.7 0.0 0.043 13.4 0.0 2.3 1 1 0 1 1 1 1 Archaeal ATPase Sigma54_activat PF00158.21 EMC91359.1 - 0.00079 18.9 0.1 0.0018 17.7 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain NACHT PF05729.7 EMC91359.1 - 0.0013 18.3 0.0 0.0032 17.1 0.0 1.8 1 1 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.16 EMC91359.1 - 0.003 16.7 0.0 0.027 13.6 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EMC91359.1 - 0.0035 16.8 0.0 0.008 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EMC91359.1 - 0.0043 17.3 0.0 0.0075 16.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.13 EMC91359.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 EMC91359.1 - 0.0093 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EMC91359.1 - 0.01 15.8 0.0 0.034 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.9 EMC91359.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EMC91359.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMC91359.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EMC91359.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EMC91359.1 - 0.018 13.5 0.1 0.026 13.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EMC91359.1 - 0.021 13.5 0.1 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EMC91359.1 - 0.022 13.8 0.0 0.046 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 EMC91359.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_2 PF07724.9 EMC91359.1 - 0.033 14.1 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EMC91359.1 - 0.039 13.0 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EMC91359.1 - 0.049 12.6 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 EMC91359.1 - 0.055 12.3 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EMC91359.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ADK PF00406.17 EMC91359.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase ATP_bind_1 PF03029.12 EMC91359.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EMC91359.1 - 0.074 12.4 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain SKI PF01202.17 EMC91359.1 - 0.074 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_30 PF13604.1 EMC91359.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EMC91359.1 - 0.096 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EMC91359.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EMC91359.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EMC91359.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 NTPase Zot PF05707.7 EMC91359.1 - 0.16 11.3 0.0 1 8.7 0.0 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Cytidylate_kin2 PF13189.1 EMC91359.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Myb_DNA-bind_6 PF13921.1 EMC91360.1 - 1.9e-10 40.6 8.7 2.2e-10 40.4 3.0 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.8 EMC91360.1 - 4.4e-10 39.2 3.4 4.4e-10 39.2 2.3 5.5 8 0 0 8 8 8 1 HSA WD40 PF00400.27 EMC91361.1 - 9.4e-15 53.8 0.2 4.5e-05 23.1 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat N-SET PF11764.3 EMC91362.1 - 2e-46 157.9 0.2 2e-46 157.9 0.2 2.7 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EMC91362.1 - 3.5e-23 80.6 0.0 7.2e-23 79.6 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EMC91362.1 - 7.2e-23 81.6 0.1 7.2e-23 81.6 0.1 2.9 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.17 EMC91362.1 - 0.00049 19.6 0.3 0.0061 16.1 0.1 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMRL_synthase PF00885.14 EMC91363.1 - 1.4e-42 144.7 0.0 1.1e-23 83.4 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Transgly_assoc PF04226.8 EMC91363.1 - 0.1 12.6 0.7 0.33 11.0 0.5 1.8 1 0 0 1 1 1 0 Transglycosylase associated protein eIF2A PF08662.6 EMC91364.1 - 5.9e-39 133.7 7.6 3e-37 128.2 0.4 4.5 3 3 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EMC91364.1 - 3e-07 30.3 0.0 6.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC91364.1 - 6.3e-07 28.9 0.0 1.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC91364.1 - 9.9e-06 25.3 0.0 4.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EMC91364.1 - 4.4e-05 23.1 0.1 0.14 12.0 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EMC91364.1 - 0.003 16.4 0.0 0.54 8.9 0.0 2.9 2 1 1 3 3 3 1 Coatomer WD associated region DUF2497 PF10691.4 EMC91364.1 - 0.013 15.4 3.1 0.013 15.4 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) RRM_2 PF04059.7 EMC91364.1 - 0.017 15.0 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif 2 DUF3883 PF13020.1 EMC91365.1 - 4.1e-06 26.4 0.0 1.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.1 EMC91365.1 - 0.0041 16.7 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AlaDh_PNT_N PF05222.10 EMC91366.1 - 1.6e-28 99.3 0.0 3e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EMC91366.1 - 1.4e-10 41.0 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 EMC91367.1 - 7.8e-69 231.7 0.0 1.2e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC91367.1 - 5.6e-43 146.8 0.0 7.8e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC91367.1 - 3.3e-12 45.9 0.0 3e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC91367.1 - 0.0026 16.8 0.1 0.0099 14.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC91367.1 - 0.0039 16.9 3.1 2.1 8.0 0.1 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family AP_endonuc_2 PF01261.19 EMC91368.1 - 2.3e-34 118.5 0.0 3.4e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Methyltransf_12 PF08242.7 EMC91369.1 - 2.1e-07 31.3 0.0 3.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC91369.1 - 1.4e-06 28.6 0.0 3.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC91369.1 - 6.9e-06 25.8 0.0 2.3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC91369.1 - 3.5e-05 24.3 0.0 0.00011 22.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMC91369.1 - 0.0017 17.7 0.0 0.0056 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMC91369.1 - 0.002 18.4 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC91369.1 - 0.0091 16.0 0.2 0.043 13.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC91369.1 - 0.0092 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AAA_16 PF13191.1 EMC91371.1 - 4e-13 49.7 2.4 2.8e-11 43.7 0.0 3.1 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC91371.1 - 9e-11 42.0 0.0 4.3e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EMC91371.1 - 1.9e-10 41.0 0.0 1.8e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC91371.1 - 5.1e-06 26.2 0.0 0.00019 21.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EMC91371.1 - 8.5e-06 25.4 0.1 0.0042 16.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EMC91371.1 - 0.00029 20.5 0.1 0.0012 18.5 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Cdc6_C PF09079.6 EMC91371.1 - 0.00049 19.7 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 CDC6, C terminal Mg_chelatase PF01078.16 EMC91371.1 - 0.0035 16.5 0.0 0.32 10.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EMC91371.1 - 0.0035 16.9 0.0 0.047 13.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain RNA12 PF10443.4 EMC91371.1 - 0.0039 15.7 0.0 0.0055 15.2 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein AFG1_ATPase PF03969.11 EMC91371.1 - 0.006 15.4 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase DUF815 PF05673.8 EMC91371.1 - 0.011 14.6 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMC91371.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMC91371.1 - 0.02 14.6 0.0 0.061 13.0 0.0 1.9 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 EMC91371.1 - 0.029 13.2 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EMC91371.1 - 0.032 13.9 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EMC91371.1 - 0.044 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMC91371.1 - 0.044 14.5 0.0 0.13 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC91371.1 - 0.05 13.7 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.9 EMC91371.1 - 0.054 12.4 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase KTI12 PF08433.5 EMC91371.1 - 0.069 12.3 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 EMC91371.1 - 0.069 12.6 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArgK PF03308.11 EMC91371.1 - 0.082 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein KAP_NTPase PF07693.9 EMC91371.1 - 0.1 11.5 0.1 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.4 EMC91371.1 - 0.1 11.5 0.0 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.1 EMC91371.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EMC91371.1 - 0.2 10.3 0.0 0.35 9.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF4271 PF14093.1 EMC91372.1 - 0.0045 16.6 1.3 0.0078 15.9 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4271) DUF202 PF02656.10 EMC91372.1 - 0.0053 16.9 0.2 2.2 8.5 0.0 2.6 1 1 0 2 2 2 1 Domain of unknown function (DUF202) Tetraspannin PF00335.15 EMC91372.1 - 0.0081 15.4 3.7 0.01 15.1 2.1 1.5 1 1 0 1 1 1 1 Tetraspanin family BCD PF15461.1 EMC91372.1 - 0.037 13.4 2.0 0.043 13.2 0.4 1.7 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase MscS_TM PF12794.2 EMC91372.1 - 0.068 11.7 2.0 0.11 11.1 1.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1772 PF08592.6 EMC91372.1 - 0.098 12.3 0.5 0.16 11.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3611 PF12263.3 EMC91372.1 - 0.57 9.5 5.7 1.8 7.9 1.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) MARVEL PF01284.18 EMC91372.1 - 0.89 9.3 8.2 2.3 8.0 4.9 2.3 1 1 0 1 1 1 0 Membrane-associating domain DUF3464 PF11947.3 EMC91372.1 - 1.3 8.4 4.0 43 3.5 2.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) DUF1218 PF06749.7 EMC91372.1 - 3.5 8.1 8.6 0.29 11.6 1.7 2.3 2 1 1 3 3 2 0 Protein of unknown function (DUF1218) ABC2_membrane_5 PF13346.1 EMC91372.1 - 5.6 6.1 9.1 0.3 10.3 2.4 1.7 2 1 0 2 2 2 0 ABC-2 family transporter protein Cys_knot PF00007.17 EMC91374.1 - 6.4 6.9 15.6 4.6 7.3 1.5 3.4 2 1 1 3 3 3 0 Cystine-knot domain E1_DerP2_DerF2 PF02221.10 EMC91376.1 - 0.0025 18.0 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 ML domain Enolase_C PF00113.17 EMC91377.1 - 2.4e-154 512.5 0.1 3.4e-154 512.1 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EMC91377.1 - 5.7e-58 194.5 0.5 9.1e-58 193.8 0.3 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EMC91377.1 - 0.0034 17.3 0.2 0.0079 16.1 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EMC91377.1 - 0.0056 15.6 1.4 0.026 13.4 0.2 2.2 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus DUF3356 PF11836.3 EMC91377.1 - 0.08 12.7 0.3 0.24 11.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) AAA PF00004.24 EMC91378.1 - 7.1e-43 145.9 0.0 1.2e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC91378.1 - 1.1e-07 31.9 0.1 3.5e-06 27.1 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EMC91378.1 - 1.9e-06 27.6 0.1 3.5e-05 23.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMC91378.1 - 2.1e-06 27.7 0.0 7.3e-06 25.9 0.0 1.9 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EMC91378.1 - 2.5e-06 27.6 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EMC91378.1 - 8.8e-06 24.9 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EMC91378.1 - 0.0003 19.8 0.0 0.00067 18.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EMC91378.1 - 0.00033 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMC91378.1 - 0.00074 20.3 0.6 0.0019 19.0 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EMC91378.1 - 0.0016 18.3 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMC91378.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EMC91378.1 - 0.0023 17.8 0.0 0.0064 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EMC91378.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMC91378.1 - 0.0031 16.7 0.0 0.0065 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EMC91378.1 - 0.0033 17.7 0.0 0.0093 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC91378.1 - 0.0054 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EMC91378.1 - 0.0061 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.6 EMC91378.1 - 0.0095 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMC91378.1 - 0.0096 15.3 0.1 0.046 13.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EMC91378.1 - 0.01 15.2 0.0 0.039 13.4 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF4200 PF13863.1 EMC91378.1 - 0.015 15.2 0.7 0.042 13.7 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_24 PF13479.1 EMC91378.1 - 0.02 14.5 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMC91378.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMC91378.1 - 0.025 13.6 0.0 0.098 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC ResIII PF04851.10 EMC91378.1 - 0.026 14.3 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 EMC91378.1 - 0.026 14.5 0.0 0.07 13.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EMC91378.1 - 0.032 13.4 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EMC91378.1 - 0.041 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EMC91378.1 - 0.044 13.4 0.0 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase UPF0079 PF02367.12 EMC91378.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EMC91378.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EMC91378.1 - 0.11 12.0 0.1 0.25 10.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EMC91378.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 COesterase PF00135.23 EMC91380.1 - 1.1e-71 242.2 0.5 3.6e-71 240.4 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC91380.1 - 1.1e-07 31.6 0.1 2.1e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1293 PF06950.6 EMC91380.1 - 0.045 13.6 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1293) Aminotran_5 PF00266.14 EMC91381.1 - 1.6e-27 96.2 0.0 2.8e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EMC91381.1 - 4.2e-23 81.3 0.0 8.3e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EMC91381.1 - 2.5e-18 65.8 0.0 5.4e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 MOSC domain SHR3_chaperone PF08229.6 EMC91382.1 - 8.6e-70 233.6 2.0 4.1e-69 231.4 1.4 1.9 1 1 0 1 1 1 1 ER membrane protein SH3 MFS_1 PF07690.11 EMC91382.1 - 0.26 9.9 3.3 0.11 11.2 0.6 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily LSM PF01423.17 EMC91383.1 - 1.1e-20 72.9 0.0 1.2e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 EMC91384.1 - 4.1e-16 58.9 0.0 4.9e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease PPTA PF01239.17 EMC91385.1 - 4.3e-41 136.5 20.1 4.7e-09 35.2 0.1 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 EMC91385.1 - 2.7 7.5 6.9 7.5 6.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) PALP PF00291.20 EMC91386.1 - 6.7e-61 206.1 1.3 8.1e-61 205.9 0.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 EMC91386.1 - 0.053 12.9 1.0 0.89 8.9 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Polyoma_coat2 PF00761.15 EMC91386.1 - 0.094 12.1 0.3 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein Proteasome PF00227.21 EMC91387.1 - 2.4e-40 137.8 0.0 2.9e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Diacid_rec PF05651.8 EMC91387.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative sugar diacid recognition OPT PF03169.10 EMC91390.1 - 1.2e-88 298.1 41.4 1.4e-88 297.9 28.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Prenyltrans PF00432.16 EMC91392.1 - 9.3e-29 98.6 19.8 6.5e-07 28.8 0.1 6.2 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMC91392.1 - 9.6e-20 71.0 0.0 2.1e-10 40.9 0.0 4.1 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC91392.1 - 0.00012 22.0 0.1 0.0034 17.3 0.0 2.4 1 1 1 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 EMC91392.1 - 0.028 13.6 0.0 2.2 7.4 0.0 2.2 1 1 2 3 3 3 0 A-macroglobulin complement component AA_permease PF00324.16 EMC91393.1 - 1.5e-146 488.5 34.4 1.7e-146 488.3 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMC91393.1 - 1.8e-42 145.3 35.7 2.5e-42 144.8 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.2 EMC91394.1 - 3.5e-07 29.8 0.1 9.3e-07 28.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC91394.1 - 0.0028 17.2 0.1 0.0054 16.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain AChE_tetra PF08674.5 EMC91394.1 - 9.9 5.7 7.4 1e+02 2.5 0.0 3.5 4 0 0 4 4 4 0 Acetylcholinesterase tetramerisation domain tRNA-synt_1g PF09334.6 EMC91395.1 - 1.5e-100 336.6 0.0 1e-99 333.8 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMC91395.1 - 5.4e-17 61.0 0.5 5.7e-10 37.8 0.0 3.8 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EMC91395.1 - 8.1e-05 21.8 0.0 0.025 13.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EMC91395.1 - 0.06 13.0 0.0 1.4 8.6 0.0 2.6 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA WW PF00397.21 EMC91396.1 - 9.2e-09 35.0 0.2 2.7e-08 33.5 0.2 1.9 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EMC91396.1 - 0.004 15.7 0.1 0.0074 14.8 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Peptidase_M48 PF01435.13 EMC91397.1 - 1.3e-46 158.9 0.0 1.8e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EMC91397.1 - 0.003 16.5 0.2 0.0086 15.0 0.1 1.5 1 1 0 1 1 1 1 BlaR1 peptidase M56 7TM_GPCR_Srj PF10319.4 EMC91398.1 - 0.081 12.0 0.1 0.084 11.9 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj zf-C2H2_3 PF13878.1 EMC91398.1 - 0.13 11.8 9.3 37 4.0 0.1 3.7 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Attractin PF08037.6 EMC91398.1 - 2.6 7.9 8.1 4 7.2 0.2 2.8 1 1 1 2 2 2 0 Attractin family Ribosomal_L34 PF00468.12 EMC91400.1 - 1.5e-17 62.9 12.5 2.4e-17 62.3 8.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Syja_N PF02383.13 EMC91401.1 - 1.1e-86 290.4 0.0 1.6e-86 289.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EMC91401.1 - 1.3e-21 77.6 0.0 4.7e-21 75.8 0.0 2.0 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family Ebola_NP PF05505.7 EMC91402.1 - 0.8 7.6 4.1 0.93 7.4 2.8 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein Sec10 PF07393.6 EMC91403.1 - 9.6e-145 483.5 0.0 1.8e-144 482.6 0.0 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EMC91403.1 - 6.2e-07 28.9 0.0 1.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC91403.1 - 2.4e-06 27.1 0.2 6.6e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like Phasin PF05597.6 EMC91403.1 - 0.058 13.1 3.7 0.85 9.3 0.0 3.4 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Abhydrolase_5 PF12695.2 EMC91404.1 - 9.3e-22 77.3 0.0 1.3e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC91404.1 - 3.8e-18 66.2 0.0 1.5e-16 60.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EMC91404.1 - 2e-06 26.5 0.1 0.066 11.6 0.1 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EMC91404.1 - 1.9e-05 24.3 0.0 0.00044 19.8 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMC91404.1 - 9.7e-05 21.9 0.0 0.1 12.0 0.0 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EMC91404.1 - 0.0002 20.9 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EMC91404.1 - 0.0005 19.8 0.0 0.017 14.7 0.0 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EMC91404.1 - 0.00077 18.7 0.0 0.0023 17.1 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EMC91404.1 - 0.0011 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.7 EMC91404.1 - 0.0014 17.4 0.1 0.002 16.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 EMC91404.1 - 0.0031 16.8 0.0 0.28 10.4 0.0 2.7 3 0 0 3 3 3 1 Dienelactone hydrolase family MCM PF00493.18 EMC91405.1 - 1.3e-131 438.3 0.0 3e-131 437.1 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EMC91405.1 - 9.2e-28 97.1 0.1 3.5e-27 95.2 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMC91405.1 - 1.3e-06 27.6 0.0 9.6e-05 21.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMC91405.1 - 5.2e-06 26.2 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EMC91405.1 - 0.056 12.9 0.0 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 EMC91405.1 - 0.086 12.4 0.1 0.34 10.5 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Oxidored_molyb PF00174.14 EMC91406.1 - 0.032 13.6 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain bZIP_1 PF00170.16 EMC91406.1 - 1.9 8.5 11.0 0.1 12.5 4.0 1.6 2 0 0 2 2 2 0 bZIP transcription factor Methyltransf_12 PF08242.7 EMC91408.1 - 2.5e-14 53.5 0.0 8e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC91408.1 - 1.4e-10 41.1 0.0 3.3e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC91408.1 - 6.5e-09 36.3 0.0 1.4e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC91408.1 - 5.7e-08 33.0 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC91408.1 - 6.2e-07 29.8 0.0 3.7e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC91408.1 - 3.2e-06 27.1 0.0 6.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMC91408.1 - 0.00011 21.2 0.0 0.02 13.8 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.1 EMC91408.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EMC91408.1 - 0.00082 20.1 0.0 0.0017 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC91408.1 - 0.0019 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EMC91408.1 - 0.053 12.5 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Polyketide_cyc PF03364.15 EMC91409.1 - 1.7e-18 66.8 0.0 2.6e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EMC91409.1 - 0.0029 17.7 0.0 0.04 14.1 0.0 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Phostensin PF13914.1 EMC91409.1 - 1.2 9.2 5.7 9.7 6.3 0.2 2.5 2 1 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region Bax1-I PF01027.15 EMC91410.1 - 4e-50 170.2 30.0 4.7e-50 170.0 20.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 EMC91410.1 - 0.08 11.9 1.2 0.51 9.2 0.2 2.3 2 0 0 2 2 2 0 Orbivirus NS3 Spore_YhaL PF14147.1 EMC91410.1 - 0.11 11.9 0.1 0.38 10.2 0.1 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL Herpes_UL43 PF05072.8 EMC91410.1 - 0.62 8.7 5.0 0.66 8.6 2.7 1.5 1 1 1 2 2 2 0 Herpesvirus UL43 protein DUF2910 PF11139.3 EMC91410.1 - 1.5 7.8 11.0 0.068 12.2 1.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2910) DUF2678 PF10856.3 EMC91410.1 - 1.8 8.3 6.1 0.3 10.8 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) TMEM141 PF15110.1 EMC91410.1 - 6.7 7.0 6.5 0.79 10.0 0.7 2.1 2 0 0 2 2 2 0 TMEM141 protein family Ecm29 PF13001.2 EMC91411.1 - 9.2e-128 426.8 0.0 2.5e-127 425.4 0.0 1.8 1 0 0 1 1 1 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.2 EMC91411.1 - 2.6e-05 24.5 0.0 0.0055 17.0 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EMC91411.1 - 5.4e-05 22.9 13.4 0.7 10.1 0.0 9.1 13 0 0 13 13 13 2 HEAT repeat Cnd1 PF12717.2 EMC91411.1 - 0.0084 15.9 0.0 38 4.0 0.0 4.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 V4R PF02830.13 EMC91411.1 - 0.051 13.4 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 V4R domain Fungal_trans_2 PF11951.3 EMC91412.1 - 8e-12 44.4 1.0 1.3e-11 43.7 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC91412.1 - 1.8e-06 27.7 10.3 3.7e-06 26.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain M20_dimer PF07687.9 EMC91413.1 - 3.4e-19 68.6 0.0 7.5e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EMC91413.1 - 6.9e-18 64.8 0.4 1.5e-17 63.7 0.3 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 R3H PF01424.17 EMC91414.1 - 7.9e-15 54.3 0.0 2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EMC91414.1 - 6.9e-06 25.8 31.8 9.2e-05 22.3 8.7 14.3 15 1 0 15 15 15 7 NF-X1 type zinc finger Pro_isomerase PF00160.16 EMC91415.1 - 5.4e-48 163.1 0.3 1.5e-47 161.6 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EMC91415.1 - 1.3e-09 37.5 0.6 0.013 15.3 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ADK PF00406.17 EMC91416.1 - 6.8e-46 155.8 0.0 9.5e-46 155.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EMC91416.1 - 3.3e-11 43.5 0.0 5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC91416.1 - 2.6e-07 31.4 0.0 3.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMC91416.1 - 8.3e-07 28.5 0.4 0.03 13.7 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EMC91416.1 - 5e-06 26.4 0.2 8.4e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC91416.1 - 0.046 12.8 1.2 0.18 10.8 0.8 1.8 1 1 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 EMC91416.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RhoGEF PF00621.15 EMC91419.1 - 6.2e-39 133.7 0.0 1.8e-38 132.2 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EMC91419.1 - 2.4e-20 73.0 0.1 2.4e-20 73.0 0.1 2.7 3 0 0 3 3 3 2 BAR domain Abhydrolase_3 PF07859.8 EMC91420.1 - 6.2e-16 58.6 0.0 6.8e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC91420.1 - 2.9e-09 36.8 0.0 3.2e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMC91420.1 - 2.3e-06 26.6 0.3 0.00012 20.9 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase PF07224.6 EMC91420.1 - 1.3e-05 24.1 0.0 1.3e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EMC91420.1 - 1.3e-05 24.2 0.0 1.3e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EMC91420.1 - 0.00059 19.7 0.0 0.0007 19.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC91420.1 - 0.0019 17.4 0.0 0.0081 15.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 EMC91420.1 - 0.018 14.6 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EMC91420.1 - 0.029 13.9 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.7 EMC91420.1 - 0.1 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AzlD PF05437.7 EMC91422.1 - 0.011 15.6 9.1 0.011 15.6 6.3 1.7 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Ilm1 PF10311.4 EMC91423.1 - 8.9e-48 161.9 0.9 1e-47 161.7 0.6 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Peptidase_M19 PF01244.16 EMC91424.1 - 5.1e-95 318.0 0.0 6e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ldh_1_C PF02866.13 EMC91425.1 - 0.051 13.3 2.4 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain AAA_24 PF13479.1 EMC91425.1 - 0.054 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain Evr1_Alr PF04777.8 EMC91425.1 - 0.14 12.1 1.8 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 Erv1 / Alr family Laminin_II PF06009.7 EMC91425.1 - 0.26 11.0 17.0 0.052 13.2 0.8 3.5 2 2 2 4 4 4 0 Laminin Domain II Reo_sigmaC PF04582.7 EMC91425.1 - 0.33 10.0 6.6 0.5 9.4 0.2 2.7 1 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF948 PF06103.6 EMC91425.1 - 1.1 9.1 10.3 8.8 6.2 0.3 4.1 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.6 EMC91425.1 - 1.3 8.4 32.0 0.12 11.8 5.0 4.3 2 2 3 5 5 5 0 Phage minor structural protein GP20 DUF3584 PF12128.3 EMC91425.1 - 3.2 4.9 36.4 0.034 11.5 8.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 EMC91425.1 - 6 7.2 21.0 3.1 8.1 1.9 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF972) DUF2563 PF10817.3 EMC91425.1 - 6.4 7.2 7.3 6.1 7.3 0.2 3.6 2 2 3 5 5 5 0 Protein of unknown function (DUF2563) DUF3287 PF11690.3 EMC91425.1 - 8.5 6.4 14.1 0.3 11.1 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) IncA PF04156.9 EMC91425.1 - 8.8 5.8 40.4 1.6 8.3 12.0 3.4 2 2 1 3 3 3 0 IncA protein MFS_1 PF07690.11 EMC91426.1 - 2e-48 164.9 36.0 2e-48 164.9 25.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC91426.1 - 3.3e-09 35.8 16.2 3.3e-09 35.8 11.2 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter PepSY_TM_2 PF13703.1 EMC91426.1 - 0.053 13.6 0.5 0.053 13.6 0.4 4.3 2 1 3 5 5 5 0 PepSY-associated TM helix GST_N_2 PF13409.1 EMC91429.1 - 9.2e-07 28.7 0.1 2.8e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMC91429.1 - 5.4e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC91429.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC91429.1 - 0.00021 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC91429.1 - 0.0039 17.3 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RNA_pol_L_2 PF13656.1 EMC91430.1 - 9.7e-24 82.6 0.0 1.5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMC91430.1 - 6.1e-12 44.4 0.0 3.8e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3666 PF12408.3 EMC91430.1 - 0.095 11.8 0.1 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Dermcidin PF15291.1 EMC91433.1 - 0.072 13.2 1.8 0.18 11.9 1.2 1.7 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Alpha-amylase PF00128.19 EMC91434.1 - 8.6e-31 107.4 0.0 1.8e-30 106.4 0.0 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Sugar_tr PF00083.19 EMC91435.1 - 2.1e-80 270.5 23.7 2.5e-80 270.2 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC91435.1 - 5.9e-17 61.4 41.2 2.9e-11 42.7 14.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC91435.1 - 9.8e-08 30.7 25.3 0.00039 18.9 2.2 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein Coatomer_E PF04733.9 EMC91435.1 - 0.018 14.2 0.2 0.042 13.0 0.0 1.6 2 0 0 2 2 2 0 Coatomer epsilon subunit Fungal_trans PF04082.13 EMC91436.1 - 2.2e-09 36.5 0.5 3.3e-09 36.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC91436.1 - 4.1e-08 33.0 10.3 6.2e-08 32.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.7 EMC91436.1 - 0.35 9.1 1.9 0.55 8.5 1.3 1.2 1 0 0 1 1 1 0 Per os infectivity G_glu_transpept PF01019.16 EMC91437.1 - 2.1e-156 521.3 0.2 2.4e-156 521.1 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ABC_tran PF00005.22 EMC91438.1 - 1.8e-49 167.5 0.2 2e-28 99.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMC91438.1 - 2.4e-29 102.5 19.1 1e-28 100.5 7.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.1 EMC91438.1 - 6.2e-10 39.3 2.1 8e-06 25.9 0.6 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EMC91438.1 - 3.8e-08 33.6 2.6 0.3 11.0 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EMC91438.1 - 1.1e-05 24.8 2.7 0.032 13.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EMC91438.1 - 1.2e-05 24.7 7.7 0.018 14.3 0.1 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EMC91438.1 - 2e-05 23.8 0.2 0.04 13.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMC91438.1 - 2.4e-05 24.4 0.3 0.048 13.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EMC91438.1 - 2.6e-05 23.8 0.3 0.23 10.9 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 EMC91438.1 - 0.00044 19.6 0.9 0.45 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EMC91438.1 - 0.00044 19.7 0.5 0.91 8.8 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 EMC91438.1 - 0.00073 20.0 0.2 0.22 12.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EMC91438.1 - 0.0016 17.3 0.1 0.58 9.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 EMC91438.1 - 0.0023 18.2 0.2 0.4 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EMC91438.1 - 0.0037 16.7 0.2 0.47 9.9 0.0 3.1 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 EMC91438.1 - 0.0039 17.1 0.0 0.73 9.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EMC91438.1 - 0.0056 16.5 0.0 3.4 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EMC91438.1 - 0.0063 15.9 0.5 2.2 7.6 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EMC91438.1 - 0.014 15.0 0.2 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EMC91438.1 - 0.025 14.1 3.0 0.47 9.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EMC91438.1 - 0.045 13.4 2.5 2 8.0 0.1 2.9 3 0 0 3 3 2 0 NACHT domain Zeta_toxin PF06414.7 EMC91438.1 - 0.068 12.2 0.7 11 5.0 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EMC91438.1 - 0.11 13.3 0.2 3.9 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMC91438.1 - 0.11 12.1 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EMC91438.1 - 0.11 12.3 0.0 10 6.0 0.0 3.1 4 0 0 4 4 3 0 AAA domain SbcCD_C PF13558.1 EMC91438.1 - 0.16 11.9 1.3 34 4.4 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EMC91438.1 - 0.16 11.6 1.2 3 7.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EMC91438.1 - 0.17 10.7 0.3 6.6 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EMC91438.1 - 0.9 9.3 2.8 13 5.5 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Sod_Fe_C PF02777.13 EMC91439.1 - 7.2e-11 41.8 0.0 0.00029 20.6 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMC91439.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Cnd2 PF05786.9 EMC91440.1 - 2.8e-199 664.2 0.7 3.2e-199 664.0 0.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 EMC91441.1 - 2.6e-46 156.7 36.5 3.3e-25 88.3 9.8 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4267 PF14087.1 EMC91442.1 - 1.2e-15 57.0 3.7 1.5e-15 56.7 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) UPF0233 PF06781.7 EMC91442.1 - 0.019 14.5 0.7 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) G-patch PF01585.18 EMC91443.1 - 6.4e-05 22.6 0.0 0.00049 19.8 0.0 2.5 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC91443.1 - 0.045 13.6 0.0 0.045 13.6 0.0 3.0 3 0 0 3 3 3 0 DExH-box splicing factor binding site SOBP PF15279.1 EMC91443.1 - 1.3 9.3 11.9 1.8 8.9 8.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.9 EMC91443.1 - 1.5 6.7 16.7 2 6.3 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Acetyltransf_3 PF13302.1 EMC91444.1 - 1.4e-21 77.1 0.0 1.9e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMC91444.1 - 1.5e-13 50.9 0.0 5.3e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC91444.1 - 4.8e-13 48.9 0.1 7.6e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMC91444.1 - 7.9e-11 42.0 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC91444.1 - 3.7e-05 23.7 0.1 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC91444.1 - 0.00061 19.4 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Glyco_hydro_10 PF00331.15 EMC91445.1 - 4.4e-79 265.8 2.1 5.3e-79 265.5 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4454 PF14628.1 EMC91445.1 - 0.099 12.2 0.2 0.21 11.1 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4454) GST_N_3 PF13417.1 EMC91446.1 - 5.2e-19 68.2 0.0 1.1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC91446.1 - 4.5e-12 45.7 0.0 9.6e-11 41.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC91446.1 - 8.2e-12 45.1 0.0 4.2e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC91446.1 - 3.3e-09 36.6 0.0 6.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC91446.1 - 1.5e-08 34.3 0.0 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC91446.1 - 1.4e-06 28.7 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF221 PF02714.10 EMC91447.1 - 8.4e-97 323.9 16.0 8.4e-97 323.9 11.1 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMC91447.1 - 8.8e-39 132.5 2.2 8.8e-39 132.5 1.6 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMC91447.1 - 6.8e-19 67.5 0.1 1.5e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EMC91447.1 - 1.2e-07 32.1 0.0 2.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) E1-E2_ATPase PF00122.15 EMC91448.1 - 2.5e-67 226.2 6.8 5.6e-66 221.8 3.2 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC91448.1 - 7.1e-47 159.2 6.0 7.1e-47 159.2 4.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMC91448.1 - 2.1e-31 109.9 0.0 1.9e-30 106.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC91448.1 - 1.2e-21 76.5 0.0 2.4e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMC91448.1 - 9.6e-17 60.2 0.0 2.4e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC91448.1 - 6.5e-16 59.0 0.1 2.6e-15 57.1 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC91448.1 - 2e-08 34.1 1.7 3e-06 27.0 0.6 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC91448.1 - 0.028 14.6 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 EMC91448.1 - 0.11 12.0 6.0 0.043 13.3 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) TFIIA PF03153.8 EMC91450.1 - 4.2 7.1 9.9 1.7 8.4 5.1 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rad60-SLD PF11976.3 EMC91451.1 - 0.019 14.6 0.0 3.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like RHH_1 PF01402.16 EMC91451.1 - 0.058 13.2 0.3 0.47 10.4 0.3 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family 14-3-3 PF00244.15 EMC91452.1 - 1.2e-114 381.2 0.4 1.4e-114 381.0 0.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EMC91452.1 - 0.048 13.5 0.9 6.1 6.8 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4085 PF13315.1 EMC91452.1 - 0.074 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HisKA PF00512.20 EMC91452.1 - 0.12 12.3 1.1 11 6.0 0.0 3.2 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain MFS_1 PF07690.11 EMC91453.1 - 5e-38 130.7 52.9 5e-38 130.7 36.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC91453.1 - 1.4e-05 23.8 16.6 1.4e-05 23.8 11.5 4.2 3 2 1 4 4 4 1 Sugar (and other) transporter WTF PF03303.8 EMC91453.1 - 0.25 10.7 7.3 0.066 12.6 2.3 2.1 3 0 0 3 3 3 0 WTF protein DEAD PF00270.24 EMC91455.1 - 5.5e-39 133.3 0.0 3.2e-38 130.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC91455.1 - 4.9e-26 90.3 0.1 1.1e-25 89.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dscam_C PF12355.3 EMC91455.1 - 0.014 15.6 0.5 0.014 15.6 0.3 4.1 3 2 0 4 4 4 0 Down syndrome cell adhesion molecule C terminal DUF3334 PF11813.3 EMC91455.1 - 0.17 11.4 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) FAM74 PF15026.1 EMC91455.1 - 0.31 10.6 3.7 0.21 11.2 0.7 2.1 2 0 0 2 2 2 0 FAM74 protein Rad60-SLD PF11976.3 EMC91456.1 - 0.0035 16.9 0.0 0.035 13.7 0.0 2.6 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like DUF1640 PF07798.6 EMC91457.1 - 5.9e-65 218.6 6.1 7e-65 218.3 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) His_kinase PF06580.8 EMC91457.1 - 0.69 9.8 2.8 0.82 9.6 0.0 2.3 3 0 0 3 3 3 0 Histidine kinase DUF4600 PF15372.1 EMC91457.1 - 1.6 8.9 9.0 2.1 8.5 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DUF3602 PF12223.3 EMC91458.1 - 3e-18 65.9 8.7 8.4e-18 64.5 1.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) GHMP_kinases_N PF00288.21 EMC91459.1 - 2e-16 59.8 0.2 7.3e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMC91459.1 - 2.4e-09 37.2 0.1 6.6e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EMC91459.1 - 0.1 11.9 0.1 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Prenyltrans PF00432.16 EMC91461.1 - 3.5e-62 205.5 12.7 1.9e-12 46.4 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMC91461.1 - 1.2e-39 135.2 0.0 1.4e-12 48.0 0.0 3.8 1 1 4 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC91461.1 - 1.5e-08 34.6 0.0 8.4e-06 25.7 0.0 3.1 2 1 1 3 3 3 2 Prenyltransferase-like RhoGAP PF00620.22 EMC91462.1 - 1.2e-28 99.6 0.0 1.9e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Nucleo_P87 PF07267.6 EMC91462.1 - 6.1 5.3 10.9 8.6 4.9 7.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SnoaL_2 PF12680.2 EMC91463.1 - 3.3e-06 27.4 0.2 1.7e-05 25.1 0.1 1.8 1 1 1 2 2 2 1 SnoaL-like domain SnoaL PF07366.7 EMC91463.1 - 0.0047 16.5 0.1 0.027 14.0 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase tRNA-synt_2b PF00587.20 EMC91463.1 - 0.067 12.7 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) ADH_zinc_N PF00107.21 EMC91465.1 - 1.6e-24 85.9 2.4 5.3e-24 84.2 0.2 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC91465.1 - 7.3e-14 51.4 3.1 1.4e-13 50.5 2.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EMC91465.1 - 0.0064 17.0 0.2 0.012 16.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMC91465.1 - 0.02 14.6 0.1 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Pam17 PF08566.5 EMC91467.1 - 8e-54 181.9 0.0 9.1e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 UCR_Fe-S_N PF10399.4 EMC91467.1 - 0.014 14.5 0.2 0.014 14.5 0.1 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Patatin PF01734.17 EMC91470.1 - 3.8e-23 82.4 0.0 6.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.11 EMC91471.1 - 1.2e-31 109.7 29.1 2e-31 108.9 20.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SIS PF01380.17 EMC91474.1 - 1.5e-53 179.9 0.1 4.2e-29 100.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EMC91474.1 - 7.5e-27 93.9 0.0 7e-18 64.4 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMC91474.1 - 4.4e-20 72.0 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMC91474.1 - 9.7e-13 47.9 0.0 2.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EMC91474.1 - 9.1e-07 27.8 0.0 1.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EMC91474.1 - 0.033 13.9 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 SIS domain CFEM PF05730.6 EMC91475.1 - 6.5e-10 38.6 11.7 6.5e-10 38.6 8.1 2.4 2 1 0 2 2 2 1 CFEM domain CDC27 PF09507.5 EMC91475.1 - 0.031 13.5 1.8 0.038 13.2 1.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF966 PF06136.8 EMC91475.1 - 0.14 11.5 1.5 0.18 11.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Lactamase_B_2 PF12706.2 EMC91476.1 - 3.8e-23 82.0 0.0 5.9e-23 81.4 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC91476.1 - 1.2e-12 47.8 0.5 2.5e-12 46.8 0.3 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC91476.1 - 0.00038 20.1 7.3 0.049 13.2 2.7 3.1 2 1 1 3 3 3 2 Metallo-beta-lactamase superfamily Ribosomal_L38e PF01781.13 EMC91477.1 - 7.1e-33 112.1 2.3 9.4e-33 111.7 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Mtr2 PF10429.4 EMC91478.1 - 0.00012 21.9 0.0 0.00042 20.1 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.15 EMC91478.1 - 0.0003 21.1 0.2 0.0017 18.6 0.1 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain AAA_23 PF13476.1 EMC91479.1 - 0.21 11.9 3.2 0.36 11.1 2.2 1.4 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EMC91479.1 - 0.31 9.9 8.6 0.5 9.2 5.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ish1 PF10281.4 EMC91480.1 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein Glyco_hydro_47 PF01532.15 EMC91481.1 - 8.2e-162 538.9 0.5 1.1e-161 538.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PTH2 PF01981.11 EMC91482.1 - 0.12 12.0 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Ferritin_2 PF13668.1 EMC91483.1 - 7.6e-06 25.9 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ferritin-like domain HET PF06985.6 EMC91485.1 - 6e-25 88.0 1.5 9.6e-25 87.3 1.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Proteasome PF00227.21 EMC91486.1 - 1.1e-27 96.5 0.1 2.6e-27 95.3 0.1 1.6 1 1 1 2 2 2 1 Proteasome subunit MDM31_MDM32 PF08118.6 EMC91487.1 - 5.9e-187 622.1 0.2 6.8e-187 621.9 0.1 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 EMC91488.1 - 3e-05 23.5 0.5 6.8e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 KH domain Abhydrolase_5 PF12695.2 EMC91490.1 - 2.7e-14 53.1 0.1 4.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC91490.1 - 4e-06 26.8 0.5 0.017 15.0 0.3 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC91490.1 - 0.045 13.3 0.1 0.073 12.6 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ubie_methyltran PF01209.13 EMC91491.1 - 0.00023 20.3 0.0 0.0044 16.1 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EMC91491.1 - 0.0003 20.5 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PepSY_2 PF13670.1 EMC91491.1 - 0.01 15.7 0.1 0.069 13.0 0.0 2.1 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain Methyltransf_11 PF08241.7 EMC91491.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMC91491.1 - 0.025 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_28 PF00295.12 EMC91492.1 - 7.7e-39 133.5 1.6 1e-37 129.8 1.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Toxin_6 PF05453.7 EMC91494.1 - 0.097 12.9 3.4 0.22 11.8 2.3 1.6 1 0 0 1 1 1 0 BmTXKS1/BmP02 toxin family SOG2 PF10428.4 EMC91494.1 - 0.14 10.7 4.8 0.15 10.6 3.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Binary_toxB PF03495.9 EMC91494.1 - 3.2 6.2 8.7 3.9 5.9 6.0 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA NAD_synthase PF02540.12 EMC91495.1 - 6.3e-24 84.2 0.0 2.3e-23 82.3 0.0 1.8 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EMC91495.1 - 7.6e-18 64.5 0.0 1.4e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CPSase_L_D2 PF02786.12 EMC91496.1 - 2e-81 272.3 0.0 3e-81 271.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EMC91496.1 - 1.9e-67 226.5 0.0 2.9e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EMC91496.1 - 4.7e-34 116.7 0.0 1.1e-33 115.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMC91496.1 - 4.5e-30 103.7 0.0 1.2e-29 102.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EMC91496.1 - 9.2e-28 97.4 0.0 2.2e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EMC91496.1 - 1.5e-18 67.2 0.1 2.6e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EMC91496.1 - 1.1e-17 63.4 5.6 1.3e-17 63.1 2.8 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EMC91496.1 - 3.5e-13 48.9 0.0 3.2e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMC91496.1 - 3.3e-11 42.9 0.0 6.7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EMC91496.1 - 4.4e-10 39.0 1.9 1.9e-07 30.6 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EMC91496.1 - 2e-06 27.2 0.0 4.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EMC91496.1 - 1.8e-05 24.9 0.3 0.00052 20.3 0.2 3.1 2 1 1 3 3 3 1 HlyD family secretion protein ATP-grasp_3 PF02655.9 EMC91496.1 - 3.3e-05 23.7 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EMC91496.1 - 6.1e-05 22.3 0.4 0.14 11.2 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 EMC91496.1 - 6.9e-05 22.4 0.0 0.00041 19.8 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD PF00529.15 EMC91496.1 - 0.0048 16.2 0.5 0.036 13.3 0.1 2.3 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EMC91496.1 - 0.0098 15.4 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 EMC91496.1 - 0.21 11.2 1.0 0.8 9.4 0.4 2.1 1 1 1 2 2 2 0 Glycine cleavage H-protein CMAS PF02353.15 EMC91497.1 - 2.3e-61 207.2 0.1 2.8e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EMC91497.1 - 3.5e-14 52.8 0.0 6.8e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC91497.1 - 7.1e-08 32.8 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC91497.1 - 0.0005 20.6 0.0 0.0051 17.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC91497.1 - 0.00086 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC91497.1 - 0.0014 18.5 0.0 0.0045 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC91497.1 - 0.0055 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC91497.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EMC91497.1 - 0.033 13.5 0.1 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EMC91497.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EMC91497.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 WD40 PF00400.27 EMC91498.1 - 4.3e-86 280.0 18.5 5e-15 54.7 0.3 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EMC91498.1 - 2.7e-07 29.1 3.4 0.0065 14.6 0.0 3.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EMC91498.1 - 3.6e-06 26.8 0.0 0.032 13.9 0.0 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 EMC91498.1 - 0.00038 20.4 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain TFIIIC_delta PF12657.2 EMC91498.1 - 0.0039 16.9 0.4 5.3 6.7 0.0 3.8 3 1 0 4 4 4 1 Transcription factor IIIC subunit delta N-term Nbas_N PF15492.1 EMC91498.1 - 0.038 13.0 0.1 8.3 5.4 0.0 3.3 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF1652 PF07865.6 EMC91498.1 - 0.15 11.6 0.0 2.1 7.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) MutS_V PF00488.16 EMC91499.1 - 2.9e-78 262.4 0.5 4.5e-78 261.9 0.4 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC91499.1 - 4.6e-32 111.4 5.0 1.3e-31 110.0 3.5 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EMC91499.1 - 4.4e-11 43.0 0.2 1.7e-10 41.0 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EMC91499.1 - 3.4e-09 36.7 0.3 3.4e-09 36.7 0.2 2.3 2 1 0 2 2 2 1 MutS family domain IV Y_phosphatase3 PF13350.1 EMC91500.1 - 4.6e-31 108.2 0.0 3.8e-30 105.3 0.0 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EMC91500.1 - 1.2e-09 37.7 0.1 6.2e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EMC91500.1 - 5.3e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EMC91500.1 - 0.0002 20.7 0.0 0.00065 19.0 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC91500.1 - 0.00025 20.6 0.0 0.0028 17.2 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EMC91500.1 - 0.015 14.1 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF3812 PF12757.2 EMC91501.1 - 2.2e-38 131.0 18.7 2.2e-38 131.0 13.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF3812) DNA_pol3_a_NII PF11490.3 EMC91501.1 - 2.6 7.6 8.5 10 5.7 5.9 2.0 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PCI PF01399.22 EMC91502.1 - 1.7e-14 53.9 0.3 4.3e-14 52.6 0.1 1.8 2 0 0 2 2 2 1 PCI domain REV PF00424.13 EMC91502.1 - 0.03 14.1 1.5 0.03 14.1 1.0 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DNA_pol_E_B PF04042.11 EMC91503.1 - 2.7e-48 163.9 0.0 3.8e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Zw10 PF06248.8 EMC91504.1 - 7.3e-09 34.3 0.0 1.5e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EMC91504.1 - 3e-08 33.1 0.0 1.8e-06 27.3 0.1 2.6 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Tropomyosin_1 PF12718.2 EMC91504.1 - 0.00094 19.0 3.9 0.00094 19.0 2.7 3.0 2 1 1 3 3 3 1 Tropomyosin like Hrs_helical PF12210.3 EMC91504.1 - 0.0077 16.4 3.1 3.8 7.8 0.0 3.2 2 1 1 3 3 3 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Syntaxin-6_N PF09177.6 EMC91504.1 - 0.16 12.3 0.1 0.16 12.3 0.0 3.9 3 1 1 5 5 5 0 Syntaxin 6, N-terminal Acetyltransf_1 PF00583.19 EMC91505.1 - 3.5e-08 33.3 0.0 6.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC91505.1 - 4.2e-06 26.8 0.0 7.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC91505.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC91505.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EMC91505.1 - 0.0021 17.9 0.0 0.0089 15.8 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain HMGL-like PF00682.14 EMC91506.1 - 8.7e-70 235.0 2.4 1.5e-69 234.2 1.6 1.4 1 0 0 1 1 1 1 HMGL-like PGA_cap PF09587.5 EMC91506.1 - 0.088 12.1 2.8 4.9 6.4 0.0 2.6 2 1 1 3 3 3 0 Bacterial capsule synthesis protein PGA_cap MPC PF03650.8 EMC91507.1 - 4.4e-23 81.5 0.0 5.3e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF883 PF05957.8 EMC91507.1 - 0.05 13.9 0.8 0.07 13.5 0.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Transpep_BrtH PF14399.1 EMC91507.1 - 0.074 12.3 0.1 0.079 12.2 0.1 1.1 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase ATP-synt_B PF00430.13 EMC91507.1 - 0.13 12.0 1.6 0.18 11.6 1.1 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CAP PF00188.21 EMC91508.1 - 1.8e-07 31.7 0.6 2.6e-07 31.1 0.4 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mucin PF01456.12 EMC91508.1 - 0.27 10.9 18.6 0.34 10.6 12.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_L5_C PF00673.16 EMC91509.1 - 4.5e-22 77.6 0.0 6.2e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMC91509.1 - 4.1e-20 71.3 0.1 9.8e-20 70.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EMC91510.1 - 4.5e-16 58.1 0.0 6.9e-16 57.5 0.0 1.3 1 1 0 1 1 1 1 LSM domain CMD PF02627.15 EMC91511.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family SWIB PF02201.13 EMC91512.1 - 8.9e-26 89.3 0.1 1.4e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EMC91512.1 - 3.1e-14 52.4 0.5 3.1e-14 52.4 0.4 1.8 2 0 0 2 2 2 1 DEK C terminal domain MFS_1 PF07690.11 EMC91513.1 - 5.7e-19 68.0 54.8 1.5e-17 63.4 31.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PAF-AH_p_II PF03403.8 EMC91514.1 - 1.6e-33 115.5 0.0 2.3e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMC91514.1 - 1.1e-09 38.1 0.0 2.7e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMC91514.1 - 0.0019 17.1 0.0 0.43 9.4 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EMC91514.1 - 0.0024 17.7 0.0 0.0072 16.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMC91514.1 - 0.097 12.2 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold PAT1 PF09770.4 EMC91517.1 - 1.8e-237 790.5 13.1 2.1e-237 790.3 9.1 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 EMC91518.1 - 5.7e-141 469.2 11.8 7.4e-141 468.8 8.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.2 EMC91518.1 - 0.28 11.1 2.2 0.54 10.2 1.5 1.5 1 0 0 1 1 1 0 EGF domain F-box PF00646.28 EMC91520.1 - 2.8e-07 30.0 0.4 2.6e-06 26.9 0.2 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMC91520.1 - 0.0048 16.6 0.1 0.014 15.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Spc97_Spc98 PF04130.8 EMC91522.1 - 9.6e-65 218.9 0.0 1.2e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Mito_carr PF00153.22 EMC91523.1 - 1.7e-67 223.1 7.3 5.5e-24 83.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EMC91523.1 - 2.3e-22 78.8 2.9 1.8e-10 40.7 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC91523.1 - 2.8e-21 73.1 0.4 5.6e-05 22.1 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 EMC91523.1 - 2e-15 55.3 6.5 0.00013 21.1 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC91523.1 - 3.7e-15 54.3 4.4 0.00068 19.3 0.5 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EMC91523.1 - 7.6e-12 44.6 2.6 0.00015 21.3 0.1 3.4 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC91523.1 - 6.9e-10 38.9 0.1 0.001 19.0 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC91523.1 - 0.00056 19.5 1.8 0.77 9.5 0.2 3.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EMC91523.1 - 0.0018 17.8 1.6 2.5 7.8 0.1 3.5 3 1 0 3 3 3 2 EF hand NDUF_B12 PF08122.7 EMC91523.1 - 0.094 12.4 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Response_reg PF00072.19 EMC91524.1 - 7.2e-22 77.5 0.9 2.4e-21 75.8 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EMC91524.1 - 2e-20 72.5 0.0 3.6e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMC91524.1 - 1.6e-09 37.5 0.8 4.7e-09 36.1 0.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EMC91524.1 - 6.6e-09 36.0 0.0 2.9e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 EMC91524.1 - 1e-06 28.7 0.0 2.8e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EMC91524.1 - 0.0002 21.0 0.0 0.0007 19.3 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EMC91524.1 - 0.002 18.1 0.0 0.54 10.3 0.0 3.2 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EMC91524.1 - 0.0023 17.7 0.0 0.0062 16.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.1 EMC91524.1 - 0.02 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3112 PF11309.3 EMC91525.1 - 2e-36 125.2 15.7 7e-34 116.9 5.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Renin_r PF07850.9 EMC91525.1 - 6.7 7.1 5.7 4.8 7.5 2.1 2.1 1 1 1 2 2 2 0 Renin receptor-like protein zf-ZPR1 PF03367.8 EMC91527.1 - 5.9e-104 344.1 0.1 1.7e-52 176.8 0.0 2.7 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EMC91527.1 - 0.52 10.0 3.2 11 5.6 0.3 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EMC91527.1 - 1.6 8.7 8.3 7.6 6.5 0.0 4.0 4 0 0 4 4 4 0 Zinc ribbon domain Rpr2 PF04032.11 EMC91528.1 - 4.8e-09 35.9 0.6 9.7e-09 34.9 0.4 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 EMC91528.1 - 0.095 12.5 2.2 0.22 11.3 1.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF4451 PF14616.1 EMC91528.1 - 0.15 11.7 0.8 9.8 5.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) tRNA_int_end_N2 PF12928.2 EMC91529.1 - 4e-22 77.4 0.0 7.8e-22 76.5 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EMC91529.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain DBR1 PF05011.8 EMC91530.1 - 4.4e-40 136.9 0.0 7.7e-40 136.1 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EMC91530.1 - 0.00041 19.8 0.1 0.00079 18.8 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DehI PF10778.4 EMC91531.1 - 0.076 12.5 0.0 0.092 12.2 0.0 1.1 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI HET PF06985.6 EMC91533.1 - 1.7e-11 44.4 1.1 1.2e-08 35.1 0.0 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Toxin_18 PF08087.6 EMC91533.1 - 0.1 12.3 0.9 0.18 11.6 0.6 1.3 1 0 0 1 1 1 0 Conotoxin O-superfamily TPR_12 PF13424.1 EMC91534.1 - 4.7e-11 42.4 5.6 0.48 10.4 0.0 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC91534.1 - 1.3e-09 37.8 19.6 0.059 14.0 0.0 10.5 10 2 2 12 12 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC91534.1 - 6.6e-09 35.9 0.3 0.08 13.2 0.0 6.0 4 1 1 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 EMC91534.1 - 1.8e-08 34.4 8.4 0.27 10.9 0.1 5.9 4 2 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EMC91534.1 - 3.7e-07 29.7 6.5 0.65 9.6 0.0 7.0 8 0 0 8 8 8 2 TPR repeat TPR_8 PF13181.1 EMC91534.1 - 2.5e-06 26.8 0.3 1.2 9.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC91534.1 - 4.4e-05 24.0 8.3 0.89 10.3 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC91534.1 - 0.00011 21.8 9.5 0.15 12.0 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC91534.1 - 0.002 18.2 4.0 2.3 8.6 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC91534.1 - 0.003 17.2 10.5 0.7 9.8 0.0 7.1 9 0 0 9 9 9 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EMC91534.1 - 0.035 13.8 14.5 5.6 6.7 0.0 6.8 6 3 3 9 9 9 0 Mad3/BUB1 homology region 1 SHNi-TPR PF10516.4 EMC91534.1 - 0.051 12.8 0.6 0.9 8.8 0.0 3.1 3 0 0 3 3 3 0 SHNi-TPR Complex1_LYR_2 PF13233.1 EMC91534.1 - 0.25 11.8 3.2 30 5.1 0.0 3.3 2 1 0 2 2 2 0 Complex1_LYR-like TPR_10 PF13374.1 EMC91534.1 - 0.26 11.2 0.0 0.26 11.2 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Pantoate_ligase PF02569.10 EMC91535.1 - 3.9e-82 275.1 0.0 6.6e-82 274.4 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Sugar_tr PF00083.19 EMC91537.1 - 1.4e-84 284.3 23.6 1.6e-84 284.1 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC91537.1 - 8.3e-22 77.3 41.0 1.1e-15 57.2 12.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMC91537.1 - 0.0039 17.1 3.7 1.8 8.6 0.4 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1228) OATP PF03137.15 EMC91537.1 - 0.049 11.6 11.9 0.33 8.9 0.0 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EMC91538.1 - 3.4e-94 315.9 23.5 4.2e-94 315.6 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC91538.1 - 1.8e-25 89.4 24.6 8.8e-25 87.1 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NaeI PF09126.5 EMC91538.1 - 0.0005 18.8 0.0 0.00071 18.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease NaeI Glyco_hydro_72 PF03198.9 EMC91539.1 - 8.4e-110 366.6 0.5 1.1e-109 366.3 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EMC91539.1 - 0.018 14.2 0.0 1 8.4 0.0 2.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Hamartin PF04388.7 EMC91540.1 - 1.1e-41 143.3 0.9 2.1e-41 142.3 0.6 1.5 1 1 0 1 1 1 1 Hamartin protein Ribonuclease_3 PF00636.21 EMC91542.1 - 7.2e-41 139.2 0.0 7.4e-20 71.5 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMC91542.1 - 1e-23 83.7 0.0 1.5e-11 44.3 0.0 3.2 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EMC91542.1 - 7.4e-21 73.7 0.3 2.6e-20 71.9 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 EMC91542.1 - 6.5e-15 54.7 0.0 1.7e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC91542.1 - 2.3e-13 49.9 0.0 8.3e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMC91542.1 - 1.9e-11 44.1 0.0 4.8e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMC91542.1 - 9.3e-05 21.3 0.9 0.0019 17.0 0.1 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EMC91542.1 - 0.12 12.4 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain TAP42 PF04177.7 EMC91543.1 - 1.1e-101 340.1 2.0 1.3e-101 339.9 1.4 1.0 1 0 0 1 1 1 1 TAP42-like family PAPS_reduct PF01507.14 EMC91544.1 - 6.1e-28 97.8 0.0 3.5e-19 69.2 0.0 2.6 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.20 EMC91545.1 - 1.8e-23 83.0 0.0 2.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EMC91545.1 - 1.8e-12 46.5 5.7 7.7e-08 31.9 0.5 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.17 EMC91545.1 - 8.2e-07 28.6 7.8 0.018 15.0 0.1 6.4 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.12 EMC91545.1 - 2.8e-05 23.3 0.0 4.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC91545.1 - 3.8e-05 22.8 0.0 7.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.1 EMC91545.1 - 0.0085 16.3 4.6 0.04 14.1 0.0 3.9 3 1 1 4 4 4 1 HEAT repeats Citrate_synt PF00285.16 EMC91547.1 - 2e-19 69.5 0.0 4.8e-16 58.4 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EMC91547.1 - 1.1e-12 48.2 0.0 4.4e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 EMC91547.1 - 0.0049 16.4 0.4 0.094 12.3 0.1 2.3 1 1 1 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 EMC91547.1 - 0.025 14.1 0.5 1.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EMC91549.1 - 3.3e-08 33.1 0.0 5.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain 3HCDH_N PF02737.13 EMC91550.1 - 1.1e-34 119.6 0.0 1.5e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMC91550.1 - 6.4e-19 68.1 0.0 1.4e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EMC91550.1 - 2.8e-05 23.8 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EMC91550.1 - 0.0075 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMC91550.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMC91550.1 - 0.015 14.4 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SGL PF08450.7 EMC91550.1 - 0.017 14.5 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region UDPG_MGDP_dh_N PF03721.9 EMC91550.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldl_recept_b PF00058.12 EMC91550.1 - 0.028 14.7 0.6 4.9 7.5 0.1 3.7 3 1 0 3 3 3 0 Low-density lipoprotein receptor repeat class B NAD_binding_7 PF13241.1 EMC91550.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_1 PF00175.16 EMC91551.1 - 2.9e-28 98.5 0.0 5.5e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMC91551.1 - 2.6e-25 88.4 0.0 4.6e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EMC91551.1 - 5.9e-20 70.8 0.1 1.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EMC91551.1 - 1.3e-05 25.1 0.0 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMC91551.1 - 4.9e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain p450 PF00067.17 EMC91552.1 - 5.9e-70 236.0 0.0 7.3e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PduL PF06130.7 EMC91552.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Propanediol utilisation protein PduL FYVE PF01363.16 EMC91553.1 - 0.0024 17.7 14.2 0.033 14.0 2.0 2.6 2 0 0 2 2 2 2 FYVE zinc finger zf-C3HC4 PF00097.20 EMC91553.1 - 0.036 13.7 19.7 0.17 11.5 2.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tnp_zf-ribbon_2 PF13842.1 EMC91553.1 - 0.18 12.2 0.1 0.18 12.2 0.1 4.2 3 1 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Siva PF05458.7 EMC91553.1 - 0.37 10.3 19.9 0.35 10.4 1.5 2.6 3 0 0 3 3 3 0 Cd27 binding protein (Siva) zf-C3HC4_2 PF13923.1 EMC91553.1 - 0.51 10.4 18.8 2.9 7.9 2.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC91553.1 - 1.2 8.9 18.8 2.8 7.7 3.0 2.6 2 0 0 2 2 2 0 zinc-RING finger domain IBR PF01485.16 EMC91553.1 - 8.3 6.3 20.0 1.6 8.6 2.1 2.9 2 1 0 2 2 2 0 IBR domain zf-RING_2 PF13639.1 EMC91553.1 - 8.9 6.2 18.2 8.2 6.3 2.3 2.5 2 0 0 2 2 2 0 Ring finger domain RNA_pol PF00940.14 EMC91554.1 - 2.7e-161 536.6 0.0 3.7e-161 536.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EMC91554.1 - 5.9e-65 219.6 1.2 5.9e-65 219.6 0.9 3.2 3 1 1 4 4 4 1 DNA-directed RNA polymerase N-terminal BCIP PF13862.1 EMC91555.1 - 1.8e-64 216.8 0.1 2.3e-64 216.5 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DivIVA PF05103.8 EMC91556.1 - 1.9 8.5 13.5 0.19 11.8 1.0 3.2 2 1 1 3 3 3 0 DivIVA protein FUSC PF04632.7 EMC91556.1 - 3.5 5.9 11.5 0.13 10.6 3.8 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family MAS20 PF02064.10 EMC91557.1 - 5.9e-19 68.1 0.1 3e-18 65.8 0.1 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor MRP-L46 PF11788.3 EMC91557.1 - 0.034 14.8 0.1 0.044 14.4 0.1 1.2 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Vps51 PF08700.6 EMC91558.1 - 3.9e-16 58.6 2.6 3.9e-16 58.6 1.8 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 EMC91558.1 - 0.0023 17.7 0.1 0.92 9.2 0.0 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec5 DUF3166 PF11365.3 EMC91558.1 - 0.014 15.8 0.1 0.058 13.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) COG2 PF06148.6 EMC91558.1 - 0.067 13.0 0.2 0.067 13.0 0.1 2.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MtrG PF04210.8 EMC91558.1 - 0.39 10.4 1.5 0.92 9.2 1.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G LSM PF01423.17 EMC91560.1 - 7.5e-15 54.2 0.0 9.3e-15 53.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain His_Phos_2 PF00328.17 EMC91561.1 - 4.2e-17 62.5 0.0 1.3e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Phage_Coat_B PF05356.6 EMC91561.1 - 0.016 14.8 0.3 0.071 12.8 0.2 2.1 1 0 0 1 1 1 0 Phage Coat protein B SmpA_OmlA PF04355.8 EMC91561.1 - 0.053 13.1 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 SmpA / OmlA family CSF-1 PF05337.6 EMC91561.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) Clathrin PF00637.15 EMC91562.1 - 1.7e-21 76.3 3.4 1.6e-20 73.1 0.4 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 EMC91562.1 - 1.4e-17 63.2 0.0 3.8e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EMC91562.1 - 0.0011 18.6 5.8 0.0025 17.6 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.1 EMC91562.1 - 0.007 15.9 0.3 0.029 14.0 0.0 2.2 2 0 0 2 2 1 1 TPR repeat zf-RING_5 PF14634.1 EMC91562.1 - 0.0072 16.0 5.4 0.016 14.9 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC91562.1 - 0.0097 15.9 5.5 0.019 14.9 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC91562.1 - 0.011 15.5 0.6 0.031 14.0 0.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMC91562.1 - 0.021 14.9 1.3 0.049 13.7 0.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Pyr_excise PF03013.9 EMC91562.1 - 0.1 12.3 1.0 0.27 11.0 0.7 1.7 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase zf-C3HC4 PF00097.20 EMC91562.1 - 0.3 10.7 5.9 0.61 9.7 4.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 EMC91562.1 - 0.3 10.9 3.7 0.94 9.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC91562.1 - 0.72 9.9 5.1 0.29 11.1 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 EMC91562.1 - 0.73 9.7 5.0 1.7 8.5 3.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 EMC91562.1 - 1.1 8.9 3.9 2.4 7.9 2.7 1.6 1 0 0 1 1 1 0 PHD-finger DDHD PF02862.12 EMC91564.1 - 3.3e-42 144.8 0.0 9.1e-24 84.5 0.0 2.7 2 1 1 3 3 3 2 DDHD domain Abhydrolase_5 PF12695.2 EMC91564.1 - 0.0064 16.2 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC91564.1 - 0.028 14.2 0.2 0.028 14.2 0.1 2.7 2 2 1 3 3 3 0 Alpha/beta hydrolase family DUF202 PF02656.10 EMC91565.1 - 4.5e-20 71.6 1.4 4.5e-20 71.6 1.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) GWT1 PF06423.7 EMC91565.1 - 0.013 15.6 0.6 0.017 15.1 0.4 1.2 1 0 0 1 1 1 0 GWT1 Tetraspannin PF00335.15 EMC91565.1 - 0.053 12.7 1.1 0.26 10.5 0.9 1.9 2 0 0 2 2 2 0 Tetraspanin family COX4_pro_2 PF07835.7 EMC91565.1 - 0.064 13.2 0.1 0.064 13.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV CopD PF05425.8 EMC91565.1 - 0.083 13.0 6.4 0.57 10.4 2.5 2.1 2 0 0 2 2 2 0 Copper resistance protein D DUF3112 PF11309.3 EMC91565.1 - 5.3 6.8 7.3 1.8 8.3 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) DUF4131 PF13567.1 EMC91565.1 - 9 5.6 9.9 1.2 8.5 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Cofilin_ADF PF00241.15 EMC91566.1 - 2.2e-12 46.9 0.1 2.7e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ras PF00071.17 EMC91567.1 - 7.5e-58 194.4 0.2 8.8e-58 194.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC91567.1 - 2.8e-19 69.7 0.0 4.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC91567.1 - 1.1e-07 31.2 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC91567.1 - 9.1e-07 28.4 0.1 4.1e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC91567.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC91567.1 - 0.009 15.1 0.1 0.012 14.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EMC91567.1 - 0.019 14.2 0.1 0.054 12.7 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EMC91567.1 - 0.036 13.2 0.2 0.092 11.9 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EMC91567.1 - 0.043 13.2 0.7 0.84 9.0 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Bac_rhamnosid PF05592.6 EMC91568.1 - 5.1e-180 599.0 0.1 1.4e-179 597.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EMC91568.1 - 1.3e-48 164.7 0.2 4e-48 163.1 0.0 1.9 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Sugar_tr PF00083.19 EMC91569.1 - 5.3e-60 203.2 29.2 6.6e-60 202.9 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC91569.1 - 1.1e-15 57.1 34.1 1.1e-15 57.1 23.6 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF295 PF03478.13 EMC91570.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Fip1 PF05182.8 EMC91571.1 - 9.3e-18 63.2 1.2 1.5e-17 62.5 0.8 1.3 1 0 0 1 1 1 1 Fip1 motif YL1 PF05764.8 EMC91571.1 - 0.22 11.0 5.1 0.3 10.6 3.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Rrn6 PF10214.4 EMC91571.1 - 0.54 8.2 4.3 0.71 7.8 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SDA1 PF05285.7 EMC91571.1 - 1.4 8.1 6.3 1.7 7.8 4.3 1.1 1 0 0 1 1 1 0 SDA1 Nucleoporin_FG PF13634.1 EMC91572.1 - 3.6e-31 107.7 89.7 6.2e-16 58.6 23.7 3.3 1 1 2 3 3 3 3 Nucleoporin FG repeat region PTP_N PF12453.3 EMC91573.1 - 0.054 13.0 0.8 0.13 11.8 0.3 1.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal KOW PF00467.24 EMC91574.1 - 1.1e-07 31.2 1.8 3.8e-07 29.5 1.3 1.9 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.6 EMC91574.1 - 0.072 12.9 0.2 0.1 12.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) Ost4 PF10215.4 EMC91577.1 - 2e-17 62.3 1.7 2.6e-17 62.0 1.2 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase zf-CCCH PF00642.19 EMC91578.1 - 3.5e-05 23.3 1.4 3.5e-05 23.3 1.0 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cwf_Cwc_15 PF04889.7 EMC91578.1 - 0.0014 18.4 8.3 0.0014 18.4 5.7 3.2 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein NT-C2 PF10358.4 EMC91578.1 - 0.076 12.4 2.2 0.17 11.3 0.2 2.3 2 1 1 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins zf-TRAF PF02176.13 EMC91581.1 - 5.4e-09 36.2 19.2 0.00011 22.4 2.5 4.2 3 1 1 4 4 3 3 TRAF-type zinc finger zf-RING_2 PF13639.1 EMC91581.1 - 7.9e-08 32.0 13.7 7.9e-08 32.0 9.5 2.9 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC91581.1 - 3.4e-07 29.7 11.3 3.4e-07 29.7 7.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC91581.1 - 3.4e-06 26.6 5.7 3.4e-06 26.6 4.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMC91581.1 - 5.8e-06 25.9 10.8 5.8e-06 25.9 7.5 2.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC91581.1 - 1e-05 25.4 13.7 1e-05 25.4 9.5 3.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC91581.1 - 0.00012 21.6 11.1 0.00012 21.6 7.7 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC91581.1 - 0.0022 17.7 5.8 0.0022 17.7 4.0 2.6 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMC91581.1 - 0.01 15.9 7.3 0.01 15.9 5.1 3.0 2 2 0 2 2 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC91581.1 - 0.012 15.4 13.7 0.012 15.4 9.5 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Apc4 PF12896.2 EMC91581.1 - 0.029 13.6 0.3 3.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 zf-Nse PF11789.3 EMC91581.1 - 0.03 13.8 8.3 0.022 14.2 4.0 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EMC91581.1 - 9.3 6.1 23.2 0.033 13.9 6.3 3.1 2 1 1 3 3 3 0 zf-RING of BARD1-type protein DUF92 PF01940.11 EMC91582.1 - 7.3e-57 192.1 10.6 1.1e-56 191.5 7.3 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 CTP_transf_1 PF01148.15 EMC91582.1 - 0.097 12.3 9.5 0.018 14.7 3.7 1.9 2 1 0 2 2 2 0 Cytidylyltransferase family DUF3353 PF11833.3 EMC91582.1 - 3.3 7.1 7.4 16 4.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Histone PF00125.19 EMC91583.1 - 4.8e-11 42.6 0.1 6.6e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC91583.1 - 0.00016 21.6 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EMC91583.1 - 0.018 14.9 0.1 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) PCP_red PF08369.5 EMC91583.1 - 0.084 12.7 0.8 0.23 11.3 0.6 1.8 1 1 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit CENP-S PF15630.1 EMC91583.1 - 0.095 12.8 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S Svf1 PF08622.5 EMC91584.1 - 4.1e-118 394.0 0.0 4.7e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Svf1-like Pkinase PF00069.20 EMC91585.1 - 1.4e-62 211.2 0.1 3e-62 210.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC91585.1 - 1.5e-35 122.4 0.0 2.6e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EMC91585.1 - 3.4e-31 106.7 15.1 1.7e-16 59.7 3.2 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EMC91585.1 - 2.9e-19 68.5 30.2 8.5e-11 41.4 6.9 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMC91585.1 - 1.5e-13 51.0 2.1 4.4e-13 49.5 1.4 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC91585.1 - 0.029 13.3 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.1 EMC91585.1 - 0.046 13.6 8.4 0.098 12.6 0.9 2.6 2 0 0 2 2 2 0 Up-regulated During Septation Acetyltransf_7 PF13508.1 EMC91586.1 - 0.00023 21.2 0.0 0.00057 20.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC91586.1 - 0.00048 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC91586.1 - 0.0073 16.3 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Kei1 PF08552.6 EMC91588.1 - 2.8e-41 141.2 4.0 4.1e-41 140.7 2.7 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_M56 PF05569.6 EMC91588.1 - 0.054 12.4 0.1 0.054 12.4 0.1 2.0 2 1 1 3 3 3 0 BlaR1 peptidase M56 Ras PF00071.17 EMC91589.1 - 2.7e-57 192.6 0.1 3.5e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC91589.1 - 2.6e-20 73.0 0.1 3.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC91589.1 - 1.8e-15 56.5 0.1 2.2e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC91589.1 - 2.7e-05 23.4 0.0 4.4e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC91589.1 - 4.4e-05 23.4 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC91589.1 - 4.8e-05 22.6 0.1 5.7e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC91589.1 - 6.9e-05 22.3 0.0 0.00037 19.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMC91589.1 - 0.0014 17.8 0.0 0.091 12.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TIR_2 PF13676.1 EMC91589.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 TIR domain G-alpha PF00503.15 EMC91589.1 - 0.29 9.7 1.0 12 4.4 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Nop53 PF07767.6 EMC91590.1 - 5.7e-88 295.5 13.5 5.7e-88 295.5 9.3 1.3 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) MatE PF01554.13 EMC91591.1 - 4.7e-57 192.1 24.1 3e-31 108.2 6.0 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EMC91591.1 - 3.7e-06 26.7 7.4 3.7e-06 26.7 5.2 3.4 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Nuf2 PF03800.9 EMC91593.1 - 7.2e-43 146.0 0.1 2.5e-42 144.3 0.1 1.9 1 0 0 1 1 1 1 Nuf2 family Reo_sigmaC PF04582.7 EMC91593.1 - 0.019 14.1 11.7 0.066 12.3 0.8 2.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EMC91593.1 - 0.49 10.4 29.7 0.033 14.2 4.9 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 EMC91593.1 - 1.8 8.4 53.5 0.015 15.1 14.0 3.3 1 1 2 3 3 3 0 Tropomyosin like Laminin_II PF06009.7 EMC91593.1 - 7.2 6.3 25.8 0.97 9.1 1.7 3.5 1 1 2 3 3 3 0 Laminin Domain II GAS PF13851.1 EMC91593.1 - 8.1 5.5 46.5 2.7 7.1 8.5 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EMC91593.1 - 9.7 6.0 49.4 1.7 8.4 13.2 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Metallophos PF00149.23 EMC91595.1 - 2.1e-42 144.8 0.4 2.7e-42 144.4 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_N PF01602.15 EMC91597.1 - 8.3e-94 314.7 0.8 1.3e-93 314.1 0.5 1.2 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EMC91597.1 - 9.8e-12 45.0 10.5 0.00019 21.6 0.1 5.7 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 EMC91597.1 - 5.5e-11 41.5 4.2 0.0086 16.0 0.0 7.0 6 0 0 6 6 6 4 HEAT repeat Cohesin_HEAT PF12765.2 EMC91597.1 - 7.2e-05 22.6 0.7 0.57 10.2 0.1 3.1 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion RasGEF_N_2 PF14663.1 EMC91597.1 - 0.00015 21.6 0.5 0.52 10.2 0.0 3.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.1 EMC91597.1 - 0.00033 21.0 9.1 0.15 12.5 0.1 5.5 5 0 0 5 5 5 1 HEAT-like repeat DUF2435 PF10363.4 EMC91597.1 - 0.012 15.4 0.1 9.5 6.2 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EMC91597.1 - 0.3 10.4 1.4 9.7 5.4 0.0 3.3 2 2 1 3 3 3 0 CLASP N terminal DUF1237 PF06824.6 EMC91598.1 - 1.1e-177 590.8 0.0 1.3e-177 590.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) RRM_1 PF00076.17 EMC91600.1 - 4.3e-24 83.9 5.3 4.7e-12 45.3 0.3 3.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC91600.1 - 8.4e-17 60.7 1.1 1e-11 44.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC91600.1 - 6.2e-16 58.1 0.1 1.3e-07 31.5 0.1 3.1 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EMC91600.1 - 0.00034 20.2 0.3 0.0014 18.2 0.0 2.0 2 1 0 2 2 2 1 Calcipressin Limkain-b1 PF11608.3 EMC91600.1 - 0.012 15.3 0.3 0.097 12.4 0.0 2.4 2 1 0 3 3 3 0 Limkain b1 MFS_1 PF07690.11 EMC91601.1 - 6.9e-44 149.9 14.7 3e-41 141.3 7.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EMC91601.1 - 0.00048 18.9 0.0 0.00076 18.3 0.0 1.3 1 0 0 1 1 1 1 BT1 family MFS_1_like PF12832.2 EMC91601.1 - 0.0025 17.5 1.5 1.2 9.0 0.1 3.0 3 0 0 3 3 3 2 MFS_1 like family Mem_trans PF03547.13 EMC91601.1 - 0.022 13.0 0.0 0.065 11.5 0.0 1.7 2 0 0 2 2 2 0 Membrane transport protein OATP PF03137.15 EMC91601.1 - 0.078 11.0 0.1 2.2 6.2 0.4 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SNF2_N PF00176.18 EMC91603.1 - 1.2e-57 195.0 0.1 1.7e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC91603.1 - 6.8e-08 32.2 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC91603.1 - 6.3e-07 29.4 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 EMC91603.1 - 1.6e-05 24.5 6.1 2.9e-05 23.7 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 EMC91603.1 - 0.00036 20.0 0.0 0.00096 18.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EMC91603.1 - 0.0013 18.3 6.9 0.0035 16.9 4.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC91603.1 - 0.0014 18.2 4.7 0.0024 17.4 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC91603.1 - 0.0083 16.1 6.1 0.019 14.9 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC91603.1 - 0.031 14.0 6.1 0.076 12.8 4.2 1.7 1 0 0 1 1 1 0 Ring finger domain AAA_11 PF13086.1 EMC91603.1 - 0.072 12.6 0.7 17 4.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain zf-C3HC4_4 PF15227.1 EMC91603.1 - 2.2 8.2 6.3 5.1 7.0 4.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ion_trans PF00520.26 EMC91604.1 - 1.2e-06 27.9 19.2 3.2e-06 26.5 13.3 1.7 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 EMC91604.1 - 0.00032 19.2 20.8 0.013 13.9 14.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel Synaptobrevin PF00957.16 EMC91605.1 - 3.8e-31 106.5 0.0 5.1e-31 106.1 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EMC91605.1 - 6e-22 77.0 0.0 8.8e-22 76.4 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1833 PF08875.6 EMC91605.1 - 0.083 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) Tautomerase_3 PF14832.1 EMC91606.1 - 3.4e-11 43.3 0.0 5.8e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EMC91606.1 - 0.012 15.1 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme eIF-1a PF01176.14 EMC91607.1 - 5.2e-12 44.9 0.0 7.8e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 EMC91608.1 - 2.7e-138 461.2 13.8 3.1e-138 461.0 9.6 1.0 1 0 0 1 1 1 1 ALG3 protein adh_short PF00106.20 EMC91609.1 - 8.5e-22 77.8 0.1 1.1e-19 71.0 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EMC91609.1 - 3.8e-12 46.2 0.3 2.6e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMC91609.1 - 4.7e-09 36.3 0.0 2.6e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 EMC91609.1 - 0.00014 20.8 0.0 0.0003 19.7 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMC91609.1 - 0.00022 21.2 0.4 0.041 13.8 0.3 3.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMC91609.1 - 0.0027 16.7 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EMC91609.1 - 0.0028 16.9 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMC91609.1 - 0.003 17.0 0.0 0.0045 16.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC91609.1 - 0.012 14.5 0.0 0.053 12.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMC91609.1 - 0.15 10.7 0.0 0.26 9.9 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family IF-2B PF01008.12 EMC91610.1 - 2.8e-50 170.9 0.0 3.5e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EMC91610.1 - 0.014 15.0 0.2 1.9 8.1 0.0 2.6 3 0 0 3 3 3 0 DeoR C terminal sensor domain LKAAEAR PF15478.1 EMC91610.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif Cpn60_TCP1 PF00118.19 EMC91611.1 - 1.1e-139 466.1 11.4 1.6e-138 462.3 7.9 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2036 PF09724.4 EMC91612.1 - 7e-21 74.7 0.0 8.9e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Hemerythrin PF01814.18 EMC91613.1 - 1.4e-12 47.9 3.8 1.9e-12 47.5 2.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain IL6 PF00489.12 EMC91613.1 - 0.044 13.3 0.1 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family SH3_9 PF14604.1 EMC91614.1 - 1.4e-07 30.9 0.1 3.1e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC91614.1 - 1.4e-05 24.3 0.3 2.7e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 SH3 domain PPR_2 PF13041.1 EMC91616.1 - 0.084 12.8 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family PPR_1 PF12854.2 EMC91616.1 - 0.16 11.4 0.4 0.5 9.8 0.3 1.8 1 0 0 1 1 1 0 PPR repeat Pkinase PF00069.20 EMC91617.1 - 4e-31 108.1 0.0 1.5e-19 70.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC91617.1 - 7.8e-14 51.3 0.0 1.3e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase GAF PF01590.21 EMC91617.1 - 0.027 14.5 0.6 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 GAF domain RabGAP-TBC PF00566.13 EMC91618.1 - 1.1e-37 129.6 0.0 1.4e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAD_binding_3 PF01494.14 EMC91619.1 - 2.6e-71 240.5 0.0 3.3e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMC91619.1 - 1.9e-37 128.4 0.0 3.2e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EMC91619.1 - 0.0093 16.3 0.0 0.065 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC91619.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC91619.1 - 0.013 14.4 0.0 0.036 12.9 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC91619.1 - 0.015 15.1 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC91619.1 - 0.04 13.0 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EMC91619.1 - 0.043 12.7 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EMC91619.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EMC91619.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family Glyco_hydro_43 PF04616.9 EMC91620.1 - 3.7e-22 78.7 0.5 5.1e-22 78.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Radical_SAM PF04055.16 EMC91621.1 - 1.2e-10 41.7 0.0 3.8e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 EMC91621.1 - 6.4e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMC91621.1 - 0.0027 17.7 0.1 0.006 16.5 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1054 PF06335.7 EMC91621.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) DUF2605 PF10792.4 EMC91621.1 - 0.12 12.0 0.1 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) tRNA_int_endo PF01974.12 EMC91622.1 - 1.6e-15 56.6 0.0 3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Sugar_tr PF00083.19 EMC91624.1 - 1.9e-89 300.2 25.8 2.5e-89 299.9 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC91624.1 - 7.8e-13 47.8 47.0 1.9e-09 36.7 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.24 EMC91626.1 - 6.7e-36 123.3 0.0 1.2e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC91626.1 - 2.1e-20 72.3 0.0 1e-18 66.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Beta-Casp PF10996.3 EMC91626.1 - 0.00085 19.2 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 2 Beta-Casp domain AAA_19 PF13245.1 EMC91626.1 - 0.0014 18.3 0.7 0.12 12.1 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain ResIII PF04851.10 EMC91626.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EMC91626.1 - 0.034 13.4 0.9 0.39 9.9 0.6 2.2 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_10 PF12846.2 EMC91626.1 - 0.11 11.9 0.0 0.39 10.0 0.0 1.8 1 1 1 2 2 2 0 AAA-like domain Anp1 PF03452.9 EMC91627.1 - 2.4e-118 394.1 0.0 3.5e-118 393.6 0.0 1.2 1 0 0 1 1 1 1 Anp1 Glyco_tranf_2_4 PF13704.1 EMC91627.1 - 0.042 14.1 0.1 0.16 12.2 0.1 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 Rad54_N PF08658.5 EMC91627.1 - 0.079 12.7 0.4 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Rad54 N terminal CLTH PF10607.4 EMC91629.1 - 4e-32 110.9 0.0 5.2e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EMC91629.1 - 5.8e-08 32.2 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 LisH PRK PF00485.13 EMC91630.1 - 4.4e-57 192.7 0.0 5.9e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EMC91630.1 - 7.7e-35 119.9 0.0 1.3e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EMC91630.1 - 9.2e-09 36.1 0.0 4e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 EMC91630.1 - 9e-06 25.4 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EMC91630.1 - 0.00018 20.7 0.0 0.00032 19.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EMC91630.1 - 0.00078 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC91630.1 - 0.0024 17.7 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EMC91630.1 - 0.013 15.7 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 EMC91630.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.24 EMC91630.1 - 0.028 14.6 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC91630.1 - 0.031 14.2 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EMC91630.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EMC91630.1 - 0.21 12.0 0.3 2 8.9 0.1 2.1 1 1 1 2 2 2 0 Miro-like protein IBR PF01485.16 EMC91631.1 - 1.2e-19 69.8 20.6 1.2e-11 44.2 3.9 4.0 3 1 1 4 4 4 2 IBR domain Elf1 PF05129.8 EMC91631.1 - 0.088 12.5 23.0 0.62 9.7 0.3 3.6 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like zf-RING_2 PF13639.1 EMC91631.1 - 0.15 11.8 37.3 0.11 12.3 6.6 3.4 3 0 0 3 3 3 0 Ring finger domain PhnA_Zn_Ribbon PF08274.7 EMC91631.1 - 0.29 10.9 0.1 0.29 10.9 0.1 4.9 5 0 0 5 5 5 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.1 EMC91631.1 - 0.82 9.2 0.1 0.82 9.2 0.1 4.8 6 1 1 7 7 7 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 EMC91631.1 - 8.5 6.5 39.0 3 7.9 1.9 4.8 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF4385 PF14328.1 EMC91632.1 - 3.8e-51 172.8 0.4 5.4e-51 172.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) MFS_1 PF07690.11 EMC91633.1 - 1.4e-08 33.8 37.4 2.4e-07 29.8 7.8 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily DUF4231 PF14015.1 EMC91633.1 - 0.58 10.1 3.2 1.4 8.9 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Radical_SAM PF04055.16 EMC91634.1 - 1.4e-23 83.9 0.0 4e-23 82.3 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EMC91634.1 - 9.3e-22 76.9 0.0 2.5e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EMC91634.1 - 4.7e-11 42.8 0.0 1.3e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 EMC91634.1 - 0.075 13.0 0.1 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain IBR PF01485.16 EMC91635.1 - 0.078 12.8 36.0 0.019 14.8 6.3 3.5 2 1 1 3 3 3 0 IBR domain TFCD_C PF12612.3 EMC91636.1 - 3.8e-18 65.6 2.8 3.7e-17 62.3 0.8 3.3 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.2 EMC91636.1 - 0.02 15.2 0.1 0.31 11.4 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF2267 PF10025.4 EMC91636.1 - 0.096 12.7 3.0 0.18 11.8 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Cnd1 PF12717.2 EMC91636.1 - 0.12 12.2 0.4 3.4 7.4 0.0 3.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMC91636.1 - 1.1 9.5 17.1 1.1 9.4 0.1 6.3 7 0 0 7 7 7 0 HEAT repeat CDC27 PF09507.5 EMC91637.1 - 6.4e-87 292.5 23.4 7.5e-87 292.3 16.2 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 MOR2-PAG1_N PF14222.1 EMC91638.1 - 8.8e-179 595.7 0.0 3.1e-178 593.9 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EMC91638.1 - 5e-86 288.7 0.1 1.2e-85 287.4 0.0 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EMC91638.1 - 1.6e-32 112.1 1.8 2e-13 48.9 0.1 3.2 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT PF02985.17 EMC91638.1 - 0.038 14.0 0.6 15 5.9 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Transglut_i_TM PF14400.1 EMC91641.1 - 0.051 13.0 0.2 0.091 12.2 0.1 1.6 1 1 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices DUF348 PF03990.9 EMC91641.1 - 0.087 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF348) DHFR_2 PF06442.6 EMC91641.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 R67 dihydrofolate reductase TRF PF08558.5 EMC91642.1 - 3e-53 180.6 0.0 4.3e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EMC91642.1 - 0.00018 21.4 0.0 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC91642.1 - 0.017 15.2 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain F-box-like PF12937.2 EMC91643.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 F-box-like Pex2_Pex12 PF04757.9 EMC91644.1 - 5.2e-56 189.6 4.4 7.1e-56 189.1 3.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EMC91644.1 - 3.4e-05 23.7 0.5 5.5e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC91644.1 - 0.0013 18.6 0.4 0.0022 17.8 0.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC91644.1 - 0.0017 18.1 0.4 0.0028 17.4 0.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC91644.1 - 0.0034 16.9 0.3 0.0056 16.3 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC91644.1 - 0.025 14.2 0.2 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DASH_Dad1 PF08649.5 EMC91645.1 - 1.8e-25 88.3 1.7 2.1e-25 88.1 1.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 PilJ PF13675.1 EMC91645.1 - 0.017 15.4 0.1 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term WVELL PF14043.1 EMC91645.1 - 0.056 13.0 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 WVELL protein ATP_bind_3 PF01171.15 EMC91646.1 - 1.8e-38 131.8 0.0 3.4e-38 130.9 0.0 1.4 1 1 0 1 1 1 1 PP-loop family zf-B_box PF00643.19 EMC91647.1 - 1.1 9.2 13.9 0.1 12.4 4.6 2.7 3 0 0 3 3 3 0 B-box zinc finger Pkinase PF00069.20 EMC91648.1 - 1.7e-59 201.0 0.0 2.7e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC91648.1 - 1.7e-20 73.2 0.0 3.7e-20 72.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMC91648.1 - 0.018 14.7 1.1 0.038 13.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC91648.1 - 0.077 11.9 0.2 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Acetyltransf_1 PF00583.19 EMC91649.1 - 4.3e-08 33.0 0.1 7.4e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMC91649.1 - 1.2e-05 25.4 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC91649.1 - 0.00015 21.8 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EMC91649.1 - 0.0008 19.0 0.1 0.0016 18.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC91649.1 - 0.0012 18.6 0.2 0.0033 17.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC91649.1 - 0.0033 17.2 1.6 0.0063 16.3 0.2 2.1 2 1 1 3 3 3 1 GCN5-related N-acetyl-transferase DUF1768 PF08719.6 EMC91650.1 - 6.9e-23 81.1 0.2 8.3e-23 80.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF651 PF04895.7 EMC91650.1 - 0.092 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF651) MFS_1 PF07690.11 EMC91651.1 - 2.3e-25 89.0 62.8 1.5e-18 66.6 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tfb4 PF03850.9 EMC91652.1 - 2.6e-98 328.6 0.0 3.2e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 EMC91652.1 - 0.057 13.1 4.0 0.11 12.2 2.8 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Glyco_hydro_35 PF01301.14 EMC91653.1 - 8.7e-86 288.1 0.0 1.3e-85 287.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EMC91653.1 - 3.6e-61 205.7 1.9 6.2e-61 204.9 1.3 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EMC91653.1 - 1.2e-50 170.4 15.2 5.2e-28 97.5 3.6 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EMC91653.1 - 1.2e-19 69.4 0.1 3.1e-19 68.1 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Asparaginase_2 PF01112.13 EMC91654.1 - 4.5e-35 120.8 1.5 1.9e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.14 EMC91655.1 - 1.4e-89 300.2 0.0 3.2e-89 299.0 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMC91655.1 - 0.0069 15.0 0.0 0.39 9.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Fungal_trans PF04082.13 EMC91656.1 - 1.9e-19 69.5 0.0 3.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC91656.1 - 1.2e-05 25.0 6.9 2.5e-05 24.0 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRMT5 PF05185.11 EMC91657.1 - 1.4e-167 558.1 0.0 1.8e-167 557.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase G-patch PF01585.18 EMC91658.1 - 1.3e-07 31.2 0.1 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC91658.1 - 0.031 14.0 0.5 0.066 13.0 0.3 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site SNARE PF05739.14 EMC91659.1 - 1.5e-12 46.9 5.5 1.5e-12 46.9 3.8 1.9 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 EMC91659.1 - 2.3e-07 30.5 1.3 6.3e-07 29.0 0.9 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.8 EMC91659.1 - 0.0087 15.7 1.0 0.13 11.9 0.1 2.6 2 1 1 3 3 3 1 Sec20 EMP24_GP25L PF01105.19 EMC91659.1 - 0.19 11.4 5.1 0.32 10.6 0.8 2.4 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Cluap1 PF10234.4 EMC91659.1 - 1.9 7.6 8.6 2.2 7.4 2.8 2.7 2 1 0 2 2 2 0 Clusterin-associated protein-1 Myb_Cef PF11831.3 EMC91660.1 - 2.1e-52 177.6 0.3 2.1e-52 177.6 0.2 3.8 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EMC91660.1 - 3.8e-19 68.4 2.4 1.3e-08 34.7 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC91660.1 - 6.1e-19 67.8 4.5 2.2e-12 46.8 0.8 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain IBN_N PF03810.14 EMC91662.1 - 1.3e-09 37.8 0.0 1.1e-08 34.8 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMC91662.1 - 7.6e-06 25.8 0.0 0.0018 18.1 0.0 3.0 2 0 0 2 2 2 1 Exportin 1-like protein Arm PF00514.18 EMC91662.1 - 0.068 13.0 0.3 0.69 9.8 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CAS_CSE1 PF03378.10 EMC91662.1 - 0.082 11.1 0.0 0.14 10.4 0.0 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus HORMA PF02301.13 EMC91664.1 - 7.3e-27 94.2 0.0 8.3e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 HORMA domain RasGEF PF00617.14 EMC91665.1 - 0.046 13.4 0.4 0.076 12.7 0.3 1.3 1 0 0 1 1 1 0 RasGEF domain DUF2540 PF10802.3 EMC91665.1 - 0.063 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) F-box-like PF12937.2 EMC91665.1 - 0.1 12.3 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like Amidohydro_1 PF01979.15 EMC91666.1 - 3.6e-29 102.4 0.0 5.1e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC91666.1 - 2.2e-15 57.4 0.0 2.3e-07 31.1 0.0 2.6 1 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EMC91666.1 - 2e-11 43.7 2.4 8.5e-10 38.4 0.1 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMC91666.1 - 4.8e-07 29.5 0.2 1.5e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Acyltransferase PF01553.16 EMC91667.1 - 5e-16 58.3 0.0 1.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase PAXNEB PF05625.6 EMC91669.1 - 1.1e-101 340.2 0.0 1.3e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Med8 PF10232.4 EMC91669.1 - 0.083 12.3 0.8 0.97 8.9 0.2 2.1 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF775 PF05603.7 EMC91670.1 - 5.4e-57 192.5 0.0 6.1e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EMC91671.1 - 5.2e-07 29.3 0.4 1e-06 28.4 0.3 1.4 1 0 0 1 1 1 1 NUDIX domain TRI5 PF06330.6 EMC91673.1 - 5.2e-149 495.9 1.6 6e-149 495.7 1.1 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Fibrinogen_aC PF12160.3 EMC91673.1 - 0.11 11.9 0.4 19 4.8 0.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha C domain p450 PF00067.17 EMC91674.1 - 3.6e-52 177.4 0.0 4.8e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Npa1 PF11707.3 EMC91675.1 - 3.3e-62 210.4 0.0 5e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal IFN-gamma PF00714.12 EMC91675.1 - 0.017 14.9 0.1 0.41 10.4 0.0 2.5 2 0 0 2 2 2 0 Interferon gamma Glyco_hydro_47 PF01532.15 EMC91675.1 - 0.24 10.0 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 AAA_10 PF12846.2 EMC91675.1 - 0.25 10.7 1.7 5.5 6.3 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain Met_10 PF02475.11 EMC91677.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.7 1 1 0 1 1 1 1 Met-10+ like-protein Osmo_CC PF08946.5 EMC91677.1 - 0.038 14.0 0.3 0.08 12.9 0.2 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil EF-hand_6 PF13405.1 EMC91678.1 - 2.9e-05 23.5 0.7 0.042 13.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMC91678.1 - 0.0017 17.5 0.2 0.004 16.3 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EMC91678.1 - 0.002 18.2 0.5 0.0062 16.6 0.4 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC91678.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF3608 PF12257.3 EMC91679.1 - 1e-46 159.1 1.2 4.7e-45 153.6 0.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EMC91679.1 - 2e-22 78.6 0.2 4.4e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GST_N_2 PF13409.1 EMC91680.1 - 2.4e-20 72.2 0.0 6e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC91680.1 - 2.2e-14 53.0 0.0 9.2e-14 51.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC91680.1 - 8.6e-08 32.0 0.0 2.4e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC91680.1 - 1.2e-06 28.6 0.1 3.4e-05 23.9 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC91680.1 - 0.00044 20.6 0.0 0.0018 18.6 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.17 EMC91681.1 - 0.00018 21.0 0.0 0.0043 16.6 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC91681.1 - 0.00023 20.9 1.8 0.00027 20.6 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC91681.1 - 0.00023 21.0 0.0 0.00088 19.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mitoc_L55 PF09776.4 EMC91681.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 DUF604 PF04646.7 EMC91682.1 - 1.2e-08 34.5 0.0 1.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EMC91682.1 - 2.4e-07 30.2 0.0 4.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_90 PF05686.7 EMC91683.1 - 1.2e-23 83.5 2.0 1.6e-23 83.1 1.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 BCL9 PF11502.3 EMC91683.1 - 4.5 6.8 7.2 0.6 9.6 0.1 2.5 3 0 0 3 3 3 0 B-cell lymphoma 9 protein HAD PF12710.2 EMC91684.1 - 3.7e-12 46.8 0.0 5.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EMC91684.1 - 0.0007 18.8 0.0 0.0061 15.7 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 EMC91684.1 - 0.033 13.5 0.1 0.098 11.9 0.0 1.9 2 1 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) She9_MDM33 PF05546.6 EMC91685.1 - 3e-54 183.7 4.6 4.9e-54 183.0 3.2 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family Sec8_exocyst PF04048.9 EMC91685.1 - 0.47 10.0 6.3 1.3 8.6 0.3 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF1681 PF07933.9 EMC91686.1 - 1.9e-52 177.0 0.0 2.5e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Ribosom_S12_S23 PF00164.20 EMC91687.1 - 1e-42 144.4 1.2 1.2e-42 144.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTK3_C PF12350.3 EMC91688.1 - 0.9 9.6 3.6 17 5.5 0.1 3.2 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus RNase_T PF00929.19 EMC91689.1 - 5.8e-21 75.4 0.0 9.6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EMC91689.1 - 0.014 14.9 0.0 0.077 12.4 0.0 2.0 1 1 0 1 1 1 0 3'-5' exonuclease MOZ_SAS PF01853.13 EMC91690.1 - 6.8e-85 283.0 0.1 9.6e-85 282.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EMC91690.1 - 1.9e-23 81.8 0.0 3.9e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EMC91690.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_7 PF13508.1 EMC91690.1 - 0.083 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1918 PF08940.6 EMC91690.1 - 0.086 12.1 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Acetyltransf_1 PF00583.19 EMC91690.1 - 0.089 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-U1 PF06220.7 EMC91690.1 - 0.23 11.0 3.1 0.57 9.7 2.2 1.6 1 0 0 1 1 1 0 U1 zinc finger IBR PF01485.16 EMC91691.1 - 1e-15 57.2 22.5 5.2e-09 35.8 7.9 3.4 3 1 0 3 3 3 2 IBR domain DRP PF06044.7 EMC91691.1 - 0.0072 15.3 3.8 0.64 8.9 0.0 2.1 2 0 0 2 2 2 2 Dam-replacing family zf-H2C2_2 PF13465.1 EMC91691.1 - 0.63 10.4 0.1 0.63 10.4 0.0 4.5 5 2 1 6 6 6 0 Zinc-finger double domain FeS PF04060.8 EMC91691.1 - 7.2 6.2 8.5 0.48 10.0 1.5 2.4 2 0 0 2 2 2 0 Putative Fe-S cluster DEAD PF00270.24 EMC91692.1 - 2.7e-45 153.8 0.0 4.9e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EMC91692.1 - 1.9e-22 78.7 6.0 8.6e-22 76.7 4.0 2.3 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EMC91692.1 - 3.8e-21 74.7 0.0 1.4e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RPA_C PF08784.6 EMC91693.1 - 3.2e-15 56.3 0.6 6.6e-15 55.3 0.4 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EMC91693.1 - 4.8e-06 26.3 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BOF PF04076.8 EMC91693.1 - 0.022 14.5 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial OB fold (BOF) protein adh_short PF00106.20 EMC91694.1 - 6e-17 62.0 0.1 7.7e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC91694.1 - 3.3e-09 36.6 0.1 7.1e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC91694.1 - 7.5e-09 35.7 0.2 1.1e-08 35.1 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF460 PF04312.8 EMC91694.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF866 PF05907.8 EMC91696.1 - 1.1e-47 161.5 0.3 1.2e-47 161.3 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF3716 PF12511.3 EMC91696.1 - 0.086 12.4 3.0 0.17 11.5 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PHD PF00628.24 EMC91696.1 - 0.095 12.4 0.8 0.2 11.4 0.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-like PF04071.7 EMC91696.1 - 0.14 11.8 1.6 0.37 10.5 1.1 1.7 1 1 0 1 1 1 0 Cysteine-rich small domain DUF4379 PF14311.1 EMC91696.1 - 0.75 9.6 4.9 0.19 11.5 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4379) Pyr_redox_2 PF07992.9 EMC91698.1 - 1.6e-19 70.5 0.0 2.3e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC91698.1 - 3.2e-11 43.4 0.0 1.5e-08 34.9 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EMC91698.1 - 5.5e-06 25.3 0.1 1.6e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EMC91698.1 - 9.7e-06 25.0 0.8 6e-05 22.5 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EMC91698.1 - 1.5e-05 25.0 0.2 5.8e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC91698.1 - 4.2e-05 22.6 0.5 0.00011 21.3 0.4 1.7 1 0 0 1 1 1 1 EF hand Aldedh PF00171.17 EMC91699.1 - 6.4e-125 417.0 0.0 7.2e-125 416.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC91699.1 - 5e-08 32.0 0.0 7.2e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) LRR_9 PF14580.1 EMC91702.1 - 1.7e-54 184.0 0.8 1.9e-54 183.8 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 EMC91702.1 - 9.4e-13 47.7 15.3 9.5e-07 28.4 1.2 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EMC91702.1 - 3.1e-09 36.2 10.0 0.0013 18.3 0.6 4.3 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC91702.1 - 0.077 13.0 9.9 16 6.0 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.1 EMC91702.1 - 2.7 8.3 4.2 31 5.0 0.2 4.1 5 0 0 5 5 5 0 Leucine Rich repeat DIM1 PF02966.11 EMC91703.1 - 1.5e-69 231.6 0.6 1.7e-69 231.4 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EMC91703.1 - 0.00055 20.0 0.8 0.0012 18.9 0.6 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 EMC91703.1 - 0.00073 19.1 0.0 0.00091 18.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EMC91703.1 - 0.056 13.4 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.6 EMC91703.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Clr2 PF10383.4 EMC91704.1 - 1.8e-16 60.3 0.0 4.5e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 SNF2_N PF00176.18 EMC91705.1 - 4.9e-59 199.5 0.1 9.7e-59 198.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC91705.1 - 6.4e-10 38.7 0.0 2.2e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMC91705.1 - 5.4e-08 31.9 0.0 1.6e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 EMC91705.1 - 4.3e-05 23.1 9.1 4.3e-05 23.1 6.3 2.8 2 1 1 3 3 3 1 PHD-finger AAA_22 PF13401.1 EMC91705.1 - 0.037 14.1 0.2 7.5 6.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain C1_1 PF00130.17 EMC91705.1 - 3.7 7.3 20.7 5.4 6.8 3.0 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2530 PF10745.4 EMC91707.1 - 0.036 14.0 1.8 0.066 13.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) YlaH PF14036.1 EMC91707.1 - 2.7 8.1 6.8 14 5.8 0.0 2.7 3 0 0 3 3 3 0 YlaH-like protein MoCF_biosynth PF00994.19 EMC91708.1 - 1.7e-34 118.3 0.0 2.9e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain FAD_syn PF06574.7 EMC91708.1 - 0.043 13.4 0.0 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 FAD synthetase DUF221 PF02714.10 EMC91709.1 - 3.9e-110 367.7 16.1 3.9e-110 367.7 11.2 2.2 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMC91709.1 - 1.9e-37 128.2 2.1 1.9e-37 128.2 1.5 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMC91709.1 - 2.8e-30 104.0 0.2 5.1e-30 103.2 0.1 1.4 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EMC91709.1 - 5.3e-21 74.9 1.5 9.3e-21 74.1 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_5 PF13893.1 EMC91709.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase PF00117.23 EMC91712.1 - 7.3e-42 143.0 0.0 1.5e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EMC91712.1 - 7.9e-30 102.4 0.0 2.2e-29 101.0 0.0 1.8 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EMC91712.1 - 1.1e-10 40.8 0.1 5.4e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EMC91712.1 - 2.3e-10 40.2 0.0 5.2e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 EMC91712.1 - 7.3e-05 22.3 0.1 0.00033 20.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 EMC91712.1 - 0.00013 21.3 0.1 0.00099 18.4 0.1 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EMC91712.1 - 0.00022 19.9 0.3 0.0008 18.0 0.1 1.8 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 EMC91712.1 - 0.00035 20.1 0.0 0.00078 19.0 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 EMC91712.1 - 0.00071 18.7 0.1 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.15 EMC91712.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.14 EMC91712.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiF PF00899.16 EMC91714.1 - 4.6e-07 29.7 0.0 8.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family DUF2277 PF10041.4 EMC91714.1 - 0.07 13.1 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Rib_5-P_isom_A PF06026.9 EMC91715.1 - 3.5e-38 130.6 0.0 4.8e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) GATA PF00320.22 EMC91716.1 - 7e-35 118.0 17.3 1.4e-17 62.7 3.5 2.1 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EMC91716.1 - 3.1e-06 26.3 6.2 0.0038 16.5 0.6 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 EMC91716.1 - 8.8e-06 25.4 4.7 0.00019 21.2 3.5 2.5 1 1 1 2 2 2 2 Double zinc ribbon Zn-ribbon_8 PF09723.5 EMC91716.1 - 0.00013 21.8 1.9 0.061 13.2 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain RRN7 PF11781.3 EMC91716.1 - 0.00043 19.7 4.8 0.013 14.9 0.3 2.6 2 1 1 3 3 3 1 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5_eIF-2B PF01873.12 EMC91716.1 - 0.00064 19.3 4.3 0.047 13.3 0.2 2.2 2 0 0 2 2 2 2 Domain found in IF2B/IF5 ArfGap PF01412.13 EMC91716.1 - 0.0011 18.6 3.3 0.1 12.3 0.1 2.1 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.6 EMC91716.1 - 0.0024 17.5 5.1 0.18 11.5 0.5 2.3 2 0 0 2 2 2 2 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.10 EMC91716.1 - 0.0039 16.7 6.7 0.0083 15.6 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger HypA PF01155.14 EMC91716.1 - 0.0051 16.4 2.6 0.063 12.9 0.3 2.2 1 1 1 2 2 2 1 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 EMC91716.1 - 0.013 15.1 3.3 2.3 7.9 0.3 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 EMC91716.1 - 0.017 14.2 13.5 0.28 10.4 1.9 3.4 2 2 0 2 2 2 0 zinc-ribbon domain zf-C4pol PF14260.1 EMC91716.1 - 0.02 14.8 3.5 0.06 13.3 2.4 1.8 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-CHY PF05495.7 EMC91716.1 - 0.025 14.7 2.4 0.16 12.1 0.9 2.2 1 1 1 2 2 2 0 CHY zinc finger Auto_anti-p27 PF06677.7 EMC91716.1 - 0.025 14.3 5.4 1.4 8.7 0.4 2.6 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DNA_RNApol_7kD PF03604.8 EMC91716.1 - 0.037 13.4 8.8 1.2 8.6 0.9 3.8 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Prim_Zn_Ribbon PF08273.7 EMC91716.1 - 0.041 13.9 11.0 1.7 8.7 2.3 3.1 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase Lar_restr_allev PF14354.1 EMC91716.1 - 0.071 13.4 5.7 3 8.2 0.5 3.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-CSL PF05207.8 EMC91716.1 - 0.076 12.5 0.7 0.6 9.6 0.1 2.4 2 1 0 2 2 2 0 CSL zinc finger zf-FCS PF06467.9 EMC91716.1 - 0.096 12.3 6.2 13 5.5 0.0 3.9 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-RING_5 PF14634.1 EMC91716.1 - 0.098 12.4 5.7 4.8 6.9 0.1 3.5 3 1 0 3 3 3 0 zinc-RING finger domain zf-UBR PF02207.15 EMC91716.1 - 0.15 11.8 3.7 0.27 10.9 0.1 2.2 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF3511 PF12023.3 EMC91716.1 - 0.18 11.1 1.8 0.34 10.2 1.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF3511) zf-C2H2_3 PF13878.1 EMC91716.1 - 0.2 11.2 12.7 0.61 9.6 0.1 3.8 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO FYVE PF01363.16 EMC91716.1 - 0.55 10.1 4.9 3.6 7.5 0.6 2.4 1 1 1 2 2 2 0 FYVE zinc finger Baculo_ME53 PF06061.6 EMC91716.1 - 0.73 8.7 4.5 5.3 5.9 0.3 2.8 1 1 2 3 3 3 0 Baculoviridae ME53 zf-C3HC4 PF00097.20 EMC91716.1 - 1.1 8.9 4.5 0.81 9.3 0.2 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EMC91716.1 - 1.6 8.8 4.4 4.7 7.2 0.2 2.5 2 1 0 2 2 2 0 zinc-finger Ribosomal_L32p PF01783.18 EMC91716.1 - 2.2 8.5 18.2 0.76 9.9 1.4 4.1 4 1 0 4 4 3 0 Ribosomal L32p protein family zinc_ribbon_2 PF13240.1 EMC91716.1 - 2.3 7.8 13.2 2.3 7.7 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain RNHCP PF12647.2 EMC91716.1 - 2.4 8.0 6.1 3.1 7.7 1.8 2.7 1 1 3 4 4 4 0 RNHCP domain C1_1 PF00130.17 EMC91716.1 - 2.6 7.8 5.7 4.9 6.9 0.5 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EMC91716.1 - 2.7 8.1 7.1 22 5.1 1.5 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rpr2 PF04032.11 EMC91716.1 - 3.9 7.4 6.1 9.2 6.2 2.6 2.6 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_S27e PF01667.12 EMC91716.1 - 9.3 5.8 9.3 4.5 6.8 0.6 3.0 2 1 1 3 3 3 0 Ribosomal protein S27 ADK_lid PF05191.9 EMC91716.1 - 9.5 5.9 10.1 25 4.6 1.8 3.9 3 1 0 3 3 3 0 Adenylate kinase, active site lid COPI_assoc PF08507.5 EMC91717.1 - 8.7e-43 145.3 5.2 9.6e-43 145.1 3.6 1.0 1 0 0 1 1 1 1 COPI associated protein DUF3096 PF11295.3 EMC91717.1 - 1.6 8.2 11.7 1.6 8.3 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) DUF2636 PF11120.3 EMC91717.1 - 1.9 8.0 4.9 1.1 8.7 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) DUF308 PF03729.8 EMC91717.1 - 3.4 7.7 19.8 13 5.8 1.4 3.1 1 1 2 3 3 3 0 Short repeat of unknown function (DUF308) FUSC-like PF12805.2 EMC91717.1 - 3.5 6.4 4.4 1.6 7.5 1.6 1.3 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS DAO PF01266.19 EMC91718.1 - 1.9e-28 99.3 1.8 2.4e-28 99.0 1.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC91718.1 - 1.9e-05 24.6 0.1 5.1e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMC91718.1 - 0.00012 21.2 0.8 0.00021 20.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EMC91718.1 - 0.00023 20.1 0.0 0.00034 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EMC91718.1 - 0.0019 16.9 0.1 0.014 14.0 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EMC91718.1 - 0.0032 17.3 0.7 0.0047 16.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC91718.1 - 0.0059 15.6 0.2 0.055 12.5 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 EMC91718.1 - 0.011 16.1 0.2 0.028 14.8 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC91718.1 - 0.097 11.5 0.2 0.29 9.9 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein OTU PF02338.14 EMC91719.1 - 1.6e-15 57.7 0.0 2.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EMC91719.1 - 0.0011 18.3 0.6 0.89 8.8 0.1 2.9 2 1 1 3 3 3 2 Peptidase C65 Otubain Phlebovirus_G1 PF07243.6 EMC91720.1 - 0.015 13.4 2.3 0.015 13.4 1.6 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 ProRS-C_1 PF09180.6 EMC91721.1 - 6.8e-23 80.3 0.2 1.5e-22 79.2 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EMC91721.1 - 1.1e-18 67.3 0.8 1.9e-18 66.6 0.6 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC91721.1 - 2.2e-14 53.1 0.0 5.5e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Rieske PF00355.21 EMC91722.1 - 2.4e-17 62.2 0.1 5.5e-17 61.1 0.0 1.7 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EMC91722.1 - 3.8e-17 62.2 0.2 7.9e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Macro PF01661.16 EMC91723.1 - 1.7e-20 73.1 0.0 3.4e-20 72.1 0.0 1.5 1 1 0 1 1 1 1 Macro domain Terpene_synth_C PF03936.11 EMC91724.1 - 2.2e-11 43.4 0.0 3.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HEAT_2 PF13646.1 EMC91725.1 - 3.8e-32 110.4 3.5 9.8e-15 54.6 0.9 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 EMC91725.1 - 5.8e-19 66.5 4.3 0.0028 17.9 0.2 6.7 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EMC91725.1 - 5.3e-08 33.1 9.4 0.0082 16.6 0.0 5.5 3 2 3 6 6 6 3 HEAT-like repeat HEAT PF02985.17 EMC91725.1 - 3.8e-06 26.5 6.5 0.5 10.5 0.0 6.0 8 0 0 8 8 8 3 HEAT repeat Nipped-B_C PF12830.2 EMC91726.1 - 4.3e-47 160.1 5.9 1.8e-45 154.9 0.4 3.7 3 1 1 4 4 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EMC91726.1 - 7e-07 29.0 2.9 3.1e-05 23.8 0.2 3.1 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EMC91726.1 - 0.00063 19.6 4.2 0.15 12.1 0.1 5.7 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.2 EMC91726.1 - 0.00091 19.1 2.0 0.017 14.9 0.1 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Sin_N PF04801.8 EMC91727.1 - 7.7e-32 110.6 0.1 3.4e-31 108.5 0.1 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region PNTB PF02233.11 EMC91728.1 - 9.1e-169 562.0 23.9 9.1e-169 562.0 16.5 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EMC91728.1 - 2.4e-54 183.4 1.1 4.5e-54 182.5 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EMC91728.1 - 1.7e-38 131.7 0.0 7.5e-38 129.6 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EMC91728.1 - 1.6e-31 108.2 3.7 1.6e-31 108.2 2.6 5.0 5 1 0 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EMC91728.1 - 9.4e-05 21.6 0.1 1.3 8.1 0.0 3.4 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 EMC91728.1 - 0.0053 16.5 0.7 0.017 14.8 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 EMC91728.1 - 0.066 13.0 0.5 0.3 10.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CP_ATPgrasp_1 PF04174.8 EMC91728.1 - 0.088 11.4 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Methyltransf_31 PF13847.1 EMC91728.1 - 0.24 10.9 0.0 0.69 9.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 EMC91728.1 - 0.74 9.8 6.0 0.28 11.2 0.4 3.3 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain SKG6 PF08693.5 EMC91729.1 - 3.5e-05 23.0 1.0 7.5e-05 21.9 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EMC91729.1 - 0.0055 16.3 0.0 0.0067 16.1 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family Syndecan PF01034.15 EMC91729.1 - 0.024 14.2 0.3 0.043 13.4 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 EMC91729.1 - 0.025 13.4 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EMC91729.1 - 0.065 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 EMC91729.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protocadherin vMSA PF00695.14 EMC91729.1 - 8.7 5.4 9.4 3 6.9 0.1 2.3 1 1 1 2 2 2 0 Major surface antigen from hepadnavirus Ank_2 PF12796.2 EMC91730.1 - 0.00014 22.1 0.0 0.00049 20.3 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMC91730.1 - 0.00054 19.9 0.0 0.4 11.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EMC91730.1 - 0.061 13.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.1 EMC91730.1 - 0.1 13.1 0.0 9.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) MMS1_N PF10433.4 EMC91732.1 - 2.4e-82 276.6 0.0 7.9e-82 274.9 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EMC91732.1 - 2.8e-75 253.3 0.0 7.7e-71 238.7 0.0 3.1 3 0 0 3 3 3 2 CPSF A subunit region LVIVD PF08309.6 EMC91732.1 - 0.069 12.1 0.0 0.33 9.9 0.0 2.2 2 0 0 2 2 2 0 LVIVD repeat DEAD PF00270.24 EMC91733.1 - 3.3e-39 134.0 0.0 8.5e-39 132.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC91733.1 - 5.9e-21 74.1 0.0 1.5e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EMC91733.1 - 1.9e-16 59.3 0.3 5.6e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EMC91733.1 - 0.0036 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATP-synt_D PF01813.12 EMC91734.1 - 6.5e-63 211.8 1.5 8.7e-63 211.4 1.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Nup54 PF13874.1 EMC91734.1 - 2.7 7.6 7.2 0.84 9.2 0.5 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Sigma70_ner PF04546.8 EMC91734.1 - 2.8 7.5 11.1 3.2 7.3 4.6 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region FadA PF09403.5 EMC91734.1 - 3.1 7.8 7.8 2.4 8.2 3.3 2.2 2 0 0 2 2 2 0 Adhesion protein FadA Atg14 PF10186.4 EMC91734.1 - 3.7 6.3 6.2 11 4.8 1.8 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GMC_oxred_N PF00732.14 EMC91735.1 - 5e-61 206.4 0.0 8.2e-61 205.7 0.0 1.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC91735.1 - 2.5e-31 108.9 0.0 4.7e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMC91735.1 - 1.5e-07 30.7 0.1 9.8e-05 21.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC91735.1 - 4.8e-05 23.5 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC91735.1 - 5.7e-05 23.0 0.3 0.00019 21.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC91735.1 - 0.00065 18.6 0.2 0.0015 17.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EMC91735.1 - 0.0017 17.3 0.1 0.0029 16.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMC91735.1 - 0.015 15.2 0.1 0.042 13.7 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC91735.1 - 0.12 10.8 0.5 0.28 9.5 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EMC91735.1 - 0.12 11.4 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family PEMT PF04191.8 EMC91737.1 - 1.1e-55 186.1 15.8 6.8e-36 122.6 0.6 2.8 3 0 0 3 3 3 2 Phospholipid methyltransferase NIR_SIR PF01077.17 EMC91738.1 - 4.1e-51 172.4 0.1 2.4e-43 147.2 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EMC91738.1 - 3e-32 110.0 0.1 3.3e-15 55.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EMC91738.1 - 1e-26 93.6 0.0 2.1e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EMC91738.1 - 8.2e-10 38.5 0.1 2.1e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DHC_N1 PF08385.7 EMC91738.1 - 0.87 7.8 0.0 1.5 7.0 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 CTNNBL PF08216.6 EMC91740.1 - 1.6e-31 108.1 0.5 6.3e-31 106.1 0.0 2.2 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EMC91740.1 - 0.0031 17.7 4.9 0.0071 16.5 0.5 3.4 3 1 1 4 4 4 1 HEAT repeats MMS19_C PF12460.3 EMC91740.1 - 0.053 12.2 1.3 1.8 7.2 0.0 2.3 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Pyridox_oxidase PF01243.15 EMC91741.1 - 0.0077 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1446 PF07287.6 EMC91742.1 - 1.5e-130 434.9 0.1 1.7e-130 434.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Asp PF00026.18 EMC91743.1 - 2.4e-70 237.2 7.2 3.2e-70 236.8 5.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC91743.1 - 4.6e-06 26.6 1.7 1.8e-05 24.7 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMC91743.1 - 0.00025 21.4 1.8 0.031 14.7 0.3 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EMC91743.1 - 0.028 13.9 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_C48 PF02902.14 EMC91744.1 - 3.1e-13 49.8 0.0 5.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRN9 PF10680.4 EMC91744.1 - 0.099 12.3 1.9 0.4 10.4 1.3 2.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor DASH_Dad3 PF08656.5 EMC91752.1 - 1.5e-25 88.6 0.4 1.8e-25 88.4 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.20 EMC91753.1 - 3.6e-69 232.7 0.0 2.8e-68 229.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC91753.1 - 5.4e-30 104.3 0.0 3.2e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMC91753.1 - 5.1e-06 25.6 0.2 0.054 12.4 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EMC91753.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC91753.1 - 0.027 14.2 0.0 0.38 10.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arrestin_C PF02752.17 EMC91754.1 - 2.2e-16 60.1 0.0 7.5e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Polysacc_deac_1 PF01522.16 EMC91754.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase Pro_isomerase PF00160.16 EMC91755.1 - 5.6e-46 156.5 0.0 6.4e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Skp1_POZ PF03931.10 EMC91756.1 - 3.5e-09 36.6 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain ThiF PF00899.16 EMC91757.1 - 3.7e-38 130.4 3.6 5.7e-30 103.9 0.0 2.8 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EMC91757.1 - 2.5e-27 94.2 0.0 6e-27 93.0 0.0 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMC91757.1 - 2.9e-22 77.7 1.4 2.9e-22 77.7 1.0 2.1 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EMC91757.1 - 2e-08 34.2 1.0 4e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DUF2419 PF10343.4 EMC91758.1 - 2.2e-113 378.3 0.0 1.4e-73 247.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) SLT PF01464.15 EMC91759.1 - 0.018 14.4 0.1 0.045 13.2 0.1 1.7 1 1 0 1 1 1 0 Transglycosylase SLT domain Rad60-SLD_2 PF13881.1 EMC91760.1 - 1.9e-10 40.6 0.0 3.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMC91760.1 - 0.056 13.6 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EMC91760.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family UMP1 PF05348.6 EMC91763.1 - 8.7e-25 87.1 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 HET PF06985.6 EMC91766.1 - 2.2e-18 66.7 0.0 2.4e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NMD3 PF04981.8 EMC91767.1 - 2.8e-73 245.9 1.0 3.7e-73 245.5 0.7 1.2 1 0 0 1 1 1 1 NMD3 family Nif11 PF07862.6 EMC91767.1 - 0.0082 16.0 0.1 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Nitrogen fixation protein of unknown function Plasmid_RAQPRD PF09686.5 EMC91767.1 - 0.11 12.5 0.9 0.37 10.8 0.3 2.1 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DZR PF12773.2 EMC91767.1 - 0.15 11.8 5.4 0.74 9.6 1.6 2.7 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 EMC91767.1 - 0.66 9.9 3.6 3.1 7.7 0.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger C1_1 PF00130.17 EMC91767.1 - 5 6.9 5.5 1.6 8.5 0.1 2.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PAP2 PF01569.16 EMC91768.1 - 4.4e-18 65.2 6.2 4.4e-18 65.2 4.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily Ras PF00071.17 EMC91769.1 - 1.5e-48 164.2 0.0 1.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC91769.1 - 2.3e-11 44.2 0.0 4.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC91769.1 - 2.5e-05 23.5 0.0 4.5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC91769.1 - 0.035 13.3 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMC91769.1 - 0.092 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DHC_N1 PF08385.7 EMC91770.1 - 9.2e-156 519.5 0.0 9.2e-156 519.5 0.0 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EMC91770.1 - 7.5e-129 429.8 1.2 7.5e-129 429.8 0.8 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EMC91770.1 - 1.3e-99 334.1 0.0 2.7e-99 333.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EMC91770.1 - 3.4e-79 265.6 0.0 8e-79 264.4 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EMC91770.1 - 2.2e-42 144.9 0.0 3.2e-41 141.0 0.0 2.6 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EMC91770.1 - 2.5e-42 144.8 3.9 4.3e-42 144.1 2.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 EMC91770.1 - 3.9e-41 140.3 0.0 2e-40 138.0 0.0 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 EMC91770.1 - 2.1e-29 102.0 0.1 7.1e-11 41.9 0.0 6.1 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EMC91770.1 - 5.8e-19 68.2 0.0 1.1e-17 64.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EMC91770.1 - 4.4e-17 62.4 0.0 0.0089 16.1 0.0 7.2 7 0 0 7 7 5 3 AAA domain AAA PF00004.24 EMC91770.1 - 5.6e-13 49.2 0.0 0.0018 18.5 0.0 5.1 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMC91770.1 - 2.3e-10 40.5 0.8 0.13 12.1 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_17 PF13207.1 EMC91770.1 - 3.7e-10 40.6 0.1 0.047 14.5 0.0 6.1 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.1 EMC91770.1 - 1.8e-08 34.7 0.0 0.085 13.1 0.0 4.8 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 EMC91770.1 - 6.4e-08 31.8 0.0 0.01 14.7 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EMC91770.1 - 2.2e-06 27.3 1.5 1.1 8.6 0.0 5.0 5 0 0 5 5 4 2 FtsK/SpoIIIE family AAA_19 PF13245.1 EMC91770.1 - 8.3e-06 25.4 0.2 0.81 9.4 0.0 4.8 4 0 0 4 4 4 1 Part of AAA domain AAA_14 PF13173.1 EMC91770.1 - 1.4e-05 24.9 0.0 0.73 9.7 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EMC91770.1 - 1.5e-05 24.4 0.0 2 7.9 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EMC91770.1 - 0.00018 20.7 2.9 0.34 10.0 0.0 4.5 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EMC91770.1 - 0.0002 21.6 0.6 5.4 7.3 0.0 4.8 4 0 0 4 4 3 0 ABC transporter DUF258 PF03193.11 EMC91770.1 - 0.013 14.6 0.0 6.7 5.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EMC91770.1 - 0.014 15.5 0.4 19 5.4 0.0 4.3 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 EMC91770.1 - 0.069 12.8 0.9 28 4.4 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EMC91770.1 - 0.21 11.0 4.9 9.3 5.7 0.0 4.3 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EMC91770.1 - 0.32 10.5 2.6 28 4.1 0.0 4.0 4 0 0 4 4 4 0 AAA domain UCH PF00443.24 EMC91770.1 - 0.84 8.6 5.6 9.3 5.2 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase AAA_11 PF13086.1 EMC91770.1 - 1 8.8 12.1 1.9 7.9 0.0 4.7 5 0 0 5 5 4 0 AAA domain TMF_DNA_bd PF12329.3 EMC91770.1 - 1.7 8.4 19.5 6.5 6.6 5.0 4.3 4 0 0 4 4 3 0 TATA element modulatory factor 1 DNA binding AAA_23 PF13476.1 EMC91770.1 - 4.9 7.4 12.2 95 3.2 0.0 5.5 6 0 0 6 6 5 0 AAA domain Methyltransf_33 PF10017.4 EMC91772.1 - 1e-33 115.9 0.0 1.8e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EMC91772.1 - 3.6e-15 56.0 1.0 2.4e-13 50.0 0.7 2.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EMC91772.1 - 0.00029 21.1 1.0 0.00067 19.9 0.7 1.7 1 0 0 1 1 1 1 DinB superfamily Ribosomal_L23 PF00276.15 EMC91774.1 - 2.8e-10 39.9 0.0 1.5e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L23 Sec7 PF01369.15 EMC91775.1 - 6e-63 211.9 0.1 9.5e-63 211.3 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EMC91775.1 - 7.3e-20 71.0 0.0 2.6e-13 49.7 0.0 2.8 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EMC91775.1 - 0.017 14.6 0.1 6.4 6.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Zn_clus PF00172.13 EMC91776.1 - 4.1e-05 23.3 10.2 6e-05 22.8 7.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.5 EMC91776.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold Sec1 PF00995.18 EMC91777.1 - 7.8e-134 447.3 0.0 9.1e-134 447.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PAT1 PF09770.4 EMC91777.1 - 4.6 5.3 12.6 8.4 4.4 8.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SUV3_C PF12513.3 EMC91778.1 - 1.6e-15 56.2 0.0 3.6e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EMC91778.1 - 2.3e-09 36.9 0.1 6e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fungal_trans PF04082.13 EMC91779.1 - 1.1e-26 93.2 0.0 2e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC91779.1 - 5.6e-09 35.7 8.1 9.5e-09 35.0 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMC91779.1 - 0.011 14.3 1.7 0.051 12.1 0.0 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain GILT PF03227.11 EMC91781.1 - 1.2e-13 50.8 0.2 2.5e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) YjgP_YjgQ PF03739.9 EMC91781.1 - 0.0056 15.4 0.1 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family CM_2 PF01817.16 EMC91783.1 - 3.7e-08 33.3 0.2 9.7e-05 22.3 0.0 3.6 3 1 0 3 3 3 2 Chorismate mutase type II WD40 PF00400.27 EMC91784.1 - 3.1e-37 125.1 8.8 1.6e-09 37.2 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EMC91784.1 - 1.6e-08 33.2 6.7 0.0018 16.4 0.0 4.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMC91784.1 - 0.0062 16.0 0.3 0.24 10.8 0.1 2.4 2 0 0 2 2 2 1 PQQ-like domain APG6 PF04111.7 EMC91784.1 - 0.014 14.4 8.3 0.02 13.9 5.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Phage_GP20 PF06810.6 EMC91784.1 - 0.035 13.5 6.7 0.06 12.7 4.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 EMC91784.1 - 0.042 13.4 6.2 0.071 12.6 4.3 1.3 1 0 0 1 1 1 0 IncA protein Nucleoporin_N PF08801.6 EMC91784.1 - 0.062 12.0 0.0 9.9 4.7 0.0 3.1 3 1 0 3 3 3 0 Nup133 N terminal like IFT57 PF10498.4 EMC91784.1 - 0.097 11.3 3.9 0.18 10.4 2.7 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nairo_nucleo PF02477.10 EMC91784.1 - 0.33 9.6 1.1 0.5 8.9 0.7 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein HrpB7 PF09486.5 EMC91784.1 - 0.57 10.0 8.6 1.4 8.8 6.0 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Striatin PF08232.7 EMC91784.1 - 1.3 9.3 9.9 2.7 8.3 6.7 1.5 1 1 0 1 1 1 0 Striatin family BTV_NS2 PF04514.7 EMC91784.1 - 3 6.6 7.1 4.4 6.0 4.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MerR-DNA-bind PF09278.6 EMC91784.1 - 8 6.9 10.1 10 6.6 0.2 3.7 3 1 1 4 4 4 0 MerR, DNA binding IBR PF01485.16 EMC91787.1 - 4.8e-07 29.5 39.1 0.00025 20.8 5.8 3.5 2 1 1 3 3 3 2 IBR domain ParA PF10609.4 EMC91788.1 - 5.9e-36 122.2 0.0 1.2e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMC91788.1 - 8.5e-16 57.9 0.0 1.2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMC91788.1 - 5.3e-06 26.4 0.0 2.5e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EMC91788.1 - 0.00022 20.3 0.4 0.0033 16.5 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EMC91788.1 - 0.00064 18.8 0.0 0.00098 18.2 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EMC91788.1 - 0.0029 17.0 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EMC91788.1 - 0.011 15.3 0.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMC91788.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 EMC91788.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EMC91788.1 - 0.041 13.6 0.1 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RNA_helicase PF00910.17 EMC91788.1 - 0.052 13.7 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 RNA helicase Fer4_NifH PF00142.13 EMC91788.1 - 0.087 11.9 0.0 0.45 9.6 0.0 2.1 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EMC91788.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EMC91788.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMC91788.1 - 0.12 11.2 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MFS_1 PF07690.11 EMC91793.1 - 2.8e-20 72.3 44.0 1.7e-17 63.1 30.8 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily ThiF PF00899.16 EMC91794.1 - 5.3e-52 175.2 0.0 2.1e-32 111.8 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EMC91794.1 - 4.8e-39 131.7 3.5 5.7e-27 93.0 0.5 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EMC91794.1 - 6e-38 129.8 0.1 1.6e-37 128.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EMC91794.1 - 3.4e-25 87.1 1.4 2.4e-21 74.8 0.5 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EMC91794.1 - 0.0019 18.4 0.0 0.11 12.7 0.0 3.1 3 0 0 3 3 3 1 Putative NAD(P)-binding Cyclin_N PF00134.18 EMC91795.1 - 1.1e-15 57.3 0.4 9.7e-14 51.0 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 EMC91795.1 - 0.0051 16.6 0.3 0.011 15.5 0.2 1.6 1 1 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EMC91795.1 - 0.21 11.5 3.4 18 5.3 0.0 3.2 2 1 1 3 3 3 0 Cyclin, C-terminal domain DUF4452 PF14618.1 EMC91797.1 - 7.2e-50 169.0 10.8 1.1e-49 168.3 7.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) B12D PF06522.6 EMC91798.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit P120R PF08062.6 EMC91798.1 - 0.42 10.9 6.2 1.2 9.5 4.3 1.7 1 0 0 1 1 1 0 P120R (NUC006) repeat ATP-synt_E PF05680.7 EMC91798.1 - 2.4 8.1 6.8 5.3 7.0 4.7 1.6 1 1 0 1 1 1 0 ATP synthase E chain ADH_zinc_N PF00107.21 EMC91799.1 - 4e-32 110.5 0.7 6.6e-32 109.7 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC91799.1 - 4.9e-16 59.7 0.0 1.1e-15 58.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC91799.1 - 5.1e-10 39.0 0.0 1.4e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EMC91799.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain DUF3337 PF11816.3 EMC91801.1 - 2.6e-76 257.1 0.0 1.1e-71 242.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EMC91801.1 - 4.8e-31 105.4 14.8 5.8e-09 35.4 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EMC91801.1 - 0.0087 14.2 1.7 0.22 9.6 1.4 2.7 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 EMC91801.1 - 0.044 12.4 0.0 0.081 11.5 0.0 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Amidase PF01425.16 EMC91802.1 - 4.2e-71 240.1 0.0 5e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Amidase WD40 PF00400.27 EMC91804.1 - 3.9e-63 207.2 12.4 3.1e-10 39.5 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat HET PF06985.6 EMC91804.1 - 4.9e-21 75.3 2.3 8.1e-19 68.1 1.3 2.9 2 1 0 2 2 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EMC91804.1 - 3.8e-07 29.9 0.0 8.3e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.6 EMC91804.1 - 4.2e-07 29.8 0.0 0.13 11.9 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.1 EMC91804.1 - 1e-05 25.6 0.2 2.7e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EMC91804.1 - 5e-05 22.3 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.15 EMC91804.1 - 0.0011 18.6 0.1 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EMC91804.1 - 0.005 16.9 0.2 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC91804.1 - 0.0088 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Apc4_WD40 PF12894.2 EMC91804.1 - 0.0097 15.3 0.1 2.1 7.9 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_30 PF13604.1 EMC91804.1 - 0.016 14.7 0.1 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PD40 PF07676.7 EMC91804.1 - 0.017 14.8 1.6 66 3.3 0.0 5.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat AAA_17 PF13207.1 EMC91804.1 - 0.023 15.5 0.1 0.21 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMC91804.1 - 0.03 14.4 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.1 EMC91804.1 - 0.03 14.6 0.3 0.15 12.3 0.2 2.3 2 1 0 2 2 1 0 AAA domain MobB PF03205.9 EMC91804.1 - 0.035 13.8 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.12 EMC91804.1 - 0.049 12.4 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.24 EMC91804.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Proteasome_A_N PF10584.4 EMC91804.1 - 0.14 11.5 0.1 6.1 6.2 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Thymidylate_kin PF02223.12 EMC91804.1 - 0.16 11.2 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase NTPase_1 PF03266.10 EMC91804.1 - 0.18 11.5 0.0 0.75 9.4 0.0 1.9 2 0 0 2 2 2 0 NTPase PIF1 PF05970.9 EMC91804.1 - 0.33 9.8 0.0 0.76 8.6 0.0 1.5 2 0 0 2 2 2 0 PIF1-like helicase FAD_binding_3 PF01494.14 EMC91806.1 - 3.6e-12 46.0 0.0 6.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thr_synth_N PF14821.1 EMC91807.1 - 1.5e-29 101.8 0.0 3.8e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EMC91807.1 - 4.6e-17 62.1 0.0 4.2e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_6 PF12697.2 EMC91809.1 - 3.8e-07 30.2 0.0 4.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC91809.1 - 0.025 14.3 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CorA PF01544.13 EMC91810.1 - 0.00018 20.6 2.6 0.0007 18.7 1.8 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4401 PF14351.1 EMC91810.1 - 0.0023 16.9 0.7 0.0029 16.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) WBP-1 PF11669.3 EMC91810.1 - 0.079 13.0 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 Rep_1 PF01446.12 EMC91810.1 - 0.15 11.4 0.0 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 Replication protein SieB PF14163.1 EMC91810.1 - 0.24 10.9 1.4 0.4 10.2 1.0 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B HisKA_3 PF07730.8 EMC91810.1 - 3 8.2 6.5 2.8 8.3 1.1 2.8 2 1 1 3 3 3 0 Histidine kinase Myb_DNA-binding PF00249.26 EMC91812.1 - 0.034 14.1 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF2703 PF10865.3 EMC91812.1 - 0.081 12.8 0.0 11 5.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) PHD PF00628.24 EMC91813.1 - 5.3e-10 38.8 5.4 1.1e-09 37.7 3.8 1.6 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.20 EMC91813.1 - 5.4e-06 25.7 0.0 9.4e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EMC91813.1 - 6.9e-06 25.9 1.4 0.00037 20.2 0.7 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 EMC91813.1 - 0.0032 16.7 0.0 0.0064 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) ROKNT PF08067.6 EMC91813.1 - 0.022 14.5 1.5 0.022 14.5 1.0 1.9 2 0 0 2 2 2 0 ROKNT (NUC014) domain Kdo PF06293.9 EMC91813.1 - 0.071 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pyridox_oxase_2 PF12766.2 EMC91814.1 - 1.6e-20 73.2 0.0 3.1e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SET PF00856.23 EMC91815.1 - 1.6e-12 48.0 0.0 6.2e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 SET domain PAM2 PF07145.10 EMC91815.1 - 0.052 13.0 0.8 0.16 11.5 0.6 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Myc_target_1 PF15179.1 EMC91815.1 - 0.95 9.0 7.6 1.6 8.2 5.3 1.3 1 0 0 1 1 1 0 Myc target protein 1 RIO1 PF01163.17 EMC91816.1 - 1.1e-39 135.7 0.0 2.7e-39 134.4 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EMC91816.1 - 2.9e-31 107.3 0.0 5.6e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EMC91816.1 - 1.7e-05 24.7 4.5 0.085 12.5 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC91816.1 - 6.2e-05 22.1 0.0 0.019 14.0 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_27 PF13463.1 EMC91816.1 - 0.0097 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain Pmp3 PF01679.12 EMC91817.1 - 1.8e-19 69.1 6.1 2.3e-19 68.8 4.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Voltage_CLC PF00654.15 EMC91818.1 - 5.7e-91 305.1 25.7 5.7e-91 305.1 17.8 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EMC91818.1 - 1.3e-13 50.5 0.1 1.7e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain PC_rep PF01851.17 EMC91819.1 - 1.3e-18 66.0 18.7 3.5e-07 30.0 0.3 8.7 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMC91819.1 - 2.9e-07 30.6 1.4 0.095 12.9 0.0 4.7 4 0 0 4 4 4 2 HEAT repeats OB_NTP_bind PF07717.11 EMC91820.1 - 4.6e-28 97.3 0.0 9.4e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC91820.1 - 6.5e-22 77.4 0.7 1.4e-21 76.4 0.1 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMC91820.1 - 4.4e-10 39.2 0.0 9.6e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC91820.1 - 4.1e-07 29.6 0.5 9.6e-07 28.4 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMC91820.1 - 3.3e-05 24.0 0.1 0.00013 22.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EMC91820.1 - 0.0011 18.4 0.4 0.0039 16.6 0.3 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EMC91820.1 - 0.0042 16.8 0.1 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EMC91820.1 - 0.007 16.2 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EMC91820.1 - 0.021 13.7 0.0 0.049 12.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EMC91820.1 - 0.027 14.4 0.0 0.11 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 EMC91820.1 - 0.066 12.4 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 EMC91820.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Glyco_transf_17 PF04724.8 EMC91821.1 - 1.9e-46 158.7 0.1 3.7e-46 157.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 17 Joubert PF15392.1 EMC91822.1 - 0.0032 16.7 4.2 0.0038 16.5 2.9 1.0 1 0 0 1 1 1 1 Joubert syndrome-associated zf-U1 PF06220.7 EMC91823.1 - 0.023 14.2 0.3 0.048 13.2 0.2 1.5 1 0 0 1 1 1 0 U1 zinc finger HET PF06985.6 EMC91824.1 - 3.7e-23 82.2 0.0 6.3e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EMC91825.1 - 2.4e-39 133.5 12.7 1.2e-08 35.1 0.0 7.2 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC91825.1 - 2.1e-29 101.3 4.1 0.00019 21.8 0.1 8.4 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC91825.1 - 3.1e-26 88.8 6.9 0.00011 22.0 0.0 11.6 12 0 0 12 12 12 5 Ankyrin repeat Ank_5 PF13857.1 EMC91825.1 - 1.6e-25 88.4 12.3 9.5e-05 22.5 0.1 9.2 7 3 2 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.25 EMC91825.1 - 1.9e-25 87.3 14.7 2.3e-05 23.9 0.0 12.6 12 0 0 12 12 12 6 Ankyrin repeat NACHT PF05729.7 EMC91825.1 - 5.5e-07 29.4 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMC91825.1 - 5.1e-06 26.6 0.0 2.6e-05 24.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC91825.1 - 0.00088 19.3 0.1 0.00088 19.3 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 EMC91825.1 - 0.02 15.1 0.0 0.062 13.5 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMC91825.1 - 0.028 14.6 0.0 0.095 12.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Arch_ATPase PF01637.13 EMC91825.1 - 0.15 11.7 0.0 0.55 9.8 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase Peptidase_S41 PF03572.13 EMC91826.1 - 3.1e-06 26.6 0.0 8.9e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 WD40 PF00400.27 EMC91828.1 - 0.42 10.5 2.7 21 5.2 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat MFS_1 PF07690.11 EMC91832.1 - 5.2e-42 143.8 34.8 5.2e-42 143.8 24.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC91832.1 - 2.8e-15 55.8 12.5 3.2e-15 55.6 8.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMC91832.1 - 4.1e-09 35.2 2.0 6e-09 34.6 1.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EMC91832.1 - 0.31 9.0 6.3 1.6 6.6 3.9 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Nop14 PF04147.7 EMC91832.1 - 7.8 4.2 8.3 10 3.8 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family Mito_carr PF00153.22 EMC91833.1 - 3.4e-51 170.9 7.8 1.1e-18 66.7 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 EMC91833.1 - 0.0047 16.9 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 Corticotropin-releasing factor family Pro-kuma_activ PF09286.6 EMC91834.1 - 1.3e-38 132.2 0.1 2.8e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMC91834.1 - 1.8e-09 37.1 1.0 3e-09 36.4 0.7 1.3 1 0 0 1 1 1 1 Subtilase family Metallophos PF00149.23 EMC91835.1 - 9.7e-38 129.5 0.0 1.2e-32 112.9 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC91835.1 - 0.0038 17.0 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain CDC45 PF02724.9 EMC91835.1 - 0.057 11.4 0.4 0.077 11.0 0.3 1.2 1 0 0 1 1 1 0 CDC45-like protein LRR_4 PF12799.2 EMC91837.1 - 9.7e-28 95.2 18.5 2.7e-06 26.8 1.8 7.1 6 1 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC91837.1 - 1.2e-17 63.4 30.0 7.5e-06 25.6 2.7 6.2 5 1 1 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 EMC91837.1 - 5.5e-09 35.1 6.3 1.1 9.5 0.1 7.2 5 2 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 EMC91837.1 - 2.2e-05 23.8 32.7 0.88 9.8 0.3 11.6 11 2 1 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC91837.1 - 0.0018 18.1 29.0 2.3 8.7 0.1 10.4 11 0 0 11 11 11 3 Leucine rich repeat Gly-zipper_OmpA PF13436.1 EMC91838.1 - 0.024 14.3 3.1 0.05 13.2 2.2 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain FA_desaturase PF00487.19 EMC91838.1 - 0.024 14.0 0.2 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Lon_C PF05362.8 EMC91839.1 - 9.7e-69 230.7 0.5 2e-68 229.7 0.4 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EMC91839.1 - 3.1e-30 105.3 0.7 5.9e-30 104.4 0.1 1.8 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EMC91839.1 - 2.4e-24 86.0 0.0 1.5e-23 83.4 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC91839.1 - 9.7e-09 35.0 0.0 4e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EMC91839.1 - 3.5e-08 33.0 0.0 1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EMC91839.1 - 4.3e-06 26.8 0.7 2.7e-05 24.2 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMC91839.1 - 7.4e-06 26.7 0.2 6.4e-05 23.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EMC91839.1 - 2.6e-05 23.1 0.4 9.2e-05 21.3 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 EMC91839.1 - 4.5e-05 23.1 0.1 0.00023 20.8 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMC91839.1 - 4.5e-05 22.9 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EMC91839.1 - 4.8e-05 22.9 0.0 0.00018 21.1 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EMC91839.1 - 0.00022 21.1 0.0 0.00066 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMC91839.1 - 0.00029 19.9 0.3 0.0022 17.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMC91839.1 - 0.00039 20.3 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC91839.1 - 0.0005 20.2 0.0 0.0045 17.1 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EMC91839.1 - 0.00085 18.7 0.0 0.0029 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC91839.1 - 0.0026 17.6 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC91839.1 - 0.0035 16.4 0.0 0.0067 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_11 PF13086.1 EMC91839.1 - 0.014 14.9 0.9 0.25 10.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EMC91839.1 - 0.016 14.4 0.1 0.04 13.0 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EMC91839.1 - 0.016 14.8 0.0 0.049 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC91839.1 - 0.024 14.2 0.1 0.047 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EMC91839.1 - 0.025 13.8 0.0 0.067 12.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 EMC91839.1 - 0.029 13.9 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EMC91839.1 - 0.029 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EMC91839.1 - 0.029 14.6 0.1 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC91839.1 - 0.037 13.6 0.0 0.098 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EMC91839.1 - 0.044 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_PrkA PF08298.6 EMC91839.1 - 0.06 12.0 0.1 0.62 8.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.1 EMC91839.1 - 0.061 13.6 0.0 0.061 13.6 0.0 2.9 1 1 1 2 2 1 0 AAA domain AAA_28 PF13521.1 EMC91839.1 - 0.18 11.7 1.0 0.31 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain MT-A70 PF05063.9 EMC91840.1 - 2.6e-30 105.2 0.0 3.6e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Mito_carr PF00153.22 EMC91841.1 - 3.1e-62 206.3 0.9 1.4e-21 76.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Smg4_UPF3 PF03467.10 EMC91842.1 - 9.4e-21 74.5 0.0 9.4e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_6 PF14259.1 EMC91842.1 - 8.6e-05 22.4 0.0 0.00028 20.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC91842.1 - 0.00012 21.8 0.0 0.0003 20.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC91842.1 - 0.0023 17.5 0.0 0.0096 15.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1675 PF07897.6 EMC91842.1 - 7.1 6.4 10.0 11 5.8 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MIP PF00230.15 EMC91843.1 - 1.2e-48 165.5 17.0 1.3e-48 165.4 11.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Kinesin PF00225.18 EMC91845.1 - 1.7e-89 299.8 5.7 2.6e-89 299.2 0.0 3.5 2 1 0 2 2 2 1 Kinesin motor domain ERM PF00769.14 EMC91845.1 - 0.0019 17.7 27.8 0.0019 17.7 19.3 8.3 4 1 4 8 8 8 1 Ezrin/radixin/moesin family IncA PF04156.9 EMC91845.1 - 0.0056 16.2 3.4 0.0056 16.2 2.3 9.3 6 2 2 8 8 8 4 IncA protein TMF_DNA_bd PF12329.3 EMC91845.1 - 0.017 14.9 0.4 0.017 14.9 4.7 13.1 11 2 2 13 13 13 0 TATA element modulatory factor 1 DNA binding Ribosomal_S5_C PF03719.10 EMC91846.1 - 4.6e-17 61.0 0.1 1.1e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EMC91846.1 - 1.7e-09 37.3 0.1 1.7e-09 37.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Het-C PF07217.6 EMC91847.1 - 7e-268 889.8 0.0 8.6e-268 889.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C XAP5 PF04921.9 EMC91849.1 - 2.3e-70 236.8 0.0 3e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator Dicty_REP PF05086.7 EMC91849.1 - 0.98 7.0 7.0 1.4 6.6 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.6 EMC91849.1 - 7.2 4.3 10.0 0.22 9.3 2.4 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen HAD_2 PF13419.1 EMC91850.1 - 2.1e-10 41.0 0.0 3.9e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC91850.1 - 3.7e-06 26.5 0.0 7.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMC91850.1 - 1.5e-05 25.5 0.0 2.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Snf7 PF03357.16 EMC91851.1 - 1e-21 77.0 4.7 1.7e-21 76.3 3.2 1.3 1 0 0 1 1 1 1 Snf7 DUF1704 PF08014.6 EMC91851.1 - 0.025 13.5 0.6 0.044 12.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) GlnD_UR_UTase PF08335.6 EMC91851.1 - 0.026 14.3 1.2 0.15 11.9 0.1 2.5 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase DivIVA PF05103.8 EMC91851.1 - 6.8 6.7 9.0 6.5 6.8 3.0 2.7 2 1 1 3 3 3 0 DivIVA protein CS PF04969.11 EMC91852.1 - 1.5e-10 41.4 0.1 2.7e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 CS domain HSP20 PF00011.16 EMC91852.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family TPR_11 PF13414.1 EMC91853.1 - 7.2e-15 54.3 1.3 5.7e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMC91853.1 - 1.2e-09 37.3 0.0 0.00085 18.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC91853.1 - 3.3e-07 30.1 0.0 6.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC91853.1 - 5.5e-07 29.0 0.0 0.055 13.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC91853.1 - 0.00063 19.8 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMC91853.1 - 0.00082 18.9 0.0 2.1 8.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC91853.1 - 0.0026 18.2 0.9 0.75 10.6 0.0 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC91853.1 - 0.0091 16.3 0.0 0.0091 16.3 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC91853.1 - 0.014 15.1 0.0 0.32 10.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EMC91853.1 - 0.024 14.5 0.4 1.6 8.6 0.3 2.7 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EMC91853.1 - 0.1 13.0 0.1 35 5.1 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat RXT2_N PF08595.6 EMC91853.1 - 0.76 9.5 6.2 0.14 11.9 1.4 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal TT_ORF2 PF02957.10 EMC91853.1 - 1.6 9.4 10.6 0.073 13.7 1.3 2.6 3 0 0 3 3 3 0 TT viral ORF2 PBP1_TM PF14812.1 EMC91853.1 - 2.2 8.6 10.4 0.98 9.7 3.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EMC91853.1 - 9.2 4.8 13.8 0.2 10.3 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Mre11_DNA_bind PF04152.9 EMC91854.1 - 3e-52 177.0 0.9 3e-52 177.0 0.7 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EMC91854.1 - 5e-25 88.0 2.2 8.9e-25 87.2 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC91854.1 - 8.6e-06 25.6 0.1 2.7e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BsuBI_PstI_RE PF06616.6 EMC91854.1 - 0.028 13.2 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus Abhydrolase_3 PF07859.8 EMC91855.1 - 1.7e-51 174.8 0.1 2e-51 174.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMC91855.1 - 2.2e-05 23.3 0.4 7.3e-05 21.6 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMC91855.1 - 0.00045 20.0 0.0 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC91855.1 - 0.0013 17.9 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EMC91855.1 - 0.1 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) adh_short_C2 PF13561.1 EMC91857.1 - 5e-24 85.3 0.0 7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC91857.1 - 3.3e-20 72.6 0.1 4.3e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC91857.1 - 5.2e-09 36.0 0.1 7.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC91857.1 - 0.00031 20.2 0.1 0.00071 19.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC91857.1 - 0.0053 15.6 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EMC91857.1 - 0.0059 15.7 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EMC91857.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC91857.1 - 0.065 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 EMC91857.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 EMC91857.1 - 0.11 11.7 0.0 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family Laminin_EGF PF00053.19 EMC91859.1 - 0.095 12.6 0.6 0.28 11.1 0.4 1.8 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) tRNA_bind PF01588.15 EMC91860.1 - 3.2e-22 78.1 1.1 1.9e-21 75.7 0.1 2.4 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.1 EMC91860.1 - 3.1e-11 43.6 0.1 8.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC91860.1 - 4.8e-08 32.7 0.0 9.6e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC91860.1 - 1.2e-05 25.1 1.9 1.3e-05 25.1 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EMC91860.1 - 0.18 11.6 1.6 3.2 7.5 0.3 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain NUDIX PF00293.23 EMC91862.1 - 4.1e-27 94.4 0.0 5.9e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MCM PF00493.18 EMC91863.1 - 9e-135 448.7 0.6 1.3e-134 448.2 0.4 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMC91863.1 - 9.1e-21 74.5 0.2 4.6e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMC91863.1 - 3.3e-08 32.9 0.0 8.7e-07 28.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMC91863.1 - 0.00065 19.3 0.0 0.0039 16.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMC91863.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EMC91863.1 - 0.0095 15.6 0.0 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RRM_1 PF00076.17 EMC91864.1 - 1.2e-28 98.5 0.0 2.8e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC91864.1 - 1.4e-20 73.0 0.0 5.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC91864.1 - 1.4e-07 31.2 0.1 0.014 15.1 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ETC_C1_NDUFA4 PF04800.7 EMC91865.1 - 1.1e-36 124.6 2.4 1.5e-36 124.2 1.7 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 EMC91866.1 - 4.6e-35 119.7 0.1 5.1e-35 119.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EMC91866.1 - 0.0013 18.7 0.1 0.002 18.1 0.1 1.2 1 1 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Ammonium_transp PF00909.16 EMC91868.1 - 1.2e-110 369.7 22.3 1.4e-110 369.5 15.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FAD_binding_1 PF00667.15 EMC91869.1 - 7.5e-60 202.0 0.0 1.2e-59 201.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMC91869.1 - 9.9e-32 109.9 1.7 2.9e-31 108.3 1.2 1.9 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EMC91869.1 - 2.6e-23 82.6 0.1 2.2e-22 79.7 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EMC91869.1 - 0.063 13.2 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 Flavodoxin domain Acetyltransf_7 PF13508.1 EMC91870.1 - 3.2e-07 30.3 0.0 6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC91870.1 - 0.0029 17.6 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMC91870.1 - 0.01 15.9 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC91870.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EMC91870.1 - 0.099 12.5 0.1 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_1 PF00232.13 EMC91873.1 - 1.9e-102 342.8 0.6 2.2e-102 342.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 PPR_2 PF13041.1 EMC91874.1 - 4.6e-41 138.5 0.1 4.6e-09 36.1 0.0 12.9 10 2 4 14 14 14 11 PPR repeat family PPR_3 PF13812.1 EMC91874.1 - 6.5e-25 85.2 11.3 0.0068 16.6 0.0 13.7 15 0 0 15 15 15 5 Pentatricopeptide repeat domain PPR PF01535.15 EMC91874.1 - 9.2e-22 75.4 12.0 0.0025 17.6 0.1 13.4 17 0 0 17 17 17 4 PPR repeat PPR_1 PF12854.2 EMC91874.1 - 5.6e-19 67.3 0.0 5.5e-08 32.1 0.0 9.0 10 0 0 10 10 10 3 PPR repeat RPM2 PF08579.6 EMC91874.1 - 2.9e-08 33.8 0.0 7.6e-07 29.2 0.0 3.4 6 0 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EMC91874.1 - 0.13 11.6 0.0 0.63 9.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase expression TPR_14 PF13428.1 EMC91874.1 - 0.16 12.6 10.3 20 6.1 0.0 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 EMC91875.1 - 1.1e-15 57.4 1.4 2.8e-15 56.1 1.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMC91875.1 - 3.1e-09 36.8 0.0 8.2e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Amidohydro_2 PF04909.9 EMC91877.1 - 5.2e-51 173.8 0.0 6.1e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase adh_short_C2 PF13561.1 EMC91878.1 - 4.6e-25 88.7 0.2 5.5e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC91878.1 - 2.1e-22 79.7 0.2 2.1e-22 79.7 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMC91878.1 - 6.7e-09 35.6 0.5 2.6e-08 33.7 0.3 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC91878.1 - 1.7e-06 27.6 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PQ-loop PF04193.9 EMC91881.1 - 1e-19 69.7 10.7 2e-10 40.0 0.7 3.2 3 1 0 3 3 3 2 PQ loop repeat DUF4153 PF13687.1 EMC91881.1 - 8.5e-05 22.1 12.1 0.00025 20.6 5.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4153) ER_lumen_recept PF00810.13 EMC91881.1 - 0.051 14.0 1.7 0.14 12.6 0.5 2.2 2 1 1 3 3 3 0 ER lumen protein retaining receptor YajC PF02699.10 EMC91881.1 - 0.14 11.8 0.3 1.4 8.6 0.4 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit DUF4131 PF13567.1 EMC91881.1 - 3.3 7.0 18.2 3.8 6.8 0.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) UNC45-central PF11701.3 EMC91882.1 - 8.6e-30 103.4 4.5 4.4e-29 101.1 0.2 3.4 2 1 0 3 3 3 1 Myosin-binding striated muscle assembly central PaaX PF07848.7 EMC91882.1 - 0.057 13.4 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 PaaX-like protein TPR_11 PF13414.1 EMC91882.1 - 0.068 12.8 2.0 9 6.0 0.1 3.4 3 0 0 3 3 3 0 TPR repeat Ferritin_2 PF13668.1 EMC91883.1 - 0.00059 19.7 0.0 0.00098 19.0 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain MFS_1 PF07690.11 EMC91884.1 - 2.4e-19 69.2 51.9 2.5e-11 42.9 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEN-2 PF10251.4 EMC91884.1 - 0.002 18.2 1.8 0.13 12.5 0.0 2.8 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase DUF1228 PF06779.9 EMC91884.1 - 2.7 8.0 12.2 0.31 11.0 0.6 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) CPSase_L_D2 PF02786.12 EMC91885.1 - 1.9e-112 373.6 0.1 7.7e-84 280.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EMC91885.1 - 1.7e-45 154.8 0.0 3.5e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EMC91885.1 - 1.9e-42 143.8 0.0 4.1e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 EMC91885.1 - 6.2e-42 142.6 0.0 1.2e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EMC91885.1 - 2.1e-41 140.5 0.1 4.1e-41 139.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EMC91885.1 - 4.2e-40 136.2 0.0 1.7e-18 66.6 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EMC91885.1 - 9.1e-38 129.8 0.1 2.1e-20 73.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EMC91885.1 - 4.3e-35 120.9 0.1 1.1e-34 119.6 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EMC91885.1 - 3.4e-23 81.9 0.2 1.6e-09 36.9 0.0 4.7 4 1 0 4 4 4 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EMC91885.1 - 5e-18 64.8 0.0 2.9e-17 62.3 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EMC91885.1 - 5e-17 61.9 0.2 3.4e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMC91885.1 - 5.7e-16 58.3 0.0 7e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EMC91885.1 - 1.1e-07 31.8 0.1 0.0057 16.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EMC91885.1 - 5.9e-06 25.8 0.0 0.0025 17.3 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 EMC91885.1 - 1e-05 25.1 0.1 0.00044 19.7 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EMC91885.1 - 0.0031 16.9 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 EMC91885.1 - 0.0062 16.1 0.1 0.83 9.1 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HET PF06985.6 EMC91886.1 - 1.7e-30 106.0 1.8 2.9e-30 105.2 1.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4336 PF14234.1 EMC91890.1 - 0.012 14.8 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Abhydrolase_3 PF07859.8 EMC91891.1 - 1.2e-37 129.5 0.0 1.6e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC91891.1 - 0.066 12.4 0.0 10 5.2 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 EMC91891.1 - 0.21 10.2 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family HD PF01966.17 EMC91892.1 - 6.3e-07 29.4 0.3 1e-06 28.7 0.2 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 EMC91892.1 - 5.9e-05 22.4 0.1 0.00014 21.2 0.0 1.6 1 1 1 2 2 2 1 HDOD domain HD_4 PF13328.1 EMC91892.1 - 0.0029 17.3 0.1 0.0048 16.6 0.1 1.3 1 0 0 1 1 1 1 HD domain DUF706 PF05153.10 EMC91892.1 - 0.0051 16.1 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) DUF732 PF05305.9 EMC91892.1 - 0.052 13.6 0.1 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Pyr_redox_3 PF13738.1 EMC91893.1 - 1.5e-16 61.0 0.0 3.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC91893.1 - 3.8e-09 36.7 0.0 3.3e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC91893.1 - 5.1e-08 32.8 0.0 9.4e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EMC91893.1 - 5.5e-08 31.4 0.0 8.4e-08 30.8 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMC91893.1 - 1.1e-05 24.5 0.0 0.0003 19.8 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EMC91893.1 - 1.3e-05 24.3 0.0 9.1e-05 21.5 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EMC91893.1 - 0.0014 17.5 0.4 0.39 9.5 0.1 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC91893.1 - 0.01 15.5 0.2 0.094 12.4 0.0 2.7 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMC91893.1 - 0.013 15.8 0.0 7.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC91893.1 - 0.094 11.7 2.1 0.11 11.5 0.0 2.0 3 0 0 3 3 3 0 Thi4 family PhyH PF05721.8 EMC91894.1 - 6.2e-24 85.2 0.0 8.5e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EMC91894.1 - 0.0018 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EMC91894.1 - 0.0093 16.4 0.0 0.018 15.5 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 EMC91895.1 - 2.6e-37 128.5 36.5 2.6e-24 85.6 8.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC91895.1 - 5.9e-27 94.2 57.8 5.3e-19 68.1 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.11 EMC91895.1 - 0.7 8.9 3.4 0.98 8.4 0.7 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family zf-HIT PF04438.11 EMC91896.1 - 6.4e-09 35.2 13.3 1.1e-08 34.6 9.2 1.4 1 0 0 1 1 1 1 HIT zinc finger DENN PF02141.16 EMC91897.1 - 2.8e-39 134.7 0.1 4.6e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EMC91897.1 - 0.00048 20.0 0.1 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.6 EMC91897.1 - 0.015 15.6 5.7 0.015 15.6 3.9 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-RING_5 PF14634.1 EMC91898.1 - 5.1e-08 32.5 5.8 8.8e-08 31.7 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC91898.1 - 3.4e-05 23.7 2.9 6.7e-05 22.8 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC91898.1 - 0.00027 20.7 5.1 0.00052 19.7 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC91898.1 - 0.00051 19.6 5.4 0.00097 18.7 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC91898.1 - 0.0036 16.9 5.5 0.0064 16.1 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tweety PF04906.8 EMC91898.1 - 0.0059 15.0 0.9 0.0065 14.9 0.1 1.4 1 1 0 1 1 1 1 Tweety ATG16 PF08614.6 EMC91898.1 - 0.0061 16.4 4.9 0.0089 15.8 3.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 EMC91898.1 - 0.018 14.7 5.3 0.027 14.1 3.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DZR PF12773.2 EMC91898.1 - 0.028 14.2 2.8 0.078 12.8 1.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF972 PF06156.8 EMC91898.1 - 0.029 14.7 3.5 0.048 14.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) zf-C3HC4_4 PF15227.1 EMC91898.1 - 0.033 14.0 3.7 0.06 13.2 2.3 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1896 PF08989.5 EMC91898.1 - 0.056 13.3 0.2 0.2 11.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1896) CENP-H PF05837.7 EMC91898.1 - 0.062 13.4 4.9 0.11 12.6 3.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-rbx1 PF12678.2 EMC91898.1 - 0.063 13.3 3.2 0.58 10.3 1.3 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger APG6 PF04111.7 EMC91898.1 - 0.19 10.7 6.4 0.32 9.9 4.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EMC91898.1 - 0.25 9.7 3.5 0.31 9.4 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DNA_ligase_ZBD PF03119.11 EMC91898.1 - 0.26 11.0 0.2 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Syntaxin PF00804.20 EMC91898.1 - 0.27 11.4 5.3 0.44 10.7 3.7 1.4 1 0 0 1 1 1 0 Syntaxin zf-MIZ PF02891.15 EMC91898.1 - 0.32 10.5 3.1 0.63 9.6 2.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger OmpH PF03938.9 EMC91898.1 - 0.33 10.8 10.8 0.49 10.3 7.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-RING_6 PF14835.1 EMC91898.1 - 0.34 10.7 7.4 0.65 9.8 5.1 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Fzo_mitofusin PF04799.8 EMC91898.1 - 0.41 10.0 3.4 0.62 9.4 2.0 1.5 1 1 0 1 1 1 0 fzo-like conserved region C1_4 PF07975.7 EMC91898.1 - 0.91 9.5 4.6 9.6 6.2 2.1 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain IncA PF04156.9 EMC91898.1 - 0.91 9.0 7.4 1.3 8.5 5.1 1.2 1 0 0 1 1 1 0 IncA protein FYVE PF01363.16 EMC91898.1 - 1.8 8.4 5.8 3.8 7.4 4.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger Ribosomal_S19 PF00203.16 EMC91899.1 - 2.5e-23 81.4 0.0 3.7e-23 80.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 Cep57_MT_bd PF06657.8 EMC91900.1 - 0.034 14.0 0.1 0.097 12.6 0.1 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 adh_short PF00106.20 EMC91901.1 - 2.1e-13 50.5 0.2 1.7e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMC91901.1 - 6.8e-08 32.3 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC91901.1 - 0.00024 20.9 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC91901.1 - 0.00045 19.7 0.3 0.0027 17.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC91901.1 - 0.036 14.0 0.6 0.07 13.1 0.4 1.6 1 1 0 1 1 1 0 NADH(P)-binding ABC_tran PF00005.22 EMC91902.1 - 6.9e-20 71.7 0.0 3.5e-10 40.3 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMC91902.1 - 1.9e-07 31.3 1.1 0.021 14.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EMC91902.1 - 3.9e-05 23.4 0.1 0.11 12.4 0.1 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EMC91902.1 - 0.02 15.2 0.8 0.034 14.4 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC91902.1 - 0.038 13.5 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EMC91902.1 - 0.051 13.7 0.2 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EMC91902.1 - 0.065 11.6 0.0 0.091 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMC91902.1 - 0.088 12.2 0.0 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EMC91902.1 - 0.089 12.1 2.5 2.6 7.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain NAD_binding_2 PF03446.10 EMC91903.1 - 3.3e-39 134.3 0.1 5.2e-39 133.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMC91903.1 - 1.6e-28 99.2 0.1 1.4e-26 92.9 0.0 2.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMC91903.1 - 2.3e-05 24.7 0.0 5.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.14 EMC91903.1 - 0.0017 18.7 0.1 0.0038 17.7 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 EMC91903.1 - 0.0028 18.1 0.0 0.0054 17.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EMC91903.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Receptor_IA-2 PF11548.3 EMC91903.1 - 0.13 12.2 0.2 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 TRAPPC-Trs85 PF12739.2 EMC91905.1 - 2.2e-110 369.1 1.4 7.6e-110 367.3 1.1 1.6 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2454 PF10521.4 EMC91906.1 - 3.9e-54 183.5 1.9 1e-53 182.1 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EMC91906.1 - 5e-22 78.4 2.7 2.5e-21 76.1 1.9 2.2 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EMC91906.1 - 1.5e-06 27.6 0.0 4.8e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EMC91906.1 - 0.005 16.6 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Fungal_trans PF04082.13 EMC91907.1 - 5.8e-44 149.9 0.0 8.7e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC91907.1 - 1.2e-08 34.6 7.6 2.5e-08 33.6 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EMC91907.1 - 0.18 9.9 5.9 0.28 9.3 4.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.7 EMC91907.1 - 1.7 6.2 2.6 2.5 5.7 1.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein bZIP_1 PF00170.16 EMC91909.1 - 0.018 14.9 6.0 0.018 14.9 4.1 2.0 1 1 1 2 2 2 0 bZIP transcription factor ADSL_C PF10397.4 EMC91909.1 - 0.051 13.5 0.6 0.071 13.1 0.1 1.5 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus AAA_27 PF13514.1 EMC91909.1 - 0.13 9.9 3.9 0.14 9.7 2.7 1.0 1 0 0 1 1 1 0 AAA domain SpoIIIAH PF12685.2 EMC91909.1 - 0.16 11.4 0.9 0.18 11.3 0.6 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein HSCB_C PF07743.8 EMC91909.1 - 0.19 12.2 1.8 0.23 11.9 1.3 1.2 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF2385 PF09539.5 EMC91909.1 - 0.48 10.8 2.6 0.53 10.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) DUF3435 PF11917.3 EMC91909.1 - 1.2 7.7 4.9 1.4 7.5 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF883 PF05957.8 EMC91909.1 - 1.4 9.3 5.4 1.9 8.9 3.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) bZIP_2 PF07716.10 EMC91909.1 - 4.3 7.2 10.0 0.62 9.9 3.0 2.1 1 1 1 2 2 2 0 Basic region leucine zipper TPR_12 PF13424.1 EMC91910.1 - 2.4e-27 94.6 18.2 3.5e-10 39.6 1.3 4.6 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EMC91910.1 - 2.9e-21 74.6 10.9 2.5e-06 27.2 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat HET PF06985.6 EMC91910.1 - 6.6e-18 65.2 6.5 1.8e-15 57.3 0.8 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_19 PF14559.1 EMC91910.1 - 8.1e-12 45.3 15.8 3.8e-06 27.1 1.0 5.9 3 1 3 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 EMC91910.1 - 3.7e-11 42.4 0.3 6.8e-11 41.5 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 EMC91910.1 - 9.3e-10 38.5 1.7 2.6e-05 24.2 0.1 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EMC91910.1 - 1.1e-09 37.7 10.9 0.0022 18.2 0.1 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EMC91910.1 - 2.7e-09 36.8 6.9 0.17 12.4 0.3 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC91910.1 - 3e-09 36.7 11.3 0.0025 18.3 1.8 6.5 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC91910.1 - 3.6e-09 37.0 8.9 9.9e-07 29.2 1.6 4.1 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC91910.1 - 4.3e-09 35.8 1.1 0.024 14.8 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC91910.1 - 3e-07 29.8 5.2 0.075 12.9 0.1 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_22 PF13401.1 EMC91910.1 - 3.6e-07 30.3 0.9 1.6e-06 28.2 0.0 2.5 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMC91910.1 - 4.7e-07 29.9 0.9 1.8e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain TPR_11 PF13414.1 EMC91910.1 - 3.6e-06 26.5 3.3 0.012 15.2 0.3 4.3 3 1 1 4 4 4 2 TPR repeat TPR_20 PF14561.1 EMC91910.1 - 7.9e-06 25.9 13.3 0.67 10.1 0.2 5.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC91910.1 - 9.3e-05 21.9 5.9 15 5.6 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC91910.1 - 0.00017 21.1 4.2 2.2 8.2 0.1 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC91910.1 - 0.004 16.7 4.1 12 5.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 EMC91910.1 - 0.0056 16.5 0.1 4.9 7.3 0.0 4.8 5 0 0 5 5 4 1 PPR repeat TPR_21 PF09976.4 EMC91910.1 - 0.0087 16.0 6.5 0.2 11.6 0.2 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.26 EMC91911.1 - 7.9e-17 60.7 0.9 2.6e-16 59.1 0.6 2.0 1 0 0 1 1 1 1 DnaJ domain AAA_11 PF13086.1 EMC91911.1 - 0.36 10.3 3.1 0.61 9.6 2.1 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EMC91912.1 - 1e-42 145.4 0.0 1.9e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMC91912.1 - 3.2e-24 84.2 0.1 6.9e-24 83.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMC91912.1 - 8.3e-23 80.0 0.0 1.9e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EMC91912.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.1 EMC91912.1 - 0.041 12.9 0.0 0.041 12.9 0.0 4.4 6 0 0 6 6 6 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 EMC91912.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DNA_mis_repair PF01119.14 EMC91913.1 - 4.3e-33 113.2 0.1 7.4e-33 112.5 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EMC91913.1 - 6e-14 51.8 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMC91913.1 - 1.1e-10 41.1 0.0 3.3e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peroxidase_2 PF01328.12 EMC91914.1 - 3.2e-17 62.2 2.6 8.9e-17 60.7 1.8 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 Na_Ca_ex PF01699.19 EMC91915.1 - 2.1e-43 147.2 34.6 4e-23 81.5 7.6 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EMC91915.1 - 0.026 14.3 6.6 0.1 12.4 0.0 3.8 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Oligomerisation PF02410.10 EMC91917.1 - 3.1e-05 23.9 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 2 Oligomerisation domain DUF924 PF06041.6 EMC91918.1 - 4.4e-31 108.0 0.2 7.7e-31 107.2 0.2 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF2306 PF10067.4 EMC91919.1 - 4.3e-12 46.0 9.3 1.5e-11 44.3 6.4 1.9 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) IncA PF04156.9 EMC91919.1 - 0.022 14.3 1.9 0.049 13.2 0.9 1.8 2 0 0 2 2 2 0 IncA protein PrgI PF12666.2 EMC91919.1 - 3 8.0 9.2 0.3 11.2 1.6 2.9 2 1 1 3 3 3 0 PrgI family protein Glycos_transf_1 PF00534.15 EMC91920.1 - 5.3e-29 100.8 0.0 2.7e-27 95.2 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMC91920.1 - 4.5e-09 36.5 0.0 4.1e-06 26.9 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMC91920.1 - 1.3e-08 34.7 0.0 9.7e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EMC91920.1 - 2.7e-07 30.7 0.0 5.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMC91920.1 - 6.7e-06 26.3 0.0 2.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Asp PF00026.18 EMC91921.1 - 3e-44 151.5 0.3 3.9e-44 151.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EMC91921.1 - 0.0001 22.7 0.3 0.21 12.1 0.2 3.5 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMC91921.1 - 0.022 14.2 0.1 2.4 7.7 0.0 2.7 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal RRM_1 PF00076.17 EMC91922.1 - 1.5e-14 53.3 0.0 2.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC91922.1 - 1.1e-13 50.9 0.0 1.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC91922.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EMC91922.1 - 0.00065 20.0 2.5 0.00065 20.0 1.7 3.3 2 2 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Aldedh PF00171.17 EMC91923.1 - 1.2e-189 630.4 1.1 1.4e-189 630.2 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMC91923.1 - 0.13 11.4 0.2 0.94 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF3533 PF12051.3 EMC91924.1 - 1.9e-110 369.2 14.6 2.2e-110 369.0 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) VirB8 PF04335.8 EMC91924.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 VirB8 protein Oxidored_FMN PF00724.15 EMC91925.1 - 1.8e-43 148.8 0.0 3.1e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_C37 PF05416.7 EMC91928.1 - 0.9 7.7 5.0 1.1 7.4 3.4 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase IPK PF03770.11 EMC91930.1 - 5.9e-59 199.0 0.3 2.7e-58 196.8 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase DUF2360 PF10152.4 EMC91930.1 - 0.14 12.3 1.8 0.33 11.2 1.3 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) tRNA_U5-meth_tr PF05958.6 EMC91931.1 - 1.8e-14 53.2 0.0 1.3e-13 50.3 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EMC91931.1 - 9.4e-09 35.0 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC91931.1 - 1.1e-06 28.6 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EMC91931.1 - 1.3e-06 28.0 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRAM PF01938.15 EMC91931.1 - 7e-05 22.5 0.1 0.0003 20.5 0.0 2.1 2 0 0 2 2 2 1 TRAM domain Methyltransf_18 PF12847.2 EMC91931.1 - 0.0001 22.8 0.0 0.00021 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC91931.1 - 0.00016 20.8 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EMC91931.1 - 0.00019 21.7 0.0 0.00084 19.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC91931.1 - 0.00087 19.7 0.0 0.0023 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EMC91931.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 EMC91931.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EMC91931.1 - 0.0094 16.4 0.0 0.029 14.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMC91931.1 - 0.038 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TRM PF02005.11 EMC91931.1 - 0.065 12.1 0.1 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_32 PF13679.1 EMC91931.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EMC91932.1 - 4.4e-33 114.4 27.3 4.4e-33 114.4 18.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily NAD_binding_9 PF13454.1 EMC91933.1 - 0.14 11.9 0.8 0.32 10.7 0.6 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.3 EMC91934.1 - 8.6e-12 44.3 1.7 4.4e-11 42.0 1.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC91934.1 - 7.1e-07 29.0 12.7 1.2e-06 28.3 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syja_N PF02383.13 EMC91935.1 - 5e-87 291.6 0.0 1.4e-86 290.1 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain DNA_pol_delta_4 PF04081.8 EMC91936.1 - 7.2e-25 87.6 7.1 1.6e-23 83.3 4.9 2.1 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DcpS_C PF11969.3 EMC91937.1 - 8.7e-28 96.8 0.1 1.3e-27 96.2 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EMC91937.1 - 1.9e-25 89.4 0.0 3.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal ECH PF00378.15 EMC91938.1 - 5.4e-45 153.4 0.2 6.7e-44 149.8 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EMC91938.1 - 0.0055 16.5 0.1 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family S49 Condensation PF00668.15 EMC91939.1 - 7.5e-12 44.7 1.4 1.5e-10 40.3 1.0 2.0 1 1 0 1 1 1 1 Condensation domain AMP-binding PF00501.23 EMC91940.1 - 5.5e-77 258.9 0.0 7.3e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC91940.1 - 1.6e-14 54.5 0.2 4.3e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EMC91940.1 - 0.02 13.4 0.0 0.062 11.8 0.0 1.7 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DUF4342 PF14242.1 EMC91940.1 - 0.13 12.0 3.5 38 4.1 0.3 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4342) GATase PF00117.23 EMC91942.1 - 1.7e-10 40.6 0.0 2.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMC91942.1 - 0.057 12.8 0.1 0.59 9.5 0.1 2.4 1 1 0 1 1 1 0 Peptidase C26 GDA1_CD39 PF01150.12 EMC91943.1 - 2.4e-103 345.9 0.0 3.5e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family KA1 PF02149.14 EMC91943.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase associated domain 1 KGG PF10685.4 EMC91944.1 - 1.2e-19 69.7 15.5 5.1e-10 39.0 0.6 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif LEA_5 PF00477.12 EMC91944.1 - 0.0058 16.8 3.3 0.007 16.6 2.3 1.2 1 0 0 1 1 1 1 Small hydrophilic plant seed protein adh_short PF00106.20 EMC91945.1 - 8e-34 116.9 0.0 1.1e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC91945.1 - 2.6e-14 53.5 0.0 3.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC91945.1 - 7.2e-14 51.8 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMC91945.1 - 0.00032 19.7 0.1 0.0031 16.4 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EMC91945.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMC91945.1 - 0.0072 16.0 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EMC91945.1 - 0.046 12.8 1.1 2.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_4 PF07993.7 EMC91945.1 - 0.053 12.4 0.0 0.12 11.3 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein ADH_zinc_N PF00107.21 EMC91946.1 - 1e-28 99.4 0.0 1.7e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC91946.1 - 2.1e-13 51.2 0.0 3.9e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC91946.1 - 8.5e-09 35.1 0.0 3.6e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1564 PF07600.6 EMC91946.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Arb1 PF09692.5 EMC91947.1 - 6.4e-94 315.0 0.0 8.3e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.12 EMC91947.1 - 6.5e-13 48.2 0.1 2.3e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 La domain IPK PF03770.11 EMC91948.1 - 4.1e-53 179.9 0.0 5.5e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Peptidase_M75 PF09375.5 EMC91948.1 - 0.015 14.6 0.1 0.032 13.5 0.0 1.5 1 1 0 1 1 1 0 Imelysin DUF4055 PF13264.1 EMC91948.1 - 0.049 13.7 0.1 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Dsl1_N PF11988.3 EMC91948.1 - 0.074 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal DUF2384 PF09722.5 EMC91948.1 - 0.089 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) CoA_transf_3 PF02515.12 EMC91949.1 - 1.3e-59 200.6 0.0 1.7e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Clp1 PF06807.9 EMC91950.1 - 7.1e-22 78.1 0.0 1.3e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EMC91950.1 - 1.6e-06 27.8 0.0 4.1e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EMC91950.1 - 3.2e-05 23.9 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EMC91950.1 - 0.00017 21.4 0.0 0.76 9.5 0.0 2.6 3 0 0 3 3 3 2 Dynamin family ATP_bind_1 PF03029.12 EMC91950.1 - 0.0004 20.0 0.0 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EMC91950.1 - 0.00072 19.5 0.0 0.005 16.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EMC91950.1 - 0.045 13.2 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 EMC91950.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Ion_trans PF00520.26 EMC91951.1 - 1.1e-06 28.0 8.9 1.1e-06 28.0 6.2 2.7 2 1 1 3 3 3 1 Ion transport protein DUF3814 PF12769.2 EMC91951.1 - 0.4 10.8 4.0 0.12 12.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) zf-C2H2 PF00096.21 EMC91952.1 - 2.9e-11 43.0 14.3 0.00088 19.4 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC91952.1 - 8.3e-10 38.3 12.5 0.0045 17.2 1.0 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC91952.1 - 1e-05 25.5 14.6 0.0086 16.3 1.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EMC91952.1 - 0.00045 20.3 1.8 3.2 8.0 0.4 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC91952.1 - 0.0006 19.8 8.1 0.081 13.0 0.6 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC91952.1 - 0.032 14.1 3.3 3 7.8 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 EMC91952.1 - 0.062 13.0 6.0 0.075 12.8 0.9 2.7 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 EMC91952.1 - 3.9 7.6 8.4 1.5 8.9 1.9 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 EMC91952.1 - 8.9 5.9 9.3 2.7 7.6 0.3 3.5 3 1 1 4 4 4 0 GAGA factor DUF3795 PF12675.2 EMC91953.1 - 0.0052 16.9 3.9 0.0076 16.3 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3795) Herpes_glycop_D PF01537.12 EMC91953.1 - 0.052 13.5 1.4 0.062 13.2 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain zf-MYND PF01753.13 EMC91953.1 - 1.8 8.4 7.9 8.9 6.2 1.8 2.8 1 1 1 2 2 2 0 MYND finger PI31_Prot_N PF11566.3 EMC91955.1 - 1.5e-33 115.5 0.0 1.9e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EMC91955.1 - 5.8e-16 58.8 18.7 5.8e-16 58.8 13.0 3.0 3 0 0 3 3 3 1 PI31 proteasome regulator zf-RING_5 PF14634.1 EMC91958.1 - 7.7e-09 35.1 10.7 7.7e-09 35.1 7.4 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC91958.1 - 1.5e-08 34.1 9.9 3e-08 33.1 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC91958.1 - 1.5e-08 34.4 10.2 3e-08 33.5 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC91958.1 - 1.7e-07 30.9 10.8 3.8e-07 29.8 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC91958.1 - 1.6e-06 27.6 7.9 3.2e-06 26.6 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EMC91958.1 - 9.3e-06 25.3 2.6 1.6e-05 24.6 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EMC91958.1 - 9.7e-06 25.3 9.2 2.1e-05 24.2 6.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Mob_synth_C PF06463.8 EMC91958.1 - 6.7e-05 22.5 1.0 0.00017 21.2 0.7 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_UBOX PF13445.1 EMC91958.1 - 8.5e-05 22.1 6.0 0.00023 20.7 4.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger SAP PF02037.22 EMC91958.1 - 0.001 18.5 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_4 PF14570.1 EMC91958.1 - 0.0025 17.3 7.3 0.036 13.6 5.5 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EMC91958.1 - 0.0056 16.7 6.7 0.017 15.2 4.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-P11 PF03854.9 EMC91958.1 - 0.0094 15.4 3.9 0.026 13.9 2.7 1.7 1 0 0 1 1 1 1 P-11 zinc finger U-box PF04564.10 EMC91958.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-Apc11 PF12861.2 EMC91958.1 - 0.032 14.0 1.9 0.1 12.4 1.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EMC91958.1 - 0.25 11.2 7.4 0.68 9.8 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Snf7 PF03357.16 EMC91959.1 - 2.6e-21 75.7 20.0 5e-21 74.8 13.9 1.4 1 0 0 1 1 1 1 Snf7 SKIP_SNW PF02731.10 EMC91959.1 - 6.3 6.2 12.3 0.58 9.6 2.2 2.4 2 0 0 2 2 2 0 SKIP/SNW domain Thioredoxin PF00085.15 EMC91960.1 - 1.4e-28 98.5 0.1 1.6e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMC91960.1 - 2.8e-06 27.5 0.6 6e-05 23.2 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC91960.1 - 0.00014 21.8 0.0 0.0032 17.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EMC91960.1 - 0.0013 18.2 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Disulph_isomer PF06491.6 EMC91960.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.8 1 1 0 1 1 1 0 Disulphide isomerase Thioredoxin_7 PF13899.1 EMC91960.1 - 0.038 13.9 0.4 0.068 13.1 0.3 1.6 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 EMC91960.1 - 0.075 12.7 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Phosducin PF02114.11 EMC91960.1 - 0.086 11.5 0.0 0.094 11.4 0.0 1.0 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.5 EMC91960.1 - 0.14 11.6 0.2 0.43 10.1 0.2 1.6 1 1 1 2 2 2 0 Redoxin KilA-N PF04383.8 EMC91961.1 - 0.0018 17.8 0.0 0.032 13.8 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Rho_GDI PF02115.12 EMC91962.1 - 2.9e-56 190.0 0.2 3.4e-56 189.8 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Fumerase_C PF05683.7 EMC91962.1 - 0.012 14.7 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Fumarase C-terminus WD40 PF00400.27 EMC91963.1 - 8.8e-05 22.2 0.0 0.13 12.1 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMC91963.1 - 0.015 14.7 0.0 21 4.6 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.10 EMC91963.1 - 0.055 12.5 0.0 0.69 8.9 0.0 2.4 3 0 0 3 3 3 0 CPSF A subunit region Coatomer_WDAD PF04053.9 EMC91963.1 - 0.063 12.0 0.0 0.64 8.7 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region zf-PHD-like PF15446.1 EMC91963.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Cupin_8 PF13621.1 EMC91964.1 - 7e-40 137.0 0.0 1.4e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 EMC91964.1 - 1.6e-21 76.7 0.0 2.8e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EMC91964.1 - 3.3e-08 33.1 12.9 0.007 16.1 0.2 5.5 4 1 1 5 5 5 4 Galactose oxidase, central domain Cupin_4 PF08007.7 EMC91964.1 - 6.1e-08 32.2 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.1 EMC91964.1 - 4.9e-06 26.3 0.3 0.0081 16.1 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EMC91964.1 - 0.00032 20.7 5.9 0.44 10.7 0.1 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain HisKA PF00512.20 EMC91964.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DSPc PF00782.15 EMC91965.1 - 1.2e-30 105.7 0.0 1.9e-21 76.0 0.0 2.7 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC91965.1 - 1.6e-07 30.9 0.0 7.9e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC91965.1 - 0.0036 17.3 0.2 0.088 12.8 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.7 EMC91965.1 - 0.052 13.0 1.9 3.7 6.9 0.0 2.9 3 1 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) NUC205 PF08168.6 EMC91965.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 NUC205 domain adh_short PF00106.20 EMC91966.1 - 5.5e-21 75.1 0.2 7.7e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC91966.1 - 1.2e-12 48.1 0.0 1.5e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC91966.1 - 4.2e-12 46.0 0.0 6.1e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC91966.1 - 2.6e-05 24.2 0.1 9e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC91966.1 - 9.8e-05 21.8 0.0 0.00037 19.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC91966.1 - 0.022 13.6 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein URO-D PF01208.12 EMC91966.1 - 0.092 11.6 0.1 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) MoeA_N PF03453.12 EMC91967.1 - 1.7e-36 124.9 1.5 2.5e-36 124.4 1.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 EMC91967.1 - 8.6e-33 112.7 0.2 5.1e-28 97.2 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.10 EMC91967.1 - 1.1e-17 63.7 0.0 3.1e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ATP-synt_C PF00137.16 EMC91968.1 - 4.1e-28 97.0 20.8 9.6e-16 57.4 5.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C TFIIA_gamma_C PF02751.9 EMC91969.1 - 8.2e-27 92.7 1.2 1.1e-26 92.3 0.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EMC91969.1 - 8.9e-24 82.8 0.1 1.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain UPF0546 PF10639.4 EMC91970.1 - 0.0033 17.2 2.1 0.0042 16.8 1.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 EMC91970.1 - 0.0039 17.3 4.3 0.007 16.5 3.0 1.4 1 0 0 1 1 1 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC91970.1 - 0.013 15.5 11.9 0.023 14.7 8.3 1.5 1 1 0 1 1 1 0 EamA-like transporter family TPT PF03151.11 EMC91970.1 - 0.042 13.4 7.8 0.053 13.1 4.9 1.4 1 1 0 1 1 1 0 Triose-phosphate Transporter family Git3 PF11710.3 EMC91971.1 - 1.9e-51 174.5 13.0 1.9e-51 174.5 9.0 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EMC91971.1 - 7.5e-27 92.9 3.8 1.8e-26 91.6 2.7 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Peptidase_C12 PF01088.16 EMC91972.1 - 1.7e-62 210.4 0.0 2.1e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Epimerase PF01370.16 EMC91973.1 - 6.4e-47 159.9 0.0 8.9e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EMC91973.1 - 5e-27 93.6 0.1 1e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EMC91973.1 - 2.5e-18 65.7 0.0 3.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMC91973.1 - 5.2e-15 55.1 0.0 3.4e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMC91973.1 - 1.8e-13 50.0 0.0 2.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMC91973.1 - 3.9e-13 49.6 0.0 6.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMC91973.1 - 5.6e-09 36.2 0.0 9.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMC91973.1 - 1.5e-08 34.5 0.0 3e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EMC91973.1 - 6.8e-08 31.7 0.0 7e-07 28.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein DAO PF01266.19 EMC91973.1 - 0.014 14.3 0.0 0.036 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NmrA PF05368.8 EMC91973.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EMC91973.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.1 EMC91973.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sad1_UNC PF07738.8 EMC91974.1 - 2e-07 30.8 0.1 0.0068 16.2 0.0 2.6 2 1 1 3 3 3 2 Sad1 / UNC-like C-terminal HET PF06985.6 EMC91975.1 - 1.6e-13 51.0 0.0 2.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP_bind_1 PF03029.12 EMC91976.1 - 1.3e-59 201.6 0.0 1.9e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EMC91976.1 - 0.00029 21.6 0.0 0.0015 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC91976.1 - 0.0034 17.3 0.0 0.035 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EMC91976.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EMC91976.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMC91976.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EMC91976.1 - 0.03 14.6 0.0 0.081 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EMC91976.1 - 0.041 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 EMC91976.1 - 0.058 12.8 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 EMC91976.1 - 0.062 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain FAD_binding_8 PF08022.7 EMC91977.1 - 8e-19 67.4 0.0 1.7e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMC91977.1 - 1.9e-16 60.3 0.0 3.3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMC91977.1 - 1e-09 38.5 4.3 1e-09 38.5 3.0 2.2 1 1 2 3 3 3 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.1 EMC91977.1 - 5.2e-05 23.3 0.2 0.00016 21.7 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC91977.1 - 5.8e-05 22.6 0.3 0.00011 21.7 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC91977.1 - 0.00048 19.2 0.2 0.001 18.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EMC91977.1 - 0.00058 19.5 0.1 0.0017 18.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain FAD_binding_6 PF00970.19 EMC91977.1 - 0.0013 18.8 0.0 0.0043 17.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain EF-hand_5 PF13202.1 EMC91977.1 - 0.0028 16.9 0.1 0.0057 15.9 0.1 1.5 1 0 0 1 1 1 1 EF hand DUF3828 PF12883.2 EMC91978.1 - 0.1 12.5 0.0 4.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3828) FAD_binding_3 PF01494.14 EMC91980.1 - 2.4e-71 240.6 0.0 3.1e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC91980.1 - 0.0005 20.1 0.0 0.00098 19.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 4HBT PF03061.17 EMC91981.1 - 7.5e-08 32.3 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EMC91981.1 - 0.00041 19.3 0.2 0.00055 18.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 EMC91981.1 - 0.018 15.4 0.0 0.025 15.0 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily ADH_N PF08240.7 EMC91982.1 - 6.2e-29 99.9 1.5 1e-28 99.2 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC91982.1 - 1.4e-11 44.0 0.0 3.1e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.16 EMC91982.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_3 PF13738.1 EMC91982.1 - 0.15 12.1 0.2 0.47 10.4 0.1 1.8 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 EMC91983.1 - 3.2e-14 53.2 13.3 8.1e-12 45.4 4.6 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 EMC91984.1 - 9e-20 69.7 3.0 4.5e-06 26.3 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat NUC153 PF08159.7 EMC91985.1 - 6.5e-16 57.6 12.6 2.9e-13 49.1 0.6 3.6 3 0 0 3 3 3 3 NUC153 domain CBFD_NFYB_HMF PF00808.18 EMC91986.1 - 1.8e-12 47.1 0.1 4e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC91986.1 - 4.6e-05 23.4 0.2 6.6e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Adeno_E4 PF05385.6 EMC91986.1 - 0.11 12.4 0.1 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein TAFII28 PF04719.9 EMC91986.1 - 0.13 12.0 0.1 0.13 12.0 0.1 1.7 2 0 0 2 2 2 0 hTAFII28-like protein conserved region DUF3708 PF12501.3 EMC91986.1 - 0.17 11.7 2.2 0.22 11.3 1.5 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter GAGA_bind PF06217.7 EMC91986.1 - 0.2 11.6 1.8 0.24 11.3 1.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Muted PF14942.1 EMC91986.1 - 0.39 10.5 5.7 0.68 9.8 4.0 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein PPP4R2 PF09184.6 EMC91986.1 - 2.6 7.5 14.3 4 6.9 9.9 1.4 1 0 0 1 1 1 0 PPP4R2 RNase_PH PF01138.16 EMC91987.1 - 1.3e-26 93.4 0.0 2.5e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 OTT_1508_deam PF14441.1 EMC91990.1 - 7.5e-15 54.9 1.4 9.9e-15 54.5 1.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase YorP PF09629.5 EMC91990.1 - 0.07 13.1 0.3 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 YorP protein dsrm PF00035.20 EMC91992.1 - 8e-05 23.1 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF4072 PF13284.1 EMC91992.1 - 2.2 8.5 4.1 0.46 10.7 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) TMC PF07810.8 EMC91994.1 - 0.029 14.8 0.0 0.042 14.2 0.0 1.5 1 1 0 1 1 1 0 TMC domain Adeno_E4_34 PF04528.8 EMC91996.1 - 0.067 12.7 0.2 0.088 12.3 0.1 1.1 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region WD40 PF00400.27 EMC91997.1 - 1.6e-07 30.9 5.4 0.2 11.5 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat Lactonase PF10282.4 EMC91997.1 - 0.001 18.2 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.7 EMC91997.1 - 0.052 13.2 0.0 25 4.6 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cpn10 PF00166.16 EMC91998.1 - 6.9e-30 102.8 0.0 7.7e-30 102.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit HET PF06985.6 EMC91999.1 - 6.3e-13 49.0 0.0 6.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_76 PF03663.9 EMC92001.1 - 1.4e-99 333.9 21.0 2.5e-99 333.1 14.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4358 PF14270.1 EMC92002.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) zf-DBF PF07535.7 EMC92002.1 - 0.14 11.8 0.5 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 DBF zinc finger F-box PF00646.28 EMC92003.1 - 8.5e-09 34.8 0.0 3.4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMC92003.1 - 6.2e-08 32.2 0.0 2.5e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 F-box-like Metallophos PF00149.23 EMC92004.1 - 1.1e-43 148.9 0.9 1.4e-43 148.6 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNase_H2_suC PF08615.6 EMC92005.1 - 8.5e-27 93.6 0.0 1e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.15 EMC92006.1 - 2.5e-65 220.2 0.0 1.8e-64 217.5 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EMC92006.1 - 1.6e-10 40.9 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC92006.1 - 4.3e-09 36.9 0.0 8.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC92006.1 - 1.3e-08 35.1 0.0 2.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC92006.1 - 9.8e-08 31.7 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC92006.1 - 1.1e-05 25.8 0.0 2.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC92006.1 - 7e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EMC92006.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF938 PF06080.7 EMC92006.1 - 0.013 15.0 0.0 0.061 12.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Met_10 PF02475.11 EMC92006.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.9 EMC92006.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EMC92006.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EMC92008.1 - 1.5e-13 51.0 0.1 5e-13 49.3 0.0 1.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC92008.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC92008.1 - 1.6e-08 34.9 0.0 2.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC92008.1 - 4e-08 33.8 0.1 1.5e-07 31.9 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC92008.1 - 5.5e-08 32.2 0.0 1.1e-07 31.2 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EMC92008.1 - 2.5e-07 30.4 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC92008.1 - 4.2e-05 23.0 0.1 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMC92008.1 - 7.4e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC92008.1 - 0.00038 20.0 0.1 0.00076 19.0 0.1 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EMC92008.1 - 0.0012 17.9 0.1 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EMC92008.1 - 0.0025 16.8 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EMC92008.1 - 0.0033 17.1 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMC92008.1 - 0.005 15.9 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMC92008.1 - 0.0088 16.0 0.3 0.088 12.8 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC92008.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.7 EMC92008.1 - 0.033 13.5 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.7 EMC92008.1 - 0.047 12.5 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.12 EMC92008.1 - 0.075 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 EMC92008.1 - 0.11 11.7 0.1 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Metallophos PF00149.23 EMC92009.1 - 1.7e-37 128.7 0.6 1.1e-29 103.2 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF2802 PF10975.3 EMC92010.1 - 0.0046 16.6 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2802) DUF3416 PF11896.3 EMC92010.1 - 0.22 11.4 6.7 1.9 8.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3416) ING PF12998.2 EMC92010.1 - 0.26 11.5 2.1 9.8 6.5 0.2 2.4 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding OmpH PF03938.9 EMC92010.1 - 2.2 8.2 6.1 3.1 7.7 3.7 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.1 EMC92010.1 - 3.3 7.6 9.5 37 4.2 6.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) MFS_1 PF07690.11 EMC92011.1 - 1.2e-41 142.6 54.8 1.2e-41 142.6 38.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC92011.1 - 9.2e-13 47.2 26.8 1.2e-12 46.8 18.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC92011.1 - 4.5e-06 25.5 13.5 4.5e-06 25.5 9.4 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter PDR_assoc PF08370.6 EMC92011.1 - 0.12 11.8 3.4 0.33 10.5 0.2 3.3 2 1 1 3 3 3 0 Plant PDR ABC transporter associated Zn_clus PF00172.13 EMC92012.1 - 1e-05 25.3 9.5 2.2e-05 24.2 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC92012.1 - 0.0022 16.9 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 EMC92013.1 - 4.2e-39 134.0 0.0 4.8e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 EMC92013.1 - 0.085 13.0 0.0 0.66 10.1 0.0 2.0 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase NmrA PF05368.8 EMC92014.1 - 1.2e-20 73.7 0.0 1.6e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC92014.1 - 1.4e-10 41.4 0.1 2.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMC92014.1 - 1.6e-05 25.1 0.0 5e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMC92014.1 - 0.0004 19.4 0.1 0.00057 18.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMC92014.1 - 0.00074 19.6 0.1 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EMC92014.1 - 0.0024 17.3 0.0 0.0066 15.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EMC92014.1 - 0.0034 17.2 0.1 0.0076 16.1 0.0 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EMC92014.1 - 0.0087 15.0 0.1 0.017 14.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EMC92014.1 - 0.025 14.2 0.1 0.053 13.1 0.0 1.5 2 0 0 2 2 2 0 KR domain UT PF03253.9 EMC92016.1 - 0.077 11.8 0.5 0.097 11.5 0.3 1.2 1 0 0 1 1 1 0 Urea transporter FA_hydroxylase PF04116.8 EMC92017.1 - 4.7e-20 72.0 12.9 3.2e-19 69.3 6.8 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily UBA_4 PF14555.1 EMC92018.1 - 0.0011 18.4 0.2 0.002 17.6 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 EMC92018.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 LysM domain zf-RING_2 PF13639.1 EMC92018.1 - 0.098 12.5 10.3 0.18 11.6 7.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EMC92018.1 - 0.23 11.2 12.0 0.24 11.1 7.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.2 EMC92018.1 - 2.3 8.1 10.9 5.4 6.9 7.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon Dus PF01207.12 EMC92019.1 - 4.6e-60 203.0 0.0 6.5e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) p450 PF00067.17 EMC92021.1 - 6.9e-28 97.3 0.0 1.6e-19 69.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 NAD_binding_10 PF13460.1 EMC92022.1 - 1.9e-26 93.2 1.0 2.4e-26 92.8 0.7 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC92022.1 - 8.7e-11 41.7 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMC92022.1 - 7.4e-09 35.1 0.4 1.5e-08 34.2 0.3 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EMC92022.1 - 1.8e-05 23.8 0.1 5.9e-05 22.1 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein Glyco_transf_4 PF13439.1 EMC92022.1 - 8.2e-05 22.3 0.0 0.0033 17.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 3Beta_HSD PF01073.14 EMC92022.1 - 0.00011 20.9 0.0 0.00015 20.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_trans_4_4 PF13579.1 EMC92022.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.7 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain RmlD_sub_bind PF04321.12 EMC92022.1 - 0.012 14.5 0.2 0.021 13.7 0.1 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.20 EMC92022.1 - 0.014 15.2 0.5 0.041 13.7 0.4 1.9 1 1 0 1 1 1 0 short chain dehydrogenase Ligase_CoA PF00549.14 EMC92022.1 - 0.023 14.3 0.4 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 CoA-ligase DUF1593 PF07632.6 EMC92022.1 - 0.026 13.8 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) Glyco_transf_5 PF08323.6 EMC92022.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Starch synthase catalytic domain Peptidase_M24 PF00557.19 EMC92023.1 - 1.1e-50 172.0 0.0 1.6e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMC92023.1 - 6.1e-26 90.3 0.0 1.8e-25 88.8 0.0 1.7 1 1 1 2 2 2 1 Aminopeptidase P, N-terminal domain HSP70 PF00012.15 EMC92026.1 - 5.9e-57 192.9 11.0 5e-54 183.2 0.0 2.8 3 1 0 3 3 3 2 Hsp70 protein Interferon PF00143.14 EMC92026.1 - 0.0027 17.5 0.1 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 Interferon alpha/beta domain MreB_Mbl PF06723.8 EMC92026.1 - 0.094 11.2 0.0 0.25 9.9 0.0 1.7 1 0 0 1 1 1 0 MreB/Mbl protein Flavin_Reduct PF01613.13 EMC92027.1 - 9.8e-17 61.2 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_1 PF00561.15 EMC92028.1 - 8.2e-10 38.6 0.0 6e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC92028.1 - 7.5e-06 25.9 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAP_central PF04928.12 EMC92029.1 - 3.7e-96 320.8 0.0 5.3e-96 320.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EMC92029.1 - 9.8e-42 142.1 0.0 1.5e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EMC92029.1 - 5.8e-07 29.7 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain GFA PF04828.9 EMC92030.1 - 1.5e-23 82.5 0.0 2e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EMC92030.1 - 0.029 13.5 0.1 0.029 13.5 0.0 2.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMC92030.1 - 0.033 13.6 0.2 0.033 13.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EMC92030.1 - 0.083 12.5 2.9 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DZR PF12773.2 EMC92030.1 - 0.15 11.9 4.6 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 EMC92030.1 - 0.45 10.2 0.1 0.45 10.2 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.6 EMC92030.1 - 0.69 9.6 0.1 0.69 9.6 0.1 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.7 EMC92030.1 - 4.2 7.5 7.8 13 6.0 2.6 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Tbf5 PF06331.7 EMC92031.1 - 6.6e-19 67.4 3.1 7.4e-19 67.2 2.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 adh_short PF00106.20 EMC92032.1 - 7.6e-21 74.7 1.4 1.1e-20 74.1 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92032.1 - 1e-20 74.5 0.0 1.4e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92032.1 - 3.9e-08 33.1 0.3 5.9e-08 32.5 0.2 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 EMC92033.1 - 1.2e-26 93.2 48.8 1.3e-25 89.8 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4191 PF13829.1 EMC92033.1 - 4 6.4 4.5 22 4.0 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4202 PF13875.1 EMC92034.1 - 7.8e-74 247.3 1.2 8.7e-74 247.1 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF2102 PF09875.4 EMC92034.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Glyco_hydro_2 PF00703.16 EMC92035.1 - 1.2e-09 38.5 0.0 3.4e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EMC92035.1 - 5e-09 35.9 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMC92035.1 - 0.061 12.2 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Arf PF00025.16 EMC92038.1 - 1.1e-40 138.7 0.0 3.3e-26 91.5 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EMC92038.1 - 1.4e-13 50.3 0.0 6.1e-07 28.4 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMC92038.1 - 3.8e-09 36.1 0.0 2.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 EMC92038.1 - 3.1e-08 33.0 0.0 3.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC92038.1 - 4.5e-07 30.3 0.0 1.4e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EMC92038.1 - 3.5e-06 26.3 0.0 9.2e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMC92038.1 - 4.9e-06 26.0 0.0 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC92038.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC92038.1 - 0.024 13.9 0.0 0.067 12.4 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EMC92038.1 - 0.046 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_S25 PF03297.10 EMC92039.1 - 2.3e-37 127.2 3.7 2.6e-37 127.0 2.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 EMC92039.1 - 0.0042 16.7 0.1 0.0055 16.3 0.1 1.2 1 0 0 1 1 1 1 MarR family FeoC PF09012.5 EMC92039.1 - 0.0069 16.0 0.4 0.02 14.5 0.0 1.8 1 1 1 2 2 2 1 FeoC like transcriptional regulator HTH_DeoR PF08220.7 EMC92039.1 - 0.013 14.9 0.2 0.019 14.5 0.2 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.7 EMC92039.1 - 0.041 13.5 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 HTH domain Stk19 PF10494.4 EMC92039.1 - 0.058 12.7 0.1 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 HTH_24 PF13412.1 EMC92039.1 - 0.072 12.4 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GntR PF00392.16 EMC92039.1 - 0.15 11.5 0.2 0.23 10.9 0.1 1.4 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family Aldo_ket_red PF00248.16 EMC92040.1 - 4.2e-30 104.5 0.0 1.8e-29 102.4 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Nol1_Nop2_Fmu PF01189.12 EMC92041.1 - 3.5e-18 65.9 0.1 4.1e-11 42.8 0.0 3.0 3 0 0 3 3 3 2 NOL1/NOP2/sun family Abhydrolase_6 PF12697.2 EMC92042.1 - 2.3e-36 125.8 0.2 2.7e-36 125.5 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC92042.1 - 1.1e-21 77.1 0.0 2.7e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC92042.1 - 1.6e-13 50.7 0.0 9.7e-12 44.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMC92042.1 - 1.7e-09 37.4 0.0 3.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PAF-AH_p_II PF03403.8 EMC92042.1 - 2.1e-06 26.2 0.0 4.2e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_4 PF08386.5 EMC92042.1 - 0.00017 21.3 0.0 0.00064 19.5 0.0 1.8 1 1 1 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.16 EMC92042.1 - 0.00054 19.2 0.0 0.0099 15.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EMC92042.1 - 0.00091 18.7 0.3 0.0062 15.9 0.2 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.9 EMC92042.1 - 0.013 14.0 0.0 0.41 9.0 0.0 2.1 2 0 0 2 2 2 0 Ndr family DLH PF01738.13 EMC92042.1 - 0.026 13.8 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF3487 PF11990.3 EMC92042.1 - 0.064 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) NdhN PF11909.3 EMC92042.1 - 0.092 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Esterase PF00756.15 EMC92042.1 - 0.12 11.7 0.4 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 EMC92042.1 - 0.12 10.8 0.1 0.26 9.7 0.0 1.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_hydro_16 PF00722.16 EMC92043.1 - 4.9e-12 45.5 1.3 8e-12 44.8 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RskA PF10099.4 EMC92043.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA NDUF_B4 PF07225.7 EMC92044.1 - 5.4e-05 22.9 0.1 6.1e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) MscS_TM PF12794.2 EMC92044.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 IPI_T4 PF11634.3 EMC92045.1 - 0.14 12.0 0.1 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 GMC_oxred_N PF00732.14 EMC92046.1 - 2.3e-42 145.1 0.1 2.1e-41 142.0 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC92046.1 - 6.5e-29 101.0 0.9 1.8e-28 99.6 0.0 2.1 3 0 0 3 3 3 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMC92046.1 - 1e-08 34.4 1.1 1.9e-07 30.3 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EMC92046.1 - 2.7e-08 33.1 9.6 2.3e-07 30.0 6.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC92046.1 - 3.6e-07 30.2 0.1 2.4e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC92046.1 - 3.3e-06 26.3 0.1 6.6e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMC92046.1 - 1.7e-05 24.7 0.3 7.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMC92046.1 - 6.6e-05 22.1 0.5 0.00018 20.7 0.4 1.7 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EMC92046.1 - 0.0035 15.8 1.6 0.0038 15.7 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EMC92046.1 - 0.0042 16.2 2.3 0.0071 15.4 1.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMC92046.1 - 0.0067 15.3 0.1 0.029 13.2 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A ThiF PF00899.16 EMC92046.1 - 0.047 13.4 0.1 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 EMC92046.1 - 0.054 13.1 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EMC92046.1 - 0.058 12.3 0.1 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMC92046.1 - 0.088 13.2 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMC92046.1 - 0.097 12.9 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EMC92046.1 - 0.48 9.7 1.7 0.91 8.8 1.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FYVE PF01363.16 EMC92047.1 - 9.2e-15 54.2 11.9 1.5e-14 53.5 8.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger DNA_pol_viral_C PF00336.13 EMC92047.1 - 0.0094 15.2 1.2 0.015 14.5 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain DUF2678 PF10856.3 EMC92048.1 - 1.1 8.9 7.1 0.068 12.9 0.9 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) MIF PF01187.13 EMC92049.1 - 4.3e-14 52.5 0.0 5.7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Sec63 PF02889.11 EMC92051.1 - 1.6e-40 139.2 0.0 2.5e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EMC92051.1 - 6.3e-16 57.8 0.1 1.4e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 EMC92052.1 - 7.2e-25 87.6 0.0 1.2e-24 86.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Mg_trans_NIPA PF05653.9 EMC92053.1 - 4e-106 354.3 12.7 5.1e-106 354.0 8.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMC92053.1 - 3.4e-06 27.2 5.3 3.4e-06 27.2 3.7 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC92053.1 - 0.00027 20.9 7.0 0.00027 20.9 4.9 3.2 2 2 0 2 2 2 1 EamA-like transporter family DUF2937 PF11157.3 EMC92053.1 - 0.99 8.7 4.1 0.45 9.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Cation_ATPase_C PF00689.16 EMC92053.1 - 4.6 6.7 17.0 0.35 10.3 6.9 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus FAD_binding_3 PF01494.14 EMC92057.1 - 2e-16 60.0 1.7 3.5e-11 42.7 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EMC92057.1 - 6.4e-08 32.7 0.5 3.6e-07 30.2 0.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC92057.1 - 1.1e-07 31.0 0.8 0.00032 19.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC92057.1 - 3.1e-06 26.2 0.5 6e-06 25.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMC92057.1 - 2.6e-05 22.8 0.5 0.0025 16.3 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EMC92057.1 - 0.00015 20.9 1.2 0.00015 20.9 0.8 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC92057.1 - 0.00016 21.8 0.2 0.00045 20.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC92057.1 - 0.0006 19.7 0.3 0.0016 18.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EMC92057.1 - 0.00096 18.1 0.1 0.0015 17.4 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EMC92057.1 - 0.001 19.4 1.7 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMC92057.1 - 0.01 15.4 0.3 0.037 13.5 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EMC92057.1 - 0.031 13.3 0.1 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EMC92057.1 - 0.053 12.4 1.1 0.11 11.3 0.1 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EMC92057.1 - 0.43 9.1 3.5 0.9 8.0 0.4 2.1 1 1 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.11 EMC92058.1 - 1.6e-29 102.7 26.3 1.6e-29 102.7 18.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sars6 PF12133.3 EMC92058.1 - 0.077 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Ribosomal_S7 PF00177.16 EMC92060.1 - 1.8e-39 134.6 1.4 2.1e-39 134.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Abhydrolase_6 PF12697.2 EMC92061.1 - 7e-06 26.0 2.7 4.8e-05 23.3 0.3 2.9 2 2 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 EMC92061.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EMC92061.1 - 0.029 13.6 0.1 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EMC92061.1 - 0.033 13.7 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_3 PF00933.16 EMC92062.1 - 6.6e-52 176.3 0.0 8.9e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMC92062.1 - 8.4e-07 28.7 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain BTB_2 PF02214.17 EMC92064.1 - 2.2e-06 27.7 0.1 0.0053 16.9 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EMC92064.1 - 0.17 11.8 0.0 28 4.7 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain GST_N PF02798.15 EMC92066.1 - 2.1e-06 27.7 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMC92066.1 - 2.9e-06 27.3 0.0 4.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC92066.1 - 5.5e-05 23.0 0.0 0.00025 20.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC92066.1 - 0.0031 17.3 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC92066.1 - 0.0061 17.0 0.0 0.011 16.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC92066.1 - 0.0088 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PIGA PF08288.7 EMC92067.1 - 1.7e-42 143.6 0.7 1.7e-42 143.6 0.5 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EMC92067.1 - 2.1e-25 89.1 0.0 3.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMC92067.1 - 2.3e-14 53.5 1.1 4e-14 52.7 0.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EMC92067.1 - 3.2e-13 49.9 0.0 6.8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMC92067.1 - 2.2e-12 47.3 0.1 4.4e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EMC92067.1 - 0.0014 18.8 0.0 0.0041 17.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EMC92067.1 - 0.0046 16.7 0.2 0.0081 16.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like DEAD PF00270.24 EMC92068.1 - 9.1e-28 96.8 0.1 8.1e-13 48.2 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC92068.1 - 4.7e-11 42.4 0.1 1.1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC92068.1 - 1.5e-05 24.8 0.0 5.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Choline_sulf_C PF12411.3 EMC92070.1 - 0.023 14.5 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal DUF515 PF04415.7 EMC92071.1 - 0.035 12.3 8.1 0.04 12.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RAP1 PF07218.6 EMC92071.1 - 1.1 7.2 6.5 1.2 7.1 4.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IKI3 PF04762.7 EMC92073.1 - 0.00053 17.9 0.0 0.091 10.5 0.0 2.8 3 0 0 3 3 3 2 IKI3 family PD40 PF07676.7 EMC92073.1 - 0.0033 17.0 0.5 0.51 10.0 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EMC92073.1 - 0.0086 15.8 0.0 0.74 9.4 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A eIF-1a PF01176.14 EMC92073.1 - 0.18 11.2 0.0 3 7.3 0.0 2.6 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 WD40 PF00400.27 EMC92073.1 - 0.2 11.6 3.7 14 5.7 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat BP28CT PF08146.7 EMC92075.1 - 2.2e-36 124.9 4.4 1.7e-35 122.0 0.1 3.8 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EMC92075.1 - 6.1e-21 74.6 1.4 6.1e-21 74.6 0.9 5.0 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EMC92075.1 - 3.3e-07 29.8 1.2 0.72 10.0 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EMC92075.1 - 0.32 11.5 17.9 0.64 10.5 0.0 7.9 8 1 2 10 10 10 0 HEAT-like repeat NRDE-2 PF08424.5 EMC92076.1 - 4.3e-73 246.0 0.0 5.6e-72 242.3 0.0 2.5 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 EMC92076.1 - 0.00087 18.8 0.6 0.0034 16.9 0.4 2.0 1 0 0 1 1 1 1 TPR repeat TPR_9 PF13371.1 EMC92076.1 - 0.0024 17.6 0.1 0.011 15.5 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3906 PF13046.1 EMC92076.1 - 0.016 14.8 0.0 0.057 13.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) TPR_19 PF14559.1 EMC92076.1 - 0.025 14.8 2.0 0.46 10.8 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC92076.1 - 0.075 13.7 0.0 0.075 13.7 0.0 7.5 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMC92076.1 - 0.25 12.0 11.0 1.8 9.3 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat ELO PF01151.13 EMC92077.1 - 1.4e-76 257.1 6.2 1.7e-76 256.8 4.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family adh_short PF00106.20 EMC92078.1 - 2.1e-19 70.0 1.2 4.9e-19 68.8 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMC92078.1 - 2.4e-08 33.8 0.1 3.6e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC92078.1 - 7.6e-05 22.5 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC92078.1 - 0.00029 20.3 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EMC92078.1 - 0.0041 17.2 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EMC92081.1 - 3.2e-27 95.3 0.0 4.5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMC92081.1 - 4.2e-27 94.6 0.1 6.7e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMC92081.1 - 0.0044 17.4 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EMC92081.1 - 0.016 15.2 0.0 0.05 13.6 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 EMC92081.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMC92081.1 - 0.04 13.2 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMC92081.1 - 0.046 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus EF-hand_1 PF00036.27 EMC92082.1 - 3.1e-26 88.6 12.5 6.2e-07 28.2 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC92082.1 - 5e-23 81.0 3.4 1.6e-12 47.3 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC92082.1 - 2.6e-20 70.4 5.1 4.2e-05 23.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC92082.1 - 3.7e-18 63.9 11.9 5.3e-06 25.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EMC92082.1 - 1.2e-15 56.8 12.8 1.1e-05 24.9 0.6 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC92082.1 - 7e-07 29.2 0.0 0.0007 19.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC92082.1 - 5.1e-06 26.1 7.9 0.0023 17.6 0.3 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC92082.1 - 0.025 14.4 0.1 1.1 9.1 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain DUF1770 PF08589.5 EMC92083.1 - 3.8e-24 85.1 0.4 5.9e-24 84.5 0.3 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Sulfotransfer_3 PF13469.1 EMC92085.1 - 0.00063 20.7 0.0 0.003 18.4 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family DUF936 PF06075.7 EMC92086.1 - 9.9 4.9 34.3 13 4.5 23.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SAP18 PF06487.7 EMC92087.1 - 3.3e-27 94.6 0.0 4.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 EMC92088.1 - 2.7e-49 166.7 0.0 2.7e-49 166.7 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EMC92088.1 - 6.2e-10 38.1 1.0 6.2e-10 38.1 0.7 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like DUF2413 PF10310.4 EMC92088.1 - 0.92 8.2 12.6 1.4 7.6 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PLDc_2 PF13091.1 EMC92090.1 - 3.4e-19 68.8 0.0 2.7e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMC92090.1 - 0.052 13.3 0.0 7.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif Na_H_Exchanger PF00999.16 EMC92091.1 - 9.4e-56 188.9 15.5 1.1e-55 188.7 10.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.15 EMC92091.1 - 0.36 10.0 3.6 0.37 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF21 zf-U1 PF06220.7 EMC92095.1 - 2.3e-23 81.4 4.7 3e-23 81.0 3.3 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EMC92095.1 - 0.0072 16.4 5.5 0.03 14.4 3.8 1.9 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 EMC92095.1 - 0.024 14.4 0.1 0.024 14.4 0.1 1.0 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Fungal_trans PF04082.13 EMC92099.1 - 1.1e-13 50.6 2.5 2.2e-13 49.6 0.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EMC92099.1 - 1.1e-05 25.3 9.1 0.005 17.0 1.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC92099.1 - 0.0002 21.5 15.0 0.015 15.6 1.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FG-GAP PF01839.18 EMC92099.1 - 0.28 10.9 1.0 5.9 6.7 0.3 2.6 2 0 0 2 2 2 0 FG-GAP repeat zf-C2H2_jaz PF12171.3 EMC92099.1 - 0.69 10.1 3.7 0.78 9.9 1.2 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC92099.1 - 2.7 8.0 5.1 19 5.3 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC92099.1 - 9.1 6.7 10.0 2.5 8.5 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double domain GTP_EFTU PF00009.22 EMC92100.1 - 2.6e-48 163.9 0.0 4.1e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EMC92100.1 - 1.4e-36 124.6 3.8 2.5e-36 123.8 2.7 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EMC92100.1 - 4e-19 68.2 0.0 9e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMC92100.1 - 4.1e-07 30.0 0.0 8.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC92100.1 - 2.4e-05 24.2 0.0 8e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EMC92100.1 - 5.3e-05 22.6 0.0 0.00022 20.6 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.1 EMC92100.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EMC92100.1 - 0.013 14.6 0.0 0.028 13.6 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC92100.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein HORMA PF02301.13 EMC92101.1 - 6.5e-46 156.4 0.5 7.5e-46 156.2 0.3 1.0 1 0 0 1 1 1 1 HORMA domain AhpC-TSA_2 PF13911.1 EMC92101.1 - 0.0063 16.4 0.0 0.013 15.3 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF3349 PF11829.3 EMC92101.1 - 0.073 13.5 0.1 2.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Stirrup PF09061.1 EMC92101.1 - 0.079 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Stirrup RICH PF05062.7 EMC92101.1 - 0.22 11.6 3.1 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 RICH domain Glyco_trans_2_3 PF13632.1 EMC92102.1 - 4.8e-46 156.9 1.2 4.8e-46 156.9 0.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC92102.1 - 7.6e-09 35.7 0.2 1.2e-07 31.7 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC92102.1 - 9.3e-07 28.6 0.0 0.00013 21.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMC92102.1 - 0.0066 15.7 0.1 0.03 13.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Amidohydro_4 PF13147.1 EMC92103.1 - 5.3e-09 36.5 0.1 6.7e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EMC92103.1 - 1.1e-07 31.7 0.7 1.5e-06 27.9 0.2 2.0 1 1 1 2 2 2 2 Amidohydrolase GFA PF04828.9 EMC92105.1 - 9.2e-23 80.0 0.6 1.4e-22 79.4 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EMC92105.1 - 0.0058 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-PHD-like PF15446.1 EMC92106.1 - 6.3e-67 224.2 14.5 1.7e-66 222.7 10.0 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EMC92106.1 - 2.6e-56 190.5 0.0 3.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC92106.1 - 9.7e-13 47.7 0.0 2.5e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMC92106.1 - 4.7e-08 32.2 0.0 1.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EMC92106.1 - 2.4e-05 23.9 2.2 0.11 12.1 0.0 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EMC92106.1 - 0.00051 19.6 8.4 0.00051 19.6 5.8 3.2 2 1 0 2 2 2 1 PHD-finger DUF1087 PF06465.8 EMC92106.1 - 0.029 14.2 0.3 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Diphthamide_syn PF01866.12 EMC92106.1 - 0.037 13.2 0.1 0.075 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative diphthamide synthesis protein ResIII PF04851.10 EMC92106.1 - 0.041 13.7 0.0 0.19 11.5 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PHD_2 PF13831.1 EMC92106.1 - 0.34 10.2 15.5 0.072 12.4 5.4 3.3 2 1 0 2 2 2 0 PHD-finger SnAC PF14619.1 EMC92106.1 - 1.1 9.4 10.9 0.15 12.2 0.2 3.5 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex SpoU_methylase PF00588.14 EMC92107.1 - 4.6e-25 88.1 0.0 8.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EMC92107.1 - 3.9e-09 36.5 0.0 6.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding HTH_39 PF14090.1 EMC92107.1 - 0.02 14.3 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain GST_N_3 PF13417.1 EMC92108.1 - 1.5e-09 37.9 0.1 2.8e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC92108.1 - 1.8e-06 27.8 0.0 3.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC92108.1 - 0.00029 21.2 0.0 0.00057 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC92108.1 - 0.00071 19.4 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC92108.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC92108.1 - 0.061 13.5 0.0 0.2 11.8 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Prok-E2_A PF14457.1 EMC92109.1 - 0.083 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family A LMWPc PF01451.16 EMC92110.1 - 6.9e-29 100.9 0.0 8.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MFS_1 PF07690.11 EMC92111.1 - 9.9e-44 149.4 22.4 3.9e-41 140.9 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC92111.1 - 5.2e-14 51.6 3.9 5.2e-14 51.6 2.7 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMC92111.1 - 7.7e-09 34.2 6.1 7.7e-09 34.2 4.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.6 EMC92111.1 - 2.7 7.2 6.2 17 4.6 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) ICL PF00463.16 EMC92112.1 - 5.5e-280 929.0 0.9 6.3e-280 928.8 0.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EMC92112.1 - 1.7e-11 43.8 0.1 5.7e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.11 EMC92113.1 - 3.4e-42 144.4 46.9 4e-38 131.0 16.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC92113.1 - 1.5e-16 60.0 7.6 1.5e-16 60.0 5.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EMC92113.1 - 0.00098 17.2 10.8 0.09 10.8 0.1 3.9 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family DUF2500 PF10694.4 EMC92113.1 - 0.016 15.2 0.2 0.17 11.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) TPMT PF05724.6 EMC92114.1 - 5.4e-35 120.8 0.0 2.1e-33 115.6 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 EMC92114.1 - 1.8e-08 34.2 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC92114.1 - 8e-08 32.6 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC92114.1 - 3.3e-07 29.9 0.0 5e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC92114.1 - 5.6e-07 29.9 0.0 1.4e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC92114.1 - 6.9e-06 26.6 0.0 1.3e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC92114.1 - 3.7e-05 23.7 0.0 7.7e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC92114.1 - 9.9e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EMC92114.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TehB PF03848.9 EMC92114.1 - 0.0079 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF1446 PF07287.6 EMC92116.1 - 1.8e-131 437.8 0.3 2.2e-131 437.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) FAD_binding_4 PF01565.18 EMC92116.1 - 0.036 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HSP70 PF00012.15 EMC92117.1 - 3.3e-11 41.8 0.7 1.8e-09 36.0 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EMC92117.1 - 0.0026 17.3 0.1 0.0075 15.8 0.1 1.7 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EMC92117.1 - 0.014 14.0 0.1 0.11 11.1 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Nucleoplasmin PF03066.10 EMC92118.1 - 0.0014 18.1 0.4 0.0029 17.1 0.2 1.5 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 EMC92118.1 - 5.2 7.3 9.1 13 6.1 6.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PEX11 PF05648.9 EMC92119.1 - 7.4e-15 54.8 0.2 3.3e-14 52.6 0.1 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NmrA PF05368.8 EMC92120.1 - 2.9e-14 52.8 0.0 1.5e-11 43.9 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EMC92120.1 - 1.6e-05 24.9 0.1 4.1e-05 23.6 0.1 1.7 1 1 0 2 2 2 1 NADH(P)-binding Voltage_CLC PF00654.15 EMC92121.1 - 0.081 11.9 3.5 0.18 10.8 0.0 2.4 2 1 0 2 2 2 0 Voltage gated chloride channel bZIP_1 PF00170.16 EMC92123.1 - 2.4e-08 33.7 6.2 2.4e-08 33.7 4.3 2.4 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EMC92123.1 - 1e-05 25.2 5.6 1e-05 25.2 3.8 2.7 3 0 0 3 3 3 1 Basic region leucine zipper Macoilin PF09726.4 EMC92123.1 - 0.0011 17.4 13.2 0.0018 16.6 9.1 1.3 1 0 0 1 1 1 1 Transmembrane protein bZIP_Maf PF03131.12 EMC92123.1 - 0.0028 17.8 7.5 0.0028 17.8 5.2 3.1 2 1 1 3 3 3 1 bZIP Maf transcription factor DUF1390 PF07150.6 EMC92123.1 - 0.12 11.7 1.9 0.18 11.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) MRP-S31 PF15433.1 EMC92123.1 - 0.19 11.1 14.2 0.3 10.4 9.8 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pilin PF00114.14 EMC92125.1 - 1.1 10.0 7.9 0.44 11.2 2.2 2.1 2 0 0 2 2 2 0 Pilin (bacterial filament) BCAS2 PF05700.6 EMC92127.1 - 1.3e-34 119.6 0.0 1.5e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4510 PF14971.1 EMC92127.1 - 0.33 11.0 5.1 0.43 10.7 2.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) RNA_pol_Rpb1_5 PF04998.12 EMC92129.1 - 1.3e-85 287.0 0.0 2.5e-85 286.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EMC92129.1 - 4.2e-84 282.6 0.0 6.1e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EMC92129.1 - 7e-66 221.2 0.1 1.3e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EMC92129.1 - 2.4e-35 121.5 0.0 6e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EMC92129.1 - 3.7e-29 100.6 0.1 8.8e-29 99.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FHA PF00498.21 EMC92130.1 - 1e-14 54.3 0.0 2.2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain FYVE PF01363.16 EMC92131.1 - 0.0033 17.2 2.7 0.0033 17.2 1.9 2.6 3 0 0 3 3 3 1 FYVE zinc finger F-box-like PF12937.2 EMC92131.1 - 0.16 11.6 0.2 0.16 11.6 0.1 2.0 3 0 0 3 3 3 0 F-box-like zf-C3HC4_2 PF13923.1 EMC92131.1 - 5.8 7.0 12.4 12 6.0 3.5 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 EMC92131.1 - 6.8 6.6 8.5 0.48 10.3 0.7 2.5 2 0 0 2 2 2 0 B-box zinc finger Pkinase PF00069.20 EMC92132.1 - 1.1e-23 83.7 0.0 1.3e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92132.1 - 7.8e-15 54.6 0.0 9.3e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC92132.1 - 0.021 13.7 0.1 3.7 6.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Oxysterol_BP PF01237.13 EMC92133.1 - 5e-112 373.9 0.0 1.2e-111 372.6 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EMC92133.1 - 8.7e-36 121.8 0.1 8.7e-36 121.8 0.1 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EMC92133.1 - 0.00046 20.3 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC92133.1 - 0.025 14.8 1.7 1.4 9.2 1.2 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain DUF3602 PF12223.3 EMC92134.1 - 1.7e-10 41.1 9.4 1.5e-06 28.4 0.2 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Actin PF00022.14 EMC92135.1 - 1.5e-130 435.1 0.0 1.7e-130 434.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMC92135.1 - 0.0048 15.5 0.0 2.4 6.6 0.0 2.8 2 1 0 2 2 2 2 MreB/Mbl protein zf-C2H2_4 PF13894.1 EMC92136.1 - 0.00027 21.0 1.4 0.16 12.3 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC92136.1 - 0.065 13.4 0.3 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EMC92136.1 - 0.076 13.3 4.2 0.77 10.2 0.1 2.7 2 1 0 2 2 2 0 Zinc finger, C2H2 type Proteasome PF00227.21 EMC92138.1 - 5.5e-49 166.0 0.1 7.8e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC92138.1 - 4.8e-12 44.9 0.2 7.8e-12 44.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 EMC92138.1 - 0.58 9.6 2.2 0.56 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 EMC92139.1 - 1.2e-22 79.2 0.3 1.9e-22 78.5 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Amidase PF01425.16 EMC92140.1 - 4.1e-33 114.8 2.2 4.8e-33 114.6 0.9 1.4 2 0 0 2 2 2 1 Amidase TauE PF01925.14 EMC92141.1 - 0.083 12.3 3.0 0.14 11.5 2.1 1.4 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Aft1_HRA PF11786.3 EMC92143.1 - 2.3e-28 98.2 10.8 2.3e-28 98.2 7.5 2.8 2 1 1 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 EMC92143.1 - 7e-15 55.8 10.4 7e-15 55.8 7.2 3.6 3 1 2 5 5 5 1 Aft1 HRR domain bZIP_1 PF00170.16 EMC92143.1 - 7.4e-14 51.4 3.4 1.3e-13 50.6 2.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC92143.1 - 8.6e-07 28.6 5.7 1.5e-06 27.8 4.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 EMC92143.1 - 1.2e-06 28.9 7.9 1.2e-06 28.9 5.5 4.1 5 1 0 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.12 EMC92143.1 - 0.0017 18.6 1.8 0.004 17.4 1.3 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.9 EMC92143.1 - 0.035 14.0 0.9 0.068 13.1 0.6 1.5 1 0 0 1 1 1 0 Nnf1 ALMS_motif PF15309.1 EMC92143.1 - 0.36 10.6 5.2 0.75 9.6 3.6 1.5 1 0 0 1 1 1 0 ALMS motif TFIIA PF03153.8 EMC92143.1 - 0.47 10.3 20.6 0.67 9.7 14.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spc97_Spc98 PF04130.8 EMC92145.1 - 8.8e-121 403.8 0.0 1.2e-120 403.3 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Chitin_synth_1 PF01644.12 EMC92146.1 - 3.6e-80 267.5 1.0 5.1e-80 267.0 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMC92146.1 - 4.6e-31 106.3 0.1 8.3e-31 105.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMC92146.1 - 5e-23 81.2 5.5 4.1e-19 68.3 0.0 3.0 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMC92146.1 - 3.6e-09 36.6 5.4 3.6e-09 36.6 3.7 2.5 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC92146.1 - 1e-08 35.2 0.0 5.4e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF4522 PF15022.1 EMC92147.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) Myco_arth_vir_N PF09610.5 EMC92147.1 - 1.3 9.0 6.7 3.7 7.5 4.6 1.8 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Chorion_3 PF05387.6 EMC92148.1 - 0.19 11.1 2.6 0.19 11.1 1.8 1.1 1 0 0 1 1 1 0 Chorion family 3 UQ_con PF00179.21 EMC92149.1 - 3.2e-37 127.0 0.0 4.3e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC92149.1 - 0.0047 16.6 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B MOSC PF03473.12 EMC92150.1 - 2.7e-18 65.7 0.0 6.1e-18 64.5 0.0 1.6 1 1 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EMC92150.1 - 1e-15 57.5 0.0 1.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain GFA PF04828.9 EMC92151.1 - 0.00077 19.3 2.8 0.00077 19.3 2.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme fn3 PF00041.16 EMC92151.1 - 0.031 14.3 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain L_HGMIC_fpl PF10242.4 EMC92152.1 - 4.3e-05 23.5 5.3 7.8e-05 22.7 3.7 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 EMC92152.1 - 5.3e-05 22.9 3.8 5.3e-05 22.9 2.6 1.4 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction AtpR PF12966.2 EMC92152.1 - 0.2 11.8 3.9 6.1 7.0 1.7 2.5 2 0 0 2 2 2 0 N-ATPase, AtpR subunit DUF998 PF06197.8 EMC92152.1 - 0.4 9.9 14.0 2.3 7.5 5.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Pox_A14 PF05767.7 EMC92152.1 - 6.3 6.8 6.5 2.3 8.2 0.6 2.6 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Ceramidase_alk PF04734.8 EMC92154.1 - 1.6e-250 832.6 0.0 1.8e-250 832.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Autotrns_rpt PF12951.2 EMC92154.1 - 1 9.0 3.3 17 5.1 0.1 3.3 3 0 0 3 3 3 0 Autotransporter-associated beta strand repeat Peptidase_S10 PF00450.17 EMC92156.1 - 4.3e-83 279.7 0.0 5.5e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMC92156.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family MRP-L20 PF12824.2 EMC92157.1 - 7e-54 182.2 9.4 9e-54 181.8 6.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EMC92157.1 - 0.00011 22.1 0.6 0.00023 21.0 0.3 1.6 1 1 0 1 1 1 1 Neugrin MRJP PF03022.11 EMC92158.1 - 9.4e-06 25.0 0.0 0.00017 20.9 0.0 2.4 1 1 1 2 2 2 1 Major royal jelly protein SGL PF08450.7 EMC92158.1 - 0.01 15.2 1.1 1.9 7.7 0.0 3.3 2 2 1 4 4 4 0 SMP-30/Gluconolaconase/LRE-like region Con-6 PF10346.4 EMC92159.1 - 3.4e-25 87.1 6.5 2.9e-12 45.7 1.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 NUMOD3 PF07460.6 EMC92159.1 - 0.0099 15.7 2.3 0.37 10.7 0.1 2.8 2 1 1 3 3 3 2 NUMOD3 motif (2 copies) Ketoacyl-synt_C PF02801.17 EMC92160.1 - 0.063 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Cyt-b5 PF00173.23 EMC92161.1 - 1.5e-19 69.5 0.4 8.4e-19 67.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EMC92161.1 - 3.9e-08 33.6 22.0 3.9e-08 33.6 15.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EMC92161.1 - 0.032 14.2 0.2 0.086 12.8 0.1 1.7 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region ATP_synt_I PF03899.10 EMC92161.1 - 0.094 12.8 1.1 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 ATP synthase I chain COX14 PF14880.1 EMC92161.1 - 0.74 9.4 3.5 2 8.0 0.3 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Tubulin_3 PF14881.1 EMC92164.1 - 2.9e-76 254.9 0.0 4.3e-76 254.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EMC92164.1 - 2.1e-40 137.3 0.0 7.1e-40 135.6 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EMC92164.1 - 6.6e-06 26.0 0.0 0.042 13.6 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Mucin PF01456.12 EMC92166.1 - 0.059 13.1 27.1 0.093 12.5 18.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Late_protein_L2 PF00513.13 EMC92166.1 - 2.9 6.6 21.5 3.2 6.4 14.9 1.1 1 0 0 1 1 1 0 Late Protein L2 Cyt-b5 PF00173.23 EMC92170.1 - 3.9e-09 36.1 0.0 5.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Thaumatin PF00314.12 EMC92171.1 - 1.8e-69 233.4 10.0 2.2e-69 233.1 6.9 1.1 1 0 0 1 1 1 1 Thaumatin family Polyketide_cyc2 PF10604.4 EMC92172.1 - 6.6e-07 29.5 0.3 8.1e-07 29.2 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Amidase_6 PF12671.2 EMC92172.1 - 0.07 13.1 0.6 0.094 12.7 0.4 1.2 1 0 0 1 1 1 0 Putative amidase domain SRP-alpha_N PF04086.8 EMC92173.1 - 0.43 9.9 2.2 0.49 9.7 1.6 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3827 PF12877.2 EMC92173.1 - 1.4 6.8 6.9 1.7 6.6 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TruD PF01142.13 EMC92174.1 - 6.6e-54 183.0 0.0 5e-51 173.5 0.0 2.9 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DotA PF11388.3 EMC92174.1 - 0.12 12.4 0.2 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Phagosome trafficking protein DotA Peptidase_S10 PF00450.17 EMC92175.1 - 5.8e-129 430.8 0.1 8.5e-129 430.3 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EMC92175.1 - 1.7e-10 41.0 0.8 2.8e-10 40.3 0.6 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EMC92175.1 - 0.0008 19.3 0.0 0.005 16.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cation_efflux PF01545.16 EMC92176.1 - 5.6e-29 101.1 6.5 6.7e-29 100.8 4.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2235 PF09994.4 EMC92178.1 - 1.2e-65 221.7 0.0 1.6e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) p450 PF00067.17 EMC92179.1 - 1.4e-76 257.9 0.0 1.8e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BDHCT PF08072.6 EMC92180.1 - 0.21 11.7 0.0 0.64 10.1 0.0 1.8 1 0 0 1 1 1 0 BDHCT (NUC031) domain Adap_comp_sub PF00928.16 EMC92181.1 - 1e-18 67.3 0.0 1.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMC92181.1 - 5.8e-08 32.5 0.1 1e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2420 PF10336.4 EMC92182.1 - 5.2e-11 42.1 0.6 1.2e-10 40.9 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) DUF1021 PF06257.6 EMC92183.1 - 0.096 12.3 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1021) Apc4 PF12896.2 EMC92184.1 - 1.1e-37 129.3 0.1 1.7e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EMC92184.1 - 0.00086 18.7 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain VPR PF00522.13 EMC92184.1 - 0.058 13.2 0.3 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 VPR/VPX protein GAT PF03127.9 EMC92185.1 - 2.8e-11 43.2 0.1 1e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EMC92185.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 VHS domain FAD_binding_3 PF01494.14 EMC92186.1 - 7.3e-89 298.2 0.0 9.6e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMC92186.1 - 1.3e-50 171.3 0.0 2.3e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EMC92186.1 - 0.00054 18.9 0.1 0.00093 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMC92186.1 - 0.00061 18.3 0.2 0.001 17.6 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMC92186.1 - 0.0016 18.3 1.4 0.0041 17.0 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC92186.1 - 0.0016 17.5 0.1 0.0042 16.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EMC92186.1 - 0.0031 16.5 0.1 0.013 14.4 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EMC92186.1 - 0.057 12.3 0.2 0.13 11.1 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC92186.1 - 0.09 13.2 0.1 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC92186.1 - 0.11 12.5 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMC92186.1 - 0.11 12.4 0.8 0.38 10.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gtr1_RagA PF04670.7 EMC92187.1 - 6.4e-56 189.0 0.0 8.2e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC92187.1 - 0.0011 17.7 0.7 0.0021 16.8 0.1 1.7 2 0 0 2 2 2 1 G-protein alpha subunit SDA1 PF05285.7 EMC92188.1 - 2.9e-82 276.5 34.1 8.9e-82 274.9 18.2 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EMC92188.1 - 6.4e-21 74.3 0.2 1.8e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Mito_carr PF00153.22 EMC92188.1 - 0.058 13.1 0.1 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial carrier protein Prefoldin_2 PF01920.15 EMC92189.1 - 5.8e-21 74.2 2.1 7.8e-21 73.8 1.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Snapin_Pallidin PF14712.1 EMC92189.1 - 0.012 15.8 3.5 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Seryl_tRNA_N PF02403.17 EMC92189.1 - 0.013 15.5 7.8 2.3 8.2 3.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.12 EMC92189.1 - 0.014 15.0 4.8 0.085 12.5 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF3496 PF12001.3 EMC92189.1 - 0.026 14.7 0.4 0.041 14.1 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) FlaC_arch PF05377.6 EMC92189.1 - 0.037 13.9 3.2 0.78 9.6 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_MT_bd PF06657.8 EMC92189.1 - 0.044 13.7 0.3 0.044 13.7 0.2 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PilJ PF13675.1 EMC92189.1 - 0.066 13.5 3.6 3 8.1 2.5 2.2 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ubiq_cyt_C_chap PF03981.7 EMC92189.1 - 0.073 12.9 0.2 0.14 12.0 0.0 1.5 2 0 0 2 2 1 0 Ubiquinol-cytochrome C chaperone PspA_IM30 PF04012.7 EMC92189.1 - 0.095 12.0 6.8 0.098 11.9 0.1 2.1 2 0 0 2 2 2 0 PspA/IM30 family GAS PF13851.1 EMC92189.1 - 0.12 11.5 7.0 1.4 8.0 2.8 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CobN-Mg_chel PF02514.11 EMC92189.1 - 0.13 9.5 1.2 0.16 9.2 0.9 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Syntaxin PF00804.20 EMC92189.1 - 0.14 12.3 4.8 4.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Syntaxin YjgP_YjgQ PF03739.9 EMC92189.1 - 0.14 10.8 0.4 0.15 10.7 0.3 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF3338 PF11819.3 EMC92189.1 - 0.14 11.5 5.1 4.5 6.7 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) bZIP_1 PF00170.16 EMC92189.1 - 0.15 11.9 0.3 0.15 11.9 0.2 2.5 2 1 0 2 2 2 0 bZIP transcription factor Laminin_II PF06009.7 EMC92189.1 - 0.17 11.6 1.9 0.53 10.0 1.3 1.8 1 1 0 1 1 1 0 Laminin Domain II Spc24 PF08286.6 EMC92189.1 - 0.27 10.9 5.4 6.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Nnf1 PF03980.9 EMC92189.1 - 0.38 10.7 5.3 0.66 9.9 3.7 1.4 1 1 0 1 1 1 0 Nnf1 Adeno_PIX PF03955.9 EMC92189.1 - 0.4 11.2 2.2 21 5.7 0.0 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Mnd1 PF03962.10 EMC92189.1 - 0.41 10.2 10.5 3.3 7.3 5.1 2.0 1 1 1 2 2 2 0 Mnd1 family DUF1664 PF07889.7 EMC92189.1 - 0.43 10.3 2.7 1.6 8.5 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tektin PF03148.9 EMC92189.1 - 0.48 8.9 9.7 0.12 10.8 0.2 2.0 1 1 1 2 2 2 0 Tektin family DUF342 PF03961.8 EMC92189.1 - 0.67 8.2 7.3 2.5 6.4 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Cluap1 PF10234.4 EMC92189.1 - 1 8.4 8.7 0.85 8.7 2.7 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 TBPIP PF07106.8 EMC92189.1 - 1.2 8.7 10.9 0.4 10.2 0.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 EMC92189.1 - 1.2 8.0 7.4 3.2 6.6 5.2 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0449 PF15136.1 EMC92189.1 - 1.3 9.2 7.0 2.8 8.2 2.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 IncA PF04156.9 EMC92189.1 - 1.4 8.4 16.3 3 7.3 11.3 1.5 1 1 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EMC92189.1 - 1.9 9.0 8.8 1.2 9.6 0.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4559 PF15112.1 EMC92189.1 - 1.9 7.5 6.9 3.4 6.7 4.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) EMP24_GP25L PF01105.19 EMC92189.1 - 1.9 8.1 6.0 15 5.2 4.2 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.6 EMC92189.1 - 1.9 7.0 9.8 6.8 5.2 6.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Bap31 PF05529.7 EMC92189.1 - 2.4 7.5 5.0 35 3.7 2.5 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like WD40_alt PF14077.1 EMC92189.1 - 4.3 7.0 7.8 0.61 9.7 0.1 2.7 2 1 1 3 3 3 0 Alternative WD40 repeat motif DivIC PF04977.10 EMC92189.1 - 5.6 6.5 8.2 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.11 EMC92190.1 - 3.1e-35 121.5 37.4 3.1e-35 121.5 25.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC92190.1 - 1.4e-13 50.3 9.6 1.4e-13 50.3 6.7 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EMC92190.1 - 0.0068 14.5 1.8 0.0068 14.5 1.2 2.5 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.8 EMC92190.1 - 0.056 13.8 0.0 0.21 12.0 0.0 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ATG27 PF09451.5 EMC92192.1 - 2.8e-66 223.5 0.0 3.4e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EMC92192.1 - 2.9e-05 23.8 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Syja_N PF02383.13 EMC92193.1 - 2.1e-89 299.4 0.0 3.3e-89 298.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EMC92193.1 - 1.2e-30 105.1 0.0 2.8e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase Cupin_2 PF07883.6 EMC92194.1 - 6.7e-14 51.1 0.3 1.6e-13 49.9 0.2 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EMC92194.1 - 4.2e-07 29.5 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.3 EMC92194.1 - 0.0019 18.1 0.0 0.0073 16.2 0.0 1.8 1 1 0 1 1 1 1 Mif2/CENP-C like Cupin_3 PF05899.7 EMC92194.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SNF2_N PF00176.18 EMC92195.1 - 8.5e-66 221.7 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC92195.1 - 2.7e-13 49.5 0.0 5.9e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC92195.1 - 2.4e-06 27.1 0.1 9.4e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMC92195.1 - 3.9e-05 23.5 0.0 8.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EMC92195.1 - 0.00035 19.4 0.0 0.0016 17.3 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Nucleo_P87 PF07267.6 EMC92196.1 - 3.2 6.3 4.6 1.8 7.1 1.6 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TraB PF01963.12 EMC92197.1 - 0.086 12.2 0.9 0.12 11.8 0.6 1.2 1 0 0 1 1 1 0 TraB family PfkB PF00294.19 EMC92199.1 - 9e-69 231.8 0.0 1e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMC92199.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF221 PF02714.10 EMC92200.1 - 1.7e-105 352.5 29.3 2.6e-105 351.8 20.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMC92200.1 - 5.9e-40 136.4 0.8 5.9e-40 136.4 0.6 3.1 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMC92200.1 - 1.4e-15 56.9 0.0 2.1e-10 40.3 0.0 2.6 1 1 1 2 2 2 2 Phosphate metabolism protein DUF4463 PF14703.1 EMC92200.1 - 3.6e-10 40.2 9.3 9.4e-06 26.0 3.6 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) FAD_binding_3 PF01494.14 EMC92201.1 - 1.2e-07 31.1 4.8 0.00042 19.4 0.5 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EMC92201.1 - 0.096 13.1 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNR_inhib PF08591.5 EMC92202.1 - 1e-16 61.5 0.4 2.3e-16 60.4 0.0 1.8 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor HEAT PF02985.17 EMC92203.1 - 4e-18 63.7 9.5 7.8e-05 22.4 0.0 10.4 13 0 0 13 13 11 2 HEAT repeat HEAT_2 PF13646.1 EMC92203.1 - 7.5e-17 61.3 17.0 6.6e-07 29.5 0.0 8.0 3 2 7 10 10 10 7 HEAT repeats HEAT_EZ PF13513.1 EMC92203.1 - 6.5e-16 58.2 16.2 1.5e-08 34.8 0.0 9.6 7 3 2 9 9 9 2 HEAT-like repeat IBN_N PF03810.14 EMC92203.1 - 2.7e-10 40.0 4.7 4.8e-09 35.9 0.3 4.0 4 1 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EMC92203.1 - 4.8e-08 32.6 4.6 0.0095 15.3 0.0 5.1 5 1 1 6 6 6 3 CLASP N terminal MMS19_C PF12460.3 EMC92203.1 - 1.7e-07 30.3 3.3 0.00034 19.4 1.7 3.5 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EMC92203.1 - 2.4e-07 30.5 2.8 0.0013 18.3 0.0 5.6 2 1 4 7 7 7 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 EMC92203.1 - 1.8e-06 26.6 0.1 0.0007 18.0 0.0 3.9 2 1 1 3 3 3 2 Adaptin N terminal region Arm PF00514.18 EMC92203.1 - 3.5e-06 26.6 4.2 1.7 8.5 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF3554 PF12074.3 EMC92203.1 - 0.0065 15.9 1.1 0.092 12.1 0.5 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3554) HEAT_PBS PF03130.11 EMC92203.1 - 0.021 15.2 5.2 8.7 7.1 0.0 6.1 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat ATP12 PF07542.6 EMC92205.1 - 1.1e-35 122.2 2.4 1.1e-35 122.2 0.0 2.1 3 0 0 3 3 3 1 ATP12 chaperone protein Fungal_trans PF04082.13 EMC92206.1 - 4.1e-27 94.6 0.0 6.7e-26 90.7 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC92206.1 - 3.3e-07 30.1 7.3 5.7e-07 29.3 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1989 PF09347.5 EMC92207.1 - 9.6e-55 184.5 0.0 1.2e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Ins_beta PF03488.9 EMC92211.1 - 5.9 6.7 7.2 0.27 11.0 1.3 1.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type PHD PF00628.24 EMC92212.1 - 9.7e-05 21.9 8.7 0.00069 19.2 6.1 2.1 1 1 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 EMC92212.1 - 0.0029 17.5 1.2 0.0075 16.2 0.8 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-Apc11 PF12861.2 EMC92212.1 - 0.088 12.6 0.9 0.17 11.7 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.1 EMC92212.1 - 0.38 10.9 5.1 0.92 9.6 3.5 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain VSP PF03302.8 EMC92213.1 - 4.4 5.8 8.7 0.37 9.3 2.4 1.6 1 1 0 2 2 2 0 Giardia variant-specific surface protein SBDS_C PF09377.5 EMC92215.1 - 6.2e-49 164.8 0.0 8.9e-49 164.3 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EMC92215.1 - 4.7e-28 96.8 0.1 1.2e-27 95.5 0.1 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UBX PF00789.15 EMC92216.1 - 1.2e-12 47.7 0.0 3.1e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EMC92216.1 - 2e-10 40.0 0.7 4.2e-10 38.9 0.5 1.5 1 0 0 1 1 1 1 UBA-like domain DUF1682 PF07946.9 EMC92216.1 - 0.05 12.4 5.0 0.086 11.6 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDHD PF02862.12 EMC92216.1 - 0.56 9.9 4.0 1.1 9.0 2.8 1.4 1 0 0 1 1 1 0 DDHD domain Pkinase PF00069.20 EMC92217.1 - 3.7e-06 26.3 0.0 7.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92217.1 - 0.04 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3632 PF12311.3 EMC92218.1 - 3.1e-32 111.8 2.2 3.1e-32 111.8 1.5 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF3632) SRP19 PF01922.12 EMC92219.1 - 1.1e-27 96.4 0.0 1.6e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Pkinase PF00069.20 EMC92220.1 - 1.4e-54 184.9 0.0 2e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92220.1 - 1e-14 54.2 0.0 7.4e-14 51.4 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase NeA_P2 PF12312.3 EMC92220.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CPSF73-100_C PF11718.3 EMC92221.1 - 1.6e-66 223.7 0.0 2.3e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EMC92221.1 - 1.1e-32 112.6 0.0 2.4e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EMC92221.1 - 8.5e-17 61.4 1.7 1.6e-16 60.5 1.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC92221.1 - 1.3e-10 41.1 0.8 2.5e-10 40.2 0.6 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EMC92221.1 - 2.9e-09 36.6 0.1 7.2e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EMC92221.1 - 9.4e-06 25.4 0.5 3.5e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PQ-loop PF04193.9 EMC92223.1 - 1.4e-09 37.3 15.2 3.9e-05 23.1 0.1 3.3 3 1 0 3 3 3 2 PQ loop repeat NAM-associated PF14303.1 EMC92224.1 - 0.083 13.2 10.1 0.14 12.4 7.0 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Catalase PF00199.14 EMC92225.1 - 2.3e-11 43.0 3.6 2.3e-10 39.7 2.5 2.0 1 1 0 1 1 1 1 Catalase DUF1214 PF06742.6 EMC92225.1 - 0.082 13.3 0.1 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1214) DUF630 PF04783.7 EMC92225.1 - 0.15 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF630) DUF373 PF04123.8 EMC92226.1 - 0.21 10.5 4.4 0.3 10.0 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) CybS PF05328.7 EMC92226.1 - 0.33 10.5 2.2 0.6 9.7 1.5 1.4 1 1 0 1 1 1 0 CybS ALO PF04030.9 EMC92227.1 - 6.3e-81 271.7 1.3 9.3e-81 271.2 0.9 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EMC92227.1 - 8.8e-31 106.2 0.0 1.5e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain His_Phos_1 PF00300.17 EMC92228.1 - 4.7e-13 49.5 0.0 6.7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GST_N_3 PF13417.1 EMC92230.1 - 3.8e-08 33.4 0.0 7.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC92230.1 - 3e-07 30.8 0.0 4.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC92230.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC92230.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC92230.1 - 0.0015 18.4 0.1 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MoaC PF01967.16 EMC92231.1 - 2.7e-49 166.3 0.8 4.8e-49 165.5 0.5 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EMC92231.1 - 2.5e-34 117.7 0.0 1e-33 115.7 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EMC92231.1 - 2.8e-21 76.4 0.0 4.8e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EMC92231.1 - 1e-06 28.9 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMC92231.1 - 9.1e-06 25.6 0.0 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Mito_fiss_reg PF05308.6 EMC92231.1 - 1.2 8.4 5.1 4.5 6.5 3.6 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Acetyltransf_1 PF00583.19 EMC92232.1 - 1.4e-07 31.4 0.0 6.1e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EMC92232.1 - 0.00034 21.1 0.0 0.0016 18.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC92232.1 - 0.0052 16.6 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DD_K PF12121.3 EMC92234.1 - 0.63 9.9 3.9 3.6 7.5 0.1 2.7 2 0 0 2 2 2 0 Dermaseptin DUF3739 PF12545.3 EMC92235.1 - 0.052 13.6 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein N2227 PF07942.7 EMC92236.1 - 4.1e-88 294.8 0.0 4.9e-88 294.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EMC92236.1 - 0.019 14.7 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_3 PF00202.16 EMC92237.1 - 7.3e-80 268.3 0.0 9.9e-80 267.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III MSA-2c PF12238.3 EMC92238.1 - 2.9 7.4 6.7 0.19 11.3 1.4 1.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c Exo_endo_phos PF03372.18 EMC92239.1 - 6.5e-10 39.3 0.8 8.9e-10 38.9 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMC92239.1 - 4.2e-07 29.6 0.0 3.4e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Asp PF00026.18 EMC92240.1 - 2.5e-71 240.5 13.9 3e-71 240.2 9.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EMC92240.1 - 9.1e-05 22.8 3.4 0.022 15.2 0.5 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMC92240.1 - 0.0018 17.8 0.2 0.012 15.2 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EMC92240.1 - 0.0032 17.4 2.8 0.0061 16.5 1.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal PDEase_II PF02112.10 EMC92241.1 - 3.6e-50 170.8 0.0 7.7e-45 153.2 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EMC92241.1 - 0.00046 19.8 0.0 0.00096 18.7 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC92241.1 - 0.42 10.2 5.4 1 8.9 3.7 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Metallophos PF00149.23 EMC92242.1 - 3.4e-20 72.3 0.0 8.1e-20 71.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EMC92242.1 - 1.5e-13 50.5 0.0 3.9e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EMC92242.1 - 6.2e-08 31.6 0.2 2.1e-07 29.9 0.2 1.7 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EMC92242.1 - 0.002 18.0 0.0 0.0048 16.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 EMC92242.1 - 0.046 13.8 0.4 0.09 12.9 0.3 1.4 1 0 0 1 1 1 0 Fibronectin type III domain AA_permease_2 PF13520.1 EMC92243.1 - 1.5e-57 195.0 50.2 1.9e-57 194.7 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC92243.1 - 8.7e-23 80.3 44.2 1.2e-22 79.9 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease Neur_chan_memb PF02932.11 EMC92243.1 - 4.4 7.1 5.6 3.5 7.4 0.0 2.9 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region C8 PF08742.6 EMC92244.1 - 0.086 13.0 1.8 0.11 12.7 1.3 1.1 1 0 0 1 1 1 0 C8 domain Mito_carr PF00153.22 EMC92245.1 - 7.3e-44 147.4 8.5 2.7e-16 59.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein K_oxygenase PF13434.1 EMC92246.1 - 2.6e-16 59.4 0.0 8.3e-11 41.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EMC92246.1 - 4.9e-13 49.6 0.0 8e-08 32.5 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC92246.1 - 7.1e-08 31.7 1.2 0.051 12.4 0.1 3.4 3 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC92246.1 - 1.3e-06 28.2 0.1 0.065 12.9 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EMC92246.1 - 5.1e-06 25.7 0.0 0.0079 15.2 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EMC92246.1 - 6.7e-06 26.1 0.0 0.11 12.3 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC92246.1 - 0.00061 18.8 0.1 0.0076 15.2 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMC92246.1 - 0.00065 19.6 0.4 0.019 14.9 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EMC92246.1 - 0.00076 19.5 0.0 0.099 12.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EMC92246.1 - 0.0045 15.8 0.0 0.14 11.0 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 EMC92246.1 - 0.0076 16.6 0.0 3.6 8.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC92246.1 - 0.01 14.3 0.0 0.66 8.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EMC92246.1 - 0.051 12.6 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family 2_5_RNA_ligase2 PF13563.1 EMC92246.1 - 0.067 12.8 0.0 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily TrkA_N PF02254.13 EMC92246.1 - 0.15 12.0 0.1 0.88 9.5 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Peptidase_S10 PF00450.17 EMC92247.1 - 1.9e-100 336.9 2.4 2.3e-100 336.7 1.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase APC10 PF03256.11 EMC92248.1 - 2.3e-40 138.2 0.0 2.5e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Alpha-amylase PF00128.19 EMC92249.1 - 6.1e-27 94.8 0.0 9e-17 61.4 0.0 2.2 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Zn_clus PF00172.13 EMC92251.1 - 1.3e-07 31.3 11.5 2e-07 30.7 8.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMC92251.1 - 2.2e-07 29.8 1.8 4.1e-07 28.9 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain A_deaminase PF00962.17 EMC92252.1 - 4.2e-69 233.0 0.0 4.7e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase HMGL-like PF00682.14 EMC92255.1 - 3.4e-62 210.1 0.0 5.7e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EMC92255.1 - 2.3e-20 72.7 0.3 2.6e-19 69.3 0.2 2.3 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_60s PF00428.14 EMC92255.1 - 0.0037 17.6 1.2 0.77 10.1 0.0 2.8 2 0 0 2 2 2 2 60s Acidic ribosomal protein HSP20 PF00011.16 EMC92257.1 - 3.8e-12 45.9 0.3 5.3e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PP2C PF00481.16 EMC92260.1 - 6.7e-37 127.2 0.0 4.5e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EMC92260.1 - 1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMC92260.1 - 0.1 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Epimerase PF01370.16 EMC92261.1 - 2e-12 47.0 0.0 3.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC92261.1 - 2.8e-10 40.5 0.1 7.2e-10 39.1 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMC92261.1 - 1.3e-08 33.9 0.0 2.8e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMC92261.1 - 2.1e-08 33.4 0.3 6.4e-07 28.5 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EMC92261.1 - 9.6e-07 28.2 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EMC92261.1 - 0.07 13.0 1.7 1.1 9.2 1.2 2.3 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMC92261.1 - 0.094 11.5 0.0 2.8 6.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EMC92261.1 - 0.16 11.6 0.5 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 KR domain PhoD PF09423.5 EMC92262.1 - 4.7e-154 513.3 5.5 5.4e-154 513.0 3.8 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase CENP-X PF09415.5 EMC92263.1 - 1e-22 79.6 0.2 1.8e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DUF4611 PF15387.1 EMC92263.1 - 4.5 7.4 6.8 1.9 8.7 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF745 PF05335.8 EMC92264.1 - 0.031 13.7 0.6 0.044 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Mis12 PF05859.7 EMC92265.1 - 1.6e-32 112.2 0.5 1.6e-32 112.2 0.3 1.6 2 0 0 2 2 2 1 Mis12 protein VWA PF00092.23 EMC92266.1 - 9.5e-09 35.2 0.0 3.7e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC92266.1 - 5.8e-08 33.0 0.0 9.8e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EMC92266.1 - 0.00027 20.8 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 EMC92266.1 - 0.0095 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FTR1 PF03239.9 EMC92269.1 - 9.8e-87 290.7 6.8 1.2e-86 290.4 4.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Wzy_C PF04932.10 EMC92269.1 - 0.089 12.5 6.3 1.5 8.5 0.4 2.5 2 0 0 2 2 2 0 O-Antigen ligase Acetate_kinase PF00871.12 EMC92269.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Acetokinase family Cu-oxidase_2 PF07731.9 EMC92270.1 - 6e-48 161.8 7.3 5.8e-41 139.2 0.5 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMC92270.1 - 1.4e-42 144.1 7.1 7.4e-39 132.1 0.8 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EMC92270.1 - 8.7e-41 139.4 0.7 1.5e-34 119.1 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EMC92270.1 - 0.00041 20.2 0.0 0.69 9.8 0.0 3.5 3 0 0 3 3 3 1 Cupredoxin-like domain C1q PF00386.16 EMC92270.1 - 0.093 12.7 0.0 2.7 7.9 0.0 2.9 2 1 2 4 4 4 0 C1q domain OMPdecase PF00215.19 EMC92271.1 - 2e-76 256.3 0.0 2.4e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HD_4 PF13328.1 EMC92273.1 - 0.07 12.8 0.4 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 HD domain DUF2267 PF10025.4 EMC92273.1 - 0.13 12.3 0.2 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) PHD PF00628.24 EMC92274.1 - 0.0028 17.2 11.3 0.0046 16.6 7.9 1.3 1 0 0 1 1 1 1 PHD-finger Rotamase PF00639.16 EMC92274.1 - 0.077 13.7 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain Erp_C PF06780.6 EMC92276.1 - 0.4 10.5 5.6 0.41 10.4 2.5 2.0 1 1 0 1 1 1 0 Erp protein C-terminus Glycos_transf_1 PF00534.15 EMC92277.1 - 3.8e-18 65.4 0.0 7e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMC92277.1 - 7.7e-08 32.5 0.0 2e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMC92277.1 - 3e-05 24.2 0.0 7.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Chitin_bind_4 PF00379.18 EMC92277.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Insect cuticle protein Iso_dh PF00180.15 EMC92278.1 - 4.4e-94 315.2 0.0 5e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1572 PF07609.6 EMC92279.1 - 0.19 11.2 2.8 0.1 12.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) APG6 PF04111.7 EMC92279.1 - 1.4 7.8 32.3 4.5 6.2 1.6 3.0 2 1 0 2 2 2 0 Autophagy protein Apg6 Prefoldin PF02996.12 EMC92279.1 - 5.1 6.7 14.6 0.62 9.7 1.1 3.8 3 0 0 3 3 3 0 Prefoldin subunit ATG16 PF08614.6 EMC92279.1 - 8.2 6.2 29.0 0.55 10.0 6.1 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) HALZ PF02183.13 EMC92281.1 - 0.014 15.1 1.5 0.014 15.1 1.0 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper HJURP_C PF12347.3 EMC92281.1 - 0.019 14.5 0.8 0.024 14.2 0.4 1.5 1 1 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Tup_N PF08581.5 EMC92281.1 - 0.071 13.3 2.6 1.3 9.2 0.1 2.1 2 0 0 2 2 2 0 Tup N-terminal DivIC PF04977.10 EMC92281.1 - 0.17 11.4 3.2 4.6 6.7 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator APG6 PF04111.7 EMC92281.1 - 0.37 9.7 2.2 0.43 9.5 1.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 EMC92281.1 - 0.45 10.4 3.2 14 5.6 0.3 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 BRE1 PF08647.6 EMC92281.1 - 0.93 9.5 4.8 1.4 8.9 2.9 1.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.1 EMC92281.1 - 0.98 8.5 6.2 2.5 7.2 4.3 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MT0933_antitox PF14013.1 EMC92282.1 - 0.48 10.5 5.9 0.28 11.3 1.5 2.3 2 1 0 2 2 2 0 MT0933-like antitoxin protein DUF3586 PF12131.3 EMC92285.1 - 0.06 13.3 0.3 0.092 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Acetyltransf_4 PF13420.1 EMC92286.1 - 0.00012 22.0 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Arf PF00025.16 EMC92287.1 - 1.3e-65 219.9 1.6 1.4e-65 219.7 1.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC92287.1 - 3.9e-12 45.5 1.5 9.5e-07 27.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMC92287.1 - 7e-12 45.0 0.0 8e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC92287.1 - 1.5e-09 37.3 0.0 1.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC92287.1 - 1.3e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC92287.1 - 1.3e-08 35.3 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EMC92287.1 - 1.9e-08 33.7 0.0 2.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMC92287.1 - 6.4e-06 25.7 0.1 0.00058 19.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EMC92287.1 - 0.0016 19.2 0.0 0.0021 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EMC92287.1 - 0.014 14.7 0.5 0.044 13.0 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2617 PF10936.3 EMC92287.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2617 PduV-EutP PF10662.4 EMC92287.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EMC92287.1 - 0.054 13.8 0.1 0.081 13.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMC92287.1 - 0.082 12.6 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 NTPase 6PF2K PF01591.13 EMC92287.1 - 0.091 11.8 0.1 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Gelsolin PF00626.17 EMC92288.1 - 1.8e-08 33.9 0.0 0.072 12.7 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat CN_hydrolase PF00795.17 EMC92289.1 - 2.4e-22 79.2 0.0 3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Gene66 PF02053.10 EMC92289.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein Cellulase PF00150.13 EMC92290.1 - 7.3e-53 179.5 0.1 1.1e-52 179.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EMC92290.1 - 8.8e-13 47.6 12.3 3.2e-12 45.8 8.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain CDP-OH_P_transf PF01066.16 EMC92291.1 - 2e-17 63.3 3.0 2e-17 63.3 2.1 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF423 PF04241.10 EMC92291.1 - 0.044 13.7 0.7 0.13 12.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF423) AAA_2 PF07724.9 EMC92292.1 - 3.3e-47 160.5 0.0 1.9e-45 154.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EMC92292.1 - 1.9e-27 96.0 0.0 8.3e-15 55.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EMC92292.1 - 4.4e-24 84.1 0.3 1.5e-23 82.4 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EMC92292.1 - 8.7e-17 61.6 11.2 1.7e-06 28.1 0.0 6.3 4 2 3 7 7 6 2 AAA ATPase domain AAA_5 PF07728.9 EMC92292.1 - 6.9e-16 58.2 0.1 7.9e-10 38.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMC92292.1 - 1.4e-14 54.3 0.0 2.7e-05 24.3 0.0 4.0 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EMC92292.1 - 3.6e-09 37.4 0.9 0.0073 17.1 0.0 3.6 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EMC92292.1 - 7.6e-09 35.2 0.0 4.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMC92292.1 - 3.1e-07 29.9 0.0 0.033 13.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EMC92292.1 - 3.5e-07 29.8 0.1 0.026 14.2 0.1 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EMC92292.1 - 1.1e-06 28.9 2.0 0.023 14.9 0.0 3.5 3 1 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 EMC92292.1 - 1e-05 24.8 0.2 0.096 11.8 0.0 3.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMC92292.1 - 1.5e-05 24.9 0.1 0.27 11.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 EMC92292.1 - 1.8e-05 23.7 0.0 0.0038 16.1 0.0 2.9 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 EMC92292.1 - 2.1e-05 24.4 0.0 0.12 12.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMC92292.1 - 6.9e-05 22.9 0.0 0.48 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EMC92292.1 - 0.00016 21.4 0.0 0.73 9.5 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EMC92292.1 - 0.00017 21.2 0.0 0.97 9.0 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMC92292.1 - 0.00029 20.2 0.0 1.5 8.1 0.0 3.5 2 1 0 3 3 3 2 AAA domain Clp_N PF02861.15 EMC92292.1 - 0.00033 20.5 0.3 0.11 12.4 0.0 3.7 3 0 0 3 3 3 1 Clp amino terminal domain AAA_29 PF13555.1 EMC92292.1 - 0.00068 19.1 0.0 0.37 10.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EMC92292.1 - 0.00098 18.3 0.0 0.48 9.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EMC92292.1 - 0.001 18.7 13.4 0.013 15.1 0.7 5.4 4 2 1 5 5 5 1 Archaeal ATPase AAA_24 PF13479.1 EMC92292.1 - 0.0014 18.3 0.0 0.84 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMC92292.1 - 0.0018 17.7 6.3 0.83 9.0 0.0 4.8 5 1 0 5 5 5 1 AAA-like domain ABC_tran PF00005.22 EMC92292.1 - 0.002 18.4 2.9 0.77 10.0 0.0 3.6 4 0 0 4 4 3 1 ABC transporter ResIII PF04851.10 EMC92292.1 - 0.0025 17.6 3.3 0.76 9.5 0.0 4.2 3 1 0 4 4 4 1 Type III restriction enzyme, res subunit NACHT PF05729.7 EMC92292.1 - 0.0039 16.8 0.0 0.32 10.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 EMC92292.1 - 0.0046 16.6 0.2 0.18 11.5 0.0 3.0 3 0 0 3 3 3 1 NTPase Torsin PF06309.6 EMC92292.1 - 0.0047 16.8 0.0 0.068 13.0 0.0 2.6 3 0 0 3 3 3 1 Torsin SRP54 PF00448.17 EMC92292.1 - 0.0087 15.5 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EMC92292.1 - 0.028 14.3 0.0 2.9 7.7 0.0 3.1 4 0 0 4 4 3 0 AAA domain UPF0079 PF02367.12 EMC92292.1 - 0.029 13.9 0.0 8.3 6.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EMC92292.1 - 0.037 13.5 0.0 9.4 5.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EMC92292.1 - 0.072 12.5 0.0 5.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EMC92292.1 - 0.1 12.5 0.0 2.4 8.1 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_11 PF13086.1 EMC92292.1 - 0.15 11.6 17.9 7.6 6.0 0.0 4.1 2 1 0 2 2 2 0 AAA domain MalF_P2 PF14785.1 EMC92292.1 - 0.46 10.3 4.0 1 9.1 2.8 1.6 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain V_ATPase_I PF01496.14 EMC92292.1 - 0.79 7.5 8.7 1.4 6.7 6.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Amidase PF01425.16 EMC92294.1 - 2.5e-92 310.0 0.0 3e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 Amidase His_Phos_2 PF00328.17 EMC92295.1 - 2.6e-26 92.7 0.0 1.3e-25 90.4 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPR_2 PF13041.1 EMC92296.1 - 9.9e-26 89.4 0.6 1.6e-09 37.5 0.0 6.6 6 1 1 7 7 7 4 PPR repeat family PPR PF01535.15 EMC92296.1 - 4.2e-12 45.1 1.7 3.4e-06 26.6 0.2 5.5 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.1 EMC92296.1 - 1.1e-10 40.9 14.0 0.13 12.6 0.0 8.3 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EMC92296.1 - 1.2e-10 40.6 0.0 7.3e-06 25.3 0.0 5.2 6 0 0 6 6 6 2 PPR repeat SH3_3 PF08239.6 EMC92296.1 - 0.054 13.7 0.1 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Spt20 PF12090.3 EMC92297.1 - 3e-34 117.9 0.0 3e-34 117.9 0.0 5.6 3 2 0 3 3 3 1 Spt20 family Lactamase_B_2 PF12706.2 EMC92298.1 - 1.8e-30 105.9 0.0 3.5e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EMC92298.1 - 4.8e-21 73.9 0.0 9.6e-21 73.0 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EMC92298.1 - 6.7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.17 EMC92299.1 - 3.1e-45 151.6 1.7 1.1e-20 73.0 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC92299.1 - 9.2e-33 112.0 0.3 9.4e-18 63.9 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EMC92299.1 - 3.8e-24 84.7 0.1 1.1e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EMC92299.1 - 4.1e-22 77.7 0.3 9e-08 31.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC92299.1 - 2e-05 24.4 0.4 0.0097 15.7 0.0 3.7 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EMC92299.1 - 0.095 12.4 0.0 1.5 8.6 0.0 2.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif zf-B_box PF00643.19 EMC92302.1 - 0.019 14.8 1.5 0.85 9.5 0.1 2.8 3 0 0 3 3 3 0 B-box zinc finger DUF3328 PF11807.3 EMC92303.1 - 1.5e-33 116.3 0.1 2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TBPIP PF07106.8 EMC92305.1 - 0.0013 18.2 1.9 0.0013 18.2 1.3 1.8 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MFS_1 PF07690.11 EMC92306.1 - 3.6e-33 114.7 30.6 3.6e-33 114.7 21.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC92306.1 - 1.4e-14 53.5 5.0 1.4e-14 53.5 3.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Ribosomal_S13 PF00416.17 EMC92307.1 - 8e-41 138.8 1.5 9.7e-41 138.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EMC92307.1 - 0.0026 16.3 0.0 0.005 15.4 0.0 1.5 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EMC92307.1 - 0.095 12.7 0.5 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 zf-Mss51 PF13824.1 EMC92309.1 - 3e-24 84.6 5.3 5.9e-24 83.6 3.7 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 CPSF_A PF03178.10 EMC92310.1 - 3.6e-89 299.0 0.0 1.5e-88 296.9 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EMC92310.1 - 6.6e-45 153.2 0.0 9.2e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EMC92310.1 - 0.06 13.2 0.0 0.98 9.4 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat EF1G PF00647.14 EMC92311.1 - 2.7e-44 149.2 0.0 4.6e-44 148.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EMC92311.1 - 1.1e-09 38.0 0.0 1.1e-09 38.0 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC92311.1 - 4.9e-09 36.2 0.0 1.8e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMC92311.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC92311.1 - 2.5e-06 27.2 0.0 8.1e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC92311.1 - 1.8e-05 25.1 0.1 4.7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC92311.1 - 0.026 14.5 0.0 0.075 13.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pox_Ag35 PF03286.9 EMC92311.1 - 0.79 9.2 8.7 1.2 8.6 6.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 EMC92311.1 - 1.6 8.3 4.0 3.7 7.2 2.8 1.6 1 0 0 1 1 1 0 FAM176 family Ribosomal_S9 PF00380.14 EMC92312.1 - 1.2e-36 125.5 1.4 1.3e-36 125.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S9/S16 HMG_box PF00505.14 EMC92313.1 - 1.8e-15 56.9 2.1 3.8e-15 55.9 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Mtc PF03820.12 EMC92314.1 - 2e-109 364.9 0.1 1.3e-108 362.3 0.1 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier PS_Dcarbxylase PF02666.10 EMC92315.1 - 1.3e-81 272.6 0.0 7.2e-81 270.3 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase SAD_SRA PF02182.12 EMC92317.1 - 2.1e-06 27.1 0.0 2.9e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 SAD/SRA domain DUF3884 PF13024.1 EMC92317.1 - 0.11 11.9 0.1 0.95 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) E1-E2_ATPase PF00122.15 EMC92318.1 - 2.3e-49 167.5 0.2 5.2e-49 166.3 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC92318.1 - 1.9e-39 135.0 5.3 1.9e-39 135.0 3.7 3.0 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMC92318.1 - 1.5e-31 110.4 0.0 5.6e-31 108.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC92318.1 - 3e-20 73.2 0.1 5.2e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC92318.1 - 2.8e-17 62.4 0.0 5.7e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMC92318.1 - 1.2e-10 40.6 0.0 4.6e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMC92318.1 - 5.8e-05 22.7 0.2 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PAP2 PF01569.16 EMC92319.1 - 7.7e-22 77.3 4.1 1.3e-21 76.6 2.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EMC92319.1 - 0.015 15.5 0.1 0.015 15.5 0.1 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Polysacc_synt_C PF14667.1 EMC92319.1 - 7.1 6.4 13.8 0.82 9.4 1.3 2.9 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain RdRP PF05183.7 EMC92320.1 - 3.4e-91 306.7 0.0 5.5e-91 306.0 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3275 PF11679.3 EMC92320.1 - 0.15 11.6 1.0 0.35 10.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF336 PF03928.9 EMC92321.1 - 5.8e-20 71.4 0.0 7.1e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) TCTP PF00838.12 EMC92322.1 - 1.1e-61 207.6 3.0 1.2e-61 207.4 2.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Tim44 PF04280.10 EMC92322.1 - 0.078 12.9 0.9 0.66 9.9 0.1 2.5 1 1 2 3 3 3 0 Tim44-like domain Ribosomal_S8 PF00410.14 EMC92323.1 - 1.9e-24 85.9 0.1 2.7e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Syndecan PF01034.15 EMC92324.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain DUF605 PF04652.11 EMC92324.1 - 0.35 10.2 14.8 0.49 9.7 10.2 1.2 1 0 0 1 1 1 0 Vta1 like Pol_alpha_B_N PF08418.5 EMC92324.1 - 1.8 8.0 10.5 2.8 7.4 7.3 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal WWbp PF10349.4 EMC92324.1 - 7.1 7.5 14.0 1.4 9.8 4.0 2.5 2 0 0 2 2 2 0 WW-domain ligand protein Gly_transf_sug PF04488.10 EMC92325.1 - 1.5e-10 41.4 0.0 3.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif His_Phos_1 PF00300.17 EMC92326.1 - 1.7e-21 76.9 0.0 3.2e-21 76.0 0.0 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.14 EMC92327.1 - 1.4e-36 124.5 0.1 2e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.12 EMC92328.1 - 5.1e-107 356.0 0.0 7.3e-107 355.5 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EMC92328.1 - 1.6e-06 27.8 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EMC92328.1 - 0.0053 16.3 0.1 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EMC92328.1 - 0.062 12.8 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ferric_reduct PF01794.14 EMC92330.1 - 9e-19 67.7 10.6 9e-19 67.7 7.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMC92330.1 - 3.5e-16 59.4 0.0 1.1e-13 51.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMC92330.1 - 3.4e-11 42.9 0.0 6.9e-10 38.7 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMC92330.1 - 0.11 13.0 0.1 0.3 11.6 0.1 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EMC92330.1 - 0.16 12.1 8.1 0.16 12.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Pkinase PF00069.20 EMC92331.1 - 8.7e-47 159.4 0.0 8.1e-44 149.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92331.1 - 1.2e-29 103.1 0.0 3.1e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC92331.1 - 7e-05 21.9 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMC92331.1 - 0.018 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EMC92331.1 - 0.093 12.4 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMC92331.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mem_trans PF03547.13 EMC92333.1 - 1.1e-48 165.4 0.2 2.5e-48 164.3 0.2 1.5 1 1 0 1 1 1 1 Membrane transport protein Fungal_trans PF04082.13 EMC92334.1 - 2.1e-24 85.8 0.0 4.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC92334.1 - 9.4e-08 31.8 13.1 1.8e-07 30.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 EMC92334.1 - 0.04 13.5 1.3 0.11 12.1 0.9 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pyridoxal_deC PF00282.14 EMC92335.1 - 1.8e-76 257.0 0.0 2.4e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMC92335.1 - 9.3e-05 21.3 0.0 0.00015 20.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Vps39_2 PF10367.4 EMC92336.1 - 3e-07 30.5 0.0 1.8e-06 28.1 0.0 2.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EMC92336.1 - 0.014 15.4 0.0 2.1 8.4 0.0 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.7 EMC92337.1 - 6.9e-83 277.4 0.4 6.9e-83 277.4 0.2 4.3 2 1 3 5 5 4 1 CASP C terminal CtIP_N PF10482.4 EMC92337.1 - 0.011 15.5 0.1 0.011 15.5 0.1 5.0 6 0 0 6 6 6 0 Tumour-suppressor protein CtIP N-terminal domain SMAP PF15477.1 EMC92337.1 - 0.039 14.2 5.7 2.6 8.3 0.0 3.7 3 0 0 3 3 3 0 Small acidic protein family DivIC PF04977.10 EMC92337.1 - 0.087 12.3 0.1 0.038 13.4 0.5 7.6 7 2 1 8 8 8 0 Septum formation initiator DUF972 PF06156.8 EMC92337.1 - 0.28 11.5 0.0 0.28 11.5 0.0 6.6 3 1 3 6 6 6 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EMC92337.1 - 1.4 9.0 0.0 1.4 9.0 0.0 4.7 5 0 0 5 5 5 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EMC92337.1 - 1.7 8.4 57.5 0.73 9.6 0.1 5.3 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Noc2 PF03715.8 EMC92337.1 - 2.8 6.7 7.3 3.1 6.5 1.1 2.6 2 1 0 2 2 2 0 Noc2p family Cortex-I_coil PF09304.5 EMC92337.1 - 3.5 7.7 55.3 0.37 10.8 5.3 6.2 5 1 1 6 6 6 0 Cortexillin I, coiled coil Filament PF00038.16 EMC92337.1 - 3.6 6.9 46.2 1.3 8.4 3.7 5.5 3 1 2 5 5 5 0 Intermediate filament protein Hemerythrin PF01814.18 EMC92337.1 - 4 7.6 18.8 1.6 8.8 0.2 4.7 5 1 0 5 5 5 0 Hemerythrin HHE cation binding domain DUF3455 PF11937.3 EMC92338.1 - 1.7e-44 151.9 0.3 2.4e-44 151.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) AMP-binding PF00501.23 EMC92339.1 - 3.5e-53 180.4 1.4 1.2e-19 70.0 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 EMC92339.1 - 6.1e-09 36.4 0.0 1.8e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EMC92339.1 - 0.21 11.4 0.2 0.52 10.1 0.1 1.6 1 0 0 1 1 1 0 Gas vesicle protein G EST1_DNA_bind PF10373.4 EMC92340.1 - 1.3e-43 149.2 0.0 2e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EMC92340.1 - 1.8e-18 66.7 0.1 4.6e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EMC92340.1 - 0.014 14.9 0.0 0.046 13.3 0.0 1.9 1 0 0 1 1 1 0 TPR repeat FA_hydroxylase PF04116.8 EMC92341.1 - 2.3e-13 50.5 14.1 2.3e-13 50.5 9.8 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C2H2_4 PF13894.1 EMC92342.1 - 0.049 13.9 10.9 0.57 10.6 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC92342.1 - 0.33 11.3 11.8 1.1 9.6 0.1 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type PALP PF00291.20 EMC92343.1 - 2.8e-68 230.3 1.2 3.1e-68 230.2 0.3 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMC92343.1 - 0.046 12.7 0.4 0.098 11.6 0.1 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2000 PF09391.5 EMC92343.1 - 0.13 11.9 0.1 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2000) Sec1 PF00995.18 EMC92345.1 - 5e-156 520.6 0.0 5.8e-156 520.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase_C PF00433.19 EMC92345.1 - 0.058 13.9 0.1 1.6 9.3 0.0 2.8 2 0 0 2 2 2 0 Protein kinase C terminal domain ATG_C PF09333.6 EMC92346.1 - 0.035 14.2 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 ATG C terminal domain DUF3279 PF11682.3 EMC92346.1 - 0.47 10.0 3.4 0.35 10.4 0.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3279) zf-CCCH PF00642.19 EMC92347.1 - 0.0016 18.0 1.5 0.0027 17.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Angiomotin_C PF12240.3 EMC92347.1 - 0.0091 15.5 0.4 0.037 13.5 0.0 2.3 2 0 0 2 2 2 1 Angiomotin C terminal Aldedh PF00171.17 EMC92348.1 - 3.4e-111 371.8 0.8 4.2e-111 371.5 0.6 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sdh5 PF03937.11 EMC92349.1 - 1.8e-14 53.1 0.5 4.9e-14 51.7 0.3 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase DUF4265 PF14085.1 EMC92352.1 - 0.052 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) DEAD PF00270.24 EMC92354.1 - 5.5e-46 156.1 0.0 1.3e-44 151.6 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMC92354.1 - 4.7e-22 77.3 0.1 9.3e-22 76.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMC92354.1 - 1.3e-20 73.0 0.0 1.3e-19 69.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PGA2 PF07543.7 EMC92354.1 - 2.5 7.8 13.6 7 6.4 9.4 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 F-box-like PF12937.2 EMC92355.1 - 0.025 14.3 0.1 0.28 10.9 0.0 2.7 4 0 0 4 4 4 0 F-box-like Glyco_hydro_15 PF00723.16 EMC92356.1 - 1.5e-59 201.7 0.2 2.2e-59 201.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_21 PF03370.8 EMC92356.1 - 0.027 14.4 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Putative phosphatase regulatory subunit FAD_binding_3 PF01494.14 EMC92358.1 - 5.6e-28 98.0 0.0 8.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EMC92358.1 - 1.4e-06 27.3 0.0 2.9e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EMC92358.1 - 1.8e-06 27.1 0.6 0.00053 18.9 0.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC92358.1 - 5.7e-05 23.0 0.3 0.00013 21.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMC92358.1 - 0.0001 21.5 0.1 0.0065 15.5 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMC92358.1 - 0.0026 18.1 0.6 0.0061 16.9 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC92358.1 - 0.0074 16.3 0.0 0.019 15.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EMC92358.1 - 0.009 16.0 0.8 0.77 9.7 0.0 2.7 2 0 0 2 2 2 1 NADH(P)-binding FAD_binding_2 PF00890.19 EMC92358.1 - 0.011 14.6 0.7 0.026 13.4 0.5 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EMC92358.1 - 0.062 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMC92358.1 - 0.15 11.7 0.8 0.76 9.5 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 EMC92358.1 - 0.51 9.1 4.1 3.2 6.5 0.2 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein SH2_2 PF14633.1 EMC92360.1 - 9.5e-78 260.2 0.0 9.5e-78 260.2 0.0 2.6 4 0 0 4 4 3 1 SH2 domain DLD PF14878.1 EMC92360.1 - 3.9e-37 126.8 5.9 3.9e-37 126.8 4.1 3.4 4 0 0 4 4 3 1 Death-like domain of SPT6 YqgF PF14639.1 EMC92360.1 - 1.1e-31 109.4 0.0 4.1e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EMC92360.1 - 2.9e-29 101.2 0.0 6.7e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EMC92360.1 - 1.1e-21 76.8 33.8 1.1e-21 76.8 23.4 5.1 5 0 0 5 5 4 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EMC92360.1 - 7.2e-15 55.0 4.1 2e-13 50.4 2.9 2.8 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 EMC92360.1 - 8.4e-06 25.7 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 EMC92360.1 - 0.0026 17.5 0.0 0.0069 16.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EMC92360.1 - 0.026 14.4 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif CDC27 PF09507.5 EMC92360.1 - 4.6 6.3 31.0 9.6 5.3 21.5 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.5 EMC92360.1 - 9 5.2 30.1 40 3.1 0.0 2.5 2 0 0 2 2 2 0 BUD22 FTHFS PF01268.14 EMC92362.1 - 2.9e-256 850.8 0.1 4.3e-256 850.2 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EMC92362.1 - 1.4e-67 225.7 0.9 3.5e-67 224.5 0.6 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EMC92362.1 - 3.7e-36 123.6 0.8 7.7e-36 122.6 0.6 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.27 EMC92363.1 - 3.3e-31 106.0 0.1 5.2e-08 32.4 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.4 EMC92363.1 - 0.013 14.9 0.4 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EMC92363.1 - 0.02 13.0 0.0 0.14 10.2 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Sugar_tr PF00083.19 EMC92365.1 - 1.4e-83 280.9 18.9 1.7e-83 280.6 13.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC92365.1 - 4.9e-16 58.3 40.8 1.2e-12 47.1 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_76 PF03663.9 EMC92366.1 - 5.2e-113 378.1 19.5 9.7e-113 377.2 13.5 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Sporozoite_P67 PF05642.6 EMC92366.1 - 8.8 4.0 6.3 12 3.6 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4536 PF15055.1 EMC92367.1 - 0.0062 16.5 0.1 0.0062 16.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) Pkinase PF00069.20 EMC92369.1 - 1.4e-69 234.1 0.0 1.8e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92369.1 - 2.6e-31 108.6 0.0 3.7e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC92369.1 - 0.035 13.8 1.7 0.056 13.1 0.1 2.2 2 2 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EMC92369.1 - 0.092 11.7 0.1 0.26 10.3 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_clus PF00172.13 EMC92370.1 - 2.7e-09 36.7 11.1 4.1e-09 36.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EMC92373.1 - 7.9e-17 61.3 0.1 3.4e-05 23.0 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EMC92373.1 - 0.0015 18.4 0.4 0.0067 16.4 0.3 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC92373.1 - 0.05 12.5 0.0 9.8 4.9 0.0 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMC92373.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein TPR_12 PF13424.1 EMC92374.1 - 4.2e-14 52.2 5.2 1e-05 25.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMC92374.1 - 1.2e-06 28.0 6.0 0.35 10.5 1.9 3.5 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 EMC92374.1 - 0.00063 19.4 12.8 0.024 14.5 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC92374.1 - 0.00069 20.2 7.9 0.87 10.3 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC92374.1 - 0.0033 17.3 12.3 0.064 13.2 0.3 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC92374.1 - 0.0053 16.4 0.4 8.3 6.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC92374.1 - 0.016 14.9 0.8 11 6.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC92374.1 - 0.04 13.5 7.6 1 9.0 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc5 PF12862.2 EMC92374.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 EMC92374.1 - 0.073 13.7 12.5 8 7.4 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMC92374.1 - 4.5 7.9 8.1 0.48 11.0 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF159 PF02586.9 EMC92375.1 - 1e-59 201.5 0.0 1.5e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 G_glu_transpept PF01019.16 EMC92376.1 - 6.6e-145 483.4 0.0 7.5e-145 483.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RRM_1 PF00076.17 EMC92377.1 - 1.9e-49 165.1 1.2 2.8e-16 58.8 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC92377.1 - 5e-41 138.5 0.8 8.2e-10 38.5 0.1 5.0 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC92377.1 - 9.4e-21 73.4 0.4 3e-06 26.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC92377.1 - 8.6e-06 25.4 0.0 2 8.2 0.0 3.9 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif NRDE-2 PF08424.5 EMC92377.1 - 0.00091 18.1 0.3 0.00091 18.1 0.2 2.4 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference Lsm_interact PF05391.6 EMC92377.1 - 0.03 13.7 0.0 0.093 12.2 0.0 1.8 1 0 0 1 1 1 0 Lsm interaction motif TPR_14 PF13428.1 EMC92377.1 - 0.046 14.3 7.8 12 6.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.14 EMC92378.1 - 5.1e-16 58.5 0.1 1.7e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e HAD_2 PF13419.1 EMC92379.1 - 1.9e-10 41.2 0.0 1.3e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC92379.1 - 4.8e-08 33.6 0.0 6.7e-05 23.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC92379.1 - 1.8e-07 30.7 0.0 3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EMC92379.1 - 5.8e-06 26.6 0.0 9.8e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ORMDL PF04061.9 EMC92380.1 - 5.1e-60 200.9 5.5 5.9e-60 200.7 3.8 1.0 1 0 0 1 1 1 1 ORMDL family DUF2208 PF09973.4 EMC92380.1 - 0.051 12.8 1.0 0.058 12.6 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) PIG-P PF08510.7 EMC92380.1 - 2.3 7.8 6.5 0.66 9.6 2.0 1.9 1 1 1 2 2 2 0 PIG-P RRM_1 PF00076.17 EMC92381.1 - 2.6e-08 33.3 0.0 4.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trypan_PARP PF05887.6 EMC92381.1 - 5.4e-08 32.7 6.1 1.2e-07 31.6 4.2 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) RRM_6 PF14259.1 EMC92381.1 - 1.3e-06 28.2 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EMC92381.1 - 6.9e-05 22.5 9.0 0.044 13.7 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EMC92381.1 - 0.028 14.1 1.1 0.6 9.8 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.1 EMC92381.1 - 2.2 7.8 4.7 13 5.3 0.4 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CN_hydrolase PF00795.17 EMC92382.1 - 3e-33 114.7 0.2 4.1e-33 114.3 0.2 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NDUFA12 PF05071.11 EMC92383.1 - 4e-12 46.5 1.0 4e-12 46.5 0.7 2.0 1 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ArsA_ATPase PF02374.10 EMC92384.1 - 4.9e-107 357.4 0.0 5.5e-107 357.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EMC92384.1 - 6e-17 61.6 0.2 1e-16 60.9 0.1 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMC92384.1 - 8.8e-08 32.2 0.0 2e-06 27.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EMC92384.1 - 1.8e-06 27.3 0.1 3.6e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EMC92384.1 - 3.6e-06 26.5 0.1 0.00029 20.3 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EMC92384.1 - 0.00088 18.7 0.6 0.0057 16.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMC92384.1 - 0.0022 17.4 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain PhoH PF02562.11 EMC92384.1 - 0.0063 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.12 EMC92384.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMC92384.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain MipZ PF09140.6 EMC92384.1 - 0.019 14.0 0.1 0.052 12.6 0.0 1.7 2 0 0 2 2 2 0 ATPase MipZ Zeta_toxin PF06414.7 EMC92384.1 - 0.02 13.9 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin YhjQ PF06564.7 EMC92384.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 YhjQ protein NB-ARC PF00931.17 EMC92384.1 - 0.053 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.9 EMC92384.1 - 0.065 12.1 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase T2SE PF00437.15 EMC92384.1 - 0.12 11.2 0.0 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein MRC1 PF09444.5 EMC92385.1 - 8.2e-20 71.6 17.6 8.2e-20 71.6 12.2 6.4 5 1 2 7 7 7 1 MRC1-like domain Herpes_U44 PF04533.8 EMC92385.1 - 0.39 9.9 4.3 1.2 8.4 3.0 1.8 1 0 0 1 1 1 0 Herpes virus U44 protein PPR_2 PF13041.1 EMC92386.1 - 2.3e-09 37.0 0.0 8.6e-06 25.6 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EMC92386.1 - 6.9e-05 22.8 0.2 1.2 9.6 0.0 4.1 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 EMC92386.1 - 0.11 12.4 0.0 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 PPR repeat DUF1365 PF07103.6 EMC92389.1 - 1.6e-41 142.0 0.1 4.4e-41 140.6 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) MFS_1 PF07690.11 EMC92391.1 - 6.2e-35 120.5 43.3 6.2e-35 120.5 30.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EMC92391.1 - 0.58 8.1 10.2 0.054 11.5 1.5 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TAF8_C PF10406.4 EMC92393.1 - 3.5e-19 68.5 3.1 4.8e-19 68.1 1.2 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EMC92393.1 - 2.5e-08 33.5 0.0 4.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated adh_short PF00106.20 EMC92395.1 - 6.3e-26 91.2 2.9 7.9e-26 90.9 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92395.1 - 8.9e-26 91.1 0.0 1.1e-25 90.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92395.1 - 8.5e-16 58.1 0.7 1.4e-15 57.4 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC92395.1 - 0.00067 19.7 0.8 0.0013 18.7 0.5 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC92395.1 - 0.015 14.7 0.5 0.025 14.0 0.2 1.6 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMC92395.1 - 0.027 14.2 0.6 0.078 12.7 0.4 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UTP15_C PF09384.5 EMC92396.1 - 4.8e-34 117.1 0.0 7.9e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EMC92396.1 - 8.1e-20 69.9 9.4 1.9e-07 30.7 0.2 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Herpes_UL21 PF03252.8 EMC92396.1 - 0.17 10.2 0.0 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL21 adh_short PF00106.20 EMC92397.1 - 2.4e-22 79.6 0.0 3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92397.1 - 4.5e-11 42.9 0.0 6.2e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92397.1 - 7.1e-07 29.0 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC92397.1 - 1.4e-05 25.1 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC92397.1 - 5.9e-05 22.6 0.1 0.00057 19.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC92397.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EMC92397.1 - 0.0025 17.5 0.1 0.0055 16.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_25 PF13649.1 EMC92397.1 - 0.0027 18.0 0.0 0.016 15.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain NAD_Gly3P_dh_N PF01210.18 EMC92397.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.11 EMC92398.1 - 2.4e-44 151.4 37.4 2.4e-44 151.4 25.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Plectin PF00681.15 EMC92398.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat Opy2 PF09463.5 EMC92399.1 - 3.6e-07 30.1 23.2 6.4e-07 29.3 16.1 1.4 1 0 0 1 1 1 1 Opy2 protein DUF1191 PF06697.7 EMC92399.1 - 0.0015 17.4 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 EMC92399.1 - 0.0015 18.1 0.2 0.0026 17.3 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain DUF2500 PF10694.4 EMC92399.1 - 0.09 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Baculo_11_kDa PF06143.6 EMC92399.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.1 EMC92399.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1517 PF07466.6 EMC92399.1 - 3.3 6.6 0.0 3.3 6.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1517) DUF2797 PF10977.3 EMC92399.1 - 4.4 6.8 4.8 9.4 5.7 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF2347 PF09804.4 EMC92400.1 - 9.6e-84 280.9 0.0 1.4e-83 280.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EMC92400.1 - 2.2e-23 83.2 3.3 2.7e-22 79.7 0.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) SPA PF08616.5 EMC92400.1 - 3.8e-05 23.3 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Aminotran_1_2 PF00155.16 EMC92401.1 - 1.8e-14 53.4 0.0 3.3e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EMC92401.1 - 0.14 10.6 0.0 1.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.2 EMC92403.1 - 7.8e-76 255.1 25.6 5.8e-67 226.1 8.9 3.5 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EMC92403.1 - 8e-09 34.8 3.7 0.0018 17.7 0.0 3.6 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase DEAD PF00270.24 EMC92404.1 - 1e-44 151.9 0.0 1.8e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC92404.1 - 4.6e-25 87.2 0.0 1.3e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EMC92404.1 - 1.1e-06 27.4 2.9 2.1e-06 26.4 0.1 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EMC92404.1 - 0.019 14.8 0.9 0.059 13.1 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Glyoxalase PF00903.20 EMC92404.1 - 0.037 13.9 0.1 0.088 12.7 0.1 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AAA_22 PF13401.1 EMC92404.1 - 0.24 11.5 1.3 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain FAD_binding_4 PF01565.18 EMC92405.1 - 9.9e-27 93.1 0.0 2e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EMC92405.1 - 1.2e-22 80.4 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain 4HBT_3 PF13622.1 EMC92406.1 - 6.4e-51 173.5 1.8 1.6e-50 172.2 1.3 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMC92406.1 - 1.5e-26 92.6 0.0 1.6e-12 47.1 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Stomoxyn PF11585.3 EMC92408.1 - 6.8 6.5 18.5 3.9 7.3 0.8 3.6 3 0 0 3 3 3 0 Insect antimicrobial peptide, stomoxyn LSM PF01423.17 EMC92409.1 - 2.4e-17 62.2 0.3 4.3e-17 61.4 0.2 1.4 2 0 0 2 2 2 1 LSM domain Zn_clus PF00172.13 EMC92410.1 - 0.45 10.4 12.8 1.5 8.8 8.9 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Extensin_2 PF04554.8 EMC92410.1 - 2.7 7.9 9.3 6.3 6.7 6.4 1.6 1 0 0 1 1 1 0 Extensin-like region zf-C2H2 PF00096.21 EMC92412.1 - 1.2 9.6 12.0 0.068 13.5 2.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC92412.1 - 2.6 8.5 10.5 0.22 11.9 2.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Choline_kinase PF01633.15 EMC92414.1 - 1e-59 201.6 0.0 1.5e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EMC92414.1 - 1.5e-15 56.3 0.0 3.5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EMC92414.1 - 2.8e-08 33.8 4.2 2.8e-08 33.8 2.9 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family MFS_1 PF07690.11 EMC92415.1 - 5.7e-34 117.3 72.6 1.7e-33 115.8 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC92415.1 - 1.4e-11 43.6 34.5 2.6e-10 39.4 23.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 EMC92416.1 - 9.7e-40 136.3 0.0 1.4e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMC92416.1 - 0.00032 19.4 0.0 0.00058 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EMC92416.1 - 0.0022 17.7 0.0 0.0067 16.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC92416.1 - 0.0026 17.6 0.3 0.0074 16.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EMC92416.1 - 0.0032 16.8 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 EMC92416.1 - 0.028 13.6 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 EMC92416.1 - 0.054 12.2 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Pox_T4_N PF04491.7 EMC92417.1 - 0.015 15.0 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus Catalase PF00199.14 EMC92419.1 - 8.6e-146 485.5 0.1 1.2e-145 485.0 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMC92419.1 - 3.7e-12 45.9 0.1 7.4e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive TrbC PF04956.8 EMC92421.1 - 0.06 13.3 2.2 2.6 8.1 0.3 2.3 2 0 0 2 2 2 0 TrbC/VIRB2 family COesterase PF00135.23 EMC92424.1 - 3.2e-66 224.1 0.0 4.3e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC92424.1 - 0.00015 21.4 0.0 0.2 11.2 0.0 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC92424.1 - 0.0029 17.3 0.1 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pro_isomerase PF00160.16 EMC92425.1 - 1.2e-44 152.2 0.2 1.7e-44 151.7 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EMC92425.1 - 6.8e-10 38.4 8.0 5.4e-06 25.9 0.3 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC92425.1 - 3.1e-07 29.7 7.5 0.00082 19.1 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC92425.1 - 0.0001 21.7 10.8 0.0031 17.0 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC92425.1 - 0.00014 22.4 6.5 0.0014 19.2 1.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC92425.1 - 0.0028 17.5 4.2 0.019 14.8 0.5 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC92425.1 - 0.0076 16.6 1.2 0.17 12.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC92425.1 - 0.012 15.3 2.2 0.034 13.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC92425.1 - 0.017 15.6 2.6 0.46 11.2 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat RasGAP PF00616.14 EMC92427.1 - 1.8e-44 151.8 0.0 1.1e-42 145.9 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EMC92427.1 - 0.0036 17.1 0.1 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 C2 domain DUF1654 PF07867.6 EMC92427.1 - 0.05 12.9 0.0 8.7 5.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Abhydrolase_6 PF12697.2 EMC92428.1 - 5.3e-20 72.2 0.1 8.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC92428.1 - 3.5e-10 39.8 0.0 9.2e-10 38.4 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC92428.1 - 0.0019 17.8 0.1 0.0051 16.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC92428.1 - 0.045 12.9 0.1 5.4 6.1 0.2 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.9 EMC92428.1 - 0.047 12.1 0.1 0.079 11.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 EMC92428.1 - 0.074 12.9 0.1 0.27 11.1 0.1 1.9 1 1 0 1 1 1 0 Putative lysophospholipase Med1 PF10744.4 EMC92429.1 - 1.2e-32 113.1 0.0 2.9e-32 111.9 0.0 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 SpoIIIAH PF12685.2 EMC92430.1 - 0.1 12.0 4.1 0.16 11.4 2.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Macoilin PF09726.4 EMC92430.1 - 0.89 7.7 10.4 1.2 7.2 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 EMC92430.1 - 1.6 6.5 11.9 2.4 5.9 8.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Amidase PF01425.16 EMC92431.1 - 4.7e-88 295.9 0.0 5.6e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Amidoligase_2 PF12224.3 EMC92431.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme RRM_1 PF00076.17 EMC92433.1 - 2.5e-25 87.8 0.3 1.1e-13 50.6 0.1 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC92433.1 - 5e-23 80.8 0.0 4.8e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC92433.1 - 8.3e-06 25.5 0.3 0.0012 18.6 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC92433.1 - 0.00075 19.2 0.0 0.55 10.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Tom37_C PF11801.3 EMC92433.1 - 4.9 6.9 6.9 15 5.4 3.4 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain Ino80_Iec3 PF14612.1 EMC92434.1 - 2.5e-31 109.5 0.4 2.5e-31 109.5 0.3 2.4 2 1 0 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling SpaB_C PF14028.1 EMC92434.1 - 0.24 10.9 2.2 0.45 10.0 1.5 1.4 1 0 0 1 1 1 0 SpaB C-terminal domain IncA PF04156.9 EMC92434.1 - 0.66 9.5 7.4 1.4 8.4 5.1 1.5 1 0 0 1 1 1 0 IncA protein Glyco_tran_28_C PF04101.11 EMC92435.1 - 1.6e-19 70.1 0.2 8e-19 67.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EMC92435.1 - 0.0039 16.4 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 DUF3486 PF11985.3 EMC92435.1 - 0.054 13.5 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) MRP-S28 PF10213.4 EMC92436.1 - 2.2e-40 137.6 0.0 2.9e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein AIM24 PF01987.12 EMC92440.1 - 6.6e-50 169.5 0.3 8.2e-50 169.2 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Aldo_ket_red PF00248.16 EMC92441.1 - 4.8e-66 222.4 0.0 5.5e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family eIF-5_eIF-2B PF01873.12 EMC92442.1 - 4.2e-44 149.2 0.2 6.7e-44 148.5 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EMC92442.1 - 0.078 13.2 0.6 0.29 11.4 0.5 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 EMC92442.1 - 2 8.6 7.2 1.1 9.4 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain IFRD PF05004.8 EMC92445.1 - 3.5e-38 131.4 3.1 4.2e-38 131.1 2.2 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HCBP_related PF06594.6 EMC92445.1 - 0.23 11.1 1.7 8.1 6.1 0.1 3.1 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain WD40 PF00400.27 EMC92446.1 - 1.8e-60 198.7 25.0 1.1e-11 44.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMC92446.1 - 1.4e-05 23.4 6.3 0.23 9.5 0.2 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMC92446.1 - 0.022 13.0 0.1 3.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain PAN_4 PF14295.1 EMC92447.1 - 3.2e-13 49.1 10.8 1.5e-07 31.0 1.9 2.4 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.21 EMC92447.1 - 1.3e-06 28.0 3.6 0.0063 16.2 0.6 2.2 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.6 EMC92447.1 - 0.00083 19.1 5.6 0.037 13.8 0.8 2.6 2 0 0 2 2 2 2 PAN-like domain Toxin_5 PF05294.8 EMC92447.1 - 0.17 12.0 1.9 11 6.3 0.1 2.8 2 0 0 2 2 2 0 Scorpion short toxin PAN_3 PF08277.7 EMC92447.1 - 0.28 10.8 7.6 1.1 8.9 0.8 2.4 2 0 0 2 2 2 0 PAN-like domain Thionin PF00321.12 EMC92447.1 - 2.6 8.3 9.6 9.5 6.5 1.1 2.8 2 0 0 2 2 2 0 Plant thionin DUF4588 PF15251.1 EMC92448.1 - 1.1 9.1 12.6 7.4 6.4 8.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) CH PF00307.26 EMC92449.1 - 8.3e-09 35.4 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain ARGLU PF15346.1 EMC92449.1 - 0.0082 15.9 33.3 0.0082 15.9 23.1 3.2 3 0 0 3 3 3 1 Arginine and glutamate-rich 1 Snf7 PF03357.16 EMC92450.1 - 2.2e-28 98.7 19.0 2.2e-28 98.7 13.1 2.4 1 1 1 2 2 2 1 Snf7 CCDC84 PF14968.1 EMC92450.1 - 0.15 11.5 3.6 0.18 11.3 2.5 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Ten1 PF12658.2 EMC92451.1 - 2.2e-27 95.2 0.0 2.5e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EMC92451.1 - 0.037 13.5 0.0 0.057 12.9 0.0 1.6 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit DUF218 PF02698.12 EMC92452.1 - 5.5e-05 22.7 0.1 8e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 DUF218 domain Chitin_synth_1 PF01644.12 EMC92453.1 - 2.6e-65 219.1 0.0 3.8e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMC92453.1 - 5.7e-28 96.4 0.1 9.4e-28 95.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMC92453.1 - 1.8e-25 89.3 1.2 2.6e-21 75.6 0.0 2.2 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMC92453.1 - 3.3e-12 46.5 0.6 3.3e-12 46.5 0.4 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC92453.1 - 2.5e-08 34.0 0.0 7.4e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Adap_comp_sub PF00928.16 EMC92454.1 - 4.9e-52 176.6 0.0 1.2e-51 175.3 0.0 1.6 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMC92454.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Pyr_redox_3 PF13738.1 EMC92455.1 - 5.3e-18 65.8 0.0 1.1e-17 64.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC92455.1 - 6.2e-11 41.1 0.0 1.5e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMC92455.1 - 1.8e-10 40.7 0.0 6.1e-10 38.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMC92455.1 - 0.0002 20.4 0.0 0.0015 17.5 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) p450 PF00067.17 EMC92456.1 - 3.1e-40 138.0 0.0 4.6e-38 130.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Terpene_synth_C PF03936.11 EMC92457.1 - 3e-05 23.3 0.2 5.7e-05 22.4 0.2 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Aldedh PF00171.17 EMC92458.1 - 5e-74 249.2 0.0 6.1e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LINES_N PF14694.1 EMC92458.1 - 0.16 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Lines N-terminus RDM PF11002.3 EMC92458.1 - 0.2 11.3 3.0 7.8 6.2 0.0 3.3 3 0 0 3 3 3 0 RFPL defining motif (RDM) Trehalase PF01204.13 EMC92459.1 - 4.7e-185 616.0 0.5 5.8e-185 615.7 0.4 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EMC92459.1 - 4e-15 54.8 0.7 4e-15 54.8 0.5 1.8 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain Pkinase PF00069.20 EMC92460.1 - 4.7e-57 193.0 0.0 6e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92460.1 - 3.6e-33 114.7 0.0 5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC92460.1 - 3.2e-05 23.0 0.0 5.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC92460.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMC92460.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EMC92460.1 - 0.037 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase peroxidase PF00141.18 EMC92461.1 - 1.7e-85 286.2 0.0 5.2e-45 153.7 0.0 2.4 2 1 0 2 2 2 2 Peroxidase UPF0546 PF10639.4 EMC92462.1 - 2.2e-30 104.7 0.1 3.3e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 DUF4131 PF13567.1 EMC92462.1 - 0.18 11.2 5.0 1.8 7.9 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PhyH PF05721.8 EMC92463.1 - 1e-54 185.7 0.0 1.2e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Alpha-amylase PF00128.19 EMC92464.1 - 8e-63 212.7 1.6 1.1e-62 212.3 1.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EMC92464.1 - 8.7e-22 77.0 0.3 1.7e-21 76.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 EMC92464.1 - 0.0042 16.0 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme TPR_11 PF13414.1 EMC92467.1 - 1.2e-48 162.6 44.0 9.5e-13 47.5 1.1 6.8 4 2 4 8 8 8 8 TPR repeat TPR_1 PF00515.23 EMC92467.1 - 8.4e-39 129.6 30.2 0.00014 21.3 0.2 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMC92467.1 - 3.5e-34 113.9 29.1 0.0004 20.0 0.1 11.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 EMC92467.1 - 6.2e-25 87.2 17.4 0.00021 21.8 0.1 6.9 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMC92467.1 - 7e-23 80.3 27.9 1.5e-08 34.4 0.1 7.4 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EMC92467.1 - 6.2e-18 63.4 13.5 0.00016 21.5 0.0 8.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC92467.1 - 1.1e-14 52.9 17.6 0.054 13.3 0.1 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMC92467.1 - 3.4e-11 42.0 27.4 0.11 12.3 0.0 9.5 9 1 1 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMC92467.1 - 4.8e-10 39.6 21.2 5.8e-06 26.5 0.5 6.6 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC92467.1 - 7.6e-10 38.5 16.4 0.0037 17.0 0.2 6.4 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMC92467.1 - 8.3e-09 35.3 16.2 0.034 14.7 0.2 8.8 5 3 4 9 9 9 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC92467.1 - 1.2e-07 31.7 25.4 0.0016 18.5 0.4 5.6 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EMC92467.1 - 1.7e-07 30.9 10.2 0.1 12.5 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat MobA_MobL PF03389.10 EMC92467.1 - 0.028 13.8 0.2 0.077 12.3 0.1 1.7 1 0 0 1 1 1 0 MobA/MobL family TPR_6 PF13174.1 EMC92467.1 - 0.036 14.5 27.6 3.1 8.4 0.0 9.3 10 0 0 10 10 10 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMC92467.1 - 0.047 12.9 18.2 2.3 7.5 0.2 6.3 6 0 0 6 6 6 0 SHNi-TPR TPR_3 PF07720.7 EMC92467.1 - 0.054 13.3 18.1 2.5 7.9 0.2 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.7 EMC92467.1 - 1.7 9.3 7.7 1.4 9.6 0.1 4.1 3 0 0 3 3 3 0 Sel1 repeat ZZ PF00569.12 EMC92468.1 - 4.6e-20 70.8 50.5 7.2e-07 28.6 5.9 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Nop53 PF07767.6 EMC92468.1 - 1.1 8.2 18.6 2.3 7.1 12.9 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Btz PF09405.5 EMC92469.1 - 1.9e-21 76.4 5.5 1.9e-21 76.4 3.8 2.3 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding MFS_1 PF07690.11 EMC92470.1 - 3.8e-23 81.7 36.3 3.8e-23 81.7 25.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 EMC92470.1 - 0.00062 18.5 1.7 0.013 14.1 0.1 2.3 2 0 0 2 2 2 2 BT1 family C2 PF00168.25 EMC92472.1 - 6.6e-14 51.5 0.0 1.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Asp PF00026.18 EMC92474.1 - 1.2e-07 31.2 0.6 1.8e-07 30.6 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.8 EMC92474.1 - 7.1e-05 21.6 0.1 0.00012 20.8 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein TMEM51 PF15345.1 EMC92474.1 - 0.0013 18.4 1.0 0.0028 17.4 0.7 1.6 1 1 0 1 1 1 1 Transmembrane protein 51 Syndecan PF01034.15 EMC92474.1 - 0.0063 16.1 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 EMC92474.1 - 0.0091 15.2 1.2 0.02 14.2 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 EMC92474.1 - 0.022 13.9 0.1 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Neurensin PF14927.1 EMC92474.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Neurensin EphA2_TM PF14575.1 EMC92474.1 - 0.043 14.1 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EMC92474.1 - 0.067 11.9 0.2 0.21 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) P12 PF12669.2 EMC92474.1 - 0.076 13.2 0.2 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family IncA PF04156.9 EMC92474.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 IncA protein MtrF PF09472.5 EMC92474.1 - 1.1 8.6 3.4 2.2 7.5 2.3 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PUA PF01472.15 EMC92477.1 - 0.0016 18.1 0.3 0.83 9.4 0.0 2.6 1 1 2 3 3 3 2 PUA domain Aldolase PF01081.14 EMC92477.1 - 0.0081 15.3 3.0 0.011 14.9 2.1 1.2 1 0 0 1 1 1 1 KDPG and KHG aldolase SAF PF08666.7 EMC92477.1 - 0.064 13.6 0.1 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 SAF domain DUF3281 PF11685.3 EMC92477.1 - 0.23 10.5 7.3 0.55 9.3 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3281) A_amylase_inhib PF01356.14 EMC92477.1 - 0.24 11.2 5.4 1.7 8.4 0.3 2.5 1 1 1 2 2 2 0 Alpha amylase inhibitor D-aminoacyl_C PF07908.7 EMC92477.1 - 0.39 10.0 4.2 0.5 9.7 0.7 2.4 1 1 1 2 2 2 0 D-aminoacylase, C-terminal region Tail_tube PF10618.4 EMC92477.1 - 0.56 9.9 4.0 5.7 6.6 0.1 2.9 1 1 1 3 3 3 0 Phage tail tube protein FecR PF04773.8 EMC92477.1 - 0.97 9.7 6.3 42 4.4 4.4 2.5 1 1 0 1 1 1 0 FecR protein Cuticle_1 PF08140.6 EMC92477.1 - 4.9 7.0 8.1 12 5.7 0.6 2.5 2 0 0 2 2 2 0 Crustacean cuticle protein repeat EMP24_GP25L PF01105.19 EMC92478.1 - 1.6e-44 151.7 0.0 1.9e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Jnk-SapK_ap_N PF09744.4 EMC92478.1 - 0.073 13.0 0.2 0.11 12.5 0.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CorA PF01544.13 EMC92478.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein BTB PF00651.26 EMC92479.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain cNMP_binding PF00027.24 EMC92480.1 - 5.8e-42 141.4 0.0 3.8e-21 74.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EMC92480.1 - 2e-10 39.9 0.3 3.8e-10 39.0 0.2 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit GXGXG PF01493.14 EMC92480.1 - 0.028 13.4 0.0 0.57 9.1 0.0 2.1 2 0 0 2 2 2 0 GXGXG motif VitK2_biosynth PF02621.9 EMC92482.1 - 0.11 11.6 1.7 0.11 11.6 0.2 1.7 2 0 0 2 2 2 0 Menaquinone biosynthesis Sigma70_ner PF04546.8 EMC92482.1 - 0.11 12.1 0.3 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2984 PF11203.3 EMC92483.1 - 0.45 10.6 2.9 0.57 10.3 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) Aminotran_4 PF01063.14 EMC92484.1 - 1.2e-20 74.0 0.0 3e-20 72.6 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class IV Gln-synt_C PF00120.19 EMC92485.1 - 1.5e-62 211.1 0.0 1.7e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain TRP PF06011.7 EMC92486.1 - 9.1e-161 535.2 32.1 1.1e-160 535.0 22.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMC92486.1 - 3.6e-39 134.0 0.6 5.5e-39 133.4 0.4 1.3 1 0 0 1 1 1 1 ML-like domain 2OG-FeII_Oxy_2 PF13532.1 EMC92488.1 - 9.1e-25 87.6 0.0 1.4e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EMC92488.1 - 1.1e-24 87.2 0.0 1e-23 84.1 0.0 2.2 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy PF03171.15 EMC92488.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Hydantoinase_A PF01968.13 EMC92489.1 - 6.9e-80 268.2 1.9 6.9e-80 268.2 1.3 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EMC92489.1 - 3.9e-59 200.2 0.0 1.1e-58 198.8 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EMC92489.1 - 9.2e-47 158.7 0.0 7.1e-44 149.3 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EMC92489.1 - 2.1e-05 23.0 0.3 0.015 13.6 0.2 2.3 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EMC92489.1 - 0.027 13.7 0.6 0.35 10.1 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ppx-GppA PF02541.11 EMC92489.1 - 0.23 10.6 3.2 0.18 10.9 0.1 2.1 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Apolipoprotein PF01442.13 EMC92489.1 - 1.7 8.1 4.9 8.8 5.7 0.7 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Amidase PF01425.16 EMC92490.1 - 7.8e-86 288.6 2.6 1.4e-62 212.0 0.0 2.4 2 1 0 2 2 2 2 Amidase COesterase PF00135.23 EMC92491.1 - 7e-38 130.6 0.9 1.1e-37 129.9 0.6 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC92491.1 - 0.00014 21.5 0.1 0.077 12.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sugar_tr PF00083.19 EMC92492.1 - 3.7e-72 243.3 26.8 4.5e-72 243.0 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC92492.1 - 2.8e-20 72.3 29.4 2.8e-20 72.3 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EMC92493.1 - 2.6e-10 39.6 0.6 3.9e-10 39.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 EMC92494.1 - 3.2e-43 148.2 0.0 4.4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EMC92494.1 - 4.3e-07 30.2 0.1 1.2e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Ribosomal_L13e PF01294.13 EMC92494.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e Plus-3 PF03126.13 EMC92495.1 - 1.2e-33 115.3 0.0 2.7e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.8 EMC92496.1 - 2e-62 209.6 0.1 2.4e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EMC92496.1 - 0.0012 19.2 0.2 0.0021 18.4 0.1 1.6 1 1 0 1 1 1 1 Rubrerythrin GlutR_dimer PF00745.15 EMC92496.1 - 0.077 12.9 0.2 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain UPF0184 PF03670.8 EMC92496.1 - 0.19 11.9 1.1 0.35 11.0 0.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) AAA_12 PF13087.1 EMC92499.1 - 1.5e-33 115.8 0.0 2.3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMC92499.1 - 1.9e-18 66.9 0.1 5.9e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EMC92499.1 - 1.3e-09 37.6 0.0 1.2e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMC92499.1 - 6.2e-08 32.4 0.0 6.2e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EMC92499.1 - 3.9e-05 23.2 0.0 0.22 11.0 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EMC92499.1 - 0.00032 20.1 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EMC92499.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C PF13361.1 EMC92499.1 - 0.0012 18.4 0.0 0.53 9.6 0.0 2.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 EMC92499.1 - 0.0023 17.6 0.0 0.007 16.0 0.0 1.8 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 EMC92499.1 - 0.0041 17.2 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC92499.1 - 0.0089 16.0 0.1 0.039 13.9 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain PhoH PF02562.11 EMC92499.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EMC92499.1 - 0.015 14.3 0.0 0.064 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EMC92499.1 - 0.018 15.2 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EMC92499.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_17 PF13207.1 EMC92499.1 - 0.067 14.0 0.0 0.26 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain IlvN PF07991.7 EMC92500.1 - 1.8e-46 157.5 0.0 2.7e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EMC92500.1 - 1.1e-44 151.8 0.1 1.7e-44 151.2 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EMC92500.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMC92500.1 - 0.042 14.2 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CotJA PF11007.3 EMC92500.1 - 0.085 12.5 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) PLDc PF00614.17 EMC92501.1 - 1.3e-14 53.4 1.0 4.6e-07 29.4 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EMC92501.1 - 3.2e-12 46.3 0.0 5.2e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EMC92501.1 - 1.5e-07 31.1 0.0 8.3e-07 28.7 0.0 2.3 2 1 0 2 2 2 1 PX domain Abhydrolase_6 PF12697.2 EMC92502.1 - 7.9e-11 42.2 0.2 1.2e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC92502.1 - 2.8e-10 40.1 0.0 1.9e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PRELI PF04707.9 EMC92503.1 - 7.9e-21 74.2 0.0 1e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 PRELI-like family tRNA-synt_1b PF00579.20 EMC92504.1 - 1e-19 70.7 0.0 1.4e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) SNF2_N PF00176.18 EMC92505.1 - 1.2e-81 273.8 0.1 2e-81 273.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EMC92505.1 - 1.9e-42 143.7 2.9 4e-42 142.6 0.3 2.8 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EMC92505.1 - 1.1e-28 99.9 0.2 1.1e-28 99.9 0.2 3.2 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EMC92505.1 - 1.5e-14 53.6 0.0 6e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC92505.1 - 2.9e-09 37.0 0.0 1.4e-08 34.7 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC92505.1 - 2.6e-06 27.0 0.0 7.5e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Isochorismatase PF00857.15 EMC92505.1 - 0.018 14.9 2.4 2.4 8.0 0.0 2.9 3 0 0 3 3 3 0 Isochorismatase family AAA_14 PF13173.1 EMC92505.1 - 0.019 14.8 0.1 0.098 12.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.10 EMC92505.1 - 0.023 14.1 0.2 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_22 PF13401.1 EMC92505.1 - 0.027 14.5 0.6 0.25 11.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain NAD_binding_6 PF08030.7 EMC92507.1 - 4.1e-16 59.2 0.0 6.2e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMC92507.1 - 1.4e-14 54.2 8.9 1.4e-14 54.2 6.2 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMC92507.1 - 2.5e-11 43.3 0.0 1.5e-10 40.8 0.0 2.2 2 1 1 3 3 3 1 FAD-binding domain DUF3455 PF11937.3 EMC92508.1 - 1.8e-30 106.1 0.1 2.3e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) RF-1 PF00472.15 EMC92513.1 - 1.3e-32 111.9 6.1 2.3e-32 111.1 3.2 2.1 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EMC92513.1 - 7e-27 93.4 0.0 4.4e-26 90.8 0.0 2.2 2 1 0 2 2 2 1 PCRF domain MscS_porin PF12795.2 EMC92513.1 - 0.22 10.8 10.8 0.12 11.6 1.3 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TarH PF02203.10 EMC92513.1 - 0.23 11.3 3.1 1.2 8.9 0.4 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue OmpH PF03938.9 EMC92513.1 - 1 9.2 6.9 13 5.6 4.8 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Nuc_N PF14448.1 EMC92514.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Nuclease N terminal Transthyretin PF00576.16 EMC92515.1 - 1.9e-26 92.1 0.1 5.7e-25 87.3 0.1 2.0 1 1 0 1 1 1 1 HIUase/Transthyretin family B9-C2 PF07162.6 EMC92515.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein adh_short_C2 PF13561.1 EMC92516.1 - 3.4e-29 102.3 0.0 4.2e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC92516.1 - 6.6e-20 71.6 0.1 9.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 EMC92516.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 EMC92516.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Methyltransf_26 PF13659.1 EMC92516.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_deac_1 PF01522.16 EMC92517.1 - 7.7e-26 90.1 0.0 1.1e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 EMC92517.1 - 0.0008 18.4 0.0 0.005 15.8 0.0 2.0 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase HTH_39 PF14090.1 EMC92517.1 - 0.086 12.3 0.3 0.62 9.5 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain Ribonuc_2-5A PF06479.7 EMC92517.1 - 0.15 11.9 0.1 0.51 10.1 0.1 1.9 2 1 0 2 2 2 0 Ribonuclease 2-5A Peptidase_M20 PF01546.23 EMC92518.1 - 2.9e-30 105.1 0.0 5.2e-30 104.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMC92518.1 - 8.8e-15 54.4 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Fork_head PF00250.13 EMC92520.1 - 8e-13 48.2 0.1 9.3e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 Fork head domain Pkinase PF00069.20 EMC92524.1 - 5.9e-75 251.7 0.0 1e-74 251.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92524.1 - 1.3e-38 132.5 0.0 1.9e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EMC92524.1 - 7.6e-16 58.0 0.1 1.6e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EMC92524.1 - 7.7e-07 28.3 0.0 2e-06 26.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EMC92524.1 - 0.00015 21.1 0.4 0.00077 18.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family YukC PF10140.4 EMC92524.1 - 0.016 13.7 0.0 0.024 13.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EMC92524.1 - 0.031 13.3 0.1 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MARVEL PF01284.18 EMC92525.1 - 1.2e-20 73.8 10.0 1.4e-20 73.6 6.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain Fig1 PF12351.3 EMC92525.1 - 0.018 14.9 3.1 0.028 14.2 2.1 1.3 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Ni_hydr_CYTB PF01292.15 EMC92525.1 - 0.059 12.7 1.5 0.14 11.5 1.0 1.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Tic20 PF09685.5 EMC92525.1 - 0.75 9.8 6.2 0.33 10.9 2.5 1.8 2 0 0 2 2 2 0 Tic20-like protein Glyco_transf_28 PF03033.15 EMC92526.1 - 2.8e-18 66.0 0.0 1.8e-17 63.3 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMC92526.1 - 1.1e-05 24.2 0.0 1.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMC92526.1 - 0.00028 20.5 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SKG6 PF08693.5 EMC92530.1 - 9.2e-05 21.6 0.3 0.00036 19.7 0.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EMC92530.1 - 0.026 14.0 5.3 0.04 13.4 3.6 1.4 1 0 0 1 1 1 0 Podoplanin DUF4462 PF14692.1 EMC92530.1 - 0.065 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Trs65 PF12735.2 EMC92530.1 - 1.8 7.7 9.1 2.4 7.3 6.3 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 PhyH PF05721.8 EMC92531.1 - 1.9e-16 60.7 0.0 2.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EMC92531.1 - 0.081 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.19 EMC92532.1 - 3.2e-69 233.6 22.7 3.6e-69 233.4 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC92532.1 - 1.7e-12 46.7 26.7 1.7e-12 46.7 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tyr_Deacylase PF02580.11 EMC92533.1 - 4e-46 156.5 0.1 5.2e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 EMC92534.1 - 4.9e-95 317.2 29.5 7.1e-95 316.7 20.5 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EMC92534.1 - 1.3e-41 141.6 9.2 1.3e-41 141.6 6.4 2.2 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family CorA PF01544.13 EMC92534.1 - 0.0077 15.3 3.5 0.0077 15.3 2.4 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2373 PF10180.4 EMC92534.1 - 0.02 14.4 1.7 0.047 13.2 1.2 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 EMC92534.1 - 0.066 13.0 4.5 0.065 13.0 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cep57_MT_bd PF06657.8 EMC92534.1 - 1.6 8.7 11.6 0.65 9.9 0.7 3.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MFS_1 PF07690.11 EMC92535.1 - 1.4e-18 66.7 39.5 1.4e-18 66.7 27.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 EMC92536.1 - 9.8e-22 76.7 0.7 2.1e-21 75.7 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC92536.1 - 4.4e-13 48.8 0.1 8.6e-13 47.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMC92536.1 - 7.6e-05 21.9 0.1 0.00015 21.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMC92536.1 - 0.019 14.5 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMC92536.1 - 0.074 12.6 0.1 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMC92536.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EMC92536.1 - 0.23 11.2 0.7 0.44 10.3 0.5 1.4 1 0 0 1 1 1 0 ThiF family SAP PF02037.22 EMC92539.1 - 0.00084 18.7 0.1 0.0019 17.6 0.1 1.6 1 0 0 1 1 1 1 SAP domain Endonuc_BglI PF14562.1 EMC92539.1 - 0.015 14.1 0.1 0.026 13.3 0.0 1.3 1 1 0 1 1 1 0 Restriction endonuclease BglI WSK PF03832.8 EMC92539.1 - 0.13 11.6 0.2 0.13 11.6 0.1 2.9 3 0 0 3 3 3 0 WSK motif LTXXQ PF07813.7 EMC92540.1 - 0.026 14.9 0.9 0.031 14.7 0.7 1.2 1 0 0 1 1 1 0 LTXXQ motif family protein Metallophos_3 PF14582.1 EMC92540.1 - 0.086 11.9 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF3886 PF13025.1 EMC92540.1 - 1.6 8.7 4.5 3.9 7.5 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) ECR1_N PF14382.1 EMC92542.1 - 7e-08 31.6 0.0 2.2e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Apolipoprotein PF01442.13 EMC92544.1 - 0.0034 16.9 1.6 0.005 16.3 1.1 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain V-ATPase_G PF03179.10 EMC92544.1 - 0.0097 16.1 4.8 0.014 15.6 3.3 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PIN_2 PF10130.4 EMC92544.1 - 0.01 15.8 1.5 0.013 15.5 1.1 1.1 1 0 0 1 1 1 0 PIN domain DUF1548 PF07579.6 EMC92544.1 - 0.08 13.0 0.2 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) 4HB_MCP_1 PF12729.2 EMC92544.1 - 0.12 11.7 3.5 0.17 11.2 2.4 1.3 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction TMCO5 PF14992.1 EMC92544.1 - 0.19 10.8 4.1 0.22 10.6 2.9 1.1 1 0 0 1 1 1 0 TMCO5 family HCV_NS4a PF01006.15 EMC92544.1 - 0.19 11.2 0.6 0.32 10.5 0.4 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DUF883 PF05957.8 EMC92544.1 - 0.24 11.8 6.7 0.31 11.4 3.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Pilin PF00114.14 EMC92544.1 - 0.37 11.5 5.2 1.8 9.3 3.6 2.0 1 1 0 1 1 1 0 Pilin (bacterial filament) HrpF PF06266.7 EMC92544.1 - 0.41 10.8 3.2 0.89 9.7 1.1 2.3 1 1 1 2 2 2 0 HrpF protein ATP-synt_B PF00430.13 EMC92544.1 - 0.58 9.9 8.6 0.41 10.4 4.2 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2317 PF10079.4 EMC92544.1 - 0.7 8.4 3.7 0.85 8.1 2.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) RRF PF01765.14 EMC92544.1 - 0.86 9.0 6.9 1.5 8.3 4.8 1.4 1 1 0 1 1 1 0 Ribosome recycling factor Phasin PF05597.6 EMC92544.1 - 2.1 8.1 7.4 4.8 6.9 2.4 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4094 PF13334.1 EMC92545.1 - 0.25 11.7 2.7 1.2 9.6 1.8 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TRAP_alpha PF03896.11 EMC92546.1 - 3 6.7 8.8 7.9 5.3 6.1 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ZZ PF00569.12 EMC92548.1 - 1.6e-05 24.3 5.7 2.9e-05 23.5 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-ribbon_3 PF13248.1 EMC92548.1 - 5.4 6.3 8.2 10 5.4 5.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain SH3_1 PF00018.23 EMC92549.1 - 3.6e-15 55.0 0.0 5.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC92549.1 - 4.8e-12 45.2 0.0 8e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC92549.1 - 6e-09 35.2 0.0 1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Iso_dh PF00180.15 EMC92550.1 - 4.4e-75 252.7 0.0 5.1e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3253 PF11625.3 EMC92551.1 - 7.9e-09 35.2 0.0 9e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) AMP-binding PF00501.23 EMC92553.1 - 3.3e-07 29.0 0.0 3.6e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Oxysterol_BP PF01237.13 EMC92555.1 - 3.6e-70 236.2 0.0 6.1e-70 235.4 0.0 1.2 1 1 0 1 1 1 1 Oxysterol-binding protein ECH PF00378.15 EMC92556.1 - 7.5e-38 130.0 0.0 1e-36 126.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2029 PF09594.5 EMC92557.1 - 0.0064 16.0 1.1 0.009 15.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) PepSY_TM_2 PF13703.1 EMC92557.1 - 0.018 15.1 0.6 0.018 15.1 0.4 2.6 2 1 1 3 3 3 0 PepSY-associated TM helix GAPT PF11770.3 EMC92557.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) RNase_T PF00929.19 EMC92560.1 - 1.4e-26 93.7 0.0 1.6e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Sec63 PF02889.11 EMC92561.1 - 3.2e-153 509.4 0.0 6.1e-96 321.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EMC92561.1 - 9.9e-56 187.8 0.5 7.7e-29 100.3 0.5 4.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC92561.1 - 4.1e-17 61.8 0.0 2.2e-07 30.6 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMC92561.1 - 1.1e-16 61.2 0.0 4.5e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMC92561.1 - 2e-10 40.9 0.1 0.00065 19.8 0.0 3.5 2 0 0 2 2 2 2 AAA domain SNF2_N PF00176.18 EMC92561.1 - 1.4e-06 27.3 0.3 0.042 12.6 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_19 PF13245.1 EMC92561.1 - 1.9e-05 24.3 0.1 0.078 12.7 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EMC92561.1 - 0.0051 16.2 0.3 13 5.2 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein PhoH PF02562.11 EMC92561.1 - 0.023 13.9 0.0 3.1 6.9 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 EMC92561.1 - 0.026 14.0 0.0 4.3 6.7 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Alba PF01918.16 EMC92561.1 - 0.062 12.9 0.0 0.61 9.7 0.0 2.7 2 0 0 2 2 2 0 Alba Actin PF00022.14 EMC92562.1 - 1.6e-50 171.7 0.0 1.5e-29 102.6 0.0 2.2 2 0 0 2 2 2 2 Actin DUF3040 PF11239.3 EMC92562.1 - 0.54 10.3 2.5 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) 3HCDH_N PF02737.13 EMC92563.1 - 8e-51 172.2 0.2 1.4e-50 171.4 0.1 1.4 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMC92563.1 - 7.7e-31 106.3 0.0 1.4e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 EMC92563.1 - 0.0022 17.1 0.0 0.004 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMC92563.1 - 0.0078 16.0 0.2 0.015 15.1 0.2 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EMC92563.1 - 0.012 14.5 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EMC92563.1 - 0.023 14.3 0.1 0.053 13.2 0.1 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 EMC92563.1 - 0.067 12.0 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC92563.1 - 0.078 13.0 0.9 0.27 11.2 0.4 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMC92563.1 - 0.084 12.8 0.7 0.23 11.4 0.0 2.1 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_3 PF01494.14 EMC92565.1 - 1.4e-07 30.9 0.3 6e-07 28.8 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EMC92565.1 - 0.015 14.1 0.0 0.067 12.0 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.1 EMC92565.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-Sec23_Sec24 PF04810.10 EMC92565.1 - 0.11 12.0 0.2 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Lactamase_B PF00753.22 EMC92568.1 - 4.3e-09 36.2 4.4 1.8e-08 34.2 3.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC92568.1 - 0.0032 17.0 0.1 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain YL1_C PF08265.6 EMC92569.1 - 4.3e-15 54.9 0.8 8e-15 54.1 0.5 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ribosomal_S9 PF00380.14 EMC92570.1 - 9.8e-40 135.5 0.3 1.1e-39 135.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SMC_Nse1 PF07574.8 EMC92571.1 - 4.3e-37 127.6 0.0 5.8e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EMC92571.1 - 1.3e-10 41.0 9.3 2.2e-10 40.3 6.4 1.4 1 0 0 1 1 1 1 RING-like domain zf-Apc11 PF12861.2 EMC92571.1 - 0.00014 21.5 1.2 0.00024 20.8 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EMC92571.1 - 0.00027 20.7 6.7 0.00048 19.9 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.17 EMC92571.1 - 0.0044 16.7 1.0 0.0044 16.7 0.7 1.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Spore_YpjB PF09577.5 EMC92571.1 - 0.099 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) zf-RING_5 PF14634.1 EMC92571.1 - 1 9.1 6.7 2.2 8.0 4.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC92571.1 - 1.3 8.7 4.7 3.3 7.4 3.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC92571.1 - 1.9 8.5 5.5 2.7 8.0 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC92571.1 - 9.2 6.0 8.1 1.8e+02 1.8 5.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TIMELESS PF04821.9 EMC92572.1 - 6.6e-86 287.8 0.8 1.3e-85 286.8 0.6 1.5 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 EMC92572.1 - 1.3e-15 57.4 0.0 1.3e-15 57.4 0.0 4.6 2 1 1 3 3 3 1 Timeless protein C terminal region F-box PF00646.28 EMC92573.1 - 0.024 14.2 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 F-box domain DUF3659 PF12396.3 EMC92573.1 - 0.059 13.0 0.1 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3659) F-box-like PF12937.2 EMC92573.1 - 0.12 12.1 0.1 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like K_oxygenase PF13434.1 EMC92574.1 - 3.3e-104 348.4 0.0 4e-104 348.2 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMC92574.1 - 4.8e-09 36.1 0.0 1.1e-06 28.5 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMC92574.1 - 5e-08 33.2 0.0 1e-07 32.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC92574.1 - 8.9e-05 22.4 0.0 0.001 18.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 EMC92574.1 - 0.018 14.1 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) ABC_membrane PF00664.18 EMC92576.1 - 3.8e-69 233.1 22.7 8.4e-35 120.5 3.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC92576.1 - 4.1e-61 205.2 0.0 2e-31 109.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMC92576.1 - 8.2e-11 42.3 0.0 0.042 13.8 0.0 4.2 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EMC92576.1 - 3.5e-10 39.4 5.2 0.00059 19.1 0.2 4.0 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EMC92576.1 - 1e-06 27.6 2.7 0.0046 15.5 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EMC92576.1 - 2.8e-05 23.3 0.0 0.15 11.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC92576.1 - 4.7e-05 24.1 0.0 0.62 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EMC92576.1 - 0.00016 21.3 0.0 0.034 13.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC92576.1 - 0.00086 18.4 0.0 0.15 11.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 EMC92576.1 - 0.002 17.5 3.7 0.58 9.7 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EMC92576.1 - 0.0022 17.4 3.9 0.36 10.2 0.5 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMC92576.1 - 0.0022 17.8 0.0 0.82 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMC92576.1 - 0.0028 17.1 0.5 5.8 6.2 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_23 PF13476.1 EMC92576.1 - 0.016 15.5 0.1 3 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain UcrQ PF02939.11 EMC92576.1 - 0.071 12.9 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 UcrQ family AAA_22 PF13401.1 EMC92576.1 - 0.08 13.0 2.0 2.7 8.1 0.1 3.6 2 2 0 2 2 2 0 AAA domain DUF1673 PF07895.6 EMC92576.1 - 2.9 7.3 5.9 1.4 8.3 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1673) AMP-binding PF00501.23 EMC92577.1 - 2.9e-249 826.3 0.0 6.9e-92 307.9 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EMC92577.1 - 1.4e-184 611.8 0.0 1.4e-35 122.6 0.0 8.0 6 2 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EMC92577.1 - 2.7e-54 181.3 7.1 3.1e-09 36.9 0.1 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site wnt PF00110.14 EMC92577.1 - 5.7 6.0 0.0 10 5.1 0.0 1.3 1 0 0 1 1 1 0 wnt family AATase PF07247.7 EMC92577.1 - 5.7 5.3 0.2 85 1.5 0.0 2.5 3 0 0 3 3 3 0 Alcohol acetyltransferase DUF787 PF05619.6 EMC92577.1 - 8.2 4.9 0.0 15 4.1 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) PGM_PMM_I PF02878.11 EMC92579.1 - 1.6e-15 56.7 0.0 3.6e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMC92579.1 - 2.9e-15 56.4 0.3 4e-13 49.5 0.1 2.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMC92579.1 - 1.1e-07 31.6 0.1 6.8e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EMC92579.1 - 0.0011 18.9 0.1 0.0024 17.9 0.1 1.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III AAA PF00004.24 EMC92580.1 - 2.4e-59 199.2 0.0 2.5e-41 140.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC92580.1 - 6.6e-10 39.2 3.4 6.1e-05 23.0 2.0 4.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EMC92580.1 - 2.2e-07 31.0 2.8 0.0089 16.1 0.0 4.2 3 2 2 5 5 5 2 AAA domain DUF815 PF05673.8 EMC92580.1 - 4.5e-06 25.7 0.0 0.0076 15.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_5 PF07728.9 EMC92580.1 - 1e-05 25.3 0.1 0.0047 16.6 0.0 3.3 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMC92580.1 - 0.00013 21.9 0.0 0.00044 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EMC92580.1 - 0.00014 21.3 0.0 0.013 14.9 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EMC92580.1 - 0.00016 20.8 0.0 0.16 11.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EMC92580.1 - 0.00026 20.0 0.1 0.063 12.3 0.0 3.1 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMC92580.1 - 0.00082 19.2 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC92580.1 - 0.0012 18.3 1.2 1.5 8.2 0.0 3.8 2 2 2 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.1 EMC92580.1 - 0.0013 18.7 0.0 0.072 13.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 EMC92580.1 - 0.0023 17.6 0.7 5 6.7 0.0 4.0 3 1 0 4 4 4 1 NACHT domain TIP49 PF06068.8 EMC92580.1 - 0.0033 16.2 0.0 0.014 14.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus DAP3 PF10236.4 EMC92580.1 - 0.005 15.8 0.0 0.036 13.0 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.17 EMC92580.1 - 0.0084 16.2 0.0 5.3 7.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 EMC92580.1 - 0.016 14.9 0.6 5.1 6.7 0.0 3.5 2 2 2 4 4 4 0 Archaeal ATPase AAA_17 PF13207.1 EMC92580.1 - 0.016 16.0 0.1 0.81 10.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMC92580.1 - 0.016 15.5 0.1 1.4 9.1 0.0 3.0 3 1 0 3 3 2 0 ABC transporter Zeta_toxin PF06414.7 EMC92580.1 - 0.019 14.0 0.0 6.4 5.8 0.0 2.9 3 1 0 3 3 3 0 Zeta toxin CDC48_N PF02359.13 EMC92580.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.6 EMC92580.1 - 0.025 14.1 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EMC92580.1 - 0.059 12.8 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EMC92580.1 - 0.076 12.4 0.1 6.2 6.1 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.1 EMC92580.1 - 0.11 12.4 0.9 19 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Arm PF00514.18 EMC92582.1 - 0.022 14.5 0.3 0.17 11.7 0.1 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DPM3 PF08285.6 EMC92583.1 - 6e-36 122.1 0.1 6.6e-36 122.0 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1624 PF07786.7 EMC92583.1 - 0.098 11.9 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) DUF1349 PF07081.6 EMC92585.1 - 1.8e-28 99.1 0.0 2.2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Brr6_like_C_C PF10104.4 EMC92586.1 - 8.4e-45 151.5 4.1 1.1e-44 151.2 2.9 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Dynamin_N PF00350.18 EMC92587.1 - 4.8e-25 88.3 0.6 2.8e-24 85.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EMC92587.1 - 9.5e-15 54.1 0.0 3.4e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EMC92587.1 - 3.1e-06 27.0 2.9 4.6e-06 26.4 0.6 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMC92587.1 - 0.0024 17.8 0.2 0.032 14.1 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase VASP_tetra PF08776.6 EMC92587.1 - 0.003 16.8 0.8 0.0067 15.7 0.6 1.6 1 0 0 1 1 1 1 VASP tetramerisation domain Miro PF08477.8 EMC92587.1 - 0.042 14.3 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein DUF1096 PF06493.6 EMC92588.1 - 9.9 6.2 41.4 87 3.1 14.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) Adaptin_N PF01602.15 EMC92589.1 - 2.2e-123 412.3 10.0 2.7e-123 412.0 6.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EMC92589.1 - 3e-40 136.7 0.0 6.7e-40 135.5 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EMC92589.1 - 1.3e-19 70.5 0.1 2.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EMC92589.1 - 0.00015 22.0 0.9 0.3 11.3 0.0 4.8 4 2 1 5 5 5 1 HEAT repeats TFIIB PF00382.14 EMC92590.1 - 1.1e-30 105.2 2.9 1.6e-18 66.2 0.1 3.2 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EMC92590.1 - 3.6e-16 59.1 4.7 3.6e-16 59.1 3.2 3.7 3 0 0 3 3 3 2 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EMC92590.1 - 0.00098 18.6 0.0 0.027 14.0 0.0 2.4 1 1 1 2 2 2 1 Cyclin, N-terminal domain DUF664 PF04978.7 EMC92590.1 - 0.38 10.9 5.5 1.7 8.8 3.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF664) BTB PF00651.26 EMC92591.1 - 2.1e-05 24.4 0.0 0.0007 19.5 0.0 2.1 1 1 1 2 2 2 2 BTB/POZ domain PHD PF00628.24 EMC92592.1 - 8.6e-11 41.3 7.4 1.3e-10 40.7 5.1 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EMC92592.1 - 0.00012 21.7 2.2 0.00012 21.7 1.5 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EMC92592.1 - 0.0015 17.8 7.9 0.0088 15.3 5.5 2.2 1 1 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EMC92592.1 - 0.0058 15.9 3.7 0.015 14.6 2.6 1.6 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EMC92592.1 - 0.0093 15.6 3.1 0.034 13.8 0.5 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 EMC92592.1 - 0.043 13.7 1.0 0.07 13.0 0.7 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.2 EMC92592.1 - 2.1 8.2 7.5 4.4 7.1 1.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon API5 PF05918.6 EMC92592.1 - 5.3 5.4 4.3 7.1 5.0 3.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) BTB PF00651.26 EMC92593.1 - 0.0043 17.0 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-BED PF02892.10 EMC92595.1 - 0.0022 17.6 0.1 0.005 16.5 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_jaz PF12171.3 EMC92595.1 - 0.11 12.6 2.6 6 7.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMC92595.1 - 0.54 10.7 8.1 0.73 10.2 0.2 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type AP3B1_C PF14796.1 EMC92598.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal GFA PF04828.9 EMC92598.1 - 0.15 11.9 2.6 0.13 12.1 0.9 1.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Lum_binding PF00677.12 EMC92603.1 - 1.1e-41 140.6 1.6 4.2e-23 81.0 0.1 2.2 2 0 0 2 2 2 2 Lumazine binding domain CoA_transf_3 PF02515.12 EMC92604.1 - 2.1e-58 196.7 0.3 4.6e-58 195.6 0.1 1.6 2 0 0 2 2 2 1 CoA-transferase family III Bud13 PF09736.4 EMC92605.1 - 4.5e-44 150.2 11.0 4.5e-44 150.2 7.7 2.7 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DNA_binding_1 PF01035.15 EMC92606.1 - 2.3e-21 75.3 0.3 4.2e-21 74.4 0.2 1.4 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain F-box PF00646.28 EMC92607.1 - 1.3e-05 24.7 0.2 4e-05 23.1 0.1 1.8 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.2 EMC92607.1 - 0.0017 18.0 3.9 0.0034 17.0 0.2 2.6 3 0 0 3 3 3 1 F-box-like AMP-binding PF00501.23 EMC92608.1 - 2.3e-78 263.4 0.0 3.1e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC92608.1 - 3.7e-12 46.9 0.2 1.2e-11 45.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EMC92609.1 - 1.7e-05 24.8 0.2 2.1e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC92609.1 - 0.013 15.1 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 EMC92609.1 - 0.071 12.9 0.2 0.085 12.6 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_3 PF07859.8 EMC92610.1 - 6.4e-37 127.1 0.4 1.6e-27 96.4 0.3 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EMC92610.1 - 4.5e-14 51.8 0.0 6.7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EMC92610.1 - 0.0014 17.3 0.2 0.54 8.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family SpoIIIAH PF12685.2 EMC92610.1 - 0.052 13.0 0.2 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 SpoIIIAH-like protein Abhydrolase_3 PF07859.8 EMC92611.1 - 5.4e-47 160.1 0.0 1.6e-46 158.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMC92611.1 - 7.3e-09 34.8 0.3 1.5e-08 33.8 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMC92611.1 - 0.00082 19.1 0.0 0.0012 18.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC92611.1 - 0.02 14.3 0.1 0.051 13.0 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EMC92611.1 - 0.13 11.0 0.0 0.29 10.0 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EMC92611.1 - 0.14 11.3 0.4 0.37 9.9 0.0 1.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF1772 PF08592.6 EMC92612.1 - 1.6e-08 34.3 0.2 1.7e-08 34.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) COX2-transmemb PF09125.5 EMC92612.1 - 0.098 12.2 0.5 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane RRM_1 PF00076.17 EMC92613.1 - 4.3e-09 35.8 0.0 8.3e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC92613.1 - 1.4e-07 31.3 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC92613.1 - 7e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMC92613.1 - 0.039 13.8 0.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.1 EMC92613.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-AN1 PF01428.11 EMC92615.1 - 0.01 15.6 0.5 0.01 15.6 0.3 1.7 2 0 0 2 2 2 0 AN1-like Zinc finger Kinetocho_Slk19 PF12709.2 EMC92616.1 - 6.9e-15 54.8 3.3 6.9e-15 54.8 2.3 4.0 4 0 0 4 4 4 2 Central kinetochore-associated FlaC_arch PF05377.6 EMC92616.1 - 0.13 12.1 10.9 10 6.1 0.1 4.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 EMC92616.1 - 0.15 11.2 3.9 2.8 7.0 1.1 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein UPF0254 PF06787.6 EMC92616.1 - 0.32 10.5 3.3 0.88 9.0 0.4 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0254) TMF_DNA_bd PF12329.3 EMC92616.1 - 4.3 7.2 37.6 0.027 14.2 2.1 4.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DbpA PF03880.10 EMC92617.1 - 0.0084 15.7 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain PKD_channel PF08016.7 EMC92617.1 - 0.025 12.9 0.2 0.038 12.4 0.1 1.1 1 0 0 1 1 1 0 Polycystin cation channel Herpes_LMP2 PF07415.6 EMC92617.1 - 0.1 11.1 0.1 0.23 10.0 0.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF418 PF04235.7 EMC92617.1 - 0.2 11.3 3.6 0.32 10.6 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) CoA_binding_3 PF13727.1 EMC92617.1 - 0.4 10.4 2.7 0.53 10.0 1.1 1.7 2 0 0 2 2 2 0 CoA-binding domain ABC2_membrane_2 PF12679.2 EMC92617.1 - 2.5 6.8 7.6 3.6 6.3 5.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ATP-grasp_2 PF08442.5 EMC92620.1 - 1.5e-76 256.2 1.8 1.5e-76 256.2 1.2 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EMC92620.1 - 2.5e-26 92.0 0.4 6.8e-26 90.7 0.3 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EMC92620.1 - 5.4e-09 35.6 0.4 1.3e-08 34.3 0.3 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EMC92620.1 - 0.00026 20.6 1.1 0.019 14.4 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EMC92620.1 - 0.0021 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EMC92620.1 - 0.0028 17.1 0.2 0.047 13.1 0.0 2.7 3 0 0 3 3 3 1 RimK-like ATP-grasp domain adh_short PF00106.20 EMC92621.1 - 4.3e-32 111.3 2.2 5.3e-32 111.0 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92621.1 - 4.3e-15 56.1 0.0 5.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92621.1 - 1.6e-13 50.7 2.2 2e-13 50.3 1.6 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC92621.1 - 5e-07 29.8 0.5 8.6e-07 29.1 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC92621.1 - 0.0025 17.2 0.2 0.0091 15.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC92621.1 - 0.0048 15.8 0.0 0.0072 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EMC92621.1 - 0.031 14.2 0.0 0.068 13.1 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain DUF2749 PF10907.3 EMC92621.1 - 0.12 12.2 0.1 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DAO PF01266.19 EMC92622.1 - 2.1e-34 119.0 2.6 3e-34 118.5 1.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC92622.1 - 4.9e-06 26.8 0.0 0.0065 16.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC92622.1 - 0.0001 22.2 0.1 0.00068 19.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC92622.1 - 0.021 14.7 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EMC92622.1 - 0.04 12.2 0.0 0.056 11.7 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 EMC92622.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.11 EMC92622.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EMC92622.1 - 0.074 11.6 0.1 0.33 9.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 EMC92622.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family LuxS PF02664.10 EMC92622.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) SDA1 PF05285.7 EMC92625.1 - 1 8.6 16.2 1.2 8.2 11.2 1.1 1 0 0 1 1 1 0 SDA1 TPR_11 PF13414.1 EMC92626.1 - 7.6e-17 60.7 7.4 7.8e-10 38.2 0.1 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EMC92626.1 - 1.9e-13 49.3 5.3 1.6e-06 27.4 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC92626.1 - 6.7e-13 47.4 3.4 0.00016 21.3 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 EMC92626.1 - 3.9e-12 45.6 0.1 7.1e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.1 EMC92626.1 - 7.9e-10 37.8 0.5 0.00067 19.2 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC92626.1 - 9.8e-08 31.8 0.7 3.4e-07 30.0 0.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC92626.1 - 1.3e-07 31.6 1.7 0.52 10.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC92626.1 - 5.2e-05 23.1 0.4 0.03 14.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC92626.1 - 0.00045 19.8 0.2 0.021 14.5 0.0 3.3 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC92626.1 - 0.0056 17.3 8.2 0.0078 16.8 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC92626.1 - 0.0062 16.3 3.1 3.9 7.3 0.2 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC92626.1 - 0.057 14.0 3.1 0.17 12.5 0.1 3.2 2 1 1 3 3 2 0 Tetratricopeptide repeat LON PF02190.11 EMC92627.1 - 3.2e-24 85.7 0.0 4.7e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EMC92627.1 - 4.2e-11 42.6 24.3 1.7e-07 31.1 7.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC92627.1 - 8e-11 41.4 22.3 9.5e-07 28.4 6.6 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC92627.1 - 1.1e-10 41.1 17.3 4.9e-07 29.5 4.4 2.9 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC92627.1 - 2.2e-10 40.1 25.0 9.4e-07 28.5 8.1 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 EMC92627.1 - 3.1e-10 39.5 19.8 9.6e-07 28.3 7.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC92627.1 - 2.3e-08 33.5 20.3 1.1e-06 28.2 5.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC92627.1 - 3.2e-08 33.1 13.2 2.1e-06 27.3 2.4 2.7 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_4 PF14570.1 EMC92627.1 - 0.002 17.6 5.6 0.002 17.6 3.9 3.5 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain U-box PF04564.10 EMC92627.1 - 0.0038 17.1 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-RING_6 PF14835.1 EMC92627.1 - 0.0048 16.6 11.7 0.033 13.9 1.9 2.5 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-P11 PF03854.9 EMC92627.1 - 0.016 14.7 8.3 0.016 14.7 5.7 2.8 2 1 1 3 3 3 0 P-11 zinc finger Elf1 PF05129.8 EMC92627.1 - 1.5 8.5 4.6 2.5 7.8 0.3 3.1 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Baculo_IE-1 PF05290.6 EMC92627.1 - 2.4 7.8 7.4 0.14 11.8 0.3 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Sod_Cu PF00080.15 EMC92628.1 - 1.2e-15 57.9 0.0 1.8e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EMC92628.1 - 5.3e-12 45.7 0.0 8.9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_L13 PF00572.13 EMC92629.1 - 1.1e-43 148.3 0.0 1.3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 EMC92630.1 - 2.9e-85 283.3 1.0 8.2e-44 149.0 0.6 2.0 2 0 0 2 2 2 2 Uricase DUF3225 PF11533.3 EMC92630.1 - 0.1 12.3 0.3 0.86 9.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3225) RICTOR_N PF14664.1 EMC92631.1 - 1.5e-121 405.5 0.7 1.1e-120 402.6 0.3 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EMC92631.1 - 4.5e-82 274.4 1.4 1.2e-81 273.0 0.3 2.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EMC92631.1 - 3.3e-41 139.8 0.0 6.8e-40 135.5 0.0 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EMC92631.1 - 5.7e-29 99.8 1.1 9.2e-26 89.5 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EMC92631.1 - 1.5e-06 27.8 12.9 3.3e-06 26.7 9.0 1.6 1 0 0 1 1 1 1 Hr1 repeat MFS_1 PF07690.11 EMC92632.1 - 2e-24 86.0 26.2 2e-24 86.0 18.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosyl_trans3 PF11051.3 EMC92633.1 - 1.7e-71 240.7 0.0 1.1e-70 238.0 0.0 2.2 2 1 0 2 2 2 1 Mannosyltransferase putative Poty_PP PF08440.5 EMC92633.1 - 0.072 12.1 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein CN_hydrolase PF00795.17 EMC92635.1 - 2.3e-23 82.4 0.1 3e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Endonuclease_NS PF01223.18 EMC92635.1 - 0.038 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Paf67 PF10255.4 EMC92636.1 - 1.2e-150 501.9 0.3 1.3e-150 501.7 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EMC92636.1 - 0.0017 18.0 0.0 0.0098 15.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC92636.1 - 0.014 14.9 0.0 0.071 12.7 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC92636.1 - 0.02 14.8 0.7 0.12 12.3 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1418 PF07214.7 EMC92637.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) MRP-S27 PF10037.4 EMC92637.1 - 0.13 11.1 0.1 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 HET PF06985.6 EMC92640.1 - 7.9e-20 71.4 0.0 9.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ala_racemase_N PF01168.15 EMC92641.1 - 8.4e-45 152.9 0.1 9.7e-45 152.7 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MAPEG PF01124.13 EMC92642.1 - 1.4e-16 60.2 0.8 1.8e-16 59.9 0.5 1.2 1 0 0 1 1 1 1 MAPEG family Longin PF13774.1 EMC92643.1 - 7.5e-17 60.6 0.0 1.3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EMC92643.1 - 2.8e-11 42.8 0.1 4.9e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EMC92643.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 RCC1 PF00415.13 EMC92644.1 - 1.1e-32 111.9 24.4 2e-10 40.6 0.6 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC92644.1 - 6.6e-24 82.9 32.7 6.1e-09 35.2 0.5 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 EMC92645.1 - 4.3e-13 48.9 0.0 4.9e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Rad9 Phos_pyr_kin PF08543.7 EMC92647.1 - 2.4e-79 266.0 0.5 4.1e-79 265.2 0.3 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EMC92647.1 - 8.6e-52 175.9 1.0 1.1e-51 175.5 0.7 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EMC92647.1 - 1.7e-07 30.6 0.1 3e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Neur_chan_memb PF02932.11 EMC92649.1 - 0.33 10.8 2.2 0.43 10.4 1.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1682 PF07946.9 EMC92649.1 - 0.7 8.6 7.2 0.85 8.4 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PAT1 PF09770.4 EMC92649.1 - 4.6 5.3 29.7 4.9 5.2 20.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DEAD PF00270.24 EMC92651.1 - 7.5e-46 155.7 0.0 2.8e-44 150.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC92651.1 - 3.4e-29 100.5 0.1 1.5e-28 98.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC92651.1 - 0.00013 21.8 0.0 0.0007 19.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EMC92651.1 - 0.0006 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_19 PF13245.1 EMC92651.1 - 0.021 14.5 0.0 0.59 9.9 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Desmo_N PF06771.6 EMC92651.1 - 0.038 13.8 0.3 2.3 8.1 0.0 2.6 2 1 0 2 2 2 0 Viral Desmoplakin N-terminus TT_ORF2 PF02957.10 EMC92652.1 - 0.038 14.6 0.3 0.052 14.2 0.2 1.4 1 1 0 1 1 1 0 TT viral ORF2 Ndufs5 PF10200.4 EMC92652.1 - 0.088 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Utp21 PF04192.7 EMC92653.1 - 6.3e-67 225.1 0.1 9.8e-67 224.5 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EMC92653.1 - 3.8e-20 70.9 18.6 0.001 18.8 0.2 8.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Glyco_trans_2_3 PF13632.1 EMC92654.1 - 4e-45 153.9 6.0 4e-45 153.9 4.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC92654.1 - 3.8e-05 23.6 0.0 0.004 16.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC92654.1 - 0.098 12.3 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 ShK PF01549.19 EMC92655.1 - 0.056 13.7 1.3 0.16 12.3 0.2 2.1 2 0 0 2 2 2 0 ShK domain-like Glyco_hydro_16 PF00722.16 EMC92656.1 - 5.1e-21 74.8 0.4 1e-20 73.8 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 WSC PF01822.14 EMC92658.1 - 5.6e-82 269.7 91.4 2.2e-18 65.9 8.2 5.4 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 EMC92658.1 - 3.8e-24 85.0 0.0 8.6e-22 77.3 0.0 3.1 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EMC92658.1 - 2.5e-22 78.7 0.0 4.9e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Methyltransf_15 PF09445.5 EMC92663.1 - 0.031 13.8 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase SAC3_GANP PF03399.11 EMC92664.1 - 0.055 13.0 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family dsDNA_bind PF01984.15 EMC92664.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Dus PF01207.12 EMC92665.1 - 2.1e-54 184.4 0.0 2.9e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Glycos_transf_2 PF00535.21 EMC92666.1 - 1.1e-29 103.3 0.0 2.1e-29 102.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMC92666.1 - 3.1e-11 43.5 0.0 1.8e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMC92666.1 - 6.5e-06 25.5 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EMC92666.1 - 2.3e-05 23.6 0.0 0.00046 19.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cyclin_N PF00134.18 EMC92667.1 - 0.00084 18.8 0.0 0.0058 16.2 0.0 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EMC92667.1 - 0.073 12.8 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Sugar_tr PF00083.19 EMC92668.1 - 7.5e-64 215.9 29.1 8.6e-64 215.7 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC92668.1 - 1.9e-09 36.7 46.2 3.9e-08 32.3 27.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC92668.1 - 0.00011 20.7 5.1 0.00011 20.7 3.5 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein DUF4535 PF15054.1 EMC92668.1 - 0.79 9.1 2.8 0.96 8.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) PSII_Ycf12 PF05969.6 EMC92668.1 - 1.7 8.3 6.4 0.22 11.1 0.5 2.4 2 0 0 2 2 2 0 Photosystem II complex subunit Ycf12 Ferritin_2 PF13668.1 EMC92669.1 - 3.6e-19 69.0 0.0 6.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain TRM PF02005.11 EMC92670.1 - 4.1e-110 368.2 0.0 1.4e-93 313.8 0.0 2.0 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 EMC92670.1 - 0.00078 18.8 0.0 0.0022 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMC92670.1 - 0.014 15.4 0.1 0.053 13.5 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMC92670.1 - 0.016 14.7 0.0 0.041 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EMC92670.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.2 EMC92670.1 - 0.028 15.0 0.0 0.088 13.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 EMC92670.1 - 0.032 13.3 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ISN1 PF06437.6 EMC92671.1 - 1.7e-185 616.5 0.0 1.9e-185 616.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Ribosomal_S5 PF00333.15 EMC92671.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Med17 PF10156.4 EMC92672.1 - 5.8e-82 275.4 0.0 8.9e-82 274.8 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 EMC92673.1 - 9.8e-169 559.5 1.6 2.7e-121 403.8 0.7 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 EMC92673.1 - 0.084 11.6 0.3 0.38 9.4 0.1 1.9 2 0 0 2 2 2 0 ATP-NAD kinase PI3_PI4_kinase PF00454.22 EMC92674.1 - 1.9e-51 174.7 0.0 3.5e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EMC92674.1 - 6e-29 101.1 1.4 1.2e-28 100.1 1.0 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EMC92674.1 - 6.3e-23 80.7 0.1 2.3e-22 78.9 0.1 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 EMC92674.1 - 2.7e-13 49.0 0.0 6.1e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 FATC domain NAD_binding_3 PF03447.11 EMC92674.1 - 0.08 13.3 0.1 0.56 10.6 0.0 2.5 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain MS_channel PF00924.13 EMC92675.1 - 1.8e-15 56.8 3.2 3.3e-15 55.9 2.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EMC92675.1 - 2e-05 23.5 0.1 5.1e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EMC92675.1 - 0.0045 16.7 0.1 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EMC92675.1 - 0.0055 16.8 0.1 0.014 15.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC92675.1 - 0.021 14.1 0.1 0.048 13.0 0.1 1.6 1 0 0 1 1 1 0 EF hand DUF1189 PF06691.6 EMC92675.1 - 0.035 13.4 0.3 0.061 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Metallophos PF00149.23 EMC92676.1 - 2.1e-23 82.7 1.6 2.1e-23 82.7 1.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EMC92676.1 - 6.1e-17 61.4 0.4 6.1e-17 61.4 0.3 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EMC92676.1 - 1.1e-05 24.1 0.6 1.1e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EMC92676.1 - 0.0027 17.5 0.0 0.0062 16.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Hexokinase_2 PF03727.11 EMC92677.1 - 8.9e-32 110.2 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EMC92677.1 - 5.9e-14 51.8 0.0 8.2e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.11 EMC92678.1 - 2.2e-10 39.8 32.7 3.6e-10 39.1 22.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMC92678.1 - 1.3e-08 34.4 9.2 1.3e-08 34.4 6.4 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Glucosamine_iso PF01182.15 EMC92679.1 - 1.4e-22 80.4 0.0 2.2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ATG22 PF11700.3 EMC92680.1 - 3.3e-131 438.0 32.9 3.8e-131 437.8 22.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EMC92680.1 - 4.2e-10 38.8 37.6 3.6e-07 29.2 5.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily AAA_11 PF13086.1 EMC92681.1 - 1.8e-26 93.1 0.0 4e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EMC92681.1 - 3.3e-26 91.9 0.0 7.2e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC92681.1 - 2.2e-09 36.9 0.1 8.2e-09 35.1 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMC92681.1 - 1.1e-06 28.3 0.3 0.0013 18.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EMC92681.1 - 0.00039 20.3 0.0 0.00089 19.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EMC92681.1 - 0.00049 19.5 0.0 0.0018 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EMC92681.1 - 0.0011 19.1 0.0 0.0033 17.5 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.24 EMC92681.1 - 0.0065 15.9 0.1 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.1 EMC92681.1 - 0.012 15.5 0.5 7.6 6.4 0.0 3.8 3 1 1 4 4 4 0 AAA domain AAA_16 PF13191.1 EMC92681.1 - 0.015 15.3 0.1 0.015 15.3 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EMC92681.1 - 0.025 14.7 0.0 0.2 11.8 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC92681.1 - 0.082 13.0 0.0 0.51 10.4 0.0 2.4 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EMC92681.1 - 0.11 11.7 0.0 0.31 10.3 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Arch_ATPase PF01637.13 EMC92681.1 - 0.19 11.4 0.0 0.57 9.8 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 EMC92681.1 - 0.22 10.9 0.1 18 4.7 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Usp PF00582.21 EMC92682.1 - 2.2e-22 79.7 0.0 2.8e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family ABA_GPCR PF12430.3 EMC92683.1 - 1.9e-50 170.7 0.1 1.9e-50 170.7 0.1 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EMC92683.1 - 2.8e-19 68.9 0.1 1.7e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) HlyD PF00529.15 EMC92683.1 - 0.15 11.3 6.2 0.26 10.5 4.3 1.3 1 0 0 1 1 1 0 HlyD family secretion protein FAD_binding_3 PF01494.14 EMC92684.1 - 2.2e-21 76.3 0.8 1.1e-20 73.9 0.5 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC92684.1 - 4.8e-06 25.7 3.0 0.0024 16.8 0.5 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC92684.1 - 3.1e-05 23.9 0.7 7.9e-05 22.6 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMC92684.1 - 0.00015 20.7 0.0 0.00091 18.1 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.12 EMC92684.1 - 0.0014 17.7 0.1 0.0025 16.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DUF2007 PF09413.5 EMC92684.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2007) Pyr_redox_3 PF13738.1 EMC92684.1 - 0.024 14.7 0.3 0.1 12.6 0.2 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC92684.1 - 0.075 12.7 0.4 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EMC92684.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EMC92684.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EMC92684.1 - 0.11 10.9 0.1 0.16 10.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.13 EMC92685.1 - 4.1e-12 45.5 0.0 7.1e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC92685.1 - 0.054 13.4 1.9 0.14 12.1 1.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMC92686.1 - 1.1e-13 51.4 2.6 3.3e-13 49.8 0.3 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92686.1 - 1.7e-06 28.0 0.1 6.4e-05 22.8 0.0 2.5 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92686.1 - 0.00011 21.9 0.0 0.00023 20.8 0.0 1.6 1 1 0 1 1 1 1 KR domain WGG PF10273.4 EMC92687.1 - 7.9e-31 105.9 0.4 1.2e-30 105.4 0.2 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 COPI_C PF06957.6 EMC92687.1 - 1.8 6.9 4.4 2.1 6.7 3.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EMC92688.1 - 2e-07 30.6 3.2 0.00024 20.8 0.0 5.3 4 1 0 4 4 4 1 WD domain, G-beta repeat Caldesmon PF02029.10 EMC92688.1 - 5.3 5.3 13.0 8 4.7 9.0 1.1 1 0 0 1 1 1 0 Caldesmon RNA_pol_N PF01194.12 EMC92689.1 - 8.5e-29 99.3 0.3 1e-28 99.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Acetyltransf_7 PF13508.1 EMC92690.1 - 6.5e-08 32.6 0.0 1.5e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC92690.1 - 3.2e-05 23.8 0.0 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMC92690.1 - 0.0015 18.3 0.0 0.0059 16.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC92690.1 - 0.0048 17.0 0.1 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC92690.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein zf-PARP PF00645.13 EMC92692.1 - 1.5e-21 76.3 0.3 2.9e-21 75.4 0.2 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MCLC PF05934.6 EMC92692.1 - 2.2 6.4 8.7 3.4 5.8 6.1 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) CHZ PF09649.5 EMC92693.1 - 2.4 7.4 5.3 0.46 9.7 0.8 1.9 2 0 0 2 2 2 0 Histone chaperone domain CHZ Abhydrolase_3 PF07859.8 EMC92694.1 - 1.1e-38 132.9 0.0 5.1e-38 130.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMC92694.1 - 1.9e-06 26.7 0.0 3.9e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EMC92694.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cation_efflux PF01545.16 EMC92695.1 - 2.4e-28 99.0 5.2 3.7e-28 98.4 3.6 1.2 1 0 0 1 1 1 1 Cation efflux family PIG-Y PF15159.1 EMC92696.1 - 1.7 8.8 6.0 4 7.7 4.1 1.7 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y MIF4G PF02854.14 EMC92697.1 - 9.9e-51 172.1 0.1 1.1e-50 171.9 0.1 1.0 1 0 0 1 1 1 1 MIF4G domain Eno-Rase_FAD_bd PF07055.7 EMC92697.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Cnd1 PF12717.2 EMC92697.1 - 0.027 14.3 0.2 0.26 11.1 0.0 2.3 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF496 PF04363.7 EMC92697.1 - 0.032 14.0 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Neisseria_TspB PF05616.8 EMC92697.1 - 0.075 11.3 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF2097 PF09870.4 EMC92697.1 - 0.083 12.9 0.1 0.29 11.2 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) Homeobox PF00046.24 EMC92698.1 - 1e-17 63.4 2.8 3e-17 61.9 2.0 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC92698.1 - 0.0035 16.9 0.2 0.0093 15.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain efThoc1 PF11957.3 EMC92699.1 - 1.3e-129 432.8 0.0 1.5e-129 432.6 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor CopC PF04234.7 EMC92701.1 - 0.023 15.3 0.8 0.95 10.1 0.0 2.5 2 1 0 2 2 2 0 CopC domain DUF2458 PF10454.4 EMC92702.1 - 9.5e-14 51.5 0.2 2.2e-13 50.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) CHASE4 PF05228.8 EMC92702.1 - 0.14 11.6 0.2 0.26 10.8 0.1 1.4 1 1 0 1 1 1 0 CHASE4 domain COX14 PF14880.1 EMC92703.1 - 2.7e-12 46.0 0.3 7.6e-12 44.6 0.0 1.9 1 1 1 2 2 2 1 Cytochrome oxidase c assembly DUF2561 PF10812.3 EMC92703.1 - 0.14 11.7 5.2 0.31 10.6 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) Aminotran_5 PF00266.14 EMC92704.1 - 3e-11 42.6 0.0 4.4e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMC92704.1 - 0.0033 16.5 0.4 0.0054 15.8 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family ATG11 PF10377.4 EMC92705.1 - 2.7e-32 111.3 0.0 2.7e-32 111.3 0.0 3.2 2 1 0 2 2 2 1 Autophagy-related protein 11 Pox_A_type_inc PF04508.7 EMC92705.1 - 0.16 11.8 8.6 0.63 9.9 0.8 4.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PGM_PMM_I PF02878.11 EMC92706.1 - 3.9e-33 113.8 0.1 5.8e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EMC92706.1 - 1e-24 86.7 0.0 1.9e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EMC92706.1 - 2.6e-15 56.6 0.1 6.8e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMC92706.1 - 1.5e-10 40.9 0.0 3.6e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fe-S_biosyn PF01521.15 EMC92707.1 - 1.9e-11 43.8 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pectinesterase PF01095.14 EMC92708.1 - 4.9e-21 74.5 1.0 9e-19 67.1 0.2 2.1 2 0 0 2 2 2 2 Pectinesterase DUF1996 PF09362.5 EMC92709.1 - 7.8e-54 182.8 0.1 9.5e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NDT80_PhoG PF05224.7 EMC92710.1 - 1.9e-32 112.7 0.0 3e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.16 EMC92711.1 - 9.5e-54 182.3 0.0 1.4e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EMC92711.1 - 0.00058 19.8 0.0 0.0055 16.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC92711.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EMC92711.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Amidohydro_1 PF01979.15 EMC92712.1 - 2.1e-11 44.0 0.1 3.8e-10 39.9 0.1 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC92712.1 - 1.6e-10 41.5 0.0 9.2e-05 22.5 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EMC92712.1 - 6.4e-06 25.8 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC92712.1 - 8e-06 25.3 0.0 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family ABC1 PF03109.11 EMC92713.1 - 4.9e-23 81.3 0.0 2.7e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.17 EMC92713.1 - 0.0044 16.3 0.0 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EMC92713.1 - 0.0091 15.7 0.5 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTO_CTD PF12934.2 EMC92715.1 - 0.18 11.4 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 FTO C-terminal domain Tfb2 PF03849.9 EMC92716.1 - 2e-132 441.2 0.0 2.8e-132 440.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EMC92716.1 - 4.7e-05 23.1 0.0 9.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 EMC92716.1 - 0.05 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI HMG_CoA_synt_C PF08540.5 EMC92718.1 - 3.8e-103 344.8 0.4 4.8e-103 344.5 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EMC92718.1 - 3.8e-91 303.3 0.0 6e-91 302.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal dCMP_cyt_deam_1 PF00383.17 EMC92720.1 - 1.4e-25 88.8 0.0 2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMC92720.1 - 0.00072 19.4 0.5 0.022 14.6 0.3 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase Pkinase PF00069.20 EMC92721.1 - 5.8e-53 179.6 0.0 1.4e-52 178.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92721.1 - 1e-23 83.7 0.3 2e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMC92721.1 - 0.0041 16.8 0.1 0.0041 16.8 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC92721.1 - 0.0092 15.3 0.2 0.045 13.1 0.1 2.0 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EMC92721.1 - 0.033 14.2 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) DUF1765 PF08578.5 EMC92722.1 - 5.1e-38 129.9 1.2 1.9e-37 128.1 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) HlyIII PF03006.15 EMC92723.1 - 7.3e-63 211.9 11.0 8.5e-63 211.7 7.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4401 PF14351.1 EMC92723.1 - 0.12 11.3 9.6 0.022 13.7 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) ABC2_membrane_5 PF13346.1 EMC92723.1 - 9.5 5.4 7.6 10 5.3 4.1 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2235 PF09994.4 EMC92724.1 - 3.4e-66 223.4 0.0 4.3e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Tropomodulin PF03250.9 EMC92724.1 - 0.049 13.1 0.1 0.37 10.2 0.0 2.2 3 0 0 3 3 3 0 Tropomodulin Ndc80_HEC PF03801.8 EMC92725.1 - 7.2e-53 178.2 0.1 7.2e-53 178.2 0.0 2.1 3 0 0 3 3 3 1 HEC/Ndc80p family Atg14 PF10186.4 EMC92725.1 - 0.29 10.0 27.1 0.48 9.3 9.7 2.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 EMC92725.1 - 9.3 5.4 34.2 0.016 14.4 5.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) FAT PF02259.18 EMC92726.1 - 2.4e-120 401.7 0.2 2.4e-120 401.7 0.2 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EMC92726.1 - 1.2e-62 211.5 0.4 2.1e-62 210.6 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EMC92726.1 - 2e-55 187.0 7.2 2.3e-52 177.1 0.1 6.5 6 3 1 7 7 7 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EMC92726.1 - 2.2e-43 146.4 0.9 1.9e-41 140.1 0.0 3.6 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EMC92726.1 - 2e-15 56.8 16.2 0.0059 16.8 0.0 9.9 7 2 3 10 10 10 5 HEAT repeats FATC PF02260.15 EMC92726.1 - 3.9e-15 54.9 0.1 9.8e-15 53.6 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EMC92726.1 - 5.4e-10 38.5 20.9 5 7.4 0.0 12.6 13 0 0 13 13 13 4 HEAT repeat HEAT_EZ PF13513.1 EMC92726.1 - 2.5e-06 27.7 14.0 3.5 8.2 0.0 10.3 11 0 0 11 11 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMC92726.1 - 3e-06 27.5 6.4 6.2 7.2 0.0 7.9 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EMC92726.1 - 1.4e-05 24.5 3.4 0.29 10.4 0.0 4.7 4 1 0 4 4 4 2 CLASP N terminal Adaptin_N PF01602.15 EMC92726.1 - 3.4e-05 22.3 6.5 0.062 11.6 0.0 5.1 4 1 1 5 5 5 2 Adaptin N terminal region ParcG PF10274.4 EMC92726.1 - 0.0017 18.2 8.5 0.19 11.6 0.1 5.2 5 0 0 5 5 5 1 Parkin co-regulated protein Peptidase_S24 PF00717.18 EMC92727.1 - 4.9e-08 32.5 0.0 6.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF1768 PF08719.6 EMC92728.1 - 1.2e-52 177.7 0.5 1.4e-52 177.6 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) FCH PF00611.18 EMC92729.1 - 4e-20 71.7 0.0 3.4e-19 68.8 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.5 EMC92729.1 - 0.31 10.2 6.4 0.56 9.4 1.4 2.6 2 0 0 2 2 2 0 Vps5 C terminal like IBR PF01485.16 EMC92730.1 - 1e-19 70.1 30.1 4.3e-11 42.5 6.0 3.8 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 EMC92730.1 - 2.2 7.9 30.5 0.075 12.7 2.0 4.0 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Cg6151-P PF10233.4 EMC92731.1 - 4.8e-39 132.8 17.1 5.8e-39 132.5 11.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B_N PF00033.14 EMC92731.1 - 0.0033 16.7 2.0 0.0033 16.7 1.4 2.3 1 1 1 2 2 2 1 Cytochrome b(N-terminal)/b6/petB T_cell_tran_alt PF15128.1 EMC92731.1 - 0.047 13.1 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Cytochrom_B558a PF05038.8 EMC92731.1 - 0.3 10.6 7.0 0.11 12.1 1.2 2.2 2 1 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit PEMT PF04191.8 EMC92731.1 - 3.5 7.7 10.0 1.3 9.1 1.5 2.4 2 0 0 2 2 2 0 Phospholipid methyltransferase IBN_N PF03810.14 EMC92732.1 - 1.4e-15 56.9 0.0 1e-12 47.8 0.0 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 EMC92732.1 - 3.5e-05 22.5 0.0 7.7e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Cse1 DUF2435 PF10363.4 EMC92732.1 - 0.0047 16.8 0.4 0.017 15.0 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) Xpo1 PF08389.7 EMC92732.1 - 0.037 13.9 4.6 0.44 10.4 0.1 4.3 5 1 0 5 5 5 0 Exportin 1-like protein BUD22 PF09073.5 EMC92732.1 - 0.12 11.3 6.6 0.2 10.7 4.6 1.3 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.11 EMC92733.1 - 7e-22 77.6 50.6 3.4e-20 72.0 28.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC92733.1 - 9.6e-07 27.7 9.7 9.6e-07 27.7 6.7 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter Vps35 PF03635.12 EMC92735.1 - 1.8e-303 1008.5 0.1 2e-303 1008.3 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Swi3 PF07962.7 EMC92737.1 - 2.6e-29 100.6 0.1 4.3e-29 99.9 0.1 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Pkinase PF00069.20 EMC92738.1 - 8.5e-67 225.0 0.0 1.1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92738.1 - 1.6e-31 109.3 0.0 2.3e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC92738.1 - 0.016 14.1 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EMC92738.1 - 0.13 11.9 0.3 1.3 8.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.15 EMC92739.1 - 5.2e-131 437.4 0.1 6e-131 437.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 EMC92739.1 - 0.085 13.1 0.1 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Fungal_trans PF04082.13 EMC92740.1 - 7.5e-06 25.0 0.1 1.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAAP1 PF15335.1 EMC92740.1 - 0.06 13.5 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 HTH_29 PF13551.1 EMC92741.1 - 2e-06 27.9 0.8 3.5e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EMC92741.1 - 3.2e-05 24.6 0.9 0.0027 18.4 0.0 3.1 3 1 1 4 4 4 1 Homeodomain-like domain HTH_7 PF02796.10 EMC92741.1 - 4.4e-05 23.2 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EMC92741.1 - 0.01 15.4 0.0 0.041 13.5 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain PAX PF00292.13 EMC92741.1 - 0.05 13.3 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain Trp_repressor PF01371.14 EMC92741.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein DHquinase_II PF01220.14 EMC92743.1 - 2.3e-60 201.9 0.0 2.7e-60 201.7 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Dioxygenase_C PF00775.16 EMC92744.1 - 1.4e-51 174.3 0.0 1.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EMC92744.1 - 1.5e-17 63.3 0.0 2.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SnoaL_4 PF13577.1 EMC92747.1 - 7.8e-05 22.5 0.5 0.00015 21.7 0.3 1.4 1 0 0 1 1 1 1 SnoaL-like domain Ras PF00071.17 EMC92748.1 - 1.8e-49 167.2 0.0 1.1e-47 161.3 0.0 2.3 2 0 0 2 2 2 1 Ras family DHquinase_I PF01487.10 EMC92748.1 - 2.3e-21 76.4 0.0 3.8e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EMC92748.1 - 5.8e-17 61.5 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Miro PF08477.8 EMC92748.1 - 2.9e-16 60.0 0.0 8.7e-14 52.0 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein SKI PF01202.17 EMC92748.1 - 2.1e-13 50.4 0.0 6.1e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 EMC92748.1 - 3.9e-10 39.9 0.0 1.4e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Arf PF00025.16 EMC92748.1 - 2.8e-05 23.4 0.0 4.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 EMC92748.1 - 0.0043 17.0 0.2 1 9.3 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 EMC92748.1 - 0.017 14.5 0.0 0.075 12.4 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC92748.1 - 0.036 14.0 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC92748.1 - 0.038 13.1 0.2 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EMC92748.1 - 0.08 13.2 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.5 EMC92748.1 - 0.19 10.9 0.0 0.69 9.1 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EMC92748.1 - 0.2 11.5 0.1 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NST1 PF13945.1 EMC92750.1 - 6.1e-53 179.7 3.0 6.1e-53 179.7 2.1 5.7 4 2 2 6 6 6 1 Salt tolerance down-regulator ADH_zinc_N PF00107.21 EMC92751.1 - 2.3e-17 62.7 0.0 5.9e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC92751.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EMC92751.1 - 0.063 13.1 0.5 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Shadoo PF14999.1 EMC92754.1 - 2.2 8.1 10.1 2.3 8.1 7.0 1.4 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective Abhydrolase_6 PF12697.2 EMC92756.1 - 7.2e-26 91.4 5.4 8.7e-25 87.9 3.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC92756.1 - 9.4e-07 28.6 0.0 6.7e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC92756.1 - 5.9e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EMC92756.1 - 0.17 11.8 1.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Mgm101p PF06420.7 EMC92757.1 - 1.4e-87 291.3 0.0 1.8e-87 291.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.4 EMC92758.1 - 9e-135 449.1 0.0 1.2e-134 448.7 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EMC92758.1 - 4e-17 62.4 0.1 1.3e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Pex24p PF06398.6 EMC92759.1 - 2.3e-84 283.2 0.9 3.1e-84 282.8 0.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Wzy_C PF04932.10 EMC92759.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 O-Antigen ligase Pam16 PF03656.8 EMC92760.1 - 4.5e-35 120.2 0.9 5.4e-35 119.9 0.6 1.0 1 0 0 1 1 1 1 Pam16 APC_CDC26 PF10471.4 EMC92760.1 - 2 9.2 7.8 3.9 8.2 2.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 BAT2_N PF07001.6 EMC92761.1 - 0.04 14.2 3.2 0.047 14.0 2.3 1.0 1 0 0 1 1 1 0 BAT2 N-terminus LEA_6 PF10714.4 EMC92761.1 - 2.6 7.9 7.5 0.26 11.1 1.2 2.1 1 1 1 2 2 2 0 Late embryogenesis abundant protein 18 HA2 PF04408.18 EMC92762.1 - 1.9e-18 66.3 0.2 5.7e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMC92762.1 - 1.1e-13 50.8 0.0 3.4e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EMC92762.1 - 4.6e-11 42.5 0.0 3.5e-10 39.7 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EMC92762.1 - 7.5e-08 32.0 0.0 2.4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 EMC92762.1 - 0.00061 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family dsrm PF00035.20 EMC92762.1 - 0.0018 18.8 5.0 0.14 12.7 0.0 3.7 4 0 0 4 4 4 1 Double-stranded RNA binding motif AAA_22 PF13401.1 EMC92762.1 - 0.015 15.4 0.0 0.077 13.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_5 PF13873.1 EMC92762.1 - 0.14 12.0 1.2 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain BCS1_N PF08740.6 EMC92763.1 - 3.6e-41 140.8 0.1 5e-41 140.3 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMC92763.1 - 3.1e-19 69.4 0.0 6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC92763.1 - 5e-05 23.0 0.0 0.00014 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMC92763.1 - 5.1e-05 24.0 0.0 0.00016 22.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EMC92763.1 - 7.3e-05 22.2 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC92763.1 - 0.0007 19.6 0.2 0.0052 16.7 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC92763.1 - 0.0032 17.6 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC92763.1 - 0.005 16.7 0.0 0.03 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EMC92763.1 - 0.009 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.1 EMC92763.1 - 0.011 15.3 0.2 0.032 13.7 0.1 1.8 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.8 EMC92763.1 - 0.013 14.4 0.0 0.026 13.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EMC92763.1 - 0.015 15.0 0.2 0.07 12.8 0.1 2.2 1 1 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EMC92763.1 - 0.021 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_21 PF13304.1 EMC92763.1 - 0.048 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC92763.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EMC92763.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EMC92763.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EMC92763.1 - 0.21 10.1 0.0 0.32 9.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase RRM_6 PF14259.1 EMC92764.1 - 0.0039 17.1 0.0 0.83 9.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TBPIP PF07106.8 EMC92767.1 - 0.22 11.0 3.0 1 8.8 0.1 2.8 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) USP8_interact PF08941.5 EMC92767.1 - 1.2 8.4 4.3 0.32 10.2 0.0 2.1 3 0 0 3 3 3 0 USP8 interacting IncA PF04156.9 EMC92767.1 - 3 7.3 6.1 16 5.0 0.0 3.2 3 0 0 3 3 3 0 IncA protein P16-Arc PF04699.9 EMC92768.1 - 3.1e-55 186.3 0.0 3.6e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UQ_con PF00179.21 EMC92769.1 - 4e-24 84.6 0.0 5.8e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PDH PF02153.12 EMC92770.1 - 2.7e-13 49.4 0.1 3.9e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EMC92770.1 - 1.3e-06 28.7 0.1 4.5e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMC92770.1 - 2e-06 27.7 0.0 3.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EMC92770.1 - 0.00047 19.3 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMC92770.1 - 0.0006 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EMC92770.1 - 0.0042 16.5 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.4 EMC92770.1 - 0.015 15.0 0.1 0.036 13.8 0.1 1.6 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.13 EMC92770.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain CFEM PF05730.6 EMC92772.1 - 2.8e-10 39.8 7.8 5.8e-10 38.8 5.4 1.5 1 0 0 1 1 1 1 CFEM domain DUF4118 PF13493.1 EMC92772.1 - 2.3 8.4 6.3 0.18 12.0 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) p450 PF00067.17 EMC92773.1 - 9.8e-67 225.4 0.1 1.7e-66 224.6 0.0 1.3 2 0 0 2 2 2 1 Cytochrome P450 TDH PF03347.8 EMC92773.1 - 0.029 13.9 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Lactamase_B_2 PF12706.2 EMC92774.1 - 1.3e-39 135.7 0.3 1.7e-39 135.4 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC92774.1 - 1.7e-10 40.8 0.0 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC92774.1 - 0.00017 21.3 2.2 0.0022 17.6 1.6 2.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Thiolase_N PF00108.18 EMC92778.1 - 4.2e-82 275.0 0.1 5.7e-82 274.6 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC92778.1 - 6.3e-44 148.3 0.5 2e-43 146.7 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMC92778.1 - 0.0053 16.2 0.9 0.016 14.7 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF3245 PF11595.3 EMC92779.1 - 5.6e-13 49.4 21.1 4.5e-12 46.4 14.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) DUF572 PF04502.8 EMC92779.1 - 0.25 10.5 14.9 0.33 10.1 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CBFD_NFYB_HMF PF00808.18 EMC92780.1 - 5.2e-14 52.0 5.1 1.5e-12 47.3 3.6 2.2 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 EMC92780.1 - 0.0017 18.0 0.0 0.0032 17.2 0.0 1.5 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EMC92780.1 - 0.0086 16.1 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4415 PF14384.1 EMC92780.1 - 0.084 13.0 0.2 8.9 6.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4415) MRP-S27 PF10037.4 EMC92780.1 - 0.12 11.3 0.6 0.14 11.0 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Mid2 PF04478.7 EMC92781.1 - 0.0051 16.2 0.2 0.0051 16.2 0.1 2.1 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EMC92781.1 - 0.059 12.7 0.1 0.19 11.1 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Acetyltransf_1 PF00583.19 EMC92782.1 - 3.5e-16 58.9 0.1 5.3e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMC92782.1 - 4.2e-11 42.7 0.1 2.5e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC92782.1 - 6.8e-11 42.1 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC92782.1 - 1.3e-09 38.2 0.1 2e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC92782.1 - 1.2e-06 28.2 0.1 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EMC92782.1 - 3.4e-05 23.7 0.0 4.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC92782.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EMC92782.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 EMC92783.1 - 3.8e-11 42.3 0.1 6.1e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC92783.1 - 1.6e-06 27.8 6.6 2.7e-06 27.1 4.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFR_dimer PF04253.10 EMC92784.1 - 1.2e-18 66.8 0.0 3.5e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMC92784.1 - 6.5e-11 42.2 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMC92784.1 - 0.00022 20.8 0.0 0.00048 19.7 0.0 1.5 1 0 0 1 1 1 1 PA domain GFO_IDH_MocA PF01408.17 EMC92785.1 - 3.3e-13 50.1 0.0 7.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMC92785.1 - 0.00013 21.7 0.0 0.00067 19.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Cyto_heme_lyase PF01265.12 EMC92786.1 - 6e-74 248.8 0.0 6.9e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Ribonucleas_3_3 PF14622.1 EMC92787.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMC92787.1 - 0.00045 20.6 0.0 0.0041 17.5 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Mid1 PF12929.2 EMC92788.1 - 0.00053 18.8 0.1 0.00064 18.5 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component POM121 PF15229.1 EMC92788.1 - 0.027 13.9 0.3 0.044 13.2 0.2 1.3 1 0 0 1 1 1 0 POM121 family Gag_p24 PF00607.15 EMC92788.1 - 0.048 13.1 1.6 0.11 12.0 1.1 1.6 1 1 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) DUF3210 PF11489.3 EMC92790.1 - 5e-147 491.5 79.4 6.2e-144 481.3 55.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3210) Inositol_P PF00459.20 EMC92793.1 - 4.3e-71 239.4 0.0 4.8e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family AcetDehyd-dimer PF09290.6 EMC92793.1 - 0.16 11.8 0.4 0.5 10.2 0.2 1.8 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation HSF_DNA-bind PF00447.12 EMC92794.1 - 1.8e-31 108.3 0.5 1.2e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 HSF-type DNA-binding EzrA PF06160.7 EMC92794.1 - 0.27 9.3 0.0 0.39 8.8 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sugar_tr PF00083.19 EMC92795.1 - 4.3e-64 216.7 10.2 4.9e-64 216.5 7.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC92795.1 - 2.5e-08 33.0 25.4 1.6e-06 27.1 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC92795.1 - 9.9e-05 20.8 8.5 9.9e-05 20.8 5.9 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein EMP70 PF02990.11 EMC92795.1 - 0.16 10.3 3.6 0.24 9.8 2.5 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Pex14_N PF04695.8 EMC92796.1 - 4.8e-39 133.5 0.1 4.8e-39 133.5 0.0 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GrpE PF01025.14 EMC92796.1 - 0.014 14.8 7.2 0.025 14.1 5.0 1.3 1 0 0 1 1 1 0 GrpE HTH_IclR PF09339.5 EMC92796.1 - 0.09 12.3 0.8 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF4208 PF13907.1 EMC92796.1 - 0.18 12.0 3.2 0.34 11.1 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Nuc_rec_co-act PF08815.5 EMC92796.1 - 0.31 10.6 2.3 1.5 8.4 0.7 2.3 2 0 0 2 2 2 0 Nuclear receptor coactivator DUF737 PF05300.6 EMC92796.1 - 5.9 6.8 18.5 0.0099 15.8 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Surp PF01805.15 EMC92797.1 - 3.6e-09 36.1 0.1 6.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Surp module Pkinase PF00069.20 EMC92798.1 - 1.5e-61 207.8 0.0 2.3e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92798.1 - 1.4e-28 99.6 0.0 2e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC92798.1 - 5.7e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC92798.1 - 0.03 13.2 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EMC92798.1 - 0.042 13.5 0.1 0.076 12.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_28 PF02636.12 EMC92799.1 - 6e-76 255.1 0.0 7.9e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Myb_DNA-bind_6 PF13921.1 EMC92799.1 - 7e-07 29.2 0.7 3.7e-06 26.9 0.1 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMC92799.1 - 0.0039 17.2 0.2 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain adh_short PF00106.20 EMC92800.1 - 5e-19 68.8 0.1 4.1e-18 65.8 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC92800.1 - 1.4e-08 34.6 0.0 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.3 EMC92800.1 - 0.053 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HAT PF02184.11 EMC92800.1 - 0.092 12.5 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat Peptidase_C12 PF01088.16 EMC92801.1 - 4.3e-53 179.6 0.0 4.8e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Complex1_LYR PF05347.10 EMC92804.1 - 0.0022 17.7 0.6 0.0031 17.2 0.1 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Herpes_UL17 PF04559.7 EMC92804.1 - 0.023 13.3 0.4 0.028 13.0 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein Complex1_LYR_1 PF13232.1 EMC92804.1 - 0.035 14.2 0.5 0.049 13.8 0.4 1.5 1 1 0 1 1 1 0 Complex1_LYR-like DnaJ PF00226.26 EMC92805.1 - 1.3e-19 69.6 0.3 1.3e-19 69.6 0.2 2.3 2 1 0 2 2 2 1 DnaJ domain SPATIAL PF15256.1 EMC92805.1 - 3.3 7.7 9.8 9.1 6.2 6.8 1.8 1 0 0 1 1 1 0 SPATIAL DUF1767 PF08585.7 EMC92806.1 - 0.12 12.6 0.0 6.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1767) RHH_1 PF01402.16 EMC92807.1 - 0.047 13.5 0.2 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Yip1 PF04893.12 EMC92808.1 - 4.1e-06 26.3 17.1 3.1e-05 23.5 11.8 2.2 1 1 0 1 1 1 1 Yip1 domain HET PF06985.6 EMC92811.1 - 2.6e-35 121.5 3.7 3e-35 121.4 2.6 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phlebovirus_G1 PF07243.6 EMC92811.1 - 0.05 11.7 0.3 0.059 11.5 0.2 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Bac_surface_Ag PF01103.18 EMC92812.1 - 5.2e-41 141.1 0.1 6.4e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Peripla_BP_2 PF01497.13 EMC92812.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Chalcone PF02431.10 EMC92812.1 - 0.11 11.9 0.2 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Glyco_hydro_1 PF00232.13 EMC92813.1 - 2.1e-105 352.5 3.5 3e-105 352.0 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 CBM_10 PF02013.11 EMC92813.1 - 0.64 10.3 2.6 1.1 9.5 0.4 2.2 2 0 0 2 2 2 0 Cellulose or protein binding domain AMP-binding PF00501.23 EMC92814.1 - 3.3e-71 239.8 0.0 5.5e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EMC92814.1 - 1.1e-63 214.4 0.0 1.8e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EMC92814.1 - 2.7e-10 40.3 0.0 5.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EMC92814.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC92814.1 - 1.7e-07 30.2 0.0 3.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EMC92814.1 - 4.2e-07 30.8 0.0 4.6e-06 27.4 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EMC92814.1 - 0.0013 18.8 0.0 0.044 13.8 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC92814.1 - 0.025 13.4 0.0 1.2 7.9 0.0 2.5 3 0 0 3 3 3 0 RmlD substrate binding domain Transketolase_C PF02780.15 EMC92814.1 - 0.098 12.5 0.0 1.4 8.8 0.0 2.4 1 1 1 2 2 2 0 Transketolase, C-terminal domain IBR PF01485.16 EMC92815.1 - 2.2e-15 56.2 45.3 2.9e-08 33.4 7.7 3.6 3 1 0 3 3 3 2 IBR domain zf-CCHC PF00098.18 EMC92815.1 - 0.018 14.9 3.5 0.018 14.9 2.5 4.3 4 0 0 4 4 4 0 Zinc knuckle zf-C3HC4_2 PF13923.1 EMC92815.1 - 0.035 14.1 6.3 0.035 14.1 4.4 4.9 4 3 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC92815.1 - 0.039 13.8 1.9 0.039 13.8 1.3 4.5 4 2 1 5 5 5 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC92815.1 - 0.26 10.8 35.7 0.046 13.3 3.0 3.9 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain Cyt-b5 PF00173.23 EMC92817.1 - 4.3e-14 52.0 0.0 5.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myotoxins PF00819.12 EMC92818.1 - 0.011 15.7 1.3 0.036 14.1 0.1 2.1 2 0 0 2 2 2 0 Myotoxin RRM_1 PF00076.17 EMC92821.1 - 9.3e-08 31.5 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC92821.1 - 1.8e-07 30.8 0.0 3.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC92821.1 - 0.00046 20.1 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC92821.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EMC92822.1 - 2.8e-30 104.0 0.3 5.4e-30 103.1 0.2 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EMC92822.1 - 1.1e-20 73.9 0.0 1.9e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC92822.1 - 9.1e-18 64.2 0.0 1.4e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC92822.1 - 8e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMC92822.1 - 1.5e-13 50.4 0.0 2.7e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EMC92822.1 - 1.5e-12 47.7 0.0 2.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC92822.1 - 3e-10 39.6 0.0 4.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMC92822.1 - 7.1e-10 39.4 0.0 2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC92822.1 - 4.5e-09 36.3 0.0 1.4e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC92822.1 - 4.9e-09 36.5 0.0 1.6e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EMC92822.1 - 1.3e-05 24.8 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 EMC92822.1 - 8.1e-05 21.1 0.0 0.00013 20.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 EMC92822.1 - 0.00023 20.4 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMC92822.1 - 0.00026 20.4 0.0 0.00081 18.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EMC92822.1 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 EMC92822.1 - 0.039 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EMC92822.1 - 0.04 13.6 0.2 0.094 12.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 EMC92822.1 - 0.047 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 EMC92822.1 - 0.051 12.6 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EMC92822.1 - 0.14 11.3 0.3 0.38 9.8 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase Pterin_4a PF01329.14 EMC92823.1 - 3.1e-26 90.9 1.5 3.8e-26 90.6 1.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase NYN PF01936.13 EMC92825.1 - 7.1e-07 29.6 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 EMC92825.1 - 0.013 15.2 0.2 3.1 7.6 0.0 2.6 3 0 0 3 3 3 0 OST-HTH/LOTUS domain Transket_pyr PF02779.19 EMC92826.1 - 3.2e-49 166.8 0.0 4.7e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMC92826.1 - 1.6e-34 118.4 0.1 5e-34 116.8 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain PsaD PF02531.11 EMC92826.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 PsaD DNA_pol_B PF00136.16 EMC92827.1 - 2.2e-114 382.8 2.4 3.3e-114 382.2 1.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EMC92827.1 - 4.2e-52 176.2 0.0 8.1e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EMC92827.1 - 1.8e-39 135.5 0.0 3.2e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EMC92827.1 - 1.4e-23 82.4 8.5 1.4e-23 82.4 5.9 3.5 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal Tnp_DNA_bind PF14706.1 EMC92827.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Transposase DNA-binding DUF427 PF04248.7 EMC92828.1 - 1.1e-27 95.5 0.1 1.4e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Oxidored_FMN PF00724.15 EMC92829.1 - 7.4e-82 275.0 0.0 8.4e-82 274.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.19 EMC92830.1 - 1.6e-14 53.3 14.2 1.1e-08 34.1 7.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter adh_short PF00106.20 EMC92833.1 - 9.8e-34 116.6 0.8 9.8e-34 116.6 0.6 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92833.1 - 1.6e-24 87.0 0.7 3.2e-24 86.0 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92833.1 - 1.3e-16 60.8 0.1 1.8e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMC92833.1 - 0.00067 19.3 0.7 0.0011 18.6 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EMC92833.1 - 0.0038 16.3 0.1 0.0065 15.5 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 EMC92833.1 - 0.0051 16.6 0.3 0.0092 15.8 0.2 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Gly_rich_SFCGS PF14272.1 EMC92833.1 - 0.015 15.1 0.5 0.038 13.8 0.4 1.7 1 0 0 1 1 1 0 Glycine-rich SFCGS UDPG_MGDP_dh_N PF03721.9 EMC92833.1 - 0.067 12.5 0.2 0.12 11.6 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Arginosuc_synth PF00764.14 EMC92834.1 - 3.8e-156 520.0 0.0 4.3e-156 519.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EMC92834.1 - 0.0003 20.3 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EMC92834.1 - 0.026 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EMC92834.1 - 0.087 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase MARVEL PF01284.18 EMC92835.1 - 0.022 14.5 9.3 0.038 13.8 6.5 1.4 1 1 0 1 1 1 0 Membrane-associating domain Ish1 PF10281.4 EMC92836.1 - 2.4e-53 177.7 21.3 3.6e-13 49.3 0.1 5.4 5 0 0 5 5 5 5 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EMC92836.1 - 1.1e-07 31.2 0.0 0.2 11.2 0.0 4.3 4 0 0 4 4 4 3 HeH/LEM domain SAP PF02037.22 EMC92836.1 - 3.7e-06 26.2 0.0 0.19 11.2 0.0 3.9 3 1 0 3 3 3 2 SAP domain Slx4 PF09494.5 EMC92836.1 - 0.00031 20.4 2.7 0.21 11.3 0.1 3.2 3 0 0 3 3 3 2 Slx4 endonuclease SpoU_methylas_C PF12105.3 EMC92836.1 - 0.0081 15.6 0.0 6.6 6.3 0.0 3.3 3 0 0 3 3 3 1 SpoU, rRNA methylase, C-terminal ING PF12998.2 EMC92836.1 - 0.35 11.1 2.1 1.3e+02 2.9 0.1 3.9 4 0 0 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding Actin PF00022.14 EMC92837.1 - 2.7e-27 95.2 0.0 3.7e-13 48.6 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EMC92837.1 - 1.8e-05 23.4 0.0 3.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein NTF2 PF02136.15 EMC92839.1 - 3.5e-30 104.7 0.4 4e-30 104.6 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EMC92839.1 - 0.071 12.8 0.1 0.12 12.0 0.1 1.4 1 1 1 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 RNA_pol_3_Rpc31 PF11705.3 EMC92840.1 - 9.2e-26 91.2 16.7 1.2e-25 90.8 11.6 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EMC92840.1 - 0.9 9.3 12.5 1 9.1 8.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 EMC92840.1 - 7.4 5.1 23.6 9.5 4.8 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tic20 PF09685.5 EMC92842.1 - 1e-05 25.4 2.9 1.5e-05 24.9 2.0 1.1 1 0 0 1 1 1 1 Tic20-like protein Epimerase PF01370.16 EMC92843.1 - 1.4e-18 67.1 0.0 2.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC92843.1 - 2.1e-10 39.9 0.0 1.7e-09 36.9 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EMC92843.1 - 3.1e-10 39.2 0.0 4.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMC92843.1 - 1.7e-07 31.4 0.1 2.6e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMC92843.1 - 4e-06 26.8 0.0 8.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMC92843.1 - 0.00055 19.2 0.1 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMC92843.1 - 0.0014 17.6 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EMC92843.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EMC92843.1 - 0.028 13.2 0.0 0.11 11.4 0.0 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 EMC92843.1 - 0.031 14.1 0.1 0.063 13.1 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMC92843.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Arf PF00025.16 EMC92844.1 - 3.8e-73 244.4 0.0 4.2e-73 244.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC92844.1 - 1.2e-11 44.1 0.0 1.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMC92844.1 - 7.3e-11 41.7 0.0 8.6e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMC92844.1 - 5e-10 38.6 0.6 2e-06 26.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMC92844.1 - 1.3e-08 34.2 0.0 1.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC92844.1 - 3e-08 34.1 0.0 4.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC92844.1 - 1.4e-05 24.9 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC92844.1 - 0.00042 19.8 0.0 0.039 13.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMC92844.1 - 0.027 13.7 0.5 0.092 12.0 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 EMC92844.1 - 0.095 13.1 0.2 0.26 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Prok-RING_4 PF14447.1 EMC92846.1 - 0.18 11.3 0.4 0.43 10.1 0.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TctB PF07331.6 EMC92848.1 - 0.061 12.9 1.8 0.1 12.2 1.3 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2892 PF11127.3 EMC92848.1 - 0.6 9.9 3.3 0.43 10.4 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2892) adh_short PF00106.20 EMC92849.1 - 4e-27 95.1 0.1 5e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92849.1 - 4e-21 75.8 0.0 4.8e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92849.1 - 3.6e-10 39.7 0.1 5.8e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC92849.1 - 3.5e-07 29.8 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMC92849.1 - 5.4e-05 22.4 0.0 7.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EMC92849.1 - 0.018 15.0 0.2 0.024 14.6 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EMC92849.1 - 0.018 14.6 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EMC92849.1 - 0.08 11.8 0.0 0.52 9.1 0.0 2.2 1 1 0 1 1 1 0 RmlD substrate binding domain FMN_dh PF01070.13 EMC92850.1 - 4.7e-120 400.6 0.0 5.8e-120 400.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMC92850.1 - 2.4e-23 81.7 0.0 4.1e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMC92850.1 - 7.5e-08 31.6 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMC92850.1 - 0.00032 19.7 0.4 0.00091 18.2 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMC92850.1 - 0.0087 15.2 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EMC92850.1 - 0.011 15.0 0.8 0.46 9.6 0.1 2.5 1 1 0 2 2 2 0 Histidine biosynthesis protein FGGY_C PF02782.11 EMC92851.1 - 8.8e-50 169.0 0.1 1.6e-49 168.2 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMC92851.1 - 2.5e-24 85.9 0.7 2.1e-20 73.0 0.0 3.0 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EMC92851.1 - 0.00014 21.2 0.0 0.0011 18.3 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Acetyltransf_3 PF13302.1 EMC92853.1 - 5e-07 29.9 0.1 5.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC92853.1 - 0.00089 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GFO_IDH_MocA PF01408.17 EMC92855.1 - 3.6e-19 69.4 0.1 5.2e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EMC92855.1 - 0.06 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EMC92855.1 - 0.11 12.8 0.2 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EMC92856.1 - 1.8e-20 73.3 0.0 2.4e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EMC92856.1 - 0.00017 20.5 0.0 0.00038 19.3 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EMC92856.1 - 0.0034 17.1 2.3 0.1 12.3 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EMC92856.1 - 0.0067 15.3 0.4 0.67 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC92856.1 - 0.096 12.7 2.5 0.24 11.4 0.4 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ADC PF06314.6 EMC92857.1 - 0.00079 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DJ-1_PfpI_N PF13587.1 EMC92857.1 - 0.27 10.8 1.2 0.52 9.8 0.2 1.9 2 1 0 2 2 2 0 N-terminal domain of DJ-1_PfpI family adh_short PF00106.20 EMC92858.1 - 1.7e-24 86.5 0.1 2.3e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92858.1 - 5.6e-21 75.3 0.0 7.5e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92858.1 - 4.9e-13 49.1 0.0 6.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 EMC92858.1 - 0.022 14.6 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EMC92858.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding Ferritin_2 PF13668.1 EMC92860.1 - 6.1e-13 48.8 0.0 9.8e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DAGK_cat PF00781.19 EMC92861.1 - 6.3e-13 48.2 0.0 1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain XPG_I_2 PF12813.2 EMC92863.1 - 1.9e-32 112.6 0.1 2.8e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing DUF1691 PF07950.6 EMC92864.1 - 7.5e-38 128.8 4.7 2.8e-22 78.7 0.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.3 EMC92865.1 - 0.00077 19.5 1.6 0.00077 19.5 1.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC92865.1 - 0.0017 18.4 2.4 0.0061 16.7 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type HMG_CoA_synt_C PF08540.5 EMC92865.1 - 0.076 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal NRDE PF05742.7 EMC92866.1 - 1.2e-46 159.2 0.0 2.4e-46 158.2 0.0 1.4 1 1 0 1 1 1 1 NRDE protein TB2_DP1_HVA22 PF03134.14 EMC92867.1 - 5.2e-25 87.0 7.3 7.3e-25 86.5 5.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4078 PF13300.1 EMC92868.1 - 3.1e-29 100.9 15.6 3.1e-29 100.9 10.8 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4078) CAF1A PF12253.3 EMC92868.1 - 0.49 10.5 7.7 1.7 8.8 5.3 2.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Homoserine_dh PF00742.14 EMC92869.1 - 2.4e-51 173.9 0.0 3.9e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EMC92869.1 - 1.7e-14 54.2 0.0 3.2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF221 PF02714.10 EMC92870.1 - 1.1e-83 280.7 12.2 2.3e-83 279.7 8.5 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMC92870.1 - 7.3e-41 139.3 2.9 2.4e-40 137.6 2.0 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMC92870.1 - 7.7e-19 68.0 3.5 1.8e-18 66.7 2.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) ScpA_ScpB PF02616.9 EMC92870.1 - 0.026 14.1 2.2 0.051 13.1 1.2 1.6 2 0 0 2 2 2 0 ScpA/B protein YMF19 PF02326.10 EMC92870.1 - 0.054 14.0 0.4 0.054 14.0 0.3 2.8 2 0 0 2 2 2 0 Plant ATP synthase F0 TMF_TATA_bd PF12325.3 EMC92870.1 - 0.23 11.2 1.8 0.46 10.2 0.1 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Lamp PF01299.12 EMC92871.1 - 1.6 7.7 5.6 7.3 5.6 3.3 2.0 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) CDC45 PF02724.9 EMC92871.1 - 2.1 6.2 6.6 3.3 5.6 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMC92871.1 - 2.7 5.7 16.7 4 5.2 11.5 1.2 1 0 0 1 1 1 0 Nop14-like family Aldo_ket_red PF00248.16 EMC92872.1 - 5.5e-57 192.7 0.0 6.4e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 EMC92873.1 - 1.3e-21 76.3 0.0 2.6e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC92873.1 - 2.2e-17 62.5 0.0 7.1e-17 60.8 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EMC92873.1 - 0.00092 19.4 0.1 0.34 11.1 0.0 2.9 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC92873.1 - 0.0073 16.7 0.3 0.085 13.2 0.0 2.5 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase AlkA_N PF06029.6 EMC92875.1 - 0.0047 16.9 0.2 0.045 13.7 0.0 2.3 2 0 0 2 2 2 1 AlkA N-terminal domain LRR_8 PF13855.1 EMC92875.1 - 0.012 15.3 10.4 0.044 13.5 3.2 2.8 2 0 0 2 2 2 0 Leucine rich repeat F-box-like PF12937.2 EMC92875.1 - 0.041 13.6 0.2 0.11 12.2 0.1 1.8 1 1 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EMC92875.1 - 5.4 6.7 13.2 8 6.2 1.0 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) IclR PF01614.13 EMC92876.1 - 0.18 11.5 2.2 0.26 10.9 1.2 1.6 1 1 0 1 1 1 0 Bacterial transcriptional regulator CUE PF02845.11 EMC92877.1 - 8.2e-12 44.3 0.0 1.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain UK PF02512.9 EMC92878.1 - 0.17 12.3 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Virulence determinant RRM_1 PF00076.17 EMC92879.1 - 1.1e-24 85.8 0.0 1.5e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC92879.1 - 8.8e-20 70.4 0.0 7.2e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC92879.1 - 2.4e-13 49.7 0.0 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ETF_QO PF05187.8 EMC92880.1 - 1.2e-45 153.9 0.0 2.1e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EMC92880.1 - 1.3e-08 34.1 0.0 0.00034 19.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC92880.1 - 4.1e-06 26.7 0.0 1.9e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC92880.1 - 5.5e-06 25.4 0.9 0.0049 15.7 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EMC92880.1 - 1.4e-05 24.3 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC92880.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC92880.1 - 0.00021 20.4 0.0 0.0059 15.7 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EMC92880.1 - 0.00032 19.3 0.3 0.00047 18.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EMC92880.1 - 0.00043 19.0 0.0 0.16 10.5 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EMC92880.1 - 0.0005 20.4 0.2 2.6 8.5 0.2 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC92880.1 - 0.00057 19.0 0.1 0.002 17.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EMC92880.1 - 0.0044 16.8 0.3 0.013 15.3 0.2 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMC92880.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EMC92880.1 - 0.0072 16.6 1.1 0.027 14.8 0.7 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 EMC92880.1 - 0.03 13.2 0.3 0.045 12.6 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EMC92880.1 - 0.086 11.6 0.2 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_23 PF13489.1 EMC92886.1 - 6.9e-17 61.6 0.0 1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC92886.1 - 3.6e-06 27.3 0.0 7.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC92886.1 - 1.7e-05 25.1 0.0 4.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC92886.1 - 8.1e-05 22.2 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC92886.1 - 0.00019 21.8 0.0 0.00074 19.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC92886.1 - 0.0017 18.8 0.0 0.0042 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC92886.1 - 0.0022 17.1 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CbiG_C PF01890.11 EMC92886.1 - 0.051 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus DAO PF01266.19 EMC92887.1 - 1.2e-50 172.4 0.4 1.4e-50 172.2 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC92887.1 - 1.1e-06 28.5 0.2 0.047 13.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMC92887.1 - 8e-06 25.7 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC92887.1 - 8.8e-05 22.4 0.0 0.48 10.2 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC92887.1 - 0.00032 19.6 0.0 0.0021 16.9 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EMC92887.1 - 0.0033 16.0 0.0 0.61 8.6 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 EMC92887.1 - 0.0046 17.0 0.0 1.4 8.9 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC92887.1 - 0.009 15.1 0.0 0.025 13.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EMC92887.1 - 0.025 14.9 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.16 EMC92888.1 - 8.1e-70 230.2 0.1 9.6e-35 117.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EMC92888.1 - 4.1e-05 23.5 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) COesterase PF00135.23 EMC92889.1 - 2.3e-68 231.2 0.6 7e-68 229.6 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC92889.1 - 2e-05 24.2 0.7 0.00015 21.3 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC92889.1 - 5.5e-05 22.4 0.1 9.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC92889.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Tagatose_6_P_K PF08013.6 EMC92890.1 - 0.045 12.1 0.1 0.059 11.8 0.0 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Not1 PF04054.10 EMC92891.1 - 9.3e-89 297.9 0.0 2.3e-88 296.6 0.0 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EMC92891.1 - 4.3e-46 156.2 2.2 9.7e-46 155.0 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) GNAT_acetyltr_2 PF13718.1 EMC92893.1 - 0.36 10.1 2.2 0.51 9.6 1.6 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CFEM PF05730.6 EMC92894.1 - 0.00013 21.7 5.4 0.00013 21.7 3.7 3.8 3 0 0 3 3 3 1 CFEM domain MFS_1 PF07690.11 EMC92895.1 - 4e-32 111.2 11.2 9.2e-17 60.7 3.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC92895.1 - 8.7e-07 27.8 12.7 4.7e-05 22.1 1.6 3.1 1 1 1 3 3 3 2 Sugar (and other) transporter Folate_carrier PF01770.13 EMC92895.1 - 0.0072 14.8 0.0 0.014 13.9 0.0 1.5 1 0 0 1 1 1 1 Reduced folate carrier DUF3007 PF11460.3 EMC92895.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) MFS_3 PF05977.8 EMC92895.1 - 0.21 9.6 11.4 0.01 13.9 0.7 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector DAHP_synth_1 PF00793.15 EMC92896.1 - 5.1e-94 313.9 0.0 6.3e-94 313.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Asp PF00026.18 EMC92896.1 - 0.034 13.4 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Got1 PF04178.7 EMC92897.1 - 3.6e-18 65.7 14.0 4.3e-18 65.5 9.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EMC92897.1 - 0.047 12.6 5.2 0.058 12.3 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Peptidase_C32 PF05411.7 EMC92897.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase DUF805 PF05656.9 EMC92897.1 - 1.6 8.5 6.8 2.1 8.1 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) ABC2_membrane_2 PF12679.2 EMC92897.1 - 2.2 7.0 6.9 2.7 6.7 4.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3353 PF11833.3 EMC92897.1 - 4.8 6.5 6.0 8.1 5.8 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Lipase_3 PF01764.20 EMC92898.1 - 1.2e-05 24.9 0.0 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EMC92898.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein VPS9 PF02204.13 EMC92899.1 - 4.1e-25 87.8 0.0 7.3e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF4054 PF13262.1 EMC92899.1 - 0.11 12.7 0.2 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Oxidored-like PF09791.4 EMC92900.1 - 6.4e-26 89.5 2.4 1e-25 88.9 1.7 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF1289 PF06945.8 EMC92900.1 - 0.34 10.4 4.4 0.62 9.5 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) AMP-binding PF00501.23 EMC92901.1 - 1e-84 284.3 0.2 1.3e-84 284.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC92901.1 - 1.6e-14 54.5 0.1 8.5e-14 52.2 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4079 PF13301.1 EMC92902.1 - 0.011 15.7 0.2 0.011 15.7 0.2 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF4079) dCMP_cyt_deam_1 PF00383.17 EMC92903.1 - 1.2e-08 34.5 0.3 6.9e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region GMC_oxred_N PF00732.14 EMC92904.1 - 2.9e-41 141.5 0.0 4.3e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC92904.1 - 6e-35 120.6 0.0 1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMC92904.1 - 7.9e-08 31.5 1.0 3e-06 26.3 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC92904.1 - 1.9e-06 27.0 7.2 0.00013 20.9 5.0 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMC92904.1 - 9.5e-06 24.7 0.0 0.0067 15.3 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMC92904.1 - 7.2e-05 22.7 1.0 0.00019 21.3 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC92904.1 - 0.00015 21.6 1.7 0.00072 19.5 1.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMC92904.1 - 0.00068 18.2 0.4 0.00096 17.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EMC92904.1 - 0.018 14.1 0.2 0.037 13.1 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EMC92904.1 - 0.039 14.0 1.3 3.1 7.8 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMC92904.1 - 0.044 12.4 0.9 0.068 11.7 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EMC92904.1 - 0.062 13.7 1.8 0.14 12.5 1.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC92904.1 - 0.067 12.0 1.2 0.11 11.3 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 EMC92904.1 - 0.069 13.1 0.9 0.13 12.2 0.6 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EMC92904.1 - 0.3 10.7 1.5 0.56 9.8 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EMC92904.1 - 1.1 8.3 3.5 1.2 8.1 1.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase TauD PF02668.11 EMC92905.1 - 2.1e-47 161.9 0.1 2.7e-47 161.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Big_4 PF07532.6 EMC92905.1 - 0.00031 20.1 0.1 0.00092 18.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 4) 2OG-FeII_Oxy_3 PF13640.1 EMC92905.1 - 0.00059 20.3 0.3 0.03 14.8 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF971 PF06155.7 EMC92905.1 - 0.0025 18.1 0.1 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.5 EMC92905.1 - 0.0049 15.8 0.0 0.047 12.5 0.0 1.9 2 0 0 2 2 2 1 CsiD DUF4531 PF15041.1 EMC92905.1 - 0.071 12.8 0.8 5.1 6.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4531) AAA PF00004.24 EMC92906.1 - 1e-39 135.7 0.0 2e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC92906.1 - 7.2e-05 22.8 0.2 0.0077 16.2 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EMC92906.1 - 0.00012 21.7 0.1 0.00059 19.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMC92906.1 - 0.00016 20.8 0.1 0.00061 18.9 0.0 1.9 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMC92906.1 - 0.00035 20.5 0.3 0.0021 17.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EMC92906.1 - 0.0015 18.7 2.0 0.021 14.9 0.0 2.9 2 1 1 3 3 2 1 AAA domain PhoH PF02562.11 EMC92906.1 - 0.0027 16.9 0.3 0.04 13.1 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EMC92906.1 - 0.005 16.0 0.1 0.017 14.3 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EMC92906.1 - 0.0065 15.4 1.0 0.013 14.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EMC92906.1 - 0.0099 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC92906.1 - 0.011 15.4 0.3 0.031 14.0 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EMC92906.1 - 0.018 14.4 2.2 0.39 10.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EMC92906.1 - 0.018 14.4 0.1 0.039 13.3 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EMC92906.1 - 0.055 13.3 0.0 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EMC92906.1 - 0.088 12.3 3.7 0.3 10.6 0.0 2.6 2 2 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EMC92906.1 - 0.16 12.8 0.1 0.16 12.8 0.1 3.1 2 2 0 2 2 2 0 AAA domain 4HBT PF03061.17 EMC92907.1 - 6.7e-10 38.9 0.0 1.6e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.1 EMC92907.1 - 0.087 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) ADH_zinc_N PF00107.21 EMC92908.1 - 0.00012 21.5 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 EMC92908.1 - 0.026 13.5 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2855 PF11017.3 EMC92908.1 - 0.045 12.8 0.5 0.059 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) ADH_N PF08240.7 EMC92908.1 - 0.064 13.0 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.14 EMC92909.1 - 7.1e-16 58.1 5.7 6.4e-13 48.4 0.2 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMC92909.1 - 1.3e-07 30.8 1.0 3.4e-05 22.9 0.6 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC92909.1 - 2.5e-05 24.2 1.3 8.1e-05 22.5 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMC92909.1 - 0.00019 21.2 1.1 0.029 14.1 0.6 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EMC92909.1 - 0.0013 17.4 3.8 0.18 10.3 0.0 2.6 2 1 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.22 EMC92909.1 - 0.039 14.3 2.3 0.092 13.1 1.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EMC92909.1 - 0.045 12.5 0.0 0.078 11.7 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase GIDA PF01134.17 EMC92909.1 - 0.051 12.4 0.9 0.094 11.5 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EMC92909.1 - 0.06 11.8 0.2 0.097 11.1 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Nup35_RRM_2 PF14605.1 EMC92909.1 - 0.14 11.9 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pyr_redox_3 PF13738.1 EMC92909.1 - 0.16 11.9 0.4 0.49 10.4 0.3 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMC92909.1 - 0.19 11.3 0.2 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EMC92909.1 - 1.2 7.9 5.7 0.84 8.4 2.1 2.0 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_11 PF00457.12 EMC92910.1 - 8e-55 185.0 15.6 8.8e-55 184.8 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 adh_short PF00106.20 EMC92912.1 - 4.6e-32 111.2 0.3 5.6e-32 110.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC92912.1 - 1.1e-23 84.3 0.0 1.3e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC92912.1 - 1e-13 51.3 0.2 1.3e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC92912.1 - 7e-08 32.1 0.1 9.1e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC92912.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EMC92912.1 - 0.014 14.4 0.1 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EMC92912.1 - 0.036 13.8 0.1 0.084 12.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMC92912.1 - 0.045 13.7 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding ABC_tran PF00005.22 EMC92913.1 - 2.3e-33 115.3 0.0 5.4e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMC92913.1 - 5.5e-20 71.9 5.1 5.5e-20 71.9 3.5 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EMC92913.1 - 1.2e-05 24.7 0.0 7.2e-05 22.1 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC92913.1 - 0.00027 20.9 0.1 0.00061 19.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EMC92913.1 - 0.00074 19.5 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMC92913.1 - 0.0023 18.0 0.2 0.017 15.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC92913.1 - 0.0035 16.4 0.2 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 EMC92913.1 - 0.0035 16.5 0.0 0.01 15.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMC92913.1 - 0.012 15.0 0.7 0.052 13.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EMC92913.1 - 0.013 14.9 0.8 0.34 10.3 0.1 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EMC92913.1 - 0.023 14.0 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMC92913.1 - 0.047 14.5 0.3 0.16 12.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMC92913.1 - 0.12 12.3 1.2 0.52 10.2 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EMC92913.1 - 0.12 12.6 0.1 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Glyco_tranf_2_3 PF13641.1 EMC92914.1 - 5.2e-19 68.9 0.1 8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC92914.1 - 3.7e-12 46.2 0.0 7.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMC92914.1 - 3.4e-10 39.4 0.0 1.9e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EMC92914.1 - 1.6e-05 24.6 3.8 2.7e-05 23.9 2.6 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_64 PF09258.5 EMC92914.1 - 0.0014 17.8 0.2 0.0027 16.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DUF1324 PF07038.6 EMC92914.1 - 0.12 12.4 0.9 0.28 11.2 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) GalKase_gal_bdg PF10509.4 EMC92915.1 - 1.7e-20 72.0 0.0 3.1e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EMC92915.1 - 4.7e-14 52.1 3.0 6.8e-14 51.6 1.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMC92915.1 - 4.2e-13 49.3 0.0 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal MttA_Hcf106 PF02416.11 EMC92915.1 - 0.0038 16.3 0.0 0.016 14.3 0.0 2.1 1 0 0 1 1 1 1 mttA/Hcf106 family Cytomega_TRL10 PF06084.6 EMC92917.1 - 0.15 11.8 2.9 0.19 11.5 2.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Pkinase PF00069.20 EMC92918.1 - 2e-15 56.6 0.0 5.4e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92918.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase FA_hydroxylase PF04116.8 EMC92919.1 - 9.6e-17 61.4 18.4 9.6e-17 61.4 12.7 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily NCA2 PF08637.5 EMC92921.1 - 9.2e-87 290.6 0.1 2.1e-86 289.4 0.0 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Ras PF00071.17 EMC92922.1 - 4.5e-66 221.2 0.1 5.4e-66 220.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC92922.1 - 6.7e-20 71.7 0.0 1.2e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC92922.1 - 1.2e-13 50.7 0.1 1.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC92922.1 - 1.1e-06 28.1 0.1 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC92922.1 - 1.6e-06 27.4 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC92922.1 - 0.0025 17.7 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC92922.1 - 0.043 13.0 0.0 0.22 10.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 EMC92922.1 - 0.045 13.9 0.0 5 7.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC92922.1 - 0.087 12.9 0.1 0.3 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EMC92922.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMA7 PF09072.5 EMC92923.1 - 8.8e-15 54.9 15.0 9.2e-15 54.8 10.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 OSTbeta PF15048.1 EMC92923.1 - 0.2 11.7 2.4 0.22 11.6 1.7 1.0 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein RNA_pol_Rpc4 PF05132.9 EMC92923.1 - 0.64 9.9 4.7 0.7 9.8 3.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 UCH PF00443.24 EMC92924.1 - 1.5e-37 129.1 0.0 2.4e-36 125.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC92924.1 - 3.7e-10 39.7 0.1 3.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase InaF-motif PF15018.1 EMC92924.1 - 0.87 9.0 2.6 2 7.9 0.3 2.2 2 0 0 2 2 2 0 TRP-interacting helix NAD_binding_10 PF13460.1 EMC92925.1 - 6.8e-20 71.8 0.0 3e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 EMC92925.1 - 0.00035 20.0 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EMC92925.1 - 0.0049 16.7 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EMC92925.1 - 0.0052 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EMC92925.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Semialdhyde_dh PF01118.19 EMC92925.1 - 0.044 14.1 0.0 0.14 12.4 0.0 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Cyclin_N PF00134.18 EMC92926.1 - 6.2e-14 51.6 1.0 2.3e-13 49.8 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EMC92926.1 - 0.44 10.4 5.8 7.4 6.4 0.8 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Ribosomal_L9_N PF01281.14 EMC92927.1 - 7.5e-09 34.7 0.0 1.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EMC92927.1 - 0.043 13.9 0.3 3.4 7.8 0.2 2.6 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain Pkinase PF00069.20 EMC92932.1 - 1.7e-57 194.5 0.0 2.1e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92932.1 - 9.9e-31 106.7 0.0 1.2e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC92932.1 - 2.1e-05 23.6 0.0 0.0001 21.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EMC92932.1 - 0.019 13.8 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EMC92932.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EMC92932.1 - 0.048 12.7 0.1 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apc4_WD40 PF12894.2 EMC92932.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.20 EMC92933.1 - 1e-51 175.5 0.0 1.5e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92933.1 - 6.4e-23 81.1 0.0 1.5e-22 79.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMC92933.1 - 0.014 14.2 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ino80_Iec3 PF14612.1 EMC92933.1 - 1.1 9.3 8.7 0.16 12.0 3.1 1.8 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Pribosyltran PF00156.22 EMC92934.1 - 5.9e-10 38.9 0.1 1.8e-09 37.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Hypoth_Ymh PF09509.5 EMC92935.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) LRR_4 PF12799.2 EMC92936.1 - 2.5e-33 113.1 33.5 2.8e-06 26.7 1.0 10.2 8 2 2 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC92936.1 - 3.6e-26 90.6 32.4 3.2e-08 33.1 0.6 9.4 3 2 8 11 11 11 9 Leucine rich repeat LRR_1 PF00560.28 EMC92936.1 - 6e-20 68.2 28.1 0.47 10.6 0.1 15.6 19 0 0 19 19 19 6 Leucine Rich Repeat LRR_7 PF13504.1 EMC92936.1 - 9.8e-14 49.0 41.4 0.7 10.3 0.0 15.5 16 0 0 16 16 16 5 Leucine rich repeat LRR_6 PF13516.1 EMC92936.1 - 4.6e-09 35.4 22.4 7.5 6.9 0.2 12.4 12 1 1 13 13 13 2 Leucine Rich repeat LRR_9 PF14580.1 EMC92936.1 - 2.7 7.4 12.0 0.88 9.1 0.1 4.4 3 1 3 6 6 6 0 Leucine-rich repeat SlyX PF04102.7 EMC92937.1 - 0.23 11.8 0.2 0.23 11.8 0.2 3.3 3 0 0 3 3 3 0 SlyX AAA_13 PF13166.1 EMC92937.1 - 2.8 6.2 8.5 0.095 11.1 1.6 1.5 2 0 0 2 2 2 0 AAA domain GRIP PF01465.15 EMC92941.1 - 9.3e-12 44.2 0.1 2.6e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 EMC92941.1 - 1.4e-06 27.7 49.8 0.004 16.3 2.8 7.4 2 2 3 7 7 7 4 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EMC92941.1 - 0.00062 19.5 0.1 0.00062 19.5 0.1 11.0 5 3 6 11 11 11 4 TPR/MLP1/MLP2-like protein Filament PF00038.16 EMC92941.1 - 0.89 8.9 186.4 0.47 9.8 5.5 8.6 3 1 2 6 6 6 0 Intermediate filament protein DUF383 PF04063.9 EMC92942.1 - 3.3e-65 219.2 0.0 1.2e-64 217.4 0.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EMC92942.1 - 1.8e-22 78.6 0.3 1.8e-22 78.6 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF384) PAP_assoc PF03828.14 EMC92943.1 - 1.2e-19 69.9 0.0 2.8e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMC92943.1 - 8.8e-05 22.7 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EMC92943.1 - 0.029 13.1 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Poly(A) polymerase central domain RRN3 PF05327.6 EMC92945.1 - 4.8 5.1 5.7 6 4.8 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-HYPF PF07503.7 EMC92946.1 - 0.059 12.8 1.3 0.11 11.9 0.9 1.5 1 0 0 1 1 1 0 HypF finger Pkinase PF00069.20 EMC92947.1 - 7.2e-71 238.3 0.0 1e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC92947.1 - 5.2e-32 110.9 0.0 7.3e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMC92947.1 - 1.2e-13 51.2 0.8 4e-13 49.6 0.5 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC92947.1 - 1.8e-08 33.7 0.1 4.3e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC92947.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family C2 PF00168.25 EMC92947.1 - 0.027 14.3 0.1 0.079 12.8 0.1 1.8 1 0 0 1 1 1 0 C2 domain Kdo PF06293.9 EMC92947.1 - 0.067 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MaoC_dehydratas PF01575.14 EMC92948.1 - 6.7e-24 83.6 0.0 1.3e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EMC92948.1 - 1.2e-08 34.8 0.0 4e-07 29.8 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase ECH PF00378.15 EMC92950.1 - 5.8e-70 235.1 0.0 7.2e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Rer1 PF03248.8 EMC92951.1 - 6.6e-77 257.0 3.9 7.6e-77 256.8 2.7 1.0 1 0 0 1 1 1 1 Rer1 family SdpI PF13630.1 EMC92951.1 - 6.3 6.5 8.3 1 9.1 1.0 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF3419 PF11899.3 EMC92952.1 - 1.1e-147 491.7 0.0 1.5e-147 491.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EMC92952.1 - 2.6e-11 43.4 0.0 2.9e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC92952.1 - 1.5e-09 38.2 0.0 3.1e-08 33.9 0.0 3.2 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC92952.1 - 3.4e-08 33.2 0.0 2e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC92952.1 - 8.2e-07 29.5 0.0 5e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC92952.1 - 8.7e-07 28.9 0.1 5.7e-05 23.1 0.0 3.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC92952.1 - 4.4e-06 27.0 0.0 0.0059 17.0 0.0 4.2 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC92952.1 - 0.00021 21.5 0.1 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC92952.1 - 0.0058 15.7 0.0 0.22 10.5 0.0 2.7 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EMC92952.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EMC92952.1 - 0.13 11.3 0.0 0.33 9.9 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase NADH_u_ox_C PF12853.2 EMC92953.1 - 3.7e-31 106.6 0.0 6e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EMC92953.1 - 1.9e-25 88.9 0.0 3.4e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Cyclin PF08613.6 EMC92954.1 - 6.3e-17 62.3 0.1 1.4e-16 61.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMC92954.1 - 4e-06 26.4 0.1 8.7e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain UFD1 PF03152.9 EMC92956.1 - 7e-26 90.4 0.0 9e-22 77.0 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 PRP21_like_P PF12230.3 EMC92956.1 - 0.028 13.9 0.1 6.9 6.0 0.0 2.7 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zinc_ribbon_5 PF13719.1 EMC92956.1 - 0.06 12.9 1.9 0.65 9.6 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMC92956.1 - 0.068 12.8 1.9 0.85 9.3 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EMC92956.1 - 5.2 6.4 8.3 1.1 8.5 0.1 3.4 3 1 0 3 3 3 0 zinc-ribbon domain CRC_subunit PF08624.5 EMC92957.1 - 7.7e-55 184.6 0.0 1.2e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit BTB PF00651.26 EMC92958.1 - 6.5e-08 32.5 0.0 2.5e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain UQ_con PF00179.21 EMC92959.1 - 8.9e-40 135.3 0.0 1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC92959.1 - 2.2e-05 24.2 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC92959.1 - 4e-05 23.4 0.0 5.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC92959.1 - 0.04 13.5 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.13 EMC92960.1 - 6e-37 127.1 0.0 2.8e-34 118.4 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain YrhK PF14145.1 EMC92962.1 - 0.0057 16.2 21.8 0.23 11.1 1.8 4.4 4 1 0 4 4 4 3 YrhK-like protein DUF2583 PF10762.4 EMC92962.1 - 8.2 6.6 7.2 1.2 9.3 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Ferric_reduct PF01794.14 EMC92964.1 - 1.7e-18 66.9 11.0 1.7e-18 66.9 7.6 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMC92964.1 - 1.2e-10 41.2 0.0 4e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EMC92964.1 - 1.1e-09 38.4 0.0 0.00012 22.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EMC92964.1 - 7e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ribosomal_L30_N PF08079.7 EMC92965.1 - 1.9e-26 91.8 20.0 4.4e-26 90.6 13.9 1.7 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EMC92965.1 - 3.2e-18 65.0 2.2 3.2e-18 65.0 1.5 2.2 2 1 1 3 3 3 1 Ribosomal protein L30p/L7e FRG1 PF06229.7 EMC92965.1 - 0.31 10.4 6.8 0.51 9.7 4.7 1.3 1 0 0 1 1 1 0 FRG1-like family adh_short_C2 PF13561.1 EMC92966.1 - 1.7e-15 57.4 0.0 4.4e-15 56.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC92966.1 - 7.7e-09 35.6 0.0 6.2e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase RINGv PF12906.2 EMC92967.1 - 6.4e-06 26.1 5.7 1.2e-05 25.2 4.0 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EMC92967.1 - 2.5e-05 24.1 3.2 4.5e-05 23.3 2.2 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EMC92967.1 - 0.00039 20.1 4.7 0.00062 19.5 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC92967.1 - 0.19 11.7 1.4 0.43 10.6 1.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 EMC92968.1 - 2.6e-72 243.1 0.1 4e-72 242.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC92968.1 - 8.9e-15 54.3 0.0 2.1e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMC92968.1 - 2e-07 30.1 0.0 4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Snapin_Pallidin PF14712.1 EMC92968.1 - 0.011 15.9 1.4 0.026 14.8 1.0 1.6 1 0 0 1 1 1 0 Snapin/Pallidin DEAD PF00270.24 EMC92968.1 - 0.021 14.3 0.0 0.24 10.8 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_11 PF13086.1 EMC92968.1 - 0.067 12.7 0.9 0.57 9.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain bZIP_2 PF07716.10 EMC92969.1 - 1.6e-06 27.7 10.2 3.6e-06 26.6 7.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC92969.1 - 3e-06 27.0 10.1 5.9e-06 26.1 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EMC92969.1 - 0.071 13.4 8.2 0.23 11.7 5.7 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor RR_TM4-6 PF06459.7 EMC92969.1 - 0.17 11.7 1.4 0.29 11.0 1.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fumble PF03630.9 EMC92972.1 - 1.6e-133 444.7 0.1 1.3e-132 441.8 0.1 1.9 1 1 0 1 1 1 1 Fumble Rtf2 PF04641.7 EMC92973.1 - 1.1e-58 198.5 0.7 1.3e-58 198.2 0.5 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EMC92973.1 - 1.5e-05 24.4 0.0 0.00069 19.0 0.0 2.5 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EMC92973.1 - 0.0012 18.4 0.1 0.0034 17.0 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMC92973.1 - 0.027 14.3 0.1 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EMC92973.1 - 0.078 12.7 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain GMC_oxred_N PF00732.14 EMC92974.1 - 4.1e-51 173.8 0.0 5.3e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC92974.1 - 2.6e-36 125.0 0.0 4e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMC92974.1 - 1.3e-06 27.6 0.0 0.0021 17.0 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC92974.1 - 1.1e-05 24.4 0.0 0.032 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMC92974.1 - 8.3e-05 22.5 0.0 0.00022 21.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMC92974.1 - 0.00015 20.8 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EMC92974.1 - 0.015 13.9 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EMC92974.1 - 0.058 12.4 0.2 0.74 8.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase MG1 PF11974.3 EMC92974.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain Aldedh PF00171.17 EMC92975.1 - 5.4e-154 512.9 0.0 6.3e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.16 EMC92977.1 - 2.2e-60 203.9 0.0 3e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNA_pol_Rpc4 PF05132.9 EMC92978.1 - 1.8 8.5 8.5 0.46 10.4 1.8 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 U79_P34 PF03064.11 EMC92978.1 - 7.6 5.9 16.4 1.8 8.0 5.5 2.4 2 0 0 2 2 2 0 HSV U79 / HCMV P34 UPF0016 PF01169.14 EMC92979.1 - 6.4e-43 144.7 25.0 7.4e-23 80.4 5.3 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3357 PF11837.3 EMC92979.1 - 0.31 10.8 7.1 0.38 10.6 0.1 4.1 3 1 2 5 5 5 0 Domain of unknown function (DUF3357) Glyco_hydro_92 PF07971.7 EMC92980.1 - 2e-147 491.8 2.6 2.6e-147 491.5 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 zf-Paramyx-P PF13008.2 EMC92981.1 - 0.024 13.8 1.1 0.035 13.2 0.8 1.3 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein F-box-like PF12937.2 EMC92982.1 - 0.0079 15.8 0.1 0.024 14.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like Seipin PF06775.9 EMC92983.1 - 3.5e-53 180.0 0.2 5e-53 179.5 0.1 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF3584 PF12128.3 EMC92985.1 - 0.0015 16.0 0.9 0.0018 15.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EMC92985.1 - 0.0075 15.4 0.7 0.01 15.0 0.5 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Cep57_CLD_2 PF14197.1 EMC92985.1 - 0.051 13.5 0.7 0.14 12.0 0.4 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Tropomyosin_1 PF12718.2 EMC92985.1 - 0.055 13.3 2.2 0.083 12.7 1.1 1.5 1 1 0 1 1 1 0 Tropomyosin like COG2 PF06148.6 EMC92985.1 - 0.069 13.0 0.6 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.5 EMC92985.1 - 0.24 11.5 1.7 0.5 10.4 1.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 EMC92985.1 - 0.66 9.8 4.5 2 8.2 1.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Na_Ca_ex PF01699.19 EMC92986.1 - 2.2e-32 111.5 25.2 1.7e-18 66.5 7.0 3.3 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EMC92986.1 - 7.4e-12 45.5 10.9 7.4e-12 45.5 7.5 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF307) TFIIF_alpha PF05793.7 EMC92986.1 - 8.1 4.6 14.5 15 3.8 9.7 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA PF00004.24 EMC92987.1 - 5.1e-44 149.6 0.0 7.9e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC92987.1 - 2.7e-08 33.6 0.0 7e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMC92987.1 - 1.1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMC92987.1 - 1.3e-06 28.5 0.0 3.2e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC92987.1 - 4.7e-06 26.7 0.1 0.00024 21.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC92987.1 - 6.5e-05 23.7 0.0 0.00014 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC92987.1 - 7.1e-05 21.9 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMC92987.1 - 0.00011 21.8 0.1 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMC92987.1 - 0.00039 19.8 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EMC92987.1 - 0.00098 17.9 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EMC92987.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC92987.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC92987.1 - 0.0021 17.2 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EMC92987.1 - 0.0026 17.3 0.0 0.0071 15.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EMC92987.1 - 0.0035 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EMC92987.1 - 0.0049 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 EMC92987.1 - 0.0068 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EMC92987.1 - 0.0083 16.4 0.0 0.027 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 EMC92987.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EMC92987.1 - 0.016 14.6 0.1 0.084 12.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMC92987.1 - 0.017 14.5 0.0 0.08 12.4 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EMC92987.1 - 0.02 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EMC92987.1 - 0.021 14.0 0.0 0.067 12.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EMC92987.1 - 0.03 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EMC92987.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EMC92987.1 - 0.05 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Histone PF00125.19 EMC92987.1 - 0.065 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NB-ARC PF00931.17 EMC92987.1 - 0.078 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EMC92987.1 - 0.087 12.4 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain PrsW-protease PF13367.1 EMC92988.1 - 8e-13 48.0 7.5 8e-13 48.0 5.2 2.0 1 1 1 2 2 2 1 Protease prsW family CMD PF02627.15 EMC92988.1 - 0.16 11.8 2.4 0.45 10.3 1.3 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family F-box-like_2 PF13013.1 EMC92989.1 - 0.059 13.0 0.3 0.23 11.1 0.2 2.1 1 1 0 1 1 1 0 F-box-like domain DUF4066 PF13278.1 EMC92990.1 - 1.4e-24 86.2 0.0 1.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMC92990.1 - 2.7e-06 26.8 0.0 7.1e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Apolipoprotein PF01442.13 EMC92991.1 - 0.0014 18.1 5.8 0.0014 18.1 4.0 2.5 2 2 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1313 PF07011.6 EMC92991.1 - 0.012 15.2 1.2 0.073 12.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1313) XH PF03469.9 EMC92991.1 - 0.017 14.8 5.4 0.16 11.6 0.1 3.7 3 2 1 4 4 4 0 XH domain ApoC-I PF04691.7 EMC92991.1 - 0.056 13.1 2.7 6 6.6 0.2 3.2 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Ground-like PF04155.13 EMC92991.1 - 0.22 11.8 3.2 0.88 9.9 0.1 3.2 3 0 0 3 3 3 0 Ground-like domain zf-RING_2 PF13639.1 EMC92993.1 - 4.8e-13 48.6 4.9 7.7e-13 48.0 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC92993.1 - 3e-07 29.9 2.6 4.8e-07 29.3 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC92993.1 - 4.6e-07 29.8 0.7 9.5e-07 28.8 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC92993.1 - 1.6e-05 24.8 4.1 2.5e-05 24.1 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC92993.1 - 2.7e-05 23.8 1.7 4.1e-05 23.2 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC92993.1 - 0.00086 18.9 1.2 0.0014 18.2 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC92993.1 - 0.0029 17.4 0.5 0.0073 16.1 0.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMC92993.1 - 0.041 13.4 2.9 0.069 12.7 2.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EMC92993.1 - 0.3 11.1 2.5 0.53 10.3 1.7 1.4 1 0 0 1 1 1 0 RING-like domain adh_short PF00106.20 EMC92994.1 - 1.9e-19 70.1 0.2 3e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC92994.1 - 8e-10 38.6 0.1 1.3e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC92994.1 - 2.3e-06 27.5 0.0 3.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC92994.1 - 6.9e-05 22.3 0.0 9.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC92994.1 - 0.00018 20.4 0.3 0.00073 18.5 0.2 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMC92994.1 - 0.011 15.6 0.1 0.037 14.0 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding BTB PF00651.26 EMC92995.1 - 0.029 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain PRMT5 PF05185.11 EMC92996.1 - 4.6e-06 25.8 0.0 1e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MFS_1 PF07690.11 EMC92997.1 - 8.7e-25 87.1 23.6 8.7e-25 87.1 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC92997.1 - 2.4e-12 46.1 9.0 2.4e-12 46.1 6.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Ras PF00071.17 EMC92998.1 - 2.4e-40 137.5 0.0 1.1e-37 128.9 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EMC92998.1 - 2e-16 60.5 0.0 3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC92998.1 - 2.6e-11 43.0 0.0 4.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC92998.1 - 0.00062 18.9 0.0 0.00085 18.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC92998.1 - 0.0017 18.2 0.0 0.004 17.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC92998.1 - 0.0026 17.9 0.0 0.0063 16.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EMC92998.1 - 0.0047 16.5 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC92998.1 - 0.017 15.0 0.2 0.043 13.7 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EMC92998.1 - 0.034 13.3 0.0 0.078 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EMC92998.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EMC92998.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 EMC92998.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.22 EMC92998.1 - 0.13 11.7 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain YrzO PF14142.1 EMC92999.1 - 0.06 12.9 0.3 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 YrzO-like protein Terminase_GpA PF05876.7 EMC92999.1 - 0.065 11.5 0.9 0.11 10.8 0.7 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF4603 PF15376.1 EMC92999.1 - 0.08 10.1 0.2 0.099 9.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) AXE1 PF05448.7 EMC93000.1 - 0.024 13.1 0.0 0.029 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) bZIP_1 PF00170.16 EMC93002.1 - 1.2e-08 34.8 12.8 4.5e-08 32.9 8.9 1.9 1 1 0 1 1 1 1 bZIP transcription factor Adeno_PIX PF03955.9 EMC93002.1 - 0.0088 16.5 0.9 0.019 15.4 0.1 1.8 2 0 0 2 2 2 1 Adenovirus hexon-associated protein (IX) DUF501 PF04417.7 EMC93002.1 - 0.024 14.5 0.3 0.043 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF3158 PF11358.3 EMC93002.1 - 0.029 13.8 0.1 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) HALZ PF02183.13 EMC93002.1 - 0.12 12.0 2.6 0.22 11.2 1.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 EMC93002.1 - 1.1 9.0 15.8 46 3.9 11.0 2.4 1 1 0 1 1 1 0 Basic region leucine zipper Fungal_trans PF04082.13 EMC93006.1 - 1.7e-15 56.6 0.0 2.5e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93006.1 - 4.8e-08 32.7 11.2 7.5e-08 32.1 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFA PF04828.9 EMC93007.1 - 4.6e-21 74.5 7.8 3.3e-11 42.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme PAP_assoc PF03828.14 EMC93008.1 - 1.4e-09 37.7 0.0 3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMC93008.1 - 6.9e-08 32.7 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Metallophos PF00149.23 EMC93010.1 - 9.5e-11 41.4 4.9 1.5e-10 40.7 3.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ERF PF04404.7 EMC93010.1 - 0.025 14.0 0.1 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 ERF superfamily Metallophos_2 PF12850.2 EMC93010.1 - 0.036 13.9 2.6 0.075 12.8 1.8 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain eIF-3c_N PF05470.7 EMC93011.1 - 3.5e-165 550.4 23.2 1.2e-136 456.3 2.6 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EMC93011.1 - 7.2e-15 55.1 1.2 3.2e-14 53.1 0.0 2.9 3 0 0 3 3 3 1 PCI domain CDC45 PF02724.9 EMC93011.1 - 0.082 10.9 15.3 0.12 10.3 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4363 PF14276.1 EMC93011.1 - 0.26 10.9 2.9 5.8 6.6 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) Caprin-1_C PF12287.3 EMC93011.1 - 2.3 7.4 5.3 4.5 6.5 3.6 1.4 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Daxx PF03344.10 EMC93011.1 - 2.6 6.3 20.3 4.5 5.6 14.1 1.3 1 0 0 1 1 1 0 Daxx Family IBR PF01485.16 EMC93012.1 - 2.2e-12 46.6 41.0 6.8e-08 32.2 4.3 3.6 3 0 0 3 3 3 2 IBR domain RRM_1 PF00076.17 EMC93012.1 - 0.065 12.8 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1543 PF07566.7 EMC93012.1 - 0.067 12.7 0.1 0.21 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) Gryzun PF07919.7 EMC93012.1 - 0.11 10.8 0.3 0.21 9.8 0.1 1.5 2 0 0 2 2 2 0 Gryzun, putative trafficking through Golgi Na_Ca_ex PF01699.19 EMC93014.1 - 1.9e-37 127.9 38.8 4.5e-19 68.4 12.3 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SURF6 PF04935.7 EMC93014.1 - 0.55 9.4 18.6 0.015 14.6 8.5 1.6 2 0 0 2 2 2 0 Surfeit locus protein 6 Actin PF00022.14 EMC93015.1 - 1.1e-24 86.5 0.0 2.1e-19 69.2 0.0 3.3 4 0 0 4 4 4 2 Actin MreB_Mbl PF06723.8 EMC93015.1 - 0.012 14.2 0.0 3.6 6.0 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Amidohydro_1 PF01979.15 EMC93016.1 - 9.2e-40 137.2 0.1 1.2e-39 136.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMC93016.1 - 3.1e-08 33.2 1.1 9.1e-08 31.7 0.1 2.2 2 2 1 3 3 3 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC93016.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase A_deaminase PF00962.17 EMC93016.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Toxin_29 PF08116.6 EMC93016.1 - 0.067 12.9 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 PhTx neurotoxin family tRNA_int_endo_N PF02778.9 EMC93016.1 - 0.087 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain ATP_sub_h PF10775.4 EMC93018.1 - 6.5e-26 89.8 1.6 9.3e-26 89.3 1.1 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EMC93018.1 - 0.0029 17.4 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 Hormone_3 PF00159.13 EMC93018.1 - 0.49 10.4 6.4 0.15 12.0 2.1 1.9 2 0 0 2 2 2 0 Pancreatic hormone peptide TFIIB PF00382.14 EMC93019.1 - 1.2e-36 124.3 0.0 1.5e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EMC93019.1 - 5.7e-12 44.7 0.2 9.6e-12 44.0 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_5 PF01022.15 EMC93019.1 - 0.00071 19.1 0.0 0.12 12.0 0.0 2.9 3 0 0 3 3 3 2 Bacterial regulatory protein, arsR family His_Phos_2 PF00328.17 EMC93021.1 - 2.3e-115 385.6 1.2 3.1e-115 385.2 0.8 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EMC93021.1 - 7.7e-07 28.7 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Acyl-CoA_dh_1 PF00441.19 EMC93022.1 - 6.5e-34 117.1 0.6 1.2e-33 116.3 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EMC93022.1 - 6.3e-18 64.3 0.1 2.6e-17 62.3 0.0 2.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EMC93022.1 - 3.5e-17 61.6 0.3 8.7e-17 60.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMC93022.1 - 3.8e-07 30.6 0.5 1.2e-06 29.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMC93022.1 - 9.2e-06 25.9 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Metallophos PF00149.23 EMC93025.1 - 2.5e-09 36.7 6.0 2.1e-08 33.8 4.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC93025.1 - 1.8e-07 31.0 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Anoctamin PF04547.7 EMC93026.1 - 4.8e-114 381.4 0.6 5.8e-114 381.2 0.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel adh_short PF00106.20 EMC93027.1 - 1e-13 51.5 0.8 1.5e-13 51.0 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC93027.1 - 1.6e-08 34.6 0.1 1.9e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC93027.1 - 2e-05 24.1 0.3 0.065 12.6 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.5 EMC93027.1 - 0.0046 16.6 0.5 0.011 15.3 0.3 1.5 1 1 1 2 2 2 1 KR domain His_biosynth PF00977.16 EMC93027.1 - 0.031 13.5 0.0 1.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Histidine biosynthesis protein BTB PF00651.26 EMC93028.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Cyclase PF04199.8 EMC93029.1 - 5.4e-12 45.7 0.0 7.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DSHCT PF08148.7 EMC93030.1 - 3.1e-59 199.2 0.2 6.5e-59 198.1 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EMC93030.1 - 7.3e-20 71.1 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC93030.1 - 1.3e-06 28.1 0.0 4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EMC93030.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 EMC93030.1 - 0.014 15.2 0.2 0.46 10.2 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PRKCSH-like PF12999.2 EMC93032.1 - 6.9e-43 146.2 6.2 2e-23 82.8 0.2 3.1 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EMC93032.1 - 8.9e-34 116.1 0.4 2.3e-33 114.8 0.1 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EMC93032.1 - 1.9e-11 44.6 0.1 7e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Herpes_UL6 PF01763.11 EMC93032.1 - 0.16 10.0 0.4 0.22 9.6 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3584 PF12128.3 EMC93032.1 - 0.24 8.6 6.4 0.37 8.0 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF745 PF05335.8 EMC93032.1 - 2.4 7.6 4.6 1.9 7.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Cortex-I_coil PF09304.5 EMC93032.1 - 5.4 7.1 15.8 3.3 7.8 3.0 2.6 2 1 1 3 3 3 0 Cortexillin I, coiled coil Prefoldin_2 PF01920.15 EMC93032.1 - 8.6 6.1 8.5 7 6.4 0.7 3.0 3 0 0 3 3 3 0 Prefoldin subunit Acetyltransf_3 PF13302.1 EMC93033.1 - 0.028 14.5 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4463 PF14703.1 EMC93034.1 - 0.12 12.9 0.0 0.43 11.1 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) Peptidase_S10 PF00450.17 EMC93035.1 - 2.8e-83 280.3 0.3 5e-83 279.5 0.2 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMC93035.1 - 0.009 15.9 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L50 PF10501.4 EMC93038.1 - 3.8e-14 52.6 0.0 6.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S DUF4267 PF14087.1 EMC93039.1 - 0.02 14.4 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) DUF4260 PF14079.1 EMC93039.1 - 0.068 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) DUF974 PF06159.8 EMC93039.1 - 0.55 9.6 4.0 1 8.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF974) ChAPs PF09295.5 EMC93042.1 - 6.3e-154 512.5 0.0 7.9e-154 512.1 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EMC93042.1 - 1.8e-05 24.3 0.0 3.3 7.4 0.0 3.5 3 0 0 3 3 3 3 TPR repeat TPR_19 PF14559.1 EMC93042.1 - 6.5e-05 23.2 1.6 0.053 13.8 0.0 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC93042.1 - 0.00046 20.5 1.6 7.7 7.4 0.1 4.9 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC93042.1 - 0.00056 20.5 0.0 17 6.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC93042.1 - 0.00071 19.2 1.7 12 6.0 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF605 PF04652.11 EMC93042.1 - 0.79 9.0 12.8 1.2 8.4 8.9 1.2 1 0 0 1 1 1 0 Vta1 like TPR_11 PF13414.1 EMC93043.1 - 0.00017 21.1 3.9 2.3 7.9 0.0 5.0 4 1 0 4 4 4 3 TPR repeat TPR_14 PF13428.1 EMC93043.1 - 1.3 9.8 7.0 30 5.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Stn1 PF10451.4 EMC93044.1 - 1.5 7.5 6.2 2 7.2 4.3 1.1 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DUF3292 PF11696.3 EMC93045.1 - 2.6e-233 775.6 0.0 3e-233 775.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Profilin PF00235.14 EMC93045.1 - 2.6e-35 121.1 0.0 6.7e-35 119.8 0.0 1.7 1 0 0 1 1 1 1 Profilin RRM_1 PF00076.17 EMC93046.1 - 1.7e-13 49.9 0.0 1.8e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC93046.1 - 6.3e-11 42.0 0.0 6.8e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC93046.1 - 1.6e-06 27.8 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_like PF13242.1 EMC93048.1 - 8.3e-09 35.0 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EMC93048.1 - 4.7e-07 30.1 0.0 1.5e-05 25.2 0.0 2.2 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF676 PF05057.9 EMC93049.1 - 5e-40 137.1 0.0 5.8e-26 91.1 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EMC93049.1 - 0.049 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Acyl_transf_1 PF00698.16 EMC93050.1 - 5.7e-80 269.0 0.0 3.3e-78 263.2 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EMC93050.1 - 8.9e-39 131.6 0.0 2.5e-38 130.2 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EMC93050.1 - 1.1e-30 105.1 0.4 7.4e-30 102.5 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EMC93050.1 - 1.9e-22 79.4 0.1 8.4e-22 77.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EMC93050.1 - 8.4e-05 21.8 0.2 0.00048 19.3 0.1 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase Phi-29_GP3 PF05435.6 EMC93050.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 PTPS PF01242.14 EMC93050.1 - 0.1 12.2 0.1 0.44 10.2 0.0 2.1 3 0 0 3 3 3 0 6-pyruvoyl tetrahydropterin synthase ketoacyl-synt PF00109.21 EMC93051.1 - 6.6e-20 71.6 0.0 1.4e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EMC93051.1 - 1.2e-18 67.7 0.0 2.1e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EMC93051.1 - 2.4e-16 59.5 0.0 5.6e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EMC93051.1 - 2.1e-10 40.4 0.0 7e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EMC93051.1 - 2.8e-07 30.6 0.0 6.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93051.1 - 0.0019 17.8 0.0 0.0061 16.2 0.0 1.8 1 0 0 1 1 1 1 KR domain Bac_rhamnosid PF05592.6 EMC93052.1 - 1.6e-22 79.3 0.0 1.5e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EMC93052.1 - 0.00066 18.4 0.2 0.00097 17.8 0.2 1.1 1 0 0 1 1 1 1 Trehalase DUF1737 PF08410.5 EMC93052.1 - 0.01 15.6 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) RCC1 PF00415.13 EMC93053.1 - 3e-57 190.6 0.4 1.7e-09 37.7 0.0 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC93053.1 - 1.4e-30 104.2 34.3 6.2e-08 32.0 1.1 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EMC93053.1 - 0.14 11.6 1.0 2 7.9 0.0 2.8 2 0 0 2 2 2 0 Putative carbohydrate binding domain Bd3614_N PF14442.1 EMC93053.1 - 6.3 6.7 8.6 0.2 11.6 1.6 1.7 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal MFS_1 PF07690.11 EMC93054.1 - 2.7e-20 72.3 84.4 5.7e-18 64.7 34.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 EMC93057.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC93057.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2524 PF10732.4 EMC93058.1 - 0.0038 17.3 0.6 0.016 15.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2524) DUF2894 PF11445.3 EMC93058.1 - 0.016 15.5 1.3 0.033 14.4 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) MobA_MobL PF03389.10 EMC93058.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 MobA/MobL family Nic96 PF04097.9 EMC93060.1 - 6.4e-175 582.7 0.1 1.2e-174 581.8 0.0 1.4 2 0 0 2 2 2 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EMC93060.1 - 8.8e-14 51.7 88.7 3.5e-08 33.6 25.2 3.5 2 1 1 3 3 3 2 Nucleoporin FG repeat region Amidase PF01425.16 EMC93063.1 - 4.4e-113 378.4 0.6 5.3e-113 378.1 0.4 1.0 1 0 0 1 1 1 1 Amidase DUF2360 PF10152.4 EMC93064.1 - 6.5 7.0 6.5 7.7 6.7 4.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Y_phosphatase PF00102.22 EMC93065.1 - 1.5e-55 188.1 0.2 1.1e-52 178.7 0.1 3.3 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EMC93065.1 - 5e-11 42.9 0.0 1.6e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EMC93065.1 - 0.011 15.2 0.2 0.029 13.9 0.2 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC93065.1 - 0.017 15.3 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family TB PF00683.12 EMC93066.1 - 6.2 6.4 7.3 3.4 7.3 1.5 2.2 2 0 0 2 2 2 0 TB domain TPR_19 PF14559.1 EMC93067.1 - 9.7e-11 41.8 0.6 4.1e-05 23.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC93067.1 - 1.1e-05 25.2 4.2 0.00067 19.5 0.3 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC93067.1 - 1.9e-05 24.2 0.7 0.0018 17.8 0.1 3.1 2 2 1 3 3 3 2 TPR repeat TPR_14 PF13428.1 EMC93067.1 - 9.6e-05 22.6 8.4 0.16 12.7 0.0 5.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC93067.1 - 0.00012 22.2 0.1 0.71 10.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC93067.1 - 0.00037 21.0 7.2 0.0052 17.4 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC93067.1 - 0.00088 19.0 0.1 2.4 8.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMC93067.1 - 0.05 14.0 2.0 67 4.3 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC93067.1 - 0.15 12.0 3.7 0.21 11.5 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC93067.1 - 0.23 11.7 1.0 9.2 6.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.13 EMC93068.1 - 6.7e-58 194.9 0.1 1.9e-57 193.5 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMC93068.1 - 1.2e-46 158.0 0.3 1.7e-44 151.1 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMC93068.1 - 1.3e-38 131.8 0.6 6.4e-38 129.6 0.1 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EMC93068.1 - 0.0051 16.3 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Ustilago_mating PF05722.7 EMC93070.1 - 0.033 13.5 1.0 0.038 13.2 0.7 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Methyltransf_6 PF03737.10 EMC93072.1 - 1.5e-28 99.6 0.0 1.9e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase DUF2296 PF10058.4 EMC93073.1 - 2.3e-20 72.0 0.3 4.2e-20 71.2 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF4463 PF14703.1 EMC93073.1 - 0.0075 16.7 0.0 0.023 15.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Cep57_CLD_2 PF14197.1 EMC93073.1 - 0.094 12.6 0.1 0.094 12.6 0.0 2.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF336 PF03928.9 EMC93074.1 - 2.1e-32 111.6 0.4 2.6e-32 111.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) GAF_2 PF13185.1 EMC93074.1 - 0.13 12.6 0.1 0.18 12.2 0.1 1.4 1 1 0 1 1 1 0 GAF domain HET PF06985.6 EMC93075.1 - 7.9e-22 77.9 0.0 1.6e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_97 PF10566.4 EMC93076.1 - 3e-57 193.7 0.0 4e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 GH97_N PF14508.1 EMC93076.1 - 1.5e-33 115.8 0.0 2.3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase 97 N-terminal GH97_C PF14509.1 EMC93076.1 - 1.7e-09 37.6 0.0 2.4e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyl-hydrolase 97 C-terminal, oligomerisation DASH_Duo1 PF08651.5 EMC93078.1 - 1.4e-27 95.0 2.2 2.6e-27 94.2 1.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.8 EMC93078.1 - 0.024 14.1 8.4 0.019 14.4 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF1366 PF07104.6 EMC93078.1 - 0.24 11.0 0.1 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) DASH_Dad2 PF08654.5 EMC93078.1 - 0.24 11.3 7.8 8 6.5 5.4 2.3 1 1 0 1 1 1 0 DASH complex subunit Dad2 Radial_spoke_3 PF06098.6 EMC93078.1 - 0.78 8.6 13.8 0.13 11.2 5.1 2.0 2 0 0 2 2 2 0 Radial spoke protein 3 Macoilin PF09726.4 EMC93078.1 - 0.82 7.8 13.7 1 7.5 9.5 1.1 1 0 0 1 1 1 0 Transmembrane protein rRNA_processing PF08524.6 EMC93078.1 - 1.7 8.3 13.2 1.6 8.5 0.5 2.1 2 0 0 2 2 2 0 rRNA processing Dermcidin PF15291.1 EMC93079.1 - 0.006 16.7 0.5 0.007 16.5 0.3 1.1 1 0 0 1 1 1 1 Dermcidin, antibiotic peptide MFS_1 PF07690.11 EMC93083.1 - 1.1e-27 96.6 28.7 1.1e-27 96.6 19.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxysterol_BP PF01237.13 EMC93084.1 - 7.9e-90 300.8 0.7 9.5e-90 300.6 0.5 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2778 PF10908.3 EMC93085.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) DUF3445 PF11927.3 EMC93086.1 - 2.1e-81 272.9 0.0 2.4e-80 269.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) Cellulase-like PF12876.2 EMC93086.1 - 0.077 13.4 0.0 0.23 11.9 0.0 1.8 1 1 0 1 1 1 0 Sugar-binding cellulase-like Aminotran_5 PF00266.14 EMC93087.1 - 1.5e-20 73.2 0.0 2.1e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMC93087.1 - 0.011 14.8 0.3 0.084 11.8 0.2 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EMC93087.1 - 0.011 14.0 0.0 0.025 12.8 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF480 PF04337.7 EMC93088.1 - 0.036 13.9 5.3 3 7.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF480 UBN2 PF14223.1 EMC93088.1 - 0.28 10.9 2.8 0.47 10.2 1.6 1.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type MRP-S26 PF14943.1 EMC93088.1 - 0.36 10.3 7.9 0.63 9.5 5.5 1.3 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 Caldesmon PF02029.10 EMC93088.1 - 0.38 9.1 5.9 0.51 8.7 4.1 1.1 1 0 0 1 1 1 0 Caldesmon Activator_LAG-3 PF11498.3 EMC93088.1 - 0.62 8.7 21.6 0.84 8.3 15.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 APC_CDC26 PF10471.4 EMC93088.1 - 2.5 8.8 15.7 0.36 11.5 7.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Snf7 PF03357.16 EMC93089.1 - 3e-20 72.3 13.9 3.5e-20 72.0 9.6 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EMC93089.1 - 0.079 12.3 2.9 0.15 11.4 2.0 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Cytochrom_B562 PF07361.6 EMC93089.1 - 0.51 10.7 10.0 0.12 12.7 2.5 2.4 2 1 0 2 2 2 0 Cytochrome b562 Spore_III_AF PF09581.5 EMC93089.1 - 0.87 9.4 6.3 1.4 8.7 4.4 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Prominin PF05478.6 EMC93089.1 - 1.9 5.9 5.5 2.2 5.6 3.8 1.2 1 0 0 1 1 1 0 Prominin DUF4355 PF14265.1 EMC93089.1 - 4.2 7.3 14.4 1 9.3 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) TPR_MLP1_2 PF07926.7 EMC93089.1 - 5.8 6.6 10.9 2.3 7.9 3.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SLAC1 PF03595.12 EMC93090.1 - 1.2e-79 267.3 47.4 1.4e-79 267.1 32.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Brix PF04427.13 EMC93091.1 - 6.4e-50 169.4 0.0 8.1e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.8 EMC93091.1 - 0.0091 15.9 5.8 0.012 15.5 4.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 EMC93091.1 - 3.2 6.1 24.8 5.9 5.2 17.2 1.4 1 0 0 1 1 1 0 Daxx Family DEAD PF00270.24 EMC93092.1 - 2.9e-45 153.7 0.0 4.5e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC93092.1 - 1.8e-27 95.0 0.0 3.6e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC93092.1 - 0.0011 18.8 0.0 0.0048 16.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HET PF06985.6 EMC93094.1 - 1e-16 61.3 0.0 1.4e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GDC-P PF02347.11 EMC93095.1 - 3.5e-180 599.2 0.0 1.4e-164 547.8 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EMC93095.1 - 5.1e-09 35.6 0.7 1.3e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Beta-eliminating lyase Glyco_hydro_65m PF03632.10 EMC93096.1 - 4e-73 246.2 0.1 1.4e-71 241.1 0.0 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EMC93096.1 - 1.9e-38 132.2 0.0 4.4e-38 131.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EMC93096.1 - 1.9e-05 24.6 0.1 4.6e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.20 EMC93096.1 - 0.00073 19.3 0.5 0.0025 17.6 0.4 1.9 1 0 0 1 1 1 1 F5/8 type C domain FAD_binding_3 PF01494.14 EMC93097.1 - 9.7e-27 93.9 0.1 1.5e-26 93.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC93097.1 - 5.9e-10 38.5 8.2 3.6e-05 22.8 2.0 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMC93097.1 - 1.1e-08 34.1 0.6 0.039 12.5 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase HI0933_like PF03486.9 EMC93097.1 - 8e-07 27.8 3.7 0.0019 16.7 1.4 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EMC93097.1 - 2.6e-06 27.3 0.3 7.5e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC93097.1 - 4.4e-06 25.8 6.6 5.2e-06 25.5 1.5 2.5 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC93097.1 - 5.6e-06 26.3 0.7 1.3e-05 25.2 0.5 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC93097.1 - 0.00036 20.8 1.6 0.056 13.8 0.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC93097.1 - 0.0016 18.5 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC93097.1 - 0.0055 15.6 1.1 0.0092 14.8 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 EMC93097.1 - 0.0072 15.4 0.2 0.57 9.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EMC93097.1 - 0.0081 15.7 0.2 0.016 14.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EMC93097.1 - 0.013 14.6 0.5 0.028 13.5 0.3 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EMC93097.1 - 0.018 13.9 1.4 0.22 10.4 1.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EMC93097.1 - 0.041 13.3 0.6 0.094 12.1 0.4 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Toxin_62 PF15540.1 EMC93097.1 - 0.062 13.4 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 62 cNMP_binding PF00027.24 EMC93099.1 - 3.9e-38 129.1 0.0 5.1e-20 71.0 0.0 4.4 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EMC93099.1 - 1.2e-17 64.5 6.0 6.6e-17 62.1 2.9 2.8 2 1 0 2 2 2 1 Patatin-like phospholipase Paf1 PF03985.8 EMC93100.1 - 5e-44 150.7 0.3 1.5e-30 106.3 0.0 2.7 2 1 0 2 2 2 2 Paf1 ATP_sub_h PF10775.4 EMC93100.1 - 0.0094 15.6 1.1 0.039 13.6 0.1 2.3 2 0 0 2 2 2 1 ATP synthase complex subunit h zf-primase PF09329.6 EMC93101.1 - 3.3e-15 55.3 0.3 6e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Primase zinc finger Cwf_Cwc_15 PF04889.7 EMC93101.1 - 0.0041 16.8 0.5 0.0041 16.8 0.4 2.0 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein TMEM247 PF15444.1 EMC93101.1 - 0.045 13.5 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 RNase_H2-Ydr279 PF09468.5 EMC93102.1 - 6.1e-64 216.1 0.0 7.4e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) TTL PF03133.10 EMC93103.1 - 8.3e-56 189.0 0.0 1.1e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EMC93103.1 - 1.8e-05 24.5 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EMC93103.1 - 3.5e-05 22.7 0.0 0.00057 18.7 0.0 2.3 2 1 0 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 EMC93103.1 - 0.075 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Actin PF00022.14 EMC93104.1 - 3.3e-91 305.6 0.0 4.4e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Actin PPR_2 PF13041.1 EMC93107.1 - 1.6e-19 69.6 0.4 1.2e-14 53.9 0.0 4.9 4 1 1 5 5 5 1 PPR repeat family PPR PF01535.15 EMC93107.1 - 1.7e-07 30.7 0.5 3.8e-05 23.3 0.0 4.2 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 EMC93107.1 - 2.5e-05 23.6 0.0 0.0017 17.7 0.0 3.5 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.1 EMC93107.1 - 3.3e-05 23.8 0.1 0.87 10.0 0.0 4.8 5 0 0 5 5 5 1 Pentatricopeptide repeat domain SLBP_RNA_bind PF15247.1 EMC93107.1 - 0.079 12.7 0.0 3.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Kinesin PF00225.18 EMC93108.1 - 2.6e-61 207.1 0.0 3.5e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF1311 PF07007.7 EMC93108.1 - 0.12 12.4 7.2 0.31 11.1 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) AAA_33 PF13671.1 EMC93108.1 - 0.37 10.6 3.1 0.56 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain HAP1_N PF04849.8 EMC93108.1 - 1.5 7.7 14.0 27 3.5 9.8 2.1 1 1 0 1 1 1 0 HAP1 N-terminal conserved region UL73_N PF12522.3 EMC93109.1 - 0.27 10.8 5.1 0.45 10.1 3.5 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal I_LWEQ PF01608.12 EMC93110.1 - 0.0043 17.0 1.3 0.0056 16.6 0.9 1.2 1 0 0 1 1 1 1 I/LWEQ domain alpha-hel2 PF14456.1 EMC93110.1 - 0.025 13.3 1.1 0.031 13.0 0.7 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 Ribosomal_L50 PF10501.4 EMC93110.1 - 0.075 13.0 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S DUF802 PF05650.6 EMC93110.1 - 0.082 13.0 0.2 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF802) OEP PF02321.13 EMC93110.1 - 0.54 9.8 4.1 0.72 9.4 2.8 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein DUF465 PF04325.8 EMC93110.1 - 3.7 7.3 9.7 1.5 8.5 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF465) AAA_12 PF13087.1 EMC93114.1 - 4.1e-07 29.5 0.0 5.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC93115.1 - 8.6e-06 25.4 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMC93115.1 - 0.00016 21.3 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMC93115.1 - 0.00028 20.5 0.0 0.00038 20.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EMC93115.1 - 0.0003 20.4 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 Helicase FtsK_SpoIIIE PF01580.13 EMC93115.1 - 0.045 13.2 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family BRK PF07533.11 EMC93115.1 - 0.062 12.7 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 BRK domain TENA_THI-4 PF03070.11 EMC93117.1 - 0.067 12.9 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family SHS2_Rpb7-N PF03876.12 EMC93119.1 - 6e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EMC93119.1 - 1.3e-08 34.7 0.1 1.9e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EMC93119.1 - 0.0026 17.9 0.0 0.029 14.5 0.0 2.4 2 1 1 3 3 3 1 RNA polymerase III subunit Rpc25 DUF605 PF04652.11 EMC93121.1 - 0.014 14.8 18.8 0.017 14.5 13.0 1.1 1 0 0 1 1 1 0 Vta1 like IncA PF04156.9 EMC93121.1 - 0.13 11.8 0.1 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 IncA protein TFIIA PF03153.8 EMC93121.1 - 1.1 9.0 4.4 1.3 8.8 3.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_UL95 PF03038.9 EMC93126.1 - 0.28 10.0 1.5 0.38 9.5 1.1 1.3 1 0 0 1 1 1 0 UL95 family HlyD_2 PF12700.2 EMC93126.1 - 1.6 7.8 6.9 6.8 5.7 4.8 1.9 1 1 0 1 1 1 0 HlyD family secretion protein Coiled-coil_56 PF09813.4 EMC93127.1 - 0.00034 20.5 0.0 0.00036 20.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 EMC93128.1 - 6.2e-60 202.5 0.0 8.9e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) AAA_25 PF13481.1 EMC93128.1 - 0.0099 15.2 0.0 4 6.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Methyltransf_23 PF13489.1 EMC93131.1 - 1.3e-11 44.5 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC93131.1 - 2.7e-05 24.5 0.3 0.38 11.2 0.2 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EMC93131.1 - 3.2e-05 23.5 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EMC93131.1 - 5.5e-05 23.5 0.0 0.00036 20.9 0.0 2.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC93131.1 - 0.0014 19.1 0.1 0.011 16.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC93131.1 - 0.0017 18.3 0.0 0.014 15.4 0.0 2.1 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EMC93133.1 - 4.6e-18 65.4 0.0 8.9e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC93133.1 - 7e-13 49.1 0.0 1.2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC93133.1 - 1.2e-12 47.6 0.0 1.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC93133.1 - 1.4e-10 41.1 0.0 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC93133.1 - 3.2e-10 40.2 0.0 6.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC93133.1 - 1.4e-09 38.3 0.0 2.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC93133.1 - 1.4e-07 31.5 0.0 4.2e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC93133.1 - 2e-07 30.3 0.0 3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMC93133.1 - 0.0039 16.5 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EMC93133.1 - 0.0077 15.2 0.0 0.017 14.2 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 EMC93133.1 - 0.022 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_24 PF13578.1 EMC93133.1 - 0.066 14.0 0.1 0.27 12.0 0.0 2.0 3 0 0 3 3 2 0 Methyltransferase domain PCMT PF01135.14 EMC93133.1 - 0.095 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EMC93133.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 EMC93133.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.15 EMC93133.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MULE PF10551.4 EMC93134.1 - 0.08 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 MULE transposase domain Glyco_hydro_2_N PF02837.13 EMC93135.1 - 1.2e-27 96.5 0.2 1.8e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMC93135.1 - 7.2e-12 44.8 0.0 4.2e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMC93135.1 - 3.1e-08 34.0 0.0 7.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Csm1 PF12539.3 EMC93136.1 - 4.4e-24 84.7 0.0 1.5e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Filament PF00038.16 EMC93136.1 - 0.0026 17.2 10.6 0.0056 16.1 7.3 1.5 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 EMC93136.1 - 0.019 14.5 11.6 0.023 14.2 7.2 1.7 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 EMC93136.1 - 0.14 11.9 14.0 0.054 13.3 7.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EMC93136.1 - 0.15 11.0 12.8 0.27 10.2 8.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EMC93136.1 - 0.18 10.4 15.2 1.7 7.2 10.6 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein ICAT PF06384.6 EMC93136.1 - 0.24 11.2 2.2 0.45 10.3 0.6 2.0 1 1 1 2 2 2 0 Beta-catenin-interacting protein ICAT FUSC PF04632.7 EMC93136.1 - 0.62 8.4 4.4 0.9 7.8 3.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF904 PF06005.7 EMC93136.1 - 0.64 10.3 12.4 0.1 12.9 4.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF607 PF04678.8 EMC93136.1 - 1.2 9.0 3.6 2.9 7.7 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF607 GAS PF13851.1 EMC93136.1 - 1.7 7.7 17.1 0.58 9.3 4.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 EMC93136.1 - 1.9 8.3 15.7 0.1 12.3 1.3 3.8 3 2 0 3 3 3 0 Homeobox associated leucine zipper ADIP PF11559.3 EMC93136.1 - 3 7.7 20.1 2 8.2 9.4 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Glycophorin_A PF01102.13 EMC93136.1 - 5.6 6.7 8.2 0.42 10.3 1.1 2.5 2 1 1 3 3 3 0 Glycophorin A Rootletin PF15035.1 EMC93136.1 - 5.9 6.8 14.2 93 2.9 10.1 2.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMPIT PF07851.8 EMC93136.1 - 9.5 5.1 5.5 6 5.8 2.5 1.6 1 1 0 1 1 1 0 TMPIT-like protein AIG2_2 PF13772.1 EMC93137.1 - 6.6e-06 26.1 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EMC93137.1 - 7.2e-05 23.2 0.1 0.00011 22.6 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family ChaC PF04752.7 EMC93137.1 - 0.0054 16.7 0.1 0.008 16.1 0.1 1.3 1 0 0 1 1 1 1 ChaC-like protein Abhydrolase_4 PF08386.5 EMC93137.1 - 0.051 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein IBR PF01485.16 EMC93138.1 - 0.0012 18.6 8.8 0.0012 18.6 6.1 4.5 3 3 0 3 3 3 2 IBR domain CUE PF02845.11 EMC93138.1 - 0.016 14.6 0.2 14 5.3 0.1 3.3 3 0 0 3 3 3 0 CUE domain Colicin_V PF02674.11 EMC93138.1 - 0.024 14.4 0.3 0.038 13.8 0.2 1.2 1 0 0 1 1 1 0 Colicin V production protein KH_1 PF00013.24 EMC93139.1 - 0.00048 19.7 0.0 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EMC93139.1 - 0.015 14.9 0.1 0.13 11.9 0.0 2.5 3 0 0 3 3 3 0 KH domain KH_4 PF13083.1 EMC93139.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 KH domain SMP PF04927.7 EMC93141.1 - 6.8e-13 48.3 12.3 6.5e-06 26.0 0.1 3.3 2 1 1 3 3 3 3 Seed maturation protein Peptidase_M28 PF04389.12 EMC93142.1 - 6.2e-22 78.2 0.4 1.3e-21 77.1 0.3 1.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 EMC93142.1 - 0.00054 18.8 0.0 0.0011 17.7 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 EMC93142.1 - 0.00083 18.9 0.0 0.00099 18.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PAN_4 PF14295.1 EMC93143.1 - 1.4e-06 27.8 0.4 4.1e-06 26.3 0.3 1.8 1 0 0 1 1 1 1 PAN domain DUF1191 PF06697.7 EMC93143.1 - 0.00035 19.4 0.0 0.00056 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Rifin_STEVOR PF02009.11 EMC93143.1 - 0.012 15.2 4.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Rifin/stevor family DUF456 PF04306.8 EMC93143.1 - 0.028 14.4 2.5 0.049 13.6 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Adeno_E3_CR2 PF02439.10 EMC93143.1 - 0.028 13.9 0.1 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EMC93143.1 - 0.11 12.9 0.1 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EMC93143.1 - 0.13 11.6 1.0 0.33 10.3 0.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2776 PF10951.3 EMC93143.1 - 2 7.3 9.0 0.049 12.6 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2776) Macoilin PF09726.4 EMC93143.1 - 3.7 5.7 12.9 5.5 5.1 9.0 1.2 1 0 0 1 1 1 0 Transmembrane protein PRKCSH PF07915.8 EMC93144.1 - 1.2e-15 58.0 2.1 3e-15 56.7 0.1 2.6 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EMC93144.1 - 0.0033 16.9 0.0 0.066 12.6 0.0 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein TIP41 PF04176.8 EMC93147.1 - 1.2e-69 233.2 0.1 1.6e-69 232.8 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family Med3 PF11593.3 EMC93147.1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AA_kinase PF00696.23 EMC93148.1 - 1.6e-39 135.9 1.0 2.5e-39 135.2 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EMC93148.1 - 4.6e-17 61.5 0.1 9.8e-17 60.4 0.1 1.6 1 0 0 1 1 1 1 PUA domain HET PF06985.6 EMC93150.1 - 9.7e-31 106.7 1.1 1.6e-30 106.0 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ery_res_leader1 PF08051.6 EMC93151.1 - 4.6 7.0 5.4 1.6 8.5 1.5 2.0 2 0 0 2 2 2 0 Erythromycin resistance leader peptide Sybindin PF04099.7 EMC93152.1 - 6.7e-46 155.5 0.0 8.2e-46 155.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EMC93152.1 - 3.9e-06 26.7 0.0 1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region UQ_con PF00179.21 EMC93153.1 - 3.4e-44 149.6 0.2 3.2e-29 101.1 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC93153.1 - 2.9e-06 27.0 0.0 0.00015 21.5 0.0 2.7 3 0 0 3 3 3 1 Prokaryotic E2 family B UEV PF05743.8 EMC93153.1 - 0.0032 17.1 0.0 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 UEV domain RWD PF05773.17 EMC93153.1 - 0.0065 16.3 0.0 2.1 8.2 0.0 2.6 2 1 0 2 2 2 2 RWD domain Peptidase_S8 PF00082.17 EMC93156.1 - 8.9e-40 136.6 14.6 1.4e-39 135.9 10.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMC93156.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I9 zf-C2H2_4 PF13894.1 EMC93157.1 - 0.0013 18.8 7.6 0.093 13.1 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC93157.1 - 0.02 15.1 3.4 5.3 7.5 0.3 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type FAD_binding_3 PF01494.14 EMC93159.1 - 1e-18 67.5 1.2 1.4e-17 63.7 0.8 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC93159.1 - 5.3e-11 42.0 7.0 6.4e-07 28.5 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMC93159.1 - 3.1e-07 29.4 6.7 0.023 13.3 3.1 3.1 2 1 1 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.2 EMC93159.1 - 6.4e-06 25.4 0.8 1e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC93159.1 - 5.3e-05 23.5 1.8 0.00094 19.5 0.6 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC93159.1 - 0.00011 22.1 2.9 0.00031 20.6 2.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC93159.1 - 0.00013 21.8 1.5 0.00037 20.4 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EMC93159.1 - 0.0003 19.7 0.5 0.00042 19.3 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMC93159.1 - 0.00062 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMC93159.1 - 0.00089 18.4 2.1 0.0074 15.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EMC93159.1 - 0.00092 17.7 7.7 0.025 13.0 4.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EMC93159.1 - 0.0042 16.0 2.2 0.027 13.3 1.5 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMC93159.1 - 0.0057 16.4 2.3 0.039 13.7 1.6 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 EMC93159.1 - 0.0059 15.7 2.1 0.0095 15.0 1.5 1.3 1 0 0 1 1 1 1 Thi4 family Rossmann-like PF10727.4 EMC93159.1 - 0.0068 16.1 0.4 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Rossmann-like domain FAD_binding_2 PF00890.19 EMC93159.1 - 0.21 10.3 10.6 0.12 11.1 5.8 1.7 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EMC93159.1 - 0.68 9.5 2.9 1.5 8.4 2.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1860 PF08949.5 EMC93161.1 - 0.037 13.6 0.2 0.044 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) MFS_1 PF07690.11 EMC93163.1 - 2.9e-42 144.6 43.9 2.9e-42 144.6 30.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC93163.1 - 1.7e-11 43.3 10.4 1.7e-11 43.3 7.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EMC93163.1 - 0.0042 15.2 2.3 0.0042 15.2 1.6 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.10 EMC93163.1 - 0.069 11.8 26.6 0.51 8.9 6.0 2.3 2 0 0 2 2 2 0 PUCC protein YqjK PF13997.1 EMC93163.1 - 0.4 10.8 4.7 29 4.9 0.1 4.0 4 0 0 4 4 4 0 YqjK-like protein PCI PF01399.22 EMC93164.1 - 1.6e-15 57.2 0.0 6.4e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 EMC93164.1 - 0.0057 16.9 0.0 1.2 9.5 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC93164.1 - 0.0089 15.9 0.0 0.13 12.2 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat RPN7 PF10602.4 EMC93164.1 - 0.021 14.1 0.1 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Foie-gras_1 PF11817.3 EMC93164.1 - 0.086 12.3 0.3 9 5.6 0.0 2.4 2 0 0 2 2 2 0 Foie gras liver health family 1 TFIIF_beta PF02270.10 EMC93165.1 - 7e-55 186.7 0.0 9.1e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Cys_Met_Meta_PP PF01053.15 EMC93166.1 - 3.2e-137 456.9 0.0 3.6e-137 456.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMC93166.1 - 1.4e-07 30.8 0.0 2.5e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMC93166.1 - 2.8e-05 23.3 0.1 6.2e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EMC93166.1 - 5.2e-05 22.1 0.1 9.3e-05 21.3 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMC93166.1 - 0.0023 17.1 0.0 0.005 16.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EMC93166.1 - 0.022 13.4 0.2 0.066 11.8 0.0 1.7 2 0 0 2 2 2 0 Glycine cleavage system P-protein TPP_enzyme_N PF02776.13 EMC93167.1 - 2.8e-43 147.3 0.6 1.4e-42 145.0 0.8 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMC93167.1 - 1.6e-37 128.4 1.0 8.4e-37 126.0 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMC93167.1 - 9e-20 70.8 0.0 1.8e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain UPF0029 PF01205.14 EMC93168.1 - 4.5e-16 58.4 0.2 1.3e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 VWA_2 PF13519.1 EMC93169.1 - 6e-12 46.0 0.1 7.9e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EMC93169.1 - 4.8e-08 32.8 0.0 6.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EMC93169.1 - 0.0037 16.7 0.6 0.013 15.0 0.4 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Dynein_heavy PF03028.10 EMC93169.1 - 0.042 11.8 0.0 0.058 11.4 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor Nbl1_Borealin_N PF10444.4 EMC93170.1 - 0.00083 18.6 0.2 0.0015 17.8 0.2 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal MAGUK_N_PEST PF10608.4 EMC93170.1 - 1.3 9.5 4.3 4.7 7.6 0.0 2.9 2 1 1 3 3 3 0 Polyubiquitination (PEST) N-terminal domain of MAGUK AAL_decarboxy PF03306.8 EMC93172.1 - 2e-70 236.2 0.2 2.3e-70 236.1 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase PAN_4 PF14295.1 EMC93176.1 - 0.00099 18.7 1.6 0.00099 18.7 1.1 1.5 2 0 0 2 2 2 1 PAN domain HATPase_c PF02518.21 EMC93177.1 - 3.3e-27 94.3 0.1 8.7e-27 93.0 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EMC93177.1 - 1.8e-26 92.5 0.0 3.3e-15 56.3 0.0 3.3 3 0 0 3 3 3 2 PAS domain Response_reg PF00072.19 EMC93177.1 - 4e-22 78.3 0.4 8.6e-22 77.2 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMC93177.1 - 1.3e-17 63.4 0.2 3.8e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EMC93177.1 - 2.7e-17 62.7 0.0 1.1e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EMC93177.1 - 2.5e-16 59.4 0.0 2.1e-07 30.7 0.0 3.1 2 1 2 4 4 4 2 PAS fold PAS_10 PF13596.1 EMC93177.1 - 0.00017 21.7 0.0 0.012 15.9 0.0 2.5 2 0 0 2 2 2 1 PAS domain DAO PF01266.19 EMC93179.1 - 1.1e-37 129.7 0.1 1.4e-37 129.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 EMC93179.1 - 4.8e-13 48.5 0.0 4.4e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 EMC93179.1 - 1.8e-06 27.8 0.4 4.5e-06 26.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMC93179.1 - 7.1e-05 22.0 0.2 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMC93179.1 - 9.4e-05 21.6 0.3 0.024 13.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC93179.1 - 0.00033 20.5 0.1 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC93179.1 - 0.00061 19.9 0.0 0.004 17.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC93179.1 - 0.00063 20.0 0.2 0.0015 18.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC93179.1 - 0.0012 17.9 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EMC93179.1 - 0.0013 17.6 0.1 0.002 17.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EMC93179.1 - 0.045 13.4 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMC93179.1 - 0.075 11.4 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EMC93179.1 - 0.095 12.0 0.2 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EMC93179.1 - 0.1 11.4 0.1 0.18 10.6 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A An_peroxidase PF03098.10 EMC93180.1 - 4.3e-122 408.2 0.0 5e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Peroxidase_2 PF01328.12 EMC93181.1 - 8.6e-21 73.9 0.0 1.2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 CBM_X PF06204.6 EMC93181.1 - 0.13 11.7 0.7 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative carbohydrate binding domain 3Beta_HSD PF01073.14 EMC93182.1 - 1.9e-54 184.3 0.0 2.4e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC93182.1 - 3.5e-29 101.8 0.0 6e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC93182.1 - 1.6e-14 53.4 0.1 3.2e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EMC93182.1 - 1.3e-11 43.9 0.0 3.2e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMC93182.1 - 1.4e-09 38.2 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMC93182.1 - 8.2e-09 35.5 0.1 2.1e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMC93182.1 - 5.6e-07 28.7 0.7 6.3e-06 25.3 0.5 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EMC93182.1 - 3.1e-06 26.9 0.2 2.1e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EMC93182.1 - 0.0097 15.1 0.1 0.027 13.7 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 EMC93182.1 - 0.15 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HECT_2 PF09814.4 EMC93183.1 - 4.8e-37 127.4 0.1 5.9e-37 127.1 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-C2H2 PF00096.21 EMC93185.1 - 0.00035 20.7 5.3 0.00035 20.7 3.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC93185.1 - 0.014 15.7 20.9 0.016 15.5 2.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC93185.1 - 0.069 13.4 15.3 0.12 12.7 2.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EMC93185.1 - 0.87 9.9 17.7 0.9 9.9 0.5 3.7 3 0 0 3 3 3 0 Zinc-finger double domain TGT PF01702.13 EMC93187.1 - 1.4e-88 296.1 0.0 1.9e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase YhdB PF14148.1 EMC93187.1 - 0.14 11.9 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 YhdB-like protein DUF4095 PF13338.1 EMC93188.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) PTS_EIIC_2 PF13303.1 EMC93188.1 - 0.14 10.9 1.5 0.6 8.9 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase system, EIIC UBA PF00627.26 EMC93189.1 - 8.2e-08 31.8 0.0 1.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 EMC93189.1 - 1.1e-07 31.1 0.0 1.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.1 EMC93189.1 - 0.0048 16.4 0.1 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA_3 PF09288.5 EMC93189.1 - 0.0051 16.3 0.0 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain YukD PF08817.5 EMC93189.1 - 0.0062 17.0 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PRO8NT PF08082.6 EMC93189.1 - 0.038 13.6 2.1 0.059 13.0 1.5 1.2 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Rad60-SLD PF11976.3 EMC93189.1 - 0.083 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NOG1 PF06858.9 EMC93191.1 - 1e-26 92.5 0.7 2.3e-26 91.4 0.5 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EMC93191.1 - 6.8e-26 89.7 2.4 1.6e-25 88.4 1.7 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EMC93191.1 - 4.9e-14 52.2 0.0 9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC93191.1 - 1.7e-07 30.6 0.0 3.3e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EMC93191.1 - 0.0003 20.0 0.1 0.00049 19.2 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC93191.1 - 0.00049 20.5 0.0 0.0014 19.0 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EMC93191.1 - 0.013 15.3 1.7 4.5 7.0 0.0 2.9 2 1 1 3 3 3 0 Dynamin family T3SS_LEE_assoc PF13327.1 EMC93191.1 - 0.021 14.3 0.3 0.052 13.1 0.2 1.6 1 0 0 1 1 1 0 Type III secretion system subunit AAA_17 PF13207.1 EMC93191.1 - 0.045 14.5 0.4 2.7 8.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Glyco_hydro_18 PF00704.23 EMC93193.1 - 8.4e-10 38.6 1.7 1e-09 38.3 0.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 HLH PF00010.21 EMC93194.1 - 1e-16 60.3 1.5 1.3e-16 60.0 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FlxA PF14282.1 EMC93194.1 - 4.4 7.2 7.9 0.83 9.6 0.3 2.8 2 0 0 2 2 2 0 FlxA-like protein UAA PF08449.6 EMC93195.1 - 5e-74 248.9 13.0 6.4e-74 248.5 9.0 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EMC93195.1 - 6.4e-06 25.4 0.8 6.4e-06 25.4 0.6 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EMC93195.1 - 0.033 14.2 21.8 0.03 14.3 3.4 3.2 2 1 1 3 3 3 0 EamA-like transporter family EmrE PF13536.1 EMC93195.1 - 0.25 11.5 21.2 0.19 11.9 3.5 3.2 2 1 1 3 3 3 0 Multidrug resistance efflux transporter TPT PF03151.11 EMC93195.1 - 1.3 8.6 19.0 0.083 12.5 7.0 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family MS_channel PF00924.13 EMC93196.1 - 3.3e-22 78.8 1.1 5.2e-22 78.1 0.8 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EMC93196.1 - 0.00016 20.6 0.3 0.00039 19.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EMC93196.1 - 0.00027 20.1 0.0 0.00068 18.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EMC93196.1 - 0.00056 19.9 0.2 0.0013 18.7 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC93196.1 - 0.0012 18.5 0.1 0.0038 16.9 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain DUF2945 PF11160.3 EMC93198.1 - 1.6e-14 53.4 0.1 6e-14 51.6 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Cyclin PF08613.6 EMC93199.1 - 5.8e-28 98.1 0.0 6.8e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMC93199.1 - 4.3e-06 26.2 0.0 5.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain HTH_3 PF01381.17 EMC93199.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix DUF4604 PF15377.1 EMC93201.1 - 0.039 14.1 0.3 0.086 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PWI PF01480.12 EMC93203.1 - 4.3e-05 23.5 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EMC93203.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aromatic_hydrox PF11723.3 EMC93203.1 - 0.95 8.7 4.7 5.1 6.3 3.1 2.0 2 0 0 2 2 2 0 Homotrimeric ring hydroxylase Ribosomal_S21 PF01165.15 EMC93204.1 - 1.6e-12 46.6 5.7 3.1e-12 45.7 4.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 TENA_THI-4 PF03070.11 EMC93205.1 - 5.8e-11 42.5 0.0 1.2e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Amidoligase_2 PF12224.3 EMC93206.1 - 4.2e-18 65.8 0.2 2.2e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme Fungal_trans PF04082.13 EMC93207.1 - 3.4e-29 101.4 0.0 2.4e-28 98.7 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93207.1 - 1.3e-07 31.3 8.2 2.1e-07 30.7 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2781 PF10914.3 EMC93208.1 - 4.8e-37 127.0 11.9 5.5e-37 126.8 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DC_STAMP PF07782.8 EMC93208.1 - 0.062 12.9 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 DC-STAMP-like protein zf-C2H2 PF00096.21 EMC93209.1 - 2.2e-06 27.6 28.4 0.00014 21.9 2.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC93209.1 - 0.053 13.8 23.8 0.33 11.3 3.4 4.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC93209.1 - 0.097 13.0 25.4 0.92 9.9 1.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Lipase_GDSL PF00657.17 EMC93212.1 - 7.5e-15 55.3 0.4 9.9e-15 54.9 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMC93212.1 - 3.6e-05 23.9 2.5 6.8e-05 23.0 1.7 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pro_isomerase PF00160.16 EMC93213.1 - 5.9e-44 150.0 0.0 6.6e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPT2 PF08243.6 EMC93214.1 - 2.6e-06 27.7 17.6 2.6e-06 27.7 12.2 2.1 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 EMC93215.1 - 1.2e-25 89.7 21.2 2.6e-24 85.4 14.7 2.0 1 1 0 1 1 1 1 60s Acidic ribosomal protein Bindin PF02084.10 EMC93215.1 - 9.5 6.1 9.7 8.3 6.3 4.5 1.9 1 1 1 2 2 2 0 Bindin Ribosomal_S19 PF00203.16 EMC93216.1 - 4.1e-30 103.2 0.3 4.7e-30 103.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DPPIV_N PF00930.16 EMC93217.1 - 3.6e-103 344.8 0.5 4.8e-103 344.4 0.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMC93217.1 - 2.9e-51 173.7 3.5 5.3e-51 172.8 2.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC93217.1 - 2e-11 43.8 0.1 4e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC93217.1 - 3.3e-09 36.9 0.1 2.6e-08 34.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMC93217.1 - 0.00011 21.7 2.3 0.00025 20.5 1.0 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 EMC93217.1 - 0.04 13.3 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EMC93217.1 - 0.051 13.1 0.1 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PD40 PF07676.7 EMC93217.1 - 1.3 8.7 5.8 12 5.6 0.1 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat p450 PF00067.17 EMC93219.1 - 5.3e-10 38.4 0.0 5.7e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Isochorismatase PF00857.15 EMC93220.1 - 5.7e-27 94.7 0.0 2.3e-26 92.8 0.0 2.0 2 1 0 2 2 2 1 Isochorismatase family CTDII PF01556.13 EMC93221.1 - 1.7e-26 91.9 2.7 4e-21 74.7 0.2 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EMC93221.1 - 2.4e-22 78.3 1.2 3.8e-22 77.7 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMC93221.1 - 2.1e-10 40.4 21.3 4e-10 39.6 14.7 1.5 1 0 0 1 1 1 1 DnaJ central domain BRO1 PF03097.13 EMC93222.1 - 8.6e-135 449.2 4.6 8.6e-135 449.2 3.2 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMC93222.1 - 1.9e-94 315.9 17.9 1.9e-94 315.9 12.4 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV ADK PF00406.17 EMC93222.1 - 0.25 11.2 3.9 0.57 10.0 2.7 1.6 1 0 0 1 1 1 0 Adenylate kinase DUF3012 PF11216.3 EMC93222.1 - 0.4 10.4 1.2 0.66 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) TACC PF05010.9 EMC93222.1 - 0.91 9.2 18.3 0.018 14.7 5.0 2.6 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) LysM PF01476.15 EMC93223.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain FAD_binding_2 PF00890.19 EMC93224.1 - 3.4e-115 385.2 3.2 4.7e-115 384.7 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMC93224.1 - 4.2e-41 139.8 0.3 6.2e-41 139.2 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EMC93224.1 - 9.1e-07 28.9 0.1 0.00095 19.0 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC93224.1 - 9.1e-05 21.6 0.6 0.021 13.9 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EMC93224.1 - 0.00013 21.0 1.6 0.0098 14.7 1.5 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 EMC93224.1 - 0.00083 18.3 0.2 0.0028 16.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMC93224.1 - 0.0056 15.7 0.5 0.0087 15.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMC93224.1 - 0.018 13.4 4.3 0.13 10.6 0.3 2.7 3 0 0 3 3 3 0 HI0933-like protein PAT1 PF09770.4 EMC93225.1 - 5.7 5.0 8.2 6.2 4.9 5.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp_Glu_race PF01177.17 EMC93226.1 - 5.5e-20 72.2 0.3 6.4e-20 71.9 0.2 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Nup35_RRM_2 PF14605.1 EMC93226.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sds3 PF08598.6 EMC93227.1 - 2.9e-23 82.4 1.1 2.9e-23 82.4 0.8 2.9 2 2 0 2 2 2 1 Sds3-like RRM_1 PF00076.17 EMC93228.1 - 8.7e-12 44.5 0.5 3.4e-10 39.4 0.0 3.4 5 0 0 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC93228.1 - 7.5e-09 35.3 0.0 4.3e-06 26.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC93228.1 - 9.4e-08 31.9 0.2 9.3e-07 28.7 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PMT PF02366.13 EMC93229.1 - 1.6e-80 270.0 18.6 2.8e-80 269.2 12.9 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMC93229.1 - 9.6e-18 64.3 0.3 6.8e-17 61.6 0.1 2.1 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EMC93229.1 - 1.2e-06 28.4 10.2 1.2e-06 28.4 7.1 3.6 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase 3Beta_HSD PF01073.14 EMC93230.1 - 1.6e-14 53.3 0.0 3.5e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC93230.1 - 1.5e-12 47.5 0.0 4.4e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC93230.1 - 1.3e-09 38.3 0.2 3.6e-09 36.8 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMC93230.1 - 7.2e-09 34.9 0.1 3.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EMC93230.1 - 5.6e-07 29.0 0.1 1.3e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EMC93230.1 - 1.5e-05 24.9 1.7 0.00016 21.6 1.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMC93230.1 - 8.6e-05 21.5 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EMC93230.1 - 0.00012 21.7 2.1 0.0031 17.1 1.5 2.3 1 1 0 1 1 1 1 KR domain ATP-synt_ab PF00006.20 EMC93231.1 - 1.7e-71 240.1 0.0 2.6e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMC93231.1 - 2.5e-25 89.1 1.6 6.2e-25 87.8 0.4 2.3 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMC93231.1 - 2.8e-16 59.4 3.0 1.1e-15 57.6 2.1 2.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMC93231.1 - 0.02 14.8 3.3 0.052 13.4 1.0 2.5 2 1 0 2 2 2 0 HAS barrel domain DUF962 PF06127.6 EMC93232.1 - 2e-25 88.5 1.7 3.1e-25 87.8 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF4243 PF14027.1 EMC93233.1 - 1.9e-79 267.4 4.6 2.4e-79 267.2 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Imm31 PF15595.1 EMC93233.1 - 0.037 13.7 0.5 0.14 11.9 0.0 2.1 3 0 0 3 3 3 0 Immunity protein 31 SlyX PF04102.7 EMC93234.1 - 0.0035 17.6 0.1 1.2 9.5 0.0 2.1 2 0 0 2 2 2 2 SlyX Med8 PF10232.4 EMC93234.1 - 0.013 15.0 0.1 0.021 14.3 0.1 1.5 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Baculo_PEP_C PF04513.7 EMC93234.1 - 0.08 12.7 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EMC93234.1 - 0.14 12.0 0.2 22 5.0 0.0 2.5 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) RNase_T PF00929.19 EMC93235.1 - 1.3e-22 80.8 0.0 2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease YqeY PF09424.5 EMC93236.1 - 8.3e-22 77.5 9.0 9.9e-22 77.3 6.3 1.1 1 0 0 1 1 1 1 Yqey-like protein CM_2 PF01817.16 EMC93236.1 - 0.0069 16.4 0.4 0.016 15.2 0.3 1.6 1 0 0 1 1 1 1 Chorismate mutase type II CBP4 PF07960.6 EMC93236.1 - 0.057 13.0 0.4 0.086 12.4 0.3 1.3 1 0 0 1 1 1 0 CBP4 Nucleoporin_C PF03177.9 EMC93237.1 - 6.1e-119 398.1 0.2 7.6e-119 397.8 0.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EMC93237.1 - 4.3e-63 213.5 0.0 5.6e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like NUMOD1 PF07453.8 EMC93237.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain WD40 PF00400.27 EMC93238.1 - 7.9e-20 69.9 10.4 0.00034 20.3 0.3 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 EMC93239.1 - 1.2e-31 109.6 10.7 1.2e-31 109.6 7.4 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 4 Glyco_hydro_71 PF03659.9 EMC93240.1 - 4.7e-74 249.1 12.6 6.2e-74 248.7 8.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Amidase PF01425.16 EMC93241.1 - 2.7e-52 178.0 0.3 2e-51 175.2 0.2 2.1 1 1 0 1 1 1 1 Amidase Aldolase_II PF00596.16 EMC93242.1 - 4.2e-46 156.8 0.0 5.3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain R3H-assoc PF13902.1 EMC93243.1 - 7.7e-22 77.6 9.1 9.2e-22 77.4 5.2 2.0 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 EMC93243.1 - 0.00097 18.7 0.3 0.0039 16.8 0.0 2.2 2 0 0 2 2 2 1 R3H domain IncA PF04156.9 EMC93243.1 - 0.83 9.2 4.1 1.2 8.6 2.8 1.4 1 0 0 1 1 1 0 IncA protein Rick_17kDa_Anti PF05433.10 EMC93244.1 - 0.024 14.2 9.3 0.075 12.7 6.4 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EMC93244.1 - 2.2 8.0 11.5 6 6.5 8.0 1.7 1 0 0 1 1 1 0 Glycine zipper Leukocidin PF07968.7 EMC93245.1 - 0.11 12.1 0.3 3.8 7.0 0.0 2.0 1 1 1 2 2 2 0 Leukocidin/Hemolysin toxin family NUFIP1 PF10453.4 EMC93247.1 - 8.5e-12 44.4 0.7 2.3e-11 43.0 0.5 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EMC93247.1 - 2.2e-05 23.9 4.9 3.4e-05 23.4 3.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HlyD PF00529.15 EMC93247.1 - 0.0044 16.3 0.1 0.0093 15.3 0.1 1.5 1 0 0 1 1 1 1 HlyD family secretion protein zf-CCCH_2 PF14608.1 EMC93247.1 - 0.02 14.8 1.7 0.054 13.5 1.1 1.8 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type RNA_pol_Rbc25 PF08292.7 EMC93248.1 - 8.5e-26 90.5 0.1 1.2e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EMC93248.1 - 1.7e-14 53.6 0.1 2.6e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 zf-GRF PF06839.7 EMC93250.1 - 1.1e-09 38.0 6.2 3.7e-09 36.3 4.2 1.9 2 0 0 2 2 2 1 GRF zinc finger Fungal_trans PF04082.13 EMC93251.1 - 1.5e-25 89.6 0.0 2.2e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93251.1 - 7.3e-05 22.5 18.1 0.00013 21.7 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTPase_Cys_C PF12631.2 EMC93251.1 - 1.7 9.0 3.8 0.88 10.0 0.2 2.4 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE MFS_1 PF07690.11 EMC93252.1 - 1.4e-31 109.5 29.3 1.4e-31 109.5 20.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 EMC93252.1 - 0.63 10.1 0.0 0.63 10.1 0.0 3.0 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DHDPS PF00701.17 EMC93253.1 - 3.8e-39 134.0 0.0 4.5e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.17 EMC93253.1 - 0.098 12.3 0.0 0.41 10.3 0.0 2.1 2 1 0 2 2 2 0 PA domain MFS_1 PF07690.11 EMC93255.1 - 7e-45 153.2 39.5 7e-45 153.2 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC93255.1 - 9.5e-13 47.5 38.3 2.7e-12 46.0 26.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.1 EMC93255.1 - 2.2 7.6 11.6 0.63 9.4 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) MTP18 PF10558.4 EMC93256.1 - 5.1e-64 214.6 0.1 6.3e-64 214.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) RecA PF00154.16 EMC93257.1 - 8.7e-07 28.3 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EMC93257.1 - 2.4e-06 27.0 1.3 1.2e-05 24.8 0.9 2.0 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 EMC93257.1 - 0.0012 17.7 0.0 0.0054 15.6 0.0 1.9 1 1 0 1 1 1 1 Rad51 KaiC PF06745.8 EMC93257.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 KaiC MOSC PF03473.12 EMC93258.1 - 7.9e-14 51.2 0.0 2e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EMC93258.1 - 1.2e-12 47.5 0.0 2.3e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2526 PF10735.4 EMC93260.1 - 0.022 14.7 0.5 0.042 13.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) PALP PF00291.20 EMC93261.1 - 6.2e-60 203.0 0.0 1.1e-59 202.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EMC93261.1 - 7e-10 38.5 0.1 6.3e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 CBS domain NAD_binding_2 PF03446.10 EMC93262.1 - 3e-26 92.2 0.1 4.5e-26 91.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMC93262.1 - 9.6e-09 35.3 0.0 1.7e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMC93262.1 - 4.2e-05 23.8 0.2 0.00016 22.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EMC93262.1 - 6e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMC93262.1 - 0.0035 16.7 0.1 0.0088 15.4 0.1 1.5 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ETF PF01012.16 EMC93262.1 - 0.0069 16.1 0.3 1.2 8.8 0.0 2.4 1 1 1 2 2 2 2 Electron transfer flavoprotein domain OCD_Mu_crystall PF02423.10 EMC93262.1 - 0.021 13.5 0.3 0.067 11.9 0.1 1.7 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family ETC_C1_NDUFA5 PF04716.9 EMC93265.1 - 2.2e-19 68.7 0.2 2.7e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Thioredoxin PF00085.15 EMC93266.1 - 2.2e-44 149.3 0.0 2.7e-25 88.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EMC93266.1 - 2.2e-12 47.1 0.0 2.9e-05 23.9 0.0 3.8 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC93266.1 - 2.3e-08 34.0 0.0 0.003 17.6 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EMC93266.1 - 9e-05 22.4 0.3 0.0038 17.2 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC93266.1 - 0.0005 20.2 6.3 0.083 13.0 0.1 4.2 4 2 0 4 4 4 2 Thioredoxin-like domain HyaE PF07449.6 EMC93266.1 - 0.0019 18.0 0.0 2.3 8.1 0.0 3.1 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE DUF4399 PF14347.1 EMC93267.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Rot1 PF10681.4 EMC93268.1 - 7.9e-90 299.8 0.1 9.2e-90 299.6 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.1 EMC93268.1 - 0.035 14.7 0.3 0.086 13.4 0.2 1.6 1 1 0 1 1 1 0 Lipocalin-like domain 5-FTHF_cyc-lig PF01812.15 EMC93269.1 - 5.4e-38 130.6 0.0 6.4e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 EMC93270.1 - 2.1e-16 59.1 0.0 2.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain Xpo1 PF08389.7 EMC93271.1 - 5e-30 104.3 7.8 1.8e-29 102.5 1.6 3.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EMC93271.1 - 3.1e-06 27.0 0.0 1.3e-05 24.9 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EMC93271.1 - 4.8e-05 23.5 0.6 0.0025 18.0 0.0 3.9 4 1 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.15 EMC93271.1 - 0.0034 15.7 0.4 0.064 11.5 0.1 2.3 2 0 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.17 EMC93271.1 - 0.005 16.8 0.7 29 5.0 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 EMC93271.1 - 0.0051 17.2 0.3 0.18 12.3 0.0 3.8 3 0 0 3 3 3 1 HEAT-like repeat DUF2937 PF11157.3 EMC93271.1 - 1.5 8.1 6.1 14 4.9 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2937) Sugar_tr PF00083.19 EMC93272.1 - 1.4e-84 284.2 28.8 1.7e-84 284.0 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC93272.1 - 1.3e-16 60.3 42.9 6.1e-12 44.9 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC93272.1 - 0.00069 18.1 30.0 0.0028 16.1 3.4 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein SdpI PF13630.1 EMC93272.1 - 3.9 7.2 14.5 0.48 10.1 1.2 3.7 2 1 1 3 3 3 0 SdpI/YhfL protein family ZZ PF00569.12 EMC93273.1 - 0.00011 21.6 2.4 0.00027 20.4 1.6 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.15 EMC93273.1 - 0.004 16.8 1.0 0.0097 15.6 0.7 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) SAP30_Sin3_bdg PF13867.1 EMC93275.1 - 9.9e-10 38.1 0.1 1.8e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2888 PF11135.3 EMC93275.1 - 0.062 13.0 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) Ground-like PF04155.13 EMC93275.1 - 0.083 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Ground-like domain Dynamin_M PF01031.15 EMC93276.1 - 3.7e-111 370.6 0.0 6.7e-111 369.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EMC93276.1 - 1.6e-55 187.4 0.0 1.6e-55 187.4 0.0 2.2 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EMC93276.1 - 2.4e-32 110.6 2.7 6.1e-32 109.3 1.9 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMC93276.1 - 0.00037 20.4 0.1 0.0019 18.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC93276.1 - 0.017 15.6 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein PBP PF01161.15 EMC93277.1 - 2.1e-23 82.7 0.1 3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LSM PF01423.17 EMC93280.1 - 4.7e-14 51.6 1.8 7.7e-14 51.0 0.6 1.8 2 0 0 2 2 2 1 LSM domain Methyltransf_11 PF08241.7 EMC93280.1 - 1e-07 32.3 0.0 2.5e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC93280.1 - 0.039 13.6 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribul_P_3_epim PF00834.14 EMC93281.1 - 4.6e-50 169.5 0.0 1.2e-48 164.8 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EMC93281.1 - 0.0031 17.0 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 EMC93281.1 - 0.0063 15.9 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Glyco_hydro_31 PF01055.21 EMC93281.1 - 0.013 14.3 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 PcrB PF01884.12 EMC93281.1 - 0.013 14.7 0.3 0.026 13.7 0.2 1.5 1 1 0 1 1 1 0 PcrB family TAFII55_N PF04658.8 EMC93282.1 - 4.4e-50 169.3 0.2 9.1e-50 168.3 0.1 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Bromo_TP PF07524.8 EMC93283.1 - 2.3e-09 36.8 0.0 3.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AA_permease_2 PF13520.1 EMC93285.1 - 7.5e-46 156.5 39.9 9.9e-46 156.1 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC93285.1 - 2.8e-24 85.2 35.6 4.9e-24 84.5 24.7 1.4 1 1 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EMC93287.1 - 1.5e-16 60.7 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93287.1 - 2.5e-05 24.0 0.1 6.6e-05 22.6 0.0 1.6 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMC93287.1 - 2.6e-05 24.0 0.1 6.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.14 EMC93288.1 - 1.3e-84 284.2 0.0 1.6e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC93288.1 - 0.0059 16.5 0.1 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC93288.1 - 0.79 9.7 2.7 2.1 8.4 1.9 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain cobW PF02492.14 EMC93289.1 - 2.5e-44 150.8 0.1 3.6e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EMC93289.1 - 0.00029 20.4 0.0 0.0006 19.4 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_23 PF13476.1 EMC93289.1 - 0.00095 19.5 0.1 0.0029 17.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EMC93289.1 - 0.0053 15.5 1.0 1 8.0 0.0 2.9 3 0 0 3 3 3 1 ArgK protein AAA_16 PF13191.1 EMC93289.1 - 0.0055 16.7 0.3 0.2 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 EMC93289.1 - 0.0063 15.9 0.8 0.59 9.5 0.6 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 EMC93289.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 EMC93289.1 - 0.012 15.9 0.0 0.048 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMC93289.1 - 0.015 15.0 0.1 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 EMC93289.1 - 0.02 14.8 0.2 0.051 13.5 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC93289.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMC93289.1 - 0.05 13.3 0.0 0.19 11.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EMC93289.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMC93289.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EMC93289.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EMC93289.1 - 0.095 11.7 0.3 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 EMC93289.1 - 0.1 12.9 2.5 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 EMC93289.1 - 0.1 12.1 2.3 0.12 11.9 0.0 2.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain NapB PF03892.9 EMC93290.1 - 0.071 12.7 0.6 0.098 12.3 0.4 1.2 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) PAS_9 PF13426.1 EMC93291.1 - 1e-08 35.4 0.0 4.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EMC93291.1 - 1.7e-07 31.2 0.0 1.5e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EMC93291.1 - 0.0002 21.3 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 EMC93291.1 - 0.00022 21.1 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EMC93291.1 - 0.00038 20.2 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 PAS fold DUF448 PF04296.8 EMC93291.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF448) DUF605 PF04652.11 EMC93291.1 - 0.12 11.7 10.5 0.18 11.1 7.3 1.2 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 EMC93292.1 - 5.2e-19 67.3 5.3 3.9e-10 39.2 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PD40 PF07676.7 EMC93292.1 - 0.025 14.2 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Mob1_phocein PF03637.12 EMC93293.1 - 5.8e-23 81.4 0.8 2.7e-22 79.2 0.6 1.9 1 1 0 1 1 1 1 Mob1/phocein family HET PF06985.6 EMC93295.1 - 9e-12 45.3 0.0 1e-11 45.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2530 PF10745.4 EMC93298.1 - 0.087 12.8 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DEAD PF00270.24 EMC93299.1 - 2.1e-24 85.9 0.0 3.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC93299.1 - 1.9e-09 37.2 0.1 6.2e-09 35.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EMC93299.1 - 0.00039 20.3 0.0 0.00097 19.1 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like DUF1998 PF09369.5 EMC93299.1 - 0.004 17.6 0.0 0.02 15.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Mannosyl_trans3 PF11051.3 EMC93301.1 - 6.8e-70 235.4 0.0 2.6e-69 233.5 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EMC93301.1 - 0.093 12.0 0.2 0.25 10.6 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 8 Aa_trans PF01490.13 EMC93302.1 - 4.3e-27 94.6 25.0 6.6e-27 94.0 17.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_47 PF01532.15 EMC93303.1 - 2e-115 386.0 0.0 2.2e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PepX_N PF09168.5 EMC93303.1 - 0.093 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal DUF4372 PF14294.1 EMC93303.1 - 0.11 12.3 0.1 7.1 6.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4372) HAUS6_N PF14661.1 EMC93304.1 - 3.5e-40 137.9 2.0 3.7e-40 137.8 0.3 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus REV PF00424.13 EMC93304.1 - 0.0099 15.7 0.7 0.0099 15.7 0.5 2.1 2 0 0 2 2 2 1 REV protein (anti-repression trans-activator protein) RIP PF00161.14 EMC93304.1 - 0.067 12.3 0.4 0.96 8.5 0.0 2.2 2 0 0 2 2 2 0 Ribosome inactivating protein Methyltransf_8 PF05148.10 EMC93305.1 - 8.4e-57 192.3 0.0 2.5e-55 187.4 0.0 2.8 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EMC93305.1 - 1.2e-05 25.6 0.0 5.2e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMC93305.1 - 0.066 12.9 0.0 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMC93305.1 - 0.13 11.8 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain BH4 PF02180.12 EMC93306.1 - 0.018 14.5 0.0 0.053 13.0 0.0 1.8 1 0 0 1 1 1 0 Bcl-2 homology region 4 AAA PF00004.24 EMC93308.1 - 5.5e-37 126.9 0.0 8.4e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMC93308.1 - 5.1e-06 25.7 0.0 9.1e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMC93308.1 - 6.6e-06 26.9 0.0 1.5e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC93308.1 - 9.5e-06 25.5 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC93308.1 - 1.2e-05 24.7 0.5 0.023 14.0 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EMC93308.1 - 1.3e-05 25.3 0.1 0.00034 20.7 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMC93308.1 - 2.1e-05 24.5 0.3 0.00047 20.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EMC93308.1 - 4.8e-05 23.3 0.0 8.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EMC93308.1 - 6.5e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC93308.1 - 7e-05 22.5 0.2 0.00062 19.5 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EMC93308.1 - 0.00047 19.6 0.0 0.0009 18.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMC93308.1 - 0.00064 18.9 0.1 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMC93308.1 - 0.00083 19.4 0.0 0.0021 18.2 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EMC93308.1 - 0.0016 18.3 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC93308.1 - 0.0022 18.3 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EMC93308.1 - 0.0024 17.9 0.0 0.0066 16.5 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 EMC93308.1 - 0.0026 16.9 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EMC93308.1 - 0.0026 17.4 0.0 0.008 15.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 EMC93308.1 - 0.0041 16.7 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMC93308.1 - 0.008 16.4 0.0 0.016 15.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EMC93308.1 - 0.0094 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EMC93308.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 EMC93308.1 - 0.043 13.4 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.10 EMC93308.1 - 0.046 12.4 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EMC93308.1 - 0.053 12.2 0.0 0.094 11.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Parvo_NS1 PF01057.12 EMC93308.1 - 0.059 12.2 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EMC93308.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase SKI PF01202.17 EMC93308.1 - 0.06 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Viral_helicase1 PF01443.13 EMC93308.1 - 0.061 12.8 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 EMC93308.1 - 0.064 12.3 0.0 0.53 9.3 0.0 2.0 1 1 1 2 2 2 0 KaiC AAA_21 PF13304.1 EMC93308.1 - 0.072 13.0 0.1 16 5.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EMC93308.1 - 0.075 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EMC93308.1 - 0.093 12.1 0.1 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EMC93308.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EMC93308.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 EMC93308.1 - 0.11 11.4 0.1 0.43 9.5 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain Thymidylat_synt PF00303.14 EMC93309.1 - 2.3e-78 262.9 0.0 2.8e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Aldedh PF00171.17 EMC93310.1 - 4e-156 519.9 0.0 4.6e-156 519.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC93310.1 - 0.2 10.3 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Abhydrolase_6 PF12697.2 EMC93311.1 - 4.8e-22 78.9 0.0 1.1e-21 77.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93311.1 - 8.5e-12 45.1 0.0 7.4e-10 38.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93311.1 - 2.3e-09 37.1 0.0 1e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FMN_dh PF01070.13 EMC93312.1 - 1.9e-115 385.5 0.0 2.3e-115 385.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EMC93312.1 - 5.1e-05 22.5 0.2 8.9e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EMC93312.1 - 0.00023 20.3 0.8 0.075 12.0 0.1 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EMC93312.1 - 0.00077 18.4 1.3 0.0013 17.6 0.6 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMC93312.1 - 0.0036 16.2 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IGPS PF00218.16 EMC93312.1 - 0.12 11.3 0.2 1.1 8.3 0.1 2.0 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase MRP-L47 PF06984.8 EMC93313.1 - 1.6e-18 66.3 0.1 2.4e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.13 EMC93315.1 - 1.8e-168 560.4 0.0 2.2e-168 560.1 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor G2F PF07474.7 EMC93315.1 - 0.033 13.5 0.0 0.084 12.2 0.0 1.6 2 0 0 2 2 2 0 G2F domain Cellulase PF00150.13 EMC93316.1 - 3.4e-16 59.2 0.0 4.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Adeno_E3_CR2 PF02439.10 EMC93318.1 - 0.084 12.4 0.3 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ABC_membrane PF00664.18 EMC93318.1 - 0.097 12.0 0.0 0.8 9.0 0.0 2.0 1 1 1 2 2 2 0 ABC transporter transmembrane region Fungal_trans PF04082.13 EMC93320.1 - 4.6e-59 199.4 0.7 7.3e-59 198.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EMC93320.1 - 0.0018 18.4 15.2 0.003 17.7 3.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC93320.1 - 0.0034 17.5 10.4 0.11 12.8 2.3 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC93320.1 - 0.0046 17.2 3.8 0.0046 17.2 2.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type SUFU_C PF12470.3 EMC93321.1 - 0.045 13.3 0.1 0.059 12.9 0.1 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain HD_3 PF13023.1 EMC93322.1 - 1.1e-47 161.8 0.1 1.6e-47 161.3 0.1 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 EMC93322.1 - 0.0036 17.3 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 HD domain U-box PF04564.10 EMC93323.1 - 4.4e-20 71.4 0.1 1e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EMC93323.1 - 1.2e-16 60.1 5.3 1.4e-15 56.6 0.4 2.6 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMC93323.1 - 1e-08 34.4 5.7 0.0002 20.8 0.2 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC93323.1 - 2.3e-07 30.1 5.3 0.00026 20.6 0.2 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC93323.1 - 9.2e-05 23.0 6.6 0.0018 18.8 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC93323.1 - 0.00013 22.2 1.0 0.0083 16.4 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat zf-Nse PF11789.3 EMC93323.1 - 0.00015 21.2 0.1 0.00051 19.5 0.1 1.8 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_14 PF13428.1 EMC93323.1 - 0.00022 21.5 3.8 0.053 14.1 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC93323.1 - 0.00029 20.4 0.3 0.018 14.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC93323.1 - 0.0027 17.7 5.6 0.14 12.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC93323.1 - 0.006 16.6 4.0 0.034 14.2 0.5 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 A2M_comp PF07678.9 EMC93323.1 - 0.051 12.8 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 A-macroglobulin complement component RD3 PF14473.1 EMC93323.1 - 0.082 12.3 0.2 0.18 11.2 0.1 1.5 1 1 0 1 1 1 0 RD3 protein TPR_12 PF13424.1 EMC93323.1 - 0.13 12.1 0.2 0.13 12.1 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat BBP1_C PF15272.1 EMC93323.1 - 0.14 11.6 2.7 0.054 13.0 0.2 1.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal TPR_10 PF13374.1 EMC93323.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PTS_IIA PF02255.11 EMC93323.1 - 0.78 9.6 6.7 0.6 10.0 0.4 2.8 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit SRPRB PF09439.5 EMC93324.1 - 2.7e-34 117.9 0.0 1.4e-33 115.5 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EMC93324.1 - 3.1e-07 29.7 0.0 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC93324.1 - 5.7e-05 23.0 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC93324.1 - 7.3e-05 22.0 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC93324.1 - 0.00027 20.4 0.0 0.00078 18.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EMC93324.1 - 0.00031 21.2 0.0 0.0025 18.3 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EMC93324.1 - 0.00034 20.7 0.0 0.00066 19.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC93324.1 - 0.00063 19.7 0.2 0.0011 18.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EMC93324.1 - 0.0017 17.8 0.0 0.0049 16.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EMC93324.1 - 0.0024 18.1 0.2 0.005 17.1 0.1 1.6 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EMC93324.1 - 0.003 16.7 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EMC93324.1 - 0.0052 16.2 0.1 0.28 10.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EMC93324.1 - 0.0066 16.0 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.17 EMC93324.1 - 0.0066 15.8 0.0 0.038 13.3 0.0 2.0 1 1 0 1 1 1 1 Ras family Septin PF00735.13 EMC93324.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_23 PF13476.1 EMC93324.1 - 0.026 14.8 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMC93324.1 - 0.028 13.9 0.0 0.67 9.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EMC93324.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC93324.1 - 0.03 13.9 0.0 0.071 12.7 0.0 1.7 1 1 1 2 2 2 0 NACHT domain AAA_19 PF13245.1 EMC93324.1 - 0.036 13.8 0.0 0.097 12.4 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_21 PF13304.1 EMC93324.1 - 0.042 13.7 0.0 0.088 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMC93324.1 - 0.044 14.6 0.2 0.097 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EMC93324.1 - 0.044 13.9 0.3 0.14 12.4 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EMC93324.1 - 0.054 13.4 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMC93324.1 - 0.056 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.6 EMC93324.1 - 0.071 11.8 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein adh_short PF00106.20 EMC93325.1 - 3.8e-16 59.4 0.1 7.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC93325.1 - 1.8e-07 31.1 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC93325.1 - 3.3e-05 23.6 0.1 4.9e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC93325.1 - 4.9e-05 22.8 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EMC93325.1 - 0.034 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.10 EMC93325.1 - 0.037 12.9 0.1 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMC93325.1 - 0.037 14.0 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding ATP-synt_DE_N PF02823.11 EMC93325.1 - 0.043 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain NDT80_PhoG PF05224.7 EMC93326.1 - 7.1e-37 127.2 0.0 1.4e-36 126.2 0.0 1.5 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family SH3_1 PF00018.23 EMC93327.1 - 7.7e-10 38.0 1.7 1.1e-09 37.4 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC93327.1 - 9.2e-10 37.9 0.2 4e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMC93327.1 - 2.1e-06 27.1 1.7 4.2e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 EMC93328.1 - 1.7e-14 53.6 0.4 2.3e-13 49.9 0.4 2.6 2 1 0 2 2 2 1 Rtr1/RPAP2 family Pterin_bind PF00809.17 EMC93329.1 - 8.4e-65 218.0 0.0 6.1e-64 215.2 0.0 2.2 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EMC93329.1 - 1.9e-41 140.7 0.0 3.9e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 EMC93330.1 - 5.7e-71 239.3 1.3 6.9e-71 239.0 0.9 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMC93330.1 - 8.5e-09 34.7 1.7 1.5e-08 33.9 1.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EMC93330.1 - 3.7e-06 26.0 1.6 3.7e-06 26.0 1.1 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EMC93330.1 - 0.0056 15.6 2.1 0.0083 15.0 1.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EMC93330.1 - 0.022 13.7 0.3 0.038 12.9 0.2 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Syntaxin-18_N PF10496.4 EMC93331.1 - 1.9e-10 40.4 0.9 3.2e-09 36.4 0.1 3.3 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EMC93331.1 - 0.0026 17.4 1.8 0.0026 17.4 1.3 2.6 2 0 0 2 2 2 1 SNARE domain Rad50_zn_hook PF04423.9 EMC93331.1 - 0.18 11.3 1.1 2.5 7.6 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Aminotran_1_2 PF00155.16 EMC93332.1 - 1.4e-80 270.9 0.0 1.7e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Tropomyosin_1 PF12718.2 EMC93333.1 - 0.021 14.6 0.0 6.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF4254 PF14063.1 EMC93333.1 - 0.041 13.4 1.5 0.074 12.6 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) Filament PF00038.16 EMC93333.1 - 0.058 12.8 0.5 0.1 12.0 0.2 1.4 1 1 0 1 1 1 0 Intermediate filament protein bZIP_1 PF00170.16 EMC93333.1 - 0.14 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor TIM PF00121.13 EMC93334.1 - 1.6e-54 184.5 0.0 1.8e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MTHFR PF02219.12 EMC93335.1 - 9.9e-111 369.4 0.0 1.3e-110 369.0 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Tetraspannin PF00335.15 EMC93336.1 - 0.012 14.8 0.8 0.014 14.7 0.6 1.1 1 0 0 1 1 1 0 Tetraspanin family PigN PF04987.9 EMC93337.1 - 8.2e-159 528.9 15.6 1e-158 528.6 10.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EMC93337.1 - 1.1e-11 44.6 1.0 6.9e-10 38.7 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMC93337.1 - 4.3e-07 29.4 0.2 2.1e-06 27.1 0.0 2.0 1 1 1 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EMC93337.1 - 0.0022 17.3 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily HET PF06985.6 EMC93338.1 - 4.7e-14 52.7 4.2 3.9e-10 40.0 0.1 2.6 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) ATP-synt_F PF01990.12 EMC93339.1 - 4.5e-30 103.8 0.1 5.3e-30 103.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 EMC93340.1 - 1.1e-24 87.1 0.3 1.2e-24 87.0 0.2 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EMC93340.1 - 0.00054 20.0 0.2 0.0019 18.2 0.1 1.8 1 1 0 1 1 1 1 ML-like domain NPCBM_assoc PF10633.4 EMC93340.1 - 0.058 13.4 0.1 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Coatomer_WDAD PF04053.9 EMC93341.1 - 1.2e-166 554.9 0.0 4.1e-166 553.1 0.0 1.8 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 EMC93341.1 - 2.8e-45 150.6 9.3 4.4e-10 39.0 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMC93341.1 - 0.00015 20.0 2.7 0.036 12.2 0.0 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EMC93341.1 - 0.00097 18.8 0.0 1.7 8.4 0.0 3.4 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Methyltransf_2 PF00891.13 EMC93342.1 - 2.4e-35 121.9 0.0 3.2e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase adh_short PF00106.20 EMC93344.1 - 7e-32 110.6 1.2 9e-32 110.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93344.1 - 2.8e-17 62.9 0.6 4e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC93344.1 - 9.6e-13 48.4 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC93344.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC93344.1 - 0.0023 16.7 0.1 0.0031 16.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMC93344.1 - 0.0037 16.2 0.0 0.0045 15.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EMC93344.1 - 0.0058 16.3 0.4 0.013 15.2 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Chlorophyllase PF07224.6 EMC93344.1 - 0.013 14.3 0.1 0.022 13.5 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase PhyH PF05721.8 EMC93346.1 - 1.1e-28 100.6 0.1 1.4e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EMC93346.1 - 1.9e-05 24.8 0.0 3.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EMC93346.1 - 0.0064 16.9 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HD PF01966.17 EMC93347.1 - 5.2e-09 36.1 0.0 7.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_4 PF13328.1 EMC93347.1 - 0.00069 19.3 0.5 0.001 18.8 0.2 1.5 1 1 0 1 1 1 1 HD domain HDOD PF08668.7 EMC93347.1 - 0.0017 17.6 0.0 0.0047 16.2 0.0 1.7 1 1 0 1 1 1 1 HDOD domain DUF706 PF05153.10 EMC93347.1 - 0.031 13.6 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) Zn_clus PF00172.13 EMC93348.1 - 1.4e-09 37.6 8.5 2.4e-09 36.9 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC93348.1 - 4.4e-09 35.5 0.1 7.5e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NOT2_3_5 PF04153.13 EMC93349.1 - 8.2e-24 84.0 3.4 3e-23 82.2 0.0 2.6 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family CUE PF02845.11 EMC93350.1 - 7.8e-09 34.8 0.0 1.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain ATP_synt_H PF05493.8 EMC93351.1 - 1.4e-23 82.7 8.3 1.6e-23 82.5 5.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit H OppC_N PF12911.2 EMC93351.1 - 0.12 11.7 1.7 0.6 9.5 0.3 2.1 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Yip1 PF04893.12 EMC93351.1 - 0.16 11.4 7.9 0.2 11.1 5.5 1.1 1 0 0 1 1 1 0 Yip1 domain 2TM PF13239.1 EMC93351.1 - 0.84 9.7 5.0 1.2 9.2 3.4 1.2 1 0 0 1 1 1 0 2TM domain Ndc1_Nup PF09531.5 EMC93351.1 - 5.8 5.2 6.9 6.1 5.1 4.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Arv1 PF04161.8 EMC93352.1 - 9.1e-46 156.3 0.0 1.4e-45 155.7 0.0 1.3 1 1 0 1 1 1 1 Arv1-like family ACBP PF00887.14 EMC93353.1 - 4.1e-23 80.8 2.2 4.6e-23 80.6 1.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein SMC_N PF02463.14 EMC93354.1 - 8.4e-65 218.0 0.0 1.7e-64 217.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Ribosomal_S17e PF00833.13 EMC93354.1 - 1.1e-50 170.4 0.3 1.1e-50 170.4 0.2 3.1 3 0 0 3 3 3 1 Ribosomal S17 SMC_hinge PF06470.8 EMC93354.1 - 1.1e-20 73.7 1.0 3.5e-20 72.1 0.3 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EMC93354.1 - 8.7e-18 65.3 0.9 8.7e-18 65.3 0.6 6.5 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 EMC93354.1 - 7.4e-15 55.6 0.1 6.7e-07 29.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain GAS PF13851.1 EMC93354.1 - 0.00015 20.9 4.4 0.00015 20.9 3.1 7.2 3 2 4 7 7 6 2 Growth-arrest specific micro-tubule binding AAA_29 PF13555.1 EMC93354.1 - 0.00063 19.2 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 EMC93354.1 - 0.0012 18.6 10.5 0.0012 18.6 7.3 7.8 3 2 4 8 8 6 1 Tropomyosin like AAA_15 PF13175.1 EMC93354.1 - 0.0049 15.9 0.0 0.0049 15.9 0.0 3.0 2 2 0 2 2 2 1 AAA ATPase domain APG6 PF04111.7 EMC93354.1 - 0.0075 15.3 0.4 0.0075 15.3 0.3 6.8 3 2 4 7 7 6 3 Autophagy protein Apg6 ABC_tran PF00005.22 EMC93354.1 - 0.24 11.6 19.7 1.3 9.3 0.0 5.3 4 1 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EMC93354.1 - 0.34 10.0 24.7 2.2 7.4 0.7 5.7 3 2 3 6 6 6 0 Reovirus sigma C capsid protein DUF619 PF04768.8 EMC93355.1 - 3.3e-53 179.5 0.0 7.7e-53 178.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) DUF2077 PF09850.4 EMC93355.1 - 0.0057 16.0 0.1 0.65 9.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2077) LacAB_rpiB PF02502.13 EMC93356.1 - 3.7e-41 140.0 0.1 4.4e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.3 EMC93356.1 - 0.1 12.6 0.2 0.27 11.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF2620 GST_N PF02798.15 EMC93357.1 - 3.2e-07 30.4 0.0 6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMC93357.1 - 6.7e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC93357.1 - 9.5e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC93357.1 - 0.00045 20.1 0.0 0.0024 17.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC93357.1 - 0.0019 18.6 0.0 0.0038 17.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC93357.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Flavi_M PF01004.14 EMC93357.1 - 0.24 10.8 1.5 0.34 10.3 0.3 1.8 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M Fe-ADH PF00465.14 EMC93358.1 - 1.2e-52 178.8 0.0 2e-52 178.0 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMC93358.1 - 3.9e-05 23.0 0.0 0.00091 18.5 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Grp1_Fun34_YaaH PF01184.14 EMC93359.1 - 5.2e-26 91.2 20.6 7.5e-26 90.7 14.3 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Anoctamin PF04547.7 EMC93359.1 - 0.12 10.9 2.9 0.17 10.4 2.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Zn_Tnp_IS91 PF14319.1 EMC93360.1 - 0.014 14.9 3.1 0.014 14.9 2.2 2.0 1 1 1 2 2 2 0 Transposase zinc-binding domain p450 PF00067.17 EMC93362.1 - 2.5e-45 154.8 0.0 3.1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SH3BGR PF04908.10 EMC93364.1 - 5.6e-07 29.4 0.0 6.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EMC93364.1 - 0.00033 20.5 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Aldo_ket_red PF00248.16 EMC93365.1 - 4.6e-46 156.9 0.0 5.6e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.16 EMC93366.1 - 2.4e-41 141.0 1.3 2.4e-41 141.0 0.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Tim17 PF02466.14 EMC93367.1 - 2.4e-26 92.2 0.2 3.6e-26 91.7 0.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pro-kuma_activ PF09286.6 EMC93369.1 - 2.8e-48 163.5 0.4 8.2e-47 158.8 0.1 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMC93369.1 - 6.3e-06 25.5 2.6 1.1e-05 24.7 1.8 1.5 1 0 0 1 1 1 1 Subtilase family TEA PF01285.13 EMC93369.1 - 0.0036 16.5 0.1 0.0053 15.9 0.1 1.2 1 0 0 1 1 1 1 TEA/ATTS domain family Sigma70_r4 PF04545.11 EMC93369.1 - 0.11 11.7 0.2 3.7 6.9 0.0 2.6 3 0 0 3 3 3 0 Sigma-70, region 4 CBFB_NFYA PF02045.10 EMC93373.1 - 3.6e-31 107.4 4.3 3.6e-31 107.4 3.0 1.7 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 EMC93373.1 - 0.037 12.9 0.1 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein Ribosomal_L37 PF08561.5 EMC93374.1 - 1.5e-10 40.5 4.4 8.4e-08 31.6 3.1 3.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 WD40 PF00400.27 EMC93376.1 - 5.5e-14 51.4 1.0 0.033 14.0 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Abhydro_lipase PF04083.11 EMC93378.1 - 8.6e-18 63.4 0.0 3e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EMC93378.1 - 8.4e-08 32.3 1.1 2.4e-07 30.8 0.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93378.1 - 4.2e-06 26.4 0.2 9.6e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93378.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chloroplast_duf PF14476.1 EMC93378.1 - 0.1 11.3 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 Petal formation-expressed DUF900 PF05990.7 EMC93378.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) AAA PF00004.24 EMC93380.1 - 4.7e-46 156.2 0.0 9.6e-43 145.5 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC93380.1 - 7.4e-05 22.8 1.7 0.022 14.7 0.0 3.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMC93380.1 - 8.3e-05 22.7 0.1 0.0096 16.0 0.0 3.7 3 1 1 4 4 3 1 AAA domain AAA_25 PF13481.1 EMC93380.1 - 0.00011 21.7 0.0 0.00074 18.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC93380.1 - 0.00018 20.6 0.0 0.00056 19.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMC93380.1 - 0.00033 21.4 0.7 0.0013 19.5 0.0 2.4 3 0 0 3 3 1 1 AAA domain Parvo_NS1 PF01057.12 EMC93380.1 - 0.00049 19.0 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.9 EMC93380.1 - 0.0018 18.2 0.0 0.0075 16.1 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EMC93380.1 - 0.0025 17.2 1.3 0.0029 17.0 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMC93380.1 - 0.003 17.2 0.1 0.022 14.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EMC93380.1 - 0.0033 17.5 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 EMC93380.1 - 0.0048 15.6 0.1 0.01 14.5 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 EMC93380.1 - 0.013 15.2 0.0 0.062 13.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMC93380.1 - 0.015 15.2 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EMC93380.1 - 0.021 13.9 0.5 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EMC93380.1 - 0.022 13.8 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EMC93380.1 - 0.031 14.5 0.0 0.094 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EMC93380.1 - 0.048 12.8 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EMC93380.1 - 0.086 12.3 0.0 2.5 7.5 0.0 3.0 4 0 0 4 4 3 0 Sigma-54 interaction domain UPF0079 PF02367.12 EMC93380.1 - 0.087 12.4 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EMC93380.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC93380.1 - 0.11 12.1 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EMC93380.1 - 0.21 10.1 0.0 0.32 9.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase p450 PF00067.17 EMC93381.1 - 8.6e-93 311.3 0.0 1e-92 311.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-3_zeta PF05091.7 EMC93382.1 - 1.1e-185 618.1 0.0 1.3e-185 617.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Abhydrolase_3 PF07859.8 EMC93384.1 - 3.5e-42 144.3 0.0 5e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93384.1 - 4.3e-07 29.7 0.0 6.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMC93384.1 - 0.0045 17.2 0.0 0.0065 16.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 EMC93384.1 - 0.15 11.2 0.0 0.45 9.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMC93385.1 - 2.3e-58 197.2 0.1 3.1e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMC93385.1 - 2.6e-12 46.0 0.0 3.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EMC93385.1 - 1.2e-07 31.5 0.1 5.1e-07 29.5 0.0 1.7 1 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC93385.1 - 0.0022 17.2 0.3 0.14 11.3 0.1 2.8 2 1 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 EMC93385.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain CBM_X PF06204.6 EMC93385.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative carbohydrate binding domain adh_short_C2 PF13561.1 EMC93386.1 - 2.7e-27 96.0 0.0 3.6e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC93386.1 - 1.6e-23 83.4 0.9 2.1e-23 83.0 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93386.1 - 6.8e-08 32.3 0.2 2e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC93386.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 EMC93388.1 - 1.9e-23 82.9 0.0 2.5e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93388.1 - 1.9e-10 40.2 0.0 3.2e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 EMC93389.1 - 8.8e-38 127.4 7.1 1.1e-13 50.3 0.3 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EMC93389.1 - 4.4e-36 122.3 0.0 7.5e-36 121.6 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EMC93389.1 - 2.3e-35 119.9 7.2 1.5e-13 50.1 0.2 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EMC93389.1 - 2.1e-20 71.9 0.0 6.3e-08 31.9 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 EMC93389.1 - 0.0017 18.5 2.6 0.31 11.2 0.2 3.4 3 0 0 3 3 3 1 Bacterial SH3 domain DUF1720 PF08226.6 EMC93389.1 - 0.0025 17.8 48.9 0.0025 17.8 33.9 8.4 2 1 4 6 6 6 3 Domain of unknown function (DUF1720) Na_Ala_symp PF01235.12 EMC93390.1 - 0.12 10.9 0.4 0.13 10.8 0.3 1.0 1 0 0 1 1 1 0 Sodium:alanine symporter family UCR_Fe-S_N PF10399.4 EMC93390.1 - 0.55 9.4 3.5 1.4 8.1 2.4 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SUI1 PF01253.17 EMC93392.1 - 4.9e-24 83.9 0.1 8.7e-24 83.1 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 HrpA_pilin PF09589.5 EMC93392.1 - 0.035 14.5 1.8 0.056 13.8 1.2 1.3 1 0 0 1 1 1 0 HrpA pilus formation protein Fib_alpha PF08702.5 EMC93392.1 - 0.037 14.1 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pkinase PF00069.20 EMC93393.1 - 1.7e-47 161.8 0.0 2.4e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93393.1 - 1.5e-19 70.1 0.0 2.5e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC93393.1 - 0.00027 20.0 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC93393.1 - 0.00082 18.7 0.2 0.0031 16.8 0.0 1.9 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 EMC93393.1 - 0.0052 15.8 0.1 0.0084 15.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC93393.1 - 0.016 14.9 0.1 0.33 10.6 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Shisa PF13908.1 EMC93394.1 - 0.0023 18.1 0.2 0.0031 17.7 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Draxin PF15550.1 EMC93394.1 - 0.026 14.2 0.1 0.031 13.9 0.1 1.1 1 0 0 1 1 1 0 Draxin Cytochrom_C_asm PF01578.15 EMC93394.1 - 0.027 14.0 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein DUF898 PF05987.8 EMC93394.1 - 0.05 12.4 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Auxin_repressed PF05564.7 EMC93394.1 - 0.066 13.8 1.3 0.11 13.1 0.9 1.4 1 0 0 1 1 1 0 Dormancy/auxin associated protein OppC_N PF12911.2 EMC93394.1 - 0.52 9.7 3.8 0.24 10.8 0.5 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Mito_carr PF00153.22 EMC93395.1 - 8.1e-65 214.5 0.6 3.2e-21 74.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.11 EMC93396.1 - 4.3e-54 183.9 0.7 6.8e-54 183.2 0.5 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CorA PF01544.13 EMC93399.1 - 0.017 14.1 0.1 0.017 14.1 0.0 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein COesterase PF00135.23 EMC93400.1 - 2e-58 198.4 0.0 2.9e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC93400.1 - 1.9e-09 37.4 0.0 7.3e-09 35.5 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93400.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 EMC93400.1 - 0.11 11.0 0.0 1.3 7.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EMC93400.1 - 0.17 11.0 0.1 0.35 10.0 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1772 PF08592.6 EMC93401.1 - 3e-18 65.8 3.5 3.7e-18 65.5 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF3099 PF11298.3 EMC93401.1 - 0.69 9.6 2.8 0.57 9.9 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) WD40 PF00400.27 EMC93402.1 - 1.7e-17 62.5 11.0 9e-08 31.7 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 EMC93403.1 - 1.4e-20 73.0 0.7 1.8e-20 72.6 0.5 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF2587 PF10759.4 EMC93403.1 - 0.038 13.3 0.3 0.054 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF3818 PF12825.2 EMC93404.1 - 1.2e-124 415.3 0.0 1.7e-124 414.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EMC93404.1 - 1.5e-42 144.4 1.4 3.4e-42 143.2 1.0 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EMC93404.1 - 2.1e-11 43.5 2.4 2.4e-10 40.2 0.4 3.1 2 1 0 2 2 2 1 PX domain Mito_carr PF00153.22 EMC93405.1 - 4.1e-64 212.3 0.1 1.4e-23 82.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 EMC93406.1 - 2.5e-36 124.1 28.7 3e-36 123.9 19.9 1.0 1 0 0 1 1 1 1 Cgr1 family SprA-related PF12118.3 EMC93406.1 - 0.15 11.3 14.5 0.15 11.3 10.1 1.0 1 0 0 1 1 1 0 SprA-related family PRP1_N PF06424.7 EMC93406.1 - 0.57 10.5 12.3 0.65 10.3 8.5 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Adeno_VII PF03228.9 EMC93406.1 - 0.91 10.1 13.8 1.2 9.6 9.6 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII GAGA_bind PF06217.7 EMC93406.1 - 3.2 7.6 14.3 3.4 7.5 9.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family AIF_C PF14721.1 EMC93406.1 - 5.2 7.3 8.2 7 6.9 5.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4407 PF14362.1 EMC93406.1 - 6.6 5.5 8.8 7.7 5.3 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.12 EMC93406.1 - 8.1 6.1 8.5 8.7 6.0 5.9 1.1 1 0 0 1 1 1 0 DDHD domain adh_short PF00106.20 EMC93410.1 - 2e-22 79.8 1.9 8.7e-14 51.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMC93410.1 - 1.6e-18 67.3 0.1 3.9e-17 62.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC93410.1 - 7.5e-09 35.4 0.8 3.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMC93410.1 - 0.03 14.3 0.3 0.2 11.6 0.2 2.3 2 1 0 2 2 2 0 NADH(P)-binding Pyr_redox PF00070.22 EMC93410.1 - 0.045 14.1 1.5 0.073 13.4 0.2 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMC93410.1 - 0.067 12.8 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain A_deaminase PF00962.17 EMC93411.1 - 3.9e-112 374.4 0.3 5.2e-112 374.0 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Mt_ATP-synt_B PF05405.9 EMC93412.1 - 6.9e-50 168.6 5.0 8.5e-50 168.3 3.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Dak2 PF02734.12 EMC93412.1 - 0.14 11.7 0.9 0.53 9.9 0.6 2.0 1 1 0 1 1 1 0 DAK2 domain CBF PF03914.12 EMC93413.1 - 8.2e-47 158.7 0.2 2.4e-46 157.1 0.0 1.8 2 0 0 2 2 2 1 CBF/Mak21 family Luteo_PO PF04662.8 EMC93413.1 - 0.056 12.9 0.1 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Luteovirus P0 protein RTTN_N PF14726.1 EMC93413.1 - 0.069 13.7 0.3 8.7 6.9 0.0 3.2 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Utp12 PF04003.7 EMC93413.1 - 0.11 12.3 0.8 0.71 9.7 0.2 2.6 2 1 0 2 2 2 0 Dip2/Utp12 Family Lipase PF00151.14 EMC93417.1 - 0.097 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Lipase Rad17 PF03215.10 EMC93418.1 - 1.1e-55 189.3 0.0 1.3e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EMC93418.1 - 2.3e-05 24.0 0.0 5.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EMC93418.1 - 0.0052 16.9 0.1 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMC93418.1 - 0.019 14.5 0.4 0.04 13.5 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EMC93418.1 - 0.026 14.7 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EMC93418.1 - 0.046 13.3 0.1 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EMC93418.1 - 0.07 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EMC93418.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus 2OG-FeII_Oxy_2 PF13532.1 EMC93419.1 - 5.1e-28 98.2 0.0 7.7e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMC93419.1 - 4.7e-05 23.5 0.0 8.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Candida_ALS PF05792.8 EMC93420.1 - 9.6 6.4 7.2 1.5e+02 2.6 5.0 2.3 1 1 0 1 1 1 0 Candida agglutinin-like (ALS) ArfGap PF01412.13 EMC93421.1 - 0.0096 15.6 1.7 0.012 15.3 1.2 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zn_Tnp_IS91 PF14319.1 EMC93421.1 - 0.25 10.8 3.6 0.11 11.9 0.8 1.8 1 1 0 1 1 1 0 Transposase zinc-binding domain NDUFB10 PF10249.4 EMC93422.1 - 0.00017 21.7 0.1 0.00019 21.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EMC93422.1 - 0.037 14.4 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 HWE histidine kinase BRO1 PF03097.13 EMC93423.1 - 1.1e-06 27.7 0.0 1.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain AA_permease_2 PF13520.1 EMC93424.1 - 2e-56 191.3 53.6 2.5e-56 191.0 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC93424.1 - 6.3e-14 51.1 40.5 9.4e-14 50.6 28.1 1.3 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.21 EMC93425.1 - 1.1e-19 70.2 0.1 1.9e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.11 EMC93425.1 - 0.017 14.3 0.1 0.099 11.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein TrkA_N PF02254.13 EMC93425.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 EMC93428.1 - 9.6e-39 133.2 0.6 1.2e-38 132.9 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC93428.1 - 5.3e-06 26.3 1.6 8e-06 25.7 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMC93428.1 - 0.0076 16.0 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMC93428.1 - 0.0085 16.1 0.2 0.02 14.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC93428.1 - 0.0094 15.0 0.0 0.042 12.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC93428.1 - 0.01 15.7 0.4 0.026 14.4 0.0 1.9 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC93428.1 - 0.022 13.6 0.3 0.1 11.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EMC93428.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 EMC93429.1 - 5.4e-67 226.3 30.1 6.3e-67 226.0 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC93429.1 - 1.9e-17 63.0 47.0 3.4e-12 45.7 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 EMC93429.1 - 0.33 11.2 5.6 0.083 13.1 0.5 2.3 2 0 0 2 2 2 0 Divalent cation transporter 2-Hacid_dh_C PF02826.14 EMC93430.1 - 3.2e-52 176.2 0.0 4.1e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC93430.1 - 2.5e-16 59.3 0.0 2.9e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC93430.1 - 4.8e-06 26.5 0.1 1e-05 25.4 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Asp_Glu_race PF01177.17 EMC93431.1 - 1.3e-06 28.5 0.0 3.9e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Aldolase_II PF00596.16 EMC93432.1 - 1.3e-47 161.7 0.0 1.8e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1338 PF07063.8 EMC93433.1 - 7.4e-77 258.3 0.0 8.8e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Glyoxalase PF00903.20 EMC93433.1 - 0.046 13.7 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMC93433.1 - 0.073 13.0 0.1 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.13 EMC93434.1 - 8.3e-32 110.0 0.0 1.5e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93434.1 - 6.4e-08 32.3 8.1 1.4e-07 31.3 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EMC93435.1 - 4e-66 222.8 0.0 5.8e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93435.1 - 6e-35 120.5 0.0 1.2e-34 119.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMC93435.1 - 3e-10 40.0 0.8 1.7e-09 37.6 0.0 2.6 3 0 0 3 3 3 1 FHA domain Kinase-like PF14531.1 EMC93435.1 - 5.5e-05 22.2 0.0 0.00027 20.0 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Lact-deh-memb PF09330.6 EMC93435.1 - 0.051 12.9 0.1 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Pyr_redox_3 PF13738.1 EMC93437.1 - 1.5e-19 70.8 0.0 2.4e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC93437.1 - 5.2e-13 48.0 0.8 4.9e-11 41.5 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMC93437.1 - 3.8e-11 42.8 0.2 2.1e-08 34.0 0.1 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC93437.1 - 5.5e-07 29.6 0.0 0.0099 15.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC93437.1 - 1.5e-05 24.8 1.2 0.063 13.0 0.2 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMC93437.1 - 2.7e-05 23.2 0.0 0.00035 19.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMC93437.1 - 0.0004 19.4 2.0 0.075 11.9 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC93437.1 - 0.00057 20.2 2.3 0.048 14.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC93437.1 - 0.0015 17.5 0.1 0.13 11.0 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_10 PF13460.1 EMC93437.1 - 0.0045 17.0 0.3 0.065 13.2 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Thi4 PF01946.12 EMC93437.1 - 0.0081 15.2 0.5 0.14 11.2 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EMC93437.1 - 0.0085 14.9 0.3 0.032 13.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 EMC93437.1 - 0.019 14.4 0.1 4.8 6.6 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA DUF3591 PF12157.3 EMC93438.1 - 1.5e-164 547.7 4.7 2.1e-164 547.2 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EMC93438.1 - 0.0023 17.5 1.8 0.0069 16.0 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EMC93438.1 - 0.015 15.2 0.9 0.027 14.3 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle VirB8 PF04335.8 EMC93439.1 - 0.71 9.4 3.6 4.3 6.8 2.5 2.1 1 1 0 1 1 1 0 VirB8 protein FtsX PF02687.16 EMC93439.1 - 0.9 9.3 5.1 1.1 9.0 0.6 2.2 2 0 0 2 2 2 0 FtsX-like permease family Peptidase_S28 PF05577.7 EMC93440.1 - 1.1e-44 152.8 6.5 1.9e-43 148.6 4.5 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Sec10 PF07393.6 EMC93441.1 - 6.5e-203 675.8 0.0 8.7e-203 675.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Sugarporin_N PF11471.3 EMC93442.1 - 0.034 13.8 9.2 0.24 11.0 0.0 3.7 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF465 PF04325.8 EMC93442.1 - 0.04 13.6 1.6 0.3 10.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF465) DUF4140 PF13600.1 EMC93442.1 - 5.9 7.3 9.1 0.64 10.5 0.1 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fmp27_WPPW PF10359.4 EMC93442.1 - 6.2 5.1 8.7 1.2 7.4 0.5 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain adh_short_C2 PF13561.1 EMC93443.1 - 2.1e-17 63.6 0.0 2.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC93443.1 - 5.9e-16 58.8 0.0 1.5e-15 57.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93443.1 - 5e-07 29.5 0.0 2.1e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMC93443.1 - 0.00021 21.3 0.0 0.052 13.5 0.0 2.8 2 1 0 2 2 2 1 NADH(P)-binding SnoaL_2 PF12680.2 EMC93444.1 - 0.017 15.5 0.0 0.029 14.7 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 EMC93444.1 - 0.061 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) PIR PF00399.14 EMC93445.1 - 0.00041 19.6 4.7 0.0032 16.7 3.2 2.7 1 0 0 1 1 1 1 Yeast PIR protein repeat Sugar_tr PF00083.19 EMC93447.1 - 7.4e-24 84.1 24.2 2.7e-21 75.6 16.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2333 PF10095.4 EMC93447.1 - 0.14 10.8 0.0 0.36 9.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) HSCB_C PF07743.8 EMC93449.1 - 2.3e-18 66.4 2.5 2.3e-18 66.4 1.7 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EMC93449.1 - 2.6e-12 46.2 0.7 4.4e-12 45.5 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain Med5 PF08689.5 EMC93449.1 - 0.047 11.3 0.2 0.063 10.9 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 dCMP_cyt_deam_1 PF00383.17 EMC93450.1 - 1e-15 57.2 1.6 1.3e-15 56.8 1.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EMC93450.1 - 9e-12 45.0 0.8 5.2e-10 39.3 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EMC93450.1 - 0.0091 15.3 3.5 0.63 9.3 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF2407_C PF13373.1 EMC93451.1 - 0.026 14.4 1.6 2.4 8.0 0.0 2.5 1 1 0 2 2 2 0 DUF2407 C-terminal domain DUF3708 PF12501.3 EMC93451.1 - 1 9.1 6.9 0.24 11.2 0.2 2.4 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter THF_DHG_CYH PF00763.18 EMC93452.1 - 5.7e-17 61.8 0.0 8.2e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EMC93452.1 - 3.5e-13 48.9 0.0 4e-09 35.7 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EMC93452.1 - 0.11 12.6 0.0 3.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MMS19_N PF14500.1 EMC93453.1 - 2.2e-78 263.1 2.0 2.8e-77 259.5 0.0 3.5 3 2 2 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EMC93453.1 - 4.4e-59 200.2 1.0 2.9e-57 194.2 0.0 3.0 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EMC93453.1 - 0.036 14.3 0.8 0.036 14.3 0.6 6.0 4 4 1 5 5 5 0 HEAT repeats Sec3_C_2 PF15278.1 EMC93453.1 - 0.052 13.6 0.4 1.8 8.7 0.1 2.7 2 0 0 2 2 2 0 Sec3 exocyst complex subunit SH3_9 PF14604.1 EMC93454.1 - 2.9e-32 110.0 1.5 7.1e-16 57.5 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMC93454.1 - 2.9e-29 100.1 3.6 5.3e-14 51.3 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EMC93454.1 - 8.3e-16 57.2 0.4 1.1e-07 31.2 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EMC93454.1 - 5.4e-11 42.4 0.0 9.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box PF00646.28 EMC93455.1 - 0.00031 20.2 0.0 0.00065 19.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC93455.1 - 0.00059 19.5 0.2 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like DND1_DSRM PF14709.1 EMC93458.1 - 0.00025 21.2 0.0 0.00063 19.9 0.0 1.6 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EMC93458.1 - 0.013 16.0 0.1 0.037 14.6 0.0 1.8 1 1 0 1 1 1 0 Double-stranded RNA binding motif Xan_ur_permease PF00860.15 EMC93459.1 - 6.4e-68 229.0 32.8 1.3e-66 224.7 22.7 2.0 1 1 0 1 1 1 1 Permease family Nairo_nucleo PF02477.10 EMC93459.1 - 0.19 10.4 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein Dak1 PF02733.12 EMC93460.1 - 3.6e-88 295.2 0.0 4.1e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain Methyltransf_16 PF10294.4 EMC93461.1 - 2.1e-13 50.0 0.0 1.8e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Pribosyltran PF00156.22 EMC93462.1 - 3.8e-15 55.7 0.2 1.3e-14 54.0 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AMP-binding PF00501.23 EMC93463.1 - 1.1e-79 267.7 0.0 1.6e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC93463.1 - 8.2e-05 23.4 0.0 0.00034 21.4 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECM11 PF15463.1 EMC93464.1 - 3.7e-30 105.0 0.1 3.7e-30 105.0 0.1 2.5 3 0 0 3 3 3 1 Extracellular mutant protein 11 F-box-like PF12937.2 EMC93465.1 - 7.5e-05 22.3 2.7 0.0001 21.9 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMC93465.1 - 0.0062 16.1 0.2 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain DUF718 PF05336.8 EMC93466.1 - 1.7e-34 117.8 0.2 1.9e-34 117.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) FSA_C PF10479.4 EMC93466.1 - 0.035 12.1 0.0 0.039 12.0 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-C2H2 PF00096.21 EMC93468.1 - 3.1e-08 33.4 13.5 0.0011 19.1 2.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC93468.1 - 2.4e-07 30.6 26.0 1.1e-05 25.4 2.3 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC93468.1 - 8.2e-06 25.7 12.7 0.013 15.7 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC93468.1 - 0.52 10.5 3.2 0.26 11.4 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Methyltransf_2 PF00891.13 EMC93470.1 - 1.9e-26 92.7 0.0 2.5e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase HTH_IclR PF09339.5 EMC93470.1 - 0.00018 21.0 0.0 0.00046 19.7 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.15 EMC93470.1 - 0.061 13.4 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator HTH_5 PF01022.15 EMC93470.1 - 0.09 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Hist_deacetyl PF00850.14 EMC93471.1 - 3e-64 217.2 0.4 9.7e-64 215.5 0.3 1.8 1 1 0 1 1 1 1 Histone deacetylase domain Peptidase_M76 PF09768.4 EMC93472.1 - 1.8e-64 216.3 0.5 2.2e-64 216.0 0.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EMC93472.1 - 0.0077 15.9 1.1 0.0077 15.9 0.8 2.5 2 2 0 2 2 2 1 SprT-like family Tox-MPTase2 PF15638.1 EMC93472.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Peptidase_M91 PF14891.1 EMC93472.1 - 0.18 11.8 0.2 0.27 11.3 0.1 1.2 1 0 0 1 1 1 0 Effector protein Pkinase PF00069.20 EMC93473.1 - 3.3e-68 229.6 0.0 4.1e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93473.1 - 1.5e-42 145.4 0.0 2.1e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC93473.1 - 4.7e-06 25.7 0.0 3.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC93473.1 - 0.0008 18.5 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC93473.1 - 0.025 13.9 0.1 0.055 12.7 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M3 PF01432.15 EMC93474.1 - 1.2e-155 519.0 0.0 2.5e-155 518.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M3 Rhodanese PF00581.15 EMC93475.1 - 4.9e-12 46.1 0.0 7e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain MR_MLE_C PF13378.1 EMC93477.1 - 7.1e-19 67.8 0.1 1.8e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EMC93477.1 - 1.9e-13 50.7 0.0 5.2e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 EMC93477.1 - 0.00083 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.11 EMC93477.1 - 0.12 12.3 0.1 0.82 9.6 0.0 2.3 3 0 0 3 3 3 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain GFA PF04828.9 EMC93478.1 - 5.4e-13 48.7 0.0 7.1e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Lon_C PF05362.8 EMC93479.1 - 2.8e-63 212.9 0.0 6.1e-63 211.8 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EMC93479.1 - 5.3e-36 124.2 0.0 1.4e-35 122.8 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EMC93479.1 - 7.9e-22 77.8 0.0 2.1e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC93479.1 - 5.4e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMC93479.1 - 2.2e-06 27.6 0.0 6.9e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EMC93479.1 - 2e-05 24.0 0.0 4.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EMC93479.1 - 3.4e-05 24.0 0.1 0.00061 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EMC93479.1 - 4.1e-05 22.4 0.0 8.3e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 EMC93479.1 - 0.00013 22.8 0.0 0.00063 20.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC93479.1 - 0.00014 21.0 0.0 0.00084 18.4 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMC93479.1 - 0.00021 21.3 0.1 0.0021 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMC93479.1 - 0.0038 17.1 0.0 0.0096 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EMC93479.1 - 0.0048 16.7 0.1 0.18 11.6 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.1 EMC93479.1 - 0.0061 16.8 1.5 0.088 13.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 EMC93479.1 - 0.03 13.7 0.1 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 EMC93479.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMC93479.1 - 0.061 13.0 0.1 0.65 9.6 0.0 2.5 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 EMC93479.1 - 0.074 13.2 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EMC93479.1 - 0.076 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EMC93479.1 - 0.079 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EMC93479.1 - 0.093 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 EMC93479.1 - 2.3 8.5 5.8 0.67 10.2 0.0 2.7 3 0 0 3 3 3 0 ABC transporter eIF3g PF12353.3 EMC93480.1 - 1.7e-38 131.4 2.2 2.3e-38 130.9 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EMC93480.1 - 3.3e-17 61.8 0.0 5.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC93480.1 - 6.5e-13 48.4 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC93480.1 - 4.1e-07 29.7 0.0 6.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M3 PF09213.5 EMC93482.1 - 0.092 11.2 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 M3 Fungal_trans_2 PF11951.3 EMC93483.1 - 1.5e-09 36.9 1.3 2.3e-09 36.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93483.1 - 1.3e-05 25.0 10.9 2.1e-05 24.3 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EMC93484.1 - 6.1e-11 42.0 0.9 2.6e-10 40.0 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC93484.1 - 5.6e-09 35.6 0.1 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FA_desaturase PF00487.19 EMC93485.1 - 2.1e-19 70.0 10.2 2.1e-19 70.0 7.1 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMC93485.1 - 1.4e-15 56.8 0.0 3.7e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_12 PF13087.1 EMC93486.1 - 1.6e-22 79.8 0.0 2.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EMC93486.1 - 5.2e-05 23.3 0.0 9.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 EMC93486.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EMC93487.1 - 0.00086 18.5 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 EMC93487.1 - 0.00099 19.1 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EMC93487.1 - 0.0015 18.2 0.1 0.0032 17.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMC93487.1 - 0.0028 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC93487.1 - 0.027 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EMC93487.1 - 0.028 14.5 0.2 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EMC93487.1 - 0.037 13.9 0.2 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMC93487.1 - 0.06 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 EMC93487.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 EMC93487.1 - 0.097 13.4 0.0 0.28 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMC93487.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 KaiC PIF1 PF05970.9 EMC93487.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.4 EMC93487.1 - 0.15 10.9 0.1 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EMC93487.1 - 0.17 12.2 0.0 0.46 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Dehydrin PF00257.14 EMC93488.1 - 0.068 13.4 1.1 4.2 7.6 0.8 2.3 2 0 0 2 2 2 0 Dehydrin Fungal_trans_2 PF11951.3 EMC93489.1 - 7.7e-17 60.9 0.2 7.2e-11 41.3 0.7 3.0 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93489.1 - 1.2e-07 31.5 12.5 2.3e-07 30.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EMC93490.1 - 1.2e-36 126.1 0.0 1.4e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC93490.1 - 3.1e-11 43.6 0.3 3.4e-11 43.4 0.2 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC93490.1 - 0.0006 19.3 0.1 0.00066 19.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMC93490.1 - 0.00068 19.5 2.5 0.0009 19.1 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EMC93490.1 - 0.0024 17.8 0.1 0.0036 17.2 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EMC93490.1 - 0.0075 15.0 0.0 0.0088 14.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EMC93490.1 - 0.017 14.0 0.2 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 EMC93490.1 - 0.039 14.3 1.2 0.074 13.4 0.8 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_S28e PF01200.13 EMC93490.1 - 0.13 11.9 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S28e DapB_N PF01113.15 EMC93490.1 - 0.15 11.9 0.1 0.32 10.9 0.2 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Halogen_Hydrol PF10112.4 EMC93491.1 - 0.14 11.5 0.1 0.34 10.3 0.1 1.5 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PGI PF00342.14 EMC93492.1 - 5.7e-219 727.5 0.5 6.5e-219 727.3 0.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Abhydrolase_6 PF12697.2 EMC93494.1 - 6.4e-28 98.1 0.1 7.8e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93494.1 - 5.8e-13 48.9 0.1 2.6e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93494.1 - 1.7e-12 47.3 0.0 2.2e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC93494.1 - 1.1e-08 34.8 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EMC93494.1 - 0.00041 19.6 0.0 0.0095 15.1 0.0 2.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMC93494.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EMC93494.1 - 0.014 14.2 0.0 0.027 13.2 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.8 EMC93494.1 - 0.033 13.7 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Pkinase PF00069.20 EMC93495.1 - 7e-71 238.4 0.0 8.9e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93495.1 - 6.7e-34 117.1 0.0 9.3e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMC93495.1 - 6.6e-11 42.5 0.3 2.9e-10 40.4 0.2 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC93495.1 - 0.00067 18.6 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ZZ PF00569.12 EMC93496.1 - 2.9e-11 42.7 4.6 5.6e-11 41.8 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EMC93496.1 - 3.3e-06 27.0 0.1 1.1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.12 EMC93496.1 - 0.00076 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain DUF4615 PF15393.1 EMC93496.1 - 6.8 6.9 8.3 0.48 10.6 1.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4615) adh_short PF00106.20 EMC93498.1 - 2.8e-23 82.6 0.1 4.2e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC93498.1 - 1.2e-12 48.1 0.0 1.8e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC93498.1 - 9.8e-07 28.6 0.1 1.6e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMC93498.1 - 0.0011 17.9 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMC93498.1 - 0.0013 18.8 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMC93498.1 - 0.025 14.7 0.0 0.055 13.5 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EMC93498.1 - 0.04 13.5 0.1 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMC93498.1 - 0.092 13.1 0.1 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Erg28 PF03694.8 EMC93499.1 - 1.1e-38 131.6 0.0 1.3e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Erg28 like protein DHO_dh PF01180.16 EMC93500.1 - 1.2e-71 241.1 0.1 1.4e-71 240.9 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EMC93500.1 - 0.0027 16.9 0.7 0.94 8.6 0.0 2.7 3 0 0 3 3 3 2 PcrB family FMN_dh PF01070.13 EMC93500.1 - 0.0047 15.8 0.1 0.36 9.6 0.2 2.5 2 1 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.10 EMC93500.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Transketolase_N PF00456.16 EMC93501.1 - 4.1e-124 413.7 0.0 7e-124 412.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMC93501.1 - 5.4e-36 123.7 0.1 1.2e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EMC93501.1 - 2.5e-07 29.9 0.0 3.7e-05 22.7 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EMC93501.1 - 4.8e-07 28.7 0.2 9.2e-07 27.8 0.1 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 EMC93501.1 - 2.1e-06 27.6 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain NAD_binding_11 PF14833.1 EMC93502.1 - 8.2e-36 122.7 1.9 8.9e-25 87.1 0.2 2.6 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EMC93502.1 - 2e-16 60.2 0.0 4.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RTA1 PF04479.8 EMC93503.1 - 6.5e-41 140.2 2.0 1e-40 139.6 1.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Poxvirus_B22R_C PF13168.1 EMC93503.1 - 0.14 11.3 0.2 0.23 10.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Dak2 PF02734.12 EMC93504.1 - 1.4e-45 155.0 4.4 2e-45 154.5 1.4 2.1 2 0 0 2 2 2 1 DAK2 domain OsmC PF02566.14 EMC93505.1 - 1.5e-14 54.0 0.0 4e-14 52.6 0.0 1.7 1 1 1 2 2 2 1 OsmC-like protein Fungal_trans PF04082.13 EMC93507.1 - 9e-15 54.2 0.1 1.8e-14 53.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EMC93507.1 - 1.7e-07 31.2 9.9 9.5e-05 22.5 2.6 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC93507.1 - 1.4e-05 25.0 16.3 0.00043 20.4 4.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EMC93507.1 - 0.0013 18.8 4.7 0.0028 17.7 3.2 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EMC93507.1 - 0.0096 16.2 19.6 0.041 14.2 4.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.2 EMC93507.1 - 0.24 11.2 2.3 0.46 10.3 1.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_jaz PF12171.3 EMC93507.1 - 0.27 11.4 6.7 0.13 12.4 0.7 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EMC93507.1 - 4.2 7.2 11.0 0.51 10.1 0.9 2.6 2 0 0 2 2 2 0 BED zinc finger BIR PF00653.16 EMC93508.1 - 0.0088 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 EMC93508.1 - 0.048 13.4 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 C3HC zinc finger-like SLAC1 PF03595.12 EMC93509.1 - 2.8e-79 266.1 44.1 3.1e-79 266.0 30.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Phosphodiest PF01663.17 EMC93510.1 - 2.8e-81 273.6 0.0 3.7e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMC93510.1 - 4.3e-05 22.8 0.0 0.045 12.9 0.0 2.3 2 0 0 2 2 2 2 Sulfatase Herpes_US9 PF06072.6 EMC93510.1 - 0.033 14.0 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3379 PF11859.3 EMC93510.1 - 0.054 12.6 0.0 0.083 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) CDC45 PF02724.9 EMC93510.1 - 0.29 9.0 1.1 0.4 8.6 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.24 EMC93511.1 - 1.2e-40 138.7 0.0 2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC93511.1 - 5e-06 26.6 0.0 0.0006 19.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMC93511.1 - 2.7e-05 23.9 0.1 0.0003 20.5 0.0 2.8 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC93511.1 - 0.00026 21.0 0.0 0.0013 18.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EMC93511.1 - 0.00037 20.4 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMC93511.1 - 0.0018 17.2 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMC93511.1 - 0.004 17.9 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC93511.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMC93511.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EMC93511.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMC93511.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC93511.1 - 0.031 14.4 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EMC93511.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4164 PF13747.1 EMC93511.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) AAA_3 PF07726.6 EMC93511.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EMC93511.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EMC93511.1 - 0.098 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMC93511.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMC93511.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.19 EMC93512.1 - 1.3e-130 436.2 1.2 1.6e-130 435.9 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EMC93512.1 - 0.0029 17.0 0.0 0.0089 15.4 0.0 1.8 1 0 0 1 1 1 1 Phage Tail Protein X DeoC PF01791.4 EMC93512.1 - 0.13 11.4 1.3 1.3 8.2 0.1 2.5 3 0 0 3 3 3 0 DeoC/LacD family aldolase DUF1077 PF06417.7 EMC93513.1 - 4.8e-50 168.1 1.0 5.3e-50 167.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Spore_YtrH PF14034.1 EMC93513.1 - 0.025 14.5 0.3 0.033 14.1 0.2 1.1 1 0 0 1 1 1 0 Sporulation protein YtrH Adaptin_N PF01602.15 EMC93514.1 - 3.2e-133 444.8 10.6 4e-133 444.5 7.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMC93514.1 - 3e-18 66.2 2.7 1.5e-17 64.0 0.2 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMC93514.1 - 2.4e-16 59.8 8.2 5.8e-11 42.5 0.4 4.4 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EMC93514.1 - 5e-11 41.7 4.8 0.00033 20.5 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EMC93514.1 - 3e-06 27.5 6.3 0.0099 16.3 0.0 5.9 5 1 1 6 6 6 2 HEAT-like repeat CLASP_N PF12348.3 EMC93514.1 - 6.7e-05 22.3 0.6 0.43 9.8 0.1 3.1 2 1 1 3 3 3 2 CLASP N terminal DNA_alkylation PF08713.6 EMC93514.1 - 0.00068 19.2 0.4 5.5 6.4 0.1 4.0 2 2 1 4 4 4 2 DNA alkylation repair enzyme Atx10homo_assoc PF09759.4 EMC93514.1 - 0.0067 16.1 0.0 6.5 6.5 0.0 4.2 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DUF2435 PF10363.4 EMC93514.1 - 0.075 12.9 4.2 0.84 9.5 0.0 3.8 2 1 1 4 4 4 0 Protein of unknown function (DUF2435) Arm PF00514.18 EMC93514.1 - 0.37 10.6 6.4 50 3.9 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ACPS PF01648.15 EMC93515.1 - 1.2e-14 54.0 0.4 4.4e-14 52.2 0.3 1.9 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily T5orf172 PF10544.4 EMC93517.1 - 5.2e-10 39.6 0.0 1.5e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EMC93517.1 - 3.6e-08 33.7 0.0 1.2e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 Ran_BP1 PF00638.13 EMC93518.1 - 1.8e-15 57.0 0.0 3.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain ArfGap PF01412.13 EMC93519.1 - 8.5e-36 122.2 0.4 1.5e-35 121.4 0.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2415 PF10313.4 EMC93520.1 - 4.7e-14 51.7 0.0 8.5e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EMC93520.1 - 0.00011 21.9 2.4 1 9.3 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.1 EMC93520.1 - 0.055 13.7 2.4 5.3 7.4 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain Lgl_C PF08596.5 EMC93520.1 - 0.19 10.1 0.0 0.58 8.5 0.0 1.8 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal DUF702 PF05142.7 EMC93520.1 - 8 6.6 5.8 22 5.1 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Mannitol_dh_C PF08125.8 EMC93521.1 - 4e-50 170.2 0.2 7.1e-50 169.4 0.2 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EMC93521.1 - 2.2e-18 66.6 1.7 5.1e-18 65.4 0.1 2.1 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EMC93521.1 - 0.00026 20.7 0.3 0.00026 20.7 0.2 2.1 3 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMC93521.1 - 0.012 15.2 0.7 0.02 14.4 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NUMOD3 PF07460.6 EMC93521.1 - 0.071 13.0 0.4 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) Choline_transpo PF04515.7 EMC93522.1 - 6e-104 347.3 19.2 6e-104 347.3 13.3 2.2 2 1 1 3 3 3 1 Plasma-membrane choline transporter tRNA-synt_2 PF00152.15 EMC93523.1 - 1e-72 244.7 0.0 1.7e-72 244.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EMC93523.1 - 5.4e-17 61.5 0.0 7.9e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EMC93523.1 - 4e-08 32.9 0.0 7.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMC93523.1 - 6.5e-05 22.2 0.4 0.32 10.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Prp19 PF08606.6 EMC93523.1 - 3.2 7.5 5.1 3.5 7.4 2.3 2.0 2 0 0 2 2 2 0 Prp19/Pso4-like Acyltransferase PF01553.16 EMC93525.1 - 1.2e-15 57.0 0.0 1.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TF_Zn_Ribbon PF08271.7 EMC93526.1 - 0.0081 15.4 0.5 0.93 8.8 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding AAA_17 PF13207.1 EMC93527.1 - 0.0007 20.4 0.1 0.0032 18.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC93527.1 - 0.0068 16.7 0.0 0.019 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC93527.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EMC93527.1 - 0.014 15.2 0.0 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EMC93527.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PRK PF00485.13 EMC93527.1 - 0.032 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EMC93527.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EMC93527.1 - 0.093 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EMC93527.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EMC93527.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 EMC93527.1 - 0.12 11.1 0.4 0.25 10.0 0.2 1.6 1 1 1 2 2 2 0 ArgK protein ABC_tran PF00005.22 EMC93527.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EMC93527.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EMC93527.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cys_Met_Meta_PP PF01053.15 EMC93528.1 - 9.1e-120 399.4 0.1 2.6e-108 361.7 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.11 EMC93528.1 - 0.017 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EMC93528.1 - 0.054 12.2 0.0 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V adh_short PF00106.20 EMC93529.1 - 1.2e-62 210.7 6.7 3.4e-31 108.4 0.5 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMC93529.1 - 1.1e-32 113.1 0.9 3e-15 56.3 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EMC93529.1 - 4.1e-31 106.9 0.0 1.1e-30 105.5 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain RRM_4 PF10598.4 EMC93529.1 - 0.018 14.9 0.0 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 adh_short PF00106.20 EMC93530.1 - 8.2e-20 71.3 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93530.1 - 7.4e-09 35.5 0.0 1.9e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMC93530.1 - 4.2e-07 29.9 0.0 6.9e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC93530.1 - 7.8e-05 22.2 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EMC93530.1 - 0.00022 21.3 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EMC93530.1 - 0.001 18.0 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMC93530.1 - 0.0011 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EMC93530.1 - 0.017 15.5 0.1 0.036 14.4 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMC93530.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMC93530.1 - 0.062 12.9 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chitin_synth_1 PF01644.12 EMC93531.1 - 6.8e-85 282.8 0.1 1.1e-84 282.2 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMC93531.1 - 4.4e-32 109.5 0.1 9.8e-32 108.4 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMC93531.1 - 7.9e-24 83.9 1.3 9.6e-21 73.7 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMC93531.1 - 4.2e-09 36.4 0.3 4.2e-09 36.4 0.2 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC93531.1 - 1.1e-06 28.6 0.0 4.7e-06 26.5 0.0 1.9 1 1 0 2 2 2 1 Glycosyltransferase like family 2 DUF1772 PF08592.6 EMC93531.1 - 3.5 7.3 7.0 40 3.9 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) EAP30 PF04157.11 EMC93532.1 - 1.5e-53 181.2 0.0 1.9e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EMC93532.1 - 8.9e-28 95.9 0.0 1.4e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 EMC93532.1 - 8.4e-05 21.5 7.2 0.0066 15.5 0.8 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 EMC93532.1 - 0.00021 20.8 5.2 0.0023 17.4 0.1 2.6 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Rubredoxin PF00301.15 EMC93532.1 - 0.0043 16.8 4.5 0.17 11.8 0.1 3.8 4 0 0 4 4 4 1 Rubredoxin GRAM PF02893.15 EMC93532.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 GRAM domain DZR PF12773.2 EMC93532.1 - 0.018 14.8 0.4 0.018 14.8 0.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EMC93532.1 - 9.3 5.8 8.6 14 5.3 0.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain SAC3_GANP PF03399.11 EMC93533.1 - 5.1e-60 202.5 0.2 6.9e-60 202.1 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMC93533.1 - 0.016 15.0 0.1 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 Imm5 PF14423.1 EMC93533.1 - 0.059 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 SH3_1 PF00018.23 EMC93534.1 - 5.3e-23 80.1 0.0 4.5e-11 41.9 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC93534.1 - 9.7e-15 53.8 0.6 1.9e-06 27.3 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EMC93534.1 - 2.9e-13 49.5 0.0 7.9e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EMC93534.1 - 2.4e-11 42.9 0.0 3.5e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain HSP70 PF00012.15 EMC93535.1 - 2.4e-264 877.8 15.3 2.8e-264 877.6 10.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC93535.1 - 1.2e-13 50.3 4.0 2.6e-12 46.0 1.2 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EMC93535.1 - 3.8e-06 26.6 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMC93535.1 - 0.0026 17.6 8.6 0.31 10.8 0.9 4.4 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.15 EMC93535.1 - 0.0027 17.0 0.4 0.12 11.6 0.0 2.6 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DnaG_DnaB_bind PF08278.6 EMC93535.1 - 0.27 11.4 4.5 0.47 10.6 2.2 2.1 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Endotoxin_N PF03945.9 EMC93535.1 - 0.3 10.4 1.3 0.44 9.9 0.3 1.6 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF4363 PF14276.1 EMC93535.1 - 1.6 8.4 4.3 3.5 7.3 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) zf-trcl PF13451.1 EMC93536.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Probable zinc-binding domain Carb_kinase PF01256.12 EMC93537.1 - 4.7e-56 189.7 0.0 5.8e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EMC93537.1 - 0.00044 19.5 0.1 0.0019 17.4 0.1 1.9 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.10 EMC93537.1 - 0.0051 16.0 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Abhydrolase_6 PF12697.2 EMC93539.1 - 3.9e-29 102.1 0.0 4.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93539.1 - 1.8e-15 57.1 0.0 1.1e-13 51.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93539.1 - 3.1e-12 46.4 0.0 4.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC93539.1 - 2.1e-06 27.4 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EMC93539.1 - 0.0055 16.9 0.0 0.0073 16.5 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain FSH1 PF03959.8 EMC93539.1 - 0.027 13.9 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EMC93539.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Kinesin PF00225.18 EMC93541.1 - 7.1e-110 366.8 0.0 1.2e-109 366.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EMC93541.1 - 8.6e-33 112.9 0.1 4.2e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein PH PF00169.24 EMC93541.1 - 1.4e-05 25.2 0.0 0.00017 21.7 0.0 2.7 3 0 0 3 3 3 1 PH domain FHA PF00498.21 EMC93541.1 - 0.00011 22.2 0.1 0.00079 19.5 0.0 2.4 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 EMC93541.1 - 0.028 14.4 0.3 0.063 13.3 0.2 1.7 1 0 0 1 1 1 0 Kinesin protein 1B Met_10 PF02475.11 EMC93542.1 - 8.3e-67 224.6 0.0 1.4e-66 223.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EMC93542.1 - 0.0047 16.9 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cbl_N PF02262.11 EMC93542.1 - 0.074 12.7 0.0 0.43 10.2 0.0 2.2 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 Methyltransf_11 PF08241.7 EMC93543.1 - 1.2e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC93543.1 - 1.7e-06 27.3 0.0 2.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMC93543.1 - 4.1e-06 27.1 0.0 6.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC93543.1 - 3.4e-05 23.4 0.0 6.5e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC93543.1 - 0.00019 21.7 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC93543.1 - 0.0013 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC93543.1 - 0.065 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EMC93543.1 - 0.09 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Beta_elim_lyase PF01212.16 EMC93544.1 - 2.5e-65 220.5 0.0 3.1e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EMC93544.1 - 1.5e-05 23.4 0.0 2.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TCR PF03638.10 EMC93544.1 - 0.17 11.7 0.6 0.34 10.7 0.4 1.4 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain zf-C2H2_4 PF13894.1 EMC93545.1 - 0.00019 21.5 44.6 0.063 13.6 0.3 7.0 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC93545.1 - 0.0016 18.6 44.4 0.32 11.4 5.7 7.1 7 0 0 7 7 7 4 Zinc finger, C2H2 type ELMO_CED12 PF04727.8 EMC93548.1 - 3.9e-41 140.4 0.0 7.1e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family GlyL_C PF12524.3 EMC93548.1 - 0.14 12.1 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal DUF1752 PF08550.5 EMC93549.1 - 1.2e-07 31.2 3.3 2.3e-07 30.2 2.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TLD PF07534.11 EMC93550.1 - 0.089 12.7 0.0 0.095 12.6 0.0 1.1 1 0 0 1 1 1 0 TLD SLAC1 PF03595.12 EMC93551.1 - 0.012 14.2 1.8 0.01 14.4 0.9 1.3 1 1 0 1 1 1 0 Voltage-dependent anion channel HET PF06985.6 EMC93552.1 - 4.7e-25 88.3 0.0 1.4e-24 86.8 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RestrictionSfiI PF11487.3 EMC93552.1 - 0.033 13.3 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI Kelch_3 PF13415.1 EMC93553.1 - 2.3e-33 113.5 5.5 3e-08 33.5 0.0 6.5 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC93553.1 - 4.9e-27 93.4 15.1 2e-14 53.0 0.0 7.3 6 3 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EMC93553.1 - 1.3e-16 59.9 1.1 0.0035 17.4 0.0 6.6 5 2 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EMC93553.1 - 7.6e-15 54.1 3.6 0.026 14.0 0.0 7.2 6 2 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EMC93553.1 - 2.5e-14 52.8 0.1 0.011 15.6 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EMC93553.1 - 5.9e-09 35.3 8.0 0.05 13.3 0.0 6.8 6 2 0 6 6 6 3 Kelch motif GPI-anchored PF10342.4 EMC93554.1 - 6.4e-15 55.4 1.1 6.4e-15 55.4 0.8 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 EMC93554.1 - 3.5e-14 53.0 7.4 3.5e-14 53.0 5.2 2.0 2 1 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 7TM-7TMR_HD PF07698.6 EMC93554.1 - 0.12 11.7 2.6 0.19 11.1 1.6 1.5 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Peptidase_M24 PF00557.19 EMC93555.1 - 1.1e-57 194.9 0.0 1.4e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMC93555.1 - 0.00056 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_A4 PF01828.12 EMC93556.1 - 3.7e-80 267.8 12.7 4.3e-80 267.6 8.8 1.0 1 0 0 1 1 1 1 Peptidase A4 family Mit_ribos_Mrp51 PF11709.3 EMC93559.1 - 1.3e-64 218.4 0.3 3.1e-63 213.8 0.2 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Aconitase PF00330.15 EMC93562.1 - 2.1e-181 603.4 0.0 2.8e-181 603.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMC93562.1 - 1.4e-43 148.1 0.0 3.6e-43 146.8 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Peptidase_M28 PF04389.12 EMC93563.1 - 2.8e-28 98.8 0.1 5.7e-28 97.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMC93563.1 - 9.7e-07 28.4 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SPC25 PF06703.6 EMC93564.1 - 1e-48 164.9 0.0 1.2e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 EMC93565.1 - 1.8e-57 193.5 0.1 2.6e-57 192.9 0.1 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 adh_short PF00106.20 EMC93566.1 - 0.027 14.3 0.3 0.06 13.2 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Med26 PF08711.6 EMC93567.1 - 0.0018 17.7 0.0 0.0064 15.9 0.0 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain LBP_BPI_CETP PF01273.20 EMC93567.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain TPR_11 PF13414.1 EMC93568.1 - 6.1e-23 80.2 10.7 4.4e-11 42.2 0.4 4.8 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EMC93568.1 - 1.5e-21 75.0 2.4 2.6e-07 29.9 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMC93568.1 - 9.4e-20 68.8 5.0 1.3e-05 24.6 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC93568.1 - 2.3e-14 53.5 13.8 2.3e-06 28.1 0.2 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC93568.1 - 1.9e-13 49.1 0.6 0.016 14.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC93568.1 - 2.1e-13 50.0 8.2 3.7e-07 29.9 0.2 4.1 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC93568.1 - 8.1e-12 44.6 14.7 5.4e-05 23.4 0.5 5.9 5 2 2 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC93568.1 - 8.5e-12 45.2 5.9 0.00067 19.9 0.0 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC93568.1 - 8.6e-12 44.2 1.6 0.4 10.9 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMC93568.1 - 3.7e-11 41.9 7.7 0.0093 15.6 0.1 5.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 EMC93568.1 - 9.5e-07 28.8 4.9 0.0089 16.1 0.0 4.6 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC93568.1 - 5.4e-06 26.5 4.1 6 7.5 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC93568.1 - 6.6e-06 26.1 1.3 3.7e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EMC93568.1 - 2.5e-05 24.0 7.2 0.018 14.8 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 EMC93568.1 - 0.00025 20.7 0.0 1.6 8.6 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMC93568.1 - 0.001 18.2 1.3 0.99 8.4 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC93568.1 - 0.027 14.4 6.6 2.5 8.1 0.4 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EMC93568.1 - 0.035 14.0 0.5 0.69 9.8 0.1 3.2 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain RRM_1 PF00076.17 EMC93569.1 - 2.9e-33 113.3 0.7 5e-17 61.2 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC93569.1 - 2.7e-28 97.7 0.3 4.5e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC93569.1 - 4.8e-21 74.3 0.1 2.6e-12 46.3 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC93569.1 - 0.00021 20.9 0.1 0.23 11.2 0.0 2.7 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM PF05172.8 EMC93569.1 - 0.13 11.9 0.2 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Macoilin PF09726.4 EMC93569.1 - 0.41 8.8 5.9 0.36 9.0 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Rifin_STEVOR PF02009.11 EMC93569.1 - 1.6 8.2 4.6 2.9 7.4 3.2 1.4 1 0 0 1 1 1 0 Rifin/stevor family STT3 PF02516.9 EMC93570.1 - 1.2e-130 436.7 37.8 7.6e-127 424.2 24.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit MFS_1 PF07690.11 EMC93571.1 - 1e-35 123.0 29.6 1e-35 123.0 20.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 EMC93573.1 - 1.1e-25 90.4 1.7 1.2e-25 90.2 1.2 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr2 PF10383.4 EMC93573.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 1 0 1 1 1 0 Transcription-silencing protein Clr2 Sugar_tr PF00083.19 EMC93575.1 - 1e-19 70.5 6.9 1.2e-19 70.2 4.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC93575.1 - 3.8e-15 55.4 11.9 5.1e-15 55.0 8.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Tannase PF07519.6 EMC93577.1 - 1.6e-104 350.2 1.9 2.2e-103 346.5 1.3 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase SpoIIE PF07228.7 EMC93578.1 - 1.2e-10 41.3 2.3 4.7e-10 39.5 1.6 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EMC93578.1 - 7.8e-09 35.2 0.0 0.0026 17.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EMC93578.1 - 9.6e-05 21.8 1.9 0.00021 20.7 1.3 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Cupin_6 PF12852.2 EMC93578.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Cupin bZIP_1 PF00170.16 EMC93581.1 - 1.8e-08 34.1 10.5 1.8e-08 34.1 7.3 2.8 2 1 2 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.10 EMC93581.1 - 9.7e-07 28.5 8.3 9.7e-07 28.5 5.8 3.0 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC93581.1 - 3.6e-06 27.1 10.8 3.6e-06 27.1 7.5 3.3 3 1 1 4 4 4 1 bZIP Maf transcription factor DUF724 PF05266.9 EMC93581.1 - 0.26 10.8 15.3 0.59 9.7 10.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) phage_tail_N PF08400.5 EMC93581.1 - 0.27 10.9 0.8 4.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Prophage tail fibre N-terminal Endotoxin_N PF03945.9 EMC93581.1 - 0.62 9.4 4.2 0.93 8.8 2.1 1.8 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain Mnd1 PF03962.10 EMC93581.1 - 0.74 9.4 20.0 0.054 13.1 9.9 1.9 2 1 0 2 2 2 0 Mnd1 family APG6 PF04111.7 EMC93581.1 - 4.8 6.1 17.7 7.9 5.4 12.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Sel1 PF08238.7 EMC93582.1 - 1.5e-16 60.4 9.4 5.8e-06 26.7 0.1 3.8 3 0 0 3 3 3 3 Sel1 repeat zf-CCCH PF00642.19 EMC93583.1 - 1.1e-14 53.7 23.6 0.0001 21.8 2.4 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PDGF_N PF04692.8 EMC93583.1 - 2.6 8.6 6.5 0.71 10.4 1.9 2.0 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region WD40 PF00400.27 EMC93584.1 - 7.1e-40 133.4 17.9 6.5e-10 38.5 0.3 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EMC93584.1 - 5.3e-12 44.7 8.5 1e-11 43.8 5.9 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EMC93584.1 - 0.012 15.3 0.0 10 5.7 0.0 3.6 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A Ribosomal_S8e PF01201.17 EMC93587.1 - 5.4e-35 120.4 6.6 6e-34 117.0 4.6 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e DUF4407 PF14362.1 EMC93587.1 - 1.2 7.9 5.2 1.6 7.6 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3959 PF13105.1 EMC93587.1 - 4.6 6.5 9.2 1.5 8.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) BNR PF02012.15 EMC93590.1 - 8.2e-14 49.1 32.7 0.76 9.8 0.0 11.1 10 0 0 10 10 10 6 BNR/Asp-box repeat Pyr_redox PF00070.22 EMC93590.1 - 2.2e-13 50.4 0.7 6.4e-10 39.3 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC93590.1 - 1.3e-12 48.0 0.0 2.3e-11 43.9 0.0 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC93590.1 - 5.3e-07 29.9 0.3 0.00049 20.2 0.1 3.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC93590.1 - 0.0002 20.3 0.5 0.26 10.1 0.0 3.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EMC93590.1 - 0.0015 17.5 0.1 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 EMC93590.1 - 0.0068 16.3 1.5 0.9 9.5 0.0 3.1 3 0 0 3 3 3 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 EMC93590.1 - 0.053 12.5 0.1 0.12 11.4 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ThiF PF00899.16 EMC93590.1 - 0.16 11.8 0.1 9.1 6.1 0.0 2.6 2 0 0 2 2 2 0 ThiF family TatC PF00902.13 EMC93590.1 - 0.37 10.1 0.0 0.67 9.3 0.0 1.3 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF2667 PF10868.3 EMC93592.1 - 0.18 12.1 2.4 3.2 8.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2667) SUR7 PF06687.7 EMC93593.1 - 1.6e-10 40.8 10.8 2.7e-09 36.9 7.5 2.0 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EMC93593.1 - 0.0018 18.1 10.3 0.0018 18.1 7.1 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 PepSY_TM PF03929.11 EMC93593.1 - 0.042 14.2 0.9 0.042 14.2 0.6 3.4 4 0 0 4 4 4 0 PepSY-associated TM helix E1-E2_ATPase PF00122.15 EMC93593.1 - 0.43 9.5 4.8 0.78 8.7 3.3 1.3 1 0 0 1 1 1 0 E1-E2 ATPase DUF4282 PF14110.1 EMC93593.1 - 1.2 9.3 17.8 0.36 11.0 9.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) NPR3 PF03666.8 EMC93596.1 - 0.91 7.9 2.5 1.4 7.4 1.8 1.4 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF566 PF04484.7 EMC93596.1 - 6.8 6.0 8.7 7.9 5.8 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pkinase PF00069.20 EMC93597.1 - 7.8e-58 195.6 0.0 5.6e-37 127.3 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93597.1 - 6.4e-27 94.2 0.0 4.4e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EMC93597.1 - 3.3e-12 46.4 0.0 6.9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EMC93597.1 - 4.2e-09 35.7 0.4 8.3e-07 28.2 0.0 3.1 4 0 0 4 4 4 1 Kinase-like APH PF01636.18 EMC93597.1 - 2e-06 27.6 0.0 0.0026 17.5 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS PF00989.19 EMC93597.1 - 2.2e-05 24.2 0.0 6.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EMC93597.1 - 0.00092 19.2 0.0 0.0029 17.6 0.0 1.9 1 0 0 1 1 1 1 PAS fold Seadorna_VP7 PF07387.6 EMC93597.1 - 0.014 14.2 0.1 0.087 11.6 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Kdo PF06293.9 EMC93597.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 EMC93597.1 - 0.026 14.8 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 PAS domain Pox_ser-thr_kin PF05445.6 EMC93597.1 - 2.3 6.9 0.1 3.8 6.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNA_pol_Rpb4 PF03874.11 EMC93598.1 - 8.3e-20 70.9 0.0 1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 RhoGAP PF00620.22 EMC93599.1 - 2.5e-37 127.8 0.0 6.6e-37 126.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EMC93599.1 - 8.4e-28 96.2 40.8 1.5e-12 47.4 3.5 5.0 5 0 0 5 5 5 4 LIM domain DUF3620 PF12281.3 EMC93599.1 - 0.016 14.9 0.1 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3620) COesterase PF00135.23 EMC93600.1 - 4.5e-79 266.5 0.1 6.3e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC93600.1 - 7.7e-11 41.9 0.1 2.4e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC93600.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family GPI-anchored PF10342.4 EMC93601.1 - 4.1e-12 46.3 0.3 4.1e-12 46.3 0.2 3.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 EMC93602.1 - 7e-08 32.8 0.6 1.3e-07 31.9 0.2 1.5 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Prenyltransf PF01255.14 EMC93603.1 - 7.8e-08 31.7 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RRM_1 PF00076.17 EMC93607.1 - 3e-43 145.3 0.2 2e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC93607.1 - 4.2e-31 106.7 0.0 9.8e-15 54.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC93607.1 - 1.8e-18 66.1 0.0 1.5e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg6_Alg8 PF03155.10 EMC93611.1 - 3.8e-123 411.7 23.0 1.9e-78 264.4 6.4 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.8 EMC93612.1 - 2.6e-20 72.1 5.1 3.2e-20 71.8 3.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 EMC93612.1 - 0.0082 16.0 0.8 0.015 15.2 0.5 1.5 1 1 0 1 1 1 1 CHCH domain LRR_6 PF13516.1 EMC93613.1 - 2.5e-14 51.6 2.4 0.1 12.6 0.0 7.9 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EMC93613.1 - 3.5e-10 39.2 4.6 0.029 14.0 0.0 5.2 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) Cnd2 PF05786.9 EMC93613.1 - 4.7e-06 25.4 6.3 5.9e-06 25.1 4.4 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 LRR_1 PF00560.28 EMC93613.1 - 5.4e-05 22.6 5.0 6.8 7.1 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 EMC93613.1 - 0.016 14.9 8.3 9.6 6.0 0.0 4.5 3 2 1 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 EMC93613.1 - 0.16 12.2 5.2 64 4.4 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat Nop14 PF04147.7 EMC93613.1 - 5 4.9 24.5 7.3 4.3 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family SnoaL_4 PF13577.1 EMC93616.1 - 1e-25 90.0 0.1 1.2e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 EMC93616.1 - 1.7e-05 25.2 0.0 2.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Putative lumazine-binding SnoaL_2 PF12680.2 EMC93616.1 - 0.0003 21.1 0.4 0.00046 20.5 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EMC93616.1 - 0.00031 20.9 0.1 0.00037 20.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) LEH PF07858.7 EMC93616.1 - 0.084 12.8 0.1 0.92 9.5 0.1 2.0 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain DUF348 PF03990.9 EMC93616.1 - 1.4 8.5 3.3 48 3.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF348) SKG6 PF08693.5 EMC93618.1 - 3.7e-06 26.1 0.1 3.7e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EMC93618.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EMC93618.1 - 0.044 13.4 13.2 17 5.1 9.1 2.5 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 EMC93618.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2981 PF11200.3 EMC93618.1 - 1.5 7.7 4.3 3.5 6.5 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Rifin_STEVOR PF02009.11 EMC93618.1 - 2.3 7.7 4.6 9.2 5.8 3.2 1.8 1 1 0 1 1 1 0 Rifin/stevor family Peptidase_M1 PF01433.15 EMC93619.1 - 3.6e-74 250.1 0.0 4.6e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EMC93619.1 - 2.6e-41 140.5 0.0 4.2e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EMC93619.1 - 2.6e-17 63.0 0.1 6.5e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EMC93619.1 - 0.16 11.9 2.7 1.2 9.1 1.9 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase ORC4_C PF14629.1 EMC93620.1 - 1.5e-36 125.6 0.0 2.7e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EMC93620.1 - 3.9e-15 56.3 2.0 2.8e-14 53.5 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC93620.1 - 2e-09 37.6 0.3 1.1e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMC93620.1 - 5.4e-06 26.1 0.0 3.3e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 EMC93620.1 - 9.7e-05 22.5 0.0 0.00035 20.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMC93620.1 - 0.00012 21.6 1.4 0.0095 15.4 0.0 3.1 2 1 0 3 3 3 1 AAA-like domain KAP_NTPase PF07693.9 EMC93620.1 - 0.00014 20.9 0.0 0.00035 19.6 0.0 1.6 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 EMC93620.1 - 0.00022 21.0 0.0 0.00072 19.3 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 EMC93620.1 - 0.00057 18.8 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EMC93620.1 - 0.00062 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EMC93620.1 - 0.0016 18.3 0.0 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMC93620.1 - 0.0035 17.8 0.0 0.0096 16.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 EMC93620.1 - 0.0051 16.6 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC93620.1 - 0.0095 16.7 0.0 0.028 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMC93620.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EMC93620.1 - 0.019 14.4 0.1 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3912 PF13051.1 EMC93620.1 - 0.052 13.2 0.6 0.13 12.0 0.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3912) Dynamin_N PF00350.18 EMC93620.1 - 0.062 13.1 0.4 0.67 9.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family LacAB_rpiB PF02502.13 EMC93620.1 - 0.071 12.7 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Ribose/Galactose Isomerase FAD_binding_3 PF01494.14 EMC93621.1 - 2.3e-28 99.3 0.1 3e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC93621.1 - 3.3e-10 39.4 0.5 8.6e-08 31.4 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC93621.1 - 7.5e-07 29.4 6.3 1.9e-05 24.9 0.1 3.3 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC93621.1 - 9.5e-07 28.7 0.0 1.3e-05 25.0 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMC93621.1 - 6.4e-05 21.7 1.9 0.062 11.9 0.3 2.9 1 1 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.17 EMC93621.1 - 0.00012 21.0 0.5 0.0012 17.8 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EMC93621.1 - 0.00014 21.0 0.2 0.00023 20.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 EMC93621.1 - 0.00017 21.3 0.2 0.00042 20.0 0.1 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EMC93621.1 - 0.0002 20.3 1.0 0.00034 19.5 0.2 1.6 1 1 1 2 2 2 1 FAD binding domain ApbA PF02558.11 EMC93621.1 - 0.00056 19.3 0.2 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EMC93621.1 - 0.00094 17.7 0.2 0.0088 14.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMC93621.1 - 0.0026 17.6 0.9 0.0061 16.4 0.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC93621.1 - 0.0039 16.1 0.2 0.012 14.6 0.1 1.9 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMC93621.1 - 0.0045 17.0 0.6 0.33 10.9 0.0 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMC93621.1 - 0.02 14.9 2.1 0.036 14.1 0.0 2.4 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EMC93621.1 - 0.021 15.3 0.0 0.07 13.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain XdhC_C PF13478.1 EMC93621.1 - 0.043 14.1 0.1 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 EMC93621.1 - 0.05 12.9 1.7 0.075 12.4 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 EMC93621.1 - 0.051 13.5 0.2 0.12 12.3 0.0 1.7 2 0 0 2 2 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 EMC93621.1 - 0.1 12.8 0.2 0.23 11.7 0.1 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 EMC93621.1 - 0.12 11.4 0.6 2.2 7.2 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase bHLH-MYC_N PF14215.1 EMC93624.1 - 0.024 14.8 0.1 0.078 13.1 0.1 1.9 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Neurensin PF14927.1 EMC93624.1 - 0.55 9.6 2.9 0.93 8.8 0.7 2.2 2 0 0 2 2 2 0 Neurensin DUF2418 PF10332.4 EMC93626.1 - 1.1e-26 93.0 0.0 2.1e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF2397 PF09660.5 EMC93627.1 - 0.0016 17.0 0.1 0.0019 16.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) Gsf2 PF11055.3 EMC93627.1 - 0.0061 15.1 0.0 0.0072 14.8 0.0 1.1 1 0 0 1 1 1 1 Glucose signalling factor 2 Yip1 PF04893.12 EMC93629.1 - 1.3e-13 50.7 12.1 1.7e-13 50.4 8.4 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EMC93629.1 - 0.0063 16.1 7.2 0.0098 15.5 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Pkinase PF00069.20 EMC93631.1 - 3.3e-10 39.5 0.0 6.6e-09 35.2 0.0 2.6 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93631.1 - 6.2e-09 35.3 0.0 5.4e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC93631.1 - 0.87 9.2 6.7 9.7 5.8 0.3 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family PHD PF00628.24 EMC93632.1 - 2e-08 33.7 5.3 4.2e-08 32.7 3.6 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EMC93632.1 - 4.7e-06 27.0 1.6 4.8e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 SET domain COesterase PF00135.23 EMC93634.1 - 7.5e-88 295.5 0.3 1.1e-87 294.9 0.2 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC93634.1 - 1.3e-09 37.9 0.6 8e-09 35.3 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC93634.1 - 0.00048 19.3 0.1 0.00081 18.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC93634.1 - 0.016 14.9 1.6 0.017 14.9 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Collagen PF01391.13 EMC93634.1 - 0.37 10.3 8.1 0.22 11.0 2.9 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) zf-C2H2 PF00096.21 EMC93637.1 - 0.076 13.3 0.3 0.076 13.3 0.2 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 EMC93637.1 - 0.2 11.7 3.1 0.54 10.4 2.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TIM21 PF08294.6 EMC93639.1 - 9.3e-41 138.8 0.0 1.1e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EMC93639.1 - 2.3e-05 23.8 0.0 0.00029 20.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Cas_VVA1548 PF09652.5 EMC93639.1 - 0.0031 17.4 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative CRISPR-associated protein (Cas_VVA1548) HET PF06985.6 EMC93640.1 - 8e-35 120.0 1.2 1.3e-34 119.3 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PMC2NT PF08066.7 EMC93641.1 - 0.00054 20.1 1.1 0.0019 18.4 0.8 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain ApoLp-III PF07464.6 EMC93641.1 - 0.0009 19.2 1.1 0.0009 19.2 0.7 2.2 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF722 PF05263.6 EMC93641.1 - 0.22 11.6 2.6 7.1 6.7 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF722) adh_short PF00106.20 EMC93642.1 - 9.8e-30 103.6 1.1 1.5e-29 103.0 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC93642.1 - 1.6e-22 80.5 0.1 2e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC93642.1 - 2.1e-14 53.5 1.1 3.8e-14 52.7 0.8 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMC93642.1 - 9.5e-05 22.1 0.1 0.00024 20.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMC93642.1 - 0.0017 17.8 0.3 0.0025 17.2 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC93642.1 - 0.0039 16.1 0.2 0.0059 15.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMC93642.1 - 0.049 13.7 0.1 0.08 13.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TAP42 PF04177.7 EMC93642.1 - 0.14 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family Rad4 PF03835.10 EMC93643.1 - 5.6e-33 113.3 3.2 1.6e-32 111.9 0.1 2.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EMC93643.1 - 4.3e-28 96.8 0.4 1.1e-27 95.4 0.0 2.0 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EMC93643.1 - 2.1e-17 63.1 0.1 2.1e-17 63.1 0.1 3.3 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EMC93643.1 - 1.1e-15 56.8 0.1 2.4e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 EMC93643.1 - 0.00011 22.3 0.1 0.00079 19.6 0.0 2.5 2 1 0 2 2 2 1 Transglutaminase-like superfamily TPP_enzyme_N PF02776.13 EMC93644.1 - 9.5e-25 87.0 0.4 1.5e-24 86.4 0.3 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMC93644.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain GalP_UDP_transf PF01087.17 EMC93646.1 - 2.4e-66 223.2 0.5 1.3e-64 217.6 0.2 2.4 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EMC93646.1 - 1.1e-54 184.4 0.0 2.5e-54 183.3 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Filament PF00038.16 EMC93646.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein F-box-like PF12937.2 EMC93650.1 - 0.013 15.2 0.4 0.24 11.1 0.0 2.8 3 0 0 3 3 3 0 F-box-like Methyltransf_23 PF13489.1 EMC93651.1 - 1.5e-14 54.0 0.0 1.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC93651.1 - 8.1e-13 48.6 0.0 1.4e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC93651.1 - 4.2e-12 46.4 0.5 1.6e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC93651.1 - 2.8e-11 43.2 0.0 4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC93651.1 - 2.1e-10 41.1 0.0 3.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC93651.1 - 9.6e-10 38.7 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC93651.1 - 1.2e-08 34.9 0.1 2.4e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 EMC93651.1 - 5.5e-07 28.8 0.0 6.7e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 EMC93651.1 - 5.6e-06 25.6 0.0 7.4e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMC93651.1 - 2.9e-05 23.3 0.0 3.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EMC93651.1 - 4.5e-05 22.8 0.0 6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 EMC93651.1 - 0.002 17.4 0.0 1.2 8.3 0.0 2.1 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain RrnaAD PF00398.15 EMC93651.1 - 0.032 13.2 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 EMC93651.1 - 0.085 11.5 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Glyco_transf_34 PF05637.7 EMC93652.1 - 3.7e-63 213.2 0.0 1.2e-62 211.5 0.0 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family F-box-like PF12937.2 EMC93653.1 - 0.0033 17.1 0.1 0.0063 16.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like DRMBL PF07522.9 EMC93654.1 - 8.7e-33 112.6 0.0 1.8e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EMC93654.1 - 9.7e-12 44.8 0.0 2.2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC93654.1 - 0.018 14.7 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pirin PF02678.11 EMC93656.1 - 2.2e-31 107.8 0.3 4.4e-31 106.9 0.1 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EMC93656.1 - 2.2e-20 72.6 0.0 4.7e-19 68.3 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EMC93656.1 - 8.8e-06 25.1 0.4 0.00013 21.3 0.3 2.3 2 0 0 2 2 2 1 Cupin domain Abhydrolase_6 PF12697.2 EMC93657.1 - 1.2e-29 103.7 0.0 2.3e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93657.1 - 5.4e-14 52.3 0.0 6.4e-12 45.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93657.1 - 6.3e-08 32.4 0.0 2e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMC93657.1 - 1.8e-05 24.3 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase EthD PF07110.6 EMC93657.1 - 6.3e-05 23.8 0.1 0.17 12.8 0.0 2.7 2 0 0 2 2 2 2 EthD domain Ndr PF03096.9 EMC93657.1 - 0.0013 17.2 0.0 0.0019 16.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Methyltransf_23 PF13489.1 EMC93659.1 - 2e-24 86.1 0.1 3.2e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC93659.1 - 6.6e-12 45.2 0.0 2.4e-10 40.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC93659.1 - 2.9e-10 40.4 0.0 6.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC93659.1 - 1.5e-09 38.4 0.0 1.4e-08 35.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC93659.1 - 2.9e-07 30.8 0.0 1.5e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC93659.1 - 1.4e-05 24.3 0.0 0.00012 21.3 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMC93659.1 - 0.00041 19.5 0.0 0.00057 19.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EMC93659.1 - 0.00056 19.0 0.0 0.0019 17.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EMC93659.1 - 0.0014 18.6 0.0 0.01 15.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EMC93659.1 - 0.0033 16.7 0.0 0.007 15.6 0.0 1.5 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 EMC93659.1 - 0.0038 16.6 0.0 0.067 12.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EMC93659.1 - 0.014 15.3 0.0 0.049 13.6 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EMC93659.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 EMC93659.1 - 0.035 14.4 0.0 0.1 13.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EMC93659.1 - 0.054 12.5 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Sec39 PF08314.6 EMC93659.1 - 0.076 10.9 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 GST_N PF02798.15 EMC93660.1 - 0.03 14.5 0.1 0.42 10.8 0.0 2.7 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain zf-ribbon_3 PF13248.1 EMC93663.1 - 0.056 12.6 6.0 0.1 11.8 0.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 EMC93663.1 - 0.057 13.1 7.4 0.077 12.7 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DnaJ_CXXCXGXG PF00684.14 EMC93663.1 - 0.08 13.0 0.2 0.099 12.7 0.1 1.1 1 0 0 1 1 1 0 DnaJ central domain YhfH PF14149.1 EMC93663.1 - 0.15 11.8 0.5 0.15 11.8 0.3 1.9 2 0 0 2 2 2 0 YhfH-like protein DZR PF12773.2 EMC93663.1 - 0.27 11.0 2.1 0.65 9.8 1.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EMC93663.1 - 0.29 10.6 4.0 1.1 8.8 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 EMC93663.1 - 0.36 10.3 4.1 2.4 7.7 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DNA_ligase_ZBD PF03119.11 EMC93663.1 - 1.4 8.6 4.5 0.72 9.5 0.4 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-FPG_IleRS PF06827.9 EMC93663.1 - 2.8 7.6 7.6 2.7 7.7 0.3 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-tcix PF14952.1 EMC93663.1 - 3.5 7.0 8.6 0.49 9.7 1.0 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Zn-ribbon_8 PF09723.5 EMC93663.1 - 4.2 7.4 5.8 63 3.6 4.0 2.3 1 1 0 1 1 1 0 Zinc ribbon domain bZIP_1 PF00170.16 EMC93664.1 - 0.00031 20.6 9.0 0.00062 19.6 6.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC93664.1 - 0.43 10.4 9.6 0.43 10.4 5.8 1.8 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 EMC93664.1 - 0.77 10.0 8.7 1.3 9.3 6.0 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Fungal_trans PF04082.13 EMC93665.1 - 1.8e-15 56.5 0.1 3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93665.1 - 3.7e-06 26.7 10.6 6.6e-06 25.9 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EMC93665.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 FAD_binding_3 PF01494.14 EMC93667.1 - 2.1e-17 63.2 0.5 1.9e-16 60.0 0.2 2.5 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EMC93667.1 - 8e-09 34.8 0.6 4e-05 22.6 0.2 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC93667.1 - 2.9e-07 30.4 0.3 6.9e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC93667.1 - 4.6e-07 30.1 0.3 6.1e-05 23.3 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC93667.1 - 2.7e-06 26.4 0.2 6.6e-06 25.2 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMC93667.1 - 1.8e-05 23.3 0.1 0.014 13.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMC93667.1 - 3e-05 23.9 0.4 0.00015 21.7 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC93667.1 - 0.00027 19.9 0.0 0.00045 19.1 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMC93667.1 - 0.00089 18.2 0.1 0.21 10.4 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 EMC93667.1 - 0.0037 16.3 1.6 0.011 14.7 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC93667.1 - 0.021 14.9 0.1 0.095 12.7 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC93667.1 - 0.039 13.0 0.0 0.089 11.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EMC93667.1 - 0.048 13.4 0.6 9.4 5.9 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EMC93667.1 - 0.054 13.0 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EMC93667.1 - 0.12 11.8 0.4 0.3 10.5 0.3 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMC93667.1 - 0.14 11.8 0.2 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EMC93667.1 - 0.62 9.8 2.1 0.85 9.4 0.3 2.0 2 0 0 2 2 2 0 ThiF family Glyco_hydro_43 PF04616.9 EMC93669.1 - 1.5e-28 99.7 4.1 3.1e-27 95.4 2.8 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 EMC93670.1 - 1.9e-42 145.2 42.9 1.2e-41 142.6 29.2 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4307 PF14155.1 EMC93670.1 - 1.5 8.6 5.0 0.97 9.2 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF3735 PF12537.3 EMC93670.1 - 4.8 7.2 8.5 4.1 7.5 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3735) Cu-oxidase_3 PF07732.10 EMC93672.1 - 8.8e-49 164.1 6.7 4.4e-45 152.2 0.7 4.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC93672.1 - 7.1e-48 161.6 8.9 8.7e-42 141.8 0.2 4.8 4 1 0 4 4 4 4 Multicopper oxidase CBM_20 PF00686.14 EMC93672.1 - 4.2e-35 119.2 0.5 2.6e-29 100.6 0.1 3.0 1 1 1 2 2 2 2 Starch binding domain Cu-oxidase PF00394.17 EMC93672.1 - 5.4e-35 120.6 0.1 2e-34 118.8 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase CBM_25 PF03423.8 EMC93672.1 - 0.0045 17.0 0.2 0.022 14.8 0.2 2.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) Na_Ca_ex PF01699.19 EMC93673.1 - 2.3e-27 95.2 20.9 9.8e-15 54.3 3.6 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 EMC93673.1 - 0.12 11.7 7.7 4.2 6.7 3.7 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Wzy_C PF04932.10 EMC93673.1 - 0.46 10.2 5.6 0.28 10.9 0.1 3.0 2 1 0 2 2 2 0 O-Antigen ligase TspO_MBR PF03073.10 EMC93674.1 - 1.2e-43 148.1 5.0 1.5e-43 147.8 3.5 1.1 1 0 0 1 1 1 1 TspO/MBR family Corona_NS3b PF03053.9 EMC93674.1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 ORF3b coronavirus protein DUF4187 PF13821.1 EMC93675.1 - 6e-22 76.9 0.1 1.4e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EMC93675.1 - 4.1e-21 75.0 1.0 2e-20 72.8 0.7 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EMC93675.1 - 3.3e-12 47.0 0.1 9.6e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Beta-lactamase PF00144.19 EMC93676.1 - 6.3e-29 101.0 0.1 1.1e-28 100.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase ABC_tran PF00005.22 EMC93677.1 - 1.9e-27 96.2 0.0 1.2e-26 93.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EMC93677.1 - 6.5e-05 23.0 0.0 0.0036 17.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_4 PF12730.2 EMC93677.1 - 9.3e-05 21.6 16.0 9.3e-05 21.6 11.1 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EMC93677.1 - 0.0053 15.9 0.2 0.0092 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMC93677.1 - 0.014 14.8 0.1 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMC93677.1 - 0.017 15.0 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EMC93677.1 - 0.047 13.1 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 EMC93677.1 - 0.054 12.2 0.5 0.11 11.2 0.3 1.4 1 0 0 1 1 1 0 ArgK protein MMR_HSR1 PF01926.18 EMC93677.1 - 0.068 13.1 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FAD_binding_2 PF00890.19 EMC93678.1 - 2.9e-125 418.4 2.4 3.8e-125 418.0 1.7 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMC93678.1 - 1.9e-46 157.0 2.8 2.8e-46 156.5 2.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EMC93678.1 - 4.5e-07 29.9 0.0 0.039 13.8 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC93678.1 - 8e-06 25.1 0.1 0.0042 16.2 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EMC93678.1 - 5.5e-05 22.1 1.5 0.069 11.9 1.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EMC93678.1 - 9.6e-05 21.4 0.1 0.0047 15.8 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMC93678.1 - 0.01 14.9 0.1 0.022 13.8 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EMC93678.1 - 0.095 11.1 0.3 0.37 9.2 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein Methyltransf_2 PF00891.13 EMC93682.1 - 8.6e-28 97.1 0.1 2.9e-27 95.4 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase BTAD PF03704.12 EMC93682.1 - 0.091 13.0 2.4 0.21 11.9 1.6 1.6 1 0 0 1 1 1 0 Bacterial transcriptional activator domain HTH_28 PF13518.1 EMC93682.1 - 0.15 12.1 0.1 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.11 EMC93683.1 - 9e-23 80.5 22.0 9e-23 80.5 15.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC93683.1 - 7.9e-06 24.3 3.7 1.2e-05 23.7 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3593 PF12159.3 EMC93684.1 - 2.4 8.0 7.1 2.2 8.1 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) zf-RING_2 PF13639.1 EMC93686.1 - 2.8e-13 49.4 12.2 3.8e-13 49.0 8.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC93686.1 - 3.2e-08 33.5 9.2 5.1e-08 32.9 6.4 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC93686.1 - 1.2e-06 28.4 12.2 1.8e-06 27.8 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC93686.1 - 1.9e-06 27.4 11.5 2.6e-06 26.9 8.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC93686.1 - 5.7e-05 22.8 5.7 9.6e-05 22.1 3.9 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EMC93686.1 - 0.00012 21.7 8.6 0.00017 21.1 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC93686.1 - 0.00012 21.7 10.6 0.00016 21.2 7.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EMC93686.1 - 0.016 14.7 4.3 0.025 14.0 3.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EMC93686.1 - 0.044 13.8 12.8 0.069 13.2 8.9 1.3 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EMC93686.1 - 0.14 11.7 10.0 11 5.7 6.9 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMC93686.1 - 0.16 11.6 6.3 0.32 10.7 4.0 1.8 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.6 EMC93686.1 - 0.51 10.3 10.8 1.3 9.0 7.5 1.7 1 1 0 1 1 1 0 RING-like domain Thionin PF00321.12 EMC93686.1 - 0.71 10.1 4.8 0.29 11.3 1.1 1.9 1 1 1 2 2 2 0 Plant thionin FANCL_C PF11793.3 EMC93686.1 - 0.79 9.7 10.4 2.9 7.9 7.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EMC93686.1 - 10 6.1 9.0 0.24 11.2 1.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RNA_pol_I_TF PF04090.7 EMC93688.1 - 2.7e-15 56.1 0.0 6.7e-14 51.6 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.1 EMC93688.1 - 0.47 11.0 6.4 2 9.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC93688.1 - 6.2 7.0 8.1 1.2e+02 2.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DPBB_1 PF03330.13 EMC93689.1 - 3.1e-08 33.4 0.3 8.1e-08 32.1 0.2 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel CDC73 PF05179.9 EMC93692.1 - 9.1e-43 146.5 0.0 1.3e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family E1-E2_ATPase PF00122.15 EMC93693.1 - 1.4e-67 227.1 0.1 1.4e-67 227.1 0.1 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EMC93693.1 - 2e-23 83.9 0.0 1.3e-22 81.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMC93693.1 - 4.7e-12 45.1 0.1 1.4e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC93693.1 - 5.5e-12 46.2 0.0 1.3e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC93693.1 - 0.00059 19.4 0.2 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC93693.1 - 0.0057 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 EMC93693.1 - 0.094 12.5 0.2 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif p450 PF00067.17 EMC93694.1 - 3.2e-72 243.5 0.0 4e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 EMC93695.1 - 9.6e-52 175.9 45.4 1.4e-51 175.3 31.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC93695.1 - 1.3e-30 106.1 33.4 1.3e-30 106.1 23.1 2.0 2 0 0 2 2 2 1 Amino acid permease DUF1774 PF08611.5 EMC93695.1 - 0.46 10.6 0.1 0.46 10.6 0.0 3.6 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) SHR3_chaperone PF08229.6 EMC93695.1 - 2.2 7.1 6.1 0.2 10.5 0.7 1.8 2 0 0 2 2 2 0 ER membrane protein SH3 Amidohydro_4 PF13147.1 EMC93696.1 - 5.5e-22 79.1 0.7 1.3e-14 54.9 0.0 3.1 1 1 1 3 3 3 3 Amidohydrolase Amidohydro_1 PF01979.15 EMC93696.1 - 6e-15 55.7 0.4 3.2e-13 50.0 0.3 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMC93696.1 - 3.4e-11 42.7 0.1 8.5e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC93696.1 - 1e-10 41.4 1.0 7.8e-07 28.6 0.0 2.6 1 1 0 1 1 1 1 Amidohydrolase family Glyco_transf_4 PF13439.1 EMC93696.1 - 0.069 12.8 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Amidohydro_2 PF04909.9 EMC93697.1 - 2.8e-30 105.8 0.3 8.7e-30 104.1 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase Fe-ADH PF00465.14 EMC93698.1 - 1.2e-66 224.8 0.0 1.4e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMC93698.1 - 1.8e-13 50.3 0.0 3.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase MARVEL PF01284.18 EMC93699.1 - 0.3 10.9 9.9 0.51 10.1 6.9 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF962 PF06127.6 EMC93699.1 - 1.1 9.1 6.5 0.8 9.6 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF962) EB PF01683.13 EMC93700.1 - 5.4 7.1 6.7 0.77 9.8 1.2 2.0 2 0 0 2 2 2 0 EB module PAN_1 PF00024.21 EMC93701.1 - 0.014 15.1 0.2 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 PAN domain Apc3 PF12895.2 EMC93702.1 - 0.05 13.7 0.1 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Brix PF04427.13 EMC93704.1 - 1.5e-32 112.8 0.0 2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Glutaredoxin PF00462.19 EMC93705.1 - 1.7e-20 72.7 0.0 3.7e-19 68.4 0.0 2.6 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EMC93705.1 - 4.8e-15 55.1 0.0 9.3e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMC93705.1 - 0.0018 18.3 0.0 0.12 12.5 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC93705.1 - 0.16 12.1 0.2 1.7 8.8 0.0 2.4 2 2 1 3 3 3 0 Thioredoxin-like domain MAPEG PF01124.13 EMC93706.1 - 1.1e-14 54.1 0.8 1.5e-14 53.7 0.5 1.1 1 0 0 1 1 1 1 MAPEG family CoA_binding_2 PF13380.1 EMC93707.1 - 3.8e-24 85.0 0.0 4.7e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain HIT PF01230.18 EMC93708.1 - 6.2e-23 81.1 0.3 8.2e-23 80.7 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMC93708.1 - 2.8e-06 27.5 0.3 3.9e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EMC93708.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 EF-hand_7 PF13499.1 EMC93710.1 - 1.9e-12 47.1 0.2 7.6e-08 32.3 0.2 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC93710.1 - 2.4e-09 36.2 1.6 4.5e-05 22.9 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.1 EMC93710.1 - 1.5e-07 31.1 0.0 0.0025 17.6 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMC93710.1 - 2.7e-07 29.3 2.9 0.0016 17.5 0.0 3.5 4 1 1 5 5 5 2 EF hand EF-hand_8 PF13833.1 EMC93710.1 - 1e-05 25.0 0.7 0.00036 20.0 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair UPF0154 PF03672.8 EMC93710.1 - 0.03 13.9 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) zf-AN1 PF01428.11 EMC93711.1 - 1.3e-22 79.4 20.9 1.3e-11 44.1 5.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EMC93711.1 - 0.051 13.4 16.9 0.033 14.0 2.7 2.4 2 0 0 2 2 2 0 IBR domain CpXC PF14353.1 EMC93711.1 - 0.11 12.4 0.2 0.11 12.4 0.1 2.4 2 1 1 3 3 3 0 CpXC protein Transp_Tc5_C PF04236.10 EMC93711.1 - 0.35 11.1 13.3 0.37 11.0 1.4 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain AFG1_ATPase PF03969.11 EMC93714.1 - 2.5e-92 309.5 0.5 1.8e-86 290.1 0.0 2.4 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EMC93714.1 - 0.0001 22.3 0.1 0.36 10.8 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EMC93714.1 - 0.00059 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EMC93714.1 - 0.001 18.7 0.1 0.38 10.3 0.2 2.5 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.1 EMC93714.1 - 0.0043 17.1 0.0 0.013 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMC93714.1 - 0.0091 16.1 0.2 0.034 14.3 0.0 2.1 2 1 0 2 2 2 1 RNA helicase NACHT PF05729.7 EMC93714.1 - 0.048 13.3 0.1 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EMC93714.1 - 0.077 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EMC93714.1 - 0.096 12.8 0.1 0.45 10.7 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EMC93714.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NMT1 PF09084.6 EMC93716.1 - 4.9e-75 251.8 0.0 6.4e-75 251.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EMC93716.1 - 8.9e-07 28.5 0.3 0.031 13.6 0.0 3.5 2 1 2 4 4 4 3 NMT1-like family NAD_binding_2 PF03446.10 EMC93717.1 - 1.9e-34 118.8 0.2 2.5e-34 118.4 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMC93717.1 - 4.2e-27 94.6 0.0 7.3e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMC93717.1 - 4.3e-06 27.0 0.0 8.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMC93717.1 - 2.3e-05 23.6 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMC93717.1 - 0.0076 15.9 0.0 0.02 14.5 0.0 1.7 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 EMC93717.1 - 0.0088 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EMC93717.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.4 EMC93717.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain DUF3237 PF11578.3 EMC93718.1 - 1.3e-31 108.9 0.0 1.5e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) SYF2 PF08231.7 EMC93719.1 - 2.5e-43 147.8 6.9 2.5e-43 147.8 4.8 2.1 2 0 0 2 2 2 1 SYF2 splicing factor DUF1176 PF06674.6 EMC93719.1 - 0.47 9.5 10.3 0.86 8.6 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1176) SMC_N PF02463.14 EMC93720.1 - 8.1e-62 208.3 14.0 6.8e-61 205.3 9.7 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMC93720.1 - 3.3e-28 98.0 0.2 1.9e-27 95.6 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMC93720.1 - 1.2e-14 55.0 0.1 4.4e-06 26.8 0.3 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMC93720.1 - 4.6e-05 22.8 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EMC93720.1 - 0.00012 22.5 56.3 0.00012 22.5 39.0 7.3 2 1 0 3 3 2 2 AAA domain Spc7 PF08317.6 EMC93720.1 - 0.00052 18.7 102.6 0.0029 16.3 12.2 6.2 2 2 4 6 6 6 3 Spc7 kinetochore protein APG6 PF04111.7 EMC93720.1 - 0.0022 17.0 11.5 0.0022 17.0 7.9 7.5 2 2 6 8 8 8 4 Autophagy protein Apg6 BLOC1_2 PF10046.4 EMC93720.1 - 0.0068 16.5 0.6 0.0068 16.5 0.4 9.7 7 4 4 11 11 11 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EMC93720.1 - 0.21 10.0 0.0 0.16 10.4 14.5 5.6 3 2 3 6 6 6 0 AAA domain Reo_sigmaC PF04582.7 EMC93720.1 - 0.68 9.0 30.3 0.56 9.3 3.4 4.7 4 1 1 5 5 5 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EMC93720.1 - 7.2 3.7 118.3 0.039 11.3 9.4 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF3584) YL1 PF05764.8 EMC93721.1 - 0.37 10.3 19.6 2.5 7.6 0.1 4.0 3 0 0 3 3 3 0 YL1 nuclear protein Abhydrolase_6 PF12697.2 EMC93722.1 - 1.1e-24 87.5 2.6 1.1e-23 84.3 1.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93722.1 - 7.1e-11 42.0 3.4 3.6e-10 39.8 2.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93722.1 - 1.2e-08 34.8 0.0 3.2e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC93722.1 - 4.5e-08 32.8 0.1 1.5e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase AXE1 PF05448.7 EMC93722.1 - 0.015 13.8 0.0 0.023 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EMC93722.1 - 0.016 14.5 0.1 0.033 13.6 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Beach PF02138.13 EMC93723.1 - 1.2e-107 359.3 0.0 2e-107 358.6 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EMC93723.1 - 3e-10 39.8 0.0 7.5e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EMC93723.1 - 2e-09 37.9 0.0 6.2e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 EMC93723.1 - 6.9e-07 28.9 0.7 6.7e-05 22.6 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat RYDR_ITPR PF01365.16 EMC93723.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 RIH domain DUF148 PF02520.12 EMC93723.1 - 0.31 10.8 1.2 0.77 9.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Peptidase_S8 PF00082.17 EMC93724.1 - 1.3e-52 178.7 8.9 1.8e-52 178.2 6.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMC93724.1 - 3.6e-21 75.5 0.5 9.4e-21 74.1 0.3 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Acyltransferase PF01553.16 EMC93725.1 - 9e-32 109.2 0.0 1.6e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Poly_export PF02563.11 EMC93725.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein adh_short PF00106.20 EMC93726.1 - 1.7e-28 99.6 0.9 7.7e-28 97.5 0.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC93726.1 - 1.3e-11 44.7 0.0 1.7e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC93726.1 - 1.5e-11 44.2 0.1 3.6e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC93726.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC93726.1 - 0.00017 21.6 1.3 0.092 12.7 0.6 2.4 1 1 1 2 2 2 2 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMC93726.1 - 0.033 13.9 0.3 0.06 13.1 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EMC93726.1 - 0.071 12.3 0.2 0.11 11.7 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family Ribonuclease PF00545.15 EMC93727.1 - 8.4e-19 67.4 2.6 1e-18 67.1 1.4 1.5 1 1 1 2 2 2 1 ribonuclease zf-C2HC PF01530.13 EMC93728.1 - 1.5 8.6 0.1 1.5 8.6 0.0 3.2 3 1 0 3 3 3 0 Zinc finger, C2HC type Transaldolase PF00923.14 EMC93729.1 - 1.3e-94 316.5 2.3 1.5e-94 316.3 1.6 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 EMC93729.1 - 0.033 13.4 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Sod_Cu PF00080.15 EMC93730.1 - 3.6e-44 150.3 6.9 4.2e-44 150.1 4.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) COXG PF06240.8 EMC93730.1 - 0.042 13.5 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) adh_short PF00106.20 EMC93731.1 - 5.7e-15 55.6 0.0 5.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMC93731.1 - 1.9e-06 27.8 0.0 0.0067 16.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC93731.1 - 0.022 14.4 0.0 0.9 9.1 0.0 2.1 2 0 0 2 2 2 0 KR domain Ras PF00071.17 EMC93732.1 - 1.6e-52 177.1 0.0 1.9e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC93732.1 - 1.4e-22 80.3 0.0 1.3e-21 77.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC93732.1 - 7.8e-07 28.4 0.0 8.8e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC93732.1 - 2.1e-06 27.2 0.1 5.3e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC93732.1 - 3.5e-06 26.9 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC93732.1 - 0.0025 17.0 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EMC93732.1 - 0.0032 17.6 0.1 0.084 13.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 EMC93732.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 KTI12 PF08433.5 EMC93732.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 1 0 2 2 2 0 Chromatin associated protein KTI12 DUF1620 PF07774.8 EMC93733.1 - 3.8e-68 228.9 0.0 6e-68 228.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EMC93733.1 - 4.3e-23 82.0 8.6 4.1e-21 75.5 1.2 2.8 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EMC93733.1 - 1.6e-08 33.6 0.1 0.069 12.7 0.0 4.5 5 0 0 5 5 5 3 PQQ enzyme repeat adh_short_C2 PF13561.1 EMC93734.1 - 5.5e-24 85.2 0.0 6.6e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC93734.1 - 3.5e-14 53.0 0.0 5e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93734.1 - 5.4e-06 26.2 0.0 7.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMC93734.1 - 0.0014 18.3 0.3 0.0039 16.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMC93734.1 - 0.0022 17.4 0.0 0.016 14.6 0.0 2.1 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EMC93734.1 - 0.0034 16.4 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EMC93734.1 - 0.0072 16.3 0.1 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Catalase-rel PF06628.7 EMC93734.1 - 0.019 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive 3HCDH_N PF02737.13 EMC93734.1 - 0.033 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMC93734.1 - 0.038 14.0 0.0 0.064 13.3 0.0 1.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Tir_receptor_C PF07489.6 EMC93734.1 - 0.046 13.4 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus AdoHcyase_NAD PF00670.16 EMC93734.1 - 0.051 13.4 0.2 0.098 12.4 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 EMC93734.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EMC93734.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding SNase PF00565.12 EMC93735.1 - 1.3e-78 260.1 0.0 2.6e-26 92.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EMC93735.1 - 3.9e-20 71.9 0.0 9.6e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EMC93735.1 - 4.3e-07 29.3 0.0 9.3e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) RIO1 PF01163.17 EMC93736.1 - 3e-71 238.6 0.1 3e-71 238.6 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EMC93736.1 - 2.4e-05 24.1 0.5 0.017 14.8 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family YL1 PF05764.8 EMC93736.1 - 0.00078 19.1 21.2 0.038 13.5 0.7 2.3 2 0 0 2 2 2 2 YL1 nuclear protein Kdo PF06293.9 EMC93736.1 - 0.0031 16.6 3.2 0.53 9.3 0.0 3.2 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleo_P87 PF07267.6 EMC93736.1 - 0.83 8.2 11.7 0.12 11.0 5.2 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Spt5_N PF11942.3 EMC93736.1 - 6.4 7.4 33.3 0.31 11.6 11.1 3.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal RRM_1 PF00076.17 EMC93739.1 - 2.2e-14 52.8 0.1 4.3e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC93739.1 - 1.1e-10 41.2 0.0 3.3e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EMC93740.1 - 1.3e-38 129.5 13.3 2.5e-10 39.8 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EMC93740.1 - 0.046 11.8 0.7 4.1 5.4 0.1 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 EMC93740.1 - 0.084 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature NUDE_C PF04880.8 EMC93741.1 - 1.2e-17 64.8 2.0 1.2e-17 64.8 1.4 3.6 3 1 0 4 4 3 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EMC93741.1 - 0.0033 17.6 5.9 0.0033 17.6 4.1 3.7 1 1 2 3 3 2 1 Protein of unknown function (DUF904) RTBV_P46 PF06216.6 EMC93741.1 - 0.0046 15.8 11.9 0.041 12.7 2.6 2.2 1 1 1 2 2 2 2 Rice tungro bacilliform virus P46 protein WEMBL PF05701.6 EMC93741.1 - 0.23 9.8 28.7 0.42 9.0 19.9 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 EMC93741.1 - 0.83 9.4 36.8 0.41 10.4 17.8 3.5 2 1 1 3 3 3 0 Tropomyosin like FemAB PF02388.11 EMC93741.1 - 1.2 7.7 8.9 1.9 7.0 6.2 1.2 1 0 0 1 1 1 0 FemAB family IncA PF04156.9 EMC93741.1 - 1.9 8.0 36.1 0.054 13.0 9.7 2.6 2 1 1 3 3 3 0 IncA protein Histone_HNS PF00816.16 EMC93741.1 - 1.9 9.0 16.8 2.3 8.7 0.1 3.5 2 1 1 3 3 3 0 H-NS histone family Filament PF00038.16 EMC93741.1 - 2.1 7.7 30.0 3.5 7.0 14.9 2.9 1 1 1 2 2 2 0 Intermediate filament protein DUF3584 PF12128.3 EMC93741.1 - 2.7 5.2 23.9 0.53 7.5 14.3 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 EMC93741.1 - 3.1 7.6 33.9 4.2 7.2 18.5 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALMT PF11744.3 EMC93741.1 - 3.6 6.1 3.9 5.1 5.6 2.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.1 EMC93741.1 - 4.6 6.1 12.9 8.4 5.2 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.7 EMC93741.1 - 5 6.9 7.7 2.6 7.8 3.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_S46 PF10459.4 EMC93741.1 - 7.1 4.9 13.1 9.9 4.4 9.1 1.1 1 0 0 1 1 1 0 Peptidase S46 DMPK_coil PF08826.5 EMC93741.1 - 8.8 6.3 32.7 0.052 13.4 2.6 4.3 4 1 1 5 5 5 0 DMPK coiled coil domain like ACC_central PF08326.7 EMC93743.1 - 5.1e-256 851.2 0.0 6.3e-256 851.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EMC93743.1 - 1.1e-178 594.6 0.0 1.7e-178 594.0 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EMC93743.1 - 8.4e-53 178.7 0.0 1.7e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EMC93743.1 - 3.5e-24 85.0 0.1 9.9e-24 83.5 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMC93743.1 - 8.3e-23 80.4 0.0 1.1e-20 73.5 0.0 3.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EMC93743.1 - 8.3e-16 57.3 0.1 2.2e-15 56.0 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EMC93743.1 - 1.1e-11 44.8 0.0 2.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC93743.1 - 7.3e-09 34.8 0.0 8.7e-05 21.4 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMC93743.1 - 3.5e-05 23.2 0.0 9.2e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EMC93743.1 - 0.00043 20.1 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 1 1 ATP-grasp domain ATP-grasp PF02222.17 EMC93743.1 - 0.0011 18.3 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EMC93743.1 - 0.019 14.4 0.0 0.94 8.9 0.0 2.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EMC93743.1 - 0.022 14.4 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like HlyD_2 PF12700.2 EMC93743.1 - 0.084 12.0 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Bot1p PF12298.3 EMC93745.1 - 2.6e-47 160.9 1.4 2.6e-47 160.9 1.0 1.7 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Nitroreductase PF00881.19 EMC93747.1 - 2.3e-12 47.0 0.0 2.8e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Synapsin_N PF10581.4 EMC93749.1 - 0.0071 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Synapsin N-terminal MFS_1 PF07690.11 EMC93750.1 - 2.8e-30 105.2 35.8 1.5e-29 102.8 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EMC93751.1 - 0.0011 18.5 1.5 0.0037 16.9 1.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC93751.1 - 0.0068 16.0 2.0 0.025 14.2 1.4 2.0 1 0 0 1 1 1 1 F-box domain Glyco_hydro_62 PF03664.8 EMC93752.1 - 9e-143 474.2 13.3 1e-142 474.0 9.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 ParA PF10609.4 EMC93754.1 - 1.8e-36 123.8 0.1 2.8e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMC93754.1 - 1.1e-16 60.8 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EMC93754.1 - 1.7e-06 27.3 0.0 1.5e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EMC93754.1 - 4e-06 26.0 0.3 0.00022 20.4 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 EMC93754.1 - 1.2e-05 25.0 0.6 0.0074 15.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_31 PF13614.1 EMC93754.1 - 1.9e-05 24.6 0.1 0.00011 22.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC93754.1 - 0.0067 15.8 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EMC93754.1 - 0.0079 15.0 0.2 0.013 14.2 0.1 1.2 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 EMC93754.1 - 0.051 12.9 0.2 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 YhjQ protein DUF258 PF03193.11 EMC93754.1 - 0.059 12.5 0.2 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 EMC93754.1 - 0.095 12.3 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase PQ-loop PF04193.9 EMC93755.1 - 7.9e-40 134.2 11.1 1e-20 72.9 1.0 2.5 2 0 0 2 2 2 2 PQ loop repeat Ni_hydr_CYTB PF01292.15 EMC93755.1 - 0.019 14.3 0.0 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF3671 PF12420.3 EMC93755.1 - 1.1 9.3 3.4 18 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function Ank_2 PF12796.2 EMC93756.1 - 7.5e-16 58.2 0.2 3.9e-13 49.5 0.1 2.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC93756.1 - 2.3e-14 52.3 0.3 6.4e-11 41.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EMC93756.1 - 7.3e-13 48.2 1.5 1.1e-09 38.2 0.4 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC93756.1 - 6.3e-12 45.6 0.0 3.7e-07 30.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC93756.1 - 1e-11 43.8 0.2 2.6e-08 33.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat GST_N_3 PF13417.1 EMC93758.1 - 5.4e-20 71.3 0.1 8.2e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC93758.1 - 1e-15 57.4 0.1 1.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC93758.1 - 2.2e-05 24.5 0.0 4.9e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain adh_short_C2 PF13561.1 EMC93765.1 - 7e-27 94.7 0.0 8.8e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC93765.1 - 5.9e-21 75.0 0.3 1.1e-20 74.1 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93765.1 - 2.8e-07 30.3 1.1 4.6e-06 26.4 0.8 2.1 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EMC93765.1 - 0.015 15.7 0.2 0.032 14.6 0.2 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent BTB PF00651.26 EMC93767.1 - 4e-09 36.4 0.0 1.6e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain p450 PF00067.17 EMC93770.1 - 3.8e-25 88.3 0.1 5.1e-24 84.6 0.0 2.2 2 1 0 2 2 2 1 Cytochrome P450 CobD_Cbib PF03186.8 EMC93770.1 - 0.029 13.4 0.6 0.065 12.3 0.0 1.7 2 0 0 2 2 2 0 CobD/Cbib protein Proteasome PF00227.21 EMC93771.1 - 3.9e-53 179.5 0.0 5.1e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC93771.1 - 2.6e-13 49.0 0.1 2.6e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WD40 PF00400.27 EMC93772.1 - 4.1e-24 83.5 3.1 1.8e-08 33.9 0.0 6.7 6 1 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EMC93772.1 - 5.7e-06 25.9 3.0 8.7e-05 22.0 1.1 2.4 2 0 0 2 2 2 1 PQQ-like domain CLTH PF10607.4 EMC93772.1 - 9.8e-05 22.0 0.1 0.00016 21.3 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PQQ PF01011.16 EMC93772.1 - 0.0064 15.9 0.2 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.1 EMC93772.1 - 0.037 14.2 8.8 0.087 13.1 0.1 4.2 3 1 1 4 4 4 0 PQQ-like domain IKI3 PF04762.7 EMC93772.1 - 0.16 9.7 0.0 3.1 5.4 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PLU-1 PF08429.6 EMC93773.1 - 7.7e-93 311.0 13.0 4.9e-92 308.3 9.2 1.9 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 EMC93773.1 - 6.3e-42 142.4 0.2 1.5e-41 141.2 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EMC93773.1 - 1.8e-26 91.8 0.8 3.9e-26 90.7 0.1 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EMC93773.1 - 3.7e-17 61.5 2.8 7.7e-17 60.5 1.9 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EMC93773.1 - 1.8e-16 59.9 10.0 4.8e-16 58.5 6.9 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EMC93773.1 - 2.4e-12 46.3 28.1 4.2e-08 32.7 6.2 3.0 3 0 0 3 3 3 2 PHD-finger AAA_13 PF13166.1 EMC93773.1 - 6.7 5.0 11.1 8.7 4.6 3.8 2.1 2 0 0 2 2 2 0 AAA domain GIY-YIG PF01541.19 EMC93774.1 - 1.5e-07 31.6 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EMC93774.1 - 0.00028 20.7 1.3 0.0005 19.9 0.9 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EMC93774.1 - 0.0021 17.8 3.2 0.0041 16.9 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 EMC93774.1 - 0.014 15.3 0.8 0.014 15.3 0.5 1.9 2 0 0 2 2 2 0 RING-like domain PHD PF00628.24 EMC93774.1 - 0.024 14.3 2.7 0.046 13.4 1.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 EMC93774.1 - 0.031 14.4 0.6 0.054 13.6 0.4 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC93774.1 - 0.032 14.2 0.2 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain MTHFR PF02219.12 EMC93775.1 - 1e-98 329.9 0.0 1.6e-98 329.3 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Thymidylate_kin PF02223.12 EMC93777.1 - 9.3e-48 162.0 0.0 1.1e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 EMC93777.1 - 0.00011 22.1 0.1 0.00033 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMC93777.1 - 0.00016 20.9 0.4 0.0029 16.8 0.0 2.5 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EMC93777.1 - 0.00023 21.1 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC93777.1 - 0.037 14.3 0.0 0.25 11.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EMC93777.1 - 0.061 14.1 0.1 0.12 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain TGT PF01702.13 EMC93778.1 - 3.2e-37 128.0 0.0 6e-37 127.1 0.0 1.4 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase LssY_C PF14067.1 EMC93779.1 - 0.11 11.4 0.1 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 LssY C-terminus FAD-oxidase_C PF02913.14 EMC93781.1 - 1.2e-58 198.3 0.0 1.9e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMC93781.1 - 5.7e-37 126.2 0.5 1.3e-36 125.0 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain TPR_10 PF13374.1 EMC93782.1 - 4.1e-74 242.6 13.6 8.4e-13 47.7 0.0 9.1 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 EMC93782.1 - 7.4e-55 182.8 18.7 1.3e-14 53.8 0.2 6.8 2 1 3 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 EMC93782.1 - 1.4e-13 50.2 6.9 0.029 14.0 0.1 5.8 5 1 0 5 5 5 3 TPR repeat TPR_7 PF13176.1 EMC93782.1 - 1.6e-13 49.3 14.6 0.0018 17.8 0.0 8.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_4 PF07721.9 EMC93782.1 - 1.8e-12 46.4 23.5 0.037 14.4 0.1 7.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMC93782.1 - 5.2e-12 44.8 10.4 0.078 12.6 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC93782.1 - 2.6e-11 42.5 21.1 0.051 13.5 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC93782.1 - 5.3e-10 39.6 21.7 0.68 10.6 0.0 8.1 3 1 5 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMC93782.1 - 1.3e-09 38.2 23.4 0.15 12.4 0.0 8.3 5 2 3 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC93782.1 - 2.6e-07 30.3 14.1 1.3 9.3 0.1 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat NB-ARC PF00931.17 EMC93782.1 - 8.4e-07 28.1 0.0 3.4e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 EMC93782.1 - 2.7e-06 27.4 28.6 1.9 9.3 0.1 9.3 7 2 2 9 9 9 1 Tetratricopeptide repeat AAA_22 PF13401.1 EMC93782.1 - 3.5e-06 27.1 0.0 1.4e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMC93782.1 - 2.9e-05 23.7 0.0 6.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.1 EMC93782.1 - 4.8e-05 22.8 2.1 2.7 7.9 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2664 PF10867.3 EMC93782.1 - 0.00012 22.6 1.6 5.6 7.6 0.0 4.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) TPR_6 PF13174.1 EMC93782.1 - 0.0039 17.5 19.6 4.1 8.0 0.1 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA_16 PF13191.1 EMC93782.1 - 0.0061 16.5 1.1 0.0061 16.5 0.8 3.3 3 2 1 4 4 2 1 AAA ATPase domain Rab5-bind PF09311.6 EMC93782.1 - 0.007 16.2 6.4 0.45 10.3 0.4 4.5 1 1 3 4 4 4 1 Rabaptin-like protein AAA_25 PF13481.1 EMC93782.1 - 0.012 15.0 2.2 0.018 14.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain PPR_3 PF13812.1 EMC93782.1 - 0.026 14.7 2.1 68 4.1 0.0 5.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Rad21_Rec8_N PF04825.8 EMC93782.1 - 0.061 13.2 0.5 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein Condensin2nSMC PF12422.3 EMC93782.1 - 0.073 12.8 0.3 1.4 8.6 0.1 2.6 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit PPR_1 PF12854.2 EMC93782.1 - 0.084 12.3 0.4 49 3.5 0.0 4.2 3 0 0 3 3 3 0 PPR repeat Bindin PF02084.10 EMC93782.1 - 0.11 12.5 2.0 19 5.1 0.0 3.7 2 2 2 4 4 4 0 Bindin DUF814 PF05670.8 EMC93782.1 - 0.13 12.1 10.2 9.8 6.1 0.0 6.3 3 1 5 8 8 7 0 Domain of unknown function (DUF814) TPR_3 PF07720.7 EMC93782.1 - 0.39 10.5 1.2 1.1e+02 2.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_1 PF00018.23 EMC93783.1 - 5.6e-09 35.2 0.1 5.6e-09 35.2 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC93783.1 - 1.4e-06 27.7 0.0 2.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC93783.1 - 1.7e-06 27.4 0.0 3.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2303 PF10065.4 EMC93783.1 - 0.051 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) DUF3278 PF11683.3 EMC93783.1 - 0.88 9.5 4.1 5.8 6.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) DUF4131 PF13567.1 EMC93783.1 - 1.6 8.1 8.8 0.3 10.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Herpes_LMP1 PF05297.6 EMC93783.1 - 5.2 5.8 7.6 1.2 7.9 0.2 2.1 1 1 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Catalase PF00199.14 EMC93784.1 - 2.2e-156 520.4 0.1 2.8e-156 520.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMC93784.1 - 2.3e-17 62.6 0.0 4.8e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Yqai PF09466.5 EMC93784.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein Yqai Abhydrolase_6 PF12697.2 EMC93786.1 - 1.8e-25 90.1 0.0 2.2e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93786.1 - 1.9e-12 47.2 0.1 1.5e-11 44.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93786.1 - 1.7e-08 34.3 0.0 4.4e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC93786.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Imm18 PF15566.1 EMC93786.1 - 0.026 13.8 0.2 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 18 DUF4048 PF13257.1 EMC93787.1 - 6e-15 55.5 28.7 2.2e-14 53.7 16.0 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4048) X PF00739.14 EMC93787.1 - 0.04 13.8 3.6 1.6 8.6 0.5 3.1 2 1 0 2 2 2 0 Trans-activation protein X GrpE PF01025.14 EMC93787.1 - 0.048 13.1 0.7 0.082 12.4 0.5 1.3 1 0 0 1 1 1 0 GrpE Glyco_hydro_2_C PF02836.12 EMC93789.1 - 3.2e-98 328.3 0.2 5.7e-98 327.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EMC93789.1 - 9.7e-56 188.7 0.0 1.7e-55 187.9 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EMC93789.1 - 8e-53 178.4 0.1 1.5e-52 177.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EMC93789.1 - 1.2e-11 45.0 0.1 2.5e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EMC93789.1 - 0.031 14.5 0.1 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Potyvirid-P3 PF13608.1 EMC93790.1 - 0.09 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein MFS_1 PF07690.11 EMC93791.1 - 3.9e-27 94.9 48.4 3.9e-27 94.9 33.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Exo_endo_phos PF03372.18 EMC93792.1 - 7.5e-20 71.9 0.5 1.1e-19 71.3 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 2OG-FeII_Oxy_2 PF13532.1 EMC93794.1 - 8.9e-11 41.9 0.0 2.3e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rad50_zn_hook PF04423.9 EMC93794.1 - 0.16 11.4 1.8 0.42 10.1 1.2 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif DEAD PF00270.24 EMC93796.1 - 2.1e-17 63.1 0.0 4.5e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC93796.1 - 5e-08 32.6 0.1 1.5e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC93796.1 - 2.3e-06 27.5 0.0 1.1e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EMC93796.1 - 0.17 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sedlin_N PF04628.8 EMC93797.1 - 1.6e-40 138.0 0.0 2.2e-40 137.5 0.0 1.2 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EMC93797.1 - 4.8e-06 26.3 0.0 0.00014 21.6 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family L31 PF09784.4 EMC93798.1 - 3.4e-43 145.9 2.3 4.6e-23 81.2 0.3 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L31 Pheromone PF08015.6 EMC93798.1 - 8.8 7.2 8.6 11 6.9 5.4 1.6 1 1 0 1 1 1 0 Fungal mating-type pheromone PMEI PF04043.10 EMC93801.1 - 0.033 14.0 0.3 0.033 14.0 0.2 3.0 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor 4HB_MCP_1 PF12729.2 EMC93801.1 - 0.084 12.2 0.8 0.36 10.1 0.3 2.2 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction COG2 PF06148.6 EMC93801.1 - 0.21 11.4 0.9 5.1 6.9 0.0 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2664 PF10867.3 EMC93801.1 - 1.5 9.5 8.1 10 6.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) Chlorosome_CsmC PF11098.3 EMC93801.1 - 5.1 6.8 10.3 5.7 6.6 0.0 4.0 3 2 0 3 3 3 0 Chlorosome envelope protein C RINGv PF12906.2 EMC93802.1 - 4.1e-15 55.5 13.5 7.6e-15 54.6 9.3 1.5 1 0 0 1 1 1 1 RING-variant domain Flagellin_C PF00700.16 EMC93802.1 - 0.062 13.4 0.6 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF1664 PF07889.7 EMC93802.1 - 1.6 8.5 2.4 16 5.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_2 PF13639.1 EMC93802.1 - 1.8 8.4 13.8 4 7.3 9.6 1.6 1 0 0 1 1 1 0 Ring finger domain Methyltransf_23 PF13489.1 EMC93803.1 - 1.3e-15 57.4 0.0 1.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC93803.1 - 3.2e-13 49.5 0.0 8.8e-13 48.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC93803.1 - 2.5e-11 43.9 0.0 4.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC93803.1 - 7e-11 42.6 0.0 8e-10 39.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC93803.1 - 3e-10 40.4 0.0 1.2e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC93803.1 - 2e-06 27.2 0.0 3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMC93803.1 - 5.3e-06 26.4 0.0 6.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC93803.1 - 1.8e-05 23.9 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EMC93803.1 - 8.6e-05 22.5 0.0 9.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EMC93803.1 - 8.6e-05 21.7 0.0 0.00018 20.7 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EMC93803.1 - 0.00011 22.4 0.0 0.00019 21.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EMC93803.1 - 0.00034 20.1 0.0 0.13 11.6 0.0 2.2 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 EMC93803.1 - 0.00056 19.0 0.0 0.00071 18.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EMC93803.1 - 0.00063 18.9 0.0 0.00089 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EMC93803.1 - 0.0024 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 EMC93803.1 - 0.0039 16.4 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF938 PF06080.7 EMC93803.1 - 0.0059 16.1 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 EMC93803.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 EMC93803.1 - 0.013 14.6 0.0 0.033 13.3 0.0 1.8 1 1 1 2 2 2 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EMC93803.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EMC93803.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_17 PF12692.2 EMC93803.1 - 0.032 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_32 PF13679.1 EMC93803.1 - 0.044 13.4 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EMC93803.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase ArsB PF02040.10 EMC93804.1 - 5e-15 55.3 19.0 6.4e-13 48.4 3.5 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein TPR_11 PF13414.1 EMC93805.1 - 6.7e-38 128.1 18.3 7.1e-11 41.6 0.1 6.7 5 1 2 7 7 7 6 TPR repeat TPR_1 PF00515.23 EMC93805.1 - 1.1e-37 126.0 4.3 1.5e-06 27.5 0.0 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMC93805.1 - 2.5e-36 120.6 13.3 3e-06 26.7 0.0 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat Apc3 PF12895.2 EMC93805.1 - 2.8e-29 101.0 11.5 1.5e-18 66.7 0.1 4.9 3 1 1 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EMC93805.1 - 6.7e-29 99.6 15.9 3.4e-06 26.8 0.1 7.7 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 EMC93805.1 - 1.1e-23 81.1 0.6 0.002 17.7 0.0 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC93805.1 - 1.4e-23 82.9 22.3 2.8e-07 31.0 0.0 7.4 5 3 3 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMC93805.1 - 2.3e-20 71.2 19.2 0.00038 20.8 0.0 10.2 6 3 5 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMC93805.1 - 1.4e-19 70.1 15.3 9.1e-05 22.7 0.1 6.8 5 2 2 7 7 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 EMC93805.1 - 2.6e-15 55.2 12.8 0.085 13.1 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC93805.1 - 5.4e-14 50.7 10.9 0.046 13.5 0.1 8.5 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMC93805.1 - 6.2e-10 38.8 14.1 0.048 14.1 0.3 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 EMC93805.1 - 3.8e-07 29.4 8.8 0.11 11.5 0.0 4.9 3 1 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMC93805.1 - 7e-06 25.8 15.0 0.002 17.9 0.6 6.1 5 3 2 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.5 EMC93805.1 - 0.0069 15.1 0.6 1.1 7.9 0.0 3.1 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.7 EMC93805.1 - 0.008 15.9 0.2 6.8 6.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat YfiO PF13525.1 EMC93805.1 - 0.018 14.4 0.4 0.063 12.7 0.1 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein DUF788 PF05620.6 EMC93806.1 - 1e-45 155.6 0.0 1.2e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) YwiC PF14256.1 EMC93806.1 - 0.026 14.6 2.7 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 YwiC-like protein Acetyltransf_2 PF00797.12 EMC93807.1 - 1.6e-37 129.3 0.2 2.2e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 N-acetyltransferase KRTAP7 PF15034.1 EMC93807.1 - 0.17 12.5 0.7 0.31 11.7 0.5 1.3 1 0 0 1 1 1 0 KRTAP type 7 family FAD_binding_4 PF01565.18 EMC93808.1 - 6.6e-27 93.6 0.3 1.1e-26 92.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMC93808.1 - 0.0017 18.2 0.1 0.0059 16.4 0.1 2.0 1 0 0 1 1 1 1 Berberine and berberine like EthD PF07110.6 EMC93809.1 - 5.8e-21 75.2 0.6 7.2e-21 74.9 0.4 1.1 1 0 0 1 1 1 1 EthD domain CoA_transf_3 PF02515.12 EMC93812.1 - 2.5e-50 170.3 0.0 3.3e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Peroxidase_2 PF01328.12 EMC93813.1 - 1.3e-16 60.2 0.1 1.8e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 DUF1772 PF08592.6 EMC93815.1 - 2.4e-16 59.7 1.8 3.3e-16 59.2 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF204 PF02659.10 EMC93815.1 - 0.13 12.4 3.2 0.23 11.6 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF NAD_binding_10 PF13460.1 EMC93816.1 - 3e-16 59.9 0.1 3.9e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMC93816.1 - 4.8e-06 26.8 0.0 9.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EMC93816.1 - 3.1e-05 23.3 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EMC93816.1 - 0.0037 16.2 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EMC93816.1 - 0.0041 17.0 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EMC93816.1 - 0.0044 15.9 0.0 0.13 11.1 0.0 2.5 3 0 0 3 3 3 1 Male sterility protein Epimerase PF01370.16 EMC93816.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Halo_GVPC PF05465.8 EMC93817.1 - 0.26 11.2 0.1 0.26 11.2 0.0 2.9 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat IMS PF00817.15 EMC93818.1 - 3.7e-42 143.6 0.0 5.4e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMC93818.1 - 2.7e-11 43.4 0.0 5.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMC93818.1 - 0.0018 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 IMS family HHH motif zf-FPG_IleRS PF06827.9 EMC93818.1 - 0.025 14.2 0.3 0.025 14.2 0.2 1.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF2052 PF09747.4 EMC93819.1 - 2.3e-23 83.0 12.0 1.3e-21 77.3 8.3 2.0 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) YEATS PF03366.11 EMC93820.1 - 8e-25 86.3 0.0 1.2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 YEATS family SRP54 PF00448.17 EMC93821.1 - 1.9e-75 252.6 1.1 4e-75 251.5 0.7 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EMC93821.1 - 5.9e-26 90.7 3.6 5.9e-26 90.7 2.5 4.4 3 2 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.14 EMC93821.1 - 1.1e-12 47.9 0.3 2.4e-12 46.7 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EMC93821.1 - 7.2e-08 32.0 0.2 2.4e-07 30.3 0.1 1.9 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMC93821.1 - 3.3e-06 27.0 0.0 8.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EMC93821.1 - 7.6e-06 25.6 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EMC93821.1 - 1.3e-05 24.7 0.1 5.1e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.2 EMC93821.1 - 0.00054 19.5 0.0 0.00096 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EMC93821.1 - 0.00083 20.1 0.0 0.0023 18.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_31 PF13614.1 EMC93821.1 - 0.00085 19.2 0.0 1.7 8.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EMC93821.1 - 0.0011 19.1 0.0 0.0054 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EMC93821.1 - 0.0032 17.1 0.2 0.0079 15.8 0.0 1.7 2 0 0 2 2 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.12 EMC93821.1 - 0.013 14.8 0.3 0.034 13.5 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase TrwB_AAD_bind PF10412.4 EMC93821.1 - 0.017 13.7 0.0 0.049 12.2 0.0 1.7 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain 6PF2K PF01591.13 EMC93821.1 - 0.018 14.0 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_18 PF13238.1 EMC93821.1 - 0.018 15.3 0.3 0.11 12.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMC93821.1 - 0.029 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.12 EMC93821.1 - 0.055 13.0 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.16 EMC93821.1 - 0.096 11.9 0.0 0.29 10.3 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family Spectrin PF00435.16 EMC93821.1 - 0.11 12.8 0.8 0.29 11.4 0.1 2.0 2 0 0 2 2 2 0 Spectrin repeat AAA_28 PF13521.1 EMC93821.1 - 0.12 12.3 0.1 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Rrp15p PF07890.7 EMC93822.1 - 7.7e-37 126.2 8.7 7.7e-37 126.2 6.0 2.1 2 0 0 2 2 2 1 Rrp15p NUT_C PF12882.2 EMC93822.1 - 0.066 12.8 0.6 0.15 11.6 0.4 1.6 1 0 0 1 1 1 0 NUT protein C terminal SDA1 PF05285.7 EMC93822.1 - 0.18 11.0 18.3 0.26 10.5 12.7 1.4 1 1 0 1 1 1 0 SDA1 RRN3 PF05327.6 EMC93822.1 - 0.83 7.6 10.0 1.1 7.3 6.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 EMC93822.1 - 1 9.3 9.3 2 8.4 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Peptidase_S64 PF08192.6 EMC93822.1 - 1.7 6.9 6.6 2.3 6.4 4.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 NMT1 PF09084.6 EMC93823.1 - 0.04 13.5 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 NMT1/THI5 like DUF3310 PF11753.3 EMC93823.1 - 0.091 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) FixP_N PF14715.1 EMC93823.1 - 0.21 11.0 2.2 0.36 10.2 1.5 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP SAD_SRA PF02182.12 EMC93824.1 - 7.8e-32 109.7 0.1 1.2e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain FLILHELTA PF10306.4 EMC93825.1 - 1.4e-26 92.3 0.0 2.2e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EMC93825.1 - 0.00096 19.4 0.4 0.0011 19.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF1138 PF06592.8 EMC93825.1 - 0.037 14.0 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) ATP-synt_ab PF00006.20 EMC93826.1 - 2.1e-112 373.8 0.0 4.9e-112 372.6 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_M PF01031.15 EMC93826.1 - 6.9e-104 346.7 0.0 6.9e-104 346.7 0.0 2.4 4 0 0 4 4 4 1 Dynamin central region Dynamin_N PF00350.18 EMC93826.1 - 7.2e-56 188.6 0.0 1.5e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EMC93826.1 - 7.6e-29 99.4 8.2 1.6e-28 98.3 5.7 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain ATP-synt_ab_C PF00306.22 EMC93826.1 - 1.3e-19 70.7 0.3 4.3e-19 69.0 0.2 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMC93826.1 - 5.6e-15 55.3 1.6 1.6e-14 53.8 1.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MMR_HSR1 PF01926.18 EMC93826.1 - 0.0009 19.1 0.2 0.0093 15.9 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMC93826.1 - 0.018 15.0 0.0 12 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 EMC93826.1 - 0.019 15.4 0.0 0.085 13.3 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EMC93826.1 - 0.061 13.2 0.1 5.3 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Aldo_ket_red PF00248.16 EMC93828.1 - 1.3e-53 181.7 0.0 1.5e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NMO PF03060.10 EMC93829.1 - 2.8e-61 207.5 0.0 5.5e-61 206.5 0.0 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMC93829.1 - 2.7e-11 42.9 0.0 2.8e-05 23.2 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMC93829.1 - 0.025 13.5 0.3 0.22 10.4 0.2 2.1 1 1 0 1 1 1 0 Conserved region in glutamate synthase FMN_dh PF01070.13 EMC93829.1 - 0.027 13.3 0.0 0.059 12.1 0.0 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1902 PF08972.6 EMC93829.1 - 0.065 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) NanE PF04131.9 EMC93829.1 - 0.085 11.8 0.4 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EMC93829.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein FAT PF02259.18 EMC93830.1 - 6.3e-70 235.9 10.6 1.3e-69 234.8 7.4 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EMC93830.1 - 5.7e-24 84.8 0.4 1.7e-23 83.3 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EMC93830.1 - 4.1e-08 32.5 2.8 8.1e-08 31.5 0.2 2.7 2 0 0 2 2 2 1 FATC domain TPR_2 PF07719.12 EMC93830.1 - 0.027 14.3 0.9 15 5.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC93830.1 - 0.91 9.2 6.4 10 5.8 0.3 3.5 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.1 EMC93830.1 - 2 8.3 4.6 20 5.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_15 PF01793.11 EMC93831.1 - 8.2e-134 445.7 5.1 1e-133 445.4 3.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EMC93832.1 - 2.1e-43 148.4 1.0 3.1e-43 147.9 0.7 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EMC93832.1 - 2.3e-07 29.3 0.0 4.2e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Methyltransf_11 PF08241.7 EMC93833.1 - 3.3e-17 62.7 0.0 1.2e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC93833.1 - 3.1e-15 56.0 0.0 5e-15 55.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC93833.1 - 5.1e-14 52.8 0.0 7.2e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EMC93833.1 - 2e-11 44.2 0.0 6.4e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC93833.1 - 2.3e-10 40.4 0.0 3.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC93833.1 - 4.4e-10 39.8 0.0 2.6e-09 37.3 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC93833.1 - 7.4e-10 38.3 0.0 2.4e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMC93833.1 - 5.1e-07 29.2 0.0 1.1e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMC93833.1 - 8.4e-06 25.8 0.0 0.00013 21.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC93833.1 - 5.1e-05 22.4 0.0 8.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EMC93833.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EMC93833.1 - 0.0021 17.2 0.0 0.0034 16.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EMC93833.1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.8 EMC93833.1 - 0.012 14.7 1.0 0.052 12.6 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CoaE PF01121.15 EMC93834.1 - 1e-42 145.5 0.0 7.5e-42 142.7 0.0 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 EMC93834.1 - 7.5e-06 25.8 0.0 0.00025 20.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC93834.1 - 9.8e-05 23.1 0.3 0.00065 20.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMC93834.1 - 0.077 12.9 0.9 0.45 10.4 0.0 2.4 3 1 0 3 3 3 0 AAA domain SKI PF01202.17 EMC93834.1 - 0.077 12.8 0.0 1.8 8.4 0.0 2.4 2 1 0 2 2 2 0 Shikimate kinase PfkB PF00294.19 EMC93836.1 - 1.4e-54 185.2 1.9 1.6e-54 185.0 1.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase FAD_binding_3 PF01494.14 EMC93839.1 - 1.2e-13 50.8 0.3 3.8e-12 45.9 0.2 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMC93839.1 - 0.0024 17.8 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TPR_11 PF13414.1 EMC93840.1 - 8.2e-22 76.6 21.0 2.9e-07 30.0 0.3 7.5 6 1 1 7 7 7 5 TPR repeat Apc3 PF12895.2 EMC93840.1 - 4.1e-20 71.6 13.2 2e-14 53.4 0.9 5.7 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EMC93840.1 - 4.4e-20 69.9 17.3 0.0022 17.7 0.2 10.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC93840.1 - 4.5e-17 62.1 19.1 4.3e-07 30.1 0.3 8.0 5 2 5 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EMC93840.1 - 1.4e-15 56.1 11.3 0.00027 20.4 0.3 8.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC93840.1 - 1.1e-13 51.4 26.2 0.0024 18.4 0.0 7.6 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC93840.1 - 5.2e-12 44.6 0.5 0.056 13.2 0.1 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC93840.1 - 1.7e-10 40.6 24.0 4.6e-07 29.6 0.4 8.0 6 2 1 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC93840.1 - 7.1e-10 38.6 28.6 0.019 15.5 0.9 10.7 7 3 5 12 12 12 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC93840.1 - 1.9e-05 24.1 15.7 0.067 13.0 0.2 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC93840.1 - 0.00055 20.2 20.4 1.2 9.7 0.1 7.7 8 1 1 9 9 7 2 Tetratricopeptide repeat PPR PF01535.15 EMC93840.1 - 0.0013 18.5 0.7 0.58 10.2 0.0 4.4 4 0 0 4 4 3 1 PPR repeat TPR_17 PF13431.1 EMC93840.1 - 0.0016 18.4 4.0 16 5.9 0.1 6.1 6 1 1 7 7 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 EMC93840.1 - 0.0023 17.0 5.1 1.7 7.6 0.1 4.6 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.9 EMC93840.1 - 0.008 16.5 20.0 0.048 14.1 2.3 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC93840.1 - 0.014 15.3 1.3 0.014 15.3 0.9 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Apc5 PF12862.2 EMC93840.1 - 0.025 14.4 1.4 0.14 12.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 EMC93840.1 - 0.046 13.8 6.4 1.5 8.9 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMC93840.1 - 7.7 6.4 21.0 13 5.7 0.6 6.9 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMC93840.1 - 9.5 6.1 11.1 11 5.9 0.0 4.6 5 2 0 5 5 5 0 Tetratricopeptide repeat DUF572 PF04502.8 EMC93841.1 - 1.6e-75 254.3 17.5 1.9e-75 254.1 12.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Lar_restr_allev PF14354.1 EMC93841.1 - 0.0071 16.6 0.9 1.4 9.2 0.2 2.6 1 1 1 2 2 2 2 Restriction alleviation protein Lar Benyvirus_14KDa PF07255.6 EMC93841.1 - 0.063 13.1 0.9 0.17 11.7 0.7 1.7 1 1 0 1 1 1 0 Benyvirus 14KDa protein DNA_RNApol_7kD PF03604.8 EMC93841.1 - 0.15 11.5 1.7 7.2 6.1 0.1 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-dskA_traR PF01258.12 EMC93841.1 - 0.38 10.5 0.1 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DUF4207 PF13904.1 EMC93841.1 - 0.49 9.7 8.3 1 8.7 5.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) DUF1014 PF06244.7 EMC93841.1 - 3.6 7.8 9.6 2.4 8.3 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Nop14 PF04147.7 EMC93841.1 - 4.5 5.0 18.3 6 4.6 12.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1996 PF09362.5 EMC93842.1 - 6.9e-68 228.8 0.8 9.1e-68 228.4 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BCS1_N PF08740.6 EMC93843.1 - 1.6e-35 122.4 1.1 2.5e-35 121.8 0.8 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMC93843.1 - 1.5e-08 34.9 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC93843.1 - 0.00028 21.6 0.1 0.0022 18.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain P2_Phage_GpR PF06891.6 EMC93843.1 - 0.0042 16.8 0.2 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 P2 phage tail completion protein R (GpR) AAA_25 PF13481.1 EMC93843.1 - 0.011 15.1 0.0 0.051 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EMC93843.1 - 0.016 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EMC93843.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 EMC93843.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMC93843.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMC93843.1 - 0.14 12.1 0.9 0.31 10.9 0.2 2.1 2 1 0 2 2 2 0 AAA ATPase domain Ribosomal_L4 PF00573.17 EMC93844.1 - 1.6e-43 148.3 0.2 2.1e-43 147.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EMC93844.1 - 8.3e-26 89.6 0.2 8.3e-26 89.6 0.1 1.7 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain TAFII28 PF04719.9 EMC93845.1 - 8.1e-17 60.8 0.0 9.7e-16 57.3 0.0 2.1 2 0 0 2 2 2 1 hTAFII28-like protein conserved region zf-DHHC PF01529.15 EMC93846.1 - 7.1e-28 97.1 0.0 1.3e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Homeobox_KN PF05920.6 EMC93849.1 - 1.9e-14 53.0 0.7 1.9e-14 53.0 0.5 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EMC93849.1 - 3.5e-10 39.3 0.3 6.6e-10 38.4 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain API5 PF05918.6 EMC93852.1 - 0.29 9.5 6.0 0.3 9.5 4.1 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2404 PF10296.4 EMC93854.1 - 1.7e-05 24.8 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) APG17 PF04108.7 EMC93855.1 - 5.8e-87 292.1 4.1 7.2e-87 291.8 2.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Herpes_UL36 PF03586.8 EMC93855.1 - 0.0045 16.1 3.9 0.017 14.2 1.5 2.4 2 1 0 2 2 2 1 Herpesvirus UL36 tegument protein GAS PF13851.1 EMC93855.1 - 0.0047 16.1 3.4 0.76 8.9 0.3 2.8 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EMC93855.1 - 0.008 15.3 9.7 0.21 10.7 0.5 2.7 2 1 0 2 2 2 2 Reovirus sigma C capsid protein DUF2130 PF09903.4 EMC93855.1 - 0.014 14.1 3.4 7 5.2 0.0 3.7 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2130) MCPsignal PF00015.16 EMC93855.1 - 0.047 13.2 6.4 0.093 12.2 0.5 2.6 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Med9 PF07544.8 EMC93855.1 - 0.07 12.8 0.9 5.9 6.6 0.0 3.4 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Bacillus_HBL PF05791.6 EMC93855.1 - 0.16 11.2 2.9 10 5.4 0.2 3.6 2 2 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DASH_Spc19 PF08287.6 EMC93855.1 - 0.2 11.2 4.3 1.1 8.8 0.0 3.7 2 1 1 3 3 3 0 Spc19 APG6 PF04111.7 EMC93855.1 - 0.37 9.8 7.8 0.43 9.5 3.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EMC93855.1 - 0.83 9.2 8.2 8.5 5.9 2.4 2.8 2 1 0 2 2 2 0 IncA protein WXG100 PF06013.7 EMC93855.1 - 1.4 8.9 13.7 0.52 10.3 0.3 4.7 4 2 1 5 5 4 0 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.7 EMC93855.1 - 1.7 8.4 8.6 7.2 6.4 2.5 3.3 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FTO_CTD PF12934.2 EMC93855.1 - 2.1 7.8 6.3 8.2 5.9 0.4 2.6 1 1 1 2 2 2 0 FTO C-terminal domain Cob_adeno_trans PF01923.13 EMC93855.1 - 4.1 7.1 10.5 2.5 7.8 0.5 3.2 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Fib_alpha PF08702.5 EMC93855.1 - 7 6.7 6.5 5.1 7.2 0.5 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.1 EMC93855.1 - 8.5 5.7 11.6 5.9 6.2 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) WD40 PF00400.27 EMC93856.1 - 2.3e-62 204.8 19.9 4.1e-10 39.1 0.2 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EMC93856.1 - 9.2e-12 44.5 0.2 2e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC93856.1 - 5.9e-11 41.7 0.2 1.4e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EMC93856.1 - 1.6e-09 36.5 12.2 0.079 11.0 0.1 5.5 3 1 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC93856.1 - 2.3e-06 26.6 0.8 0.55 8.9 0.0 4.5 2 2 1 3 3 3 2 Nup133 N terminal like Abhydrolase_6 PF12697.2 EMC93857.1 - 4.9e-21 75.6 0.0 6.3e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93857.1 - 7.3e-06 25.7 0.0 2.5e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC93857.1 - 1.6e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3 PF13350.1 EMC93858.1 - 7.5e-39 133.6 0.0 1.5e-38 132.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EMC93858.1 - 4.1e-12 46.0 0.0 8.7e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EMC93858.1 - 1.2e-06 28.0 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EMC93858.1 - 2.2e-05 23.8 0.0 6.2e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EMC93858.1 - 0.011 15.2 0.0 0.037 13.5 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC93858.1 - 0.051 13.6 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate F-box PF00646.28 EMC93859.1 - 0.00042 19.9 0.8 0.00042 19.9 0.5 1.8 2 0 0 2 2 2 1 F-box domain Ins_P5_2-kin PF06090.7 EMC93860.1 - 1.4e-45 155.7 0.0 3.5e-45 154.3 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF77 PF01910.12 EMC93861.1 - 1.6e-28 98.1 0.1 1.9e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Beta-lactamase PF00144.19 EMC93862.1 - 3.6e-39 134.7 0.0 5.2e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.27 EMC93863.1 - 3.4e-10 39.4 2.1 4.8e-06 26.2 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 EMC93863.1 - 0.13 11.3 0.0 3.1 6.8 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EMC93863.1 - 0.17 10.6 0.0 0.52 8.9 0.0 1.8 1 1 0 1 1 1 0 Nup133 N terminal like Septin PF00735.13 EMC93864.1 - 2.3e-105 351.6 0.1 5.6e-105 350.3 0.0 1.6 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.18 EMC93864.1 - 0.00019 21.3 2.2 0.49 10.1 0.0 2.9 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 EMC93864.1 - 0.00019 21.3 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC93864.1 - 0.0092 15.1 0.2 0.033 13.3 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC93864.1 - 0.014 16.2 1.8 0.24 12.2 0.1 2.7 2 2 0 2 2 2 0 AAA domain Miro PF08477.8 EMC93864.1 - 0.047 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EMC93864.1 - 0.11 12.6 0.2 0.43 10.7 0.0 2.1 2 2 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EMC93864.1 - 0.12 11.7 0.0 2.1 7.7 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Prominin PF05478.6 EMC93864.1 - 1.5 6.2 4.4 2.1 5.7 3.1 1.1 1 0 0 1 1 1 0 Prominin Ribosomal_S16 PF00886.14 EMC93865.1 - 2.7e-21 75.0 0.0 3.5e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 DUF2808 PF10989.3 EMC93866.1 - 0.064 12.8 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) PHD PF00628.24 EMC93867.1 - 1.1e-10 41.0 4.8 2.8e-10 39.6 3.4 1.7 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMC93867.1 - 0.0023 17.1 4.3 0.0037 16.5 3.0 1.3 1 0 0 1 1 1 1 PHD-finger UIM PF02809.15 EMC93867.1 - 0.071 12.7 2.3 0.19 11.3 1.6 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase PF00069.20 EMC93869.1 - 5.3e-56 189.6 0.0 6.9e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93869.1 - 1.4e-27 96.3 0.0 5.3e-27 94.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC93869.1 - 0.00027 19.9 0.0 0.00057 18.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC93869.1 - 0.0024 16.9 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Spermine_synth PF01564.12 EMC93870.1 - 5.3e-05 22.2 0.0 8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EMC93870.1 - 0.0015 18.5 0.2 0.0039 17.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain ZYG-11_interact PF05884.7 EMC93870.1 - 0.087 11.9 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3635 PF12330.3 EMC93871.1 - 4.3e-09 36.3 1.3 3.1e-06 27.1 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3635) RRM_1 PF00076.17 EMC93872.1 - 5e-17 61.3 0.0 7.2e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC93872.1 - 1.4e-12 47.4 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC93872.1 - 7.2e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EMC93872.1 - 2.5e-05 24.6 5.6 2.5e-05 24.6 3.9 2.8 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Isochorismatase PF00857.15 EMC93873.1 - 5.5e-47 159.9 0.0 7.2e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MIP PF00230.15 EMC93876.1 - 1.5e-46 158.7 16.9 1.8e-46 158.4 11.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein Response_reg PF00072.19 EMC93878.1 - 9.8e-21 73.8 0.0 8.1e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain DRY_EERY PF09750.4 EMC93878.1 - 0.04 14.0 2.9 0.1 12.7 2.0 1.6 1 0 0 1 1 1 0 Alternative splicing regulator DUF3605 PF12239.3 EMC93879.1 - 2.6e-56 189.8 0.0 3.1e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Y1_Tnp PF01797.11 EMC93879.1 - 0.13 12.1 0.1 0.98 9.2 0.1 2.1 1 1 1 2 2 2 0 Transposase IS200 like FAD_binding_6 PF00970.19 EMC93880.1 - 5.8e-27 93.7 0.0 1.6e-26 92.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMC93880.1 - 8.5e-26 90.6 0.0 1.5e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMC93880.1 - 8.8e-07 28.9 0.0 6.1e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMC93880.1 - 0.0053 16.7 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Oxidored_FMN PF00724.15 EMC93881.1 - 5.1e-85 285.4 0.0 6.3e-85 285.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 EMC93882.1 - 1e-45 155.9 44.6 7.5e-45 153.1 30.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC93882.1 - 6.8e-22 77.4 8.1 6.8e-22 77.4 5.6 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC93882.1 - 7.8e-15 54.3 12.9 7.8e-15 54.3 9.0 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter Polysacc_deac_1 PF01522.16 EMC93883.1 - 2.9e-15 55.9 0.0 4.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.13 EMC93884.1 - 2.1e-22 79.2 0.3 3.5e-22 78.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93884.1 - 1e-07 31.6 12.2 2.1e-07 30.7 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 EMC93885.1 - 7.6e-85 285.0 46.6 8.9e-85 284.8 32.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.16 EMC93886.1 - 1.7e-73 247.9 0.1 2.1e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Abhydrolase_3 PF07859.8 EMC93887.1 - 9.7e-31 106.9 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMC93887.1 - 0.00013 20.7 0.0 0.00015 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EMC93887.1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family HET PF06985.6 EMC93889.1 - 3.7e-06 27.1 0.0 8.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EMC93890.1 - 4.6e-13 49.5 0.3 5.1e-13 49.3 0.2 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MCM PF00493.18 EMC93891.1 - 9.5e-144 478.2 0.1 1.3e-143 477.7 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMC93891.1 - 7.3e-18 65.2 0.2 2e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMC93891.1 - 2.7e-06 26.7 0.0 0.00026 20.2 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMC93891.1 - 2.5e-05 24.0 0.0 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMC93891.1 - 0.00087 18.8 0.0 0.0035 16.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GntR PF00392.16 EMC93891.1 - 0.0061 15.9 2.0 0.088 12.2 1.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Sigma54_activat PF00158.21 EMC93891.1 - 0.03 13.7 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps54 PF07928.7 EMC93892.1 - 1.5e-41 141.6 0.0 3.8e-41 140.3 0.0 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EMC93892.1 - 4.6e-07 29.0 0.4 1.7e-06 27.1 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Atg14 PF10186.4 EMC93892.1 - 0.0063 15.5 0.6 0.011 14.7 0.4 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EMC93892.1 - 0.14 10.8 1.8 0.11 11.1 0.2 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.6 EMC93892.1 - 0.26 11.1 1.4 0.89 9.4 1.0 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 LUC7 PF03194.10 EMC93892.1 - 0.81 9.1 3.2 1.5 8.2 1.1 1.9 2 0 0 2 2 2 0 LUC7 N_terminus FliJ PF02050.11 EMC93892.1 - 6.2 6.8 8.8 0.14 12.1 0.4 2.5 3 0 0 3 3 3 0 Flagellar FliJ protein AMP-binding PF00501.23 EMC93893.1 - 2.3e-73 247.0 0.0 2.9e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC93893.1 - 1.8e-13 51.2 0.5 3.7e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DGC PF08859.6 EMC93895.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 DGC domain DUF2659 PF10858.3 EMC93896.1 - 0.059 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) Fungal_trans PF04082.13 EMC93897.1 - 5.3e-16 58.2 0.1 8.8e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93897.1 - 1.8e-06 27.7 7.2 3.3e-06 26.9 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.15 EMC93898.1 - 1e-38 133.7 1.4 1.4e-38 133.3 0.5 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase HET PF06985.6 EMC93899.1 - 6.1e-30 104.2 0.2 7.7e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COG2 PF06148.6 EMC93901.1 - 1.5e-29 102.5 1.0 2.9e-28 98.4 0.0 2.5 2 1 1 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EMC93901.1 - 1.5e-06 27.9 0.0 6.1e-06 25.9 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EMC93901.1 - 0.011 15.6 0.0 0.031 14.2 0.0 1.8 2 1 0 2 2 2 0 Golgi transport complex subunit 5 NUDIX PF00293.23 EMC93902.1 - 4.7e-16 58.6 0.1 1.3e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.6 EMC93902.1 - 2.7e-12 46.8 0.0 5.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EMC93902.1 - 1.6e-06 27.4 1.5 3e-06 26.6 1.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ribosomal_L1 PF00687.16 EMC93903.1 - 1.6e-29 102.8 0.0 1.8e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Adap_comp_sub PF00928.16 EMC93905.1 - 4.1e-91 304.6 0.0 5.7e-91 304.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMC93905.1 - 3.7e-10 39.6 0.2 5.9e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L27 PF01016.14 EMC93906.1 - 1.9e-26 91.6 0.2 2.8e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein AMP-binding PF00501.23 EMC93908.1 - 4.3e-45 153.8 0.0 6.2e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme p450 PF00067.17 EMC93909.1 - 7.9e-43 146.6 0.0 2.4e-42 145.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_88 PF07470.8 EMC93910.1 - 7.6e-16 58.0 2.0 1.1e-15 57.5 1.4 1.3 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 TrkH PF02386.11 EMC93911.1 - 6.5e-122 406.5 9.0 1.4e-118 395.5 5.0 2.1 2 0 0 2 2 2 2 Cation transport protein GATase_5 PF13507.1 EMC93912.1 - 1.7e-94 315.5 0.0 2.4e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EMC93912.1 - 3.2e-40 137.6 1.6 2e-19 70.1 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EMC93912.1 - 3e-26 91.4 0.1 4.4e-25 87.7 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain TruB_C PF09142.6 EMC93912.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Tau95 PF09734.4 EMC93914.1 - 3.5e-46 157.9 0.0 5.1e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Polyketide_cyc2 PF10604.4 EMC93914.1 - 0.082 13.0 0.1 13 5.9 0.0 2.7 3 0 0 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport B56 PF01603.15 EMC93915.1 - 2.7e-172 573.0 5.1 3.2e-172 572.7 3.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 EMC93915.1 - 0.16 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Dynamin family COX5A PF02284.11 EMC93916.1 - 1.7e-39 134.1 0.4 2e-39 133.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 EMC93916.1 - 0.026 12.8 0.5 0.61 8.3 0.0 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 ELO PF01151.13 EMC93917.1 - 3.3e-61 206.7 19.5 3.9e-61 206.5 13.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pkinase PF00069.20 EMC93918.1 - 1.5e-39 135.7 0.0 2.2e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC93918.1 - 6.3e-23 81.1 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 EMC93920.1 - 3.8e-38 128.0 7.1 1.2e-07 31.2 0.9 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMC93920.1 - 3.7e-26 90.8 0.2 8.5e-26 89.6 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3312 PF11768.3 EMC93920.1 - 0.00048 18.4 0.0 0.017 13.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) DUF1020 PF06255.8 EMC93920.1 - 0.043 13.0 0.1 0.079 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1020) IKI3 PF04762.7 EMC93920.1 - 0.095 10.4 0.3 2.1 6.0 0.0 2.2 2 1 1 3 3 3 0 IKI3 family DUF3995 PF13160.1 EMC93921.1 - 0.056 13.4 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) zf-H2C2_5 PF13909.1 EMC93922.1 - 0.0039 17.3 1.8 0.0039 17.3 1.3 2.2 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EMC93922.1 - 0.98 9.8 13.2 0.19 12.0 0.6 3.6 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.21 EMC93922.1 - 1.4 9.3 13.1 0.25 11.7 0.1 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type Ank PF00023.25 EMC93923.1 - 2.4e-14 52.3 0.1 1.4e-09 37.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMC93923.1 - 1e-13 51.4 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC93923.1 - 4.5e-12 46.1 0.1 7.3e-06 26.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC93923.1 - 6.3e-12 45.3 0.1 4.2e-10 39.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC93923.1 - 6.7e-10 38.2 0.0 5.1e-06 26.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat SKIP_SNW PF02731.10 EMC93924.1 - 2.5e-65 218.7 8.5 2.5e-65 218.7 5.9 2.2 2 0 0 2 2 2 1 SKIP/SNW domain UPF0029 PF01205.14 EMC93925.1 - 1e-31 108.8 0.0 1.4e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EMC93925.1 - 1.9e-07 30.9 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain p450 PF00067.17 EMC93926.1 - 1.1e-56 192.3 0.0 1.4e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SEP PF08059.8 EMC93927.1 - 2.2e-26 91.9 0.0 4.8e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EMC93927.1 - 6e-16 58.2 0.0 1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EMC93927.1 - 6.2e-14 51.2 0.3 1.1e-13 50.5 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EMC93927.1 - 0.0015 18.3 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Anophelin PF10731.4 EMC93927.1 - 4.3 7.5 6.8 0.94 9.6 1.5 2.3 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito TOM13 PF08219.6 EMC93928.1 - 2.9e-30 103.8 0.0 3.9e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 DHDPS PF00701.17 EMC93929.1 - 2.2e-33 115.0 0.0 8.7e-33 113.1 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 EMC93930.1 - 9.3e-35 119.9 38.1 9.3e-35 119.9 26.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC93930.1 - 2.7e-11 42.7 23.8 3.7e-11 42.2 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TauD PF02668.11 EMC93931.1 - 5.1e-49 167.2 0.3 6e-49 167.0 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.13 EMC93932.1 - 7.8e-23 80.6 0.0 1.2e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC93932.1 - 2e-05 24.3 10.8 2e-05 24.3 7.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 60KD_IMP PF02096.15 EMC93933.1 - 1.8e-30 106.1 0.1 2.6e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Fer2 PF00111.22 EMC93934.1 - 2.7e-13 49.4 0.8 2.7e-13 49.4 0.6 1.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EMC93935.1 - 2.4e-12 46.3 0.0 0.034 13.8 0.0 4.7 4 1 0 4 4 4 4 Mitochondrial carrier protein MotA_ExbB PF01618.11 EMC93935.1 - 0.091 12.3 0.1 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Sugar_tr PF00083.19 EMC93936.1 - 8.9e-21 73.9 30.0 7.1e-19 67.7 20.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Tim17 PF02466.14 EMC93937.1 - 1.3e-43 148.1 9.3 1.6e-43 147.8 6.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 EMC93937.1 - 0.024 14.5 2.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Glyco_hydro_10 PF00331.15 EMC93939.1 - 6.8e-69 232.3 0.0 8.4e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PRCC PF10253.4 EMC93939.1 - 0.11 13.1 2.2 0.2 12.3 1.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting APC8 PF04049.8 EMC93940.1 - 4e-40 136.8 0.0 9.7e-40 135.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 EMC93940.1 - 3.6e-18 64.9 20.8 5.6e-06 25.9 0.2 6.3 4 1 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 EMC93940.1 - 4.4e-18 64.0 15.8 0.00035 20.0 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC93940.1 - 3.2e-14 52.1 16.7 0.0014 19.0 0.1 8.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMC93940.1 - 6.6e-14 50.6 22.1 0.018 14.9 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC93940.1 - 9.3e-10 37.5 7.5 6.1e-05 22.5 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC93940.1 - 8.6e-08 32.0 23.1 0.24 11.3 2.2 5.9 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMC93940.1 - 9.9e-07 28.1 10.7 0.031 14.0 0.0 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC93940.1 - 1.7e-06 28.4 20.3 0.00013 22.5 0.1 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC93940.1 - 2.6e-06 27.1 10.6 4.9 7.6 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC93940.1 - 0.0031 17.3 13.4 0.017 14.9 0.2 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 EMC93940.1 - 0.035 12.8 0.1 8.9 4.9 0.0 2.8 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 EMC93940.1 - 0.042 14.1 0.0 0.042 14.1 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC93940.1 - 0.087 13.3 24.3 1.1 9.8 0.0 7.2 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC93940.1 - 0.84 9.6 6.9 2.5 8.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 EMC93941.1 - 9.2e-79 263.9 0.0 1.1e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase adh_short PF00106.20 EMC93942.1 - 2.8e-13 50.1 0.1 4.5e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC93942.1 - 3.3e-10 40.1 0.0 1e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC93942.1 - 1.5e-05 24.5 0.0 0.00013 21.5 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMC93942.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EMC93942.1 - 0.0035 17.5 0.0 0.0091 16.2 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding KR PF08659.5 EMC93942.1 - 0.0049 16.5 0.8 0.033 13.8 0.5 2.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMC93942.1 - 0.0074 15.0 0.2 0.012 14.2 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMC93942.1 - 0.012 15.6 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EMC93942.1 - 0.039 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 EMC93942.1 - 0.057 12.6 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EMC93942.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 EMC93945.1 - 1.6e-08 34.6 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC93945.1 - 5e-06 26.3 0.0 8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EMC93945.1 - 0.0014 18.7 0.1 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EMC93945.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short_C2 PF13561.1 EMC93945.1 - 0.053 13.2 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMC93945.1 - 0.064 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DNA_ligase_A_M PF01068.16 EMC93946.1 - 4.4e-22 78.4 0.0 7.6e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMC93946.1 - 6.2e-15 55.4 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus AMP-binding PF00501.23 EMC93947.1 - 7.1e-19 67.4 0.2 1.4e-18 66.4 0.2 1.4 1 1 0 1 1 1 1 AMP-binding enzyme NPCC PF08058.6 EMC93948.1 - 2.6e-21 76.0 0.1 9.6e-20 70.9 0.1 2.2 1 1 0 1 1 1 1 Nuclear pore complex component Oxidored_molyb PF00174.14 EMC93949.1 - 8e-53 178.3 0.1 1.1e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EMC93949.1 - 4.4e-26 91.0 0.1 8.4e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_3_4 PF13754.1 EMC93949.1 - 0.017 15.4 1.4 0.061 13.6 0.0 2.5 2 1 0 3 3 3 0 Bacterial Ig-like domain (group 3) NAD_binding_10 PF13460.1 EMC93950.1 - 1.8e-08 34.6 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC93950.1 - 1e-05 24.9 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EMC93950.1 - 0.0034 16.1 0.0 0.0077 14.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMC93950.1 - 0.0039 16.8 0.2 0.013 15.1 0.2 1.9 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 EMC93950.1 - 0.037 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EMC93950.1 - 0.06 12.2 0.1 0.13 11.2 0.0 1.5 1 1 1 2 2 2 0 Male sterility protein Ribonuclease_T2 PF00445.13 EMC93952.1 - 2.4e-32 112.1 0.1 3.6e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family SAM_decarbox PF01536.11 EMC93953.1 - 2.3e-89 299.3 0.0 6.3e-60 202.5 0.0 2.7 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase EHN PF06441.7 EMC93954.1 - 2.4e-27 95.0 0.1 3.1e-27 94.7 0.1 1.1 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMC93954.1 - 1.4e-05 25.0 0.2 2.8e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC93954.1 - 0.022 14.3 0.3 0.042 13.3 0.1 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 EMC93956.1 - 2.3e-06 27.5 0.2 4.1e-06 26.7 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMC93956.1 - 4.1e-06 26.8 0.2 1.7e-05 24.9 0.1 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC93956.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC93956.1 - 0.02 14.6 0.0 0.072 12.8 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein TPR_10 PF13374.1 EMC93956.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat AA_permease_2 PF13520.1 EMC93957.1 - 6.8e-55 186.3 53.8 8.7e-55 185.9 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC93957.1 - 3.7e-22 78.3 45.2 5.1e-22 77.8 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease Fork_head PF00250.13 EMC93957.1 - 0.083 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Fork head domain OspE PF02471.12 EMC93957.1 - 0.094 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Borrelia outer surface protein E Tweety PF04906.8 EMC93957.1 - 0.2 10.0 1.1 0.42 8.9 0.7 1.4 1 0 0 1 1 1 0 Tweety Metallophos PF00149.23 EMC93959.1 - 1.2e-41 142.3 0.5 1.2e-41 142.3 0.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Polyketide_cyc2 PF10604.4 EMC93961.1 - 6.8e-11 42.5 0.3 2.8e-10 40.5 0.2 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EMC93961.1 - 6.5e-07 29.4 0.1 7.7e-07 29.1 0.1 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 EMC93961.1 - 0.013 15.5 0.6 0.04 14.0 0.4 1.9 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein p450 PF00067.17 EMC93962.1 - 1.5e-30 106.1 0.0 1.9e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_3 PF13302.1 EMC93963.1 - 0.029 14.5 0.2 0.036 14.2 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCCL PF03815.14 EMC93964.1 - 4.7e-20 71.3 0.0 7.7e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.16 EMC93965.1 - 7.4e-11 41.5 0.0 2.2e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II ABC2_membrane PF01061.19 EMC93966.1 - 2.4e-81 271.8 54.6 1.7e-43 148.2 11.2 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EMC93966.1 - 6.7e-33 113.8 0.0 1e-15 58.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMC93966.1 - 3.2e-31 107.0 0.1 9.5e-27 92.6 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EMC93966.1 - 7.6e-10 38.7 0.1 2.7e-09 36.9 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 EMC93966.1 - 1.6e-06 28.0 0.0 0.0018 18.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EMC93966.1 - 7.6e-06 26.0 0.0 0.059 13.3 0.0 2.4 1 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMC93966.1 - 1.1e-05 26.2 0.0 0.0083 16.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC93966.1 - 2.1e-05 24.0 0.1 0.014 14.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EMC93966.1 - 9.1e-05 21.9 0.2 0.0046 16.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMC93966.1 - 0.00036 20.6 0.1 0.28 11.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC93966.1 - 0.00077 19.4 0.8 0.034 14.1 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EMC93966.1 - 0.00094 18.6 1.0 0.025 14.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EMC93966.1 - 0.002 17.3 0.0 0.0058 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 EMC93966.1 - 0.0021 17.6 0.5 0.8 9.3 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane_3 PF12698.2 EMC93966.1 - 0.0024 16.9 47.3 0.0061 15.6 15.8 2.9 2 1 0 3 3 3 2 ABC-2 family transporter protein AAA_19 PF13245.1 EMC93966.1 - 0.0031 17.2 0.3 1.7 8.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 EMC93966.1 - 0.0054 16.6 0.7 0.079 12.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 EMC93966.1 - 0.0094 15.1 0.0 0.17 11.0 0.0 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EMC93966.1 - 0.01 16.1 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EMC93966.1 - 0.014 15.0 0.3 2.8 7.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 EMC93966.1 - 0.028 13.8 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TBD PF12845.2 EMC93966.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 TBD domain RNA_helicase PF00910.17 EMC93966.1 - 0.042 14.0 0.0 12 6.1 0.0 3.1 3 0 0 3 3 3 0 RNA helicase PduV-EutP PF10662.4 EMC93966.1 - 0.06 12.8 0.3 2.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EMC93966.1 - 0.072 13.5 0.0 8.3 6.9 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 EMC93966.1 - 0.079 12.6 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EMC93966.1 - 0.14 12.3 0.0 22 5.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMC93966.1 - 0.14 11.5 0.0 10 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EMC93966.1 - 0.16 12.2 0.0 0.67 10.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Opi1 PF08618.5 EMC93967.1 - 3.8e-53 180.9 2.8 3.9e-31 108.4 0.3 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 Ecm33 PF12454.3 EMC93968.1 - 0.0053 16.6 2.0 0.016 15.1 1.4 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein IncA PF04156.9 EMC93968.1 - 0.0065 16.0 0.1 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 IncA protein LRR_9 PF14580.1 EMC93968.1 - 0.01 15.3 0.2 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.1 EMC93968.1 - 0.01 15.5 3.5 0.01 15.5 2.4 3.2 4 0 0 4 4 4 0 Leucine rich repeat SKG6 PF08693.5 EMC93968.1 - 0.015 14.5 0.4 0.03 13.6 0.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.11 EMC93969.1 - 9.3e-37 126.5 49.1 1.3e-35 122.7 28.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.15 EMC93969.1 - 0.5 9.6 0.0 0.5 9.6 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function DUF21 DUF617 PF04759.8 EMC93970.1 - 0.039 13.5 0.1 0.094 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF617 Ribosomal_L19 PF01245.15 EMC93971.1 - 1.3e-16 60.4 0.0 2.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Asp PF00026.18 EMC93972.1 - 2.1e-59 201.3 3.9 2.3e-59 201.1 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC93972.1 - 0.00013 22.0 3.5 0.00058 19.8 2.1 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMC93972.1 - 0.0005 19.6 0.3 0.0057 16.2 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal HIF-1a_CTAD PF08778.5 EMC93973.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain adh_short PF00106.20 EMC93974.1 - 5.3e-17 62.2 3.5 3.8e-10 39.9 2.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMC93974.1 - 2.6e-08 33.7 3.2 9.2e-07 28.6 0.9 2.2 1 1 1 2 2 2 2 KR domain Epimerase PF01370.16 EMC93974.1 - 0.00043 19.7 0.1 0.0028 17.1 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC93974.1 - 0.0017 18.4 0.7 0.0051 16.8 0.5 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EMC93974.1 - 0.0048 16.6 0.0 2 8.1 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase GATase_4 PF13230.1 EMC93976.1 - 2.3e-09 36.3 0.0 3.9e-08 32.3 0.0 2.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMC93976.1 - 6.1e-09 35.9 0.1 1.1e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMC93976.1 - 0.0014 17.4 0.3 0.002 16.8 0.2 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II CoA_trans PF01144.18 EMC93979.1 - 3.1e-96 320.7 2.3 5.1e-56 189.2 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EMC93979.1 - 0.037 13.6 0.8 0.071 12.7 0.0 1.8 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1680 PF07944.7 EMC93981.1 - 4.6e-17 61.4 0.2 2.4e-16 59.0 0.1 2.0 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) NAD_binding_10 PF13460.1 EMC93982.1 - 2.9e-12 46.9 0.0 7.2e-11 42.4 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC93982.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC93982.1 - 0.00016 20.4 0.0 0.00051 18.8 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMC93982.1 - 0.0014 17.5 0.0 0.053 12.4 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMC93982.1 - 0.039 13.8 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMC93982.1 - 0.079 11.8 0.0 0.86 8.4 0.0 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain CAP PF00188.21 EMC93983.1 - 6.3e-19 68.6 2.5 1.2e-18 67.7 1.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2576 PF10845.3 EMC93986.1 - 0.12 11.5 0.9 0.17 11.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) GST_N_3 PF13417.1 EMC93991.1 - 0.0014 18.7 0.4 0.0038 17.4 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MutS_III PF05192.13 EMC93992.1 - 0.008 15.9 0.2 0.027 14.2 0.1 1.8 1 1 0 1 1 1 1 MutS domain III MbeD_MobD PF04899.7 EMC93992.1 - 0.062 13.2 0.5 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 MbeD/MobD like PhzC-PhzF PF02567.11 EMC93992.1 - 0.08 12.1 0.3 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Glyco_hydro_17 PF00332.13 EMC93993.1 - 2.2e-07 30.2 2.5 5.6e-07 28.9 1.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 NAD_binding_10 PF13460.1 EMC93994.1 - 5e-18 65.7 0.0 5.3e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC93994.1 - 4.4e-11 42.4 0.0 6.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMC93994.1 - 1.3e-08 34.5 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC93994.1 - 4.1e-05 22.4 0.0 5.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EMC93994.1 - 0.0003 20.7 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EMC93994.1 - 0.0022 17.0 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1353 PF07087.6 EMC93994.1 - 0.048 13.1 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) ThiF PF00899.16 EMC93994.1 - 0.13 12.1 0.2 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 ThiF family IBR PF01485.16 EMC93995.1 - 8.8e-16 57.5 35.3 3.8e-09 36.2 8.2 3.5 3 0 0 3 3 3 2 IBR domain Sgf11 PF08209.6 EMC93995.1 - 0.0031 16.8 0.2 0.0031 16.8 0.1 3.6 5 0 0 5 5 5 1 Sgf11 (transcriptional regulation protein) Carboxyl_trans PF01039.17 EMC93996.1 - 2.6e-144 481.2 0.1 3.4e-144 480.8 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.19 EMC93997.1 - 1.1e-38 132.6 1.3 2.5e-38 131.5 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC93997.1 - 7.6e-31 107.0 0.0 1.9e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMC93997.1 - 1.7e-20 72.2 0.2 3.3e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC93997.1 - 1.1e-12 48.3 0.1 2.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EMC93997.1 - 1.6e-06 27.7 0.2 8.2e-06 25.4 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal BTB PF00651.26 EMC93998.1 - 8.7e-06 25.6 0.2 1.4e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain MIP PF00230.15 EMC93999.1 - 4.5e-48 163.6 15.9 5.8e-48 163.3 11.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.19 EMC94000.1 - 2.3e-108 362.6 27.8 2.7e-108 362.4 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC94000.1 - 3.8e-22 78.4 45.8 1.1e-16 60.4 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3989 PF13150.1 EMC94000.1 - 1.7 8.1 3.4 22 4.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) PHA_synth_III_E PF09712.5 EMC94001.1 - 2.4 7.5 19.0 0.028 13.8 2.0 3.3 2 1 1 3 3 3 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) P53_tetramer PF07710.6 EMC94002.1 - 0.13 11.3 0.2 0.66 9.1 0.0 2.0 2 0 0 2 2 2 0 P53 tetramerisation motif MPP6 PF10175.4 EMC94002.1 - 0.21 11.9 2.0 2.4 8.5 0.1 2.8 3 0 0 3 3 3 0 M-phase phosphoprotein 6 DUF566 PF04484.7 EMC94002.1 - 5.2 6.4 7.4 6.1 6.2 5.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Amidase PF01425.16 EMC94003.1 - 1.8e-28 99.6 0.7 3.2e-28 98.7 0.5 1.3 1 0 0 1 1 1 1 Amidase Grp1_Fun34_YaaH PF01184.14 EMC94004.1 - 1.2e-17 63.8 8.8 1.6e-17 63.4 6.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family GerA PF03323.8 EMC94004.1 - 0.2 9.7 3.7 0.33 9.0 0.5 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF3285 PF11688.3 EMC94004.1 - 1.5 8.4 6.6 6.1 6.5 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Transp_cyt_pur PF02133.10 EMC94005.1 - 4.9e-18 64.9 33.1 6.6e-18 64.4 22.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1049 PF06305.6 EMC94005.1 - 0.1 12.1 0.1 0.1 12.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DEAD PF00270.24 EMC94006.1 - 6.4e-40 136.3 0.4 1.1e-39 135.6 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC94006.1 - 1.2e-21 76.3 0.2 2.7e-11 43.1 0.1 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMC94006.1 - 2.4e-05 24.2 0.1 8.5e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Cupin_2 PF07883.6 EMC94008.1 - 1.2e-14 53.5 1.4 1.4e-14 53.2 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EMC94008.1 - 3.3e-05 23.3 0.1 4.5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EMC94008.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 EMC94008.1 - 0.00018 21.2 0.1 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMC94008.1 - 0.0012 18.1 0.1 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.9 EMC94008.1 - 0.042 13.7 1.2 0.078 12.9 0.0 1.9 1 1 1 2 2 2 0 ARD/ARD' family MannoseP_isomer PF01050.13 EMC94008.1 - 0.049 13.2 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase MFS_1 PF07690.11 EMC94009.1 - 8.1e-31 106.9 21.8 8.1e-31 106.9 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tautomerase_2 PF14552.1 EMC94010.1 - 2.1e-28 98.1 0.1 4e-28 97.2 0.0 1.4 2 0 0 2 2 2 1 Tautomerase enzyme Tautomerase PF01361.16 EMC94010.1 - 2.2e-06 27.1 0.0 0.00032 20.2 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme WD40 PF00400.27 EMC94012.1 - 2.2e-20 71.7 9.2 3.1e-05 23.6 0.1 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat CDC45 PF02724.9 EMC94012.1 - 0.78 7.6 19.0 1.1 7.1 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMC94012.1 - 1.5 6.6 27.8 2 6.2 19.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EMC94012.1 - 2.3 7.7 0.0 2.3 7.7 0.0 3.4 2 1 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 EMC94012.1 - 5.5 6.5 15.3 13 5.3 10.6 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region BTB PF00651.26 EMC94013.1 - 1.2e-10 41.3 0.0 8.7e-10 38.5 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain Acetyltransf_4 PF13420.1 EMC94014.1 - 1.4e-18 67.3 0.0 1.6e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC94014.1 - 1.9e-05 24.7 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC94014.1 - 2.7e-05 24.1 0.0 7.5e-05 22.6 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMC94014.1 - 0.0005 19.7 0.0 0.0017 18.0 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein BTB PF00651.26 EMC94015.1 - 6e-08 32.6 0.0 1.7e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain WD40 PF00400.27 EMC94016.1 - 2.6e-39 131.7 20.3 4.7e-08 32.6 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat PFU PF09070.6 EMC94016.1 - 4.1e-39 133.2 0.0 7e-39 132.4 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EMC94016.1 - 1.5e-26 92.8 0.1 1.9e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 PUL domain Nup160 PF11715.3 EMC94016.1 - 0.019 13.1 0.1 0.39 8.7 0.0 2.7 2 1 0 2 2 2 0 Nucleoporin Nup120/160 BTB PF00651.26 EMC94017.1 - 6.3e-10 39.0 0.0 8.1e-09 35.4 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain Acetyltransf_2 PF00797.12 EMC94018.1 - 6.7e-42 143.7 0.7 8e-39 133.6 0.1 2.1 2 0 0 2 2 2 2 N-acetyltransferase Peptidase_C71 PF12386.3 EMC94018.1 - 0.05 13.0 0.2 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei AMP-binding PF00501.23 EMC94019.1 - 1.3e-76 257.6 0.1 1.7e-76 257.3 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94019.1 - 4.2e-14 53.2 0.2 1e-13 51.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7TM_GPCR_Srv PF10323.4 EMC94019.1 - 0.13 11.3 0.1 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv IBR PF01485.16 EMC94020.1 - 1.1e-16 60.4 34.0 9.8e-09 34.9 2.0 4.5 4 1 0 4 4 4 3 IBR domain DGOK PF05035.7 EMC94020.1 - 0.098 11.3 0.5 0.14 10.8 0.3 1.1 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase DUF1682 PF07946.9 EMC94021.1 - 1.9e-98 329.2 0.0 2.3e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DAO PF01266.19 EMC94022.1 - 4.4e-53 180.4 0.1 5.9e-53 180.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC94022.1 - 0.0014 18.7 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC94022.1 - 0.0034 17.1 0.0 0.06 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC94022.1 - 0.032 14.1 0.0 0.09 12.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 EMC94023.1 - 9.2e-29 98.2 2.7 3.5e-06 26.6 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMC94023.1 - 0.038 13.4 0.0 16 5.1 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.6 EMC94024.1 - 2.5e-18 66.5 8.2 2.2e-15 57.0 0.5 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Tetraspannin PF00335.15 EMC94025.1 - 0.26 10.5 2.0 1.3 8.2 1.4 2.1 1 1 0 1 1 1 0 Tetraspanin family Mucin PF01456.12 EMC94025.1 - 0.35 10.6 17.3 0.71 9.6 12.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Prok-RING_2 PF14445.1 EMC94029.1 - 0.14 12.0 4.0 0.21 11.5 2.8 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 IBR PF01485.16 EMC94029.1 - 0.98 9.3 9.3 2.3 8.1 6.5 1.7 1 1 0 1 1 1 0 IBR domain C1_4 PF07975.7 EMC94029.1 - 2.5 8.1 8.6 9.8 6.2 0.1 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain DUF2387 PF09526.5 EMC94029.1 - 3 7.8 8.2 1.2 9.1 0.2 2.3 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-B_box PF00643.19 EMC94029.1 - 3 7.8 9.5 3.4 7.6 4.7 2.2 1 1 1 2 2 2 0 B-box zinc finger Zn_Tnp_IS91 PF14319.1 EMC94029.1 - 4.1 6.9 9.1 6.9 6.2 6.3 1.5 1 1 0 1 1 1 0 Transposase zinc-binding domain zf-piccolo PF05715.8 EMC94029.1 - 6.7 6.8 8.4 8.8 6.4 4.3 2.0 1 1 1 2 2 2 0 Piccolo Zn-finger Zn_Tnp_IS1595 PF12760.2 EMC94029.1 - 9.6 6.1 11.5 3e+02 1.3 7.9 2.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Metallophos PF00149.23 EMC94032.1 - 3.9e-10 39.4 6.3 6.9e-10 38.6 4.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Isochorismatase PF00857.15 EMC94033.1 - 2e-43 148.3 0.1 5.1e-43 147.0 0.0 1.6 1 1 1 2 2 2 1 Isochorismatase family DUF87 PF01935.12 EMC94033.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 SRR1 PF07985.7 EMC94034.1 - 0.00014 21.7 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 SRR1 CDC37_N PF03234.9 EMC94035.1 - 1.8e-55 188.0 1.4 1.8e-55 188.0 1.0 2.4 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EMC94035.1 - 3.4e-42 143.8 0.0 1.2e-41 142.1 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EMC94035.1 - 1.1e-25 89.3 0.2 4.5e-25 87.3 0.2 2.1 1 0 0 1 1 1 1 Cdc37 C terminal domain Adeno_E1B_55K_N PF04623.7 EMC94035.1 - 1.2 9.6 5.1 0.26 11.7 0.8 2.0 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus DUF4407 PF14362.1 EMC94035.1 - 5.1 5.9 10.4 1.3 7.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) NOB1_Zn_bind PF08772.6 EMC94036.1 - 3.4e-33 113.2 3.1 6.2e-33 112.4 2.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EMC94036.1 - 5.2e-05 23.0 1.5 5.2e-05 23.0 1.1 1.8 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 EMC94036.1 - 0.033 13.7 0.8 0.033 13.7 0.6 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.5 EMC94036.1 - 0.14 12.1 1.7 0.34 10.8 1.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.2 EMC94036.1 - 0.24 11.2 2.7 0.45 10.3 1.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon MFS_1 PF07690.11 EMC94039.1 - 1.4e-13 50.3 13.7 1.4e-13 50.3 9.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC94039.1 - 1.1e-06 27.5 4.3 1.1e-06 27.5 3.0 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter ELH PF02323.10 EMC94039.1 - 0.019 14.1 0.4 0.019 14.1 0.3 1.8 2 0 0 2 2 2 0 Egg-laying hormone precursor zf-HC2 PF13490.1 EMC94039.1 - 2.5 8.1 5.0 0.63 10.0 0.5 2.1 2 0 0 2 2 2 0 Putative zinc-finger NDK PF00334.14 EMC94040.1 - 6e-55 184.7 0.0 6.8e-55 184.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 EMC94041.1 - 8.4e-148 492.8 3.1 1.1e-147 492.4 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMC94041.1 - 3.5e-23 81.2 0.7 1.1e-22 79.6 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Vpu PF00558.14 EMC94042.1 - 0.042 13.3 0.6 0.061 12.8 0.4 1.2 1 0 0 1 1 1 0 Vpu protein Zn_peptidase PF04228.8 EMC94042.1 - 0.074 12.2 0.0 0.096 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Sugar_tr PF00083.19 EMC94049.1 - 3e-80 270.0 27.2 3.4e-60 203.9 3.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC94049.1 - 6.8e-14 51.3 34.0 7.5e-09 34.7 9.1 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF1686 PF07937.6 EMC94049.1 - 0.48 10.0 7.0 0.66 9.5 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1686) F-box-like PF12937.2 EMC94050.1 - 1.1e-05 25.0 0.1 3.5e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC94050.1 - 0.004 16.7 0.8 0.016 14.8 0.0 2.3 3 0 0 3 3 3 1 F-box domain DDOST_48kD PF03345.9 EMC94052.1 - 9.6e-164 544.9 0.0 1.1e-163 544.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DivIVA PF05103.8 EMC94053.1 - 0.84 9.6 11.3 1.7 8.7 7.8 1.5 1 0 0 1 1 1 0 DivIVA protein DUF106 PF01956.11 EMC94054.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF4227 PF14004.1 EMC94054.1 - 0.13 12.1 0.5 0.23 11.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF1204 PF06721.6 EMC94054.1 - 0.95 8.6 4.5 0.67 9.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) EF-1_beta_acid PF10587.4 EMC94054.1 - 3.2 7.9 7.1 8.8 6.5 1.0 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Asp PF00026.18 EMC94055.1 - 8.6e-61 205.9 2.2 1.5e-60 205.1 1.5 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC94055.1 - 1.6e-07 31.4 3.8 1.6e-07 31.4 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMC94055.1 - 6e-05 23.4 1.3 0.014 15.8 0.2 4.0 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EMC94055.1 - 0.0017 17.9 0.0 0.019 14.5 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EMC94055.1 - 0.025 14.3 0.1 0.36 10.6 0.0 2.7 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease ABC_membrane PF00664.18 EMC94056.1 - 5.8e-43 147.2 17.2 7.5e-43 146.9 11.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMC94056.1 - 9.5e-35 119.8 0.0 3.5e-34 118.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EMC94056.1 - 0.00025 20.3 0.0 0.00063 19.0 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC94056.1 - 0.001 19.1 0.3 0.0057 16.6 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EMC94056.1 - 0.0018 18.3 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC94056.1 - 0.0029 17.0 0.2 0.011 15.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC94056.1 - 0.0035 17.4 0.3 0.03 14.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EMC94056.1 - 0.0061 16.0 0.2 0.23 10.9 0.1 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA PF00004.24 EMC94056.1 - 0.014 15.6 0.1 0.2 11.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMC94056.1 - 0.015 14.7 0.4 0.39 10.1 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EMC94056.1 - 0.017 15.9 0.0 0.034 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC94056.1 - 0.018 14.5 0.0 0.054 13.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMC94056.1 - 0.025 14.4 0.5 0.18 11.7 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EMC94056.1 - 0.034 13.7 0.8 0.24 10.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EMC94056.1 - 0.049 12.2 0.1 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF87 PF01935.12 EMC94056.1 - 0.061 13.1 0.1 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF3987 PF13148.1 EMC94056.1 - 0.071 11.6 0.0 0.14 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Clathrin_lg_ch PF01086.12 EMC94057.1 - 7e-69 232.1 18.2 1.5e-68 231.1 12.6 1.5 1 1 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 EMC94057.1 - 0.15 11.5 0.6 0.37 10.3 0.4 1.6 1 0 0 1 1 1 0 Integrase core domain CTD_bind PF04818.8 EMC94058.1 - 3.6e-21 75.1 0.0 7.4e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4267 PF14087.1 EMC94060.1 - 3.8e-21 74.7 1.4 5.6e-21 74.2 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) ABC_cobalt PF09819.4 EMC94060.1 - 0.033 14.1 2.7 0.048 13.6 1.9 1.3 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component Lyase_1 PF00206.15 EMC94061.1 - 7.7e-25 87.7 0.0 2.4e-24 86.0 0.0 1.7 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 EMC94061.1 - 4e-16 58.7 0.0 1.5e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus AA_permease PF00324.16 EMC94062.1 - 2.9e-125 418.3 42.3 3.5e-125 418.0 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMC94062.1 - 4.2e-40 137.5 46.7 5.2e-40 137.2 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease CNH PF00780.17 EMC94063.1 - 4.7e-71 239.4 0.0 6.8e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EMC94063.1 - 3.7e-29 101.8 0.1 6.9e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EMC94063.1 - 1.1e-14 54.5 0.0 8.8e-13 48.3 0.0 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMC94063.1 - 2.5e-05 24.4 0.0 9.5e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 PH domain FMO-like PF00743.14 EMC94065.1 - 1.2e-16 60.0 0.3 1.8e-15 56.1 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMC94065.1 - 1.4e-13 51.3 0.0 4e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC94065.1 - 1.6e-05 24.8 0.1 9.1e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMC94065.1 - 3e-05 23.1 0.0 0.0067 15.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMC94065.1 - 0.0077 16.0 0.6 0.18 11.5 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC94065.1 - 0.04 13.7 0.0 0.45 10.3 0.0 2.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC94065.1 - 0.099 11.7 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family DUF1902 PF08972.6 EMC94065.1 - 0.1 12.1 0.9 0.27 10.8 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) 2-Hacid_dh_C PF02826.14 EMC94065.1 - 0.21 10.7 0.1 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EMC94066.1 - 4.8e-17 62.3 0.2 7.9e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC94066.1 - 3.8e-11 42.9 0.0 6.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC94066.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMC94066.1 - 0.0029 17.3 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMC94066.1 - 0.054 12.3 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMC94066.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mito_carr PF00153.22 EMC94067.1 - 6.2e-48 160.4 0.0 1.6e-17 62.9 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.8 EMC94067.1 - 0.13 12.6 20.5 1.6 9.2 0.3 4.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) SHS2_FTSA PF02491.15 EMC94067.1 - 1.7 8.6 4.1 5.2 7.0 0.1 3.2 3 0 0 3 3 3 0 SHS2 domain inserted in FTSA PPR_3 PF13812.1 EMC94070.1 - 0.0021 18.2 1.7 0.34 11.3 0.0 4.0 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EMC94070.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family Pyridox_ox_2 PF12900.2 EMC94071.1 - 8.7e-32 109.9 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1769 PF08588.5 EMC94072.1 - 1.4e-24 85.7 0.7 3.9e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Annexin PF00191.15 EMC94073.1 - 9.7e-71 233.6 8.7 1.6e-17 63.1 0.1 4.1 4 0 0 4 4 4 4 Annexin DUF515 PF04415.7 EMC94073.1 - 0.026 12.7 0.1 0.065 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF515) PAT1 PF09770.4 EMC94075.1 - 0.17 10.0 19.0 0.22 9.7 13.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 EMC94075.1 - 0.94 8.4 4.4 1.1 8.1 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Dsh_C PF12316.3 EMC94075.1 - 1.7 8.6 38.0 0.03 14.4 7.1 2.6 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF1777 PF08648.7 EMC94075.1 - 4.6 6.9 26.0 7.1 6.3 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Aa_trans PF01490.13 EMC94077.1 - 3.9e-96 322.0 12.3 3.9e-96 322.0 8.5 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein 60KD_IMP PF02096.15 EMC94077.1 - 0.46 10.1 5.2 0.098 12.3 0.6 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein SK_channel PF03530.9 EMC94077.1 - 4.3 7.1 8.0 4.8 7.0 0.1 3.0 3 0 0 3 3 3 0 Calcium-activated SK potassium channel M157 PF11624.3 EMC94078.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 FAD_binding_3 PF01494.14 EMC94079.1 - 1.1e-81 274.6 0.0 1.4e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMC94079.1 - 1.3e-42 145.2 0.0 2.2e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EMC94079.1 - 0.00043 18.8 0.0 0.00063 18.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EMC94079.1 - 0.0035 16.3 0.0 0.06 12.2 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 EMC94079.1 - 0.0041 15.9 0.0 0.038 12.8 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 EMC94079.1 - 0.0056 16.6 0.1 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMC94079.1 - 0.0061 15.6 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMC94079.1 - 0.017 14.0 0.1 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMC94079.1 - 0.025 14.4 0.0 0.096 12.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC94079.1 - 0.045 13.8 0.5 0.23 11.5 0.1 2.4 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC94079.1 - 0.064 12.0 0.2 0.33 9.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 EMC94079.1 - 0.091 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_33 PF10017.4 EMC94080.1 - 3.3e-32 111.0 0.4 5.8e-32 110.2 0.2 1.5 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EMC94080.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Zn_clus PF00172.13 EMC94082.1 - 3.2e-08 33.3 9.0 6.4e-08 32.3 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC94082.1 - 1.5e-05 23.9 0.0 3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydro_lipase PF04083.11 EMC94083.1 - 4.5e-20 70.7 0.1 9.7e-20 69.6 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMC94083.1 - 3.8e-15 56.0 0.7 6.2e-15 55.3 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC94083.1 - 1.6e-07 31.4 0.1 3.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMC94083.1 - 0.011 15.1 0.0 0.25 10.7 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EMC94083.1 - 0.078 12.4 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 EMC94084.1 - 4.6e-28 97.0 1.2 5.2e-28 96.8 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 EMC94084.1 - 0.15 11.7 0.4 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 PAN-like domain TRAM_LAG1_CLN8 PF03798.11 EMC94087.1 - 1.2e-34 119.6 16.3 1.2e-34 119.6 11.3 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EMC94087.1 - 2.4e-17 62.1 0.2 6.7e-17 60.7 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein DLIC PF05783.6 EMC94088.1 - 2.6e-12 46.1 6.4 7.3e-05 21.6 0.0 4.1 5 0 0 5 5 5 3 Dynein light intermediate chain (DLIC) NUDIX_2 PF13869.1 EMC94090.1 - 7.7e-80 266.6 0.0 9e-80 266.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Fungal_trans PF04082.13 EMC94093.1 - 3e-12 45.9 0.0 4.1e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94093.1 - 7.7e-11 41.7 10.4 1.2e-10 41.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMC94094.1 - 1.7e-27 96.3 0.9 2.2e-27 96.0 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC94094.1 - 2e-17 63.4 0.4 2.8e-17 62.9 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC94094.1 - 2.7e-14 53.5 0.0 3.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC94094.1 - 3.2e-12 46.4 0.0 4.3e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC94094.1 - 6.2e-08 32.8 0.1 1.2e-07 31.9 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMC94094.1 - 8.9e-05 21.5 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein DUF2493 PF10686.4 EMC94094.1 - 0.0044 16.5 1.9 9.6 5.8 0.0 3.8 2 2 2 4 4 4 2 Protein of unknown function (DUF2493) Eno-Rase_NADH_b PF12242.3 EMC94094.1 - 0.022 14.5 0.8 0.091 12.5 0.3 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.10 EMC94094.1 - 0.04 13.5 0.1 0.087 12.4 0.1 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus NmrA PF05368.8 EMC94094.1 - 0.041 13.1 0.3 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family ATP-grasp_5 PF13549.1 EMC94094.1 - 0.066 12.4 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DUF4066 PF13278.1 EMC94095.1 - 1.1e-24 86.5 0.4 1.2e-22 79.9 0.1 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EMC94095.1 - 1.2e-05 24.7 0.0 2.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family LcrG PF07216.7 EMC94096.1 - 0.064 13.2 0.2 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 LcrG protein p450 PF00067.17 EMC94098.1 - 4.4e-39 134.2 0.0 5.7e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4574 PF15141.1 EMC94098.1 - 0.23 11.2 0.5 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) Utp12 PF04003.7 EMC94099.1 - 0.17 11.8 3.7 0.62 10.0 0.1 3.0 2 1 0 2 2 2 0 Dip2/Utp12 Family Hid1 PF12722.2 EMC94101.1 - 9.2e-165 549.7 0.0 1.7e-158 529.0 0.0 2.5 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EMC94101.1 - 2.3e-59 201.2 0.0 5e-59 200.0 0.0 1.6 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Peptidase_M16 PF00675.15 EMC94102.1 - 1.3e-32 112.5 2.9 5.9e-31 107.2 1.1 3.2 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMC94102.1 - 9e-30 103.7 0.4 3.2e-18 66.0 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain BNR_2 PF13088.1 EMC94103.1 - 1.1e-06 28.2 0.0 8.1e-05 22.0 0.0 2.2 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EMC94103.1 - 0.056 13.2 13.6 0.41 10.6 0.1 4.0 4 0 0 4 4 4 0 BNR/Asp-box repeat 3HCDH_N PF02737.13 EMC94104.1 - 0.02 14.5 4.8 0.059 13.0 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3086 PF11285.3 EMC94104.1 - 0.13 11.0 7.1 0.17 10.6 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) HAUS-augmin3 PF14932.1 EMC94104.1 - 0.52 9.4 10.8 0.68 9.0 7.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.9 EMC94104.1 - 1.4 8.8 20.9 2 8.3 14.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3585 PF12130.3 EMC94104.1 - 1.8 8.4 15.5 7.2 6.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3585) MxiH PF09392.5 EMC94104.1 - 9.4 6.8 11.9 9 6.9 6.7 2.0 2 1 0 2 2 2 0 Type III secretion needle MxiH like Sugar_tr PF00083.19 EMC94105.1 - 1.5e-99 333.6 18.3 1.7e-99 333.4 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC94105.1 - 5.5e-27 94.4 28.8 9e-26 90.4 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.6 EMC94105.1 - 0.01 15.6 3.6 0.01 15.6 2.5 2.1 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Alpha-L-AF_C PF06964.7 EMC94106.1 - 1.1e-36 126.2 1.0 1.9e-36 125.5 0.7 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus FAD_binding_1 PF00667.15 EMC94107.1 - 1.5e-48 165.1 0.0 5.3e-48 163.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 EMC94107.1 - 1e-10 42.1 0.0 2.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cupin_2 PF07883.6 EMC94108.1 - 1.7e-11 43.4 0.8 1.7e-11 43.4 0.5 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EMC94108.1 - 4.1e-06 26.2 0.0 5.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Cupin GPI PF06560.6 EMC94108.1 - 0.00056 18.9 0.1 0.00083 18.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) AraC_binding PF02311.14 EMC94108.1 - 0.0019 17.9 0.2 0.0019 17.9 0.1 1.8 2 0 0 2 2 2 1 AraC-like ligand binding domain FdtA PF05523.6 EMC94108.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal JmjC PF02373.17 EMC94108.1 - 0.021 15.0 0.1 0.11 12.7 0.1 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase Pirin PF02678.11 EMC94108.1 - 3.1 7.7 5.7 0.19 11.6 0.2 1.8 2 1 0 2 2 2 0 Pirin OPT PF03169.10 EMC94110.1 - 9.3e-159 529.7 46.3 1.1e-158 529.5 32.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GST_N_2 PF13409.1 EMC94111.1 - 3e-13 49.5 0.0 9e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC94111.1 - 3.2e-10 39.7 0.0 3.7e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC94111.1 - 0.00069 20.0 0.0 0.0021 18.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC94111.1 - 0.004 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC94111.1 - 0.039 14.1 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DHHA2 PF02833.9 EMC94113.1 - 1.9e-26 92.7 0.0 3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EMC94113.1 - 6.8e-07 29.0 0.3 3.7e-06 26.6 0.2 2.1 1 1 0 1 1 1 1 DHH family SGS PF05002.10 EMC94114.1 - 1.6e-28 98.2 2.0 1.6e-28 98.2 1.4 2.0 2 0 0 2 2 2 1 SGS domain TPR_11 PF13414.1 EMC94114.1 - 7e-14 51.2 0.6 3.9e-11 42.4 0.4 2.4 2 0 0 2 2 2 2 TPR repeat CS PF04969.11 EMC94114.1 - 2.8e-13 50.2 0.0 5.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.12 EMC94114.1 - 3.3e-09 35.9 4.6 0.054 13.4 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC94114.1 - 4e-06 27.3 2.6 0.00071 20.1 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC94114.1 - 2.8e-05 23.5 1.4 0.24 11.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC94114.1 - 0.00013 22.2 0.1 0.0075 16.5 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC94114.1 - 0.00035 20.6 0.4 0.00071 19.6 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EMC94114.1 - 0.00045 20.0 4.2 0.007 16.2 0.8 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC94114.1 - 0.00073 19.5 0.0 0.0064 16.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC94114.1 - 0.015 15.9 2.6 5 8.0 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMC94114.1 - 0.047 13.5 1.3 0.1 12.4 0.5 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.3 EMC94114.1 - 0.074 11.7 0.2 0.16 10.6 0.1 1.6 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EMC94114.1 - 0.48 11.0 2.1 1.1e+02 3.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UQ_con PF00179.21 EMC94115.1 - 9e-52 174.2 0.0 1e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2778 PF10908.3 EMC94118.1 - 0.042 14.0 0.0 5 7.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) Glyco_hydro_28 PF00295.12 EMC94119.1 - 6.5e-18 64.7 5.3 9.5e-18 64.2 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EMC94119.1 - 6.8e-07 29.6 16.9 1.1e-05 25.6 11.4 2.5 1 1 0 1 1 1 1 Pectate lyase superfamily protein Gtr1_RagA PF04670.7 EMC94120.1 - 1.8e-87 292.3 0.1 2.3e-87 291.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EMC94120.1 - 5e-09 35.7 0.0 8.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EMC94120.1 - 5.8e-09 35.4 0.4 3.4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EMC94120.1 - 1.8e-07 31.6 0.0 8.2e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EMC94120.1 - 4.8e-06 26.5 0.0 9.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.8 EMC94120.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EMC94120.1 - 0.0048 17.2 0.2 0.014 15.6 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EMC94120.1 - 0.005 16.3 0.5 0.04 13.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EMC94120.1 - 0.02 14.0 0.2 0.073 12.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 EMC94120.1 - 0.031 13.4 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EMC94120.1 - 0.92 8.1 4.4 12 4.4 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Fungal_trans PF04082.13 EMC94122.1 - 1e-11 44.2 0.1 1.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94122.1 - 0.0002 21.1 10.4 0.00051 19.9 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1e PF01406.14 EMC94126.1 - 8e-111 369.9 0.1 1.2e-110 369.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EMC94126.1 - 1.4e-05 23.9 0.1 0.089 11.4 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (M) HTH_21 PF13276.1 EMC94127.1 - 0.0028 17.6 0.1 0.0072 16.3 0.0 1.8 1 1 0 1 1 1 1 HTH-like domain DUF1115 PF06544.7 EMC94127.1 - 0.0081 15.8 0.1 0.038 13.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) DUF1401 PF07180.6 EMC94128.1 - 0.12 12.1 0.1 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) Helicase_C_3 PF13625.1 EMC94129.1 - 8.4e-25 86.9 0.2 2.2e-24 85.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC94129.1 - 7.5e-16 58.4 0.7 4e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMC94129.1 - 3.8e-11 42.3 0.2 7.3e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC94129.1 - 9.2e-09 35.0 0.0 2.8e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC94129.1 - 8.7e-06 25.3 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1313 PF07011.6 EMC94129.1 - 0.053 13.1 0.1 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1313) CAF1A PF12253.3 EMC94130.1 - 1.2e-19 70.2 4.5 1.2e-19 70.2 3.1 2.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A MAP7 PF05672.6 EMC94130.1 - 0.00028 20.3 27.9 0.00057 19.3 19.4 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family MIP-T3 PF10243.4 EMC94130.1 - 0.00041 18.9 14.9 0.0007 18.1 10.3 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF3752 PF12572.3 EMC94130.1 - 0.0025 17.9 16.2 0.0058 16.7 11.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) CAF-1_p150 PF11600.3 EMC94130.1 - 0.084 12.2 42.5 0.021 14.2 23.3 2.9 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tuberculin PF12198.3 EMC94130.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Theoretical tuberculin protein Ycf1 PF05758.7 EMC94130.1 - 1 6.9 7.8 1.3 6.6 5.4 1.1 1 0 0 1 1 1 0 Ycf1 Atrophin-1 PF03154.10 EMC94130.1 - 1.4 7.0 20.8 0.018 13.2 7.5 2.1 2 0 0 2 2 2 0 Atrophin-1 family SAPS PF04499.10 EMC94130.1 - 4.6 5.7 6.8 6.8 5.1 4.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 EMC94130.1 - 7.9 4.6 18.2 11 4.0 12.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TP6A_N PF04406.9 EMC94131.1 - 2e-20 72.2 0.0 3.4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase zf-C2H2 PF00096.21 EMC94132.1 - 2.1e-10 40.3 7.9 0.00025 21.2 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC94132.1 - 4.2e-08 33.0 1.1 4.2e-08 33.0 0.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.13 EMC94132.1 - 4e-06 26.6 6.8 4e-06 26.6 4.7 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EMC94132.1 - 1.7e-05 24.7 13.8 0.0046 17.2 0.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3759 PF12585.3 EMC94133.1 - 3.8e-39 132.4 5.0 4.9e-39 132.1 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Abhydrolase_2 PF02230.11 EMC94134.1 - 6.3e-24 84.6 0.0 7.6e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMC94134.1 - 9.7e-08 31.8 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC94134.1 - 1.2e-05 25.2 0.1 2.3e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMC94134.1 - 0.0082 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EMC94134.1 - 0.02 14.3 0.1 0.12 11.7 0.0 2.0 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Pkinase PF00069.20 EMC94136.1 - 3.3e-70 236.2 0.0 4.6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC94136.1 - 3.1e-47 160.8 0.0 6.4e-47 159.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC94136.1 - 6.4e-06 25.3 0.0 6.5e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC94136.1 - 0.091 12.4 0.0 3.8 7.1 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family IF4E PF01652.13 EMC94137.1 - 1e-52 178.0 0.0 1.8e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 EMC94138.1 - 4e-36 124.6 0.0 7.7e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SEF14_adhesin PF06443.6 EMC94138.1 - 0.0074 15.9 0.0 0.023 14.3 0.0 1.8 1 0 0 1 1 1 1 SEF14-like adhesin AIG2 PF06094.7 EMC94139.1 - 6.1e-20 71.6 0.1 1.2e-19 70.6 0.0 1.5 2 0 0 2 2 2 1 AIG2-like family PQ-loop PF04193.9 EMC94140.1 - 6.9e-24 83.1 6.0 1.5e-15 56.5 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat ERM PF00769.14 EMC94141.1 - 1e-05 25.2 7.7 1.4e-05 24.7 5.3 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF1423 PF07227.6 EMC94141.1 - 0.035 12.7 4.8 0.046 12.3 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) G-gamma PF00631.17 EMC94141.1 - 0.14 11.8 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 GGL domain PLRV_ORF5 PF01690.12 EMC94141.1 - 0.31 10.1 6.6 0.43 9.6 4.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein bZIP_1 PF00170.16 EMC94141.1 - 0.54 10.2 17.8 24 4.9 12.3 2.2 1 1 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.12 EMC94141.1 - 0.82 10.0 19.2 4.3 7.7 13.3 2.0 1 1 0 1 1 1 0 bZIP Maf transcription factor Hap4_Hap_bind PF10297.4 EMC94141.1 - 2.1 8.3 5.6 4.1 7.4 3.9 1.5 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 EMC94141.1 - 4.3 7.2 16.6 0.92 9.3 8.6 1.9 1 1 1 2 2 2 0 Basic region leucine zipper Seryl_tRNA_N PF02403.17 EMC94141.1 - 5 7.1 12.4 7.8 6.5 8.6 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EMC94141.1 - 6.6 5.6 10.1 9.6 5.1 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0047 PF01894.12 EMC94142.1 - 1.9e-40 137.3 0.0 2.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 GFA PF04828.9 EMC94144.1 - 1.1 9.3 8.6 0.055 13.4 2.0 1.9 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme PhoD PF09423.5 EMC94145.1 - 2.8e-60 204.1 0.0 3.6e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PRCC PF10253.4 EMC94147.1 - 0.099 13.3 7.7 0.13 12.9 5.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DDHD PF02862.12 EMC94147.1 - 0.16 11.7 2.4 0.19 11.4 1.7 1.2 1 0 0 1 1 1 0 DDHD domain tRNA-synt_1c PF00749.16 EMC94148.1 - 4.1e-106 354.1 0.3 5.3e-106 353.8 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMC94148.1 - 2.3e-34 118.5 0.9 1.4e-33 115.9 0.6 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EMC94148.1 - 2.3e-06 28.0 0.8 6.4e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EMC94148.1 - 0.018 14.1 0.1 0.039 13.0 0.1 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain USP7_ICP0_bdg PF12436.3 EMC94149.1 - 6.9e-71 238.4 0.0 7.8e-68 228.3 0.0 2.3 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EMC94149.1 - 8e-58 195.3 0.0 1.8e-57 194.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EMC94149.1 - 3.8e-51 173.7 0.2 5.5e-51 173.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC94149.1 - 4.1e-24 85.5 0.0 6.2e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EMC94149.1 - 9e-10 38.8 0.4 3.1e-09 37.1 0.1 2.1 2 1 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 EMC94149.1 - 0.074 12.7 0.0 18 5.1 0.0 3.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like BCDHK_Adom3 PF10436.4 EMC94150.1 - 1.1e-45 155.1 0.1 1.8e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMC94150.1 - 2.2e-11 43.4 0.0 1.2e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMC94150.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fructosamin_kin PF03881.9 EMC94150.1 - 0.067 12.1 0.7 0.09 11.7 0.0 1.5 2 0 0 2 2 2 0 Fructosamine kinase P_C PF06640.6 EMC94151.1 - 0.05 13.5 0.2 0.078 12.9 0.1 1.2 1 0 0 1 1 1 0 P protein C-terminus Pmp3 PF01679.12 EMC94152.1 - 2.4e-14 52.7 1.8 2.4e-14 52.7 1.2 1.8 2 0 0 2 2 2 1 Proteolipid membrane potential modulator BTB PF00651.26 EMC94153.1 - 3.9e-08 33.2 0.0 6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EMC94153.1 - 0.056 13.5 0.4 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain PsbK PF02533.10 EMC94153.1 - 0.096 12.6 0.3 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component ATP-synt_C PF00137.16 EMC94156.1 - 0.14 12.0 0.1 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase subunit C GTP_cyclohydroI PF01227.17 EMC94157.1 - 4.6e-73 244.2 0.2 6.9e-73 243.7 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EMC94157.1 - 0.0066 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Pkinase PF00069.20 EMC94158.1 - 2.5e-69 233.3 0.0 3.7e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC94158.1 - 5.9e-35 120.5 0.0 1e-34 119.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC94158.1 - 0.0001 21.4 0.0 0.00019 20.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC94158.1 - 0.00013 21.0 0.0 0.0012 17.8 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Oest_recep PF02159.10 EMC94158.1 - 0.0054 16.8 2.1 0.014 15.5 1.5 1.7 1 0 0 1 1 1 1 Oestrogen receptor APH PF01636.18 EMC94158.1 - 0.015 14.9 0.2 0.19 11.4 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Transglut_core PF01841.14 EMC94159.1 - 1.2e-09 38.4 0.9 2.8e-09 37.1 0.6 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EMC94159.1 - 2.1e-07 30.3 0.0 4.9e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC94159.1 - 6.1e-05 22.3 0.1 6.1e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC94159.1 - 0.00014 21.3 0.5 0.00046 19.7 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain DUF3294 PF07957.6 EMC94160.1 - 0.016 14.7 0.4 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) MobC PF05713.6 EMC94160.1 - 0.093 12.7 0.7 0.64 10.0 0.6 2.2 2 1 0 2 2 2 0 Bacterial mobilisation protein (MobC) Neisseria_TspB PF05616.8 EMC94160.1 - 0.47 8.7 6.8 0.61 8.3 4.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Peptidase_M18 PF02127.10 EMC94161.1 - 2.9e-127 424.7 0.0 3.4e-127 424.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EMC94161.1 - 0.019 13.7 0.1 3.1 6.4 0.0 2.4 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Glyco_transf_21 PF13506.1 EMC94163.1 - 3.1e-15 55.9 0.3 9.3e-07 28.2 0.0 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EMC94163.1 - 6.9e-14 52.2 0.0 1.3e-13 51.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC94163.1 - 5.6e-05 22.8 0.0 0.0041 16.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 V_ATPase_I PF01496.14 EMC94164.1 - 0.057 11.2 16.2 0.076 10.8 11.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WEMBL PF05701.6 EMC94164.1 - 0.067 11.6 54.5 0.015 13.7 20.3 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light AKNA PF12443.3 EMC94164.1 - 0.098 12.6 21.7 0.47 10.4 3.9 3.6 1 1 2 3 3 3 0 AT-hook-containing transcription factor Fib_alpha PF08702.5 EMC94164.1 - 0.22 11.6 24.1 0.13 12.3 5.4 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1202 PF06717.6 EMC94164.1 - 0.24 10.6 12.2 0.63 9.2 1.9 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1202) Pox_A_type_inc PF04508.7 EMC94164.1 - 1.8 8.5 6.6 32 4.6 0.3 4.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Nop10p PF04135.7 EMC94166.1 - 9.1e-22 76.5 0.3 1.1e-21 76.2 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family His_Phos_1 PF00300.17 EMC94167.1 - 1.5e-16 60.8 0.0 2.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Abhydrolase_6 PF12697.2 EMC94167.1 - 0.053 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_transf_90 PF05686.7 EMC94169.1 - 6.5e-18 64.5 7.0 6e-15 54.8 0.1 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 OppC_N PF12911.2 EMC94169.1 - 0.52 9.7 0.0 0.52 9.7 0.0 2.5 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C tRNA-synt_1d PF00750.14 EMC94170.1 - 1.5e-83 280.5 7.0 1.3e-46 159.1 4.7 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EMC94170.1 - 1.7e-24 86.0 4.0 2.4e-24 85.6 0.4 2.7 2 1 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EMC94170.1 - 0.00062 20.2 0.0 0.0019 18.7 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain V_ATPase_I PF01496.14 EMC94170.1 - 0.11 10.3 3.0 0.16 9.7 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4404 PF14357.1 EMC94170.1 - 0.73 10.2 4.0 17 5.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF1999 PF09390.5 EMC94171.1 - 0.055 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Abhydrolase_6 PF12697.2 EMC94174.1 - 2.6e-07 30.7 2.4 6.3e-07 29.5 0.1 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94174.1 - 0.0053 16.3 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EMC94174.1 - 0.022 14.2 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_5 PF12695.2 EMC94174.1 - 0.023 14.4 0.1 0.045 13.5 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DHHA2 PF02833.9 EMC94174.1 - 0.074 13.2 0.1 0.45 10.7 0.0 2.2 3 0 0 3 3 3 0 DHHA2 domain Fungal_trans PF04082.13 EMC94176.1 - 1.7e-17 63.1 0.0 2.6e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94176.1 - 2.5e-07 30.4 11.4 5e-07 29.5 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Velvet PF11754.3 EMC94177.1 - 2.2e-06 27.4 0.0 7.2e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 Velvet factor DUF3602 PF12223.3 EMC94177.1 - 0.0037 17.6 0.1 0.0037 17.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3602) Pkinase PF00069.20 EMC94181.1 - 5.9e-65 218.9 0.0 7.1e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC94181.1 - 9.5e-35 119.9 0.0 1.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC94181.1 - 0.00012 21.9 0.0 0.021 14.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC94181.1 - 0.0077 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMC94181.1 - 0.054 12.3 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AMP-binding PF00501.23 EMC94182.1 - 1e-92 310.6 0.0 1.3e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94182.1 - 6.5e-17 62.2 0.3 2e-16 60.6 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.10 EMC94183.1 - 3.6e-12 46.5 0.0 8.4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SecM PF06558.7 EMC94184.1 - 0.093 12.3 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) Fungal_trans PF04082.13 EMC94185.1 - 2.5e-10 39.6 0.0 4.9e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94185.1 - 0.00099 18.9 5.6 0.0018 18.1 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF724 PF05266.9 EMC94185.1 - 0.29 10.7 0.0 0.46 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_12 PF13087.1 EMC94186.1 - 4.4e-36 124.1 0.0 9.5e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMC94186.1 - 4.3e-28 98.4 0.4 2e-27 96.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC94186.1 - 2.2e-08 33.7 0.0 5.2e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMC94186.1 - 4.8e-08 32.8 0.3 3.1e-06 26.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 EMC94186.1 - 0.00024 20.9 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EMC94186.1 - 0.0007 19.1 0.0 0.75 9.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EMC94186.1 - 0.0025 17.8 0.1 0.042 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.16 EMC94186.1 - 0.0069 15.7 0.2 0.017 14.4 0.1 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EMC94186.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 EMC94186.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.9 EMC94186.1 - 0.061 13.0 0.0 0.24 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-NF-X1 PF01422.12 EMC94186.1 - 0.078 12.9 4.2 0.17 11.8 2.9 1.5 1 0 0 1 1 1 0 NF-X1 type zinc finger AAA_22 PF13401.1 EMC94186.1 - 0.11 12.6 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain HeLo PF14479.1 EMC94187.1 - 1.1e-06 28.5 0.1 0.0092 15.7 0.1 3.3 3 0 0 3 3 3 2 Prion-inhibition and propagation adh_short_C2 PF13561.1 EMC94188.1 - 4.1e-29 102.0 0.1 1.7e-27 96.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC94188.1 - 5.7e-21 75.1 0.7 7.8e-21 74.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC94188.1 - 1.1e-11 44.7 0.3 1.6e-11 44.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC94188.1 - 0.0023 17.4 0.1 0.005 16.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC94188.1 - 0.11 11.2 0.1 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TPP_enzyme_C PF02775.16 EMC94189.1 - 0.051 13.1 0.2 0.093 12.3 0.1 1.5 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4595 PF15283.1 EMC94189.1 - 0.065 12.9 0.1 0.085 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold DUF4149 PF13664.1 EMC94193.1 - 1.4e-14 54.0 2.1 2.3e-14 53.2 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) MFS_1 PF07690.11 EMC94196.1 - 1.2e-37 129.4 58.3 2e-37 128.7 38.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC94196.1 - 3.2e-12 45.4 22.6 4.3e-12 45.0 15.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WTF PF03303.8 EMC94196.1 - 1.1 8.6 3.9 3.1 7.1 2.7 1.9 1 1 0 1 1 1 0 WTF protein Nup88 PF10168.4 EMC94197.1 - 0.00028 18.8 0.0 1.4 6.7 0.0 3.1 3 0 0 3 3 3 3 Nuclear pore component WD40 PF00400.27 EMC94197.1 - 0.025 14.4 0.5 22 5.1 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Nup54 PF13874.1 EMC94197.1 - 0.19 11.4 4.3 2.7 7.6 0.1 3.0 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Spectrin PF00435.16 EMC94197.1 - 0.23 11.7 0.1 0.23 11.7 0.1 3.2 4 0 0 4 4 4 0 Spectrin repeat Glypican PF01153.14 EMC94197.1 - 0.27 9.8 1.1 0.41 9.1 0.7 1.2 1 0 0 1 1 1 0 Glypican RRM_1 PF00076.17 EMC94198.1 - 9.2e-17 60.4 0.0 1.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC94198.1 - 5.3e-12 45.5 0.0 1.3e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC94198.1 - 1.9e-08 34.0 0.0 2.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACPS PF01648.15 EMC94199.1 - 2e-09 37.2 0.0 7.2e-08 32.2 0.0 3.2 3 1 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 EMC94200.1 - 2e-55 187.3 0.0 5.2e-46 156.6 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EMC94200.1 - 4.1e-10 39.4 0.0 1.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EMC94200.1 - 4.1e-05 23.1 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EMC94200.1 - 0.0022 17.4 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EMC94200.1 - 0.0029 16.9 0.0 0.016 14.4 0.0 2.0 1 1 1 2 2 2 1 Putative amidotransferase Peptidase_S51 PF03575.12 EMC94200.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 PAN_4 PF14295.1 EMC94201.1 - 0.0077 15.9 1.1 0.58 9.9 0.1 2.7 2 0 0 2 2 2 2 PAN domain RTC PF01137.16 EMC94203.1 - 2.5e-39 134.4 0.0 8.2e-39 132.7 0.0 1.7 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase PEP_mutase PF13714.1 EMC94204.1 - 2.9e-54 183.7 0.6 3.4e-54 183.5 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase SSF PF00474.12 EMC94205.1 - 2.9e-21 75.5 28.1 4.4e-21 74.9 19.5 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Oxidored_FMN PF00724.15 EMC94206.1 - 9.2e-96 320.7 0.0 1.1e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2OG-FeII_Oxy PF03171.15 EMC94208.1 - 5.2e-11 42.7 0.0 9.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMC94208.1 - 4.6e-07 30.3 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal eIF-5a PF01287.15 EMC94209.1 - 1.4e-07 31.3 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold CNH PF00780.17 EMC94211.1 - 1.5e-69 234.4 0.0 3.6e-69 233.2 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EMC94211.1 - 2.5e-42 144.0 0.0 6.4e-42 142.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EMC94211.1 - 1.3e-38 132.6 0.0 2.3e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EMC94211.1 - 4.7e-13 48.6 0.0 1.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 EMC94211.1 - 0.047 13.9 0.0 1.1 9.5 0.0 3.0 2 1 0 2 2 2 0 PH domain ATP-synt_C PF00137.16 EMC94212.1 - 5.4e-25 87.0 31.6 4.3e-16 58.5 5.3 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Ank_2 PF12796.2 EMC94213.1 - 2.2e-12 47.1 1.0 0.00017 21.8 0.3 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC94213.1 - 2.3e-08 33.4 3.0 0.06 13.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EMC94213.1 - 5e-06 26.5 4.3 0.0035 17.5 0.2 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC94213.1 - 5.1e-05 23.1 5.1 0.55 10.6 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeat APC_crr PF05923.7 EMC94213.1 - 0.0015 18.0 0.1 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 APC cysteine-rich region Ank_4 PF13637.1 EMC94213.1 - 0.0044 17.4 8.8 3.3 8.3 0.2 5.5 5 2 2 7 7 7 2 Ankyrin repeats (many copies) PhoD PF09423.5 EMC94214.1 - 7e-150 499.5 11.1 8.2e-150 499.3 7.7 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase NmrA PF05368.8 EMC94216.1 - 5.7e-16 58.4 0.0 8.8e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC94216.1 - 1.3e-14 54.6 0.1 3e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC94216.1 - 1.5e-05 24.5 0.0 2.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EMC94216.1 - 0.00056 19.8 0.1 0.00096 19.0 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMC94216.1 - 0.00061 20.0 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EMC94216.1 - 0.0016 17.3 0.1 0.0038 16.1 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EMC94216.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CoA_binding PF02629.14 EMC94216.1 - 0.024 15.1 0.2 0.052 14.0 0.2 1.5 1 0 0 1 1 1 0 CoA binding domain F420_oxidored PF03807.12 EMC94216.1 - 0.037 14.4 0.1 0.073 13.5 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EMC94216.1 - 0.047 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 EMC94216.1 - 0.16 11.8 0.2 0.28 11.0 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase NUDIX PF00293.23 EMC94217.1 - 9.4e-15 54.4 1.4 4.3e-13 49.0 0.0 2.7 1 1 2 3 3 3 3 NUDIX domain Kelch_3 PF13415.1 EMC94219.1 - 0.072 13.2 1.9 7.9 6.7 0.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain SNAP PF14938.1 EMC94220.1 - 0.025 13.7 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP OmdA PF13376.1 EMC94220.1 - 0.031 13.9 0.3 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3362 PF11842.3 EMC94220.1 - 0.068 13.0 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) Ribosomal_60s PF00428.14 EMC94221.1 - 6.5 7.2 9.6 9.2 6.7 6.7 1.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein Prenyltrans_2 PF13249.1 EMC94222.1 - 7.9e-35 119.6 3.2 8e-16 58.4 0.0 5.9 3 2 4 7 7 7 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC94222.1 - 6.9e-32 109.7 0.0 2.9e-13 49.7 0.3 6.3 4 2 2 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 EMC94222.1 - 1.1e-22 79.2 17.3 2.3e-08 33.4 0.5 6.2 6 2 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat A2M_comp PF07678.9 EMC94222.1 - 0.00016 20.9 0.1 0.012 14.8 0.0 3.2 2 1 1 3 3 3 1 A-macroglobulin complement component Pec_lyase PF09492.5 EMC94222.1 - 0.014 14.6 2.2 11 5.0 0.0 4.0 4 1 1 5 5 5 0 Pectic acid lyase zf-RanBP PF00641.13 EMC94223.1 - 2.8e-19 67.9 11.0 5.7e-11 41.3 0.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EMC94223.1 - 1.5e-07 30.9 0.0 5.8e-06 25.8 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC94223.1 - 2.6e-05 24.1 0.0 7.1e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EMC94223.1 - 0.00039 20.7 0.0 0.00066 19.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 EMC94223.1 - 2.2 8.1 8.9 1.4 8.8 1.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon Rad9_Rad53_bind PF08605.5 EMC94224.1 - 6.6e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EMC94224.1 - 0.006 16.7 0.0 0.03 14.4 0.0 2.2 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribonucleas_3_3 PF14622.1 EMC94225.1 - 4e-27 94.6 0.0 1.4e-26 92.9 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMC94225.1 - 1.3e-06 28.8 0.0 2.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain KAT11 PF08214.6 EMC94226.1 - 4e-69 233.3 0.0 8.1e-69 232.3 0.0 1.5 2 0 0 2 2 2 1 Histone acetylation protein NmrA PF05368.8 EMC94227.1 - 6e-64 215.4 0.0 7.4e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC94227.1 - 2.7e-06 27.5 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding LamB_YcsF PF03746.11 EMC94227.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 LamB/YcsF family NAP PF00956.13 EMC94229.1 - 1.2e-42 145.7 0.5 1.2e-42 145.7 0.3 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 EMC94229.1 - 0.24 11.5 10.7 0.14 12.3 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EMC94229.1 - 1.3 8.5 8.6 5.3 6.5 2.9 2.3 2 0 0 2 2 2 0 Nucleoplasmin YL1 PF05764.8 EMC94229.1 - 6.1 6.3 8.1 10 5.6 5.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein PSI PF01437.20 EMC94230.1 - 1.2e-06 28.5 7.6 2.3e-06 27.6 5.3 1.5 1 0 0 1 1 1 1 Plexin repeat EMP24_GP25L PF01105.19 EMC94233.1 - 3.7e-47 160.3 0.0 4.3e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2606 PF10794.4 EMC94233.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Glycogen_syn PF05693.8 EMC94234.1 - 0 1109.1 0.0 0 1108.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EMC94234.1 - 1e-05 25.0 0.0 0.019 14.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMC94234.1 - 0.00021 21.5 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EMC94234.1 - 0.011 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Transposase_22 PF02994.9 EMC94237.1 - 0.081 11.4 3.8 0.1 11.1 2.6 1.2 1 0 0 1 1 1 0 L1 transposable element Herpes_LMP1 PF05297.6 EMC94237.1 - 0.87 8.4 3.8 0.95 8.3 2.7 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SRP-alpha_N PF04086.8 EMC94237.1 - 2.4 7.4 5.3 3.2 7.0 3.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.5 EMC94237.1 - 9.3 4.5 8.5 9.6 4.4 5.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPC22 PF04573.7 EMC94239.1 - 1.3e-35 122.1 0.4 8e-25 87.0 0.1 2.1 2 0 0 2 2 2 2 Signal peptidase subunit EPL1 PF10513.4 EMC94240.1 - 0.19 11.9 3.3 2.7 8.2 0.6 2.1 1 1 1 2 2 2 0 Enhancer of polycomb-like RIC3 PF15361.1 EMC94240.1 - 5.7 7.1 5.8 2.6 8.2 1.0 2.2 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Methyltransf_23 PF13489.1 EMC94244.1 - 5e-14 52.3 0.0 6.6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC94244.1 - 1.8e-06 28.3 0.0 2.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC94244.1 - 1.1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC94244.1 - 0.00058 20.4 0.0 0.00094 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC94244.1 - 0.00096 18.3 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMC94244.1 - 0.0013 19.2 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMC94244.1 - 0.065 11.9 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DEAD PF00270.24 EMC94246.1 - 4.8e-40 136.8 0.2 8.3e-40 136.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC94246.1 - 5.3e-28 96.6 0.1 1.1e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EMC94246.1 - 0.0017 18.0 0.3 0.0041 16.8 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMC94246.1 - 0.0098 15.4 0.3 0.024 14.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EMC94246.1 - 0.03 14.0 0.2 0.11 12.2 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.10 EMC94246.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EMC94246.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.1 EMC94246.1 - 0.12 11.9 0.2 0.25 10.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMC94246.1 - 0.18 11.9 1.0 0.84 9.7 0.7 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 EMC94247.1 - 1.9e-69 233.1 1.7 3.2e-69 232.3 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EMC94247.1 - 1.1e-14 53.6 0.8 2.3e-14 52.6 0.6 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EMC94247.1 - 6.5e-08 32.5 1.5 8.5e-06 25.7 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC94247.1 - 1.4e-07 31.4 2.7 6.7e-06 26.0 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC94247.1 - 0.0022 18.0 0.2 0.13 12.4 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EMC94247.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-DBF PF07535.7 EMC94247.1 - 1.7 8.4 5.2 0.86 9.3 0.1 2.9 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.21 EMC94247.1 - 2.1 8.8 4.9 12 6.4 0.4 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Voldacs PF03517.8 EMC94249.1 - 4.1e-19 68.7 2.6 1.1e-18 67.3 1.8 1.7 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Epimerase PF01370.16 EMC94250.1 - 1.6e-10 40.8 0.1 1.2e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC94250.1 - 2.6e-09 37.3 0.0 4.6e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMC94250.1 - 1e-06 27.6 0.1 5.6e-06 25.2 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMC94250.1 - 9.7e-05 21.7 0.1 0.00031 20.0 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EMC94250.1 - 0.029 13.2 0.0 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EMC94250.1 - 0.047 12.5 0.4 0.13 11.0 0.0 1.9 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EMC94250.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Syntaxin-6_N PF09177.6 EMC94252.1 - 6.9e-21 74.4 1.0 1.8e-20 73.1 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EMC94252.1 - 3.6e-12 45.7 3.6 3.6e-12 45.7 2.5 2.8 3 0 0 3 3 3 1 SNARE domain DUF4047 PF13256.1 EMC94252.1 - 0.0065 16.4 0.8 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4047) Laminin_II PF06009.7 EMC94252.1 - 0.0066 16.2 1.8 0.31 10.7 0.5 2.3 2 0 0 2 2 2 1 Laminin Domain II COG2 PF06148.6 EMC94252.1 - 0.012 15.4 2.8 0.024 14.4 0.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 EMC94252.1 - 0.017 14.3 2.1 0.017 14.2 0.5 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Med4 PF10018.4 EMC94252.1 - 0.048 13.0 0.7 0.085 12.2 0.5 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 PilJ PF13675.1 EMC94252.1 - 0.098 12.9 6.6 0.12 12.7 1.6 2.5 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1515 PF07439.6 EMC94252.1 - 0.17 11.6 3.6 15 5.4 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DUF1664 PF07889.7 EMC94252.1 - 0.19 11.5 5.3 4.1 7.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Uds1 PF15456.1 EMC94252.1 - 0.19 11.7 4.2 0.16 11.9 1.4 2.0 2 1 0 2 2 2 0 Up-regulated During Septation FlaC_arch PF05377.6 EMC94252.1 - 0.24 11.3 1.6 34 4.4 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DegS PF05384.6 EMC94252.1 - 0.24 10.6 7.2 1.2 8.3 0.3 3.0 3 0 0 3 3 3 0 Sensor protein DegS Baculo_PEP_C PF04513.7 EMC94252.1 - 0.36 10.6 4.1 6 6.6 1.3 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EMC94252.1 - 0.41 10.1 1.9 0.42 10.1 0.1 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4407 PF14362.1 EMC94252.1 - 0.83 8.5 7.0 0.07 12.0 0.6 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) HisKA_3 PF07730.8 EMC94252.1 - 0.84 10.0 7.6 1.4 9.2 0.1 3.2 2 1 1 3 3 3 0 Histidine kinase MtrG PF04210.8 EMC94252.1 - 1.4 8.6 4.1 0.89 9.2 0.4 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Methyltransf_32 PF13679.1 EMC94253.1 - 3.8e-23 81.7 0.0 6.2e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain IBR PF01485.16 EMC94255.1 - 1.7e-07 30.9 10.2 1.7e-07 30.9 7.0 2.9 2 1 1 3 3 3 2 IBR domain Nop10p PF04135.7 EMC94255.1 - 0.1 12.3 2.4 0.25 11.1 0.9 2.3 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family ACT_7 PF13840.1 EMC94256.1 - 6.2e-22 76.9 0.0 1.6e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 ACT domain IPP-2 PF04979.9 EMC94257.1 - 2.5e-11 43.9 14.1 1.6e-08 34.8 1.2 2.5 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) SOG2 PF10428.4 EMC94257.1 - 2.8 6.4 5.5 3.1 6.3 3.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAD_binding_4 PF01565.18 EMC94258.1 - 3.4e-13 49.2 6.2 4.6e-12 45.5 4.3 2.4 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMC94258.1 - 3.7e-07 29.9 0.1 9.1e-07 28.6 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Ofd1_CTDD PF10637.4 EMC94259.1 - 2e-88 295.9 0.7 2.4e-79 266.2 1.4 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EMC94259.1 - 1.7e-13 50.9 0.1 4.2e-13 49.6 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MARVEL PF01284.18 EMC94260.1 - 3.9e-05 23.4 6.3 3.9e-05 23.4 4.4 2.2 2 0 0 2 2 2 1 Membrane-associating domain 5TM-5TMR_LYT PF07694.7 EMC94260.1 - 0.046 13.0 6.7 0.068 12.5 4.6 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF1129 PF06570.6 EMC94260.1 - 1.8 7.8 4.3 1.2 8.3 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Voltage_CLC PF00654.15 EMC94260.1 - 2.6 6.9 9.7 2.3 7.1 5.3 1.8 1 1 1 2 2 2 0 Voltage gated chloride channel RabGAP-TBC PF00566.13 EMC94261.1 - 3e-48 164.1 0.0 4.1e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EMC94261.1 - 0.0069 16.4 0.1 0.049 13.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair DUF1688 PF07958.6 EMC94263.1 - 2.1e-181 603.0 0.0 2.4e-181 602.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Sdh_cyt PF01127.17 EMC94264.1 - 4.9e-24 84.4 5.9 6.3e-24 84.1 4.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Acetyltransf_1 PF00583.19 EMC94265.1 - 1.1e-12 47.7 0.1 2.5e-12 46.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC94265.1 - 3.1e-10 40.0 0.0 2.1e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC94265.1 - 1.3e-08 34.7 0.0 2.5e-08 33.8 0.0 1.5 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC94265.1 - 2.3e-07 30.9 0.1 3e-06 27.3 0.0 2.2 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC94265.1 - 0.0029 17.4 0.0 0.0064 16.3 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EMC94265.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein ADH_N_assoc PF13823.1 EMC94265.1 - 0.54 9.9 3.5 0.25 11.0 0.5 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated zf-CHY PF05495.7 EMC94266.1 - 5.6e-14 52.0 20.8 7.1e-14 51.7 14.4 1.1 1 0 0 1 1 1 1 CHY zinc finger DRP PF06044.7 EMC94266.1 - 0.18 10.7 2.1 0.2 10.6 1.4 1.3 1 0 0 1 1 1 0 Dam-replacing family Tmemb_55A PF09788.4 EMC94266.1 - 0.48 9.5 7.7 0.54 9.3 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A DNA_RNApol_7kD PF03604.8 EMC94266.1 - 0.54 9.7 0.1 0.54 9.7 0.1 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.2 EMC94266.1 - 1.2 9.0 13.1 21 5.0 0.1 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 EMC94266.1 - 2.7 7.6 15.8 4.1 7.0 10.9 1.3 1 0 0 1 1 1 0 Cytochrome c7 zf-RING_3 PF14369.1 EMC94266.1 - 2.8 8.0 11.8 1.6 8.7 4.4 2.7 1 1 1 2 2 2 0 zinc-finger Evr1_Alr PF04777.8 EMC94266.1 - 7.2 6.5 12.7 4.3e+02 0.8 8.8 2.8 1 1 0 1 1 1 0 Erv1 / Alr family C1_4 PF07975.7 EMC94266.1 - 9.3 6.3 16.7 9.4 6.3 5.2 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain Exo_endo_phos PF03372.18 EMC94267.1 - 2.1e-23 83.5 0.7 4.2e-23 82.5 0.1 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EMC94267.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EMC94267.1 - 0.078 12.8 0.7 0.34 10.8 0.2 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat GFA PF04828.9 EMC94268.1 - 5.7e-11 42.2 2.3 5.7e-11 42.2 1.6 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HDA2-3 PF11496.3 EMC94269.1 - 9.5e-16 57.4 0.0 1.6e-14 53.4 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Latarcin PF10279.4 EMC94269.1 - 0.061 13.5 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Latarcin precursor Filament PF00038.16 EMC94269.1 - 0.41 10.0 18.8 0.81 9.0 12.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF1546 PF07571.8 EMC94271.1 - 1.5e-32 111.5 0.0 4.2e-32 110.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EMC94271.1 - 1.1e-24 86.1 0.2 2.5e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EMC94271.1 - 1.6e-06 28.1 0.3 8.9e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC94271.1 - 0.00028 20.8 0.1 0.00085 19.3 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC94271.1 - 0.0067 16.1 0.2 0.025 14.2 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated CENP-S PF15630.1 EMC94271.1 - 0.009 16.1 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EMC94271.1 - 0.011 15.4 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CAS_CSE1 PF03378.10 EMC94271.1 - 0.15 10.3 0.3 0.47 8.6 0.0 1.8 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus POT1 PF02765.12 EMC94274.1 - 2e-07 30.9 0.0 3.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 PALP PF00291.20 EMC94275.1 - 1.1e-60 205.5 0.1 1.3e-60 205.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.2 EMC94276.1 - 1.6e-81 273.5 0.0 4.2e-81 272.2 0.0 1.7 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EMC94276.1 - 4e-09 36.6 10.0 0.00015 22.0 1.7 5.0 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EMC94276.1 - 8.9e-07 28.4 4.2 0.12 12.5 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat DUF1546 PF07571.8 EMC94276.1 - 0.021 14.9 1.2 0.52 10.4 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) CLASP_N PF12348.3 EMC94276.1 - 0.039 13.3 0.9 0.6 9.4 0.0 2.5 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.1 EMC94276.1 - 0.21 12.0 16.6 1.7 9.2 0.2 6.4 4 1 3 7 7 7 0 HEAT-like repeat Scramblase PF03803.10 EMC94280.1 - 1.4e-52 177.9 0.0 1.1e-26 93.2 0.0 3.0 3 0 0 3 3 3 3 Scramblase Fork_head_N PF08430.7 EMC94280.1 - 4.1 7.7 8.3 7.2 7.0 4.4 2.3 2 0 0 2 2 2 0 Forkhead N-terminal region tRNA_int_endo PF01974.12 EMC94281.1 - 8.8e-21 73.5 0.1 1.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EMC94281.1 - 2.3e-06 27.0 0.0 0.0003 20.2 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain TPR_11 PF13414.1 EMC94282.1 - 4.6e-11 42.1 0.3 5.9e-09 35.4 0.0 2.5 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 EMC94282.1 - 3.1e-08 33.2 0.3 1e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain TPR_1 PF00515.23 EMC94282.1 - 2.9e-05 23.4 0.3 1 9.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC94282.1 - 3e-05 23.6 4.5 0.92 9.5 0.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC94282.1 - 0.0056 16.5 0.4 1.7 8.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 EMC94282.1 - 0.008 15.8 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_cc PF11790.3 EMC94285.1 - 7.6e-31 107.3 1.0 9.5e-31 107.0 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SLT PF01464.15 EMC94288.1 - 2.8e-05 23.6 0.3 0.012 15.0 0.0 2.2 2 0 0 2 2 2 2 Transglycosylase SLT domain WD40 PF00400.27 EMC94289.1 - 2.3e-46 154.0 30.2 1.2e-11 43.9 0.0 12.0 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.7 EMC94289.1 - 1.4e-21 76.4 0.1 2.1e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EMC94289.1 - 2.9e-06 27.1 0.1 0.14 11.8 0.0 5.5 5 1 2 7 7 7 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMC94289.1 - 0.055 11.7 0.1 0.47 8.7 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain IKI3 PF04762.7 EMC94289.1 - 0.065 11.0 0.2 2.2 5.9 0.0 2.6 2 1 0 2 2 2 0 IKI3 family PQQ_3 PF13570.1 EMC94289.1 - 0.81 10.0 10.1 4.4 7.7 0.1 5.5 4 1 0 4 4 4 0 PQQ-like domain Septin PF00735.13 EMC94290.1 - 1.1e-114 382.2 0.1 1.5e-114 381.7 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMC94290.1 - 1.6e-07 31.2 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC94290.1 - 1.2e-05 24.5 0.0 3.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMC94290.1 - 3e-05 23.5 0.5 0.00015 21.3 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMC94290.1 - 0.0014 18.8 0.2 0.0049 17.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EMC94290.1 - 0.0028 17.2 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EMC94290.1 - 0.0032 17.9 0.0 0.011 16.1 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EMC94290.1 - 0.0047 16.0 0.0 0.009 15.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 EMC94290.1 - 0.0078 15.7 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EMC94290.1 - 0.0082 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EMC94290.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.1 EMC94290.1 - 0.02 14.8 1.0 0.26 11.2 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EMC94290.1 - 0.023 13.5 0.4 0.075 11.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EMC94290.1 - 0.04 13.6 0.1 0.04 13.6 0.1 1.9 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EMC94290.1 - 0.04 14.2 0.1 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Ras PF00071.17 EMC94290.1 - 0.047 13.0 0.4 0.14 11.5 0.3 1.8 1 1 0 1 1 1 0 Ras family PduV-EutP PF10662.4 EMC94290.1 - 0.054 12.9 0.2 2.5 7.5 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EMC94290.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 EMC94290.1 - 0.071 12.0 0.1 0.083 11.8 0.1 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Sigma54_activat PF00158.21 EMC94290.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.18 EMC94290.1 - 0.092 12.5 6.7 0.91 9.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EMC94290.1 - 0.14 11.7 0.7 9.5 5.6 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Atg14 PF10186.4 EMC94290.1 - 0.44 9.4 5.9 0.74 8.7 4.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 EMC94291.1 - 5.9e-40 133.7 9.9 2.3e-08 33.6 0.1 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMC94291.1 - 7.7e-05 22.4 0.0 0.35 10.6 0.0 3.1 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EMC94291.1 - 0.00013 21.5 2.9 0.00013 21.5 2.0 1.7 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EMC94291.1 - 0.0019 18.3 12.0 0.022 15.0 0.5 4.8 4 1 1 5 5 5 1 PQQ-like domain PQQ PF01011.16 EMC94291.1 - 0.034 13.6 0.1 0.84 9.2 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Aa_trans PF01490.13 EMC94292.1 - 2.3e-21 75.7 38.0 2.8e-21 75.4 26.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBV_3C PF03620.8 EMC94292.1 - 0.078 12.8 0.8 0.59 10.0 0.1 2.8 2 0 0 2 2 2 0 IBV 3C protein MFS_1 PF07690.11 EMC94293.1 - 3.7e-34 117.9 29.1 5.1e-34 117.5 20.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_7 PF00840.15 EMC94293.1 - 0.15 10.4 0.0 0.29 9.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 F-box-like PF12937.2 EMC94294.1 - 2.2e-09 36.9 0.1 7.2e-09 35.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC94294.1 - 0.001 18.6 4.8 0.0057 16.2 0.3 3.8 4 1 0 4 4 4 1 F-box domain Methyltransf_11 PF08241.7 EMC94295.1 - 5.5e-11 42.8 0.0 8.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC94295.1 - 1.1e-05 25.0 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC94295.1 - 1.4e-05 25.5 0.0 2.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC94295.1 - 0.00044 20.5 0.0 0.00086 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC94295.1 - 0.0011 18.9 0.0 0.0027 17.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC94295.1 - 0.002 18.5 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 EMC94296.1 - 7.2e-33 113.7 32.7 7.2e-33 113.7 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.19 EMC94299.1 - 2.1e-19 70.0 31.3 2.1e-19 70.0 21.7 1.6 1 1 1 2 2 2 1 Fatty acid desaturase CPSase_L_D2 PF02786.12 EMC94303.1 - 7.1e-74 247.6 0.0 1.1e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EMC94303.1 - 1.8e-37 127.5 0.0 1e-36 125.1 0.0 2.2 1 1 1 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EMC94303.1 - 3.2e-33 114.1 0.0 6.4e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EMC94303.1 - 6.5e-19 68.3 0.0 4.1e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC94303.1 - 3.6e-15 55.5 0.0 5.7e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EMC94303.1 - 8e-11 41.4 1.4 2.1e-10 40.0 1.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EMC94303.1 - 1.2e-09 37.8 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMC94303.1 - 5.7e-08 32.3 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMC94303.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EMC94303.1 - 0.00016 21.1 0.0 0.0007 19.1 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EMC94303.1 - 0.00088 18.8 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like Toxin_59 PF15537.1 EMC94303.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 Putative toxin 59 Peptidase_M24 PF00557.19 EMC94305.1 - 2.8e-45 154.4 0.1 3.5e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EMC94305.1 - 0.0046 16.7 7.0 0.0046 16.7 4.9 2.5 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.9 EMC94306.1 - 4.5e-54 181.9 10.9 5.1e-54 181.8 7.6 1.0 1 0 0 1 1 1 1 Cornichon protein NMT PF01233.14 EMC94307.1 - 9.5e-70 233.4 0.0 1.7e-69 232.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EMC94307.1 - 4.7e-67 225.0 0.0 6.3e-67 224.6 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EMC94307.1 - 5.6e-05 22.9 0.0 0.00017 21.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Nop53 PF07767.6 EMC94307.1 - 0.018 14.0 7.4 0.028 13.4 5.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 EMC94307.1 - 0.21 9.4 9.7 0.31 8.9 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF572 PF04502.8 EMC94307.1 - 0.3 10.2 5.0 0.51 9.5 3.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) NST1 PF13945.1 EMC94307.1 - 0.47 10.5 5.4 0.081 12.9 1.1 1.7 2 0 0 2 2 2 0 Salt tolerance down-regulator AMP-binding PF00501.23 EMC94308.1 - 1.5e-99 333.2 0.0 1.9e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94308.1 - 3.8e-10 40.5 0.1 8.9e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1286 PF06939.6 EMC94308.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1286) Form_Nir_trans PF01226.12 EMC94309.1 - 1.8e-44 151.5 10.2 2.3e-44 151.1 7.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Ras PF00071.17 EMC94310.1 - 1.4e-59 200.1 0.2 1.6e-59 199.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC94310.1 - 2.4e-19 70.0 0.1 4.5e-19 69.1 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC94310.1 - 1.8e-15 56.5 0.0 2.3e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC94310.1 - 1e-07 31.5 0.0 1.9e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC94310.1 - 1.1e-06 27.9 0.0 1.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC94310.1 - 5e-06 26.4 0.0 1.3e-05 25.1 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC94310.1 - 0.016 15.3 0.1 0.75 9.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EMC94310.1 - 0.027 13.6 0.2 0.13 11.4 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EMC94310.1 - 0.059 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMC94310.1 - 0.06 13.3 0.3 0.13 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EMC94310.1 - 0.097 11.9 0.1 0.98 8.6 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B Syja_N PF02383.13 EMC94311.1 - 2.7e-91 305.6 0.3 3.5e-91 305.3 0.2 1.1 1 0 0 1 1 1 1 SacI homology domain Metallophos PF00149.23 EMC94312.1 - 2.9e-08 33.3 0.1 8.1e-08 31.8 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC94312.1 - 4.3e-07 29.8 0.1 1.1e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FAD_binding_3 PF01494.14 EMC94313.1 - 3.1e-41 141.6 0.0 4.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC94313.1 - 5.5e-05 22.2 0.0 0.028 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMC94313.1 - 0.0005 19.1 0.2 0.0012 17.8 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMC94313.1 - 0.0005 20.0 0.0 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC94313.1 - 0.00071 19.9 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC94313.1 - 0.00079 19.2 0.2 0.0018 18.0 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC94313.1 - 0.0084 16.0 0.0 0.041 13.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EMC94313.1 - 0.016 13.4 0.2 0.45 8.6 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 EMC94313.1 - 0.05 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 EMC94313.1 - 0.11 11.4 0.2 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EMC94313.1 - 0.13 10.6 0.1 0.29 9.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein SMC_N PF02463.14 EMC94314.1 - 2.8e-26 92.1 0.2 4.2e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMC94314.1 - 1.4e-17 64.7 14.2 1.4e-17 64.7 9.9 4.8 2 2 0 2 2 1 1 AAA domain AAA_15 PF13175.1 EMC94314.1 - 3.7e-06 26.2 0.0 0.00077 18.6 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EMC94314.1 - 1.2e-05 25.4 0.0 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMC94314.1 - 4.3e-05 22.9 0.0 9e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMC94314.1 - 0.0083 15.5 0.1 0.049 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMC94314.1 - 0.052 13.7 1.5 0.53 10.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 EMC94314.1 - 0.077 12.7 0.0 0.41 10.4 0.0 2.3 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EMC94314.1 - 0.32 11.8 0.0 0.32 11.8 0.0 4.1 3 2 1 5 5 5 0 AAA domain DASH_Dad3 PF08656.5 EMC94314.1 - 0.66 9.7 6.1 32 4.3 0.0 4.3 3 1 1 4 4 4 0 DASH complex subunit Dad3 AAA_22 PF13401.1 EMC94314.1 - 0.69 10.0 0.0 0.69 10.0 0.0 4.0 3 1 1 4 4 4 0 AAA domain Pox_A_type_inc PF04508.7 EMC94314.1 - 9.8 6.2 9.3 38 4.4 0.7 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat POP1 PF06978.6 EMC94315.1 - 1.5e-61 207.2 13.3 3.9e-61 205.9 9.2 1.7 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EMC94315.1 - 1e-31 108.6 1.8 2.9e-31 107.1 1.2 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain PLRV_ORF5 PF01690.12 EMC94315.1 - 2.6 7.0 14.2 0.36 9.9 6.9 1.7 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein ARPC4 PF05856.7 EMC94316.1 - 5.2e-76 253.7 1.9 5.8e-76 253.6 1.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) P34-Arc PF04045.9 EMC94316.1 - 0.024 13.9 0.1 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc RRM_6 PF14259.1 EMC94317.1 - 0.032 14.2 0.0 0.099 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC94317.1 - 0.15 11.7 0.0 1.4 8.6 0.0 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro-kuma_activ PF09286.6 EMC94319.1 - 5.1e-36 123.8 0.0 9.2e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMC94319.1 - 4.7e-06 25.9 0.1 7.5e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Subtilase family ABC2_membrane PF01061.19 EMC94320.1 - 5.7e-37 126.9 21.7 1.1e-36 125.9 15.0 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMC94320.1 - 2.8e-26 92.4 0.1 1.2e-25 90.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EMC94320.1 - 1.3e-07 31.8 0.0 9.4e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EMC94320.1 - 1.4e-06 27.5 22.5 1.4e-06 27.5 15.6 2.2 2 1 1 3 3 3 1 ABC-2 family transporter protein hEGF PF12661.2 EMC94320.1 - 0.001 18.9 27.7 0.033 14.2 0.8 4.9 4 0 0 4 4 4 2 Human growth factor-like EGF AAA_16 PF13191.1 EMC94320.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EMC94320.1 - 0.025 13.9 0.1 0.42 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMC94320.1 - 0.036 13.2 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EMC94320.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain EphA2_TM PF14575.1 EMC94320.1 - 0.15 12.4 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PEPCK_ATP PF01293.15 EMC94320.1 - 0.15 10.5 0.0 0.32 9.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase ABC2_membrane_4 PF12730.2 EMC94320.1 - 1.6 7.8 28.4 0.25 10.4 10.1 3.2 3 1 0 3 3 3 0 ABC-2 family transporter protein EGF_2 PF07974.8 EMC94320.1 - 7.1 6.8 25.8 1.5 9.0 0.9 3.8 3 0 0 3 3 3 0 EGF-like domain ABC2_membrane_2 PF12679.2 EMC94320.1 - 7.4 5.3 26.2 0.017 13.9 8.4 2.5 3 0 0 3 3 3 0 ABC-2 family transporter protein Biotin_lipoyl PF00364.17 EMC94321.1 - 1.6e-20 72.4 1.8 3.8e-20 71.2 1.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMC94321.1 - 3.3e-05 23.4 2.9 0.00012 21.6 0.1 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like E3_binding PF02817.12 EMC94321.1 - 4.9e-05 22.8 0.0 0.00013 21.5 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain DUF2189 PF09955.4 EMC94322.1 - 0.012 15.5 0.4 0.017 15.0 0.3 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) FAM110_N PF14161.1 EMC94322.1 - 0.04 14.1 1.7 0.064 13.5 1.2 1.4 1 0 0 1 1 1 0 Centrosome-associated N terminus AAA PF00004.24 EMC94323.1 - 2.2e-16 60.2 0.0 3.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC94323.1 - 0.0065 16.6 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain adh_short PF00106.20 EMC94324.1 - 1e-32 113.3 1.1 1.8e-32 112.5 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC94324.1 - 9.6e-20 71.3 0.2 1.1e-19 71.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC94324.1 - 1.8e-11 43.9 0.1 3.6e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC94324.1 - 3.6e-07 29.8 0.0 5.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EMC94324.1 - 1.8e-05 24.7 0.0 5.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EMC94324.1 - 0.00028 21.2 0.0 0.031 14.7 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EMC94324.1 - 0.00084 18.1 0.1 0.0011 17.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EMC94324.1 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EMC94324.1 - 0.0031 17.9 0.0 0.0068 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ATP_bind_2 PF03668.10 EMC94324.1 - 0.0067 15.5 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop ATPase protein family RmlD_sub_bind PF04321.12 EMC94324.1 - 0.0086 14.9 0.5 0.014 14.3 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain UDPG_MGDP_dh_N PF03721.9 EMC94324.1 - 0.015 14.7 0.1 0.035 13.4 0.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.10 EMC94324.1 - 0.016 14.0 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EMC94324.1 - 0.021 14.0 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Methyltransf_11 PF08241.7 EMC94324.1 - 0.029 14.8 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 EMC94324.1 - 0.056 13.4 0.2 0.13 12.2 0.0 1.7 2 1 0 2 2 2 0 NADH(P)-binding Grp1_Fun34_YaaH PF01184.14 EMC94325.1 - 7.3e-86 286.8 17.8 8.9e-86 286.5 12.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family WSC PF01822.14 EMC94328.1 - 8.1e-32 109.0 30.1 2.8e-17 62.3 6.0 2.3 2 0 0 2 2 2 2 WSC domain PAN_3 PF08277.7 EMC94328.1 - 0.25 10.9 6.0 4.7 6.8 0.3 2.5 2 0 0 2 2 2 0 PAN-like domain AhpC-TSA PF00578.16 EMC94329.1 - 2.4e-29 101.5 0.0 3.2e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMC94329.1 - 1.3e-12 47.5 0.0 1.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EMC94329.1 - 0.00013 21.5 0.2 0.00026 20.5 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin MARVEL PF01284.18 EMC94330.1 - 0.0017 18.1 19.4 0.0023 17.7 13.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3290 PF11694.3 EMC94330.1 - 1.4 8.6 6.4 0.11 12.2 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4018 PF13210.1 EMC94330.1 - 3.7 6.8 12.0 0.66 9.3 6.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4018) Cu-oxidase_3 PF07732.10 EMC94331.1 - 8e-43 144.9 3.4 8e-43 144.9 2.4 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC94331.1 - 1.3e-34 118.6 7.9 3e-30 104.5 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EMC94331.1 - 1.5e-30 106.2 0.0 5.8e-30 104.3 0.0 2.0 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.9 EMC94333.1 - 1.3e-34 120.0 4.2 3.6e-34 118.5 2.9 1.6 1 1 0 1 1 1 1 Phosphoesterase family FCP1_C PF09309.5 EMC94333.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal VIT1 PF01988.14 EMC94334.1 - 2.3e-49 167.7 10.8 2.8e-49 167.5 7.5 1.1 1 0 0 1 1 1 1 VIT family PrgI PF12666.2 EMC94334.1 - 1.5 9.0 7.4 0.67 10.1 3.1 1.9 2 0 0 2 2 2 0 PrgI family protein Mannosyl_trans PF05007.8 EMC94335.1 - 1e-77 261.2 13.1 1.3e-77 260.9 9.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EMC94335.1 - 4.6e-13 48.7 7.3 9.6e-13 47.7 5.1 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EMC94335.1 - 4.3e-06 26.4 19.2 4.3e-06 26.4 13.3 2.6 1 1 0 2 2 2 1 Protein of unknown function (DUF2029) UbiA PF01040.13 EMC94337.1 - 6.3e-29 100.9 20.6 9.1e-29 100.4 14.3 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Aminotran_1_2 PF00155.16 EMC94340.1 - 1.5e-43 149.1 0.0 1.9e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMC94340.1 - 3.1e-06 25.7 0.0 4.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EMC94340.1 - 3.3e-06 26.4 0.0 5.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EMC94340.1 - 5.6e-05 22.0 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMC94340.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 EMC94340.1 - 0.018 13.7 0.0 0.32 9.6 0.0 2.2 1 1 0 1 1 1 0 Allinase OsmC PF02566.14 EMC94341.1 - 6.7e-15 55.0 0.0 1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Fungal_trans PF04082.13 EMC94342.1 - 9.1e-07 28.0 2.3 1.1e-06 27.7 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94343.1 - 0.036 13.9 12.2 0.11 12.3 8.4 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.20 EMC94344.1 - 2.6e-06 27.4 2.0 4.6e-05 23.4 1.2 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMC94344.1 - 0.00011 22.7 0.7 0.41 11.2 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain ESX-1_EspG PF14011.1 EMC94344.1 - 0.11 11.6 0.4 0.16 11.2 0.3 1.2 1 0 0 1 1 1 0 EspG family WD40 PF00400.27 EMC94346.1 - 4.5e-25 86.5 12.5 6e-07 29.1 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat DPM2 PF07297.7 EMC94347.1 - 2.1e-35 120.8 1.1 2.4e-35 120.6 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EMC94347.1 - 8.3e-05 22.2 1.0 9.3e-05 22.0 0.7 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EMC94347.1 - 0.002 17.9 0.6 0.002 17.9 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 EMC94347.1 - 0.0068 16.2 0.2 0.0068 16.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) Cytochrom_C_asm PF01578.15 EMC94347.1 - 0.0074 15.8 0.1 0.0074 15.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C assembly protein DUF1049 PF06305.6 EMC94347.1 - 0.048 13.1 0.4 0.048 13.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DiS_P_DiS PF06750.8 EMC94347.1 - 0.071 12.9 0.4 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain COX14 PF14880.1 EMC94347.1 - 0.084 12.5 2.4 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Arf PF00025.16 EMC94348.1 - 3.8e-54 182.5 0.0 4.5e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC94348.1 - 6.3e-11 41.5 0.1 3.7e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EMC94348.1 - 4.1e-07 29.3 0.0 5.2e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC94348.1 - 4.1e-07 29.9 0.0 8.5e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMC94348.1 - 4.3e-06 27.2 0.0 5.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EMC94348.1 - 5.7e-06 25.8 0.0 7.3e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC94348.1 - 0.00025 20.2 0.0 0.00027 20.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC94348.1 - 0.069 12.5 0.0 3.7 6.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMC94348.1 - 0.081 12.4 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tegument_dsDNA PF12818.2 EMC94348.1 - 0.17 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein DUF2457 PF10446.4 EMC94349.1 - 2.1e-98 330.0 41.0 2.1e-98 330.0 28.4 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF2457) XPG_N PF00752.12 EMC94351.1 - 4e-35 120.1 0.0 1.1e-34 118.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EMC94351.1 - 1.2e-25 89.3 0.0 2.9e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EMC94351.1 - 0.0019 17.5 3.5 0.0019 17.5 2.4 3.7 3 0 0 3 3 3 1 Ubiquitin interaction motif IMS PF00817.15 EMC94353.1 - 3.3e-40 137.3 0.3 6.9e-40 136.2 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMC94353.1 - 1.3e-17 63.8 0.1 4.9e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMC94353.1 - 0.0016 18.3 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF1675 PF07897.6 EMC94353.1 - 0.024 14.5 4.1 0.028 14.3 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) GGGtGRT PF14057.1 EMC94353.1 - 0.035 12.9 0.5 0.052 12.3 0.3 1.2 1 0 0 1 1 1 0 GGGtGRT protein zf-MIZ PF02891.15 EMC94353.1 - 0.36 10.3 1.7 0.39 10.2 0.3 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger FMN_dh PF01070.13 EMC94354.1 - 5.3e-126 420.2 0.0 6.2e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMC94354.1 - 3.9e-07 29.2 0.1 1.1e-06 27.7 0.0 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMC94354.1 - 1.8e-06 27.1 0.3 7.5e-06 25.0 0.0 2.0 2 1 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EMC94354.1 - 0.0001 21.6 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 EMC94354.1 - 0.00057 19.1 2.2 0.0016 17.6 1.4 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase DHO_dh PF01180.16 EMC94354.1 - 0.024 13.6 0.0 0.053 12.4 0.0 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.9 EMC94354.1 - 0.032 13.3 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.11 EMC94356.1 - 1.4e-21 76.6 32.2 6.9e-14 51.3 1.1 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 EMC94356.1 - 1.2e-09 37.2 3.3 0.00011 20.8 0.0 3.2 2 1 1 3 3 3 3 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EMC94356.1 - 3.6e-09 35.5 12.6 2.9e-05 22.6 1.8 3.4 3 0 0 3 3 3 3 MFS/sugar transport protein Hydrolase_6 PF13344.1 EMC94358.1 - 8.9e-31 105.7 0.0 1.7e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC94358.1 - 1.4e-11 43.9 0.0 3.4e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMC94358.1 - 2.3e-11 44.5 0.0 7.8e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC94358.1 - 9.2e-06 25.9 0.1 0.0054 16.9 0.1 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PDEase_I PF00233.14 EMC94359.1 - 1.3e-19 70.9 0.0 1.7e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Hexokinase_1 PF00349.16 EMC94362.1 - 3.1e-66 222.6 1.2 4e-66 222.2 0.2 1.6 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.11 EMC94362.1 - 1.7e-65 220.6 0.0 1e-64 218.0 0.0 2.1 1 1 0 1 1 1 1 Hexokinase AMP-binding PF00501.23 EMC94363.1 - 3.1e-64 216.9 0.0 4.4e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94363.1 - 2.5e-09 37.9 0.1 5.9e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_31 PF01055.21 EMC94364.1 - 1.8e-90 303.9 12.0 2.8e-90 303.2 8.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMC94364.1 - 1.5e-06 27.9 0.1 5.4e-06 26.1 0.1 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DUF1769 PF08588.5 EMC94366.1 - 3.7e-26 90.8 0.3 7e-26 89.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.15 EMC94367.1 - 1.5e-96 323.4 0.0 2.6e-96 322.5 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CHASE3 PF05227.8 EMC94367.1 - 0.027 14.1 0.3 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 CHASE3 domain Ipi1_N PF12333.3 EMC94369.1 - 8.4e-19 67.4 0.9 4.1e-18 65.2 0.1 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.12 EMC94370.1 - 3.4e-08 32.9 0.0 8.9e-06 25.1 0.0 2.1 1 1 1 2 2 2 2 Roadblock/LC7 domain DUF348 PF03990.9 EMC94370.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF348) DUF1348 PF07080.6 EMC94371.1 - 8.9e-47 158.4 6.9 1.1e-46 158.2 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 EMC94371.1 - 2.3e-07 30.9 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EMC94371.1 - 1.4e-06 28.6 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EMC94371.1 - 0.003 17.1 0.1 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase KGK PF08872.5 EMC94371.1 - 0.19 11.8 3.3 2.6 8.2 1.7 2.3 1 1 1 2 2 2 0 KGK domain Neisseria_TspB PF05616.8 EMC94371.1 - 1.9 6.7 4.5 2.1 6.6 3.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Fungal_trans PF04082.13 EMC94372.1 - 4.6e-19 68.3 0.1 7.7e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94372.1 - 8.1e-08 32.0 9.6 1.6e-07 31.1 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_lectin PF07938.7 EMC94373.1 - 0.00014 21.2 0.4 0.00027 20.3 0.2 1.5 1 1 0 1 1 1 1 Fungal fucose-specific lectin Abhydrolase_6 PF12697.2 EMC94375.1 - 5.7e-29 101.6 0.2 6.8e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC94375.1 - 3e-14 52.9 0.1 3.9e-14 52.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94375.1 - 9.4e-12 44.9 0.0 2e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 EMC94375.1 - 0.00056 20.1 0.0 0.00072 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EMC94375.1 - 0.00067 19.4 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF900 PF05990.7 EMC94375.1 - 0.0047 16.2 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EMC94375.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.2 EMC94375.1 - 0.015 14.1 0.1 0.032 13.1 0.1 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme zf-XS PF03470.9 EMC94375.1 - 0.023 14.7 0.1 0.091 12.8 0.0 2.0 2 0 0 2 2 2 0 XS zinc finger domain DUF659 PF04937.10 EMC94375.1 - 0.033 13.6 0.1 13 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF 659) Ndr PF03096.9 EMC94375.1 - 0.064 11.7 0.1 0.87 8.0 0.0 2.1 2 0 0 2 2 2 0 Ndr family Ser_hydrolase PF06821.8 EMC94375.1 - 0.13 11.8 0.1 0.77 9.3 0.1 2.2 2 1 0 2 2 2 0 Serine hydrolase UPF0183 PF03676.9 EMC94376.1 - 6.9e-37 126.9 0.0 1.4e-25 89.7 0.0 4.4 5 0 0 5 5 5 4 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 EMC94377.1 - 1.1e-107 359.6 0.0 1.1e-107 359.6 0.0 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 EMC94377.1 - 2.3e-07 31.0 2.6 2.3e-07 31.0 1.8 4.5 4 2 1 5 5 5 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 EMC94377.1 - 0.01 15.6 19.1 0.16 11.7 0.0 5.8 2 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus PSRP-3_Ycf65 PF04839.8 EMC94377.1 - 0.18 11.9 2.3 0.56 10.3 0.1 2.9 3 0 0 3 3 3 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) HAD_2 PF13419.1 EMC94377.1 - 0.2 11.8 1.8 39 4.4 0.1 3.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase ERp29 PF07749.7 EMC94377.1 - 1.9 9.1 11.1 16 6.2 0.2 4.6 3 1 2 5 5 5 0 Endoplasmic reticulum protein ERp29, C-terminal domain PAS_9 PF13426.1 EMC94378.1 - 5.1e-19 68.5 0.0 1.4e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EMC94378.1 - 0.0039 16.9 0.0 0.0099 15.6 0.0 1.7 2 0 0 2 2 2 1 PAS fold PQ-loop PF04193.9 EMC94379.1 - 1.4e-33 114.2 2.4 9.1e-16 57.1 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF3357 PF11837.3 EMC94379.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Glyco_tranf_2_3 PF13641.1 EMC94380.1 - 1.2e-06 28.5 0.1 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC94380.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 YL1_C PF08265.6 EMC94381.1 - 0.11 12.0 0.1 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Epimerase PF01370.16 EMC94382.1 - 8.8e-34 116.9 0.0 2.5e-33 115.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EMC94382.1 - 4.5e-13 48.9 0.5 8.6e-13 48.0 0.4 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_4 PF07993.7 EMC94382.1 - 9.7e-07 27.9 0.0 2.5e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EMC94382.1 - 8.2e-06 24.7 0.2 0.00014 20.6 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMC94382.1 - 9.6e-05 21.4 0.0 0.0005 19.0 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EMC94382.1 - 0.0027 17.4 0.0 0.019 14.6 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EMC94382.1 - 0.0031 17.4 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMC94382.1 - 0.0096 15.9 0.1 0.32 10.9 0.0 2.8 3 0 0 3 3 3 1 NADH(P)-binding DAO PF01266.19 EMC94382.1 - 0.046 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMC94382.1 - 0.048 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EMC94382.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EMC94382.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-HC5HC2H_2 PF13832.1 EMC94383.1 - 4.4e-33 113.5 6.9 4.4e-33 113.5 4.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC94383.1 - 1.5e-27 95.5 4.6 1.5e-27 95.5 3.2 2.6 2 1 0 2 2 2 1 PHD-like zinc-binding domain EPL1 PF10513.4 EMC94383.1 - 8.8e-22 78.0 0.0 3.7e-21 76.0 0.0 2.1 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EMC94383.1 - 1.8e-13 49.5 1.5 1.8e-13 49.5 1.0 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EMC94383.1 - 5.2e-09 35.6 23.4 1.9e-08 33.8 6.8 2.5 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 EMC94383.1 - 1.4 8.9 22.1 0.016 15.1 3.5 3.0 2 1 1 3 3 3 0 RING-like domain GCD14 PF08704.5 EMC94386.1 - 2.6e-05 23.8 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EMC94386.1 - 0.016 14.7 0.0 0.17 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_6 PF13921.1 EMC94388.1 - 9.1e-06 25.6 1.0 6.1e-05 23.0 0.1 2.1 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMC94388.1 - 0.0052 16.8 1.7 0.12 12.4 0.0 3.1 2 2 1 3 3 3 1 Myb-like DNA-binding domain DUF2280 PF10045.4 EMC94388.1 - 0.056 13.3 0.2 0.065 13.1 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Shal-type PF11601.3 EMC94388.1 - 0.06 12.8 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels Orbi_NS1 PF01718.11 EMC94388.1 - 0.099 10.6 1.6 0.11 10.4 1.1 1.0 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Cation_efflux PF01545.16 EMC94389.1 - 4.9e-55 186.6 1.4 6.3e-55 186.2 1.0 1.1 1 0 0 1 1 1 1 Cation efflux family Beta-lactamase PF00144.19 EMC94390.1 - 6.9e-45 153.4 2.6 5.4e-44 150.5 1.8 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EMC94390.1 - 0.02 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF1153 PF06627.6 EMC94390.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) His_Phos_2 PF00328.17 EMC94391.1 - 8.4e-49 166.7 0.0 1e-48 166.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FAD_binding_3 PF01494.14 EMC94392.1 - 1.1e-20 74.0 0.1 5.7e-20 71.6 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EMC94392.1 - 1.3e-05 24.1 0.0 5.7e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EMC94392.1 - 8.9e-05 22.4 0.0 0.00022 21.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC94392.1 - 0.00075 18.4 0.0 0.0014 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC94392.1 - 0.0048 17.2 0.0 0.04 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC94392.1 - 0.042 13.7 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC94392.1 - 0.088 11.8 0.8 0.28 10.2 0.6 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Beta-lactamase PF00144.19 EMC94393.1 - 1.2e-47 162.5 0.5 1.6e-47 162.1 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EMC94393.1 - 3.5e-06 26.7 0.0 1.9e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) PQ-loop PF04193.9 EMC94394.1 - 1.7e-23 81.9 7.0 1.5e-13 50.0 2.1 2.6 2 0 0 2 2 2 2 PQ loop repeat FAA_hydrolase_N PF09298.6 EMC94395.1 - 3.2e-23 81.7 0.0 4.8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAA_hydrolase PF01557.13 EMC94395.1 - 0.0001 21.8 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Mur_ligase_M PF08245.7 EMC94396.1 - 3.9e-08 33.5 0.2 3.1e-07 30.6 0.1 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EMC94396.1 - 0.006 16.6 0.1 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain ETF PF01012.16 EMC94396.1 - 0.067 12.9 4.9 3.9 7.1 0.0 2.9 3 1 0 3 3 3 0 Electron transfer flavoprotein domain Cmc1 PF08583.5 EMC94398.1 - 0.029 14.1 1.7 0.072 12.8 1.2 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EMC94398.1 - 0.15 12.1 1.3 0.29 11.2 0.9 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Aldedh PF00171.17 EMC94401.1 - 8.5e-166 551.8 0.7 9.6e-166 551.6 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Flu_NS1 PF00600.14 EMC94401.1 - 0.057 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) DUF3829 PF12889.2 EMC94401.1 - 0.13 11.4 0.0 0.61 9.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Mpv17_PMP22 PF04117.7 EMC94402.1 - 9.4e-26 89.2 4.7 1.7e-25 88.4 3.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family NAPRTase PF04095.11 EMC94403.1 - 4.4e-56 189.9 0.0 3.5e-55 186.9 0.0 1.9 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) family UCH PF00443.24 EMC94404.1 - 7.8e-53 179.3 0.0 9.5e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC94404.1 - 1.7e-16 60.5 1.4 1.9e-15 57.0 0.9 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EMC94404.1 - 1.7e-07 30.4 0.1 4.4e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EMC94404.1 - 0.032 14.4 0.1 0.1 12.8 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain DNA_methylase PF00145.12 EMC94405.1 - 7.7e-47 160.0 0.0 2.8e-36 125.3 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 EMC94405.1 - 0.071 13.1 0.1 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain GATase_2 PF00310.16 EMC94407.1 - 1.4e-20 73.3 0.0 1.7e-16 59.9 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMC94407.1 - 1.8e-16 60.2 0.0 5.5e-16 58.7 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMC94407.1 - 1.2e-14 54.1 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EMC94407.1 - 3.2e-12 46.2 0.0 6.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EMC94407.1 - 1.6e-06 27.0 0.0 2.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Abhydrolase_6 PF12697.2 EMC94408.1 - 5.4e-08 33.0 0.0 6.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94408.1 - 0.00037 20.1 0.0 0.00048 19.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC94408.1 - 0.0079 15.9 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF162 PF02589.10 EMC94408.1 - 0.079 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 RgpF PF05045.7 EMC94409.1 - 0.017 13.6 0.0 0.025 13.1 0.0 1.2 1 0 0 1 1 1 0 Rhamnan synthesis protein F Glucosamine_iso PF01182.15 EMC94410.1 - 9.8e-60 201.6 0.0 1.1e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GMC_oxred_N PF00732.14 EMC94411.1 - 1.3e-50 172.2 0.0 1.7e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC94411.1 - 2.4e-32 112.1 0.0 5.7e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMC94411.1 - 3.4e-08 32.7 5.2 0.00062 18.7 1.1 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMC94411.1 - 1.5e-06 27.3 2.1 0.00014 20.8 0.9 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC94411.1 - 0.0006 19.7 2.3 0.0018 18.2 1.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMC94411.1 - 0.0021 16.7 0.1 0.0032 16.1 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EMC94411.1 - 0.0072 15.2 0.2 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMC94411.1 - 0.018 15.0 0.5 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC94411.1 - 0.022 14.6 0.5 0.048 13.5 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC94411.1 - 0.16 10.7 1.1 1 8.1 0.8 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CorA PF01544.13 EMC94412.1 - 8e-10 38.2 0.7 1.3e-09 37.5 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1767 PF08585.7 EMC94412.1 - 0.091 13.0 0.1 0.46 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1767) ApoL PF05461.6 EMC94412.1 - 0.12 11.5 2.0 0.35 10.0 0.8 1.8 1 1 1 2 2 2 0 Apolipoprotein L RHH_3 PF12651.2 EMC94412.1 - 1.2 8.9 4.8 0.61 9.8 0.5 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix domain F-box-like PF12937.2 EMC94413.1 - 0.0074 15.9 0.1 0.02 14.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like RPA_C PF08784.6 EMC94414.1 - 0.058 13.8 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal Ribosomal_S30 PF04758.9 EMC94415.1 - 4.6e-30 103.1 9.0 4.9e-30 103.0 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pyrid_oxidase_2 PF13883.1 EMC94416.1 - 1.1e-35 122.9 0.0 3.5e-35 121.2 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PAN_1 PF00024.21 EMC94417.1 - 1.1e-12 47.4 21.1 8.9e-08 31.7 0.2 6.0 5 0 0 5 5 5 3 PAN domain PAN_3 PF08277.7 EMC94417.1 - 3.4e-06 26.5 11.8 0.041 13.5 0.2 4.6 4 0 0 4 4 4 3 PAN-like domain PAN_4 PF14295.1 EMC94417.1 - 0.033 13.9 31.7 0.18 11.5 0.3 5.3 5 0 0 5 5 5 0 PAN domain SET PF00856.23 EMC94418.1 - 4.3e-12 46.6 0.0 3.9e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 SET domain ApbA PF02558.11 EMC94420.1 - 6.5e-23 80.8 0.0 1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EMC94420.1 - 2e-21 76.2 0.0 3.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal His_Phos_1 PF00300.17 EMC94421.1 - 5.7e-30 104.5 0.0 6.9e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.19 EMC94422.1 - 7.3e-81 272.0 19.7 9.1e-81 271.7 13.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC94422.1 - 4.7e-24 84.7 31.4 4.7e-24 84.7 21.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC94422.1 - 5.5e-08 31.4 2.8 9.2e-08 30.7 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC94423.1 - 9.5e-60 202.4 10.1 1.1e-59 202.2 7.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC94423.1 - 4.1e-08 32.3 34.3 2e-06 26.7 7.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC94423.1 - 0.14 11.9 2.7 7.2 6.4 0.2 2.7 3 0 0 3 3 3 0 MFS_1 like family DUF4375 PF14300.1 EMC94423.1 - 0.9 9.5 2.7 8.9 6.3 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4375) DUF1479 PF07350.7 EMC94424.1 - 2.2e-127 425.0 0.0 2.5e-127 424.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EMC94424.1 - 0.014 15.4 0.1 0.89 9.5 0.1 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) CorA PF01544.13 EMC94425.1 - 1.2e-12 47.5 0.4 1.6e-12 47.0 0.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 EMC94425.1 - 0.68 7.7 2.1 0.99 7.1 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Hsk3 PF08227.6 EMC94427.1 - 2.5e-19 69.1 3.0 3.7e-19 68.6 2.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF3138 PF11336.3 EMC94427.1 - 0.014 13.5 1.8 0.015 13.4 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FlxA PF14282.1 EMC94427.1 - 0.54 10.2 3.8 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 FlxA-like protein Memo PF01875.12 EMC94428.1 - 2.9e-69 232.9 0.0 3.6e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein IBR PF01485.16 EMC94429.1 - 1.8e-05 24.5 3.6 1.8e-05 24.5 2.5 2.8 2 0 0 2 2 2 2 IBR domain Fe-ADH PF00465.14 EMC94430.1 - 2.8e-76 256.5 0.0 3.2e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMC94430.1 - 5.6e-15 55.3 0.0 7.8e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1967 PF09269.6 EMC94430.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Na_H_Exchanger PF00999.16 EMC94431.1 - 5.4e-71 239.1 50.2 7.4e-71 238.6 34.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3336 PF11815.3 EMC94433.1 - 2.2e-35 121.2 0.6 3.7e-35 120.5 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMC94433.1 - 2.7e-24 86.2 0.0 5.2e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PAN_4 PF14295.1 EMC94434.1 - 0.0063 16.2 1.4 0.011 15.4 1.0 1.5 1 0 0 1 1 1 1 PAN domain WD40 PF00400.27 EMC94435.1 - 4e-29 99.4 5.6 1.3e-07 31.2 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC94435.1 - 2.1e-06 27.5 0.1 0.0093 15.6 0.0 3.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EMC94435.1 - 0.00028 19.8 0.1 0.05 12.3 0.0 2.4 2 1 1 3 3 3 2 Coatomer WD associated region Apc4_WD40 PF12894.2 EMC94435.1 - 0.016 14.6 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EMC94435.1 - 0.062 12.9 2.1 15 5.3 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat E1-E2_ATPase PF00122.15 EMC94436.1 - 5.3e-14 51.7 0.6 1.2e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EMC94436.1 - 4.7e-13 49.7 0.0 1.4e-12 48.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC94436.1 - 3.4e-12 47.2 1.3 1.9e-10 41.5 0.9 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC94436.1 - 1.3e-11 44.2 0.0 3.8e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC94436.1 - 0.0051 16.4 0.3 0.022 14.3 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC94436.1 - 0.049 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DGC PF08859.6 EMC94437.1 - 0.077 12.8 0.5 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 DGC domain HemY_N PF07219.8 EMC94438.1 - 0.1 12.1 0.0 0.1 12.1 0.0 2.9 3 0 0 3 3 3 0 HemY protein N-terminus Phage_int_SAM_5 PF13102.1 EMC94438.1 - 0.18 11.7 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Phage integrase SAM-like domain vATP-synt_E PF01991.13 EMC94439.1 - 7.5e-57 191.8 8.5 8.7e-57 191.5 5.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2196 PF09962.4 EMC94440.1 - 6.4e-23 80.3 2.1 9.4e-23 79.7 1.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) MIF4G PF02854.14 EMC94441.1 - 2.4e-25 89.2 1.4 4.6e-25 88.2 1.0 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EMC94441.1 - 3.9e-22 78.0 0.1 2.4e-21 75.5 0.0 2.4 2 0 0 2 2 2 1 MA3 domain Abhydrolase_2 PF02230.11 EMC94442.1 - 2.4e-30 105.5 0.0 3.7e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMC94442.1 - 1.7e-06 27.8 0.0 3.3e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC94442.1 - 2e-05 24.6 0.5 0.021 14.7 0.1 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC94442.1 - 0.032 13.4 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 EMC94442.1 - 0.065 12.4 0.0 0.34 10.1 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase WD40 PF00400.27 EMC94443.1 - 0.0031 17.3 3.5 0.32 10.9 0.0 4.7 5 1 0 5 5 5 1 WD domain, G-beta repeat PQQ PF01011.16 EMC94443.1 - 0.014 14.8 0.6 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Cu-oxidase_2 PF07731.9 EMC94445.1 - 1.5e-19 69.8 2.1 2.2e-18 66.0 0.6 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMC94445.1 - 1.3e-16 60.3 2.4 2.7e-16 59.3 0.4 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EMC94445.1 - 4.7e-05 23.3 3.6 0.00024 21.0 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.11 EMC94446.1 - 8.2e-39 133.2 27.9 8.2e-39 133.2 19.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC94446.1 - 0.0016 18.2 3.8 3.1 7.6 0.0 4.2 3 1 1 4 4 4 2 MFS_1 like family VanZ PF04892.7 EMC94446.1 - 0.019 14.9 1.1 0.019 14.9 0.7 2.5 3 0 0 3 3 3 0 VanZ like family CcmD PF04995.9 EMC94446.1 - 0.67 9.7 3.3 0.3 10.8 0.2 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF1690 PF07956.6 EMC94447.1 - 5.7e-28 97.6 4.4 1.1e-14 54.5 0.7 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 EMC94447.1 - 0.0048 16.8 2.1 0.0048 16.8 1.4 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF904 PF06005.7 EMC94447.1 - 3 8.1 9.4 1.3 9.3 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Acetyltransf_1 PF00583.19 EMC94448.1 - 3.1e-13 49.5 0.0 4.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC94448.1 - 3e-06 27.2 0.0 4.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC94448.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMC94448.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC94448.1 - 0.096 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 EMC94448.1 - 0.13 12.3 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PsbQ PF05757.6 EMC94449.1 - 0.091 12.1 0.0 0.091 12.1 0.0 1.0 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) adh_short PF00106.20 EMC94450.1 - 9.5e-26 90.6 0.4 1.3e-25 90.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC94450.1 - 4e-15 56.2 0.0 5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMC94450.1 - 2.6e-05 24.3 0.6 0.0007 19.6 0.1 2.4 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EMC94450.1 - 6.6e-05 22.6 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMC94450.1 - 0.00063 19.4 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 EMC94450.1 - 0.0025 17.3 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EMC94450.1 - 0.0038 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Metallophos PF00149.23 EMC94451.1 - 5.7e-45 153.1 0.2 6.9e-45 152.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EMC94452.1 - 2.3e-38 128.6 0.3 4.7e-09 35.7 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat LRR_4 PF12799.2 EMC94455.1 - 1.2e-16 59.8 7.7 9.8e-09 34.6 0.2 3.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC94455.1 - 9.4e-14 50.9 11.8 3.1e-08 33.2 2.2 3.6 2 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EMC94455.1 - 1.2e-08 33.8 6.2 0.016 15.1 0.0 6.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 EMC94455.1 - 2.7e-05 23.7 5.6 10 6.5 0.0 5.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 EMC94455.1 - 0.0038 17.1 11.1 6.1 7.5 0.0 5.7 6 0 0 6 6 6 2 Leucine rich repeat LRR_9 PF14580.1 EMC94455.1 - 0.0078 15.7 0.5 0.015 14.8 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeat Xpo1 PF08389.7 EMC94456.1 - 1.6e-32 112.5 1.4 4.2e-31 107.8 0.0 3.8 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EMC94456.1 - 0.0026 17.6 3.2 0.69 10.1 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat MIS13 PF08202.6 EMC94458.1 - 0.052 12.6 2.2 0.067 12.2 0.5 1.8 1 1 0 2 2 2 0 Mis12-Mtw1 protein family DUF4201 PF13870.1 EMC94458.1 - 0.069 12.5 1.5 0.12 11.7 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Ribosomal_S8 PF00410.14 EMC94460.1 - 2.9e-22 78.9 0.0 3.2e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S8 DUF1654 PF07867.6 EMC94461.1 - 0.019 14.3 1.8 0.033 13.5 0.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1654) HNOBA PF07701.9 EMC94461.1 - 0.1 11.8 0.4 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Heme NO binding associated DUF4407 PF14362.1 EMC94461.1 - 0.19 10.6 2.9 0.24 10.3 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Oxysterol_BP PF01237.13 EMC94461.1 - 2.8 6.3 5.2 3.1 6.1 3.6 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein ADIP PF11559.3 EMC94462.1 - 5.9e-07 29.5 16.2 1.2e-06 28.5 11.2 1.4 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 EMC94462.1 - 2.5e-05 22.2 9.5 3e-05 21.9 6.6 1.0 1 0 0 1 1 1 1 Myosin tail DUF972 PF06156.8 EMC94462.1 - 0.00019 21.7 8.3 0.0013 19.0 0.5 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 EMC94462.1 - 0.0006 19.5 5.8 0.0053 16.5 0.5 2.2 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 EMC94462.1 - 0.00063 19.5 4.7 0.00063 19.5 3.2 1.7 1 1 1 2 2 1 1 Protein of unknown function (DUF1664) BicD PF09730.4 EMC94462.1 - 0.0014 17.0 1.8 0.002 16.5 1.2 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D TelA PF05816.6 EMC94462.1 - 0.0017 17.1 8.5 0.0022 16.7 5.9 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Reo_sigmaC PF04582.7 EMC94462.1 - 0.0023 17.2 0.6 0.0028 16.8 0.4 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EMC94462.1 - 0.0063 16.6 5.3 0.0063 16.6 3.6 2.6 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family DUF4201 PF13870.1 EMC94462.1 - 0.0079 15.6 9.8 0.016 14.6 3.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) AAA_13 PF13166.1 EMC94462.1 - 0.0084 14.6 4.3 0.01 14.3 3.0 1.0 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 EMC94462.1 - 0.0086 15.5 6.7 0.011 15.1 4.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein MCPsignal PF00015.16 EMC94462.1 - 0.0097 15.4 4.2 0.012 15.1 2.9 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain TPR_MLP1_2 PF07926.7 EMC94462.1 - 0.014 15.1 4.3 0.014 15.1 3.0 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EMC94462.1 - 0.016 14.9 0.9 0.24 11.1 0.0 2.7 2 1 1 3 3 2 0 Homeobox associated leucine zipper APG6 PF04111.7 EMC94462.1 - 0.016 14.2 10.3 0.019 14.0 7.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 EMC94462.1 - 0.018 14.5 3.7 0.025 14.1 2.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Vip3A_N PF12495.3 EMC94462.1 - 0.021 14.5 3.2 0.026 14.2 2.3 1.1 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Macoilin PF09726.4 EMC94462.1 - 0.021 13.1 6.1 0.03 12.6 4.3 1.2 1 0 0 1 1 1 0 Transmembrane protein CCDC155 PF14662.1 EMC94462.1 - 0.026 14.1 10.3 0.072 12.6 3.5 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 TBPIP PF07106.8 EMC94462.1 - 0.026 14.0 8.2 0.094 12.2 4.4 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 EMC94462.1 - 0.03 14.2 1.1 1 9.3 0.0 3.0 1 1 2 3 3 3 0 bZIP transcription factor Mnd1 PF03962.10 EMC94462.1 - 0.031 13.9 5.4 0.043 13.4 3.8 1.2 1 0 0 1 1 1 0 Mnd1 family GNT-I PF03071.10 EMC94462.1 - 0.035 12.6 1.9 0.04 12.4 1.3 1.1 1 0 0 1 1 1 0 GNT-I family HlyD PF00529.15 EMC94462.1 - 0.037 13.3 11.7 0.048 12.9 8.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Sec5 PF15469.1 EMC94462.1 - 0.04 13.6 0.8 0.046 13.4 0.1 1.5 2 0 0 2 2 1 0 Exocyst complex component Sec5 Spc7 PF08317.6 EMC94462.1 - 0.05 12.2 5.1 0.072 11.7 3.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Troponin PF00992.15 EMC94462.1 - 0.051 13.6 0.3 0.097 12.7 0.2 1.5 1 1 0 1 1 1 0 Troponin IncA PF04156.9 EMC94462.1 - 0.066 12.8 12.0 0.26 10.8 8.4 1.8 1 1 0 1 1 1 0 IncA protein GAS PF13851.1 EMC94462.1 - 0.074 12.2 6.4 1.3 8.1 5.0 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MbeD_MobD PF04899.7 EMC94462.1 - 0.081 12.8 14.2 0.45 10.4 0.3 3.3 1 1 2 3 3 3 0 MbeD/MobD like Striatin PF08232.7 EMC94462.1 - 0.085 13.1 2.9 0.17 12.1 1.6 1.5 1 1 1 2 2 1 0 Striatin family DUF3450 PF11932.3 EMC94462.1 - 0.098 11.9 16.0 0.51 9.5 11.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Phospholip_B PF04916.8 EMC94462.1 - 0.11 10.6 1.9 0.13 10.3 1.3 1.0 1 0 0 1 1 1 0 Phospholipase B ATG16 PF08614.6 EMC94462.1 - 0.11 12.3 12.8 0.36 10.6 8.9 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4559 PF15112.1 EMC94462.1 - 0.11 11.5 5.1 0.17 11.0 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF342 PF03961.8 EMC94462.1 - 0.12 10.7 1.8 0.14 10.5 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EzrA PF06160.7 EMC94462.1 - 0.12 10.5 7.4 0.24 9.5 5.0 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.3 EMC94462.1 - 0.12 12.0 8.1 2.5 7.8 0.4 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YlqD PF11068.3 EMC94462.1 - 0.12 12.3 16.9 0.037 14.0 2.6 2.2 1 1 1 2 2 2 0 YlqD protein DUF4164 PF13747.1 EMC94462.1 - 0.13 12.4 7.5 0.26 11.4 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF724 PF05266.9 EMC94462.1 - 0.13 11.8 1.1 0.17 11.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Lebercilin PF15619.1 EMC94462.1 - 0.14 11.6 7.3 0.21 11.0 5.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease COG5 PF10392.4 EMC94462.1 - 0.14 12.1 6.5 6.4 6.7 4.3 2.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Vps53_N PF04100.7 EMC94462.1 - 0.14 10.9 2.6 0.21 10.3 1.8 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal Rootletin PF15035.1 EMC94462.1 - 0.2 11.6 14.2 0.42 10.5 9.8 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.4 EMC94462.1 - 0.2 11.7 11.7 1.8 8.7 2.8 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RmuC PF02646.11 EMC94462.1 - 0.22 10.3 9.0 0.081 11.7 2.3 2.1 1 1 1 2 2 2 0 RmuC family NPV_P10 PF05531.7 EMC94462.1 - 0.22 11.7 16.2 0.74 10.1 2.1 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 EMC94462.1 - 0.23 11.3 5.1 0.36 10.7 2.7 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF812 PF05667.6 EMC94462.1 - 0.23 9.9 9.2 0.55 8.6 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 EMC94462.1 - 0.26 9.0 2.4 0.31 8.8 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 EMC94462.1 - 0.26 11.1 9.1 0.77 9.5 2.4 2.0 1 1 1 2 2 2 0 Tropomyosin like TMPIT PF07851.8 EMC94462.1 - 0.27 10.2 4.7 0.34 9.9 3.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ax_dynein_light PF10211.4 EMC94462.1 - 0.3 10.8 6.4 0.78 9.5 4.4 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain Apc4 PF12896.2 EMC94462.1 - 0.31 10.3 3.4 0.47 9.7 1.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 CENP-Q PF13094.1 EMC94462.1 - 0.31 11.0 11.1 0.28 11.1 3.1 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin PF00261.15 EMC94462.1 - 0.31 10.0 4.2 6.2 5.8 0.7 1.9 1 1 0 1 1 1 0 Tropomyosin COG6 PF06419.6 EMC94462.1 - 0.33 9.0 5.9 0.33 9.0 3.6 1.3 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 DUF4618 PF15397.1 EMC94462.1 - 0.34 10.1 9.9 3.1 7.0 1.8 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Mod_r PF07200.8 EMC94462.1 - 0.36 10.7 7.4 0.79 9.6 5.1 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CorA PF01544.13 EMC94462.1 - 0.41 9.6 6.8 0.57 9.1 4.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FANCI_S4 PF14678.1 EMC94462.1 - 0.41 9.7 4.2 0.31 10.1 1.6 1.6 1 1 1 2 2 2 0 FANCI solenoid 4 Atg14 PF10186.4 EMC94462.1 - 0.47 9.3 10.1 1.3 7.9 7.0 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GPO PF05929.6 EMC94462.1 - 0.5 9.5 7.6 0.57 9.3 4.8 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF904 PF06005.7 EMC94462.1 - 0.62 10.3 12.5 0.46 10.8 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) FUSC PF04632.7 EMC94462.1 - 0.66 8.3 5.1 0.76 8.1 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.4 EMC94462.1 - 0.68 9.9 6.3 7.1 6.5 0.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.7 EMC94462.1 - 0.68 10.3 19.9 0.43 10.9 5.0 2.9 1 1 0 2 2 2 0 SlyX Allexi_40kDa PF05549.6 EMC94462.1 - 0.7 9.1 5.3 0.99 8.6 3.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein PspA_IM30 PF04012.7 EMC94462.1 - 0.7 9.2 13.0 0.32 10.3 1.2 2.2 1 1 1 2 2 2 0 PspA/IM30 family DUF4200 PF13863.1 EMC94462.1 - 0.77 9.7 7.3 14 5.6 1.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) FlxA PF14282.1 EMC94462.1 - 0.8 9.6 23.1 37 4.3 16.0 2.3 1 1 0 1 1 1 0 FlxA-like protein Laminin_II PF06009.7 EMC94462.1 - 0.81 9.4 9.8 1.1 8.9 4.8 2.0 1 1 1 2 2 2 0 Laminin Domain II IFT57 PF10498.4 EMC94462.1 - 1.1 7.9 10.4 3.5 6.2 7.2 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 5_nucleotid PF05761.9 EMC94462.1 - 1.1 7.6 4.5 2 6.8 3.1 1.5 1 1 0 1 1 1 0 5' nucleotidase family Lge1 PF11488.3 EMC94462.1 - 1.3 9.2 7.7 8.2 6.6 5.3 2.2 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 bZIP_2 PF07716.10 EMC94462.1 - 1.3 8.9 16.0 1.8 8.4 0.4 4.2 2 1 2 4 4 4 0 Basic region leucine zipper DivIC PF04977.10 EMC94462.1 - 1.3 8.5 14.7 8 6.0 3.6 3.0 1 1 2 3 3 3 0 Septum formation initiator AKNA PF12443.3 EMC94462.1 - 1.5 8.8 8.0 5.5 7.0 3.5 2.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor HAUS-augmin3 PF14932.1 EMC94462.1 - 1.6 7.8 9.8 4.3 6.4 7.0 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CASP_C PF08172.7 EMC94462.1 - 1.9 7.4 7.3 0.92 8.4 1.1 2.1 2 0 0 2 2 2 0 CASP C terminal HrpB7 PF09486.5 EMC94462.1 - 1.9 8.4 8.1 3.8 7.4 5.6 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FliD_C PF07195.7 EMC94462.1 - 2.1 7.6 10.1 1.2 8.4 4.5 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF536 PF04394.9 EMC94462.1 - 2.3 8.0 17.0 0.73 9.6 6.2 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF536 Cluap1 PF10234.4 EMC94462.1 - 2.9 7.0 8.4 6.4 5.8 5.8 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF3847 PF12958.2 EMC94462.1 - 2.9 7.6 7.2 11 5.8 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) Phage_GP20 PF06810.6 EMC94462.1 - 3.2 7.1 10.6 36 3.7 0.3 2.1 1 1 0 1 1 1 0 Phage minor structural protein GP20 Sec20 PF03908.8 EMC94462.1 - 3.6 7.3 5.9 7.8 6.2 1.2 2.3 1 1 1 2 2 2 0 Sec20 FlaC_arch PF05377.6 EMC94462.1 - 4 7.4 4.8 8.8 6.3 1.2 2.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) XhlA PF10779.4 EMC94462.1 - 4.2 7.3 7.8 9.9 6.1 0.5 2.2 1 1 1 2 2 2 0 Haemolysin XhlA Syntaxin PF00804.20 EMC94462.1 - 4.5 7.5 10.9 24 5.1 7.5 2.0 1 1 0 1 1 1 0 Syntaxin Spc24 PF08286.6 EMC94462.1 - 4.5 7.0 10.1 1.8 8.2 4.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UPF0449 PF15136.1 EMC94462.1 - 5.2 7.3 6.4 6.3 7.0 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4404 PF14357.1 EMC94462.1 - 5.6 7.4 9.2 4.3 7.8 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) WXG100 PF06013.7 EMC94462.1 - 7 6.7 15.0 2.1 8.3 2.3 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG FliJ PF02050.11 EMC94462.1 - 8.9 6.3 17.3 17 5.5 7.9 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein DUF948 PF06103.6 EMC94462.1 - 9 6.2 13.4 11 5.8 4.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) EMP24_GP25L PF01105.19 EMC94462.1 - 9.8 5.8 8.2 7.9 6.1 0.3 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD LtrA PF06772.6 EMC94464.1 - 6.3e-17 61.5 22.5 9.1e-17 60.9 15.4 1.4 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Vps5 PF09325.5 EMC94465.1 - 1.1e-81 273.5 0.6 1.6e-81 273.0 0.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EMC94465.1 - 2e-25 88.7 0.0 4.6e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 EMC94465.1 - 0.014 14.6 0.7 0.1 11.8 0.2 2.2 1 1 2 3 3 3 0 WASP-binding domain of Sorting nexin protein CorA PF01544.13 EMC94465.1 - 0.68 8.9 4.5 0.22 10.5 0.5 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HET PF06985.6 EMC94466.1 - 1.1e-23 83.9 0.0 1.9e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SQS_PSY PF00494.14 EMC94468.1 - 1.1e-36 126.5 0.0 1.6e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Rhodanese PF00581.15 EMC94470.1 - 8.1e-17 61.5 0.0 2.4e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PK PF00224.16 EMC94471.1 - 8.1e-170 564.0 5.3 1e-169 563.7 3.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EMC94471.1 - 2.1e-30 104.6 0.0 5.1e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EMC94471.1 - 0.00025 19.9 0.2 0.00076 18.4 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EMC94471.1 - 0.033 13.0 0.0 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.5 EMC94472.1 - 4e-32 109.6 0.0 4.4e-32 109.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) APG6 PF04111.7 EMC94473.1 - 0.012 14.6 1.6 0.015 14.3 1.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Hemerythrin PF01814.18 EMC94473.1 - 0.038 14.1 4.3 0.82 9.8 0.5 2.5 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain M PF02370.11 EMC94473.1 - 0.11 12.8 1.5 0.11 12.8 1.1 2.4 3 0 0 3 3 3 0 M protein repeat HALZ PF02183.13 EMC94473.1 - 0.3 10.8 4.5 0.42 10.3 0.5 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Flagellin_C PF00700.16 EMC94474.1 - 0.26 11.4 1.7 13 6.0 0.1 2.0 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region PSDC PF12588.3 EMC94475.1 - 1.2e-51 174.0 0.0 1.7e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EMC94475.1 - 5.3e-36 123.8 0.0 8.9e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EMC94475.1 - 0.00049 19.6 0.2 0.21 11.2 0.1 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.17 EMC94475.1 - 0.0064 16.0 0.1 0.29 10.7 0.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme PALP PF00291.20 EMC94476.1 - 1.1e-73 248.1 2.6 2.4e-73 247.0 0.9 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EMC94476.1 - 9.1e-44 146.9 0.0 2.2e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Mg_trans_NIPA PF05653.9 EMC94476.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA HIG_1_N PF04588.8 EMC94477.1 - 1.7e-21 75.6 0.0 2.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MAS20 PF02064.10 EMC94477.1 - 0.037 13.9 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor TMF_TATA_bd PF12325.3 EMC94479.1 - 0.01 15.5 1.1 0.013 15.2 0.7 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.1 EMC94479.1 - 0.021 14.7 1.3 0.044 13.7 0.9 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF1255 PF06865.6 EMC94479.1 - 0.051 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1255) Abhydrolase_6 PF12697.2 EMC94480.1 - 9.4e-20 71.4 0.3 1.3e-19 71.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC94480.1 - 3.7e-16 58.7 0.0 6.6e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EMC94480.1 - 4.5e-13 49.1 0.0 9.1e-13 48.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94480.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EMC94480.1 - 0.014 14.3 0.0 0.035 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) PAF-AH_p_II PF03403.8 EMC94480.1 - 0.042 12.1 1.1 2.7 6.1 0.2 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 EMC94480.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Esterase PF00756.15 EMC94480.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 EMC94480.1 - 0.16 10.8 0.0 0.33 9.7 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Myb_DNA-bind_4 PF13837.1 EMC94482.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3336 PF11815.3 EMC94483.1 - 3.9e-51 172.3 3.7 5.9e-51 171.8 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMC94483.1 - 2e-19 70.3 0.1 6.9e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_6 PF12697.2 EMC94483.1 - 0.066 13.0 0.1 0.7 9.7 0.1 2.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_1 PF00175.16 EMC94484.1 - 5.8e-08 33.2 0.0 0.0018 18.8 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMC94484.1 - 3.8e-07 30.1 0.0 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EMC94484.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain AAA PF00004.24 EMC94486.1 - 4.7e-21 75.3 0.0 7.8e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC94486.1 - 2.5e-07 31.5 0.0 4.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC94486.1 - 6.8e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC94486.1 - 0.00062 19.4 0.1 0.005 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) KaiC PF06745.8 EMC94486.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 KaiC RuvB_N PF05496.7 EMC94486.1 - 0.0032 16.5 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC94486.1 - 0.0056 16.8 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC94486.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMC94486.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein IPT PF01745.11 EMC94486.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase RNA_helicase PF00910.17 EMC94486.1 - 0.011 15.9 0.0 0.084 13.0 0.0 2.4 3 1 1 4 4 2 0 RNA helicase AAA_33 PF13671.1 EMC94486.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMC94486.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC94486.1 - 0.013 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMC94486.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.8 EMC94486.1 - 0.025 13.3 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 EMC94486.1 - 0.042 13.7 0.1 0.27 11.1 0.1 1.8 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EMC94486.1 - 0.051 12.4 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EMC94486.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 EMC94486.1 - 0.084 12.4 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC94486.1 - 0.092 13.0 0.1 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF724 PF05266.9 EMC94488.1 - 0.064 12.8 6.5 0.18 11.4 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.2 EMC94488.1 - 0.34 10.7 18.8 1.6 8.5 13.0 2.0 1 1 1 2 2 2 0 Tropomyosin like V_ATPase_I PF01496.14 EMC94488.1 - 2.9 5.6 5.0 3.9 5.1 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EMC94488.1 - 3.6 7.3 11.5 7 6.4 5.1 2.3 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 EMC94488.1 - 4.6 5.8 13.9 4.7 5.7 5.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein GFA PF04828.9 EMC94489.1 - 1.6e-15 56.8 2.1 2.6e-15 56.1 1.5 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme IBR PF01485.16 EMC94490.1 - 0.0011 18.8 17.4 0.0017 18.2 5.3 2.7 1 1 1 2 2 2 2 IBR domain Band_3_cyto PF07565.8 EMC94490.1 - 0.23 10.9 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain zf-NADH-PPase PF09297.6 EMC94490.1 - 0.8 9.2 9.8 0.86 9.1 0.3 3.0 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-UBP PF02148.14 EMC94490.1 - 1.5 8.9 6.9 4.4 7.4 4.8 1.8 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein WD40 PF00400.27 EMC94491.1 - 2.1e-07 30.5 8.0 0.0012 18.6 0.1 5.4 5 1 0 5 5 5 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EMC94491.1 - 0.00055 19.4 0.3 0.017 14.5 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain Nucleoplasmin PF03066.10 EMC94491.1 - 0.0011 18.5 5.4 0.0018 17.7 3.8 1.4 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 EMC94491.1 - 0.0058 14.6 3.1 0.0074 14.2 2.1 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EMC94491.1 - 0.02 12.9 4.0 0.028 12.4 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.6 EMC94491.1 - 0.11 12.2 0.7 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) YL1 PF05764.8 EMC94491.1 - 0.15 11.6 8.2 0.22 11.1 5.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.1 EMC94491.1 - 0.85 9.9 14.5 1.7 9.0 10.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Raffinose_syn PF05691.7 EMC94492.1 - 1.5e-55 188.0 0.7 4.6e-48 163.3 0.1 3.2 1 1 2 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EMC94492.1 - 1.7e-05 23.6 0.4 2.8e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 Melibiase F-box PF00646.28 EMC94493.1 - 0.042 13.5 0.1 0.088 12.4 0.1 1.4 1 0 0 1 1 1 0 F-box domain Pmp3 PF01679.12 EMC94494.1 - 5e-17 61.3 8.7 7e-17 60.8 6.0 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator YrvL PF14184.1 EMC94494.1 - 0.03 14.1 0.0 0.036 13.8 0.0 1.0 1 0 0 1 1 1 0 Regulatory protein YrvL LSM PF01423.17 EMC94495.1 - 2e-10 40.0 0.0 2.3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMC94495.1 - 0.0014 18.4 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF4227 PF14004.1 EMC94495.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF2264 PF10022.4 EMC94496.1 - 4.1e-127 423.7 0.2 5e-127 423.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) PIG-S PF10510.4 EMC94498.1 - 1.9e-136 455.7 0.0 2.2e-136 455.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Acyl-CoA_dh_1 PF00441.19 EMC94499.1 - 2.2e-39 134.9 1.3 3.5e-39 134.2 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC94499.1 - 2.1e-20 71.9 0.3 3.6e-20 71.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EMC94499.1 - 1.4e-19 69.6 0.1 2.9e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EMC94499.1 - 1.5e-16 60.9 0.0 4.6e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMC94499.1 - 1.6e-06 28.4 0.1 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 EMC94499.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP Med8 PF10232.4 EMC94500.1 - 6.9e-22 78.0 0.1 1.8e-21 76.7 0.1 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Nucleoplasmin PF03066.10 EMC94500.1 - 0.0073 15.8 2.9 0.0093 15.4 2.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin PBP1_TM PF14812.1 EMC94500.1 - 0.25 11.6 3.7 0.49 10.7 2.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.8 EMC94500.1 - 3.1 5.4 8.3 4.4 4.9 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Abhydrolase_5 PF12695.2 EMC94501.1 - 2.2e-06 27.5 0.0 1.5e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMC94501.1 - 0.041 13.3 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EMC94501.1 - 0.044 13.0 0.0 0.83 8.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cyclin_N PF00134.18 EMC94503.1 - 3.8e-34 116.9 0.7 7.1e-34 116.1 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC94503.1 - 2.8e-15 56.2 0.9 9.2e-15 54.6 0.6 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain NolV PF06635.7 EMC94503.1 - 0.11 11.5 0.5 0.21 10.7 0.3 1.3 1 0 0 1 1 1 0 Nodulation protein NolV WD40 PF00400.27 EMC94504.1 - 8.2e-06 25.5 17.4 0.089 12.7 0.1 9.2 10 1 1 11 11 11 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EMC94504.1 - 4.4e-05 23.0 0.8 0.0062 16.0 0.1 2.6 1 1 1 2 2 2 2 PQQ-like domain SUR7 PF06687.7 EMC94505.1 - 1.4e-31 109.7 17.3 1.8e-31 109.4 12.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Rad4 PF03835.10 EMC94506.1 - 6.5e-15 54.8 1.7 1.3e-14 53.7 1.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EMC94506.1 - 5.5e-12 45.9 2.3 1.3e-11 44.7 1.6 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.27 EMC94507.1 - 3.7e-22 77.3 29.1 1.5e-07 31.0 0.5 10.6 12 1 0 12 12 12 5 WD domain, G-beta repeat WD40 PF00400.27 EMC94508.1 - 4.7e-18 64.3 5.5 1.7e-05 24.4 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 EMC94509.1 - 2.4e-24 86.4 5.7 5.3e-24 85.3 4.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94509.1 - 3.6e-11 43.0 0.1 1.8e-10 40.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC94509.1 - 4.2e-10 39.5 0.1 1.2e-09 38.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC94509.1 - 4.1e-06 26.5 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EMC94509.1 - 0.069 13.3 0.1 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.6 EMC94509.1 - 0.07 12.8 0.0 9.6 5.8 0.0 2.3 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 EMC94509.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.8 EMC94509.1 - 0.14 11.5 0.1 2.5 7.4 0.0 2.4 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Nitro_FeMo-Co PF02579.12 EMC94509.1 - 0.15 12.1 0.1 0.99 9.5 0.0 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor MFS_1 PF07690.11 EMC94511.1 - 5.2e-42 143.8 29.6 5.2e-42 143.8 20.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC94511.1 - 3.1e-11 42.1 2.9 6.2e-11 41.1 2.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC94511.1 - 6e-07 28.4 26.4 5e-06 25.3 18.3 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.4 EMC94511.1 - 0.01 15.5 4.0 1.1 9.0 0.2 3.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) ORC2 PF04084.9 EMC94511.1 - 0.13 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 FAD_binding_7 PF03441.9 EMC94513.1 - 1.3e-54 185.3 0.3 1.7e-54 184.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMC94513.1 - 8.3e-18 64.6 0.0 1.5e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase UQ_con PF00179.21 EMC94515.1 - 0.048 13.0 0.2 0.51 9.7 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme Synaptobrevin PF00957.16 EMC94516.1 - 2e-28 97.7 3.1 2.4e-28 97.5 2.1 1.0 1 0 0 1 1 1 1 Synaptobrevin Laminin_I PF06008.9 EMC94516.1 - 0.03 13.6 0.8 0.037 13.3 0.5 1.1 1 0 0 1 1 1 0 Laminin Domain I PRT_C PF08372.5 EMC94516.1 - 0.049 13.1 0.1 0.051 13.0 0.1 1.1 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF607 PF04678.8 EMC94516.1 - 0.12 12.2 0.1 0.14 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF607 APG17 PF04108.7 EMC94516.1 - 0.18 10.5 0.8 1.7 7.3 0.0 1.9 1 1 1 2 2 2 0 Autophagy protein Apg17 EMP24_GP25L PF01105.19 EMC94516.1 - 0.26 10.9 2.0 0.39 10.4 1.4 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Lyase_1 PF00206.15 EMC94517.1 - 1.7e-113 378.9 0.0 2.4e-113 378.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EMC94517.1 - 2.2e-22 78.8 0.0 5e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Sel1 PF08238.7 EMC94518.1 - 3.7e-40 135.4 30.4 2e-07 31.3 0.4 7.8 7 0 0 7 7 7 7 Sel1 repeat Glyco_hydro_81 PF03639.8 EMC94518.1 - 0.73 7.7 0.2 1 7.2 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 Zn_clus PF00172.13 EMC94520.1 - 2.6e-08 33.6 8.0 3.8e-08 33.1 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF883 PF05957.8 EMC94521.1 - 1.1e-10 41.7 45.0 0.011 16.1 4.0 4.9 1 1 4 5 5 5 5 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EMC94521.1 - 9.6e-07 29.0 48.0 14 6.0 1.5 6.0 1 1 1 2 2 2 1 YtxH-like protein Macin PF14865.1 EMC94521.1 - 0.0021 18.0 0.3 3.1 7.9 0.0 3.7 3 1 1 4 4 4 2 Macin ATP-synt_B PF00430.13 EMC94521.1 - 0.02 14.7 52.3 0.7 9.6 8.0 4.6 1 1 4 5 5 5 0 ATP synthase B/B' CF(0) MT0933_antitox PF14013.1 EMC94521.1 - 0.02 14.9 43.3 0.79 9.8 3.0 7.1 2 1 4 6 6 6 0 MT0933-like antitoxin protein DivIVA PF05103.8 EMC94521.1 - 0.021 14.8 47.3 3.5 7.6 5.0 4.5 1 1 3 4 4 4 0 DivIVA protein Apolipoprotein PF01442.13 EMC94521.1 - 0.022 14.2 32.5 1.9 7.9 22.6 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PASTA PF03793.14 EMC94521.1 - 1.9 8.2 15.1 16 5.2 0.3 5.4 3 2 2 5 5 5 0 PASTA domain Hormone_1 PF00103.15 EMC94521.1 - 2.8 7.2 13.6 4.6 6.5 1.1 3.4 1 1 2 3 3 3 0 Somatotropin hormone family BMFP PF04380.8 EMC94521.1 - 3.3 7.9 15.8 2.2 8.5 0.3 5.0 1 1 6 7 7 7 0 Membrane fusogenic activity Fasciclin PF02469.17 EMC94522.1 - 1.1e-51 174.1 0.0 5.6e-27 94.2 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_38 PF01074.17 EMC94522.1 - 0.1 11.8 1.8 0.17 11.1 1.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain Sgf11 PF08209.6 EMC94523.1 - 1.1e-11 43.8 2.6 3.3e-11 42.2 0.1 2.3 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EMC94523.1 - 2 8.1 7.8 0.092 12.4 1.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HAD_2 PF13419.1 EMC94525.1 - 3.8e-33 115.1 0.2 4.9e-33 114.7 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC94525.1 - 2e-10 41.4 0.0 1.4e-09 38.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC94525.1 - 4.1e-08 32.8 0.0 6.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EMC94525.1 - 0.0015 18.4 0.0 0.0048 16.7 0.0 2.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Methyltransf_31 PF13847.1 EMC94525.1 - 0.026 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Trehalose_PPase PF02358.11 EMC94525.1 - 0.061 12.2 0.0 0.27 10.0 0.0 2.0 2 0 0 2 2 2 0 Trehalose-phosphatase RecU PF03838.9 EMC94525.1 - 0.088 12.3 0.1 0.67 9.4 0.1 2.0 1 1 0 1 1 1 0 Recombination protein U eIF-1a PF01176.14 EMC94528.1 - 1.3e-28 98.1 0.1 1.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 EMC94529.1 - 5.4e-27 93.7 0.0 8.1e-27 93.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EMC94529.1 - 4.7e-06 26.0 0.3 1.2e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 WH2 motif RecX PF02631.11 EMC94529.1 - 0.026 14.7 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 RecX family zf-C2H2 PF00096.21 EMC94533.1 - 3.3e-09 36.5 12.6 7.8e-05 22.7 1.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC94533.1 - 2.1e-08 34.0 9.7 1.8e-05 24.7 1.3 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC94533.1 - 2.9e-05 24.0 10.1 0.014 15.7 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC94533.1 - 0.0019 18.2 2.1 0.031 14.4 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC94533.1 - 0.0082 16.3 2.8 0.02 15.0 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Peripla_BP_5 PF13433.1 EMC94533.1 - 0.035 12.8 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Zn-ribbon_8 PF09723.5 EMC94533.1 - 0.27 11.2 1.8 8.6 6.4 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Mt_ATP-synt_D PF05873.7 EMC94535.1 - 1.4e-18 67.0 1.7 1.6e-18 66.8 1.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF2799 PF10973.3 EMC94535.1 - 0.052 13.5 0.2 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2799) T2SM_b PF10741.4 EMC94535.1 - 0.09 12.4 0.1 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Pedibin PF08182.6 EMC94535.1 - 0.1 12.1 0.5 0.27 10.7 0.3 1.7 1 0 0 1 1 1 0 Pedibin/Hym-346 family Prefoldin PF02996.12 EMC94535.1 - 0.17 11.5 2.5 0.96 9.1 0.2 2.7 2 1 1 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 EMC94535.1 - 0.17 12.0 2.1 0.24 11.5 0.5 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF148 PF02520.12 EMC94535.1 - 0.22 11.3 4.8 0.073 12.8 1.1 1.8 3 0 0 3 3 3 0 Domain of unknown function DUF148 BLOC1_2 PF10046.4 EMC94535.1 - 0.55 10.4 4.3 0.81 9.8 2.3 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NAC PF01849.13 EMC94536.1 - 5.2e-25 86.7 0.1 1.4e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EMC94536.1 - 0.0035 17.1 0.2 0.0066 16.2 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CENP-B_dimeris PF09026.5 EMC94536.1 - 1.1 9.5 12.8 3.1 8.0 0.8 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Bd3614_N PF14442.1 EMC94536.1 - 1.2 9.0 12.4 2.2 8.2 2.7 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal PBP1_TM PF14812.1 EMC94536.1 - 5.2 7.4 10.8 10 6.5 2.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L14e PF01929.12 EMC94537.1 - 3.3e-19 69.0 0.2 5.2e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EMC94537.1 - 0.0059 16.2 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 KOW motif Glyco_hydro_31 PF01055.21 EMC94538.1 - 1.1e-87 294.7 0.0 1.4e-87 294.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMC94538.1 - 1.8e-11 43.6 0.3 1.2e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.11 EMC94539.1 - 2.7e-25 88.8 32.6 2.7e-25 88.8 22.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3592 PF12158.3 EMC94539.1 - 0.04 13.7 4.2 0.32 10.7 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3592) Abhydrolase_2 PF02230.11 EMC94540.1 - 2.4e-61 206.9 0.0 2.7e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMC94540.1 - 5e-10 39.2 0.0 1.1e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC94540.1 - 2.5e-08 34.1 0.3 6.6e-05 22.9 0.1 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMC94540.1 - 7e-05 22.5 0.0 0.2 11.2 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC94540.1 - 0.00024 20.4 0.2 0.05 12.8 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 EMC94540.1 - 0.00069 18.9 0.0 0.0014 17.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EMC94540.1 - 0.0098 15.3 0.0 0.086 12.2 0.0 2.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 EMC94540.1 - 0.038 13.3 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Cutinase PF01083.17 EMC94540.1 - 0.049 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 EMC94540.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIP PF03583.9 EMC94540.1 - 0.086 12.0 0.1 12 5.0 0.0 2.5 2 1 0 2 2 2 0 Secretory lipase LigB PF02900.13 EMC94541.1 - 9.4e-52 175.6 0.2 1.1e-51 175.4 0.1 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MPC PF03650.8 EMC94542.1 - 5.8e-42 142.4 0.1 7.5e-42 142.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) CTF_NFI PF00859.13 EMC94544.1 - 0.19 11.4 8.6 0.36 10.5 5.9 1.7 1 1 0 1 1 1 0 CTF/NF-I family transcription modulation region adh_short PF00106.20 EMC94545.1 - 9.1e-27 94.0 1.0 1.3e-26 93.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC94545.1 - 1e-17 64.7 0.0 1.2e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC94545.1 - 2.5e-08 33.7 0.7 4.1e-08 33.0 0.5 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMC94545.1 - 0.00075 19.1 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EMC94545.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC94545.1 - 0.0058 15.5 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMC94545.1 - 0.0062 15.2 0.1 0.04 12.6 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EMC94545.1 - 0.0079 15.2 0.1 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EMC94545.1 - 0.011 15.7 1.1 0.038 13.9 0.7 2.0 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMC94545.1 - 0.011 15.4 0.9 0.069 12.9 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Gln-synt_C PF00120.19 EMC94546.1 - 1.9e-50 171.4 0.0 2.5e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain tRNA-synt_1 PF00133.17 EMC94547.1 - 7.4e-148 493.2 0.0 1.5e-147 492.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMC94547.1 - 2.7e-22 79.1 0.2 4.9e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMC94547.1 - 8.8e-20 70.7 0.0 9e-10 37.7 0.0 4.1 3 1 1 4 4 4 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EMC94547.1 - 1.3e-05 24.6 5.2 2.7e-05 23.6 3.6 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EMC94547.1 - 0.00049 19.4 0.0 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EMC94547.1 - 0.071 12.2 0.0 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Cutinase PF01083.17 EMC94548.1 - 2.1e-23 82.9 2.2 2.1e-23 82.9 1.5 2.3 2 1 0 2 2 2 1 Cutinase Abhydrolase_5 PF12695.2 EMC94548.1 - 0.021 14.5 0.5 0.044 13.5 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Mito_carr PF00153.22 EMC94549.1 - 1.2e-70 233.2 0.3 1.1e-24 85.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EMC94549.1 - 3.6e-13 47.7 1.7 6.5e-07 28.2 0.0 4.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC94549.1 - 4.7e-13 47.8 4.2 2.8e-06 26.7 0.0 5.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 EMC94549.1 - 3.3e-11 43.1 1.8 6.6e-07 29.3 0.1 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EMC94549.1 - 7.9e-09 34.9 0.3 0.69 9.5 0.0 4.7 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EMC94549.1 - 2.4e-07 29.7 1.9 8.9e-05 21.6 0.0 3.4 3 0 0 3 3 3 1 EF hand MotA_activ PF09114.5 EMC94549.1 - 0.21 11.3 0.0 7.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain AAA PF00004.24 EMC94550.1 - 1.5e-50 170.8 0.0 7.8e-42 142.5 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC94550.1 - 1.9e-07 31.2 0.1 3.5e-06 27.1 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EMC94550.1 - 1.2e-06 28.0 0.0 5.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EMC94550.1 - 2.3e-06 27.6 0.0 2.7e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EMC94550.1 - 8.3e-05 22.7 0.5 0.0023 18.0 0.0 3.3 3 1 0 3 3 1 1 AAA domain Sigma54_activ_2 PF14532.1 EMC94550.1 - 9.2e-05 22.5 0.0 0.087 12.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 EMC94550.1 - 0.00024 21.0 0.0 0.02 14.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMC94550.1 - 0.00024 20.8 0.0 0.0012 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 EMC94550.1 - 0.0005 19.9 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_25 PF13481.1 EMC94550.1 - 0.00064 19.1 0.0 0.0037 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMC94550.1 - 0.00078 19.3 0.0 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMC94550.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EMC94550.1 - 0.0022 18.8 0.1 0.027 15.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC94550.1 - 0.0054 16.4 0.0 0.021 14.5 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EMC94550.1 - 0.0059 16.9 0.0 0.035 14.3 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EMC94550.1 - 0.01 15.8 0.0 0.08 12.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EMC94550.1 - 0.015 14.0 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EMC94550.1 - 0.019 14.1 0.1 0.06 12.5 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EMC94550.1 - 0.03 13.3 0.1 0.09 11.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EMC94550.1 - 0.032 13.9 0.1 0.09 12.4 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 EMC94550.1 - 0.069 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EMC94550.1 - 0.11 12.0 1.6 0.28 10.7 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMC94550.1 - 0.14 11.8 0.7 1.1 8.8 0.0 2.8 3 1 0 3 3 3 0 Archaeal ATPase ABC_tran PF00005.22 EMC94550.1 - 0.18 12.1 0.0 0.18 12.1 0.0 3.1 3 0 0 3 3 3 0 ABC transporter Torsin PF06309.6 EMC94550.1 - 0.2 11.5 0.1 0.95 9.3 0.0 2.0 2 0 0 2 2 2 0 Torsin NmrA PF05368.8 EMC94551.1 - 7.3e-25 87.5 0.0 9.9e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC94551.1 - 2.9e-09 37.1 0.0 4.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC94551.1 - 0.072 12.5 0.1 3.2 7.1 0.0 2.7 2 2 0 2 2 2 0 NAD dependent epimerase/dehydratase family TRP PF06011.7 EMC94553.1 - 1.1e-97 327.4 6.7 1.5e-97 326.9 4.6 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMC94553.1 - 4.8e-27 94.7 0.0 8e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 ML-like domain DUF3488 PF11992.3 EMC94553.1 - 5.5 5.5 12.1 0.098 11.2 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) DUF896 PF05979.7 EMC94554.1 - 0.094 12.3 0.2 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) C6_DPF PF10170.4 EMC94555.1 - 9.6 6.3 9.4 5.1 7.2 5.0 1.7 1 1 1 2 2 2 0 Cysteine-rich domain Aldo_ket_red PF00248.16 EMC94556.1 - 1.6e-49 168.2 0.0 1.8e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GAS PF13851.1 EMC94557.1 - 0.094 11.8 7.3 0.14 11.3 4.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GerE PF00196.14 EMC94558.1 - 0.009 15.3 0.2 0.65 9.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family Pyr_redox_3 PF13738.1 EMC94559.1 - 8.9e-24 84.6 0.0 4.4e-20 72.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC94559.1 - 2.9e-15 55.4 0.2 1.9e-13 49.4 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMC94559.1 - 3.7e-13 49.0 1.3 2.8e-09 36.3 0.2 3.1 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMC94559.1 - 2.3e-10 39.9 0.1 1.8e-05 23.8 0.0 2.9 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC94559.1 - 5.8e-09 36.1 0.0 0.0024 17.8 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC94559.1 - 9.8e-09 35.1 0.0 2.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMC94559.1 - 1.3e-06 28.2 0.8 0.025 14.3 0.1 2.9 2 1 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMC94559.1 - 0.00013 21.0 0.0 0.0046 15.9 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EMC94559.1 - 0.0014 17.2 0.1 1.2 7.5 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Mqo PF06039.10 EMC94559.1 - 0.0021 16.2 0.0 0.28 9.3 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 EMC94559.1 - 0.0067 15.3 0.0 0.2 10.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMC94559.1 - 0.041 12.9 0.1 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Form-deh_trans PF09163.6 EMC94559.1 - 0.53 9.8 4.7 1.5 8.3 2.4 2.3 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane GTP_EFTU PF00009.22 EMC94561.1 - 2.9e-56 189.8 0.0 4.8e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EMC94561.1 - 6.9e-32 109.1 0.0 1.3e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EMC94561.1 - 4.1e-31 107.0 0.1 8.5e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMC94561.1 - 1.1e-22 79.7 0.0 2.4e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMC94561.1 - 3e-12 46.4 0.3 1.2e-11 44.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EMC94561.1 - 0.015 15.1 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) MMR_HSR1 PF01926.18 EMC94561.1 - 0.079 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EMC94561.1 - 0.13 11.7 0.1 0.47 9.9 0.0 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein WD40 PF00400.27 EMC94562.1 - 2e-33 113.0 7.7 7.7e-10 38.2 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EMC94562.1 - 0.00035 18.8 0.1 0.00071 17.8 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EMC94562.1 - 0.08 12.6 0.0 0.36 10.4 0.0 2.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Translin PF01997.11 EMC94564.1 - 9.5e-54 182.0 0.0 1.2e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Translin family p450 PF00067.17 EMC94565.1 - 2.1e-57 194.6 0.0 2.8e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNARE PF05739.14 EMC94567.1 - 8e-18 63.8 5.5 8e-18 63.8 3.8 2.8 3 0 0 3 3 3 1 SNARE domain ATP-grasp_2 PF08442.5 EMC94567.1 - 0.0052 16.1 0.6 0.0086 15.4 0.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF4094 PF13334.1 EMC94567.1 - 0.0052 17.1 0.9 0.0052 17.1 0.7 2.1 2 1 1 3 3 2 1 Domain of unknown function (DUF4094) Spectrin PF00435.16 EMC94567.1 - 0.013 15.7 12.6 0.16 12.2 0.0 3.2 2 1 0 2 2 2 0 Spectrin repeat TMPIT PF07851.8 EMC94567.1 - 0.038 13.0 2.2 0.95 8.4 0.7 2.1 1 1 0 2 2 2 0 TMPIT-like protein DUF349 PF03993.7 EMC94567.1 - 0.097 12.8 3.4 20 5.4 1.0 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Dispanin PF04505.7 EMC94567.1 - 0.1 12.1 0.8 0.2 11.1 0.6 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein BLOC1_2 PF10046.4 EMC94567.1 - 0.52 10.4 5.7 0.24 11.5 0.8 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.4 EMC94567.1 - 0.95 9.6 11.3 1.4 9.1 0.9 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) FliD_N PF02465.13 EMC94567.1 - 1.2 9.5 7.3 0.64 10.4 2.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus V-SNARE PF05008.10 EMC94567.1 - 1.6 8.9 9.2 0.74 10.0 2.6 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.7 EMC94567.1 - 1.7 8.9 6.1 8.6 6.6 2.5 3.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2721 PF11026.3 EMC94567.1 - 2.1 7.9 7.7 2.8 7.5 0.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) Prominin PF05478.6 EMC94567.1 - 2.9 5.3 12.0 13 3.1 8.5 1.7 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.7 EMC94567.1 - 5 6.9 8.6 9.3 6.0 1.8 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Metallophos PF00149.23 EMC94568.1 - 7.4e-41 139.7 0.2 9.6e-41 139.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S5 PF00333.15 EMC94569.1 - 3.1e-28 97.3 1.6 3.1e-28 97.3 1.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EMC94569.1 - 6.2e-22 76.6 0.1 1.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain EVE PF01878.13 EMC94570.1 - 2.5e-40 137.8 0.4 4.4e-40 136.9 0.3 1.4 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.14 EMC94570.1 - 0.085 12.5 0.5 0.085 12.5 0.3 6.2 6 0 0 6 6 6 0 AT hook motif FHA PF00498.21 EMC94571.1 - 3e-06 27.2 0.0 7.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain PIP5K PF01504.13 EMC94572.1 - 1.3e-59 201.3 0.6 2.7e-59 200.3 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EMC94572.1 - 1.4e-28 99.8 0.0 2.2e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EMC94572.1 - 5.3e-14 51.8 5.1 5.3e-14 51.8 3.5 2.2 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 EMC94572.1 - 0.48 10.1 13.3 0.05 13.3 3.1 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPP1 PF10341.4 EMC94573.1 - 3.8e-08 33.2 0.0 8.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD RFX_DNA_binding PF02257.10 EMC94573.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain adh_short PF00106.20 EMC94575.1 - 2.4e-06 27.5 0.1 8.1e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC94575.1 - 0.0013 18.4 0.1 0.0032 17.1 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMC94575.1 - 0.054 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Aldedh PF00171.17 EMC94576.1 - 7.2e-114 380.6 0.0 9.1e-114 380.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPF0075 PF03702.9 EMC94576.1 - 0.13 11.0 0.0 9.1 5.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0075) Redoxin PF08534.5 EMC94577.1 - 3e-35 120.9 0.0 3.4e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMC94577.1 - 9.9e-11 41.4 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family adh_short PF00106.20 EMC94578.1 - 2.5e-18 66.5 0.3 4e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC94578.1 - 7.8e-09 35.4 0.1 7.8e-09 35.4 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMC94578.1 - 0.00014 21.6 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC94578.1 - 0.0066 15.9 0.0 0.0089 15.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC94578.1 - 0.0079 16.2 0.1 0.02 14.9 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMC94578.1 - 0.15 12.1 0.0 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Rad21_Rec8_N PF04825.8 EMC94579.1 - 2.6e-28 98.1 0.1 4.6e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EMC94579.1 - 3.3e-07 29.3 0.0 6.9e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EMC94579.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 ScpA/B protein Glyco_hydro_76 PF03663.9 EMC94580.1 - 2e-151 504.6 20.8 2.4e-151 504.3 14.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HhH-GPD PF00730.20 EMC94581.1 - 2.4e-08 34.2 0.0 4.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMC94581.1 - 0.039 13.6 0.0 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif YwqJ-deaminase PF14431.1 EMC94581.1 - 0.13 12.1 1.0 1.6 8.5 0.1 2.8 3 0 0 3 3 3 0 YwqJ-like deaminase ICL PF00463.16 EMC94582.1 - 3.1e-197 655.9 0.0 3.6e-197 655.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EMC94582.1 - 1.7e-09 37.2 0.0 2.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Citrate_synt PF00285.16 EMC94583.1 - 6.8e-101 337.5 0.0 8.2e-101 337.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Glyco_trans_2_3 PF13632.1 EMC94584.1 - 1.3e-47 161.9 0.7 1.3e-47 161.9 0.5 2.0 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC94584.1 - 1.2e-06 28.5 0.1 3.5e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC94584.1 - 9e-06 25.4 0.0 5e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMC94584.1 - 4.8e-05 22.7 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 EMC94585.1 - 2.8e-20 72.3 2.1 6.4e-20 71.2 1.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GSH_synth_ATP PF03917.12 EMC94587.1 - 9.7e-73 244.8 0.0 1.2e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EMC94587.1 - 1.5e-26 92.5 0.0 3.2e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase MmgE_PrpD PF03972.9 EMC94588.1 - 3.2e-144 480.4 0.0 5.2e-144 479.7 0.0 1.3 2 0 0 2 2 2 1 MmgE/PrpD family DUF4341 PF14241.1 EMC94589.1 - 1.3 8.7 9.0 1.4 8.7 4.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4341) Rpr2 PF04032.11 EMC94590.1 - 3.1e-17 62.1 1.7 6.7e-17 61.1 1.2 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain ICEA PF05315.6 EMC94590.1 - 0.025 13.9 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 ICEA Protein amfpi-1 PF12190.3 EMC94590.1 - 0.032 14.7 0.6 0.032 14.7 0.4 1.9 2 0 0 2 2 2 0 Fungal protease inhibitor DZR PF12773.2 EMC94590.1 - 0.99 9.2 8.7 2.5 7.9 3.7 2.7 2 1 0 2 2 2 0 Double zinc ribbon DUF678 PF05077.7 EMC94590.1 - 1.9 8.5 7.0 0.093 12.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DEAD PF00270.24 EMC94591.1 - 8.8e-38 129.4 0.2 1.4e-37 128.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC94591.1 - 7.3e-22 77.0 0.0 2.1e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC94591.1 - 5.5e-07 29.5 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nup35_RRM PF05172.8 EMC94592.1 - 0.0032 17.2 0.0 0.006 16.3 0.0 1.4 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Septin PF00735.13 EMC94593.1 - 9.5e-07 28.1 0.0 0.035 13.1 0.0 2.4 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.18 EMC94593.1 - 0.00027 20.8 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC94593.1 - 0.0018 18.7 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EMC94593.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EMC94593.1 - 0.022 14.6 0.1 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMC94593.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_primase_lrg PF04104.9 EMC94594.1 - 8.6e-75 251.3 0.0 1.3e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit A_deaminase PF00962.17 EMC94597.1 - 7.9e-27 94.0 0.3 8e-26 90.7 0.2 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase Exo_endo_phos PF03372.18 EMC94598.1 - 1.1e-09 38.6 0.1 1.3e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_clus PF00172.13 EMC94599.1 - 5.9e-06 26.0 9.3 9.3e-06 25.4 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.8 EMC94601.1 - 1.7e-11 44.1 0.0 2.5e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Cupin_1 PF00190.17 EMC94601.1 - 0.096 12.1 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.2 EMC94601.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Cupin Kelch_4 PF13418.1 EMC94602.1 - 3.8e-19 68.1 0.8 1.8e-09 37.1 0.0 4.9 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC94602.1 - 7.4e-18 64.1 4.9 4.7e-09 36.1 0.0 5.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EMC94602.1 - 1.2e-11 43.9 0.1 0.00029 20.3 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EMC94602.1 - 2.1e-10 40.3 2.7 0.0011 18.9 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EMC94602.1 - 1.3e-09 37.4 0.2 0.00084 19.0 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 EMC94602.1 - 3.6e-09 36.4 0.2 0.005 16.9 0.0 4.6 4 0 0 4 4 4 2 Kelch motif BTB PF00651.26 EMC94602.1 - 0.0033 17.3 0.0 0.0092 15.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain RAG2 PF03089.9 EMC94602.1 - 0.07 11.8 0.0 0.22 10.2 0.0 1.8 1 1 0 1 1 1 0 Recombination activating protein 2 AhpC-TSA PF00578.16 EMC94603.1 - 1.4e-32 111.9 0.0 1.9e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMC94603.1 - 1.6e-13 50.4 0.0 2.1e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EMC94603.1 - 5.8e-12 45.0 0.1 1.1e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin WH2 PF02205.15 EMC94605.1 - 0.0051 16.3 0.8 0.14 11.7 0.1 2.4 2 0 0 2 2 2 2 WH2 motif Histone PF00125.19 EMC94606.1 - 1.1e-14 54.3 0.1 1.2e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC94606.1 - 0.0029 17.7 0.1 0.0034 17.5 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EMC94606.1 - 0.021 14.5 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EMC94606.1 - 0.035 14.1 0.0 0.064 13.3 0.0 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NTF2 PF02136.15 EMC94607.1 - 2.7e-24 85.8 1.1 4.7e-24 85.0 0.8 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EMC94607.1 - 4.7e-09 35.7 0.1 9.2e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC94607.1 - 6.5e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC94607.1 - 0.00016 21.4 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC94607.1 - 0.038 13.8 1.4 0.06 13.2 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 EMC94607.1 - 0.038 13.7 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PCI PF01399.22 EMC94608.1 - 8.1e-11 42.1 0.7 2.9e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 PCI domain RS4NT PF08071.7 EMC94608.1 - 0.11 12.3 0.8 35 4.3 0.0 3.2 3 0 0 3 3 3 0 RS4NT (NUC023) domain G-gamma PF00631.17 EMC94609.1 - 5.3e-22 77.3 0.0 6.2e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 EMC94609.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like HLH PF00010.21 EMC94610.1 - 6.9e-11 41.6 0.0 2.1e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Esterase PF00756.15 EMC94611.1 - 7.1e-54 182.8 0.0 8.9e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EMC94611.1 - 5e-07 29.5 0.0 6.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC94611.1 - 4.3e-05 23.5 0.0 8.1e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC94611.1 - 0.00011 21.5 0.1 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EMC94611.1 - 0.00083 18.6 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EMC94611.1 - 0.00094 18.8 0.0 0.08 12.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EMC94611.1 - 0.002 17.4 0.5 0.017 14.3 0.3 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 EMC94611.1 - 0.0025 16.7 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 EMC94611.1 - 0.0095 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.10 EMC94611.1 - 0.063 12.2 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EMC94611.1 - 0.077 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.6 EMC94611.1 - 0.078 11.7 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.11 EMC94611.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Mpv17_PMP22 PF04117.7 EMC94612.1 - 1.3e-19 69.6 1.0 2.1e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family HHH_3 PF12836.2 EMC94612.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Polysacc_synt_C PF14667.1 EMC94612.1 - 0.58 9.9 3.8 0.77 9.5 0.9 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Rdx PF10262.4 EMC94613.1 - 1e-29 102.3 0.0 1.2e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Rdx family Methyltransf_11 PF08241.7 EMC94615.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NTP_transferase PF00483.18 EMC94615.1 - 0.067 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase NNMT_PNMT_TEMT PF01234.12 EMC94615.1 - 0.3 9.9 0.0 0.48 9.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Peptidase_M22 PF00814.20 EMC94616.1 - 1.4e-47 162.4 0.0 4.4e-45 154.2 0.0 2.9 1 1 0 1 1 1 1 Glycoprotease family DUF1932 PF09130.6 EMC94617.1 - 4.4e-20 71.1 0.1 9.8e-20 70.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 EMC94617.1 - 1.7e-06 28.0 0.0 3.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMC94617.1 - 1.7e-06 28.3 0.0 1.8e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMC94617.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phytase-like PF13449.1 EMC94618.1 - 4e-24 85.4 0.0 8.6e-24 84.3 0.0 1.6 1 1 0 1 1 1 1 Esterase-like activity of phytase DUF2838 PF10998.3 EMC94619.1 - 4.4e-43 145.6 12.1 4.4e-43 145.6 8.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF349 PF03993.7 EMC94619.1 - 0.12 12.5 4.1 0.24 11.5 2.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Val_tRNA-synt_C PF10458.4 EMC94619.1 - 0.18 11.9 3.7 0.83 9.7 0.2 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm GDI PF00996.13 EMC94620.1 - 1.2e-43 149.0 0.0 1.7e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF1198 PF06711.6 EMC94621.1 - 0.16 11.7 0.2 0.26 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Wbp11 PF09429.5 EMC94623.1 - 2.8e-20 72.0 14.0 2.8e-20 72.0 9.7 2.2 3 0 0 3 3 3 1 WW domain binding protein 11 Draxin PF15550.1 EMC94623.1 - 0.55 9.8 10.9 0.75 9.4 7.5 1.2 1 0 0 1 1 1 0 Draxin Borrelia_P83 PF05262.6 EMC94623.1 - 1.6 6.8 8.5 1.8 6.7 5.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PIP5K PF01504.13 EMC94624.1 - 5.7e-28 97.7 0.0 6.8e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MFS_1 PF07690.11 EMC94625.1 - 1.4e-38 132.5 35.0 4.1e-32 111.2 8.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC94625.1 - 8e-12 44.4 1.4 6.7e-10 38.1 0.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EMC94625.1 - 4.7e-11 41.7 0.0 5.5e-06 25.0 0.1 3.6 1 1 1 2 2 2 2 MFS/sugar transport protein Nucleoplasmin PF03066.10 EMC94625.1 - 0.00016 21.1 0.1 0.013 14.9 0.1 2.2 2 0 0 2 2 2 1 Nucleoplasmin BT1 PF03092.11 EMC94625.1 - 0.016 13.9 0.3 5.2 5.6 0.0 2.2 2 0 0 2 2 2 0 BT1 family MFS_1_like PF12832.2 EMC94625.1 - 0.019 14.7 1.1 0.28 10.9 0.0 3.0 2 0 0 2 2 2 0 MFS_1 like family Folate_carrier PF01770.13 EMC94625.1 - 0.14 10.6 0.0 0.23 9.9 0.0 1.4 1 0 0 1 1 1 0 Reduced folate carrier GFO_IDH_MocA PF01408.17 EMC94626.1 - 2.2e-22 79.8 0.2 4.3e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EMC94626.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF2271 PF10029.4 EMC94626.1 - 0.038 13.4 0.1 0.086 12.3 0.1 1.5 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) ECH PF00378.15 EMC94627.1 - 9.3e-24 83.8 0.0 1.1e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ACOX PF01756.14 EMC94628.1 - 6e-38 130.0 0.2 1.2e-37 129.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EMC94628.1 - 3.2e-22 79.1 0.6 7.4e-22 77.9 0.4 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EMC94628.1 - 6.6e-09 35.1 0.0 2.4e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMC94628.1 - 0.00036 20.6 3.9 0.0076 16.3 2.0 2.7 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC94628.1 - 0.042 14.4 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain AMP-binding PF00501.23 EMC94629.1 - 1e-59 202.0 0.0 1.4e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94629.1 - 1.1e-12 48.6 0.0 2.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAP PF02037.22 EMC94630.1 - 5.5e-10 38.5 0.4 3.1e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 SAP domain Nnf1 PF03980.9 EMC94631.1 - 3.9e-18 65.4 0.0 5.6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Nnf1 YqjK PF13997.1 EMC94631.1 - 0.024 14.7 0.1 0.053 13.7 0.1 1.6 1 0 0 1 1 1 0 YqjK-like protein SGL PF08450.7 EMC94632.1 - 5.7e-60 202.7 0.1 7.5e-60 202.3 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region bZIP_2 PF07716.10 EMC94637.1 - 0.0063 16.3 13.4 0.013 15.2 9.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC94637.1 - 0.04 14.2 8.5 0.076 13.3 5.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TFIIA PF03153.8 EMC94637.1 - 0.91 9.3 3.7 1.6 8.5 2.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mur_ligase_M PF08245.7 EMC94638.1 - 0.0017 18.4 0.0 2 8.4 0.0 3.1 2 1 0 2 2 2 2 Mur ligase middle domain MutS_V PF00488.16 EMC94639.1 - 8e-82 274.1 0.0 1.2e-81 273.6 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC94639.1 - 2e-47 161.6 0.0 3.2e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EMC94639.1 - 3.3e-34 117.2 0.1 3.8e-33 113.8 0.0 2.6 3 0 0 3 3 3 1 MutS domain I MutS_IV PF05190.13 EMC94639.1 - 1.1e-16 60.7 0.3 2.3e-16 59.7 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EMC94639.1 - 7e-12 45.5 0.0 1.7e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 EMC94639.1 - 0.0057 16.9 1.6 0.035 14.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMC94639.1 - 0.011 15.2 0.1 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EMC94639.1 - 0.16 11.8 3.2 0.2 11.6 0.1 2.5 3 0 0 3 3 3 0 AAA domain Ebola_NP PF05505.7 EMC94639.1 - 7.5 4.4 7.5 12 3.8 5.2 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein adh_short PF00106.20 EMC94642.1 - 4.2e-16 59.3 0.0 1.7e-15 57.3 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EMC94642.1 - 2.9e-06 26.9 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC94642.1 - 6.8e-06 26.2 0.2 9e-06 25.8 0.2 1.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMC94642.1 - 2.6e-05 23.9 0.1 5.3e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMC94642.1 - 0.00079 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 EMC94642.1 - 0.028 14.8 0.4 0.06 13.7 0.3 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1771 PF08590.5 EMC94642.1 - 0.089 12.8 3.2 0.09 12.7 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) TrkA_N PF02254.13 EMC94642.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Toprim_4 PF13662.1 EMC94642.1 - 0.13 12.2 0.1 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Trehalase PF01204.13 EMC94647.1 - 0.053 12.1 0.1 0.081 11.5 0.1 1.2 1 0 0 1 1 1 0 Trehalase MSP1_C PF07462.6 EMC94651.1 - 4.4 5.5 5.6 4.7 5.4 3.9 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cytochrom_B561 PF03188.11 EMC94654.1 - 1.4e-06 28.2 5.4 3.7e-06 26.8 3.6 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF998 PF06197.8 EMC94654.1 - 0.74 9.0 16.4 0.64 9.3 5.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF998) Aldedh PF00171.17 EMC94655.1 - 3.7e-177 589.2 0.2 4.3e-177 589.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC94655.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Amidase PF01425.16 EMC94658.1 - 1e-76 258.6 0.2 2.3e-75 254.1 0.1 2.0 1 1 0 1 1 1 1 Amidase Polysacc_syn_2C PF08485.5 EMC94658.1 - 0.13 11.7 0.8 19 4.8 0.1 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal Scytalone_dh PF02982.9 EMC94659.1 - 0.12 11.9 0.1 0.5 9.9 0.0 1.9 1 1 1 2 2 2 0 Scytalone dehydratase CBP4 PF07960.6 EMC94659.1 - 0.13 11.9 3.2 0.068 12.7 0.3 1.9 1 1 1 2 2 2 0 CBP4 Cortex-I_coil PF09304.5 EMC94659.1 - 2.1 8.4 6.2 0.4 10.7 0.5 2.3 3 0 0 3 3 3 0 Cortexillin I, coiled coil CS PF04969.11 EMC94660.1 - 3.9e-17 62.5 0.1 8.4e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 CS domain ATP-synt_DE_N PF02823.11 EMC94661.1 - 4.6e-20 71.1 0.1 6.6e-20 70.6 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GH114_assoc PF14741.1 EMC94662.1 - 0.048 13.3 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Reo_sigmaC PF04582.7 EMC94663.1 - 2.3e-05 23.7 38.4 0.0013 17.9 3.5 5.1 2 2 3 5 5 5 4 Reovirus sigma C capsid protein DivIC PF04977.10 EMC94663.1 - 0.0071 15.8 2.6 0.0071 15.8 1.8 12.0 7 5 5 13 13 13 3 Septum formation initiator Tropomyosin_1 PF12718.2 EMC94663.1 - 0.0077 16.0 23.1 0.0077 16.0 16.0 7.6 5 2 3 8 8 8 2 Tropomyosin like LPP PF04728.8 EMC94663.1 - 0.14 11.9 12.8 0.78 9.5 0.1 5.3 5 1 0 5 5 5 0 Lipoprotein leucine-zipper Atg14 PF10186.4 EMC94663.1 - 0.19 10.6 87.9 0.022 13.7 8.5 6.1 3 1 3 6 6 6 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EMC94663.1 - 0.71 10.1 52.6 2.8 8.2 0.5 9.8 4 4 6 10 10 10 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EMC94663.1 - 2.4 7.7 125.2 0.022 14.3 10.4 8.6 2 1 3 5 5 5 0 IncA protein Alpha-L-AF_C PF06964.7 EMC94664.1 - 3.5e-25 88.8 0.1 7.6e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Fungal_trans_2 PF11951.3 EMC94665.1 - 1.2e-09 37.3 1.2 2.1e-09 36.4 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94665.1 - 8.8e-08 31.9 9.6 2e-07 30.8 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.11 EMC94668.1 - 4e-26 91.8 0.0 6.2e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMC94668.1 - 6.1e-15 55.1 0.0 2.4e-09 36.8 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain adh_short PF00106.20 EMC94670.1 - 1e-14 54.8 5.3 3.2e-13 49.9 3.6 2.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMC94670.1 - 1.2e-06 28.0 0.3 8.1e-06 25.4 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMC94670.1 - 6.4e-06 25.9 2.0 0.0011 18.7 1.4 2.8 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EMC94670.1 - 0.00082 18.3 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMC94670.1 - 0.003 17.5 1.2 0.004 17.1 0.9 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMC94670.1 - 0.012 14.2 0.4 0.041 12.5 0.2 1.7 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4320 PF14208.1 EMC94670.1 - 0.098 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Amidohydro_2 PF04909.9 EMC94670.1 - 0.11 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase Cupin_2 PF07883.6 EMC94671.1 - 4.5e-13 48.4 0.3 5.7e-13 48.1 0.2 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EMC94671.1 - 8.4e-10 38.2 0.0 9.8e-10 38.0 0.0 1.0 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EMC94671.1 - 0.0037 16.8 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Cupin DUF4437 PF14499.1 EMC94671.1 - 0.0048 15.8 0.0 0.0053 15.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_3 PF05899.7 EMC94671.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMC94671.1 - 0.045 13.4 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain Peptidase_C14 PF00656.17 EMC94671.1 - 0.047 13.3 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Caspase domain AMP-binding PF00501.23 EMC94672.1 - 1.2e-61 208.3 0.0 1.5e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94672.1 - 1.8e-14 54.4 0.0 4.1e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNase_PH PF01138.16 EMC94673.1 - 9.3e-20 71.2 0.0 1.8e-19 70.3 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 SnoaL PF07366.7 EMC94675.1 - 0.067 12.7 0.1 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Cyclin PF08613.6 EMC94676.1 - 1e-12 48.6 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMC94676.1 - 0.0077 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain LINES_N PF14694.1 EMC94677.1 - 0.13 11.4 0.2 0.2 10.8 0.1 1.5 1 1 0 1 1 1 0 Lines N-terminus ECH PF00378.15 EMC94678.1 - 3.1e-40 137.8 0.1 3.6e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF287 PF03384.9 EMC94678.1 - 0.1 12.7 0.6 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 ADH_N PF08240.7 EMC94679.1 - 1.6e-26 92.1 0.5 3e-26 91.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC94679.1 - 3.9e-07 29.6 0.4 7.3e-07 28.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EMC94679.1 - 0.00076 18.0 0.3 0.0029 16.1 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein ADH_N_assoc PF13823.1 EMC94679.1 - 0.00086 18.9 0.0 0.0039 16.8 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Pro_isomerase PF00160.16 EMC94680.1 - 8.4e-53 178.7 0.0 9.6e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 EMC94682.1 - 5.1e-56 189.6 0.0 5.1e-55 186.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC94682.1 - 2.4e-27 95.6 0.1 2.7e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EMC94682.1 - 1.6e-05 25.3 0.1 1.6e-05 25.3 0.0 2.5 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC94682.1 - 0.00069 18.6 0.1 0.0045 16.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC94682.1 - 0.04 13.6 5.1 0.24 11.1 0.0 3.6 3 1 0 4 4 4 0 Phosphotransferase enzyme family GATA PF00320.22 EMC94683.1 - 9.4e-17 60.0 2.1 1.9e-16 59.0 1.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EMC94683.1 - 2e-13 49.6 2.9 3.6e-13 48.8 2.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) EF-1_beta_acid PF10587.4 EMC94683.1 - 0.18 11.9 0.8 0.35 11.0 0.6 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF2328 PF10090.4 EMC94685.1 - 0.087 12.0 0.7 0.14 11.3 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2328) DLH PF01738.13 EMC94687.1 - 6.6e-20 71.3 0.0 7.7e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC94687.1 - 0.00036 20.2 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94687.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 EMC94688.1 - 4.6e-54 183.2 0.0 7.3e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC94688.1 - 3.4e-34 118.0 0.0 1.7e-33 115.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC94688.1 - 3.1e-06 26.3 0.0 5.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cep57_CLD_2 PF14197.1 EMC94688.1 - 8.2e-06 25.6 2.3 8.2e-06 25.6 1.6 2.0 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 APH PF01636.18 EMC94688.1 - 0.0068 16.1 0.7 0.067 12.9 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinesin-relat_1 PF12711.2 EMC94688.1 - 0.045 14.1 2.3 11 6.4 0.0 2.7 2 1 0 2 2 2 0 Kinesin motor BTB PF00651.26 EMC94689.1 - 4.1e-22 78.2 0.0 5.3e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 EMC94689.1 - 5.7e-11 41.6 0.2 1.4e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMC94689.1 - 1.6e-08 34.8 0.0 4.6e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC94689.1 - 2.4e-08 34.2 0.0 5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC94689.1 - 4.9e-08 32.9 0.0 1.5e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC94689.1 - 0.0021 18.1 0.1 0.062 13.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat AATase PF07247.7 EMC94690.1 - 2.3e-22 79.2 0.0 1.4e-21 76.6 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Transferase PF02458.10 EMC94690.1 - 0.046 12.1 0.3 0.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Transferase family WES_acyltransf PF03007.11 EMC94690.1 - 0.079 12.5 2.1 0.15 11.5 0.3 2.1 2 1 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Ctr PF04145.10 EMC94691.1 - 1.8e-36 125.3 0.1 2.1e-36 125.1 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF2975 PF11188.3 EMC94691.1 - 0.66 9.6 3.0 1 9.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Ferritin_2 PF13668.1 EMC94692.1 - 8.6e-25 87.2 6.4 1.9e-22 79.6 4.5 2.3 1 1 0 1 1 1 1 Ferritin-like domain RGS PF00615.14 EMC94694.1 - 7.4e-07 29.2 0.0 7e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Acetyltransf_7 PF13508.1 EMC94695.1 - 4.7e-11 42.6 0.2 6.3e-11 42.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC94695.1 - 1e-10 41.4 0.1 1.5e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMC94695.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pox_T4_N PF04491.7 EMC94695.1 - 0.12 12.2 0.4 0.3 10.9 0.1 1.8 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus AdoMet_MTase PF07757.8 EMC94696.1 - 5.9e-41 139.0 0.0 1e-39 135.1 0.0 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EMC94696.1 - 0.013 15.2 0.0 0.054 13.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EMC94696.1 - 0.033 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMC94696.1 - 0.071 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EMC94698.1 - 4.3e-67 226.0 0.0 1.8e-66 223.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC94698.1 - 7.8e-31 107.0 0.0 1.9e-30 105.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC94698.1 - 1.5e-05 24.8 0.1 0.00028 20.7 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC94698.1 - 3.2e-05 23.5 0.0 8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EMC94698.1 - 0.00019 20.5 0.0 0.00047 19.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EMC94698.1 - 0.38 9.3 1.3 5.6 5.4 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1679) Fe_hyd_lg_C PF02906.9 EMC94699.1 - 0.25 10.5 0.3 0.37 9.9 0.2 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Form_Nir_trans PF01226.12 EMC94700.1 - 1.4e-75 253.4 21.6 1.6e-75 253.2 15.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Ycf4 PF02392.11 EMC94700.1 - 0.74 9.1 4.6 0.12 11.6 0.3 1.9 2 0 0 2 2 2 0 Ycf4 Polysacc_synt_4 PF04669.8 EMC94701.1 - 5.1e-24 84.6 2.4 2.7e-23 82.3 1.7 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis UPF0158 PF03682.8 EMC94701.1 - 0.017 14.7 0.7 0.031 13.8 0.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0158) Microtub_bind PF13931.1 EMC94701.1 - 0.046 13.8 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding ABC_membrane PF00664.18 EMC94702.1 - 4.2e-77 259.2 25.7 1.3e-42 146.1 6.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC94702.1 - 1.1e-56 190.9 0.0 1.7e-28 99.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC94702.1 - 1.8e-14 53.4 4.4 9.9e-06 24.9 0.8 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC94702.1 - 2.8e-11 43.9 0.1 0.009 16.0 0.0 3.8 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EMC94702.1 - 1.3e-09 37.4 0.3 0.0011 18.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EMC94702.1 - 2.9e-09 36.5 0.2 0.056 12.8 0.0 3.8 3 0 0 3 3 3 3 AAA domain AAA_22 PF13401.1 EMC94702.1 - 4.2e-09 36.6 0.0 0.0002 21.4 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 EMC94702.1 - 3.7e-07 30.9 0.0 0.019 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EMC94702.1 - 3.9e-06 25.7 9.2 0.00015 20.4 0.3 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMC94702.1 - 4e-06 26.9 2.3 0.013 15.5 0.3 3.6 3 1 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 EMC94702.1 - 4.3e-06 25.9 0.0 0.13 11.4 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMC94702.1 - 3e-05 24.3 0.0 0.4 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EMC94702.1 - 4.7e-05 23.0 0.2 0.018 14.7 0.0 3.4 2 1 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EMC94702.1 - 0.00012 21.5 7.3 0.84 9.0 0.0 4.8 5 0 0 5 5 5 2 AAA-like domain AAA_33 PF13671.1 EMC94702.1 - 0.00094 19.0 0.0 0.37 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EMC94702.1 - 0.0011 19.3 0.2 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EMC94702.1 - 0.0019 17.7 0.1 1 8.7 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_5 PF07728.9 EMC94702.1 - 0.0026 17.4 0.6 2.7 7.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EMC94702.1 - 0.0026 17.6 1.0 1.3 8.9 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Sigma54_activat PF00158.21 EMC94702.1 - 0.0035 16.8 0.0 0.9 8.9 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF3987 PF13148.1 EMC94702.1 - 0.0039 15.8 0.0 1.6 7.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.18 EMC94702.1 - 0.0051 16.7 0.0 3.1 7.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_13 PF13166.1 EMC94702.1 - 0.0064 15.0 0.1 1.3 7.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.15 EMC94702.1 - 0.0092 15.6 0.8 2 8.0 0.0 3.0 3 0 0 3 3 3 1 Adenylylsulphate kinase PRK PF00485.13 EMC94702.1 - 0.02 14.4 0.0 2.2 7.8 0.0 3.0 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EMC94702.1 - 0.02 15.0 0.0 7.2 6.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.18 EMC94702.1 - 0.037 13.4 1.3 14 5.0 0.1 3.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP-synt_ab PF00006.20 EMC94702.1 - 0.053 13.0 1.8 33 3.8 0.0 3.5 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 EMC94702.1 - 0.056 13.2 4.2 0.21 11.3 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 Sigma54_activ_2 PF14532.1 EMC94702.1 - 0.069 13.2 0.0 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain MobB PF03205.9 EMC94702.1 - 0.11 12.1 0.1 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EMC94702.1 - 0.27 10.2 0.0 8.4 5.3 0.0 2.4 3 0 0 3 3 2 0 AAA ATPase domain KaiC PF06745.8 EMC94702.1 - 0.59 9.2 3.8 17 4.4 0.0 3.2 3 0 0 3 3 3 0 KaiC F-box-like PF12937.2 EMC94704.1 - 0.026 14.2 0.0 0.12 12.1 0.0 2.2 1 1 0 1 1 1 0 F-box-like Antigen_Bd37 PF11641.3 EMC94704.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein adh_short PF00106.20 EMC94705.1 - 2.6e-30 105.5 1.1 3.5e-30 105.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC94705.1 - 1.8e-27 96.7 0.0 2.1e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC94705.1 - 1.4e-16 60.7 0.3 2e-16 60.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC94705.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Herpes_UL3 PF03369.8 EMC94706.1 - 0.063 13.2 1.1 0.11 12.4 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL3 protein Sugar_tr PF00083.19 EMC94708.1 - 1.2e-112 376.8 32.4 1.6e-112 376.3 22.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC94708.1 - 3.9e-21 75.1 50.7 1.6e-16 59.9 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EMC94711.1 - 8.1e-29 100.4 26.9 8.1e-29 100.4 18.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC94711.1 - 9.4e-05 20.7 3.8 0.00015 20.1 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_1 PF00583.19 EMC94712.1 - 8.2e-09 35.3 0.1 1.7e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC94712.1 - 4.4e-08 33.1 0.1 4.2e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC94712.1 - 3.4e-07 30.3 0.0 8.6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC94712.1 - 0.0023 17.8 0.2 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC94712.1 - 0.086 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Lactamase_B PF00753.22 EMC94713.1 - 7.4e-17 61.6 5.2 9.4e-17 61.3 3.6 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC94713.1 - 0.036 13.6 0.3 0.055 13.0 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CTP_transf_2 PF01467.21 EMC94714.1 - 0.0051 16.8 0.3 0.054 13.5 0.4 2.5 2 1 0 2 2 2 1 Cytidylyltransferase Ead_Ea22 PF13935.1 EMC94715.1 - 0.0095 16.2 4.4 0.0095 16.2 3.1 1.9 2 0 0 2 2 2 1 Ead/Ea22-like protein Choline_kinase PF01633.15 EMC94715.1 - 0.12 11.9 0.4 0.23 11.0 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Filament PF00038.16 EMC94715.1 - 0.23 10.9 16.1 0.11 11.8 7.1 2.4 1 1 2 3 3 3 0 Intermediate filament protein FlxA PF14282.1 EMC94715.1 - 2.2 8.2 12.4 2.6 8.0 7.5 2.0 1 1 0 1 1 1 0 FlxA-like protein Seryl_tRNA_N PF02403.17 EMC94715.1 - 7.3 6.6 13.1 0.82 9.7 1.9 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Ribophorin_II PF05817.9 EMC94716.1 - 4.2e-20 71.5 0.0 4.7e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Pex14_N PF04695.8 EMC94718.1 - 4.9 7.2 7.6 16 5.5 5.3 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M28 PF04389.12 EMC94721.1 - 4.4e-36 124.2 0.0 6.1e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Spc7_N PF15402.1 EMC94722.1 - 1.4e-77 261.6 75.6 5.4e-62 210.0 13.0 4.8 2 1 3 5 5 5 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EMC94722.1 - 2.1e-77 259.9 9.0 3.4e-77 259.3 6.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EMC94722.1 - 4.7e-06 26.1 0.0 9.1e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 Atg14 PF10186.4 EMC94722.1 - 9.3 5.0 14.2 3.4 6.5 6.2 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_S17 PF00366.15 EMC94723.1 - 4.8e-30 103.4 0.8 7.4e-30 102.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Apolipoprotein PF01442.13 EMC94724.1 - 0.011 15.2 6.1 0.019 14.5 4.2 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CesA PF11439.3 EMC94724.1 - 0.03 14.2 0.4 0.035 14.0 0.3 1.1 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Acetyltransf_11 PF13720.1 EMC94724.1 - 0.076 13.2 1.0 0.68 10.1 0.2 2.1 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pfg27 PF09216.5 EMC94724.1 - 0.099 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Pfg27 HAUS-augmin3 PF14932.1 EMC94724.1 - 0.11 11.7 2.9 0.13 11.4 2.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 KSR1-SAM PF13543.1 EMC94724.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.5 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Elongin_A PF06881.6 EMC94724.1 - 0.13 12.6 2.9 1.9 8.9 1.7 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ring_hydroxyl_A PF00848.14 EMC94724.1 - 0.15 11.7 1.6 0.15 11.6 1.1 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) ARGLU PF15346.1 EMC94724.1 - 0.24 11.1 11.4 0.3 10.8 7.9 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 ISG65-75 PF11727.3 EMC94724.1 - 0.58 9.1 4.3 0.57 9.1 2.2 1.5 1 1 1 2 2 2 0 Invariant surface glycoprotein MerR-DNA-bind PF09278.6 EMC94724.1 - 1.2 9.6 5.2 3.4 8.1 1.6 2.4 1 1 0 2 2 2 0 MerR, DNA binding GreA_GreB_N PF03449.10 EMC94724.1 - 1.3 9.1 8.0 0.44 10.6 0.5 2.9 2 1 0 2 2 2 0 Transcription elongation factor, N-terminal IncA PF04156.9 EMC94724.1 - 1.5 8.3 5.9 2 7.9 4.1 1.2 1 0 0 1 1 1 0 IncA protein Cyt-b5 PF00173.23 EMC94725.1 - 4.8e-15 55.1 0.0 6.7e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SET PF00856.23 EMC94728.1 - 1.4e-19 70.9 0.3 9.6e-19 68.2 0.2 2.1 1 1 0 1 1 1 1 SET domain DUF1936 PF09151.5 EMC94728.1 - 0.0076 15.7 0.6 0.017 14.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1936) DUF4119 PF13494.1 EMC94728.1 - 0.081 12.9 0.3 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF1071 PF06378.6 EMC94728.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1071) But2 PF09792.4 EMC94729.1 - 5.1e-35 120.3 0.2 1.1e-34 119.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain MRP-S26 PF14943.1 EMC94730.1 - 0.74 9.3 0.0 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 NGP1NT PF08153.7 EMC94731.1 - 1.3e-44 151.2 0.1 2.4e-44 150.4 0.1 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EMC94731.1 - 7.1e-19 67.8 0.0 4.7e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC94731.1 - 0.00038 20.3 0.0 0.44 10.3 0.0 3.5 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EMC94731.1 - 0.00049 19.3 0.0 0.00096 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EMC94731.1 - 0.00051 19.3 0.1 0.0012 18.1 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EMC94731.1 - 0.0025 17.0 0.1 0.084 12.1 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC94731.1 - 0.02 14.3 0.0 3.7 6.9 0.0 3.1 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain UvrD_C PF13361.1 EMC94732.1 - 3.2e-74 250.5 0.0 5.1e-74 249.8 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EMC94732.1 - 1.5e-59 201.8 6.4 1.6e-58 198.4 1.9 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EMC94732.1 - 8.5e-12 45.1 0.1 3.3e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EMC94732.1 - 1.5e-10 40.6 0.1 9e-10 38.1 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMC94732.1 - 1.6e-05 24.5 0.5 0.0028 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC94732.1 - 0.0026 17.9 0.4 0.24 11.5 0.0 2.8 1 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EMC94732.1 - 0.011 14.6 0.1 0.021 13.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CDC27 PF09507.5 EMC94732.1 - 2.1 7.5 13.9 0.06 12.5 0.2 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 FKBP_C PF00254.23 EMC94733.1 - 4.9e-33 113.0 0.0 6e-33 112.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AfsA PF03756.8 EMC94733.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain AMP-binding PF00501.23 EMC94734.1 - 3.1e-68 230.1 0.2 7.7e-68 228.7 0.1 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94734.1 - 2.8e-11 44.1 0.2 5.8e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DnaJ-X PF14308.1 EMC94736.1 - 6.9e-68 227.9 1.5 6.9e-68 227.9 1.0 2.4 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.26 EMC94736.1 - 1.1e-25 89.0 0.5 2.9e-25 87.7 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Ndc1_Nup PF09531.5 EMC94736.1 - 4.8 5.4 4.2 7.3 4.8 2.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DHDPS PF00701.17 EMC94737.1 - 1.7e-37 128.6 0.0 1.9e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 EMC94738.1 - 2e-22 79.4 51.0 2e-22 79.4 35.4 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMC94738.1 - 8e-20 70.5 24.3 1.1e-19 70.0 16.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EMC94739.1 - 3e-17 63.0 0.2 4.4e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC94739.1 - 1.5e-09 37.7 0.1 2.4e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC94739.1 - 2.7e-05 23.7 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family BolA PF01722.13 EMC94740.1 - 4.7e-27 93.7 1.1 5.6e-27 93.5 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein Zip PF02535.17 EMC94742.1 - 3.2e-55 187.3 0.3 3.7e-55 187.1 0.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DAO PF01266.19 EMC94743.1 - 5.9e-46 157.0 0.1 9.2e-46 156.3 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EMC94743.1 - 2.7e-06 27.2 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.1 EMC94743.1 - 3.6e-06 26.9 0.0 8.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC94743.1 - 0.00032 20.6 0.0 0.027 14.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC94743.1 - 0.00073 18.4 0.3 0.0022 16.8 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EMC94743.1 - 0.0034 17.1 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EMC94743.1 - 0.0034 17.4 0.0 0.0079 16.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EMC94743.1 - 0.013 15.2 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 EMC94743.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EMC94743.1 - 0.024 14.7 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMC94743.1 - 0.054 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EMC94743.1 - 0.057 12.2 0.0 7.5 5.2 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 EMC94743.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Glycos_transf_1 PF00534.15 EMC94744.1 - 0.022 14.1 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 MFS_1 PF07690.11 EMC94745.1 - 4e-12 45.5 69.9 3.1e-08 32.7 24.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC94745.1 - 0.0089 15.7 0.2 0.0089 15.7 0.2 3.1 4 0 0 4 4 4 1 MFS_1 like family Methyltransf_18 PF12847.2 EMC94746.1 - 3.3e-15 56.6 0.0 2.3e-14 53.9 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC94746.1 - 1.9e-12 47.0 0.0 3.4e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC94746.1 - 1.5e-11 44.6 0.0 5.2e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC94746.1 - 8.8e-11 41.7 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC94746.1 - 1.1e-10 41.7 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC94746.1 - 4.1e-09 36.8 0.0 9.2e-09 35.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC94746.1 - 4.2e-07 30.0 0.1 7.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC94746.1 - 3.9e-06 26.5 0.0 5.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EMC94746.1 - 8.7e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EMC94746.1 - 9.4e-06 24.8 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EMC94746.1 - 2.5e-05 23.5 0.0 6e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EMC94746.1 - 0.00014 21.2 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.7 EMC94746.1 - 0.00091 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EMC94746.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) 3HCDH_N PF02737.13 EMC94746.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0146 PF03686.8 EMC94746.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) TPMT PF05724.6 EMC94746.1 - 0.0052 16.2 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.6 EMC94746.1 - 0.0075 15.0 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.7 EMC94746.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.12 EMC94746.1 - 0.028 13.4 0.0 0.069 12.1 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.1 EMC94746.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EMC94746.1 - 0.088 12.1 0.1 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Beta-lactamase PF00144.19 EMC94747.1 - 4.6e-24 85.0 5.4 4.6e-24 85.0 3.8 2.4 2 1 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 EMC94747.1 - 0.0035 17.1 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF892 PF05974.7 EMC94748.1 - 0.03 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) AAA_3 PF07726.6 EMC94748.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAD_binding_6 PF08030.7 EMC94749.1 - 4.4e-19 68.9 0.0 1.1e-10 41.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMC94749.1 - 1e-18 67.6 12.4 1e-18 67.6 8.6 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMC94749.1 - 5.3e-15 55.1 0.0 1.8e-14 53.5 0.0 2.0 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMC94749.1 - 0.00046 20.7 0.0 0.88 10.1 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NTR2 PF15458.1 EMC94749.1 - 5.4 6.1 7.9 1.5 8.0 2.5 1.9 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Mg_trans_NIPA PF05653.9 EMC94750.1 - 1.9e-13 50.0 4.1 3.7e-13 49.0 2.9 1.4 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EMC94750.1 - 0.93 9.5 25.0 0.51 10.3 5.2 3.3 2 2 1 3 3 3 0 EamA-like transporter family Fungal_trans_2 PF11951.3 EMC94751.1 - 9.9e-54 182.3 0.0 1.4e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94751.1 - 3.5e-06 26.8 12.4 6.7e-06 25.9 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4311 PF14188.1 EMC94751.1 - 0.34 10.3 0.0 0.56 9.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) PAT1 PF09770.4 EMC94751.1 - 9.2 4.3 8.6 17 3.5 6.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EutQ PF06249.7 EMC94752.1 - 1.4e-09 37.6 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EMC94752.1 - 5.4e-09 35.3 0.0 8e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EMC94752.1 - 0.00086 18.7 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain KduI PF04962.7 EMC94752.1 - 0.015 14.3 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Cupin_6 PF12852.2 EMC94752.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 1 0 1 1 1 0 Cupin PTCB-BRCT PF12738.2 EMC94753.1 - 3.2e-13 49.3 0.0 7.4e-13 48.1 0.0 1.6 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EMC94753.1 - 1.6e-07 31.3 0.0 2.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EMC94753.1 - 0.00025 20.7 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 EMC94753.1 - 0.00083 19.4 0.0 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain Vps55 PF04133.9 EMC94754.1 - 0.054 13.2 0.3 0.063 13.0 0.2 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 ATPase_gene1 PF09527.5 EMC94755.1 - 0.098 12.4 1.5 0.14 12.0 0.2 1.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Malate_synthase PF01274.17 EMC94756.1 - 5.1e-230 763.9 0.0 5.9e-230 763.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase UPF0560 PF10577.4 EMC94757.1 - 0.25 9.5 1.9 0.31 9.2 1.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1687 PF07955.6 EMC94759.1 - 1.4e-16 60.7 0.0 4e-16 59.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EMC94759.1 - 0.13 12.3 0.0 0.81 9.7 0.0 2.3 2 1 0 2 2 2 0 ArsC family EF-hand_6 PF13405.1 EMC94763.1 - 2.4e-10 39.3 0.0 5.5e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMC94763.1 - 1.1e-09 36.8 0.0 8.4e-06 24.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMC94763.1 - 2.3e-09 37.2 0.0 0.00024 21.1 0.0 2.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC94763.1 - 1e-08 34.0 0.1 2.9e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EMC94763.1 - 0.00019 21.3 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC94763.1 - 0.00027 20.4 0.1 0.0043 16.6 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain pair Abhydrolase_8 PF06259.7 EMC94764.1 - 0.051 13.0 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF3121 PF11319.3 EMC94765.1 - 0.088 12.3 0.5 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) MPLKIP PF15502.1 EMC94765.1 - 2.1 9.0 9.2 8.6 7.0 6.4 2.0 1 1 0 1 1 1 0 M-phase-specific PLK1-interacting protein DUF1180 PF06679.7 EMC94767.1 - 0.0034 17.2 1.2 0.01 15.7 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) m04gp34like PF12216.3 EMC94767.1 - 0.011 15.1 0.3 0.02 14.2 0.2 1.3 1 0 0 1 1 1 0 Immune evasion protein Rifin_STEVOR PF02009.11 EMC94767.1 - 0.022 14.4 0.5 0.047 13.3 0.3 1.5 1 0 0 1 1 1 0 Rifin/stevor family Troponin PF00992.15 EMC94767.1 - 5.5 7.0 15.6 1.7 8.7 8.8 1.5 2 0 0 2 2 2 0 Troponin Gp_UL130 PF11668.3 EMC94769.1 - 0.12 11.9 0.1 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Mitofilin PF09731.4 EMC94771.1 - 3.6e-132 441.9 22.3 8.4e-113 378.0 13.0 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Pex14_N PF04695.8 EMC94771.1 - 0.012 15.6 0.4 0.012 15.6 0.3 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_S21 PF01165.15 EMC94771.1 - 0.04 13.3 0.9 0.17 11.3 0.6 2.1 1 0 0 1 1 1 0 Ribosomal protein S21 Hpt PF01627.18 EMC94771.1 - 0.3 11.0 8.7 1.1 9.3 0.0 4.2 3 1 0 3 3 3 0 Hpt domain DUF3373 PF11853.3 EMC94771.1 - 1.3 7.4 6.1 2.1 6.7 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) HXXSHH PF07586.6 EMC94771.1 - 2.4 6.9 7.6 3.5 6.4 4.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1552) Atg14 PF10186.4 EMC94771.1 - 8.8 5.1 14.4 15 4.4 10.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bac_rhodopsin PF01036.13 EMC94772.1 - 4.7e-45 153.6 17.6 6.4e-45 153.1 12.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein RPEL PF02755.10 EMC94772.1 - 1.9e-15 55.6 4.9 1.7e-08 33.5 1.0 2.3 2 0 0 2 2 2 2 RPEL repeat DUF3278 PF11683.3 EMC94772.1 - 0.025 14.5 0.9 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF4131 PF13567.1 EMC94772.1 - 1.8 7.9 6.2 0.95 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_PK PF05891.7 EMC94773.1 - 2.6e-72 242.6 0.0 3e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EMC94773.1 - 6.3e-05 22.7 0.0 9.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC94773.1 - 0.0029 18.1 0.0 0.0062 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_3 PF13738.1 EMC94774.1 - 6.2e-26 91.7 0.0 1.5e-22 80.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC94774.1 - 1.1e-10 40.3 0.0 3.6e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMC94774.1 - 1.6e-09 37.1 0.0 1.5e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMC94774.1 - 3.1e-09 36.7 0.0 7.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC94774.1 - 0.00015 20.8 0.1 0.11 11.3 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC94774.1 - 0.0003 20.5 0.2 0.088 12.5 0.0 3.0 3 2 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC94774.1 - 0.0073 16.2 0.0 0.53 10.1 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.19 EMC94775.1 - 7.3e-15 54.7 0.0 1.1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMC94775.1 - 1.2e-06 28.1 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EMC94775.1 - 0.00041 20.2 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC94775.1 - 0.00061 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC94775.1 - 0.0025 17.9 0.1 0.0045 17.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC94775.1 - 0.0043 16.9 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMC94775.1 - 0.0043 17.0 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.17 EMC94776.1 - 1.9e-55 188.2 0.0 1.1e-54 185.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 SET PF00856.23 EMC94777.1 - 7.9e-09 36.0 0.0 2.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 SET domain Imm2 PF14426.1 EMC94777.1 - 0.069 13.1 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm2 zf-HIT PF04438.11 EMC94777.1 - 0.31 10.7 5.5 0.12 12.0 1.7 1.9 2 0 0 2 2 2 0 HIT zinc finger zf-TFIIB PF13453.1 EMC94779.1 - 0.12 11.5 0.8 0.24 10.6 0.6 1.5 1 1 0 1 1 1 0 Transcription factor zinc-finger zf-FPG_IleRS PF06827.9 EMC94779.1 - 0.61 9.7 5.0 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS YoaP PF14268.1 EMC94780.1 - 0.089 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 YoaP-like HSP90 PF00183.13 EMC94781.1 - 5e-256 850.2 38.0 5.8e-256 850.0 26.4 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EMC94781.1 - 3e-11 43.1 0.3 3e-11 43.1 0.2 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMC94781.1 - 3.8e-10 39.4 0.1 6.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S10 PF00450.17 EMC94781.1 - 0.071 12.2 0.0 0.071 12.2 0.0 2.2 1 1 1 2 2 2 0 Serine carboxypeptidase Tom37_C PF11801.3 EMC94781.1 - 2.1 8.1 9.7 8.5 6.2 3.6 2.9 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF1510 PF07423.6 EMC94781.1 - 2.8 7.2 27.9 0.011 15.0 10.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) PH_9 PF15410.1 EMC94782.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C2H2_4 PF13894.1 EMC94783.1 - 4.4e-09 36.0 12.8 0.0011 19.1 2.2 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC94783.1 - 8.3e-06 25.8 12.9 0.0062 16.8 1.5 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC94783.1 - 0.00022 21.3 15.0 0.028 14.7 0.4 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 EMC94783.1 - 0.34 11.0 6.3 0.098 12.8 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DHH PF01368.15 EMC94784.1 - 3.7e-09 36.3 0.0 5.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 DHH family DUF2422 PF10337.4 EMC94785.1 - 5.6e-86 289.1 17.5 9.2e-85 285.1 6.6 3.1 2 2 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EMC94785.1 - 4.1e-15 56.0 0.0 1.3e-14 54.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EMC94785.1 - 5.7e-12 45.6 18.2 5.7e-12 45.6 12.6 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like adh_short PF00106.20 EMC94789.1 - 1.5e-18 67.2 0.0 2.1e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC94789.1 - 4.9e-06 26.4 0.0 6.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC94789.1 - 0.00012 21.7 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMC94789.1 - 0.031 13.3 0.0 0.11 11.6 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) RRN9 PF10680.4 EMC94790.1 - 4.9e-15 55.0 3.4 4.9e-15 55.0 2.3 2.7 2 1 1 3 3 3 1 RNA polymerase I specific transcription initiation factor DUF566 PF04484.7 EMC94790.1 - 4.6 6.6 10.5 0.11 11.9 2.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF566) IF4E PF01652.13 EMC94791.1 - 9.4e-58 194.3 0.5 1.1e-57 194.1 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1654 PF07867.6 EMC94791.1 - 0.22 10.9 1.1 2.4 7.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1654) DUF619 PF04768.8 EMC94792.1 - 5.8e-46 156.0 0.0 1.1e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EMC94792.1 - 2.2e-29 102.2 0.0 8.2e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EMC94792.1 - 9.2e-25 87.5 0.1 1.9e-24 86.5 0.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EMC94792.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EMC94792.1 - 0.1 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAC PF01849.13 EMC94794.1 - 1.9e-21 75.3 0.1 3.1e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain FAD_binding_3 PF01494.14 EMC94795.1 - 9e-70 235.4 0.1 1.2e-69 235.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC94795.1 - 4e-08 32.5 0.1 0.00029 19.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC94795.1 - 8.1e-06 26.1 0.1 0.024 15.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC94795.1 - 3.1e-05 24.1 0.2 0.00028 20.9 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC94795.1 - 3.2e-05 23.0 0.8 0.00036 19.5 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMC94795.1 - 3.2e-05 23.8 0.1 0.00014 21.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMC94795.1 - 7.8e-05 21.9 0.1 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC94795.1 - 0.00012 22.0 0.0 0.00048 20.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC94795.1 - 0.00017 20.1 0.7 0.00094 17.7 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EMC94795.1 - 0.00022 20.4 0.2 0.0009 18.4 0.1 1.9 1 1 1 2 2 2 1 Thi4 family SE PF08491.5 EMC94795.1 - 0.00099 18.0 0.0 0.063 12.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.19 EMC94795.1 - 0.0013 17.6 0.3 0.0027 16.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EMC94795.1 - 0.011 14.3 0.1 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase PARP PF00644.15 EMC94796.1 - 7.7e-58 195.3 0.1 1.9e-57 194.0 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EMC94796.1 - 2.1e-38 130.9 0.0 3.3e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EMC94796.1 - 1.5e-21 76.1 0.2 3.3e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 WGR domain RNA_pol_Rpb6 PF01192.17 EMC94797.1 - 6e-23 80.3 0.2 6e-23 80.3 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.7 EMC94797.1 - 0.03 14.0 0.1 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2094 PF09867.4 EMC94799.1 - 0.054 13.3 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) UBA PF00627.26 EMC94801.1 - 0.00057 19.6 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.21 EMC94802.1 - 2.1e-10 40.3 11.9 7.4e-05 22.8 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC94802.1 - 6.1e-09 35.6 7.7 0.00015 21.8 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC94802.1 - 7.8e-09 35.3 6.8 7.4e-06 25.9 1.4 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC94802.1 - 0.012 15.7 1.6 0.61 10.2 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC94802.1 - 0.018 15.2 2.0 0.018 15.2 1.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EMC94802.1 - 0.037 13.9 4.1 0.94 9.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EMC94802.1 - 0.69 10.2 3.3 1.7 8.9 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EMC94802.1 - 0.72 9.6 4.8 0.5 10.1 0.2 2.2 2 0 0 2 2 2 0 BED zinc finger PC_rep PF01851.17 EMC94804.1 - 1.5e-45 150.9 15.3 2.2e-10 40.1 0.0 9.7 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMC94804.1 - 1.1e-19 70.5 0.2 2e-12 47.1 0.0 5.1 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 EMC94804.1 - 6.3e-08 32.0 0.0 5.8 7.2 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EMC94804.1 - 1.2e-06 28.7 2.9 0.0025 18.2 0.0 5.6 4 2 2 6 6 6 1 HEAT-like repeat DUF1546 PF07571.8 EMC94804.1 - 0.032 14.3 0.2 6.9 6.8 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1546) TPR_19 PF14559.1 EMC94804.1 - 0.037 14.3 0.4 16 5.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC94804.1 - 0.068 13.3 1.2 0.68 10.1 0.2 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_C10 PF01640.12 EMC94804.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase C10 family HEAT_PBS PF03130.11 EMC94804.1 - 0.17 12.4 5.7 5 7.8 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat mRNA_triPase PF02940.10 EMC94805.1 - 7.7e-40 136.9 0.0 6.9e-39 133.8 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain Spt5-NGN PF03439.8 EMC94806.1 - 6.6e-16 57.8 0.0 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EMC94806.1 - 2.6e-14 53.6 10.7 2.6e-14 53.6 7.4 4.7 2 1 2 4 4 4 2 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 EMC94806.1 - 2.2e-12 47.4 36.6 4.6e-08 33.5 7.6 3.0 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EMC94806.1 - 3e-06 26.7 21.7 0.0036 16.9 0.3 5.5 5 0 0 5 5 5 2 KOW motif TFIIF_alpha PF05793.7 EMC94806.1 - 0.33 9.2 33.8 0.6 8.4 23.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) COesterase PF00135.23 EMC94807.1 - 3.1e-77 260.5 1.4 4.9e-71 240.0 0.6 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC94807.1 - 0.0003 20.4 0.1 0.00097 18.7 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold ZZ PF00569.12 EMC94808.1 - 2e-11 43.2 3.2 3.4e-11 42.5 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EMC94808.1 - 4.7e-08 31.7 2.5 0.0069 15.6 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EMC94808.1 - 1.1e-06 28.0 3.4 0.04 13.7 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EMC94808.1 - 2.8e-06 27.3 3.0 0.00015 21.8 1.3 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC94808.1 - 0.00011 21.7 1.7 0.16 11.6 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC94808.1 - 0.021 14.1 4.7 1 8.7 0.1 3.2 3 0 0 3 3 3 0 EF hand Lipase_chap PF03280.9 EMC94808.1 - 0.054 12.9 1.1 0.11 12.0 0.2 1.8 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein Cupin_1 PF00190.17 EMC94810.1 - 6.9e-09 35.2 0.0 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Cupin MFS_1 PF07690.11 EMC94812.1 - 1.5e-42 145.5 44.6 1.5e-42 145.5 30.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC94812.1 - 4.8e-12 45.2 9.0 4.8e-12 45.2 6.2 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter HlyIII PF03006.15 EMC94812.1 - 0.0002 20.8 6.7 0.0002 20.8 4.6 2.7 1 1 1 3 3 3 1 Haemolysin-III related Abhydrolase_6 PF12697.2 EMC94814.1 - 3e-15 56.7 1.5 6.6e-15 55.6 1.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC94814.1 - 7.7e-13 48.4 0.0 1.6e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94814.1 - 3.6e-06 26.7 0.0 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMC94814.1 - 1e-05 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMC94814.1 - 9.2e-05 22.2 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EMC94814.1 - 0.0096 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Amidase_2 PF01510.20 EMC94814.1 - 0.13 12.2 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase Exo_endo_phos PF03372.18 EMC94815.1 - 6.4e-14 52.4 1.5 9.2e-14 51.9 1.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fez1 PF06818.10 EMC94816.1 - 0.0045 17.0 2.0 0.0045 17.0 1.4 1.8 2 0 0 2 2 2 1 Fez1 AATF-Che1 PF13339.1 EMC94816.1 - 1.4 9.0 8.6 8 6.6 1.0 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor FlxA PF14282.1 EMC94816.1 - 2.9 7.8 9.1 0.24 11.3 2.4 2.1 2 0 0 2 2 2 0 FlxA-like protein Ribosomal_L36 PF00444.13 EMC94817.1 - 6e-18 64.5 9.6 8.4e-18 64.0 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 UQ_con PF00179.21 EMC94819.1 - 2.4e-46 156.6 0.0 2.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC94819.1 - 5.1e-06 26.2 0.0 6.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EMC94819.1 - 0.05 13.2 0.0 0.099 12.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain WD40 PF00400.27 EMC94820.1 - 1.9e-07 30.6 10.1 0.00041 20.1 0.3 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EMC94820.1 - 0.86 9.4 9.7 2.3 8.1 6.8 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EMC94820.1 - 2.3 8.2 9.3 5.3 7.1 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMC94820.1 - 7.1 6.6 8.0 14 5.7 5.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain TRI12 PF06609.8 EMC94822.1 - 2.1e-44 151.7 28.4 2.9e-44 151.2 19.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMC94822.1 - 2.6e-22 79.0 50.2 2.6e-22 79.0 34.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC94822.1 - 6.9e-09 34.7 17.0 6.9e-09 34.7 11.8 3.6 3 1 1 4 4 4 2 Sugar (and other) transporter SRF-TF PF00319.13 EMC94823.1 - 1.4e-23 81.8 0.2 1.9e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EMC94823.1 - 0.015 13.3 0.2 0.019 13.0 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3246 PF11596.3 EMC94823.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4231 PF14015.1 EMC94824.1 - 0.093 12.7 0.5 0.31 11.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) SEN1_N PF12726.2 EMC94826.1 - 4.1e-141 471.4 0.1 5.8e-141 470.9 0.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EMC94826.1 - 5.8e-69 232.2 0.3 5.8e-69 232.2 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EMC94826.1 - 3.9e-63 212.4 0.0 9.3e-63 211.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC94826.1 - 2.9e-11 42.9 0.4 1.1e-10 41.0 0.3 2.1 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 EMC94826.1 - 1.5e-07 31.0 1.4 2e-05 24.0 0.0 3.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EMC94826.1 - 3.2e-07 30.1 1.6 0.00013 21.5 0.2 3.2 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 EMC94826.1 - 0.00061 19.3 0.7 0.28 10.6 0.0 3.5 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase Sugar_tr PF00083.19 EMC94828.1 - 1.3e-82 277.7 15.0 1.5e-82 277.5 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC94828.1 - 2.9e-28 98.6 16.2 4.4e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily fn3_3 PF14686.1 EMC94828.1 - 0.081 13.0 0.1 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II DUF1228 PF06779.9 EMC94828.1 - 0.53 10.3 10.2 1.4 8.9 1.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) SIR2 PF02146.12 EMC94829.1 - 1.5e-29 103.0 0.0 2.7e-29 102.1 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Afi1 PF07792.7 EMC94830.1 - 1.3e-58 197.0 0.0 2.4e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EMC94830.1 - 4.4e-37 126.2 0.0 8e-37 125.4 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EMC94830.1 - 8.8e-09 34.3 0.6 0.12 10.8 0.0 4.0 2 2 2 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 EMC94830.1 - 0.0021 17.4 0.0 0.03 13.6 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) zf-C2H2_4 PF13894.1 EMC94831.1 - 0.0021 18.2 12.8 0.066 13.5 0.0 4.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 EMC94831.1 - 0.16 12.2 3.5 2.4 8.4 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EMC94831.1 - 0.57 10.6 0.1 0.57 10.6 0.1 5.2 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMC94831.1 - 2.1 8.5 4.5 27 5.0 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EMC94831.1 - 3 8.3 11.0 0.85 10.0 1.0 3.7 3 1 0 3 3 3 0 Zinc-finger double domain Methyltransf_23 PF13489.1 EMC94834.1 - 7.6e-15 54.9 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC94834.1 - 4.1e-12 45.9 0.0 5.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC94834.1 - 3e-11 43.8 0.0 4.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC94834.1 - 9.5e-11 41.9 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC94834.1 - 4.4e-10 39.9 0.0 8.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC94834.1 - 1.8e-09 37.9 0.0 3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC94834.1 - 1.1e-07 31.2 0.0 1.9e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMC94834.1 - 0.00017 21.6 0.5 0.00054 19.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMC94834.1 - 0.0027 17.4 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC94834.1 - 0.0038 16.6 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 EMC94834.1 - 0.0039 16.1 0.0 0.0069 15.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EMC94834.1 - 0.016 14.2 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF2249 PF10006.4 EMC94834.1 - 0.043 13.3 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) zf-C2HC5 PF06221.8 EMC94835.1 - 3.2e-23 81.2 3.6 5.5e-23 80.4 2.5 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FAM176 PF14851.1 EMC94835.1 - 0.16 11.6 1.3 0.38 10.4 0.9 1.6 1 0 0 1 1 1 0 FAM176 family zf-ribbon_3 PF13248.1 EMC94835.1 - 2.7 7.3 6.0 5.6 6.3 4.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF2461 PF09365.5 EMC94838.1 - 1.7e-48 164.8 0.2 5e-32 111.0 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical protein (DUF2461) TYW3 PF02676.9 EMC94839.1 - 5.9e-30 103.9 0.0 8e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 ABC_tran PF00005.22 EMC94840.1 - 4e-48 163.2 0.1 8.2e-27 94.1 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMC94840.1 - 7.5e-16 58.9 1.2 0.0012 18.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EMC94840.1 - 7e-13 48.3 0.0 0.00027 20.2 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMC94840.1 - 3.3e-08 34.1 0.0 0.00076 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMC94840.1 - 1e-07 31.3 0.7 0.0061 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EMC94840.1 - 1.3e-06 28.3 0.0 0.0079 16.1 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMC94840.1 - 1.9e-06 27.1 0.0 0.006 15.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Chromo PF00385.19 EMC94840.1 - 2.2e-06 27.2 0.9 4.9e-06 26.1 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 EMC94840.1 - 4.5e-06 27.4 0.0 0.05 14.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EMC94840.1 - 1.4e-05 24.7 0.2 0.032 13.9 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Miro PF08477.8 EMC94840.1 - 2.1e-05 24.9 0.0 0.054 13.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EMC94840.1 - 2.2e-05 23.6 0.0 0.83 8.6 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EMC94840.1 - 3.4e-05 23.9 0.0 0.34 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EMC94840.1 - 6.8e-05 22.4 1.9 0.52 9.6 0.1 4.0 4 0 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EMC94840.1 - 8.4e-05 22.4 0.0 0.67 9.9 0.0 3.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EMC94840.1 - 0.00023 21.1 0.0 0.065 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMC94840.1 - 0.00063 19.8 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EMC94840.1 - 0.00073 19.2 0.0 0.29 10.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EMC94840.1 - 0.00073 18.3 0.2 0.2 10.4 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_33 PF13671.1 EMC94840.1 - 0.0011 18.9 0.0 0.98 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EMC94840.1 - 0.0012 18.7 1.2 0.15 11.8 0.0 3.1 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EMC94840.1 - 0.0013 18.1 0.0 2.3 7.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain HEAT_2 PF13646.1 EMC94840.1 - 0.0041 17.3 2.3 0.034 14.4 0.0 3.3 2 1 1 3 3 2 1 HEAT repeats ATP_bind_1 PF03029.12 EMC94840.1 - 0.0054 16.2 1.1 5.9 6.3 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EMC94840.1 - 0.0072 14.8 0.0 2.8 6.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EMC94840.1 - 0.0077 16.5 1.6 0.32 11.3 0.0 3.2 3 1 0 4 4 3 1 AAA domain Adaptin_N PF01602.15 EMC94840.1 - 0.0078 14.5 0.1 0.013 13.8 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region AAA PF00004.24 EMC94840.1 - 0.011 15.9 0.0 4.5 7.4 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMC94840.1 - 0.011 15.3 0.4 4 6.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.18 EMC94840.1 - 0.014 15.2 0.0 0.34 10.6 0.0 2.7 3 0 0 3 3 2 0 Dynamin family PduV-EutP PF10662.4 EMC94840.1 - 0.022 14.2 0.0 0.71 9.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EMC94840.1 - 0.036 12.9 0.7 0.79 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMC94840.1 - 0.037 13.9 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain CLASP_N PF12348.3 EMC94840.1 - 0.04 13.2 0.0 0.48 9.7 0.0 2.6 3 0 0 3 3 3 0 CLASP N terminal MutS_V PF00488.16 EMC94840.1 - 0.062 12.6 0.3 6.1 6.1 0.0 2.3 2 0 0 2 2 2 0 MutS domain V cobW PF02492.14 EMC94840.1 - 0.075 12.4 0.1 15 4.9 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EMC94840.1 - 0.092 12.4 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase DUF3584 PF12128.3 EMC94840.1 - 0.097 9.9 0.9 2.7 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT PF02985.17 EMC94840.1 - 0.16 12.1 1.3 4.8 7.5 0.0 3.9 5 0 0 5 5 3 0 HEAT repeat FtsK_SpoIIIE PF01580.13 EMC94840.1 - 0.17 11.3 1.6 11 5.4 0.0 3.0 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EMC94840.1 - 0.37 10.7 5.6 1.4 8.8 0.0 3.7 4 0 0 4 4 4 0 AAA ATPase domain Pil1 PF13805.1 EMC94843.1 - 5.9e-155 514.2 0.7 6.9e-155 514.0 0.5 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EMC94843.1 - 0.0067 15.7 2.1 0.011 15.0 0.7 1.8 1 1 0 2 2 2 1 FAM92 protein Glyco_hydro_3 PF00933.16 EMC94844.1 - 2.1e-92 309.2 0.0 3.2e-92 308.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMC94844.1 - 3.8e-51 173.7 0.0 4.1e-50 170.3 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMC94844.1 - 1.1e-17 63.6 0.1 2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Lactamase_B PF00753.22 EMC94845.1 - 1.1e-08 34.9 0.6 3.6e-07 30.0 0.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC94845.1 - 0.0012 18.4 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain adh_short_C2 PF13561.1 EMC94847.1 - 9.2e-25 87.8 0.0 1.3e-24 87.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC94847.1 - 4.4e-24 85.2 0.1 5.9e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC94847.1 - 2.2e-06 27.4 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC94847.1 - 0.0061 16.0 0.1 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3506 PF12014.3 EMC94848.1 - 1.7e-36 124.9 0.0 1e-34 119.2 0.0 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EMC94848.1 - 3.1e-07 29.9 0.0 7.1e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC94848.1 - 0.00019 20.9 0.0 0.0005 19.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain EthD PF07110.6 EMC94850.1 - 0.0022 18.8 0.1 0.0044 17.9 0.1 1.5 1 1 0 1 1 1 1 EthD domain MFS_1 PF07690.11 EMC94852.1 - 1.8e-20 72.9 62.3 2.3e-18 66.0 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MORN_2 PF07661.8 EMC94852.1 - 0.15 12.1 0.1 0.33 11.1 0.1 1.5 1 0 0 1 1 1 0 MORN repeat variant DUF3431 PF11913.3 EMC94853.1 - 2.4e-82 275.7 0.0 3e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Peptidase_C50 PF03568.12 EMC94854.1 - 8.2e-91 304.5 0.0 6.7e-86 288.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase family C50 RRM_1 PF00076.17 EMC94854.1 - 1.8e-19 69.1 0.0 4.2e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC94854.1 - 2.7e-15 56.1 0.0 6.5e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC94854.1 - 3.6e-10 39.5 0.0 1.4e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.1 EMC94854.1 - 0.00088 19.1 0.2 0.00088 19.1 0.1 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat PTCB-BRCT PF12738.2 EMC94855.1 - 8.9e-05 22.2 0.3 0.00055 19.7 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EMC94855.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain ANTH PF07651.11 EMC94855.1 - 0.075 11.7 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 ANTH domain EF-hand_8 PF13833.1 EMC94856.1 - 0.15 11.6 0.5 4.3 7.0 0.3 2.4 1 1 0 1 1 1 0 EF-hand domain pair DAHP_synth_2 PF01474.11 EMC94857.1 - 1.9e-193 642.7 0.0 2.2e-193 642.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Amidase PF01425.16 EMC94858.1 - 1.7e-93 313.8 0.0 2e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 Amidase SSrecog PF03531.9 EMC94859.1 - 3.5e-71 239.0 0.8 1.1e-69 234.2 0.6 2.6 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EMC94859.1 - 2.2e-27 94.8 0.0 2.5e-26 91.4 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SRP-alpha_N PF04086.8 EMC94861.1 - 2.1e-61 207.7 6.8 5.4e-60 203.1 4.7 2.1 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EMC94861.1 - 1.5e-43 148.5 0.1 5.4e-43 146.7 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EMC94861.1 - 1.6e-06 28.1 0.1 3.7e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EMC94861.1 - 0.0004 19.2 0.2 0.0011 17.8 0.1 1.8 1 1 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 EMC94861.1 - 0.0039 16.7 0.1 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EMC94861.1 - 0.0055 16.1 0.1 0.012 14.9 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EMC94861.1 - 0.01 15.5 0.1 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EMC94861.1 - 0.036 13.4 0.0 0.088 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMC94861.1 - 0.047 13.6 0.1 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 EMC94861.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.1 EMC94861.1 - 0.14 12.1 0.1 1.2 9.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain YIF1 PF03878.10 EMC94862.1 - 3e-76 255.7 2.3 3.7e-76 255.4 1.6 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EMC94862.1 - 0.0018 17.8 5.8 0.0018 17.8 4.0 1.7 2 0 0 2 2 2 1 Yip1 domain Peptidase_A22B PF04258.8 EMC94863.1 - 9e-57 192.7 0.0 3.3e-56 190.9 0.0 1.8 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EMC94863.1 - 7.3e-07 28.6 0.6 7.3e-07 28.6 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) Pox_A14 PF05767.7 EMC94863.1 - 0.013 15.4 0.7 4.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 HET PF06985.6 EMC94864.1 - 2.3e-19 69.9 0.1 2.7e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EMC94867.1 - 7.4e-12 45.2 0.0 2.8e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMC94867.1 - 3.7e-07 30.3 0.0 8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC94867.1 - 0.00029 21.6 0.0 0.0011 19.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC94867.1 - 0.00046 19.6 0.1 0.01 15.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC94867.1 - 0.001 19.0 0.0 0.0051 16.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 EMC94867.1 - 0.0017 17.4 0.0 0.98 8.3 0.0 2.1 2 0 0 2 2 2 2 KAP family P-loop domain AAA_18 PF13238.1 EMC94867.1 - 0.0029 17.9 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMC94867.1 - 0.0033 17.6 0.0 0.021 15.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EMC94867.1 - 0.015 15.6 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CobU PF02283.11 EMC94867.1 - 0.02 14.3 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RNA_helicase PF00910.17 EMC94867.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EMC94867.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMC94867.1 - 0.078 12.7 0.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain MMR_HSR1 PF01926.18 EMC94867.1 - 0.12 12.3 0.0 0.54 10.2 0.0 2.1 2 2 0 2 2 2 0 50S ribosome-binding GTPase Sigma54_activat PF00158.21 EMC94867.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EMC94867.1 - 0.14 11.6 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1772 PF08592.6 EMC94868.1 - 1.6e-13 50.5 2.4 1.6e-13 50.5 1.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) AMP-binding PF00501.23 EMC94869.1 - 1.6e-57 194.7 0.0 2.2e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94869.1 - 8.4e-05 23.4 0.0 0.00022 22.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EMC94870.1 - 0.0078 16.0 1.4 14 5.7 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4160 PF13711.1 EMC94870.1 - 0.14 11.9 0.5 0.41 10.5 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Methyltransf_2 PF00891.13 EMC94871.1 - 2.3e-29 102.2 0.0 3.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EMC94871.1 - 0.00019 21.2 2.3 0.0014 18.3 0.1 2.6 2 1 0 2 2 2 1 Dimerisation domain Methyltransf_31 PF13847.1 EMC94871.1 - 0.15 11.6 0.0 0.7 9.4 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Tom37_C PF11801.3 EMC94872.1 - 1.7e-28 99.5 0.0 3e-28 98.7 0.0 1.4 1 1 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EMC94872.1 - 5.6e-12 45.7 0.0 3.4e-11 43.2 0.0 2.3 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EMC94872.1 - 1.3e-06 28.2 0.1 2.9e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC94872.1 - 2e-06 28.2 0.2 1.9e-05 25.0 0.0 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC94872.1 - 6.2e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_C54 PF03416.14 EMC94872.1 - 0.037 13.1 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C54 Methyltransf_18 PF12847.2 EMC94874.1 - 1.3e-06 28.9 0.0 1.5e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC94874.1 - 3.6e-06 26.6 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC94874.1 - 2.1e-05 24.9 0.0 2.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC94874.1 - 5.8e-05 22.5 0.0 6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMC94874.1 - 7e-05 22.8 0.0 8.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC94874.1 - 0.00022 21.0 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC94874.1 - 0.0025 18.2 0.0 0.0031 17.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC94874.1 - 0.0027 16.8 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EMC94874.1 - 0.0089 16.3 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMC94874.1 - 0.0092 15.2 0.0 0.0092 15.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 EMC94874.1 - 0.011 14.8 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_M17 PF00883.16 EMC94874.1 - 0.013 14.3 0.0 0.014 14.2 0.0 1.0 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain FtsJ PF01728.14 EMC94874.1 - 0.031 14.2 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 EMC94874.1 - 0.042 12.8 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EMC94874.1 - 0.053 12.6 0.0 0.06 12.4 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EMC94874.1 - 0.053 12.4 0.0 0.059 12.3 0.0 1.0 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 EMC94874.1 - 0.071 12.6 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EMC94874.1 - 0.13 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain ANTH PF07651.11 EMC94875.1 - 1.5e-59 200.9 0.1 2.3e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EMC94875.1 - 0.00039 20.2 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.15 EMC94876.1 - 7e-108 360.3 0.0 9.3e-108 359.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EMC94876.1 - 6.7e-07 29.0 0.3 0.00063 19.3 0.1 2.3 1 1 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EMC94876.1 - 0.0035 16.5 0.3 0.015 14.4 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) Aldedh PF00171.17 EMC94877.1 - 6.6e-185 614.8 1.0 7.5e-185 614.6 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMC94877.1 - 0.0048 16.1 0.0 0.0096 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) TAXi_C PF14541.1 EMC94877.1 - 0.064 12.8 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Abhydrolase_6 PF12697.2 EMC94878.1 - 1.1e-36 126.8 0.0 1.3e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94878.1 - 1.2e-23 83.8 0.0 4.4e-14 52.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC94878.1 - 6.1e-20 71.4 0.2 3.7e-19 68.9 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC94878.1 - 8.4e-08 31.9 0.0 2.4e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EMC94878.1 - 0.0011 18.3 0.1 0.0064 15.9 0.1 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EMC94878.1 - 0.0015 17.0 0.3 0.018 13.5 0.1 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EMC94878.1 - 0.0019 17.4 0.0 0.017 14.3 0.0 2.3 2 2 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EMC94878.1 - 0.0062 16.4 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein PhoPQ_related PF10142.4 EMC94878.1 - 0.016 13.7 0.0 0.027 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Ndr PF03096.9 EMC94878.1 - 0.017 13.6 0.0 0.58 8.5 0.0 2.1 1 1 0 1 1 1 0 Ndr family Esterase PF00756.15 EMC94878.1 - 0.018 14.4 0.5 0.076 12.4 0.2 2.2 1 1 0 2 2 2 0 Putative esterase DLH PF01738.13 EMC94878.1 - 0.046 13.0 0.1 0.42 9.8 0.0 2.3 2 1 1 3 3 3 0 Dienelactone hydrolase family FSH1 PF03959.8 EMC94878.1 - 0.14 11.6 0.0 0.85 9.0 0.0 2.1 2 1 0 3 3 3 0 Serine hydrolase (FSH1) Lipase_2 PF01674.13 EMC94878.1 - 0.16 11.2 0.0 0.35 10.1 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 2) Methyltransf_23 PF13489.1 EMC94879.1 - 7.6e-20 71.2 0.0 1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC94879.1 - 1.4e-16 60.4 0.0 7e-16 58.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC94879.1 - 2e-15 57.0 0.0 4.7e-15 55.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC94879.1 - 6.2e-14 52.2 0.0 1.3e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC94879.1 - 2.5e-12 47.3 0.0 8e-12 45.7 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC94879.1 - 1.7e-07 31.5 0.0 3.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC94879.1 - 4.2e-07 29.3 0.0 3e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMC94879.1 - 1.4e-05 24.5 0.0 2.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMC94879.1 - 2.6e-05 24.2 0.1 9.9e-05 22.3 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain NodS PF05401.6 EMC94879.1 - 9.1e-05 21.9 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EMC94879.1 - 0.00017 20.7 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 EMC94879.1 - 0.00022 20.1 0.0 0.00049 19.0 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase PrmA PF06325.8 EMC94879.1 - 0.00098 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 EMC94879.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 EMC94879.1 - 0.0022 17.4 0.0 0.0048 16.3 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EMC94879.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EMC94879.1 - 0.041 13.0 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.6 EMC94879.1 - 0.042 12.5 0.0 0.056 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FmrO PF07091.6 EMC94879.1 - 0.044 12.7 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EMC94879.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3321 PF11968.3 EMC94879.1 - 0.16 11.5 0.0 16 5.0 0.0 2.8 3 0 0 3 3 3 0 Putative methyltransferase (DUF3321) DUF1772 PF08592.6 EMC94883.1 - 6.1e-21 74.6 0.4 7.3e-21 74.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Lactamase_B PF00753.22 EMC94885.1 - 0.00021 21.0 0.3 0.00059 19.5 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC94885.1 - 0.00048 19.7 0.0 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Attacin_C PF03769.10 EMC94885.1 - 0.0036 17.4 0.0 0.01 15.9 0.0 1.7 2 0 0 2 2 2 1 Attacin, C-terminal region Pkinase PF00069.20 EMC94886.1 - 1.3e-74 250.6 0.0 1.5e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC94886.1 - 4.7e-37 127.4 0.0 6.4e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC94886.1 - 0.0057 15.6 0.0 0.046 12.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC94886.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EMC94886.1 - 0.022 13.7 0.0 0.06 12.4 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EMC94886.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CBP4 PF07960.6 EMC94887.1 - 4.5e-36 123.2 2.2 5e-36 123.1 1.5 1.1 1 0 0 1 1 1 1 CBP4 Seryl_tRNA_N PF02403.17 EMC94887.1 - 0.9 9.5 6.2 2 8.4 4.3 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2852 PF11014.3 EMC94887.1 - 2.6 8.0 8.1 3 7.8 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) ERCC4 PF02732.10 EMC94889.1 - 7.5e-24 84.1 0.0 1.5e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_2 PF12826.2 EMC94889.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif PIG-U PF06728.8 EMC94890.1 - 6e-107 357.8 20.8 7.1e-107 357.5 14.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 EMC94891.1 - 2.9e-113 377.8 0.0 2.9e-113 377.8 0.0 1.5 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EMC94891.1 - 2.6e-06 27.4 0.0 2.7e-05 24.2 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Acetyltransf_1 PF00583.19 EMC94892.1 - 1e-12 47.8 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC94892.1 - 2.2e-06 27.7 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC94892.1 - 0.00014 21.9 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC94892.1 - 0.00029 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EMC94892.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_1 PF13232.1 EMC94893.1 - 3e-13 49.7 0.1 5.1e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMC94893.1 - 3.9e-13 48.9 0.1 6.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) GNAT_acetyltran PF12746.2 EMC94893.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase tRNA-synt_1b PF00579.20 EMC94894.1 - 3.3e-70 236.4 0.0 4.1e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ADH_zinc_N PF00107.21 EMC94895.1 - 3e-21 75.3 1.2 5.3e-21 74.5 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC94895.1 - 3.3e-10 40.9 0.5 6.7e-10 39.9 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC94895.1 - 0.00045 19.9 0.3 0.0059 16.3 0.0 2.5 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EMC94895.1 - 0.11 12.5 1.9 1 9.3 0.5 2.5 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HTH_23 PF13384.1 EMC94896.1 - 0.13 11.9 0.1 0.98 9.1 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain DUF3678 PF12435.3 EMC94897.1 - 0.097 12.2 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) HopW1-1 PF15457.1 EMC94898.1 - 0.011 14.7 0.2 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Med9 PF07544.8 EMC94898.1 - 0.09 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 P_C PF06640.6 EMC94900.1 - 0.24 11.3 2.5 0.26 11.2 1.7 1.1 1 0 0 1 1 1 0 P protein C-terminus zf-C2H2 PF00096.21 EMC94901.1 - 2.5e-30 102.9 46.4 0.0002 21.5 0.2 10.9 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC94901.1 - 5.5e-27 92.0 34.6 0.0031 17.7 0.1 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC94901.1 - 1e-15 57.1 45.6 9.6e-07 28.8 0.1 11.1 10 1 0 10 10 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC94901.1 - 5.9e-09 35.8 19.6 0.73 10.0 0.0 9.0 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC94901.1 - 0.0035 17.4 32.0 0.25 11.6 0.2 8.2 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-met PF12874.2 EMC94901.1 - 0.045 13.9 16.8 40 4.5 0.2 8.5 10 0 0 10 10 10 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC94901.1 - 0.057 13.5 38.0 1.1 9.4 0.1 8.2 7 2 2 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.7 EMC94901.1 - 0.49 10.0 15.9 2 8.1 0.1 5.8 3 2 2 5 5 5 0 Ogr/Delta-like zinc finger CHORD PF04968.7 EMC94901.1 - 1.7 8.9 17.9 3 8.1 0.5 5.5 5 2 1 6 6 6 0 CHORD Hint_2 PF13403.1 EMC94902.1 - 0.013 15.3 0.1 0.019 14.9 0.1 1.3 1 1 0 1 1 1 0 Hint domain PMI_typeI PF01238.16 EMC94904.1 - 3.9e-69 233.4 0.0 4.2e-68 230.0 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EMC94904.1 - 0.00042 19.7 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EMC94904.1 - 0.082 12.6 0.0 0.78 9.4 0.0 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF663 PF04950.7 EMC94905.1 - 2e-94 315.9 0.0 2.6e-94 315.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMC94905.1 - 4.5e-19 67.7 0.0 1.5e-18 66.1 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain HMGL-like PF00682.14 EMC94906.1 - 3.4e-28 98.9 0.0 4.3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 HMGL-like DUF362 PF04015.7 EMC94906.1 - 0.051 13.0 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Retinal PF15449.1 EMC94906.1 - 0.96 7.0 10.9 1.1 6.8 7.5 1.0 1 0 0 1 1 1 0 Retinal protein AAA_17 PF13207.1 EMC94907.1 - 1.6e-05 25.7 0.0 5e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC94907.1 - 6.6e-05 23.2 0.0 0.00028 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EMC94907.1 - 0.0013 18.3 0.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 EMC94907.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EMC94907.1 - 0.0051 16.6 0.0 0.05 13.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EMC94907.1 - 0.11 11.5 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin DUF2427 PF10348.4 EMC94910.1 - 0.0028 17.2 11.8 0.0028 17.2 8.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) Steroid_dh PF02544.11 EMC94911.1 - 6.1e-33 113.7 0.7 8.3e-33 113.2 0.5 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EMC94911.1 - 8.1e-05 22.6 0.5 0.00018 21.5 0.4 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EMC94911.1 - 0.003 16.8 0.3 0.0044 16.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) An_peroxidase PF03098.10 EMC94912.1 - 2.5e-94 316.5 0.0 3.4e-92 309.5 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EMC94912.1 - 1.4e-05 23.8 0.0 3.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_A_bac PF01000.21 EMC94913.1 - 1.6e-29 102.3 0.0 2.9e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMC94913.1 - 1.7e-12 46.2 0.0 2.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RCC1 PF00415.13 EMC94914.1 - 1.2e-14 54.2 2.4 1.5e-05 25.0 0.0 3.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC94914.1 - 5.5e-09 35.3 5.1 0.0007 19.1 0.1 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat NAD_binding_8 PF13450.1 EMC94915.1 - 1.2e-16 60.4 0.0 2.8e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMC94915.1 - 4.1e-06 26.1 0.1 2.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMC94915.1 - 9.1e-06 24.8 0.0 2.6e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC94915.1 - 2.5e-05 23.3 0.0 6.3e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC94915.1 - 0.00011 22.3 0.2 0.00038 20.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC94915.1 - 0.00041 20.2 0.0 0.00066 19.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC94915.1 - 0.00097 19.4 0.0 0.0036 17.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC94915.1 - 0.0021 16.5 0.0 0.0033 15.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EMC94915.1 - 0.0056 15.7 0.0 0.0098 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EMC94915.1 - 0.014 14.3 0.1 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EMC94915.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC94915.1 - 0.038 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding IlvN PF07991.7 EMC94915.1 - 0.079 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain V-SNARE PF05008.10 EMC94916.1 - 1e-19 70.4 4.3 1e-19 70.4 3.0 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EMC94916.1 - 1.6e-16 60.0 5.0 1.6e-16 60.0 3.5 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMC94916.1 - 0.014 15.0 2.7 0.074 12.7 0.2 2.4 2 0 0 2 2 2 0 Sec20 Fusion_gly PF00523.13 EMC94916.1 - 0.025 12.6 1.4 0.11 10.5 0.1 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 RRF PF01765.14 EMC94916.1 - 0.037 13.5 0.7 0.06 12.8 0.5 1.4 1 0 0 1 1 1 0 Ribosome recycling factor OppC_N PF12911.2 EMC94916.1 - 0.053 12.8 3.5 0.095 12.0 2.4 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Spectrin PF00435.16 EMC94916.1 - 0.26 11.6 6.2 0.33 11.2 1.6 2.6 1 1 2 3 3 3 0 Spectrin repeat DUF912 PF06024.7 EMC94916.1 - 0.27 11.3 1.5 0.34 10.9 0.0 1.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Synaptobrevin PF00957.16 EMC94916.1 - 0.31 10.6 3.7 0.23 11.0 1.0 2.1 2 1 0 2 2 2 0 Synaptobrevin DUF1741 PF08427.5 EMC94917.1 - 6.8e-66 222.1 0.1 1.3e-65 221.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) zf-ZPR1 PF03367.8 EMC94917.1 - 0.057 12.5 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 ZPR1 zinc-finger domain DUF726 PF05277.7 EMC94918.1 - 6.8e-114 380.3 3.5 9.7e-114 379.8 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EMC94918.1 - 0.0005 20.0 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMC94918.1 - 0.00062 20.0 0.0 0.00062 20.0 0.0 2.8 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_5 PF12695.2 EMC94918.1 - 0.0037 17.0 0.8 0.013 15.2 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 EMC94918.1 - 0.0073 16.0 0.2 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Cutinase Abhydrolase_1 PF00561.15 EMC94918.1 - 0.035 13.6 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF706 PF05153.10 EMC94919.1 - 1.9e-123 410.7 0.6 1.9e-123 410.7 0.4 1.3 2 0 0 2 2 2 1 Family of unknown function (DUF706) Exonuc_X-T_C PF08411.5 EMC94919.1 - 0.0059 15.6 2.2 0.0085 15.1 1.5 1.2 1 0 0 1 1 1 1 Exonuclease C-terminal HD PF01966.17 EMC94919.1 - 0.034 14.1 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 HD domain adh_short PF00106.20 EMC94921.1 - 1.5e-34 119.3 0.2 2.4e-34 118.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC94921.1 - 1.1e-20 74.4 0.0 1.3e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC94921.1 - 6.5e-15 55.2 0.3 1e-14 54.6 0.2 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMC94921.1 - 2.5e-05 23.9 0.1 4.9e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMC94921.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC94921.1 - 0.0028 17.7 0.2 0.04 13.9 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding Glyco_transf_5 PF08323.6 EMC94921.1 - 0.016 14.6 0.0 0.082 12.3 0.0 2.0 2 1 0 2 2 2 0 Starch synthase catalytic domain 2-Hacid_dh_C PF02826.14 EMC94921.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CW_binding_2 PF04122.7 EMC94921.1 - 0.081 13.1 0.1 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Ribosomal_L21e PF01157.13 EMC94921.1 - 0.15 11.8 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L21e NmrA PF05368.8 EMC94921.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EMC94921.1 - 0.18 10.6 0.8 0.26 10.1 0.1 1.7 2 1 0 2 2 2 0 RmlD substrate binding domain ADH_N PF08240.7 EMC94922.1 - 5.9e-29 100.0 0.9 7.7e-29 99.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC94922.1 - 5e-19 68.1 0.2 9.6e-19 67.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMC94922.1 - 0.026 13.9 0.1 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EMC94922.1 - 0.028 15.0 0.4 0.095 13.2 0.3 2.1 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_2 PF00890.19 EMC94922.1 - 0.034 12.9 0.4 0.046 12.5 0.3 1.1 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 EMC94922.1 - 0.064 12.8 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EMC94922.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EMC94922.1 - 0.075 12.6 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMC94922.1 - 0.15 10.5 2.0 0.21 10.0 1.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Med3 PF11593.3 EMC94923.1 - 9.5 5.3 13.1 17 4.5 9.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aldo_ket_red PF00248.16 EMC94925.1 - 8.8e-51 172.3 0.0 1.1e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CENP-S PF15630.1 EMC94926.1 - 6.6e-28 96.7 0.0 8.2e-28 96.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EMC94926.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF815 PF05673.8 EMC94926.1 - 0.081 11.8 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Myotub-related PF06602.9 EMC94927.1 - 1.8e-107 359.1 0.0 2.5e-107 358.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EMC94927.1 - 0.026 14.7 0.1 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family HECT PF00632.20 EMC94928.1 - 5.3e-97 324.7 0.2 9.1e-97 324.0 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 EMC94928.1 - 5.2e-89 298.6 0.0 5.2e-89 298.6 0.0 3.8 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EMC94928.1 - 3.6e-63 213.8 0.1 3.6e-63 213.8 0.1 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EMC94928.1 - 4e-26 91.0 13.1 4e-26 91.0 9.1 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF4414) PXB PF12828.2 EMC94929.1 - 0.13 11.8 0.1 0.38 10.3 0.1 1.7 1 0 0 1 1 1 0 PX-associated DUF3499 PF12005.3 EMC94929.1 - 0.7 10.0 3.9 0.22 11.7 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) HpcH_HpaI PF03328.9 EMC94930.1 - 5.7e-38 130.0 0.0 1.8e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EMC94930.1 - 8e-13 47.9 0.0 1.1e-06 27.7 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF3755 PF12579.3 EMC94930.1 - 0.051 12.9 0.3 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) DUF846 PF05832.7 EMC94931.1 - 1.1e-51 174.3 6.2 1.3e-51 174.0 4.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.1 EMC94931.1 - 0.24 11.4 11.3 1.7 8.7 1.4 2.1 2 0 0 2 2 2 0 YwiC-like protein HXXEE PF13787.1 EMC94931.1 - 0.5 10.7 6.2 0.32 11.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif ABC2_membrane_3 PF12698.2 EMC94931.1 - 2 7.3 9.5 0.08 11.9 0.9 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein AMP-binding PF00501.23 EMC94932.1 - 8.4e-81 271.4 0.1 1.1e-80 271.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC94932.1 - 2.8e-11 44.1 0.0 1.1e-10 42.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CBM_1 PF00734.13 EMC94934.1 - 1.3e-12 47.0 15.5 4.5e-12 45.4 10.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DPBB_1 PF03330.13 EMC94934.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 2.8 3 1 0 3 3 3 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Myticin-prepro PF10690.4 EMC94934.1 - 0.2 11.6 5.0 0.13 12.2 1.5 2.1 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel ETS_PEA3_N PF04621.8 EMC94934.1 - 1.1 8.3 4.4 1.5 8.0 3.0 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain KIAA1328 PF15369.1 EMC94934.1 - 1.6 8.5 4.0 1.9 8.2 2.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Med3 PF11593.3 EMC94934.1 - 5.9 6.0 15.3 8.6 5.4 10.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2406 PF10295.4 EMC94936.1 - 1.8e-18 66.7 0.1 6e-18 65.1 0.1 1.9 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.5 EMC94937.1 - 3.7e-13 49.1 7.9 5.4e-13 48.6 5.5 1.3 1 0 0 1 1 1 1 VMA21-like domain DUF1328 PF07043.8 EMC94937.1 - 3.7 7.5 6.8 0.46 10.4 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) SNF2_N PF00176.18 EMC94938.1 - 1.3e-62 211.2 0.0 1.9e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC94938.1 - 2.8e-13 49.5 0.0 1.1e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC94938.1 - 2.5e-06 27.4 0.0 6.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA PF00627.26 EMC94938.1 - 0.0062 16.3 0.1 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DEAD_2 PF06733.10 EMC94938.1 - 0.0066 15.8 0.0 0.3 10.4 0.0 3.2 4 0 0 4 4 4 1 DEAD_2 AAA_22 PF13401.1 EMC94938.1 - 0.019 15.1 0.0 0.093 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rab5ip PF07019.7 EMC94939.1 - 6.7e-22 77.4 5.1 8.1e-22 77.1 3.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Nro1 PF12753.2 EMC94940.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF4398 PF14346.1 EMC94940.1 - 0.4 10.7 7.0 0.82 9.7 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) Vezatin PF12632.2 EMC94941.1 - 1.3e-42 145.6 0.0 2.2e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes ZYG-11_interact PF05884.7 EMC94941.1 - 0.015 14.3 0.7 0.036 13.1 0.5 1.6 1 0 0 1 1 1 0 Interactor of ZYG-11 PTN_MK_C PF01091.13 EMC94941.1 - 0.13 12.2 0.4 0.31 11.0 0.3 1.6 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, C-terminal domain Polysacc_synt_C PF14667.1 EMC94941.1 - 0.2 11.4 4.4 0.36 10.6 3.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Sec20 PF03908.8 EMC94942.1 - 3.3e-15 55.5 0.4 3.3e-15 55.5 0.3 3.6 4 1 1 5 5 5 1 Sec20 TINF2_N PF14973.1 EMC94942.1 - 0.62 10.1 3.7 4.1 7.5 0.7 2.7 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus ISG65-75 PF11727.3 EMC94942.1 - 3.5 6.5 13.0 0.27 10.2 5.2 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein Sec63 PF02889.11 EMC94943.1 - 4.2e-195 647.1 2.9 6.5e-109 363.9 0.0 3.2 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 EMC94943.1 - 1.3e-47 161.4 0.5 6e-30 103.9 0.0 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC94943.1 - 1.2e-11 44.3 0.0 7.7e-10 38.4 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC94943.1 - 2.3e-09 37.3 0.0 3.1e-07 30.3 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMC94943.1 - 0.00028 21.0 0.1 0.019 15.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain HALZ PF02183.13 EMC94944.1 - 3.2 7.5 7.4 20 4.9 0.5 3.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper PWWP PF00855.12 EMC94945.1 - 7.9e-18 64.4 0.0 7.9e-18 64.4 0.0 2.7 2 0 0 2 2 2 1 PWWP domain Rep_Org_C PF06926.6 EMC94949.1 - 0.0094 16.0 0.1 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative replisome organiser protein C-terminus Phos_pyr_kin PF08543.7 EMC94950.1 - 7.8e-10 38.3 0.0 2.9e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EMC94950.1 - 7.2e-07 28.6 0.4 4.4e-06 26.0 0.3 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PCNA_N PF00705.13 EMC94951.1 - 8.4e-54 180.4 5.8 8.4e-54 180.4 4.0 1.9 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EMC94951.1 - 1.3e-52 177.1 0.1 6.2e-52 174.8 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EMC94951.1 - 1.3e-10 40.8 0.2 1.6e-10 40.5 0.1 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EMC94951.1 - 0.00033 19.7 0.6 0.0023 16.9 0.1 2.1 2 1 0 2 2 2 1 Hus1-like protein GTP_EFTU PF00009.22 EMC94952.1 - 2e-42 144.7 0.0 3e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMC94952.1 - 3.5e-25 87.8 0.0 7.7e-25 86.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMC94952.1 - 1.8e-16 59.8 0.0 4.9e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMC94952.1 - 1.1e-10 41.4 0.1 3.8e-10 39.7 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMC94952.1 - 8.1e-07 28.8 0.0 2.6e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 EMC94952.1 - 0.00018 22.0 0.0 0.00053 20.4 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC94952.1 - 0.0003 20.7 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMC94952.1 - 0.071 12.3 0.1 0.68 9.1 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.18 EMC94953.1 - 3.3e-96 321.2 0.3 5.8e-96 320.5 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC94953.1 - 1.7e-45 153.4 1.3 1.7e-45 153.4 0.9 2.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMC94953.1 - 7.2e-05 22.3 4.6 0.00014 21.4 1.9 2.2 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EMC94953.1 - 0.0016 18.0 4.4 0.046 13.3 0.3 3.0 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 EMC94953.1 - 0.012 14.0 0.7 0.026 12.9 0.2 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DUF202 PF02656.10 EMC94954.1 - 6.2e-06 26.3 1.7 6.2e-06 26.3 1.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cation_efflux PF01545.16 EMC94955.1 - 1.4e-77 260.5 0.1 2.6e-77 259.7 0.1 1.4 1 1 0 1 1 1 1 Cation efflux family CFEM PF05730.6 EMC94958.1 - 2e-09 37.1 3.9 2.2e-09 37.0 2.7 1.0 1 0 0 1 1 1 1 CFEM domain zf-MYND PF01753.13 EMC94960.1 - 1.6e-12 47.0 72.2 0.0014 18.4 4.9 7.1 6 1 0 6 6 6 6 MYND finger Vps39_2 PF10367.4 EMC94962.1 - 1.5e-31 108.7 0.0 4.4e-31 107.2 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EMC94962.1 - 1.5e-28 98.9 0.0 9.9e-28 96.3 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EMC94962.1 - 2e-15 56.9 0.0 1.2e-14 54.3 0.0 2.0 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 EMC94962.1 - 0.00037 20.1 0.3 0.0014 18.2 0.2 1.9 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_1 PF00515.23 EMC94962.1 - 2.1 8.0 4.6 8.2 6.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat LSM PF01423.17 EMC94963.1 - 2.1e-13 49.6 0.2 3e-13 49.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain HbrB PF08539.6 EMC94966.1 - 2.4e-51 173.7 0.0 3.5e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Pkinase PF00069.20 EMC94968.1 - 3.3e-70 236.2 0.0 4.2e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC94968.1 - 4.8e-35 120.8 0.1 9.8e-35 119.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC94968.1 - 7.3e-05 21.8 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EMC94968.1 - 0.00051 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EMC94968.1 - 0.0068 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 EMC94969.1 - 1.3e-24 86.2 0.0 1.5e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC94969.1 - 1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC94969.1 - 0.0095 15.8 0.6 0.012 15.4 0.4 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EMC94969.1 - 0.023 14.3 0.4 0.071 12.7 0.1 1.8 1 1 1 2 2 2 0 UEV domain DUF3328 PF11807.3 EMC94970.1 - 4.7e-12 46.0 9.5 1.2e-11 44.6 6.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Ank_2 PF12796.2 EMC94971.1 - 2.1e-46 156.1 10.9 5.9e-18 65.0 0.2 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC94971.1 - 2.3e-40 134.4 14.9 1.9e-07 30.5 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 EMC94971.1 - 2e-31 104.9 2.6 2e-05 24.4 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EMC94971.1 - 6.6e-30 102.9 9.2 2.4e-06 27.9 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC94971.1 - 1.9e-23 81.9 11.8 2.5e-05 24.3 0.1 6.1 2 1 4 6 6 6 6 Ankyrin repeats (many copies) FA PF08736.6 EMC94971.1 - 0.00041 20.0 0.1 0.21 11.4 0.0 3.1 3 0 0 3 3 3 1 FERM adjacent (FA) Sec1 PF00995.18 EMC94972.1 - 2.4e-91 307.0 0.0 2.8e-91 306.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Myosin_head PF00063.16 EMC94973.1 - 7.6e-235 781.1 6.4 1.1e-234 780.5 4.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EMC94973.1 - 1.8e-44 151.4 0.0 3.2e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EMC94973.1 - 1.7e-12 46.5 0.1 3.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC94973.1 - 5.3e-10 38.7 0.1 1.1e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC94973.1 - 3.1e-09 36.1 0.0 1.2e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EMC94973.1 - 0.0057 16.7 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain IQ PF00612.22 EMC94973.1 - 0.0086 15.6 6.3 0.48 10.2 0.7 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif SH3_3 PF08239.6 EMC94973.1 - 0.011 15.8 0.1 0.03 14.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Zeta_toxin PF06414.7 EMC94973.1 - 0.022 13.8 0.0 0.053 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EMC94973.1 - 0.038 13.3 1.0 3.6 6.8 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 EMC94973.1 - 0.056 14.2 0.0 0.22 12.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EMC94973.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EMC94973.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GFA PF04828.9 EMC94974.1 - 1.1e-17 63.6 0.2 1.5e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EMC94974.1 - 0.38 10.3 6.0 1.5 8.3 0.1 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PX PF00787.19 EMC94976.1 - 4.4e-18 65.1 0.0 5.9e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 PX domain tRNA-synt_His PF13393.1 EMC94977.1 - 6.4e-39 133.8 0.0 5.9e-37 127.3 0.0 2.5 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EMC94977.1 - 2.3e-17 63.1 0.0 3.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC94977.1 - 6.5e-12 45.2 0.0 2e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EMC94977.1 - 3.5e-05 22.7 0.0 0.0016 17.2 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 EMC94977.1 - 0.002 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs DUF3433 PF11915.3 EMC94978.1 - 1.3e-24 86.1 14.0 2.9e-14 52.9 2.6 4.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) adh_short PF00106.20 EMC94979.1 - 1.1e-24 87.2 0.5 1.5e-23 83.4 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC94979.1 - 1.6e-21 77.1 1.4 7.7e-21 74.9 1.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC94979.1 - 8.6e-10 38.5 0.1 1.7e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMC94979.1 - 1.9e-05 23.9 0.3 0.0001 21.5 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 EMC94979.1 - 3.5e-05 23.9 0.8 0.00015 21.8 0.6 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EMC94979.1 - 0.0011 17.9 0.1 0.0018 17.2 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 EMC94979.1 - 0.019 15.3 0.1 0.25 11.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EMC94979.1 - 0.041 13.8 0.2 0.12 12.3 0.1 1.8 2 1 0 2 2 2 0 NADH(P)-binding FAD_binding_3 PF01494.14 EMC94980.1 - 6.9e-25 87.8 0.1 2.6e-12 46.5 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EMC94980.1 - 6.5e-07 28.5 0.4 0.00038 19.5 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 EMC94980.1 - 3.6e-06 26.1 0.6 0.00012 21.1 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 EMC94980.1 - 0.00017 20.5 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EMC94980.1 - 0.00059 19.7 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMC94980.1 - 0.0012 17.5 0.0 0.004 15.8 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EMC94980.1 - 0.0014 18.6 0.1 0.0042 17.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMC94980.1 - 0.0085 14.6 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMC94980.1 - 0.009 16.0 0.0 0.024 14.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC94980.1 - 0.0091 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMC94980.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EMC94980.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC94980.1 - 0.063 12.3 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family DUF4336 PF14234.1 EMC94981.1 - 9e-16 57.8 0.0 2.6e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Thioesterase PF00975.15 EMC94983.1 - 1.3e-25 90.9 0.0 2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EMC94983.1 - 1.5e-06 28.3 0.0 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 EMC94983.1 - 2.3e-05 24.5 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EMC94983.1 - 0.00015 21.5 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox PF00070.22 EMC94983.1 - 0.019 15.3 0.1 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2974 PF11187.3 EMC94983.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SNase PF00565.12 EMC94984.1 - 4e-24 84.9 0.2 6.8e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Topoisom_I_N PF02919.10 EMC94985.1 - 1.2e-96 322.1 7.1 1.2e-96 322.1 4.9 3.6 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EMC94985.1 - 1.3e-82 276.4 2.1 1.3e-82 276.4 1.5 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EMC94985.1 - 2.3e-30 104.0 0.1 9.2e-30 102.1 0.1 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.14 EMC94986.1 - 1.3e-72 244.6 2.2 1.4e-72 244.4 1.5 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S3_C PF00189.15 EMC94986.1 - 0.022 14.9 0.4 0.046 13.9 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain Fungal_trans PF04082.13 EMC94987.1 - 4.4e-15 55.2 0.5 7.6e-15 54.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94987.1 - 9.7e-08 31.8 11.1 1.8e-07 30.9 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EMC94987.1 - 0.61 9.0 2.5 0.97 8.3 1.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PHD PF00628.24 EMC94988.1 - 2e-05 24.1 5.7 3.1e-05 23.5 4.0 1.3 1 0 0 1 1 1 1 PHD-finger Abhydrolase_6 PF12697.2 EMC94989.1 - 3.6e-23 82.6 0.0 4.6e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC94989.1 - 9.1e-16 58.1 0.0 3.6e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC94989.1 - 4.3e-13 49.2 0.0 1.5e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC94989.1 - 0.027 13.9 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMC94989.1 - 0.031 13.5 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2424 PF10340.4 EMC94989.1 - 0.057 12.0 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Hydrolase_4 PF12146.3 EMC94989.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase BAAT_C PF08840.6 EMC94989.1 - 0.08 12.6 0.0 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cu-oxidase_3 PF07732.10 EMC94990.1 - 2e-37 127.4 0.4 2e-37 127.4 0.3 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC94990.1 - 3.2e-31 107.6 3.2 3.2e-31 107.6 2.2 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EMC94990.1 - 5.4e-31 107.6 0.6 2.3e-29 102.3 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase ERO1 PF04137.10 EMC94993.1 - 2.6e-135 451.0 0.0 3.1e-135 450.8 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF423 PF04241.10 EMC94994.1 - 2.7e-25 88.1 0.6 3.6e-25 87.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF4341 PF14241.1 EMC94994.1 - 8.4 6.1 11.2 15 5.3 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4341) Vps8 PF12816.2 EMC94995.1 - 1.7e-65 219.9 0.0 3.1e-65 219.1 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EMC94995.1 - 2.1e-06 27.4 0.0 0.19 11.3 0.0 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EMC94995.1 - 2.5e-06 27.1 0.4 6.6e-06 25.8 0.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC94995.1 - 0.00049 20.0 0.3 0.0012 18.8 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC94995.1 - 0.0054 16.4 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC94995.1 - 0.0083 15.7 0.1 0.021 14.4 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC94995.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMC94995.1 - 0.019 14.6 0.3 0.019 14.6 0.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 EMC94995.1 - 0.1 12.4 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat PHD PF00628.24 EMC94995.1 - 0.35 10.6 2.6 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 PHD-finger DUF3752 PF12572.3 EMC94996.1 - 1.1e-31 109.9 13.0 1.1e-31 109.9 9.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) RCR PF12273.3 EMC94997.1 - 2.6e-11 44.2 0.8 3.1e-11 43.9 0.5 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red WWbp PF10349.4 EMC94997.1 - 0.11 13.3 9.2 0.14 13.0 6.4 1.1 1 0 0 1 1 1 0 WW-domain ligand protein DUF59 PF01883.14 EMC94998.1 - 1.8e-08 34.2 0.0 4.4e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF59 Fungal_trans PF04082.13 EMC94999.1 - 1.9e-09 36.8 0.6 1.9e-09 36.8 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC94999.1 - 8.1e-07 28.8 7.2 8.1e-07 28.8 5.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMC95000.1 - 1.5e-33 115.9 27.4 2.1e-33 115.5 19.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily 7tm_2 PF00002.19 EMC95002.1 - 2.1e-06 27.0 7.8 3.2e-05 23.1 5.4 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) DcuA_DcuB PF03605.9 EMC95002.1 - 0.00099 18.0 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter DUF1708 PF08101.6 EMC95004.1 - 6.9e-142 473.1 0.0 9.5e-142 472.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Thioredoxin PF00085.15 EMC95005.1 - 2.4e-33 113.9 0.0 9.4e-27 92.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EMC95005.1 - 3.7e-08 33.5 0.1 0.015 15.5 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC95005.1 - 1.2e-05 25.3 0.0 0.014 15.4 0.0 3.3 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EMC95005.1 - 0.0046 16.6 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family ERp29_N PF07912.8 EMC95005.1 - 0.019 14.8 0.0 0.056 13.3 0.0 1.7 2 0 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_7 PF13899.1 EMC95005.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like DUF605 PF04652.11 EMC95006.1 - 3.5e-86 289.9 27.2 1.2e-84 284.9 18.9 2.1 1 1 0 1 1 1 1 Vta1 like PhoPQ_related PF10142.4 EMC95007.1 - 0.048 12.1 0.1 0.072 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DUF3809 PF12723.2 EMC95007.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) Sec6 PF06046.8 EMC95008.1 - 2e-135 452.1 0.0 4.8e-135 450.8 0.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Cas_APE2256 PF09651.5 EMC95008.1 - 0.0042 16.8 0.2 0.54 9.9 0.0 3.4 3 0 0 3 3 3 1 CRISPR-associated protein (Cas_APE2256) zf-ZPR1 PF03367.8 EMC95008.1 - 0.032 13.4 0.2 0.098 11.8 0.0 1.9 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Vps53_N PF04100.7 EMC95008.1 - 0.2 10.3 0.8 0.59 8.8 0.1 2.2 3 0 0 3 3 3 0 Vps53-like, N-terminal Ribosomal_L30 PF00327.15 EMC95009.1 - 2.5e-09 36.5 0.0 3.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MarR_2 PF12802.2 EMC95009.1 - 0.038 13.6 0.1 0.056 13.1 0.1 1.3 1 0 0 1 1 1 0 MarR family Clat_adaptor_s PF01217.15 EMC95011.1 - 3.7e-43 146.6 0.1 3.7e-42 143.4 0.1 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain OSCP PF00213.13 EMC95016.1 - 5.7e-41 140.2 0.6 6.8e-41 139.9 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit vATP-synt_E PF01991.13 EMC95016.1 - 0.083 12.1 0.2 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Parathyroid PF01279.12 EMC95017.1 - 0.015 15.9 0.2 0.023 15.3 0.1 1.3 1 0 0 1 1 1 0 Parathyroid hormone family DUF2868 PF11067.3 EMC95017.1 - 0.097 11.7 0.2 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Pectate_lyase_3 PF12708.2 EMC95018.1 - 5.5e-73 245.8 12.2 1.2e-65 221.7 4.0 2.8 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EMC95018.1 - 0.00088 18.6 3.9 0.069 12.6 0.3 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EMC95018.1 - 0.0067 16.1 5.1 0.0067 16.1 3.6 3.7 3 1 0 3 3 3 2 Right handed beta helix region IMS PF00817.15 EMC95019.1 - 2.9e-35 121.2 0.0 5.4e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMC95019.1 - 1.4e-06 28.2 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMC95019.1 - 0.0061 16.5 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH_8 PF14716.1 EMC95019.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ribosomal_L16 PF00252.13 EMC95021.1 - 7.2e-28 96.9 0.0 9.6e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 EMC95022.1 - 2.8e-52 176.5 0.0 6.4e-52 175.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EMC95022.1 - 6.8e-14 51.7 0.0 2.8e-13 49.8 0.0 2.1 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EMC95022.1 - 1.3e-09 38.3 0.1 4.2e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC95022.1 - 1.6e-05 25.0 0.0 4.6e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EMC95022.1 - 6e-05 21.9 0.0 0.00012 20.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EMC95022.1 - 6.4e-05 23.7 0.0 0.00021 22.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC95022.1 - 0.00016 21.7 0.1 0.0079 16.1 0.1 3.1 1 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EMC95022.1 - 0.00085 19.0 0.1 0.0023 17.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EMC95022.1 - 0.0015 18.4 0.1 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC95022.1 - 0.0033 17.7 0.7 0.01 16.1 0.1 2.2 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EMC95022.1 - 0.0042 16.1 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMC95022.1 - 0.0055 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain PTCB-BRCT PF12738.2 EMC95022.1 - 0.011 15.5 0.0 0.038 13.8 0.0 2.0 1 0 0 1 1 1 0 twin BRCT domain AAA_28 PF13521.1 EMC95022.1 - 0.014 15.3 0.9 0.045 13.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EMC95022.1 - 0.038 13.4 0.1 9.4 5.6 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.7 EMC95022.1 - 0.043 13.4 0.0 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 EMC95022.1 - 0.078 12.6 0.1 0.46 10.1 0.0 2.3 3 0 0 3 3 3 0 NTPase RNA_helicase PF00910.17 EMC95022.1 - 0.17 12.0 0.3 0.55 10.4 0.0 2.1 2 0 0 2 2 1 0 RNA helicase SPT6_acidic PF14632.1 EMC95022.1 - 2.7 8.1 16.6 0.06 13.5 6.4 2.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Metallothio_Pro PF02069.11 EMC95023.1 - 0.032 14.0 0.3 0.055 13.2 0.2 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein Plasmodium_Vir PF05795.6 EMC95024.1 - 0.13 11.4 1.1 0.16 11.1 0.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PTH2 PF01981.11 EMC95026.1 - 3.3e-45 152.5 0.6 4.6e-45 152.0 0.4 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Sulfatase PF00884.18 EMC95028.1 - 1.4e-51 175.5 0.0 2e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EMC95028.1 - 1.9e-21 75.6 2.0 3.9e-21 74.6 1.4 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EMC95028.1 - 1.7e-11 44.1 0.1 8.4e-11 41.7 0.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EMC95028.1 - 0.00032 20.9 0.0 0.0015 18.8 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 EMC95028.1 - 0.009 14.4 0.0 0.014 13.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Tox-HDC PF15656.1 EMC95028.1 - 0.053 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Metalloenzyme PF01676.13 EMC95028.1 - 0.13 11.6 0.0 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Metalloenzyme superfamily PIR PF00399.14 EMC95029.1 - 1.3e-42 141.7 66.1 1.6e-07 30.4 2.7 7.4 7 0 0 7 7 7 6 Yeast PIR protein repeat B1 PF02246.10 EMC95029.1 - 0.11 12.3 0.1 0.38 10.6 0.0 1.9 1 0 0 1 1 1 0 Protein L b1 domain KAR9 PF08580.5 EMC95029.1 - 5.7 5.0 8.5 7.1 4.7 5.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Gon7 PF08738.5 EMC95030.1 - 2.4e-14 53.1 4.0 9.5e-14 51.2 2.8 1.8 1 1 0 1 1 1 1 Gon7 family DUF4611 PF15387.1 EMC95030.1 - 0.03 14.4 2.0 0.042 13.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) BSP_II PF05432.6 EMC95030.1 - 0.032 13.4 2.4 0.033 13.4 1.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ADH_zinc_N PF00107.21 EMC95031.1 - 1.8e-10 40.4 0.1 6.1e-10 38.7 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC95031.1 - 0.00017 21.2 0.0 0.00042 20.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMC95031.1 - 0.00021 22.2 0.0 0.00045 21.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3326 PF11805.3 EMC95031.1 - 0.026 13.2 0.0 0.041 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) NAD_binding_10 PF13460.1 EMC95031.1 - 0.039 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Rep_fac_C PF08542.6 EMC95032.1 - 7.9e-23 80.2 0.1 1.5e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EMC95032.1 - 6.4e-12 45.4 0.0 1.1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EMC95032.1 - 3.7e-06 27.1 0.1 8.7e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC95032.1 - 0.00022 21.3 1.0 0.0015 18.7 0.4 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC95032.1 - 0.00031 20.7 2.1 0.032 14.2 0.9 2.9 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EMC95032.1 - 0.004 17.4 0.0 0.0098 16.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EMC95032.1 - 0.0042 16.5 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 EMC95032.1 - 0.0069 16.4 0.2 0.28 11.2 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_10 PF12846.2 EMC95032.1 - 0.018 14.4 0.1 0.5 9.7 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain SNF2_N PF00176.18 EMC95032.1 - 0.032 13.0 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_23 PF13476.1 EMC95032.1 - 0.054 13.8 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EMC95032.1 - 0.06 12.5 0.0 0.19 10.9 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMC95032.1 - 0.12 12.0 0.3 0.36 10.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) HAD_2 PF13419.1 EMC95034.1 - 1.5e-19 70.8 0.0 2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMC95034.1 - 0.0017 18.2 0.0 0.076 12.9 0.0 2.7 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC95034.1 - 0.026 14.9 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase GAD-like PF08887.6 EMC95034.1 - 0.035 14.1 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 GAD-like domain Hydrolase_like PF13242.1 EMC95034.1 - 0.11 12.2 0.0 2.1 8.0 0.0 2.4 2 1 0 2 2 2 0 HAD-hyrolase-like C2 PF00168.25 EMC95035.1 - 1.3e-20 73.0 0.0 9e-15 54.2 0.0 2.7 2 0 0 2 2 2 2 C2 domain Amidohydro_4 PF13147.1 EMC95036.1 - 1.6e-09 38.1 2.1 1.1e-05 25.6 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 EMC95036.1 - 1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMC95036.1 - 1.6e-05 24.3 0.0 3.4e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family WD40 PF00400.27 EMC95037.1 - 1.7e-20 72.0 17.2 0.00015 21.5 0.0 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat ALIX_LYPXL_bnd PF13949.1 EMC95037.1 - 0.068 12.1 0.7 0.1 11.5 0.5 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AMP-binding PF00501.23 EMC95038.1 - 1.3e-92 310.3 0.2 1.6e-92 310.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC95038.1 - 1.4e-20 73.9 0.2 1.9e-18 67.1 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain EnY2 PF10163.4 EMC95039.1 - 5e-08 32.7 0.1 9.4e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 AfaD PF05775.7 EMC95039.1 - 0.052 13.5 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein MFS_1 PF07690.11 EMC95040.1 - 1.2e-21 76.8 59.6 1e-19 70.5 28.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EMC95040.1 - 0.002 16.7 19.4 0.002 16.7 13.5 2.2 1 1 2 3 3 3 1 Vacuole effluxer Atg22 like UvdE PF03851.9 EMC95041.1 - 1.7e-112 374.9 0.0 2.4e-112 374.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DOCK-C2 PF14429.1 EMC95042.1 - 1.9e-23 83.0 0.0 3.7e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EMC95042.1 - 5.2e-14 51.9 0.1 1.2e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_9 PF14604.1 EMC95042.1 - 1.4e-07 31.0 1.1 4.6e-06 26.1 0.0 3.1 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.23 EMC95042.1 - 7.3e-07 28.4 0.0 2.1e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC95042.1 - 4.5e-05 22.8 0.0 0.0001 21.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Glyco_hydro_2 PF00703.16 EMC95043.1 - 2.6e-08 34.2 0.1 2.9e-06 27.7 0.0 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EMC95043.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain N6-adenineMlase PF10237.4 EMC95043.1 - 0.099 12.2 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Probable N6-adenine methyltransferase AA_permease_2 PF13520.1 EMC95044.1 - 1.7e-61 208.0 41.6 2.2e-61 207.6 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC95044.1 - 9.6e-20 70.3 35.7 1.2e-19 70.0 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease Metallophos_2 PF12850.2 EMC95045.1 - 6.2e-10 39.1 0.0 1.4e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EMC95045.1 - 4e-06 26.3 2.1 0.034 13.5 0.1 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase AKAP7_NLS PF10469.4 EMC95047.1 - 9.2e-21 74.5 0.0 3e-20 72.8 0.0 1.7 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain GET2 PF08690.5 EMC95048.1 - 7.7e-09 35.2 0.0 1.5e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 DUF4233 PF14017.1 EMC95048.1 - 0.22 11.4 5.2 0.16 11.8 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Ribosomal_L28 PF00830.14 EMC95049.1 - 2.4e-19 68.8 0.8 3.4e-19 68.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L28 family L51_S25_CI-B8 PF05047.11 EMC95050.1 - 2.2e-13 49.6 0.0 3.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF566 PF04484.7 EMC95050.1 - 0.014 14.8 3.7 0.021 14.3 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ubiquitin_3 PF14836.1 EMC95051.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_16 PF13191.1 EMC95052.1 - 5.7e-09 36.2 0.2 1.5e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 EMC95052.1 - 5e-08 32.7 0.0 9.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMC95052.1 - 3.9e-06 27.0 0.0 1.9e-05 24.7 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EMC95052.1 - 0.0046 16.8 0.0 0.025 14.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EMC95052.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EMC95052.1 - 0.021 13.8 0.0 0.09 11.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EMC95052.1 - 0.023 14.8 0.5 0.24 11.5 0.0 2.7 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EMC95052.1 - 0.054 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Fringe PF02434.11 EMC95053.1 - 1.5e-05 24.3 0.1 0.0004 19.6 0.0 2.4 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 EMC95053.1 - 0.015 15.0 0.6 0.041 13.5 0.4 1.7 1 0 0 1 1 1 0 PAN domain CENP-Q PF13094.1 EMC95054.1 - 0.0013 18.7 0.4 0.0016 18.5 0.3 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Mod_r PF07200.8 EMC95054.1 - 0.011 15.7 0.7 0.016 15.1 0.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Mcm10 PF09332.6 EMC95054.1 - 0.033 13.5 3.3 0.036 13.4 2.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Spc7 PF08317.6 EMC95054.1 - 0.095 11.3 0.6 0.12 10.9 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EMC95054.1 - 0.098 12.4 2.7 0.15 11.8 1.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2360 PF10152.4 EMC95054.1 - 0.28 11.4 3.2 0.35 11.1 2.2 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SlyX PF04102.7 EMC95054.1 - 0.3 11.4 6.0 0.16 12.3 2.2 1.9 1 1 1 2 2 2 0 SlyX M PF02370.11 EMC95054.1 - 1.9 9.1 7.7 14 6.4 0.9 2.6 1 1 1 2 2 2 0 M protein repeat DUF2756 PF10956.3 EMC95054.1 - 2 8.6 5.6 1.1 9.5 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2756) RIC3 PF15361.1 EMC95054.1 - 2.1 8.5 13.3 0.099 12.8 3.2 2.0 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3695 PF12494.3 EMC95055.1 - 0.021 14.5 0.2 0.15 11.8 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3695) APH_6_hur PF04655.9 EMC95055.1 - 0.04 13.0 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Bromodomain PF00439.20 EMC95056.1 - 1.2e-19 69.9 0.0 2.4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain NuA4 PF09340.5 EMC95057.1 - 3.7e-25 87.3 0.0 6.5e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Lactamase_B PF00753.22 EMC95058.1 - 2e-05 24.3 0.7 3.2e-05 23.6 0.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily FAD_binding_2 PF00890.19 EMC95060.1 - 1.9e-81 274.0 0.1 2.7e-81 273.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EMC95060.1 - 1.8e-19 69.2 0.7 6.6e-17 61.0 0.0 3.4 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EMC95060.1 - 3.6e-12 45.8 1.5 3.2e-11 42.7 0.7 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMC95060.1 - 7.5e-10 38.4 0.4 2.8e-09 36.5 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC95060.1 - 3.6e-08 33.3 0.5 3.2e-07 30.2 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC95060.1 - 5.1e-07 29.7 0.0 6.4e-05 22.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC95060.1 - 1.9e-05 23.8 0.1 0.0045 16.1 0.0 2.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EMC95060.1 - 2.9e-05 22.7 7.6 4.2e-05 22.1 1.2 2.8 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EMC95060.1 - 5.7e-05 22.1 1.0 0.013 14.3 0.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 EMC95060.1 - 0.00067 18.8 0.2 1.2 8.1 0.0 3.5 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMC95060.1 - 0.00067 19.7 0.7 0.0027 17.7 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC95060.1 - 0.001 18.8 0.1 0.007 16.1 0.1 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EMC95060.1 - 0.004 16.2 0.2 0.0072 15.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EMC95060.1 - 0.0071 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EMC95060.1 - 0.089 11.6 0.1 0.98 8.2 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMC95060.1 - 0.097 13.0 3.5 1.7 9.1 0.6 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMC95060.1 - 0.1 12.1 0.1 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_3 PF00202.16 EMC95063.1 - 1.5e-98 329.8 0.0 1.8e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMC95063.1 - 0.00024 20.1 0.0 0.00038 19.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_3 PF00933.16 EMC95065.1 - 4.5e-49 167.0 0.0 6.4e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMC95065.1 - 1.7e-41 142.2 0.4 2.6e-41 141.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Ribosomal_S8e PF01201.17 EMC95067.1 - 2.2e-47 160.4 3.1 2.9e-47 160.1 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e DDE_Tnp_4 PF13359.1 EMC95067.1 - 0.028 14.0 1.1 0.47 10.0 0.1 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease S10_plectin PF03501.10 EMC95068.1 - 4.8e-41 138.5 0.3 5.8e-41 138.2 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Caprin-1_C PF12287.3 EMC95068.1 - 3.8 6.8 5.8 4.5 6.5 4.0 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Peptidase_M20 PF01546.23 EMC95069.1 - 3.3e-23 82.1 0.2 7.2e-23 81.0 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMC95069.1 - 3.8e-06 26.6 0.1 1.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMC95069.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Sugar_tr PF00083.19 EMC95070.1 - 4.9e-75 252.8 30.6 5.6e-75 252.6 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC95070.1 - 4.3e-21 75.0 28.4 4.3e-21 75.0 19.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily SPX PF03105.14 EMC95071.1 - 2.8e-49 168.3 0.5 3.8e-49 167.9 0.4 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EMC95071.1 - 2.1e-27 96.1 41.6 3e-27 95.6 28.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMC95071.1 - 4.4e-15 55.1 45.5 2.7e-13 49.2 12.3 2.2 1 1 1 2 2 2 2 Citrate transporter DUF3043 PF11241.3 EMC95071.1 - 0.15 11.6 2.7 0.41 10.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) Ldh_2 PF02615.9 EMC95072.1 - 1.6e-100 336.0 0.0 1.9e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase zf-CSL PF05207.8 EMC95073.1 - 1.2e-22 79.1 2.0 1.5e-22 78.8 1.4 1.1 1 0 0 1 1 1 1 CSL zinc finger Terminase_GpA PF05876.7 EMC95073.1 - 0.0063 14.9 0.1 0.0075 14.6 0.1 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.7 EMC95073.1 - 0.025 13.9 1.0 0.057 12.7 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.7 EMC95073.1 - 0.11 12.2 0.4 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Frataxin_Cyay PF01491.11 EMC95074.1 - 5.7e-33 112.9 0.0 7.2e-33 112.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain BiPBP_C PF06832.7 EMC95074.1 - 0.007 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family OPA3 PF07047.7 EMC95075.1 - 1.1e-32 112.6 7.7 4.7e-32 110.5 5.3 2.3 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) GAGA_bind PF06217.7 EMC95075.1 - 3.8 7.4 11.0 0.29 11.0 3.5 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family Mnd1 PF03962.10 EMC95075.1 - 3.8 7.1 10.6 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Mnd1 family GrpE PF01025.14 EMC95075.1 - 4 6.9 17.0 3 7.3 0.2 3.1 3 0 0 3 3 3 0 GrpE RRM_1 PF00076.17 EMC95077.1 - 7.2e-12 44.7 1.2 2.8e-11 42.9 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95077.1 - 2.7e-11 43.2 0.4 1.5e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95077.1 - 8.6e-07 28.7 0.1 2.1e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC95077.1 - 0.21 11.4 1.7 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif Glyco_hydro_16 PF00722.16 EMC95079.1 - 2.2e-07 30.3 0.5 5.7e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 GFA PF04828.9 EMC95080.1 - 2.9e-15 55.9 0.0 4.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Helicase_C PF00271.26 EMC95081.1 - 7.4e-20 70.5 0.1 2e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC95081.1 - 4.7e-19 68.4 0.0 9.7e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EMC95081.1 - 2.6e-17 63.2 0.0 8.3e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMC95081.1 - 0.0005 18.9 0.1 0.00077 18.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EMC95081.1 - 0.1 12.7 0.0 0.43 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EMC95081.1 - 0.12 11.3 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KH_1 PF00013.24 EMC95082.1 - 4e-41 138.4 14.3 3.4e-14 52.2 1.4 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMC95082.1 - 4.1e-32 109.2 11.1 1.2e-10 40.8 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMC95082.1 - 4e-14 51.9 5.7 0.00031 20.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMC95082.1 - 3.2e-09 36.3 3.8 0.038 13.6 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMC95082.1 - 1e-06 28.4 3.4 0.038 13.8 0.1 3.5 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 EMC95082.1 - 0.043 13.2 0.0 7.4 6.0 0.0 3.0 3 0 0 3 3 3 0 dUTPase GRP PF07172.6 EMC95082.1 - 0.065 13.7 12.6 1.5 9.3 2.2 2.6 2 0 0 2 2 2 0 Glycine rich protein family GCN5L1 PF06320.8 EMC95083.1 - 2.1e-08 34.0 0.8 2.5e-08 33.7 0.6 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) GTA_TIM PF13547.1 EMC95083.1 - 0.043 12.8 0.4 0.05 12.5 0.3 1.1 1 0 0 1 1 1 0 GTA TIM-barrel-like domain AAA_13 PF13166.1 EMC95083.1 - 0.081 11.3 1.0 0.09 11.2 0.7 1.0 1 0 0 1 1 1 0 AAA domain HAUS6_N PF14661.1 EMC95083.1 - 0.25 10.6 3.8 0.27 10.5 2.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Rabaptin PF03528.10 EMC95083.1 - 1.3 8.9 5.2 4.8 7.1 3.6 1.9 1 1 0 1 1 1 0 Rabaptin DUF3708 PF12501.3 EMC95083.1 - 1.9 8.2 5.2 2.2 8.0 3.5 1.2 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Ald_Xan_dh_C2 PF02738.13 EMC95084.1 - 1e-196 654.5 0.3 1.3e-196 654.1 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EMC95084.1 - 1.4e-48 164.5 0.0 2.7e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EMC95084.1 - 8e-32 109.2 0.0 2.5e-31 107.6 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EMC95084.1 - 1.3e-31 108.9 0.0 2.9e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EMC95084.1 - 3.1e-29 100.6 0.0 6.8e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EMC95084.1 - 9e-08 31.7 0.2 9e-08 31.7 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.11 EMC95084.1 - 0.1 12.4 0.1 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 region 3 SKN1 PF03935.10 EMC95086.1 - 5.3e-213 707.7 0.2 6.2e-213 707.4 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Diphthamide_syn PF01866.12 EMC95087.1 - 2.5e-108 361.9 0.0 3.1e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Arginase PF00491.16 EMC95089.1 - 4e-89 298.6 0.0 5e-89 298.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMC95089.1 - 0.065 13.4 0.1 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 UPF0489 domain MatE PF01554.13 EMC95090.1 - 5.7e-53 178.8 24.0 6.3e-28 97.4 6.7 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EMC95090.1 - 4.4e-08 33.0 6.5 4.4e-08 33.0 4.5 4.0 3 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 EMC95090.1 - 0.0053 16.2 2.3 0.024 14.1 0.7 2.6 2 0 0 2 2 2 1 Interferon-induced transmembrane protein AA_permease_2 PF13520.1 EMC95091.1 - 7.9e-40 136.6 52.0 1e-39 136.2 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC95091.1 - 2.9e-21 75.3 42.9 3.9e-21 74.9 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease GPI2 PF06432.6 EMC95091.1 - 0.083 12.2 0.1 0.083 12.2 0.1 2.7 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase MFS_1 PF07690.11 EMC95092.1 - 2.2e-17 62.8 33.7 9.3e-09 34.4 4.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EMC95092.1 - 0.00048 18.7 10.1 0.00048 18.7 7.0 2.3 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like SART-1 PF03343.8 EMC95093.1 - 4.1e-134 448.2 60.7 5e-134 447.9 42.1 1.1 1 0 0 1 1 1 1 SART-1 family MRG PF05712.8 EMC95094.1 - 2.2e-49 167.0 0.1 3.3e-49 166.4 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EMC95094.1 - 1.5e-08 34.1 1.8 3.3e-08 33.1 1.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EMC95094.1 - 0.013 15.1 1.2 0.029 14.0 0.9 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain His_Phos_1 PF00300.17 EMC95096.1 - 2.1e-26 92.9 0.0 2.9e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EMC95096.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) 2-Hacid_dh_C PF02826.14 EMC95097.1 - 4.7e-40 136.6 0.0 6.2e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC95097.1 - 5.9e-19 67.8 0.0 7e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NTP_transf_3 PF12804.2 EMC95097.1 - 0.0049 16.9 0.0 0.074 13.1 0.0 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain NAD_binding_2 PF03446.10 EMC95097.1 - 0.0054 16.5 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EMC95098.1 - 7.4e-31 107.3 4.0 8.1e-31 107.1 1.7 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC95098.1 - 3e-16 59.9 0.8 3.7e-16 59.6 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC95098.1 - 1.7e-12 47.3 2.4 2.3e-12 46.9 1.1 1.6 2 0 0 2 2 2 1 KR domain HEM4 PF02602.10 EMC95098.1 - 0.031 13.4 0.2 0.047 12.9 0.1 1.5 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD B12D PF06522.6 EMC95099.1 - 5.9e-06 25.8 0.0 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Pyridoxal_deC PF00282.14 EMC95100.1 - 7.8e-22 77.2 0.0 1.1e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMC95100.1 - 0.00021 20.1 0.0 0.00041 19.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMC95100.1 - 0.0044 16.1 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1775 PF07987.6 EMC95100.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) Mto2_bdg PF12808.2 EMC95100.1 - 0.095 12.8 0.1 0.095 12.8 0.1 1.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WD40 PF00400.27 EMC95102.1 - 2.1e-17 62.2 5.1 0.006 16.4 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 EMC95102.1 - 1.4e-07 31.3 0.1 1.4e-07 31.3 0.1 2.3 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 EMC95102.1 - 0.18 11.5 1.3 0.63 9.8 0.0 2.4 2 1 0 2 2 2 0 Prp18 domain RRM_1 PF00076.17 EMC95103.1 - 8.3e-17 60.5 0.0 1.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95103.1 - 2.6e-11 43.3 0.0 3.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95103.1 - 4.3e-09 36.0 0.0 6.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC95103.1 - 0.045 13.5 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 RRM_3 PF08777.6 EMC95103.1 - 0.12 12.2 0.0 0.78 9.6 0.0 2.0 1 1 0 1 1 1 0 RNA binding motif Fungal_trans_2 PF11951.3 EMC95104.1 - 5.6e-51 173.3 1.5 1e-50 172.4 1.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC95104.1 - 2.1e-06 27.5 7.4 4e-06 26.6 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMC95106.1 - 7.3e-07 29.2 0.1 1.2e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC95106.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 EMC95106.1 - 0.019 14.4 0.1 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family GMC_oxred_N PF00732.14 EMC95107.1 - 1.8e-58 198.0 0.0 3.9e-58 196.9 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC95107.1 - 8.8e-35 120.1 0.0 1.6e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMC95107.1 - 8.3e-07 28.2 0.0 0.0026 16.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMC95107.1 - 0.00016 20.7 0.0 0.00029 19.8 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMC95107.1 - 0.00077 19.4 0.0 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC95107.1 - 0.0015 17.4 0.0 0.0095 14.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC95107.1 - 0.018 14.9 0.0 0.063 13.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC95107.1 - 0.044 13.5 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMC95107.1 - 0.077 13.0 0.0 6.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_1 PF00515.23 EMC95108.1 - 2.7e-56 185.0 25.0 7.5e-09 34.8 0.0 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMC95108.1 - 7.5e-51 166.0 17.1 1.3e-06 27.8 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EMC95108.1 - 1.1e-50 169.0 28.1 1.4e-13 50.2 1.4 6.4 3 2 4 7 7 7 7 TPR repeat TPR_8 PF13181.1 EMC95108.1 - 6.1e-41 135.1 15.5 5.5e-06 25.7 0.0 10.3 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 EMC95108.1 - 4.4e-32 107.5 11.9 3e-05 23.8 0.0 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMC95108.1 - 1.6e-31 108.2 8.9 4.9e-07 30.2 0.0 6.6 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMC95108.1 - 1.7e-31 107.9 19.9 9.3e-07 28.7 0.0 7.4 3 2 3 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 EMC95108.1 - 7.4e-28 94.5 10.4 0.00017 21.9 0.0 10.1 4 3 6 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 EMC95108.1 - 1.1e-25 87.2 10.3 0.00082 18.9 0.0 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.1 EMC95108.1 - 1.4e-24 84.7 17.4 0.00042 20.5 0.0 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC95108.1 - 1.4e-23 82.9 15.1 2.4e-06 27.7 0.0 6.7 5 2 0 6 6 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EMC95108.1 - 1.6e-14 53.7 12.6 1e-08 35.2 1.4 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EMC95108.1 - 1.2e-13 50.7 12.2 0.00037 20.2 0.1 6.9 2 1 5 8 8 8 5 Tetratricopeptide repeat TPR_15 PF13429.1 EMC95108.1 - 1e-08 34.6 12.8 0.00019 20.6 1.3 5.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 EMC95108.1 - 2.8e-05 24.0 11.4 0.086 12.7 2.2 4.2 3 2 1 4 4 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 EMC95108.1 - 0.00025 21.0 2.8 0.18 11.9 0.0 4.9 4 1 1 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC95108.1 - 0.00029 20.6 0.1 11 5.9 0.0 4.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 EMC95108.1 - 0.0028 17.1 1.7 0.93 8.9 0.0 3.3 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 EMC95108.1 - 0.0094 14.7 1.8 4.1 6.0 0.0 3.0 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Clathrin PF00637.15 EMC95108.1 - 0.043 13.4 0.9 11 5.5 0.0 3.6 2 1 1 3 3 3 0 Region in Clathrin and VPS GAS PF13851.1 EMC95108.1 - 0.052 12.7 0.2 0.12 11.5 0.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SNAP PF14938.1 EMC95108.1 - 0.18 10.8 17.2 11 5.0 0.7 5.0 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP BTAD PF03704.12 EMC95108.1 - 0.29 11.4 12.2 5.3 7.3 0.0 4.6 3 1 2 5 5 5 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 EMC95108.1 - 1.1 9.2 13.6 17 5.5 0.1 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 EMC95109.1 - 5.4e-17 62.5 0.0 3.1e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC95109.1 - 7.4e-13 47.5 0.0 9.1e-05 20.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EMC95109.1 - 5.6e-09 35.9 0.0 5.1e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC95109.1 - 3.6e-08 33.5 0.0 1.6e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC95109.1 - 6.3e-08 32.5 0.0 1.8e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMC95109.1 - 0.00051 18.6 0.2 0.0015 17.1 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 EMC95109.1 - 0.00076 18.5 0.1 0.0044 15.9 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EMC95109.1 - 0.0014 17.7 0.0 0.0088 15.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EMC95109.1 - 0.0016 18.8 0.0 0.059 13.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC95109.1 - 0.013 14.3 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EMC95109.1 - 0.027 13.5 0.1 0.057 12.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 EMC95109.1 - 0.034 14.3 0.0 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 EMC95109.1 - 0.04 13.0 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF3936 PF13072.1 EMC95109.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) UDPG_MGDP_dh_N PF03721.9 EMC95109.1 - 0.24 10.7 0.1 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_syntA PF00290.15 EMC95110.1 - 5.2e-88 293.9 0.0 7.9e-88 293.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EMC95110.1 - 3.1e-43 148.1 1.7 5.2e-43 147.4 1.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme OGG_N PF07934.7 EMC95113.1 - 1.7e-32 111.8 0.0 3e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EMC95113.1 - 2e-14 53.7 0.0 3.2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMC95113.1 - 0.0046 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif MutS_V PF00488.16 EMC95114.1 - 9.6e-82 273.9 0.0 1.5e-81 273.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC95114.1 - 1.3e-39 136.1 6.9 1.5e-39 135.8 4.0 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EMC95114.1 - 5.6e-19 68.2 0.0 1.3e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMC95114.1 - 3.7e-08 33.5 0.0 9.6e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.1 EMC95114.1 - 0.0011 18.8 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MutS_IV PF05190.13 EMC95114.1 - 0.0056 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EMC95114.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EMC95114.1 - 0.18 12.0 0.2 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain URO-D PF01208.12 EMC95115.1 - 4.9e-124 413.7 0.0 5.6e-124 413.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) BING4CT PF08149.6 EMC95115.1 - 0.017 14.6 0.1 0.098 12.1 0.0 2.0 2 0 0 2 2 2 0 BING4CT (NUC141) domain dCMP_cyt_deam_1 PF00383.17 EMC95116.1 - 1.5e-23 82.4 0.1 2.2e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMC95116.1 - 0.0015 18.3 2.6 0.088 12.6 0.8 2.3 1 1 1 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 EMC95116.1 - 0.0021 17.7 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 EMC95116.1 - 0.04 13.5 0.1 0.084 12.4 0.1 1.7 1 1 0 1 1 1 0 APOBEC-like N-terminal domain MafB19-deam PF14437.1 EMC95116.1 - 0.04 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase PAH PF02671.16 EMC95117.1 - 7.3e-45 150.3 0.3 1.2e-16 60.0 0.3 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EMC95117.1 - 2.8e-38 129.7 0.1 6.9e-38 128.4 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Alpha-L-AF_C PF06964.7 EMC95118.1 - 9e-34 116.7 0.3 9e-34 116.7 0.2 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EMC95118.1 - 0.00027 20.9 2.3 0.00027 20.9 1.6 2.1 2 1 0 2 2 2 1 Carbohydrate binding domain Peptidase_M75 PF09375.5 EMC95118.1 - 0.039 13.2 0.1 0.066 12.5 0.1 1.2 1 0 0 1 1 1 0 Imelysin Aldolase_II PF00596.16 EMC95119.1 - 2.7e-43 147.7 0.0 9.8e-43 145.8 0.0 1.7 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NAD_binding_10 PF13460.1 EMC95120.1 - 8.6e-11 42.1 0.0 1.5e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC95120.1 - 1.4e-06 27.7 0.0 2.7e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Pkinase PF00069.20 EMC95121.1 - 4.1e-60 203.1 0.0 5.7e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC95121.1 - 3e-43 147.7 0.0 4.5e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EMC95121.1 - 4.4e-09 36.1 0.1 0.00057 19.8 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EMC95121.1 - 6e-09 35.2 0.0 1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UDG PF03167.14 EMC95121.1 - 0.061 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Kdo PF06293.9 EMC95121.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin_4 PF13462.1 EMC95122.1 - 1.8e-11 44.3 0.0 4.4e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EMC95122.1 - 0.022 14.3 1.2 0.19 11.2 0.3 2.4 1 1 1 2 2 2 0 DSBA-like thioredoxin domain HATPase_c PF02518.21 EMC95123.1 - 6.7e-11 41.8 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMC95123.1 - 2.4e-10 40.1 0.0 4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EMC95123.1 - 5e-10 38.8 0.0 1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF596 PF04591.7 EMC95123.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF596 Transferase PF02458.10 EMC95124.1 - 2.5e-16 59.1 0.0 3.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Transferase family RE_Eco29kI PF09517.5 EMC95124.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Eco29kI restriction endonuclease DUF1776 PF08643.5 EMC95125.1 - 7.1e-62 209.2 0.1 2.6e-53 181.0 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.20 EMC95125.1 - 0.0093 15.8 0.2 0.028 14.3 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC95125.1 - 0.049 13.3 0.0 0.089 12.5 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RRM_1 PF00076.17 EMC95127.1 - 1.6e-27 94.9 0.1 2.3e-11 43.1 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95127.1 - 3e-19 68.7 0.0 2.2e-05 24.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95127.1 - 3.1e-13 49.3 0.1 1.1e-07 31.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_29 PF13551.1 EMC95129.1 - 7.5e-07 29.2 0.2 7.5e-07 29.2 0.2 2.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_36 PF13730.1 EMC95129.1 - 0.0096 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EMC95129.1 - 0.019 14.6 1.7 0.033 13.8 0.2 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.1 EMC95129.1 - 0.034 14.9 0.1 0.034 14.9 0.1 4.4 4 2 1 5 5 5 0 Homeodomain-like domain Calreticulin PF00262.13 EMC95130.1 - 1.4e-164 547.0 13.0 1.9e-164 546.6 9.0 1.2 1 0 0 1 1 1 1 Calreticulin family Cytadhesin_P30 PF07271.6 EMC95130.1 - 0.027 13.7 0.1 0.056 12.7 0.1 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 Tape_meas_lam_C PF09718.5 EMC95130.1 - 0.027 14.3 3.9 0.77 9.7 0.3 2.3 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3365 PF11845.3 EMC95130.1 - 0.14 12.0 1.4 3.4 7.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) OAD_gamma PF04277.8 EMC95130.1 - 0.75 10.2 6.7 0.67 10.3 1.2 3.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF883 PF05957.8 EMC95130.1 - 1.2 9.5 13.8 0.41 11.0 4.2 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) FAD_binding_3 PF01494.14 EMC95131.1 - 4.5e-19 68.7 0.6 7e-19 68.0 0.4 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC95131.1 - 6.7e-05 21.9 0.0 0.28 10.0 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC95131.1 - 0.0004 20.4 0.0 0.00081 19.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC95131.1 - 0.00076 19.4 0.2 0.0039 17.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMC95131.1 - 0.0011 17.8 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EMC95131.1 - 0.014 14.3 0.5 4.9 5.9 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein HVSL PF09749.4 EMC95132.1 - 2.5e-39 134.7 0.0 3e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 EMC95132.1 - 0.00025 20.7 0.1 0.00035 20.3 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Pal1 PF08316.6 EMC95133.1 - 2.3e-08 34.6 1.7 7.9e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Pal1 cell morphology protein Aldedh PF00171.17 EMC95134.1 - 4.1e-135 450.6 1.2 5.3e-135 450.3 0.8 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC95134.1 - 0.0027 16.4 0.3 0.0091 14.7 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA reductase (LuxC) FAD_binding_3 PF01494.14 EMC95135.1 - 2.3e-13 49.9 0.0 3.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EMC95135.1 - 0.002 16.8 0.0 0.0034 16.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.19 EMC95135.1 - 0.0073 15.2 0.2 0.013 14.4 0.0 1.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase ABM PF03992.11 EMC95136.1 - 0.037 14.0 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase FAA_hydrolase PF01557.13 EMC95137.1 - 3.2e-50 170.5 0.0 4.3e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMC95137.1 - 5.7e-24 84.1 0.0 1.1e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Abhydrolase_6 PF12697.2 EMC95138.1 - 1.1e-24 87.6 0.1 1.3e-24 87.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC95138.1 - 8.9e-07 28.7 0.0 1.8e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC95138.1 - 0.00071 19.1 0.0 0.0023 17.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 EMC95138.1 - 0.18 10.0 0.0 0.25 9.5 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Form-deh_trans PF09163.6 EMC95139.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Fungal_trans PF04082.13 EMC95140.1 - 3.1e-24 85.2 1.0 6.6e-24 84.1 0.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PQ-loop PF04193.9 EMC95140.1 - 0.019 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 PQ loop repeat AMP-binding PF00501.23 EMC95141.1 - 3.1e-84 282.7 0.0 3.7e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC95141.1 - 2.3e-09 38.0 0.8 7.8e-09 36.3 0.2 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EMC95142.1 - 2.1e-05 24.1 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC95142.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 EMC95142.1 - 0.026 13.4 0.0 4.9 5.9 0.0 2.2 1 1 1 2 2 2 0 Male sterility protein Dabb PF07876.7 EMC95143.1 - 7.6e-13 48.7 0.3 9e-13 48.4 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aldedh PF00171.17 EMC95144.1 - 5.4e-139 463.4 0.0 6.1e-139 463.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMC95144.1 - 0.025 13.7 0.0 3.4 6.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1487) MFS_1 PF07690.11 EMC95145.1 - 9.6e-29 100.1 38.9 9.6e-29 100.1 26.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 EMC95145.1 - 5.8e-05 21.7 11.7 5.8e-05 21.7 8.1 2.6 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like HgmA PF04209.8 EMC95146.1 - 2.1e-179 596.3 0.0 2.4e-179 596.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Acyl-CoA_dh_1 PF00441.19 EMC95147.1 - 7e-37 126.8 0.5 9.8e-37 126.3 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC95147.1 - 5e-18 64.3 0.0 1.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC95147.1 - 2.5e-08 34.2 0.0 4.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC95147.1 - 2.8e-08 34.3 0.1 7.5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF1751 PF08551.5 EMC95151.1 - 1.7e-24 86.0 0.2 3.6e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EMC95151.1 - 7.1e-05 22.8 5.2 0.00015 21.7 3.6 1.5 1 0 0 1 1 1 1 Rhomboid family SP2 PF03014.9 EMC95151.1 - 0.065 11.1 2.5 0.096 10.5 1.7 1.1 1 0 0 1 1 1 0 Structural protein 2 LisH PF08513.6 EMC95152.1 - 3.7e-07 29.6 0.4 8.5e-07 28.5 0.3 1.7 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EMC95152.1 - 0.026 14.4 0.6 19 5.3 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Pyr_redox_3 PF13738.1 EMC95153.1 - 6.7e-23 81.8 0.0 1.4e-22 80.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC95153.1 - 2.8e-13 48.9 0.0 6.2e-12 44.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMC95153.1 - 1.3e-09 37.9 0.0 3e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMC95153.1 - 1.5e-06 27.3 0.0 0.00018 20.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMC95153.1 - 0.00034 19.6 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC95153.1 - 0.00036 20.3 0.3 0.014 15.1 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC95153.1 - 0.0015 18.4 0.0 0.11 12.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC95153.1 - 0.043 12.6 0.0 2.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EMC95153.1 - 0.054 11.9 0.0 0.089 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DEDD_Tnp_IS110 PF01548.12 EMC95153.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DUF4187 PF13821.1 EMC95155.1 - 2.6e-17 62.1 2.0 8.1e-17 60.5 1.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EMC95155.1 - 2.9e-09 36.5 3.0 5.3e-09 35.7 2.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC95155.1 - 0.005 16.6 1.7 0.017 14.9 1.1 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site FMN_red PF03358.10 EMC95156.1 - 2.1e-08 33.7 0.0 2.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EMC95156.1 - 2.5e-08 34.0 0.0 3.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EMC95156.1 - 4.4e-05 23.0 0.0 5.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EMC95156.1 - 0.003 16.9 0.1 0.025 13.9 0.1 2.0 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 EMC95156.1 - 0.042 13.8 0.0 0.44 10.5 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain F_actin_cap_B PF01115.12 EMC95157.1 - 1e-96 322.8 0.0 1.1e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit AAA PF00004.24 EMC95158.1 - 1.1e-14 54.8 0.0 2.7e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMC95158.1 - 7e-13 48.5 0.0 1.2e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EMC95158.1 - 2.8e-10 39.5 0.0 4.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EMC95158.1 - 3.2e-10 39.8 0.0 7.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EMC95158.1 - 9.1e-07 29.0 0.0 1.3e-05 25.3 0.0 2.8 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EMC95158.1 - 6.4e-06 25.3 0.0 1.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMC95158.1 - 1e-05 25.6 0.0 0.00023 21.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EMC95158.1 - 2.2e-05 24.0 0.0 9e-05 22.1 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_11 PF13086.1 EMC95158.1 - 2.6e-05 23.9 0.0 4.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC95158.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMC95158.1 - 0.00081 19.0 0.2 0.0045 16.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EMC95158.1 - 0.001 18.6 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EMC95158.1 - 0.0015 17.7 0.0 0.061 12.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMC95158.1 - 0.0022 18.8 0.0 0.0055 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMC95158.1 - 0.0024 16.8 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 EMC95158.1 - 0.0027 16.7 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EMC95158.1 - 0.0036 17.0 0.1 0.031 14.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMC95158.1 - 0.0039 16.6 0.7 0.014 14.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMC95158.1 - 0.0091 15.5 0.0 0.085 12.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMC95158.1 - 0.02 14.7 0.1 0.13 12.1 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMC95158.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMC95158.1 - 0.032 13.6 0.0 0.23 10.8 0.0 2.3 2 1 1 3 3 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EMC95158.1 - 0.032 13.7 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family TIP49 PF06068.8 EMC95158.1 - 0.038 12.7 0.0 0.1 11.2 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 EMC95158.1 - 0.044 14.0 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EMC95158.1 - 0.06 12.1 0.0 2.6 6.7 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain DEAD PF00270.24 EMC95158.1 - 0.085 12.3 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 EMC95158.1 - 0.088 12.9 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EMC95158.1 - 0.097 12.2 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_60s PF00428.14 EMC95158.1 - 0.13 12.6 7.3 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1746 PF08508.5 EMC95159.1 - 3e-39 133.5 0.1 4.3e-39 133.0 0.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Zip PF02535.17 EMC95160.1 - 8.2e-46 156.4 0.1 1.1e-45 156.0 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter CBS PF00571.23 EMC95161.1 - 0.00013 21.6 0.1 0.2 11.4 0.0 3.1 3 0 0 3 3 3 2 CBS domain Phage_XkdX PF09693.5 EMC95161.1 - 0.042 13.3 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Mito_carr PF00153.22 EMC95162.1 - 1e-43 146.9 6.4 2.8e-15 55.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3602 PF12223.3 EMC95163.1 - 1.1e-10 41.7 15.0 8e-06 26.1 5.0 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) LANC_like PF05147.8 EMC95165.1 - 2.3e-27 95.5 0.0 4.9e-27 94.4 0.0 1.5 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein Pec_lyase PF09492.5 EMC95165.1 - 0.017 14.3 0.0 0.053 12.6 0.0 1.7 1 1 0 1 1 1 0 Pectic acid lyase SNARE PF05739.14 EMC95166.1 - 2.5e-06 27.0 5.4 2.5e-06 27.0 3.8 2.1 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 EMC95166.1 - 0.27 11.3 8.9 0.54 10.3 0.6 3.1 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus HET PF06985.6 EMC95167.1 - 4.4e-25 88.4 0.0 5.1e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1295 PF06966.7 EMC95168.1 - 4.6e-53 179.9 1.2 7.8e-53 179.1 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EMC95168.1 - 1.6e-07 31.1 3.1 2.2e-06 27.5 0.0 3.0 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EMC95168.1 - 3.1e-05 24.0 0.1 3.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EMC95168.1 - 0.00017 21.6 0.4 0.0029 17.6 0.1 2.7 1 1 1 2 2 2 1 Phospholipid methyltransferase PepX_N PF09168.5 EMC95168.1 - 0.05 13.8 0.1 0.082 13.1 0.1 1.3 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal DUF3807 PF12720.2 EMC95169.1 - 1.5e-27 96.8 2.6 2.2e-27 96.3 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) PepSY PF03413.14 EMC95169.1 - 0.012 16.1 0.1 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain VRR_NUC PF08774.6 EMC95171.1 - 7.2e-17 61.2 0.0 1.8e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Fasciclin PF02469.17 EMC95172.1 - 0.037 14.0 0.0 0.055 13.4 0.0 1.5 1 1 0 1 1 1 0 Fasciclin domain COPIIcoated_ERV PF07970.7 EMC95173.1 - 5.1e-70 235.5 0.0 6.4e-46 156.7 0.0 2.5 3 0 0 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMC95173.1 - 9.7e-34 115.2 0.0 4e-33 113.2 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2417 PF10329.4 EMC95174.1 - 5.1e-87 291.1 0.1 6.8e-87 290.7 0.0 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EMC95174.1 - 3.5e-07 30.3 0.2 9.5e-07 28.9 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family m04gp34like PF12216.3 EMC95174.1 - 0.061 12.6 0.3 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Immune evasion protein DUF3357 PF11837.3 EMC95174.1 - 0.07 12.9 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Abhydrolase_6 PF12697.2 EMC95175.1 - 1.1e-20 74.5 3.1 1.6e-20 74.0 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC95175.1 - 2.1e-10 40.5 0.0 5.1e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC95175.1 - 2.2e-06 27.3 0.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 EMC95175.1 - 0.01 16.1 3.3 0.067 13.3 2.3 2.4 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 EMC95175.1 - 0.018 14.6 0.2 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EMC95175.1 - 0.1 12.1 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Fcf1 PF04900.7 EMC95176.1 - 3.7e-22 78.3 0.1 6e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Fcf1 DUF726 PF05277.7 EMC95177.1 - 2.5e-120 401.4 3.5 3.5e-120 401.0 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EMC95177.1 - 0.0051 16.5 0.4 0.046 13.4 0.0 2.4 1 1 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 EMC95178.1 - 6.9e-20 71.3 0.0 1e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC95178.1 - 3.7e-05 22.8 0.6 0.003 16.5 0.2 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC95178.1 - 5.2e-05 23.5 0.3 0.022 15.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC95178.1 - 0.00025 20.9 0.1 0.00063 19.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC95178.1 - 0.00055 19.8 0.1 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC95178.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMC95178.1 - 0.025 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 EMC95178.1 - 0.028 13.2 0.3 0.05 12.4 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EMC95178.1 - 0.073 11.9 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMC95178.1 - 0.096 11.5 0.5 0.2 10.5 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EMC95178.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1232 PF06803.7 EMC95178.1 - 2.9 7.3 5.0 3.2 7.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1232) Myb_DNA-binding PF00249.26 EMC95179.1 - 2e-06 27.7 0.4 3.8e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC95179.1 - 3.5e-05 23.8 0.1 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMC95180.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC95180.1 - 0.0089 16.1 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SPX PF03105.14 EMC95181.1 - 0.011 15.5 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 SPX domain SAE2 PF08573.5 EMC95181.1 - 0.027 15.1 0.1 0.086 13.5 0.1 1.9 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Calcipressin PF04847.7 EMC95182.1 - 2e-39 135.1 0.3 3.5e-39 134.2 0.2 1.4 1 1 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 EMC95182.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 zf-RING_UBOX PF13445.1 EMC95183.1 - 0.1 12.3 1.1 0.18 11.5 0.7 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Utp12 PF04003.7 EMC95186.1 - 2.8e-22 78.6 0.0 3.9e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family CENP-T PF15511.1 EMC95186.1 - 0.23 10.6 36.6 0.018 14.2 21.7 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Bromodomain PF00439.20 EMC95187.1 - 2.3e-40 136.4 0.2 5.6e-19 67.8 0.0 2.1 2 0 0 2 2 2 2 Bromodomain DUF1194 PF06707.6 EMC95188.1 - 0.0049 15.8 0.0 0.0056 15.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) AMP-binding PF00501.23 EMC95189.1 - 2.2e-57 194.3 0.0 3.2e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EMC95189.1 - 1.3e-09 37.3 0.6 2.2e-09 36.6 0.4 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 EMC95189.1 - 4.4e-06 27.5 0.0 1.2e-05 26.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EMC95189.1 - 5e-05 23.4 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RNase_P_p30 PF01876.11 EMC95190.1 - 6.7e-48 161.7 0.0 9.3e-48 161.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Fungal_trans PF04082.13 EMC95191.1 - 7.1e-26 90.6 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC95191.1 - 0.0021 17.9 10.6 0.0041 17.0 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 EMC95192.1 - 2.4e-26 92.9 0.0 3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.1 EMC95192.1 - 0.029 14.8 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 GFA PF04828.9 EMC95193.1 - 3.3e-17 62.2 0.6 5.3e-17 61.5 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cupin_2 PF07883.6 EMC95194.1 - 2.6e-10 39.6 0.4 3.8e-10 39.1 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EMC95194.1 - 0.00022 20.7 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EMC95194.1 - 0.00036 20.2 0.1 0.00047 19.8 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMC95194.1 - 0.03 13.6 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMC95194.1 - 0.24 11.0 1.0 0.37 10.4 0.7 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Mannosyl_trans3 PF11051.3 EMC95196.1 - 1.7e-54 185.0 0.0 5.8e-54 183.2 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative DUF3106 PF11304.3 EMC95197.1 - 0.067 13.6 0.3 0.1 13.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) SBP_bac_7 PF03480.8 EMC95197.1 - 0.08 12.0 0.1 0.13 11.3 0.1 1.4 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Methyltransf_25 PF13649.1 EMC95198.1 - 1.8e-08 34.6 0.1 2.1e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC95198.1 - 6e-06 25.9 0.0 7.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC95198.1 - 1.6e-05 25.2 0.1 3.3e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC95198.1 - 0.0004 20.8 0.0 0.00071 20.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC95198.1 - 0.00052 19.7 0.0 0.0006 19.5 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC95198.1 - 0.0022 18.5 0.0 0.0028 18.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC95198.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase COesterase PF00135.23 EMC95199.1 - 7.3e-91 305.4 0.0 9.4e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC95199.1 - 6.8e-07 29.0 0.1 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.27 EMC95200.1 - 2.7e-25 87.2 13.0 1.2e-07 31.3 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC95200.1 - 9.6e-05 21.2 0.1 0.2 10.3 0.0 2.8 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EMC95200.1 - 0.0011 17.2 4.0 0.056 11.5 0.1 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EMC95200.1 - 0.075 11.2 0.0 0.13 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) RRF PF01765.14 EMC95201.1 - 3.3e-35 121.0 1.6 4.6e-35 120.5 1.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DUF2540 PF10802.3 EMC95201.1 - 0.062 12.9 0.0 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) TFIIS_M PF07500.9 EMC95202.1 - 7.7e-26 90.4 0.9 1.7e-25 89.3 0.6 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EMC95202.1 - 8.9e-18 63.6 9.7 1.6e-17 62.8 6.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EMC95202.1 - 2.3e-13 49.4 0.3 4.8e-13 48.3 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 EMC95202.1 - 1.2 8.5 4.3 3.8 6.9 3.0 1.8 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Tox-URI2 PF15653.1 EMC95202.1 - 2 8.6 5.3 11 6.3 0.1 2.4 2 0 0 2 2 2 0 URI fold toxin 2 zf-B_box PF00643.19 EMC95203.1 - 0.034 14.0 4.0 0.052 13.4 2.7 1.2 1 0 0 1 1 1 0 B-box zinc finger MFS_1 PF07690.11 EMC95205.1 - 8.4e-28 97.0 31.6 8.4e-28 97.0 21.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Tannase PF07519.6 EMC95206.1 - 4.7e-85 286.0 2.0 7e-85 285.5 1.4 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EMC95206.1 - 0.0001 22.2 0.1 0.00028 20.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC95206.1 - 0.00011 21.8 0.5 0.00026 20.6 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC95206.1 - 0.00038 19.7 0.5 0.095 11.9 0.3 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1446 PF07287.6 EMC95207.1 - 9.7e-125 415.7 0.2 1.2e-124 415.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Sec66 PF09802.4 EMC95208.1 - 2.9e-70 235.5 0.7 3.3e-70 235.3 0.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3050 PF11251.3 EMC95208.1 - 0.0024 17.1 0.2 0.012 14.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3050) ApoA-II PF04711.8 EMC95208.1 - 0.11 12.3 0.1 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) NPL4 PF05021.10 EMC95209.1 - 2.1e-122 408.0 0.0 2.8e-122 407.7 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EMC95209.1 - 7e-74 246.3 0.6 1e-73 245.8 0.4 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Sel1 PF08238.7 EMC95210.1 - 7.6e-14 51.8 16.8 6.2e-05 23.5 1.5 4.4 4 0 0 4 4 4 3 Sel1 repeat TRAPPC-Trs85 PF12739.2 EMC95210.1 - 0.081 11.5 0.1 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Pkinase PF00069.20 EMC95211.1 - 2.3e-55 187.5 0.0 2.9e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC95211.1 - 1.8e-35 122.2 0.0 2.4e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC95211.1 - 1e-08 34.5 0.0 2.1e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like PGP_phosphatase PF09419.5 EMC95211.1 - 0.058 12.7 0.1 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase RRN3 PF05327.6 EMC95214.1 - 4.7e-144 480.6 0.0 6.1e-144 480.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DnaJ PF00226.26 EMC95216.1 - 5.1e-27 93.4 0.9 1.3e-26 92.0 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMC95216.1 - 2e-23 82.0 0.1 2.7e-19 68.8 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMC95216.1 - 1.5e-14 53.7 19.6 2.8e-14 52.9 13.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EMC95216.1 - 0.085 12.5 11.3 0.13 11.9 2.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 EMC95216.1 - 0.26 11.0 6.2 4.6 7.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zinc-ribbons_6 PF07191.7 EMC95216.1 - 0.49 10.2 7.9 3.7 7.4 1.7 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 EMC95216.1 - 1.1 9.3 5.9 28 4.8 0.1 3.8 4 0 0 4 4 4 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 EMC95216.1 - 8 6.3 10.2 13 5.6 1.8 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF1674 PF07896.7 EMC95217.1 - 5.8e-17 61.6 3.3 1.4e-16 60.4 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) ORC6 PF05460.8 EMC95217.1 - 0.028 13.5 0.9 0.031 13.3 0.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HAUS4 PF14735.1 EMC95218.1 - 3.3e-10 39.6 6.6 5e-10 39.0 4.6 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 Nic96 PF04097.9 EMC95218.1 - 0.0051 15.0 4.5 0.0065 14.6 3.1 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TRAPPC-Trs85 PF12739.2 EMC95218.1 - 0.021 13.4 2.3 0.034 12.8 0.2 1.9 1 1 1 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit YcbB PF08664.5 EMC95218.1 - 0.033 13.9 3.8 0.052 13.3 1.5 1.9 1 1 1 2 2 2 0 YcbB domain Vac_Fusion PF02346.11 EMC95218.1 - 0.097 12.1 0.9 0.52 9.7 0.1 2.6 2 0 0 2 2 2 0 Chordopoxvirus fusion protein TarH PF02203.10 EMC95218.1 - 0.94 9.2 14.0 2.1 8.1 4.2 2.6 1 1 2 3 3 3 0 Tar ligand binding domain homologue Med9 PF07544.8 EMC95218.1 - 1.9 8.2 8.9 5.9 6.7 0.2 3.8 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MbeB_N PF04837.7 EMC95218.1 - 6.8 6.8 7.0 87 3.3 0.0 4.0 4 0 0 4 4 4 0 MbeB-like, N-term conserved region DUF2407_C PF13373.1 EMC95219.1 - 4e-39 133.7 0.0 5.9e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EMC95219.1 - 6.2e-25 87.2 0.0 1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EMC95219.1 - 1.7e-06 27.3 0.0 3.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EMC95219.1 - 0.046 13.5 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Dabb PF07876.7 EMC95220.1 - 5.9e-24 84.3 0.0 6.5e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fe-S_biosyn PF01521.15 EMC95221.1 - 1.1e-19 70.4 0.0 1.4e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis TIP49 PF06068.8 EMC95222.1 - 5.4e-176 585.1 0.0 6.3e-176 584.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EMC95222.1 - 7.8e-12 45.5 0.1 3e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMC95222.1 - 3.8e-10 39.2 0.1 3.2e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMC95222.1 - 1.7e-05 24.8 0.0 0.00029 20.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EMC95222.1 - 4.1e-05 23.2 0.1 0.00012 21.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EMC95222.1 - 6.6e-05 23.0 0.1 0.34 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMC95222.1 - 0.00036 20.2 0.2 0.07 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMC95222.1 - 0.0011 18.0 0.8 0.0029 16.7 0.3 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EMC95222.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EMC95222.1 - 0.0019 17.7 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 EMC95222.1 - 0.0032 17.4 0.1 0.0058 16.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMC95222.1 - 0.0056 15.8 0.2 0.26 10.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EMC95222.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EMC95222.1 - 0.018 14.4 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EMC95222.1 - 0.045 14.5 0.0 0.11 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC95222.1 - 0.056 13.7 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EMC95222.1 - 0.06 12.4 0.1 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 KaiC T2SE PF00437.15 EMC95222.1 - 0.075 11.9 0.4 0.28 10.0 0.1 1.9 1 1 1 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EMC95222.1 - 0.085 12.3 0.5 13 5.1 0.6 2.4 2 1 0 2 2 2 0 FtsK/SpoIIIE family DnaB_C PF03796.10 EMC95222.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Chitin_synth_2 PF03142.10 EMC95223.1 - 1.7e-290 963.9 0.2 8.3e-290 961.6 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EMC95223.1 - 4.6e-17 62.3 0.3 1.6e-16 60.6 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC95223.1 - 7.4e-15 55.3 0.0 2.6e-13 50.3 0.0 2.6 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EMC95223.1 - 1.2e-09 37.8 0.1 2.3e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EMC95223.1 - 0.00012 21.4 0.0 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMC95223.1 - 0.0032 17.1 0.0 0.058 13.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.7 EMC95225.1 - 1.7e-32 111.0 25.7 0.00035 21.1 0.0 7.4 6 1 1 7 7 7 7 Sel1 repeat WD40 PF00400.27 EMC95228.1 - 2.1e-06 27.3 6.0 5.3e-05 22.9 0.1 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Exotox-A_target PF09102.5 EMC95228.1 - 0.0023 17.4 0.1 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 Exotoxin A, targeting Atg14 PF10186.4 EMC95229.1 - 1.8e-54 184.7 0.0 2.1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 GRA6 PF05084.8 EMC95229.1 - 0.0029 17.1 1.4 0.0052 16.3 1.0 1.4 1 0 0 1 1 1 1 Granule antigen protein (GRA6) RasGAP_C PF03836.10 EMC95229.1 - 0.0078 15.9 0.2 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 RasGAP C-terminus Mnd1 PF03962.10 EMC95229.1 - 0.16 11.6 2.2 0.24 11.0 1.5 1.2 1 0 0 1 1 1 0 Mnd1 family AAA PF00004.24 EMC95233.1 - 1.3e-39 135.4 0.0 2.1e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC95233.1 - 5e-06 26.6 0.0 0.00048 20.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC95233.1 - 6.7e-06 26.2 0.4 0.00097 19.1 0.0 3.0 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EMC95233.1 - 4.4e-05 22.6 0.0 7.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMC95233.1 - 0.00021 22.0 0.4 0.00087 20.1 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC95233.1 - 0.00035 20.3 0.1 0.0012 18.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EMC95233.1 - 0.0004 19.2 0.1 0.00066 18.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EMC95233.1 - 0.00068 19.3 0.1 0.0026 17.4 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EMC95233.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC95233.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMC95233.1 - 0.0025 17.8 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMC95233.1 - 0.0028 17.1 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EMC95233.1 - 0.0039 17.3 0.1 0.011 15.8 0.0 1.8 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.16 EMC95233.1 - 0.0043 16.2 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EMC95233.1 - 0.0071 16.2 0.0 0.025 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMC95233.1 - 0.0081 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EMC95233.1 - 0.0088 15.4 0.4 0.31 10.4 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC95233.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMC95233.1 - 0.013 15.1 0.4 0.43 10.2 0.0 2.3 2 1 1 3 3 2 0 Archaeal ATPase AAA_24 PF13479.1 EMC95233.1 - 0.015 14.9 0.3 0.035 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMC95233.1 - 0.023 14.1 0.1 3.5 6.9 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain AAA_11 PF13086.1 EMC95233.1 - 0.03 13.9 0.0 0.061 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EMC95233.1 - 0.032 14.2 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EMC95233.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NTPase Taxilin PF09728.4 EMC95233.1 - 0.05 12.6 0.1 0.17 10.9 0.1 1.7 2 0 0 2 2 2 0 Myosin-like coiled-coil protein PhoH PF02562.11 EMC95233.1 - 0.051 12.7 0.2 0.11 11.7 0.2 1.4 1 1 0 1 1 1 0 PhoH-like protein SHQ1 PF04925.10 EMC95233.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 SHQ1 protein NB-ARC PF00931.17 EMC95233.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IPT PF01745.11 EMC95233.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase ABC_tran PF00005.22 EMC95233.1 - 0.086 13.1 0.0 0.18 12.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EMC95233.1 - 0.1 11.7 0.1 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.12 EMC95233.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 EMC95233.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Zot PF05707.7 EMC95233.1 - 0.11 11.9 0.1 4.6 6.6 0.1 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Nfu_N PF08712.6 EMC95234.1 - 7.6e-27 92.7 0.0 1e-25 89.1 0.0 2.2 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EMC95234.1 - 3.7e-22 77.8 0.1 6.4e-22 77.1 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain DUF4050 PF13259.1 EMC95236.1 - 3.4e-30 104.4 0.8 7.9e-30 103.2 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Peptidase_S8 PF00082.17 EMC95237.1 - 1.2e-51 175.5 1.4 1.2e-51 175.5 1.0 1.8 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EMC95237.1 - 1.7e-29 101.4 2.2 3.4e-29 100.4 1.5 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF1361 PF07099.6 EMC95237.1 - 0.092 12.5 0.3 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) PhoD PF09423.5 EMC95238.1 - 9e-08 31.0 0.1 2.3e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase tRNA-synt_1 PF00133.17 EMC95239.1 - 6.8e-41 139.9 0.0 7.6e-31 106.7 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMC95239.1 - 2.3e-17 62.7 0.9 5.8e-11 41.6 0.0 3.0 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMC95239.1 - 8.2e-12 45.1 0.1 2.5e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EMC95239.1 - 8.7e-08 31.6 0.0 1.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain p450 PF00067.17 EMC95242.1 - 2.5e-25 88.9 0.0 4.8e-25 88.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 GNAT_acetyltr_2 PF13718.1 EMC95243.1 - 1.1e-80 269.6 0.0 1.9e-80 268.8 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EMC95243.1 - 1.6e-66 223.2 0.0 2e-65 219.7 0.0 2.6 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EMC95243.1 - 1.9e-39 133.2 0.0 5e-39 131.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EMC95243.1 - 2.3e-31 107.8 0.2 7.6e-31 106.2 0.1 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EMC95243.1 - 1.5e-05 25.1 0.0 6.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC95243.1 - 0.041 13.9 0.0 0.35 10.9 0.0 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family PP2C_2 PF13672.1 EMC95244.1 - 9.3e-06 25.1 0.0 1.6e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMC95244.1 - 0.00024 20.8 0.1 0.00069 19.3 0.1 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EMC95244.1 - 0.0028 17.0 0.0 0.55 9.5 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C Ctr PF04145.10 EMC95245.1 - 7.2e-18 65.0 4.3 1.3e-16 60.8 3.0 1.9 1 1 0 1 1 1 1 Ctr copper transporter family UPF0104 PF03706.8 EMC95245.1 - 0.0037 16.5 0.3 0.0037 16.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF2238 PF09997.4 EMC95245.1 - 0.049 13.0 0.1 0.071 12.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) DUF4381 PF14316.1 EMC95245.1 - 0.059 13.4 0.5 0.071 13.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ORC3_N PF07034.6 EMC95246.1 - 2.5e-30 105.5 0.0 9.6e-30 103.6 0.0 1.9 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF3844 PF12955.2 EMC95248.1 - 1.3e-30 105.5 2.7 3.5e-30 104.1 2.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) Sugar_tr PF00083.19 EMC95249.1 - 1.2e-79 268.0 20.5 1.4e-79 267.8 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC95249.1 - 1.2e-12 47.2 33.5 1e-09 37.5 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EMC95249.1 - 0.015 13.8 20.5 0.026 13.0 7.6 2.4 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like DUF2857 PF11198.3 EMC95250.1 - 0.059 12.8 0.1 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) PX PF00787.19 EMC95251.1 - 1.5e-18 66.6 0.9 6.8e-18 64.5 0.1 2.2 2 1 0 2 2 2 1 PX domain Vps5 PF09325.5 EMC95251.1 - 3.1e-12 46.2 9.9 3.5e-06 26.4 0.5 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EMC95251.1 - 1.6e-06 27.8 3.9 3.5e-06 26.7 2.7 1.5 1 1 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.4 EMC95251.1 - 0.0077 15.5 0.4 0.76 8.9 0.1 2.2 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein RmuC PF02646.11 EMC95251.1 - 0.016 14.0 1.9 0.022 13.6 0.0 2.0 2 0 0 2 2 2 0 RmuC family APG6 PF04111.7 EMC95251.1 - 0.15 11.0 5.8 2.6 7.0 1.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 EMC95251.1 - 0.33 10.8 8.3 1.3 8.8 1.2 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EMC95251.1 - 3.9 5.2 5.6 3.7 5.2 1.0 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EMC95251.1 - 7 6.1 7.4 2.6 7.5 0.1 2.3 1 1 1 2 2 2 0 IncA protein DUF4404 PF14357.1 EMC95251.1 - 8.2 6.9 7.3 8.1 6.9 1.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) CDC37_N PF03234.9 EMC95252.1 - 0.019 15.3 12.1 3.9 7.7 6.4 2.6 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding Baculo_PEP_C PF04513.7 EMC95252.1 - 0.043 13.6 5.0 1 9.2 0.1 2.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YvfG PF09628.5 EMC95252.1 - 0.059 13.5 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 YvfG protein Mnd1 PF03962.10 EMC95252.1 - 0.33 10.5 19.1 0.02 14.5 4.1 2.3 1 1 1 2 2 2 0 Mnd1 family NPV_P10 PF05531.7 EMC95252.1 - 0.35 11.1 9.0 4.7 7.5 0.3 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.6 EMC95252.1 - 0.38 10.0 2.9 0.44 9.8 1.2 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein AAA_13 PF13166.1 EMC95252.1 - 0.48 8.8 13.3 0.83 8.0 9.2 1.3 1 0 0 1 1 1 0 AAA domain DUF2205 PF10224.4 EMC95252.1 - 0.99 9.0 10.6 0.56 9.8 0.1 3.5 2 2 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) Reo_sigmaC PF04582.7 EMC95252.1 - 1.9 7.5 4.8 2.2 7.3 1.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Syntaxin PF00804.20 EMC95252.1 - 7.8 6.7 10.9 17 5.6 0.1 3.1 1 1 1 2 2 2 0 Syntaxin Helicase_C PF00271.26 EMC95253.1 - 4.7e-27 93.6 0.3 2.9e-26 91.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC95253.1 - 2e-21 76.2 0.1 5.7e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase CMS1 PF14617.1 EMC95253.1 - 0.0062 15.6 0.2 0.017 14.2 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit CobA_CobO_BtuR PF02572.10 EMC95253.1 - 0.024 14.2 0.1 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 EMC95253.1 - 0.064 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Cupin_8 PF13621.1 EMC95254.1 - 1.7e-16 60.5 0.0 1.5e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EMC95254.1 - 2.8e-10 40.4 0.0 4.7e-09 36.4 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase tRNA-synt_2c PF01411.14 EMC95255.1 - 8.9e-215 714.1 0.5 1.4e-214 713.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) FAA_hydrolase PF01557.13 EMC95255.1 - 5.6e-46 156.7 0.0 1.3e-45 155.5 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family tRNA_SAD PF07973.9 EMC95255.1 - 7.7e-18 64.1 0.7 2e-17 62.8 0.5 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EMC95255.1 - 1.7e-06 27.5 3.1 4.7e-06 26.2 2.2 1.8 1 0 0 1 1 1 1 DHHA1 domain DUF4628 PF15429.1 EMC95256.1 - 0.11 11.9 0.3 0.18 11.1 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4628) DUF605 PF04652.11 EMC95257.1 - 0.72 9.1 27.5 1 8.6 19.1 1.2 1 0 0 1 1 1 0 Vta1 like Epimerase PF01370.16 EMC95258.1 - 6.6e-20 71.5 0.0 9.2e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC95258.1 - 9.8e-08 31.2 0.0 2.5e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMC95258.1 - 3.1e-06 26.2 0.0 5.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMC95258.1 - 1e-05 25.6 0.0 0.00016 21.7 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMC95258.1 - 3.9e-05 23.6 0.0 0.00017 21.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EMC95258.1 - 0.0017 17.1 0.0 0.2 10.3 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMC95258.1 - 0.0057 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EMC95258.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 EMC95258.1 - 0.035 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain BAH PF01426.13 EMC95259.1 - 1.5e-09 37.6 0.1 3.1e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H PF13771.1 EMC95259.1 - 0.00035 20.6 0.6 0.024 14.7 0.1 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.24 EMC95259.1 - 0.0017 18.0 0.4 0.0017 18.0 0.2 1.8 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.1 EMC95259.1 - 0.012 15.6 0.6 0.039 13.9 0.1 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 EMC95259.1 - 0.013 15.5 0.3 0.013 15.5 0.2 1.7 2 0 0 2 2 2 0 RING-like domain PH PF00169.24 EMC95260.1 - 0.00083 19.5 0.0 0.0061 16.7 0.0 2.3 2 0 0 2 2 2 1 PH domain zf-C2H2 PF00096.21 EMC95262.1 - 0.57 10.6 9.0 1.5 9.3 0.5 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type MRP_L53 PF10780.4 EMC95264.1 - 1.4e-09 37.7 0.3 2.5e-09 36.9 0.2 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF2442 PF10387.4 EMC95264.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) RTC4 PF14474.1 EMC95265.1 - 2e-24 85.8 0.0 3.7e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain DUF385 PF04075.9 EMC95265.1 - 0.008 16.1 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF385) ORC6 PF05460.8 EMC95265.1 - 3.4 6.6 8.3 5.5 5.9 5.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CKS PF01111.14 EMC95266.1 - 7e-37 125.0 1.7 8.7e-37 124.7 1.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1387 PF07139.6 EMC95267.1 - 0.074 12.6 3.0 0.21 11.1 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Pyrophosphatase PF00719.14 EMC95268.1 - 2.6e-53 179.6 0.1 3.4e-53 179.2 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DAD PF02109.11 EMC95269.1 - 7.3e-49 164.5 2.2 8.6e-49 164.3 1.6 1.0 1 0 0 1 1 1 1 DAD family DUF4534 PF15049.1 EMC95269.1 - 0.073 12.7 0.1 0.12 11.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4534) DUF2768 PF10966.3 EMC95269.1 - 0.19 11.9 1.6 3.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Tmemb_14 PF03647.8 EMC95270.1 - 3.9e-23 81.6 9.1 4.9e-23 81.3 6.3 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1275 PF06912.6 EMC95270.1 - 0.018 14.2 1.0 0.024 13.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF2416 PF10315.4 EMC95270.1 - 0.08 13.1 1.0 0.19 11.9 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) FtsL PF04999.8 EMC95271.1 - 0.00054 19.6 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Cell division protein FtsL 7TM_GPCR_Srd PF10317.4 EMC95271.1 - 0.073 12.0 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Ank_2 PF12796.2 EMC95272.1 - 1.6e-21 76.3 1.7 4.7e-08 33.2 0.3 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC95272.1 - 4.8e-13 48.1 0.5 4e-07 29.5 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EMC95272.1 - 7.3e-09 35.9 0.4 0.15 12.6 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC95272.1 - 2.6e-08 33.3 0.3 0.0018 18.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC95272.1 - 7.7e-07 29.1 0.0 0.016 15.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) CAP_GLY PF01302.20 EMC95273.1 - 4.1e-18 64.8 0.8 7.8e-18 63.9 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain zf-CCHC PF00098.18 EMC95273.1 - 0.062 13.2 0.4 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Filament PF00038.16 EMC95273.1 - 0.076 12.4 20.9 0.28 10.5 2.1 3.6 3 1 1 4 4 4 0 Intermediate filament protein IncA PF04156.9 EMC95273.1 - 0.27 10.8 27.5 0.56 9.7 8.6 3.7 2 1 0 3 3 3 0 IncA protein COG2 PF06148.6 EMC95273.1 - 0.31 10.9 9.0 1.7 8.5 0.2 3.8 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 EMC95273.1 - 0.52 10.3 17.0 0.045 13.7 0.6 3.6 3 2 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CCDC144C PF14915.1 EMC95273.1 - 0.54 9.1 14.4 0.79 8.5 0.6 3.4 4 1 0 4 4 4 0 CCDC144C protein coiled-coil region zf-CCHC_2 PF13696.1 EMC95273.1 - 0.73 9.3 4.4 0.53 9.8 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle DivIC PF04977.10 EMC95273.1 - 1.4 8.4 24.9 0.21 11.1 0.5 5.1 5 0 0 5 5 5 0 Septum formation initiator NPV_P10 PF05531.7 EMC95273.1 - 5.1 7.4 7.1 4.1 7.7 0.0 3.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EMC95273.1 - 5.4 6.7 27.8 0.036 13.8 3.9 4.2 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein DUF2353 PF09789.4 EMC95273.1 - 5.5 6.1 21.3 8.9 5.4 5.1 2.8 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) AAA_13 PF13166.1 EMC95273.1 - 6.5 5.0 9.6 1 7.7 1.7 2.1 1 1 2 3 3 3 0 AAA domain zf-CCCH PF00642.19 EMC95274.1 - 2.8e-21 74.6 34.2 1.9e-06 27.4 0.3 5.1 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1771 PF08590.5 EMC95275.1 - 6.6e-13 48.4 10.0 6.6e-13 48.4 6.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EMC95275.1 - 8.8e-11 41.8 0.0 4.1e-10 39.7 0.0 2.2 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EMC95275.1 - 2.7e-08 33.2 4.8 0.00029 20.4 0.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 EMC95275.1 - 0.12 11.8 0.2 0.59 9.6 0.1 2.2 2 0 0 2 2 2 0 CUE domain Scm3 PF10384.4 EMC95277.1 - 2.3e-22 78.2 0.4 6.9e-22 76.6 0.3 1.9 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-binding PF00249.26 EMC95277.1 - 2.4e-17 62.7 0.4 0.004 17.1 0.0 5.3 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC95277.1 - 9.6e-17 60.8 0.9 0.0042 17.1 0.1 5.4 5 0 0 5 5 5 4 Myb-like DNA-binding domain GATA PF00320.22 EMC95277.1 - 1e-10 40.7 3.9 1.8e-10 39.9 2.7 1.4 1 0 0 1 1 1 1 GATA zinc finger Sigma70_r4_2 PF08281.7 EMC95277.1 - 0.00017 20.9 0.0 0.093 12.2 0.1 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 Myb_DNA-bind_2 PF08914.6 EMC95277.1 - 0.0013 18.4 1.9 0.078 12.7 0.4 3.7 3 1 0 3 3 3 1 Rap1 Myb domain HTH_20 PF12840.2 EMC95277.1 - 0.0021 17.8 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.1 EMC95277.1 - 0.018 14.6 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain COX4 PF02936.9 EMC95277.1 - 0.094 12.4 1.3 7.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV APG6 PF04111.7 EMC95278.1 - 3.7e-109 364.5 0.1 4.8e-109 364.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 EMC95278.1 - 0.011 13.6 3.9 0.014 13.2 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 EMC95278.1 - 0.021 15.1 8.5 0.021 15.1 5.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EMC95278.1 - 0.032 14.5 3.9 0.038 14.3 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) zf-C4H2 PF10146.4 EMC95278.1 - 0.11 12.4 11.1 0.37 10.7 7.3 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein FUSC PF04632.7 EMC95278.1 - 0.12 10.7 4.2 0.16 10.3 2.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HrpA_pilin PF09589.5 EMC95278.1 - 0.18 12.2 2.0 0.61 10.5 1.4 2.1 1 1 0 1 1 1 0 HrpA pilus formation protein AAA_13 PF13166.1 EMC95278.1 - 0.25 9.7 7.0 0.32 9.3 4.8 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 EMC95278.1 - 0.34 10.7 18.1 0.81 9.5 11.9 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.10 EMC95278.1 - 0.5 9.9 16.8 3.3 7.3 11.6 2.1 1 1 0 1 1 1 0 Mnd1 family DUF3450 PF11932.3 EMC95278.1 - 0.54 9.4 13.5 0.94 8.6 9.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ERM PF00769.14 EMC95278.1 - 0.78 9.2 20.8 1.5 8.2 14.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.4 EMC95278.1 - 5.5 5.8 13.0 89 1.8 9.2 2.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EMC95278.1 - 9.2 4.5 10.5 5.3 5.3 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) GAS PF13851.1 EMC95278.1 - 9.3 5.3 19.5 0.43 9.7 4.1 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding adh_short PF00106.20 EMC95279.1 - 2.4e-13 50.3 0.1 1e-12 48.2 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC95279.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC95279.1 - 0.00094 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMC95279.1 - 0.0026 17.4 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 KR domain LSM PF01423.17 EMC95280.1 - 1.9e-20 72.1 0.2 2.1e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain APH PF01636.18 EMC95281.1 - 1.9e-39 135.8 0.0 2.8e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMC95281.1 - 4.2e-07 29.4 0.0 1.1e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EMC95281.1 - 2.7e-05 23.8 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMC95281.1 - 0.0074 15.6 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 RIO1 family DUF2059 PF09832.4 EMC95281.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) DUF1679 PF07914.6 EMC95281.1 - 0.094 11.3 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.9 EMC95281.1 - 0.11 11.4 0.0 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_28 PF02636.12 EMC95282.1 - 6.3e-36 124.0 0.0 1.4e-35 122.9 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EMC95282.1 - 0.062 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PALP PF00291.20 EMC95283.1 - 2.5e-54 184.6 0.9 3.1e-54 184.2 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhomboid PF01694.17 EMC95283.1 - 1.6 8.7 4.7 1.6 8.7 0.0 2.6 3 0 0 3 3 3 0 Rhomboid family zf-H2C2_2 PF13465.1 EMC95286.1 - 8.2e-11 41.6 14.5 1.2e-05 25.3 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC95286.1 - 1.7e-10 40.6 11.3 9.7e-06 25.6 3.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC95286.1 - 2e-07 30.8 9.2 0.00011 22.3 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EMC95286.1 - 6.5e-06 26.1 1.3 1.9e-05 24.6 0.9 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC95286.1 - 5.9e-05 23.0 5.2 0.0001 22.3 1.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC95286.1 - 0.00037 20.2 6.7 0.0071 16.2 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC95286.1 - 0.11 12.6 2.6 0.11 12.5 1.0 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EMC95286.1 - 0.38 10.4 4.0 7.3 6.3 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EMC95286.1 - 0.97 9.2 5.8 0.44 10.3 1.2 2.2 1 1 1 2 2 2 0 BED zinc finger Epimerase PF01370.16 EMC95287.1 - 2.2e-56 190.9 0.0 2.6e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC95287.1 - 1.2e-22 80.2 0.0 9.1e-22 77.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EMC95287.1 - 4.6e-19 68.3 0.0 2.5e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EMC95287.1 - 6.1e-18 64.5 0.0 7.8e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMC95287.1 - 1.8e-17 63.1 0.0 2.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMC95287.1 - 2e-07 31.1 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMC95287.1 - 0.0051 16.7 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase TPT PF03151.11 EMC95288.1 - 9.3e-16 57.8 9.1 9.3e-16 57.8 6.3 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMC95288.1 - 6.8e-08 31.7 12.2 8.8e-08 31.4 8.4 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMC95288.1 - 0.00032 20.7 19.8 0.0061 16.5 3.5 2.7 2 1 0 2 2 2 2 EamA-like transporter family DUF4267 PF14087.1 EMC95288.1 - 0.089 12.3 3.0 0.097 12.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) EmrE PF13536.1 EMC95288.1 - 7.4 6.8 22.7 3 8.0 4.0 3.1 3 1 0 3 3 3 0 Multidrug resistance efflux transporter RmlD_sub_bind PF04321.12 EMC95289.1 - 7.4e-14 51.3 0.0 1.2e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EMC95289.1 - 2.8e-12 46.6 0.0 4.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC95289.1 - 5.7e-06 25.4 0.0 9.1e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein WD40 PF00400.27 EMC95290.1 - 1e-06 28.3 0.7 0.022 14.6 0.2 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 EMC95290.1 - 0.00028 20.0 0.0 0.00056 19.0 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region Vps53_N PF04100.7 EMC95291.1 - 1.7e-107 359.5 2.5 1.7e-107 359.5 1.8 2.2 3 0 0 3 3 3 1 Vps53-like, N-terminal DUF2450 PF10475.4 EMC95291.1 - 2.4e-07 29.9 6.2 5e-07 28.9 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EMC95291.1 - 0.019 13.1 4.1 0.04 12.0 2.8 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF2451 PF10474.4 EMC95291.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.6 EMC95291.1 - 0.057 12.0 5.1 0.033 12.8 1.7 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Flagellin_N PF00669.15 EMC95291.1 - 0.51 10.1 6.7 0.31 10.8 0.6 2.8 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4164 PF13747.1 EMC95291.1 - 1.2 9.3 7.3 0.51 10.5 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) COG2 PF06148.6 EMC95291.1 - 3.3 7.6 10.8 0.24 11.2 1.0 3.5 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EMC95291.1 - 8.7 6.1 9.3 0.93 9.3 1.6 2.8 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Amino_oxidase PF01593.19 EMC95292.1 - 2e-87 294.1 0.1 9.5e-87 291.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EMC95292.1 - 3.2e-13 49.6 0.0 6.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EMC95292.1 - 4.5e-07 29.7 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EMC95292.1 - 2e-06 27.9 0.3 4.6e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC95292.1 - 0.0026 18.1 0.6 0.0065 16.8 0.4 1.7 1 0 0 1 1 1 1 HMG-box domain DAO PF01266.19 EMC95292.1 - 0.014 14.3 0.1 0.014 14.3 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC95292.1 - 0.034 13.9 1.5 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EMC95292.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EMC95292.1 - 0.06 13.2 0.3 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC95292.1 - 1.3 7.7 2.2 11 4.7 0.4 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF3542 PF12061.3 EMC95293.1 - 0.055 12.4 1.4 0.095 11.6 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3542) Kua-UEV1_localn PF10520.4 EMC95293.1 - 0.064 12.9 0.5 0.069 12.7 0.3 1.1 1 0 0 1 1 1 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF4294 PF14127.1 EMC95293.1 - 0.066 12.8 0.2 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) SPAM PF02090.10 EMC95293.1 - 0.081 12.9 2.6 0.38 10.7 1.8 1.9 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF4200 PF13863.1 EMC95293.1 - 4.8 7.1 8.6 2.1 8.2 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Pyr_redox_2 PF07992.9 EMC95294.1 - 5.8e-30 104.6 0.0 2e-29 102.9 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC95294.1 - 9.2e-16 58.0 0.1 1.1e-13 51.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC95294.1 - 1.4e-09 38.3 0.1 2e-07 31.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC95294.1 - 2.7e-06 26.6 0.1 0.0064 15.6 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EMC95294.1 - 5.8e-06 25.4 0.9 0.35 9.7 0.2 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMC95294.1 - 9.1e-06 25.0 0.7 9.6e-05 21.6 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EMC95294.1 - 2e-05 23.6 3.0 0.049 12.4 0.1 3.8 3 1 1 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.1 EMC95294.1 - 0.00023 20.2 0.1 0.014 14.3 0.0 2.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EMC95294.1 - 0.00053 18.5 0.2 0.031 12.7 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 EMC95294.1 - 0.0019 18.1 0.1 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EMC95294.1 - 0.0022 18.2 1.6 0.05 13.8 0.0 3.2 3 1 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EMC95294.1 - 0.014 15.4 0.2 0.32 11.1 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EMC95294.1 - 0.022 13.6 8.2 0.078 11.8 0.5 3.1 3 1 0 4 4 4 0 FAD binding domain Trp_halogenase PF04820.9 EMC95294.1 - 0.043 12.4 0.1 1.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase DUF1573 PF07610.6 EMC95296.1 - 0.55 9.8 4.2 0.97 9.0 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1573) Glyco_hydro_17 PF00332.13 EMC95298.1 - 0.0042 16.1 0.4 0.038 13.0 0.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 Pro_isomerase PF00160.16 EMC95299.1 - 5.4e-48 163.1 0.4 6e-48 162.9 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_transf_22 PF03901.12 EMC95300.1 - 2.7e-32 112.3 17.4 3.2e-32 112.0 12.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MFS_1 PF07690.11 EMC95301.1 - 2.1e-44 151.7 61.4 1.3e-42 145.7 42.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC95301.1 - 1e-24 86.6 18.1 1.7e-24 85.9 12.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC95301.1 - 1.7e-19 69.7 3.6 1.7e-19 69.7 2.5 3.9 3 1 1 4 4 4 2 Sugar (and other) transporter SOG2 PF10428.4 EMC95301.1 - 0.86 8.1 5.9 0.11 11.1 0.8 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein Fungal_trans PF04082.13 EMC95302.1 - 9e-23 80.4 0.2 2.2e-22 79.1 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC95302.1 - 1.9e-07 30.8 12.8 4.3e-07 29.7 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfate_transp PF00916.15 EMC95306.1 - 5.1e-76 255.3 8.7 5.1e-76 255.3 6.1 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMC95306.1 - 2.3e-30 104.1 3.9 2.3e-30 104.1 2.7 3.3 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMC95306.1 - 2.3e-06 27.0 0.0 4.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF457 PF04307.9 EMC95306.1 - 3.1 7.0 15.0 0.0091 15.3 2.7 2.4 3 0 0 3 3 3 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) RabGAP-TBC PF00566.13 EMC95307.1 - 1.7e-35 122.4 0.0 4.5e-27 94.9 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Dickkopf_N PF04706.7 EMC95309.1 - 0.025 14.7 5.5 0.044 13.9 3.8 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MHC_II_beta PF00969.14 EMC95310.1 - 0.09 12.7 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain ChaC PF04752.7 EMC95311.1 - 2.7e-55 187.0 0.0 3.8e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein Dynamin_N PF00350.18 EMC95312.1 - 5.8e-27 94.5 0.0 1.2e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EMC95312.1 - 3.9e-14 52.1 0.0 5.8e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EMC95312.1 - 0.001 19.0 0.0 0.0048 16.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC95312.1 - 0.045 14.2 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EMC95312.1 - 0.062 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UCH PF00443.24 EMC95315.1 - 1.9e-64 217.4 0.0 3.1e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC95315.1 - 4.4e-32 111.7 0.7 3.4e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EMC95315.1 - 0.00087 18.6 2.4 0.01 15.1 1.0 2.4 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF948 PF06103.6 EMC95315.1 - 0.2 11.5 0.1 0.47 10.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ycf1 PF05758.7 EMC95315.1 - 0.23 9.1 4.6 0.41 8.2 3.2 1.4 1 0 0 1 1 1 0 Ycf1 EF-hand_1 PF00036.27 EMC95316.1 - 3.2e-26 88.5 7.9 9e-08 30.8 0.2 5.1 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EMC95316.1 - 6.1e-22 75.4 5.2 0.00014 21.4 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EMC95316.1 - 2.7e-21 74.9 3.8 2.4e-12 46.2 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EMC95316.1 - 3e-21 75.3 5.1 9.4e-11 41.6 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC95316.1 - 1.1e-18 65.6 11.3 0.00021 20.4 0.0 4.7 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.2 EMC95316.1 - 0.021 14.5 0.4 0.83 9.4 0.0 2.6 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC95316.1 - 0.24 11.4 0.7 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_S13_N PF08069.7 EMC95318.1 - 6.5e-29 99.5 0.3 1.1e-28 98.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EMC95318.1 - 1.5e-22 79.1 0.0 2.2e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EMC95318.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain NfeD PF01957.13 EMC95319.1 - 0.9 9.6 0.0 0.9 9.6 0.0 5.2 4 2 0 5 5 5 0 NfeD-like C-terminal, partner-binding CPSF_A PF03178.10 EMC95320.1 - 3e-71 240.1 0.0 1.8e-70 237.5 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EMC95320.1 - 2.4e-08 32.5 0.1 1.1e-06 27.1 0.0 2.6 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term RRM_1 PF00076.17 EMC95324.1 - 5.1e-22 77.2 0.0 6.5e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95324.1 - 1.2e-16 60.4 0.0 1.5e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95324.1 - 1e-10 41.3 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RTC PF01137.16 EMC95325.1 - 2.2e-33 114.9 0.0 3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EMC95325.1 - 1.9e-29 101.6 0.0 3.6e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Rax2 PF12768.2 EMC95326.1 - 2e-62 210.9 8.7 4.2e-56 190.2 0.2 4.2 3 1 0 3 3 3 3 Cortical protein marker for cell polarity WD40 PF00400.27 EMC95327.1 - 3.2e-70 229.6 9.0 3.2e-08 33.1 0.0 11.3 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EMC95327.1 - 1.2e-12 47.6 0.0 2.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EMC95327.1 - 2.1e-05 23.4 0.1 1.2 7.8 0.0 5.2 1 1 4 5 5 5 2 Nup133 N terminal like Nup160 PF11715.3 EMC95327.1 - 0.00033 18.9 4.5 0.028 12.5 0.3 4.3 4 2 1 5 5 5 2 Nucleoporin Nup120/160 P34-Arc PF04045.9 EMC95328.1 - 1.1e-100 335.9 0.0 1.3e-100 335.6 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EMC95328.1 - 0.033 13.5 1.1 0.08 12.3 0.8 1.6 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.18 EMC95328.1 - 0.045 13.8 1.0 0.12 12.4 0.4 1.9 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Radical_SAM PF04055.16 EMC95328.1 - 0.071 13.2 0.1 0.36 10.9 0.1 2.0 1 1 0 2 2 2 0 Radical SAM superfamily Circo_capsid PF02443.10 EMC95329.1 - 0.16 11.2 1.4 0.19 11.0 1.0 1.1 1 0 0 1 1 1 0 Circovirus capsid protein PAF-AH_p_II PF03403.8 EMC95331.1 - 3.4e-39 134.2 0.0 4.2e-38 130.6 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMC95331.1 - 8.2e-14 51.5 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC95331.1 - 1.8e-08 34.5 0.1 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMC95331.1 - 4.3e-05 22.5 0.1 0.00037 19.4 0.0 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EMC95331.1 - 0.00038 20.2 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase PF07224.6 EMC95331.1 - 0.0035 16.1 0.0 0.0072 15.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase WD40_alt PF14077.1 EMC95331.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF3328 PF11807.3 EMC95332.1 - 2e-16 60.3 0.0 2.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Reprolysin_5 PF13688.1 EMC95333.1 - 2.1e-57 194.2 16.1 2.1e-57 194.2 11.1 3.1 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMC95333.1 - 1.3e-47 162.0 8.1 2.6e-47 161.0 5.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC95333.1 - 3e-43 147.8 10.0 3e-43 147.8 7.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EMC95333.1 - 7e-20 71.0 29.7 7e-20 71.0 20.6 5.3 3 2 2 5 5 5 1 Disintegrin Reprolysin_3 PF13582.1 EMC95333.1 - 1.5e-17 64.2 2.1 1.5e-17 64.2 1.5 2.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 EMC95333.1 - 0.015 15.0 0.0 0.049 13.4 0.0 1.8 2 0 0 2 2 2 0 Reprolysin family propeptide Exosortase_EpsH PF09721.5 EMC95333.1 - 0.27 10.4 0.2 0.51 9.4 0.1 1.3 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) Creatininase PF02633.9 EMC95334.1 - 0.031 13.3 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Creatinine amidohydrolase Cupin_2 PF07883.6 EMC95335.1 - 3.6e-07 29.5 0.0 1.1e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EMC95335.1 - 0.027 13.8 0.0 0.068 12.6 0.0 1.6 1 1 1 2 2 2 0 Cupin CtaG_Cox11 PF04442.9 EMC95336.1 - 9.1e-56 187.8 0.0 1.2e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 zf-HIT PF04438.11 EMC95337.1 - 7.7e-10 38.2 11.8 1.2e-09 37.6 8.2 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EMC95337.1 - 0.044 13.6 10.6 0.085 12.7 7.4 1.5 1 0 0 1 1 1 0 MYND finger RasGEF PF00617.14 EMC95338.1 - 1.1e-49 168.7 0.1 1.7e-49 168.1 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMC95338.1 - 5.4e-12 45.7 0.0 1.7e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif Miro PF08477.8 EMC95338.1 - 8.9e-11 42.3 0.0 2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EMC95338.1 - 1.6e-07 30.8 0.0 1.4e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.13 EMC95338.1 - 0.0075 15.7 0.5 0.15 11.5 0.0 2.9 3 1 0 3 3 3 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EMC95338.1 - 0.058 14.2 0.0 0.41 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2236 PF09995.4 EMC95340.1 - 4.6e-34 117.7 0.1 5.7e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Rxt3 PF08642.5 EMC95342.1 - 7.6e-23 80.9 0.0 1.5e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EMC95342.1 - 7.9e-06 25.7 0.0 7.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 LCCL domain Rgp1 PF08737.5 EMC95343.1 - 6.3e-98 328.5 0.0 9e-98 328.0 0.0 1.2 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EMC95343.1 - 0.0023 17.7 0.0 0.0091 15.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Neugrin PF06413.6 EMC95344.1 - 7.2e-09 35.7 0.3 7.2e-09 35.7 0.2 1.8 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 EMC95344.1 - 4.3e-07 30.0 1.1 4.3e-07 30.0 0.8 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Lge1 PF11488.3 EMC95344.1 - 0.092 12.9 1.4 0.41 10.8 0.1 2.5 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Ribonuclease_3 PF00636.21 EMC95345.1 - 4.9e-36 123.6 0.0 9e-19 68.0 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMC95345.1 - 2.8e-28 98.4 0.7 2e-13 50.3 0.1 3.9 3 1 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 EMC95345.1 - 1.2e-16 60.6 0.0 2.7e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 EMC95345.1 - 7e-16 57.7 0.0 1.8e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EMC95345.1 - 1.3e-13 50.6 0.1 3.6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC95345.1 - 7.8e-10 38.8 0.0 4.1e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMC95345.1 - 0.082 13.0 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain RINGv PF12906.2 EMC95346.1 - 4.5e-10 39.4 3.9 1.3e-09 37.9 0.6 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EMC95346.1 - 6.9e-05 22.5 4.6 0.00015 21.4 1.0 2.2 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.24 EMC95346.1 - 0.016 14.9 2.7 0.016 14.9 1.9 1.7 2 0 0 2 2 2 0 PHD-finger ABC2_membrane_2 PF12679.2 EMC95346.1 - 0.046 12.5 0.5 0.071 11.9 0.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1206 PF06724.6 EMC95346.1 - 7.2 6.4 8.9 0.34 10.7 0.5 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Proteasome PF00227.21 EMC95347.1 - 8.3e-56 188.2 0.1 1.4e-31 109.2 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EMC95347.1 - 1.8e-11 43.1 0.3 4.3e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RabGAP-TBC PF00566.13 EMC95348.1 - 7.6e-48 162.8 1.9 8.1e-47 159.4 0.2 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain HAP1_N PF04849.8 EMC95348.1 - 0.00045 19.2 16.9 0.00045 19.2 11.7 1.8 2 0 0 2 2 2 1 HAP1 N-terminal conserved region Lebercilin PF15619.1 EMC95348.1 - 3.2 7.1 29.6 1.8 7.9 15.9 2.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF972 PF06156.8 EMC95348.1 - 6.5 7.1 25.0 0.15 12.4 4.5 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF972) HALZ PF02183.13 EMC95348.1 - 7 6.4 19.8 0.34 10.6 1.5 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper FUSC PF04632.7 EMC95348.1 - 8.3 4.7 8.8 8.7 4.6 5.4 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 EMC95348.1 - 8.4 4.1 9.0 16 3.1 6.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Acetyltransf_3 PF13302.1 EMC95349.1 - 0.00018 21.7 0.1 0.0002 21.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BofC_C PF08955.5 EMC95351.1 - 0.08 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 BofC C-terminal domain Lipoprotein_8 PF02030.10 EMC95352.1 - 0.09 11.2 0.4 0.12 10.8 0.2 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Paf1 PF03985.8 EMC95352.1 - 0.62 8.7 3.3 0.85 8.2 2.3 1.1 1 0 0 1 1 1 0 Paf1 Cas_GSU0054 PF09609.5 EMC95353.1 - 0.047 12.5 0.1 0.048 12.4 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Rhodanese PF00581.15 EMC95358.1 - 1.7e-08 34.7 0.0 2.9e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain WLM PF08325.5 EMC95359.1 - 3.4e-49 167.2 0.0 4.4e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EMC95359.1 - 0.00023 20.1 18.1 0.00044 19.2 2.0 3.2 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others UIM PF02809.15 EMC95359.1 - 0.057 12.9 0.1 0.24 11.0 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif DZR PF12773.2 EMC95359.1 - 0.088 12.6 8.8 0.85 9.4 6.4 2.1 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_M54 PF07998.6 EMC95359.1 - 0.21 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF605 PF04652.11 EMC95359.1 - 0.57 9.5 8.7 0.82 8.9 6.0 1.2 1 0 0 1 1 1 0 Vta1 like OrfB_Zn_ribbon PF07282.6 EMC95359.1 - 8.6 6.1 7.6 2.4 7.8 1.1 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.10 EMC95359.1 - 9.2 5.9 14.2 0.34 10.5 1.5 3.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger HATPase_c PF02518.21 EMC95361.1 - 4e-30 103.7 0.1 8.4e-30 102.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMC95361.1 - 7.6e-23 80.6 0.1 2.3e-22 79.1 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMC95361.1 - 3.7e-21 74.8 0.7 3.8e-20 71.6 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EMC95361.1 - 5.5e-14 52.4 0.0 1.3e-06 28.6 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EMC95361.1 - 7e-13 48.4 0.8 1.8e-12 47.1 0.5 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EMC95361.1 - 1.7e-11 44.1 0.1 0.052 13.5 0.0 5.1 4 0 0 4 4 4 3 PAS fold PAS PF00989.19 EMC95361.1 - 8.7e-08 31.9 0.0 0.063 13.0 0.0 3.9 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 EMC95361.1 - 0.019 14.8 0.0 0.096 12.5 0.0 2.3 1 0 0 1 1 1 0 PAS domain O-FucT PF10250.4 EMC95362.1 - 1.1e-12 47.7 0.3 5.7e-11 42.1 0.2 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SNARE_assoc PF09335.6 EMC95363.1 - 4.8e-12 46.1 5.5 4.8e-12 46.1 3.8 2.6 2 1 2 4 4 4 1 SNARE associated Golgi protein UPF0154 PF03672.8 EMC95363.1 - 0.0064 16.0 4.1 0.16 11.6 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) DUF1049 PF06305.6 EMC95363.1 - 0.029 13.8 0.0 0.029 13.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF3552 PF12072.3 EMC95363.1 - 1.2 8.2 5.3 0.76 8.9 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF2401 PF10287.4 EMC95364.1 - 6e-85 284.4 0.1 9.7e-85 283.7 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EMC95364.1 - 2.7e-26 91.4 0.1 6.2e-26 90.3 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) RAP1 PF07218.6 EMC95364.1 - 3.4 5.6 9.3 4.5 5.2 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 EMC95364.1 - 7.3 4.7 5.5 9.1 4.4 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Peroxin-13_N PF04088.8 EMC95366.1 - 2.3e-58 196.6 0.1 3.8e-58 195.9 0.1 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EMC95366.1 - 4.8e-10 38.7 0.0 7.7e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC95366.1 - 7.1e-07 28.5 0.2 3.9e-06 26.1 0.2 2.0 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC95366.1 - 2.5e-06 26.9 0.1 4.8e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Dpy-30 PF05186.8 EMC95368.1 - 2.2e-13 49.4 0.7 4e-13 48.6 0.2 1.6 2 0 0 2 2 2 1 Dpy-30 motif TspO_MBR PF03073.10 EMC95370.1 - 0.011 15.2 4.4 0.022 14.2 3.1 1.6 1 1 0 1 1 1 0 TspO/MBR family DUF1129 PF06570.6 EMC95370.1 - 0.048 12.9 2.4 0.23 10.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) O-antigen_lig PF13425.1 EMC95370.1 - 0.15 12.0 9.2 0.81 9.6 4.5 2.7 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Spore_YhaL PF14147.1 EMC95370.1 - 0.16 11.4 0.1 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein YhaL AzlD PF05437.7 EMC95370.1 - 0.23 11.4 6.3 1.3 8.9 2.7 2.5 1 1 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DUF4191 PF13829.1 EMC95370.1 - 0.39 9.8 4.8 0.41 9.7 2.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF1427 PF07235.6 EMC95370.1 - 0.76 9.8 3.5 0.74 9.9 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) DUF1705 PF08019.7 EMC95370.1 - 3.5 7.1 7.3 12 5.3 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF1705) DUF3429 PF11911.3 EMC95370.1 - 3.6 7.5 10.4 1.5 8.8 4.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3429) YfhO PF09586.5 EMC95370.1 - 7.3 4.4 6.8 12 3.8 0.0 1.6 1 1 0 2 2 2 0 Bacterial membrane protein YfhO TAP_C PF03943.8 EMC95373.1 - 5.1e-10 38.6 0.2 8.5e-10 37.9 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EMC95373.1 - 3.2e-07 29.8 6.5 1.1e-05 24.8 2.2 2.8 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC95373.1 - 0.0022 17.7 1.1 0.65 10.2 0.2 3.4 3 0 0 3 3 3 1 Leucine Rich Repeat UBA_4 PF14555.1 EMC95373.1 - 0.0025 17.3 0.2 0.0088 15.5 0.1 2.0 1 0 0 1 1 1 1 UBA-like domain LRR_8 PF13855.1 EMC95373.1 - 0.0026 17.4 1.2 0.0062 16.2 0.8 1.7 1 0 0 1 1 1 1 Leucine rich repeat NTF2 PF02136.15 EMC95373.1 - 0.011 16.0 0.1 0.036 14.4 0.0 1.9 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain LRR_6 PF13516.1 EMC95373.1 - 0.012 15.5 1.9 0.65 10.2 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 EMC95373.1 - 0.013 15.5 1.5 0.5 10.7 0.2 3.7 4 0 0 4 4 4 0 Leucine rich repeat LRR_9 PF14580.1 EMC95373.1 - 0.022 14.3 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Ribosomal_S5_C PF03719.10 EMC95373.1 - 0.047 12.9 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain SF3b1 PF08920.5 EMC95374.1 - 5.4e-30 104.3 6.6 7.8e-29 100.5 4.5 2.9 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EMC95374.1 - 4.2e-15 55.7 0.3 0.01 16.1 0.0 7.2 5 3 3 9 9 9 4 HEAT repeats HEAT PF02985.17 EMC95374.1 - 4.4e-11 41.8 7.5 0.17 12.0 0.1 9.4 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EMC95374.1 - 4.3e-10 39.7 2.1 0.51 10.9 0.0 7.6 6 2 2 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.15 EMC95374.1 - 3.1e-05 22.4 0.3 0.012 13.9 0.0 3.3 3 1 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EMC95374.1 - 4.4e-05 23.7 0.1 2.2 8.7 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EMC95374.1 - 0.0044 16.4 0.1 0.98 8.7 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.7 EMC95374.1 - 0.0045 16.3 0.4 14 4.9 0.0 4.4 4 0 0 4 4 4 1 NUC173 domain Acetyltransf_1 PF00583.19 EMC95375.1 - 3.4e-13 49.4 0.2 4.9e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMC95375.1 - 3.5e-06 27.1 0.1 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC95375.1 - 2.3e-05 24.4 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC95375.1 - 2.6e-05 23.8 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EMC95375.1 - 0.00037 20.4 0.0 0.00047 20.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC95375.1 - 0.0029 17.4 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EMC95375.1 - 0.0039 17.1 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMC95375.1 - 0.013 15.6 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 EMC95376.1 - 7.7e-120 400.5 29.0 8.8e-120 400.3 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC95376.1 - 1.7e-24 86.2 64.9 8.6e-22 77.3 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C4H2 PF10146.4 EMC95377.1 - 0.42 10.5 20.5 0.69 9.8 14.2 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Peptidase_M20 PF01546.23 EMC95379.1 - 2.9e-28 98.6 0.1 4.4e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMC95379.1 - 1.7e-11 43.8 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMC95379.1 - 0.0026 17.5 0.0 0.0056 16.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 PWI PF01480.12 EMC95383.1 - 8.8e-23 80.2 0.0 1.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 PWI domain Flocculin PF00624.13 EMC95383.1 - 0.13 12.0 0.3 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Flocculin repeat Pro_isomerase PF00160.16 EMC95384.1 - 7.1e-52 175.7 0.0 1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_11 PF08241.7 EMC95385.1 - 1.1e-16 61.0 0.1 2.7e-16 59.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC95385.1 - 1.2e-16 60.6 0.0 1.7e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC95385.1 - 1.2e-14 54.5 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC95385.1 - 6.7e-14 51.6 0.0 1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMC95385.1 - 7.7e-14 52.2 0.0 1.2e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC95385.1 - 3.4e-09 36.9 0.1 5.8e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC95385.1 - 5.2e-09 36.0 0.0 6.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC95385.1 - 1.1e-07 31.8 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMC95385.1 - 3.1e-07 29.7 0.0 4.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EMC95385.1 - 3.3e-07 30.0 0.0 7.8e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EMC95385.1 - 3.6e-06 26.2 0.0 4.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EMC95385.1 - 5.1e-06 25.7 0.0 8.3e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EMC95385.1 - 1.2e-05 25.0 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC95385.1 - 1.4e-05 24.2 0.0 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 EMC95385.1 - 1.4e-05 23.9 0.0 2.9e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 EMC95385.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.7 EMC95385.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EMC95385.1 - 0.0019 17.3 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.8 EMC95385.1 - 0.0027 17.0 0.8 0.0032 16.7 0.0 1.4 2 0 0 2 2 1 1 Histone methylation protein DOT1 Methyltransf_5 PF01795.14 EMC95385.1 - 0.013 14.7 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 MraW methylase family UPF0020 PF01170.13 EMC95385.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DREV PF05219.7 EMC95385.1 - 0.15 10.8 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase FmrO PF07091.6 EMC95385.1 - 0.15 11.0 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) cobW PF02492.14 EMC95386.1 - 2.9e-32 111.5 0.0 3.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EMC95386.1 - 2.1e-06 26.7 0.8 2.1e-05 23.4 0.6 1.9 1 1 0 1 1 1 1 ArgK protein AAA_23 PF13476.1 EMC95386.1 - 0.0054 17.0 0.0 0.0059 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMC95386.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase TMEM51 PF15345.1 EMC95386.1 - 0.055 13.1 0.0 0.075 12.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_25 PF13481.1 EMC95386.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EMC95386.1 - 0.086 12.2 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EMC95386.1 - 0.096 13.5 0.1 0.17 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EMC95386.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein SNF2_N PF00176.18 EMC95387.1 - 6.6e-38 130.2 0.0 1.7e-34 119.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 EMC95387.1 - 0.0077 16.0 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AMP_N PF05195.11 EMC95387.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Helicase_C PF00271.26 EMC95387.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain GAS2 PF02187.12 EMC95388.1 - 8.2e-05 22.2 0.1 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Ebola_NP PF05505.7 EMC95389.1 - 0.18 9.8 4.1 0.19 9.7 2.9 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Med15 PF09606.5 EMC95389.1 - 0.73 7.9 10.5 0.86 7.7 7.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1509 PF07420.6 EMC95389.1 - 1.5 8.0 7.1 2.1 7.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF3043 PF11241.3 EMC95389.1 - 3.5 7.1 8.9 4.7 6.7 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2470 PF10615.4 EMC95393.1 - 4.4e-23 81.2 0.3 6.8e-23 80.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) HMG_box PF00505.14 EMC95394.1 - 1.3e-20 73.4 0.4 2.4e-20 72.5 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC95394.1 - 7e-05 23.1 0.1 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF3667 PF12412.3 EMC95395.1 - 0.025 13.8 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) 6PF2K PF01591.13 EMC95396.1 - 1.2e-79 266.4 0.1 1.6e-79 266.0 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMC95396.1 - 6.5e-31 107.5 0.0 2e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMC95396.1 - 1.2e-07 31.7 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMC95396.1 - 0.0028 16.8 0.0 0.0058 15.8 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EMC95396.1 - 0.019 15.7 0.1 0.098 13.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF4248 PF14053.1 EMC95396.1 - 0.11 12.0 0.1 2.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) 2-Hacid_dh_C PF02826.14 EMC95397.1 - 1.6e-42 144.6 0.4 9.6e-28 96.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC95397.1 - 0.017 14.5 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 EMC95397.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Dehalogenase PF13486.1 EMC95397.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Reductive dehalogenase subunit DUF1512 PF07431.7 EMC95397.1 - 0.15 10.8 0.1 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) NMT1 PF09084.6 EMC95397.1 - 0.16 11.5 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Dus PF01207.12 EMC95398.1 - 1e-47 162.5 0.1 3.4e-47 160.7 0.1 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) IFRD_C PF04836.7 EMC95398.1 - 0.021 15.0 0.3 0.047 13.8 0.2 1.6 1 0 0 1 1 1 0 Interferon-related protein conserved region zf-HC5HC2H_2 PF13832.1 EMC95400.1 - 7.5e-19 67.7 1.6 7.5e-19 67.7 1.1 3.7 3 1 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC95400.1 - 8.6e-16 57.8 2.9 8.6e-16 57.8 2.0 4.5 5 0 0 5 5 5 2 PHD-like zinc-binding domain BAH PF01426.13 EMC95400.1 - 1.4e-14 53.8 0.1 3.4e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EMC95400.1 - 7.8e-12 44.7 52.2 1.3e-06 28.0 6.6 6.0 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 EMC95400.1 - 6.1e-05 22.2 4.7 6.1e-05 22.2 3.2 5.5 6 0 0 6 6 6 3 PHD-finger Prok-RING_1 PF14446.1 EMC95400.1 - 0.25 11.1 35.7 0.51 10.1 2.5 5.1 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 RecR PF02132.10 EMC95400.1 - 2 7.9 15.5 1.7 8.1 2.1 3.9 3 0 0 3 3 3 0 RecR protein IQ PF00612.22 EMC95401.1 - 0.00029 20.1 1.0 0.00029 20.1 0.7 1.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF2580 PF10824.3 EMC95401.1 - 0.037 14.3 0.5 0.053 13.8 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2580) DUF3659 PF12396.3 EMC95402.1 - 2.8e-286 923.7 169.2 1.7e-23 82.0 2.1 15.4 16 1 0 16 16 16 14 Protein of unknown function (DUF3659) F-box-like PF12937.2 EMC95403.1 - 0.002 17.8 0.0 0.014 15.1 0.0 2.5 1 1 0 1 1 1 1 F-box-like Glyco_transf_90 PF05686.7 EMC95404.1 - 3.5e-12 45.7 0.3 9.4e-09 34.4 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 tRNA-synt_2d PF01409.15 EMC95405.1 - 1.6e-42 145.4 0.1 1.2e-22 80.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EMC95405.1 - 1.7e-23 82.6 0.0 4.5e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EMC95406.1 - 3.5e-58 193.3 0.2 3.7e-20 71.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Laminin_N PF00055.12 EMC95407.1 - 0.0037 16.2 0.0 0.004 16.1 0.0 1.0 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) NAGLU PF05089.7 EMC95408.1 - 4.1e-126 420.2 9.9 6.7e-126 419.5 6.9 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EMC95408.1 - 1.1e-58 198.7 3.4 1.6e-58 198.1 2.3 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EMC95408.1 - 3.4e-20 71.4 0.1 1.7e-19 69.2 0.0 2.2 2 1 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Abhydrolase_3 PF07859.8 EMC95409.1 - 1.9e-31 109.2 0.0 1.6e-22 80.0 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold PAT1 PF09770.4 EMC95410.1 - 7.5 4.6 17.8 7.7 4.6 12.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 EMC95411.1 - 1.3e-38 132.6 29.5 1.9e-38 132.0 20.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_38 PF01074.17 EMC95413.1 - 6.5e-87 291.2 0.7 1.3e-86 290.3 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EMC95413.1 - 1.7e-70 238.1 0.0 2.6e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EMC95413.1 - 4.4e-25 87.7 0.0 9.5e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Peptidase_S9 PF00326.16 EMC95414.1 - 1.1e-47 162.0 0.0 3.4e-47 160.4 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMC95414.1 - 4.9e-11 42.9 0.7 1.6e-10 41.2 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC95414.1 - 2.4e-08 33.8 0.0 5.2e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMC95414.1 - 0.0031 16.9 0.7 0.0056 16.1 0.5 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EMC95414.1 - 0.12 11.9 0.0 1.7 8.1 0.0 2.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Phage_holin_5 PF06946.6 EMC95416.1 - 8 6.6 6.9 6.6 6.9 1.2 2.9 2 1 1 3 3 3 0 Phage holin Dynactin PF12455.3 EMC95417.1 - 5.6e-70 235.3 3.3 5.6e-70 235.3 2.3 3.3 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EMC95417.1 - 8.2e-21 73.4 0.1 1.5e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LIP PF03583.9 EMC95418.1 - 7.1e-61 205.9 0.1 1e-60 205.4 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EMC95418.1 - 6.3e-07 29.2 0.0 1.9e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC95418.1 - 0.0001 22.2 2.5 0.001 19.0 1.7 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMC95418.1 - 0.024 13.9 0.0 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EMC95418.1 - 0.11 11.7 0.4 3.5 6.7 0.0 2.7 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMC95418.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase NUC173 PF08161.7 EMC95419.1 - 3.6e-74 248.4 0.1 8.2e-72 240.7 0.0 2.8 2 0 0 2 2 2 2 NUC173 domain HEAT PF02985.17 EMC95419.1 - 0.076 13.1 0.2 18 5.7 0.0 3.5 2 0 0 2 2 2 0 HEAT repeat SLT PF01464.15 EMC95420.1 - 0.015 14.7 0.0 0.033 13.7 0.0 1.5 2 0 0 2 2 2 0 Transglycosylase SLT domain DUF1749 PF08538.5 EMC95420.1 - 0.15 10.9 0.0 0.82 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF2183 PF09949.4 EMC95422.1 - 4.4e-33 113.1 0.0 2.2e-32 110.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EMC95422.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF2611 PF11022.3 EMC95422.1 - 0.18 11.8 0.0 0.54 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) Cu-oxidase_2 PF07731.9 EMC95423.1 - 1.2e-37 128.5 2.4 4.5e-35 120.1 0.2 3.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMC95423.1 - 5.8e-28 97.0 5.8 8.9e-19 67.3 0.4 3.6 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EMC95423.1 - 4.1e-24 85.2 0.6 1.3e-23 83.6 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase HET PF06985.6 EMC95424.1 - 8.4e-33 113.4 0.0 9.7e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNA_pol_A_bac PF01000.21 EMC95425.1 - 2.1e-24 85.8 0.0 2.1e-23 82.6 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMC95425.1 - 9.1e-14 50.3 0.0 1.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 EMC95426.1 - 1.2e-132 440.9 0.0 1.6e-132 440.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EMC95426.1 - 0.21 10.2 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase MTBP_C PF14920.1 EMC95427.1 - 0.008 15.6 0.1 0.01 15.3 0.1 1.1 1 0 0 1 1 1 1 MDM2-binding VanW PF04294.8 EMC95427.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 VanW like protein NmrA PF05368.8 EMC95429.1 - 5.3e-21 74.9 0.0 1.2e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC95429.1 - 5.4e-05 23.2 0.0 0.00015 21.8 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EMC95429.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Dynamitin PF04912.9 EMC95430.1 - 5.4e-18 64.9 6.4 1.2e-16 60.5 1.4 2.4 3 0 0 3 3 3 2 Dynamitin DivIC PF04977.10 EMC95430.1 - 0.0034 16.8 4.0 0.021 14.3 0.2 2.7 2 0 0 2 2 2 1 Septum formation initiator TPR_MLP1_2 PF07926.7 EMC95430.1 - 0.098 12.4 8.8 0.26 11.0 1.4 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EMC95430.1 - 3.2 7.5 11.2 0.31 10.8 3.8 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.15 EMC95430.1 - 3.4 7.4 9.1 1.6 8.5 0.7 2.8 2 0 0 2 2 2 0 Prefoldin subunit Remorin_C PF03763.8 EMC95430.1 - 4 6.9 10.7 1 8.9 1.1 3.1 3 0 0 3 3 3 0 Remorin, C-terminal region SRF-TF PF00319.13 EMC95431.1 - 1.7e-21 75.1 0.0 2.5e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) tRNA-synt_1 PF00133.17 EMC95433.1 - 1.1e-211 704.0 0.0 1.6e-210 700.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMC95433.1 - 5.6e-36 123.6 0.0 1.3e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMC95433.1 - 2e-17 62.9 0.3 2.4e-07 29.7 0.0 5.0 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EMC95433.1 - 2.2e-10 40.1 0.0 7.3e-07 28.6 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EMC95433.1 - 0.0018 17.4 0.0 0.058 12.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EMC95433.1 - 0.0035 16.2 0.0 0.15 10.8 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) DUF3408 PF11888.3 EMC95433.1 - 0.4 10.6 3.3 9.9 6.0 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Pkinase PF00069.20 EMC95435.1 - 2.2e-59 200.7 0.3 2.6e-59 200.5 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC95435.1 - 3e-19 69.1 0.0 4.3e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC95435.1 - 8e-07 29.0 0.0 1.7e-05 24.7 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC95435.1 - 0.0049 16.4 0.2 0.017 14.6 0.1 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EMC95435.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Transgly PF00912.17 EMC95435.1 - 0.045 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase Kdo PF06293.9 EMC95435.1 - 0.052 12.6 0.1 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-DHHC PF01529.15 EMC95436.1 - 6.3e-34 116.8 5.4 9.1e-34 116.3 3.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase 3-HAO PF06052.7 EMC95437.1 - 1.2e-55 187.0 0.0 1.5e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase DZR PF12773.2 EMC95437.1 - 9e-05 22.2 2.5 0.00014 21.5 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon Cupin_2 PF07883.6 EMC95437.1 - 0.00062 19.2 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain FYVE PF01363.16 EMC95437.1 - 0.01 15.7 1.8 0.018 14.9 1.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger AraC_binding PF02311.14 EMC95437.1 - 0.01 15.5 0.1 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain TF_Zn_Ribbon PF08271.7 EMC95437.1 - 0.018 14.3 1.2 1.3 8.3 0.1 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Nudix_N_2 PF14803.1 EMC95437.1 - 0.021 14.5 1.1 0.79 9.4 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal ADK_lid PF05191.9 EMC95437.1 - 0.24 11.0 3.3 0.8 9.4 0.8 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.1 EMC95437.1 - 0.27 10.5 5.3 4.5 6.6 3.6 2.2 1 1 1 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EMC95437.1 - 0.64 9.7 4.1 2.8 7.6 0.2 2.3 1 1 2 3 3 3 0 Putative transposase DNA-binding domain RNA_POL_M_15KD PF02150.11 EMC95437.1 - 3.3 7.4 7.1 5.9 6.6 0.1 3.0 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit HEAT_2 PF13646.1 EMC95438.1 - 0.12 12.6 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 HEAT repeats DUF3361 PF11841.3 EMC95438.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Nop14 PF04147.7 EMC95439.1 - 1.8e-215 717.5 26.1 3.6e-166 554.5 10.4 2.1 1 1 1 2 2 2 2 Nop14-like family Med15 PF09606.5 EMC95440.1 - 1.9 6.5 24.1 2.6 6.1 16.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Metallophos PF00149.23 EMC95441.1 - 2.4e-10 40.1 0.7 1.3e-09 37.7 0.5 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3612 PF12268.3 EMC95443.1 - 0.088 12.5 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Pkinase PF00069.20 EMC95445.1 - 8.4e-40 136.5 0.0 3e-22 79.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC95445.1 - 1.1e-17 64.0 0.0 3.4e-17 62.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC95445.1 - 2.3e-07 30.7 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC95445.1 - 0.07 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ribosomal_L10 PF00466.15 EMC95446.1 - 1.1e-24 86.2 0.1 2.3e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EMC95446.1 - 5e-19 68.4 7.5 5e-19 68.4 5.2 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 EMC95446.1 - 0.033 13.7 2.7 0.054 13.0 1.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region S19 PF06756.6 EMC95446.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S19 C-terminal FR47 PF08445.5 EMC95447.1 - 6.6e-06 25.8 0.0 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EMC95447.1 - 0.0031 17.5 0.0 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMC95447.1 - 0.02 15.0 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DJ-1_PfpI PF01965.19 EMC95448.1 - 1.1e-23 83.3 0.1 1.4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EMC95448.1 - 9.7e-18 63.4 0.1 2.2e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family ThiF PF00899.16 EMC95449.1 - 3.4e-40 137.0 0.6 2.1e-39 134.4 0.0 2.2 2 1 1 3 3 3 1 ThiF family UBACT PF02134.16 EMC95449.1 - 2.1e-25 88.0 1.4 4.3e-25 87.0 1.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EMC95449.1 - 1.3e-23 82.4 0.0 2.2e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EMC95449.1 - 8e-15 53.9 2.7 8e-15 53.9 1.9 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EMC95449.1 - 0.00024 21.2 0.0 0.00065 19.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMC95449.1 - 0.1 12.5 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Telomere_reg-2 PF10193.4 EMC95450.1 - 4.9e-30 104.1 0.0 1.3e-29 102.7 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein IpaB_EvcA PF03278.8 EMC95450.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 IpaB/EvcA family Colicin-DNase PF12639.2 EMC95451.1 - 0.13 12.4 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Hexokinase_2 PF03727.11 EMC95452.1 - 3e-76 255.8 0.0 3.7e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EMC95452.1 - 1.2e-52 178.2 0.0 1.5e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase SNAP PF14938.1 EMC95454.1 - 1.5e-115 385.2 16.2 1.7e-115 385.0 11.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EMC95454.1 - 0.0016 18.3 17.4 0.064 13.2 2.1 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC95454.1 - 0.0019 17.8 15.1 0.79 9.6 0.1 6.2 3 1 3 6 6 6 1 Tetratricopeptide repeat PhageMin_Tail PF10145.4 EMC95454.1 - 0.026 14.1 2.6 0.16 11.6 1.8 2.2 1 1 0 1 1 1 0 Phage-related minor tail protein Spatacsin_C PF14649.1 EMC95454.1 - 0.11 11.3 8.5 3.8 6.2 0.2 3.3 1 1 2 3 3 3 0 Spatacsin C-terminus DUF2521 PF10730.4 EMC95454.1 - 0.13 12.0 1.5 0.22 11.3 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2521) TPR_11 PF13414.1 EMC95454.1 - 0.17 11.5 20.3 0.35 10.5 3.0 3.8 2 1 1 3 3 3 0 TPR repeat UVR PF02151.14 EMC95454.1 - 0.72 9.4 8.6 5.5 6.6 0.0 4.4 4 0 0 4 4 4 0 UvrB/uvrC motif TPR_2 PF07719.12 EMC95454.1 - 1 9.4 22.3 1.6 8.8 0.1 6.6 4 1 4 8 8 8 0 Tetratricopeptide repeat MIT PF04212.13 EMC95454.1 - 4.5 7.2 13.7 1.9 8.4 0.4 4.2 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Mus7 PF09462.5 EMC95455.1 - 3.2e-132 442.4 0.0 5e-132 441.8 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family Tetraspannin PF00335.15 EMC95456.1 - 1.8e-05 24.1 0.4 3.5e-05 23.2 0.3 1.6 1 1 0 1 1 1 1 Tetraspanin family BCDHK_Adom3 PF10436.4 EMC95457.1 - 7.5e-69 230.4 0.0 1e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMC95457.1 - 1.4e-16 60.2 0.0 2.7e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMC95457.1 - 0.0053 16.4 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gly-zipper_Omp PF13488.1 EMC95458.1 - 5.8 6.6 33.1 0.11 12.1 12.5 2.5 1 1 1 2 2 2 0 Glycine zipper Sugar_tr PF00083.19 EMC95461.1 - 4.1e-77 259.6 31.9 4.8e-77 259.4 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC95461.1 - 3.5e-26 91.7 51.0 2.7e-25 88.8 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glu-tRNAGln PF02686.10 EMC95463.1 - 0.00014 21.5 0.1 0.00077 19.2 0.0 2.0 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit MFS_1 PF07690.11 EMC95464.1 - 1.7e-54 184.8 24.3 1.7e-54 184.8 16.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC95464.1 - 7.9e-17 60.9 11.5 7.9e-17 60.9 8.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 EMC95464.1 - 0.056 13.2 0.1 0.056 13.2 0.1 3.5 3 1 1 4 4 4 0 MFS_1 like family Zn-ribbon_8 PF09723.5 EMC95465.1 - 0.0021 17.9 2.7 0.0058 16.5 1.9 1.8 1 1 0 1 1 1 1 Zinc ribbon domain zf-ribbon_3 PF13248.1 EMC95465.1 - 0.014 14.6 2.5 0.023 13.8 1.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain SprT-like PF10263.4 EMC95465.1 - 0.025 14.2 0.3 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 SprT-like family zf-CSL PF05207.8 EMC95465.1 - 0.034 13.6 0.1 0.069 12.6 0.1 1.4 1 0 0 1 1 1 0 CSL zinc finger HypA PF01155.14 EMC95465.1 - 0.035 13.7 0.0 0.04 13.6 0.0 1.3 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_5 PF13719.1 EMC95465.1 - 0.048 13.2 0.2 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain HHH_8 PF14716.1 EMC95465.1 - 0.05 13.7 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain ProQ PF04352.8 EMC95465.1 - 0.057 13.0 0.1 0.17 11.4 0.0 1.7 1 1 1 2 2 2 0 ProQ/FINO family zinc_ribbon_4 PF13717.1 EMC95465.1 - 0.086 12.5 0.3 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 EMC95465.1 - 0.16 12.3 4.1 0.41 11.0 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EMC95465.1 - 0.3 10.6 2.7 6.4 6.4 2.1 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.1 EMC95465.1 - 2.2 8.3 4.7 0.35 10.8 0.5 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC95465.1 - 3.5 8.1 6.2 0.51 10.7 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type NUDIX PF00293.23 EMC95467.1 - 1.9e-11 43.7 0.0 3.4e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain DUF605 PF04652.11 EMC95467.1 - 0.54 9.6 9.9 0.68 9.2 6.9 1.2 1 0 0 1 1 1 0 Vta1 like LETM1 PF07766.8 EMC95468.1 - 2.4e-105 351.4 0.3 5e-105 350.3 0.2 1.5 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EMC95468.1 - 7.8e-08 31.6 0.0 0.00046 19.6 0.0 3.6 3 0 0 3 3 3 2 SAP domain DUF3614 PF12267.3 EMC95468.1 - 3.1 8.0 5.1 1.2 9.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) ADK PF00406.17 EMC95469.1 - 9.1e-34 116.5 0.0 1.7e-19 70.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EMC95469.1 - 6.7e-15 54.4 0.0 1.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EMC95469.1 - 0.0092 16.7 0.0 0.035 14.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC95469.1 - 0.013 15.8 0.0 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMC95469.1 - 0.09 12.6 0.0 0.41 10.5 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.9 EMC95469.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BTB PF00651.26 EMC95470.1 - 2.9e-08 33.6 0.0 5.5e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain zinc_ribbon_5 PF13719.1 EMC95470.1 - 0.016 14.7 0.3 4.3 6.9 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EMC95470.1 - 0.036 13.2 1.5 0.097 11.9 1.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EMC95470.1 - 0.043 14.1 0.2 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_L37ae PF01780.14 EMC95470.1 - 0.1 12.5 1.1 0.22 11.3 0.7 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family TF_Zn_Ribbon PF08271.7 EMC95470.1 - 0.13 11.6 1.1 0.2 11.0 0.1 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 EMC95470.1 - 0.13 11.9 3.0 5.3 6.8 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 EMC95470.1 - 0.14 12.5 4.0 0.19 12.0 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-CGNR PF11706.3 EMC95470.1 - 0.63 9.5 3.6 1.5 8.3 2.5 1.6 1 0 0 1 1 1 0 CGNR zinc finger zf-HIT PF04438.11 EMC95470.1 - 1.3 8.7 6.1 0.33 10.6 1.1 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-H2C2_2 PF13465.1 EMC95471.1 - 0.056 13.7 0.8 0.17 12.2 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger double domain DUF2521 PF10730.4 EMC95471.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) Bromodomain PF00439.20 EMC95472.1 - 1.1e-32 111.7 0.4 1e-17 63.7 0.3 2.6 2 0 0 2 2 2 2 Bromodomain Arm_2 PF04826.8 EMC95472.1 - 0.17 10.9 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Armadillo-like zf-RING_2 PF13639.1 EMC95474.1 - 1.2e-13 50.5 5.9 1.9e-13 50.0 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC95474.1 - 6.9e-09 35.2 2.8 1.1e-08 34.6 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC95474.1 - 3.4e-08 33.4 1.0 6.8e-08 32.5 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC95474.1 - 1.5e-06 27.7 3.1 2.4e-06 27.1 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC95474.1 - 2.3e-06 27.5 4.5 3.5e-06 26.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC95474.1 - 4.9e-05 22.9 1.9 7.4e-05 22.3 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC95474.1 - 0.002 17.8 2.5 0.0057 16.4 1.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EMC95474.1 - 0.025 14.2 5.2 0.042 13.5 3.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EMC95474.1 - 0.034 13.7 6.0 0.054 13.0 4.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMC95474.1 - 0.15 11.9 4.1 0.29 11.0 2.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EMC95474.1 - 0.41 10.7 5.0 0.7 9.9 3.4 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EMC95474.1 - 0.94 9.2 8.0 0.072 12.8 0.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EMC95474.1 - 0.94 9.4 3.4 2.5 8.1 2.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain NTR2 PF15458.1 EMC95475.1 - 1.7e-54 184.7 19.3 2.7e-54 184.1 13.4 1.3 1 0 0 1 1 1 1 Nineteen complex-related protein 2 CPSase_L_D2 PF02786.12 EMC95476.1 - 5.6e-106 352.5 0.0 2.7e-81 271.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EMC95476.1 - 4e-42 142.8 0.0 1.1e-41 141.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EMC95476.1 - 5.3e-37 127.3 0.3 4.4e-20 72.1 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 EMC95476.1 - 1e-32 112.5 0.0 6.9e-16 58.3 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EMC95476.1 - 2.6e-24 85.5 0.0 9.1e-09 34.4 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMC95476.1 - 7.6e-18 64.4 0.0 2.3e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMC95476.1 - 5e-14 52.1 0.1 1.8e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EMC95476.1 - 1.6e-09 37.4 0.0 1.1e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EMC95476.1 - 6.4e-06 25.8 0.0 0.068 12.7 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EMC95476.1 - 2.1e-05 24.4 0.0 0.089 12.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 EMC95476.1 - 0.0007 18.8 0.0 0.087 12.0 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.16 EMC95476.1 - 0.014 14.8 1.0 0.3 10.4 0.0 3.0 4 0 0 4 4 4 0 NAD dependent epimerase/dehydratase family MCPsignal PF00015.16 EMC95476.1 - 0.075 12.5 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CDP-OH_P_transf PF01066.16 EMC95477.1 - 7e-14 51.9 17.6 4.2e-13 49.4 12.2 2.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Sugar_tr PF00083.19 EMC95479.1 - 2.2e-114 382.5 26.7 3e-113 378.7 18.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC95479.1 - 1.3e-14 53.6 42.2 2.6e-13 49.4 20.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily HSP70 PF00012.15 EMC95480.1 - 1.6e-231 769.4 10.5 1.8e-231 769.2 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC95480.1 - 1.6e-16 59.8 0.2 2.6e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EMC95480.1 - 6.4e-05 22.6 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EMC95480.1 - 0.017 13.9 0.9 0.19 10.5 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain p450 PF00067.17 EMC95481.1 - 1.8e-58 198.1 0.0 3.5e-58 197.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF4296 PF14129.1 EMC95481.1 - 0.066 13.3 0.2 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) CBFD_NFYB_HMF PF00808.18 EMC95482.1 - 2.3e-29 101.2 0.9 3.2e-29 100.7 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC95482.1 - 8.8e-07 28.9 0.1 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EMC95482.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EMC95482.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EMC95482.1 - 0.039 14.2 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.15 EMC95485.1 - 7.7e-24 83.4 4.9 9.1e-24 83.2 3.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit EzrA PF06160.7 EMC95485.1 - 0.036 12.2 3.9 0.81 7.7 0.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Prefoldin PF02996.12 EMC95485.1 - 0.036 13.7 3.3 0.64 9.6 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit p25-alpha PF05517.7 EMC95485.1 - 0.053 13.7 0.6 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 p25-alpha DASH_Dad3 PF08656.5 EMC95485.1 - 0.14 11.8 3.2 0.37 10.5 0.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Spc24 PF08286.6 EMC95485.1 - 0.24 11.0 5.6 1.8 8.2 0.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2205 PF10224.4 EMC95485.1 - 0.77 9.3 7.5 0.43 10.1 0.6 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) TPR_MLP1_2 PF07926.7 EMC95485.1 - 1.1 8.9 8.4 0.74 9.5 0.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EMC95485.1 - 4.9 6.7 7.5 30 4.1 5.2 1.9 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EMC95485.1 - 6.4 6.5 7.1 4.8 6.9 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Cmc1 PF08583.5 EMC95486.1 - 6.4e-20 70.7 5.1 7.3e-20 70.5 3.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like ProSAAS PF07259.7 EMC95486.1 - 0.046 13.2 0.3 0.051 13.1 0.2 1.1 1 0 0 1 1 1 0 ProSAAS precursor NDUF_B7 PF05676.8 EMC95486.1 - 0.062 12.7 1.3 0.084 12.3 0.9 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) TOM20_plant PF06552.7 EMC95488.1 - 0.0089 15.6 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_1 PF00515.23 EMC95488.1 - 3.4 7.4 5.5 2 8.1 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.5 EMC95490.1 - 5.7e-23 81.3 3.8 1.3e-22 80.2 1.4 2.4 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like Pex26 PF07163.7 EMC95490.1 - 4.8e-07 28.9 0.5 9.9e-07 27.9 0.3 1.5 1 1 0 1 1 1 1 Pex26 protein TPR_11 PF13414.1 EMC95490.1 - 0.0015 18.1 5.3 0.46 10.1 0.0 3.9 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EMC95490.1 - 0.0069 16.2 2.2 0.24 11.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC95490.1 - 0.009 15.9 10.0 0.19 11.6 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC95490.1 - 0.06 12.9 0.6 0.45 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC95490.1 - 0.096 13.1 3.8 20 5.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMC95490.1 - 1 10.1 12.5 3.1 8.5 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-GRF PF06839.7 EMC95493.1 - 0.0059 16.5 15.3 0.0074 16.1 3.8 2.7 2 1 0 2 2 2 2 GRF zinc finger Zn_ribbon_recom PF13408.1 EMC95493.1 - 2.2 8.5 11.6 1.3 9.3 6.0 1.9 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Peptidase_S15 PF02129.13 EMC95494.1 - 7.5e-39 133.7 0.9 1.1e-38 133.1 0.6 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMC95494.1 - 7.7e-39 133.8 0.1 1e-38 133.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMC95494.1 - 4.9e-07 29.8 0.1 1.4e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC95494.1 - 0.00019 21.2 0.0 0.0007 19.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family IN_DBD_C PF00552.16 EMC95494.1 - 0.0054 16.1 0.4 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Integrase DNA binding domain Hydrolase_4 PF12146.3 EMC95494.1 - 0.01 15.6 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Fungal_trans PF04082.13 EMC95497.1 - 8.9e-11 41.1 0.3 1.7e-10 40.2 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EMC95498.1 - 2.3e-13 49.6 5.9 5.3e-11 42.2 1.4 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC95498.1 - 3.2e-09 36.5 7.5 8.2e-07 29.0 1.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC95498.1 - 1.4e-05 25.1 9.5 0.00013 22.0 2.0 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC95498.1 - 0.00015 21.5 4.5 0.013 15.3 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC95498.1 - 0.003 17.1 5.6 0.0058 16.2 0.4 2.3 2 1 0 2 2 2 1 zinc-finger of a C2HC-type C1_4 PF07975.7 EMC95498.1 - 0.0034 17.3 3.7 0.14 12.1 2.9 2.0 1 1 1 2 2 2 2 TFIIH C1-like domain zf-met PF12874.2 EMC95498.1 - 0.0041 17.2 3.2 0.03 14.5 0.4 2.3 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC95498.1 - 0.0062 16.6 2.4 0.88 9.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 EMC95498.1 - 0.0086 15.8 3.1 1.2 8.9 0.3 2.1 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 EMC95498.1 - 0.01 15.8 1.3 0.13 12.2 0.2 2.1 2 0 0 2 2 2 1 zinc-finger Zn-ribbon_8 PF09723.5 EMC95498.1 - 0.011 15.6 4.6 0.26 11.2 3.2 2.1 1 1 0 1 1 1 0 Zinc ribbon domain gag_pre-integrs PF13976.1 EMC95498.1 - 0.016 14.8 1.2 0.097 12.3 0.0 1.9 1 1 1 2 2 2 0 GAG-pre-integrase domain RRN7 PF11781.3 EMC95498.1 - 0.03 13.8 1.6 4.3 6.9 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_4 PF13717.1 EMC95498.1 - 0.031 13.9 2.9 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 EMC95498.1 - 0.04 14.0 4.1 0.06 13.4 2.9 1.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF329 PF03884.9 EMC95498.1 - 0.052 13.1 0.6 2.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zinc_ribbon_5 PF13719.1 EMC95498.1 - 0.065 12.8 3.1 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain NADH-G_4Fe-4S_3 PF10588.4 EMC95498.1 - 0.12 11.6 2.8 0.57 9.4 0.1 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF2256 PF10013.4 EMC95498.1 - 0.13 12.0 2.6 5.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) TFIIS_C PF01096.13 EMC95498.1 - 0.16 11.6 2.0 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Arc_trans_TRASH PF08394.5 EMC95498.1 - 0.17 12.0 1.5 6.5 6.9 0.1 2.2 2 0 0 2 2 2 0 Archaeal TRASH domain zf-AN1 PF01428.11 EMC95498.1 - 0.18 11.6 6.4 2.7 7.9 0.4 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger zf-UBR PF02207.15 EMC95498.1 - 0.2 11.4 4.9 0.97 9.1 0.5 2.1 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Ribosomal_L37ae PF01780.14 EMC95498.1 - 0.23 11.3 1.7 5 7.0 0.1 2.0 1 1 0 2 2 2 0 Ribosomal L37ae protein family Elf1 PF05129.8 EMC95498.1 - 0.32 10.7 4.3 2.3 7.9 0.4 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.7 EMC95498.1 - 0.35 10.7 3.1 5.9 6.7 0.2 2.0 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_2 PF12756.2 EMC95498.1 - 0.39 10.8 2.8 2.5 8.2 2.0 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Mut7-C PF01927.11 EMC95498.1 - 0.42 10.5 3.1 5.2 7.0 0.2 1.9 1 1 1 2 2 2 0 Mut7-C RNAse domain PHD PF00628.24 EMC95498.1 - 0.48 10.1 3.3 3.2 7.5 2.3 1.9 1 1 0 1 1 1 0 PHD-finger zf-CHY PF05495.7 EMC95498.1 - 0.5 10.5 3.3 0.99 9.6 2.3 1.5 1 1 0 1 1 1 0 CHY zinc finger C1_1 PF00130.17 EMC95498.1 - 0.58 9.9 3.2 4.2 7.1 0.2 2.0 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EMC95498.1 - 0.6 9.9 3.8 2.5 7.9 2.6 1.8 1 1 0 1 1 1 0 Ring finger domain Evr1_Alr PF04777.8 EMC95498.1 - 0.79 9.6 3.8 2.3 8.1 0.2 2.0 1 1 1 2 2 2 0 Erv1 / Alr family DUF678 PF05077.7 EMC95498.1 - 0.89 9.5 3.3 5.4 7.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF678) zf-RING_5 PF14634.1 EMC95498.1 - 1.5 8.6 4.8 16 5.2 3.5 2.0 1 1 1 2 2 2 0 zinc-RING finger domain FYVE PF01363.16 EMC95498.1 - 2.1 8.2 6.2 20 5.1 4.3 2.0 1 1 0 1 1 1 0 FYVE zinc finger LigB PF02900.13 EMC95499.1 - 5.9e-19 68.1 0.0 6.9e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase p450 PF00067.17 EMC95500.1 - 9.9e-70 235.3 0.0 1.2e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 EMC95501.1 - 1.7e-08 33.8 0.1 4.5e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EMC95501.1 - 6.6e-05 22.3 0.0 9.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Cupin FAD_binding_3 PF01494.14 EMC95502.1 - 5.5e-19 68.4 0.1 8.7e-12 44.7 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EMC95502.1 - 1.2e-05 25.6 0.0 0.066 13.6 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMC95502.1 - 0.00072 18.3 0.1 0.36 9.4 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.19 EMC95502.1 - 0.0026 16.7 0.5 1.2 7.9 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC95502.1 - 0.0068 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMC95502.1 - 0.012 14.5 0.1 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMC95502.1 - 0.036 13.9 0.1 0.094 12.5 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAA_hydrolase PF01557.13 EMC95503.1 - 1.6e-40 138.9 0.0 2.1e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMC95503.1 - 9.4e-22 77.0 0.0 1.6e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Sirohm_synth_M PF14824.1 EMC95503.1 - 0.18 10.8 0.9 7.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central adh_short_C2 PF13561.1 EMC95504.1 - 6e-24 85.1 0.0 7.8e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC95504.1 - 1.1e-19 71.0 5.0 1.4e-19 70.5 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC95504.1 - 2.7e-07 30.4 2.4 3.9e-07 29.8 1.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC95504.1 - 0.00056 19.4 0.6 0.0019 17.6 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMC95504.1 - 0.0016 18.1 0.5 0.0035 17.1 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 EMC95505.1 - 6.6e-23 80.6 0.2 1.4e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC95505.1 - 6.1e-17 61.3 0.1 1.2e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ins_beta PF03488.9 EMC95505.1 - 0.041 13.6 1.1 0.076 12.8 0.8 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Methyltransf_18 PF12847.2 EMC95505.1 - 0.06 13.9 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EMC95506.1 - 4.4e-29 101.3 20.9 4.4e-29 101.3 14.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC95506.1 - 1.3e-15 56.9 2.4 1.3e-15 56.9 1.7 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMC95506.1 - 1.1e-06 27.1 2.2 2.1e-06 26.2 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FixP_N PF14715.1 EMC95506.1 - 0.01 15.1 0.0 0.068 12.5 0.0 2.5 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP EMP70 PF02990.11 EMC95506.1 - 1.8 6.9 10.1 0.059 11.8 2.1 1.8 2 0 0 2 2 2 0 Endomembrane protein 70 p450 PF00067.17 EMC95507.1 - 1e-56 192.4 0.0 1.3e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M1 PF01433.15 EMC95508.1 - 1.4e-09 37.5 0.0 0.021 13.9 0.0 3.2 2 1 1 3 3 3 3 Peptidase family M1 Aminotran_1_2 PF00155.16 EMC95510.1 - 1.1e-17 64.0 0.0 1.4e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EMC95510.1 - 0.00022 19.9 0.0 0.00064 18.3 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Lsm_interact PF05391.6 EMC95510.1 - 0.062 12.7 0.4 0.16 11.4 0.3 1.7 1 0 0 1 1 1 0 Lsm interaction motif DegT_DnrJ_EryC1 PF01041.12 EMC95510.1 - 0.087 11.8 0.2 0.9 8.5 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Mucin PF01456.12 EMC95512.1 - 6.3 6.5 20.9 0.78 9.5 9.0 2.7 3 0 0 3 3 3 0 Mucin-like glycoprotein SAS4 PF15460.1 EMC95513.1 - 3.1e-34 116.8 4.3 5.6e-34 116.0 3.0 1.4 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Pol_alpha_B_N PF08418.5 EMC95513.1 - 0.29 10.6 9.8 0.094 12.2 1.8 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF1136 PF06582.7 EMC95514.1 - 0.11 12.1 1.3 0.37 10.5 0.9 2.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) TetR_C_6 PF13977.1 EMC95514.1 - 0.12 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial transcriptional repressor Transferase PF02458.10 EMC95515.1 - 7.5e-21 74.0 0.0 9.4e-20 70.4 0.0 1.9 1 1 0 1 1 1 1 Transferase family DUF2844 PF11005.3 EMC95515.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) PCI PF01399.22 EMC95517.1 - 5.2e-22 78.1 0.3 1.3e-21 76.8 0.1 1.8 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 EMC95517.1 - 3.9e-19 68.8 0.2 8.7e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 EMC95517.1 - 0.0099 15.6 0.2 0.056 13.2 0.0 2.2 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EMC95517.1 - 0.17 11.9 0.7 1.4 9.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DASH_Spc34 PF08657.5 EMC95518.1 - 2.6e-46 158.4 1.4 6.9e-23 81.6 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 Spectrin PF00435.16 EMC95518.1 - 0.001 19.3 1.5 0.72 10.1 0.0 2.4 2 0 0 2 2 2 2 Spectrin repeat ISG65-75 PF11727.3 EMC95518.1 - 0.014 14.5 0.5 0.017 14.1 0.3 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein CENP-F_leu_zip PF10473.4 EMC95518.1 - 0.033 14.0 1.9 0.033 14.0 1.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_C31 PF05410.8 EMC95518.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha DUF4140 PF13600.1 EMC95518.1 - 0.65 10.4 9.0 2.7 8.4 0.3 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) BBS2_C PF14782.1 EMC95518.1 - 3.8 5.9 4.9 14 4.0 0.1 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Cu-oxidase PF00394.17 EMC95519.1 - 9e-27 93.9 0.1 1.7e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC95519.1 - 1.5e-09 37.4 2.2 2.4e-08 33.5 0.2 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMC95519.1 - 2.6e-08 33.5 0.3 4.8e-05 23.0 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase PfkB PF00294.19 EMC95520.1 - 8.5e-13 48.0 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase LRR_6 PF13516.1 EMC95521.1 - 9.2e-06 25.2 0.1 8 6.8 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeat F-box-like PF12937.2 EMC95521.1 - 0.0012 18.5 0.3 0.0029 17.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EMC95521.1 - 0.021 14.5 2.3 4.2 7.2 0.4 4.1 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EMC95521.1 - 0.075 12.6 1.8 10 5.8 0.0 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) GMC_oxred_N PF00732.14 EMC95522.1 - 9.3e-69 231.8 0.0 1.7e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC95522.1 - 1.3e-37 129.2 0.1 2.1e-37 128.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMC95522.1 - 1.4e-05 24.1 1.1 0.00017 20.6 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC95522.1 - 2.6e-05 23.2 2.2 0.0045 15.9 0.1 3.1 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC95522.1 - 3.6e-05 23.9 0.1 0.37 10.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC95522.1 - 0.00025 20.9 0.2 0.00074 19.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMC95522.1 - 0.00026 20.0 0.1 0.00042 19.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMC95522.1 - 0.00038 20.4 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC95522.1 - 0.001 18.2 0.1 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EMC95522.1 - 0.025 13.0 0.5 0.14 10.6 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EMC95522.1 - 0.15 11.7 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sugar_tr PF00083.19 EMC95523.1 - 5.7e-90 302.0 25.0 7.2e-90 301.7 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC95523.1 - 1.9e-15 56.4 36.1 2.3e-14 52.9 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_76 PF03663.9 EMC95524.1 - 2e-23 83.3 6.7 3.1e-16 59.7 1.1 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 Ctr PF04145.10 EMC95525.1 - 1e-30 106.6 1.5 1.2e-30 106.4 1.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF4134 PF13572.1 EMC95525.1 - 0.091 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Ferric_reduct PF01794.14 EMC95526.1 - 1.7e-17 63.6 16.6 1.7e-17 63.6 11.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMC95526.1 - 1.4e-15 57.5 0.0 4.8e-15 55.7 0.0 1.9 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMC95526.1 - 3.2e-13 49.4 0.0 6.8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 EMC95526.1 - 0.016 15.3 15.5 0.4 10.8 1.4 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Ribosomal_L27e PF01777.13 EMC95527.1 - 1.6e-35 121.0 1.4 2.3e-35 120.5 0.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EMC95527.1 - 0.011 15.4 0.2 0.033 13.9 0.1 1.9 1 0 0 1 1 1 0 KOW motif AMP-binding PF00501.23 EMC95529.1 - 3.9e-72 242.9 0.0 5.1e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GMC_oxred_N PF00732.14 EMC95529.1 - 4e-58 196.8 0.0 7.4e-58 196.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC95529.1 - 3.3e-31 108.4 0.0 7.2e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase AMP-binding_C PF13193.1 EMC95529.1 - 8.7e-15 55.4 0.0 4.3e-14 53.2 0.0 2.3 3 0 0 3 3 1 1 AMP-binding enzyme C-terminal domain FAD_binding_2 PF00890.19 EMC95529.1 - 5.4e-12 45.2 1.0 1.8e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMC95529.1 - 2.7e-08 33.1 0.0 8e-08 31.5 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMC95529.1 - 7e-05 21.9 0.1 0.00014 20.9 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMC95529.1 - 7.5e-05 22.6 0.7 0.00039 20.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMC95529.1 - 0.0041 16.2 0.1 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EMC95529.1 - 0.0043 16.1 0.2 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC95529.1 - 0.017 15.0 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC95529.1 - 0.023 14.7 0.0 0.99 9.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SinI PF08671.5 EMC95529.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.8 1 0 0 1 1 1 0 Anti-repressor SinI HI0933_like PF03486.9 EMC95529.1 - 0.12 10.8 0.1 0.28 9.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EMC95529.1 - 0.27 10.0 0.2 5.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A GDI PF00996.13 EMC95529.1 - 0.42 8.8 0.0 0.64 8.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Amidohydro_3 PF07969.6 EMC95531.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family DUF433 PF04255.9 EMC95532.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) ubiquitin PF00240.18 EMC95535.1 - 1.6e-34 117.0 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EMC95535.1 - 1.1e-27 95.5 3.1 2.3e-27 94.5 2.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EMC95535.1 - 5.8e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC95535.1 - 8.8e-06 25.8 0.2 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMC95535.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMC95535.1 - 0.0011 18.8 0.5 0.0024 17.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMC95535.1 - 0.0038 17.3 0.4 0.0053 16.9 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EMC95535.1 - 0.06 13.3 0.5 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) IBR PF01485.16 EMC95535.1 - 0.083 12.7 0.5 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 IBR domain Fer2_3 PF13085.1 EMC95535.1 - 0.12 12.1 1.1 0.23 11.2 0.7 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Plexin_cytopl PF08337.7 EMC95535.1 - 0.13 10.6 2.0 4.5 5.4 0.1 2.1 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain DNA_pol_E_B PF04042.11 EMC95536.1 - 2.4e-44 151.0 0.0 3.9e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B F-box-like_2 PF13013.1 EMC95537.1 - 0.003 17.2 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain GFO_IDH_MocA PF01408.17 EMC95539.1 - 4.4e-23 82.0 0.0 2.6e-22 79.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMC95539.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EMC95539.1 - 0.041 14.2 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TPR_11 PF13414.1 EMC95540.1 - 5.9e-14 51.4 7.0 6e-09 35.4 0.5 3.4 3 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EMC95540.1 - 8.9e-10 37.7 1.1 0.00036 19.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC95540.1 - 2.6e-09 36.3 2.4 0.066 13.1 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC95540.1 - 1.4e-05 25.6 1.6 0.00048 20.7 0.7 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC95540.1 - 0.00055 20.2 4.6 0.0006 20.0 0.4 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Pox_T4_N PF04491.7 EMC95540.1 - 0.00071 19.3 0.4 0.0081 15.9 0.0 2.5 2 0 0 2 2 2 1 Poxvirus T4 protein, N terminus TPR_12 PF13424.1 EMC95540.1 - 0.012 15.5 3.7 0.28 11.1 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC95540.1 - 0.013 15.3 4.9 1.1 9.2 0.0 3.7 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EMC95540.1 - 0.015 15.4 0.6 0.4 11.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC95540.1 - 0.044 13.9 4.5 0.13 12.4 1.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 EMC95540.1 - 0.052 12.1 0.0 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_14 PF13428.1 EMC95540.1 - 0.17 12.6 7.3 0.37 11.5 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Mcp5_PH PF12814.2 EMC95542.1 - 3.2e-41 140.0 0.0 8.1e-41 138.7 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3584 PF12128.3 EMC95542.1 - 0.061 10.6 13.7 0.083 10.2 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EMC95542.1 - 0.082 12.6 19.1 1.5 8.5 13.3 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EMC95542.1 - 2.3 7.1 15.0 3.8 6.4 10.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 EMC95542.1 - 4.1 6.9 11.1 0.72 9.3 4.4 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ank_2 PF12796.2 EMC95544.1 - 2.3e-31 107.9 0.7 2.5e-18 66.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC95544.1 - 3.8e-29 99.0 7.8 6e-07 28.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EMC95544.1 - 1.6e-25 88.9 0.7 6.5e-07 29.6 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC95544.1 - 1.5e-22 77.4 0.9 5.4e-05 23.0 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EMC95544.1 - 4.1e-19 68.1 3.1 9.5e-05 22.5 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) RVP PF00077.15 EMC95544.1 - 0.0046 16.8 2.1 35 4.4 0.0 3.9 2 2 2 4 4 4 0 Retroviral aspartyl protease DUF637 PF04830.8 EMC95544.1 - 0.011 15.4 5.9 0.079 12.6 0.2 2.7 1 1 2 3 3 3 0 Possible hemagglutinin (DUF637) PPR_3 PF13812.1 EMC95544.1 - 0.015 15.5 0.8 3.3 8.2 0.0 2.9 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DNA_processg_A PF02481.10 EMC95544.1 - 0.036 12.9 0.2 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 DNA recombination-mediator protein A Turandot PF07240.6 EMC95544.1 - 0.074 12.5 1.4 31 4.1 0.0 3.5 1 1 3 4 4 4 0 Stress-inducible humoral factor Turandot NACHT PF05729.7 EMC95545.1 - 1.5e-09 37.7 0.0 3.7e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMC95545.1 - 2.9e-06 27.3 0.0 9e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC95545.1 - 1.6e-05 25.0 0.0 9.8e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EMC95545.1 - 0.0034 16.4 0.7 0.79 8.6 0.1 2.3 1 1 0 2 2 2 2 KAP family P-loop domain AAA_14 PF13173.1 EMC95545.1 - 0.011 15.6 0.0 0.14 12.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EMC95545.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EMC95545.1 - 0.019 15.1 0.1 0.2 11.8 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EMC95545.1 - 0.02 15.1 0.0 0.084 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMC95545.1 - 0.04 13.3 0.3 0.1 12.0 0.2 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_30 PF13604.1 EMC95545.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC95545.1 - 0.057 13.5 0.0 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EMC95545.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EMC95545.1 - 0.068 13.9 0.9 0.56 11.0 0.6 2.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMC95545.1 - 0.078 12.8 0.1 0.28 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC95545.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HET PF06985.6 EMC95546.1 - 2.3e-24 86.1 3.7 1.7e-22 80.0 2.5 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3256 PF11644.3 EMC95546.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Oxidored_molyb PF00174.14 EMC95547.1 - 1.9e-43 147.8 0.0 3.1e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EMC95547.1 - 2.2e-37 127.6 0.9 4.5e-37 126.6 0.6 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 EMC95547.1 - 5.6e-19 68.7 0.2 2.7e-18 66.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMC95547.1 - 7.7e-18 64.4 0.0 2.1e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EMC95547.1 - 2.5e-14 52.8 0.1 5.4e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zn_clus PF00172.13 EMC95549.1 - 9.2e-09 35.0 8.6 1.6e-08 34.2 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC95549.1 - 2.3e-08 33.2 0.1 5.8e-08 31.9 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Redoxin PF08534.5 EMC95550.1 - 3.5e-29 101.2 0.0 4.2e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMC95550.1 - 1.2e-09 37.9 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 EMC95551.1 - 3.1e-36 123.6 0.0 6.1e-36 122.7 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EMC95551.1 - 9.6e-21 73.8 0.2 2.3e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Hexapep PF00132.19 EMC95552.1 - 2.6e-07 29.8 8.4 0.025 14.0 0.4 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 EMC95552.1 - 3.3e-07 30.1 3.0 3.3e-07 30.1 2.1 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.18 EMC95552.1 - 0.00047 19.5 0.0 0.00096 18.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EMC95552.1 - 0.0015 18.0 8.2 0.062 12.8 0.4 3.7 1 1 3 4 4 4 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EMC95552.1 - 0.0085 16.1 0.0 0.029 14.4 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain SEEK1 PF15357.1 EMC95553.1 - 0.0073 16.2 0.3 0.008 16.0 0.2 1.0 1 0 0 1 1 1 1 Psoriasis susceptibility 1 candidate 1 Methyltransf_11 PF08241.7 EMC95554.1 - 2.8e-08 34.1 0.0 5.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC95554.1 - 3.6e-07 30.7 0.0 6.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC95554.1 - 2.1e-05 24.8 0.0 3.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC95554.1 - 0.0007 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC95554.1 - 0.0073 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMC95554.1 - 0.025 13.5 0.0 0.092 11.7 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family RrnaAD PF00398.15 EMC95554.1 - 0.057 12.4 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pil1 PF13805.1 EMC95555.1 - 2.3e-92 308.9 4.1 2.8e-92 308.6 2.8 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 EMC95555.1 - 2.2 8.5 5.4 22 5.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DUF2247 PF10004.4 EMC95556.1 - 0.0097 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2247) WEMBL PF05701.6 EMC95556.1 - 0.01 14.3 10.4 0.017 13.5 7.2 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TSC22 PF01166.13 EMC95556.1 - 0.021 14.7 1.1 1.4 8.9 0.2 3.1 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4200 PF13863.1 EMC95556.1 - 0.028 14.3 1.6 0.028 14.3 1.1 3.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) YlzJ PF14035.1 EMC95556.1 - 0.032 14.2 0.1 0.27 11.3 0.0 2.4 2 0 0 2 2 2 0 YlzJ-like protein AphA_like PF14557.1 EMC95556.1 - 0.047 13.2 1.2 0.096 12.2 0.3 1.9 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator Filament PF00038.16 EMC95556.1 - 0.32 10.4 17.7 0.18 11.2 8.6 2.3 1 1 2 3 3 3 0 Intermediate filament protein eIF3_N PF09440.5 EMC95556.1 - 0.43 10.7 5.7 0.33 11.1 0.2 2.9 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain Spc42p PF11544.3 EMC95556.1 - 0.45 10.4 5.4 0.45 10.4 0.0 3.2 3 1 1 4 4 4 0 Spindle pole body component Spc42p bZIP_1 PF00170.16 EMC95556.1 - 0.48 10.4 6.8 0.6 10.1 0.1 3.8 4 0 0 4 4 4 0 bZIP transcription factor NPV_P10 PF05531.7 EMC95556.1 - 0.65 10.2 9.6 1.4 9.1 0.4 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 EMC95556.1 - 0.7 9.2 6.2 1.4 8.2 0.3 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF904 PF06005.7 EMC95556.1 - 0.86 9.9 15.6 32 4.8 1.0 4.9 2 1 2 4 4 4 0 Protein of unknown function (DUF904) ADIP PF11559.3 EMC95556.1 - 0.89 9.4 16.0 1.2 9.0 3.0 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.4 EMC95556.1 - 6.7 6.9 7.4 5.1 7.3 0.5 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.3 EMC95556.1 - 9.3 6.2 16.7 9.5 6.2 2.1 3.1 3 0 0 3 3 3 0 YlqD protein adh_short PF00106.20 EMC95558.1 - 5.2e-19 68.7 0.7 8.9e-12 45.2 0.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMC95558.1 - 6.1e-15 55.6 0.0 5.6e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC95558.1 - 1.5e-05 24.7 0.5 2.8e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EMC95558.1 - 0.00035 20.1 0.1 0.0012 18.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EMC95558.1 - 0.0039 17.2 0.5 0.0085 16.1 0.1 1.7 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EMC95558.1 - 0.014 14.6 0.9 0.027 13.7 0.4 1.6 2 0 0 2 2 2 0 NmrA-like family Shikimate_DH PF01488.15 EMC95558.1 - 0.03 14.4 0.1 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EMC95558.1 - 0.032 13.6 0.1 0.17 11.2 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3441 PF11923.3 EMC95559.1 - 8.5e-39 131.6 0.1 8.5e-39 131.6 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EMC95559.1 - 1.9e-28 99.2 18.3 1.9e-28 99.2 12.7 3.1 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EMC95559.1 - 1.2e-22 79.5 0.0 2.6e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF4080 PF13311.1 EMC95559.1 - 0.21 11.5 0.0 0.21 11.5 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4080) Redoxin PF08534.5 EMC95560.1 - 7.8e-33 113.0 0.1 8.9e-33 112.8 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMC95560.1 - 4.1e-14 52.3 0.1 6.3e-14 51.7 0.0 1.3 2 0 0 2 2 2 1 AhpC/TSA family AAA PF00004.24 EMC95562.1 - 4.9e-52 175.6 0.0 1.3e-39 135.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMC95562.1 - 2.2e-12 46.7 0.0 4.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 EMC95562.1 - 1.1e-10 41.8 0.1 0.00077 19.6 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMC95562.1 - 5.9e-10 39.4 0.0 0.00045 20.2 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.12 EMC95562.1 - 9.1e-10 38.0 0.1 1.2e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 EMC95562.1 - 3.6e-08 34.2 0.0 0.0027 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EMC95562.1 - 5.1e-08 32.8 0.0 0.0021 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EMC95562.1 - 5.4e-08 31.9 0.0 0.0077 14.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 EMC95562.1 - 1.5e-07 31.2 0.1 0.0015 18.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMC95562.1 - 2.4e-07 30.0 0.4 0.03 13.3 0.0 3.2 3 1 1 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMC95562.1 - 2.7e-07 30.6 0.0 7.3e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EMC95562.1 - 3.1e-07 30.0 0.6 0.016 14.9 0.0 3.3 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 EMC95562.1 - 6e-07 28.8 0.1 0.0047 16.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EMC95562.1 - 7.2e-07 29.5 0.1 0.005 17.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EMC95562.1 - 9.3e-07 28.8 0.0 0.033 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EMC95562.1 - 1.5e-06 27.9 0.9 0.0094 15.6 0.0 3.6 2 2 1 3 3 3 2 NACHT domain IstB_IS21 PF01695.12 EMC95562.1 - 1.8e-06 27.5 0.0 0.023 14.0 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 EMC95562.1 - 4.1e-06 26.3 0.1 0.24 10.8 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain RNA_helicase PF00910.17 EMC95562.1 - 5.2e-06 26.5 0.0 0.035 14.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EMC95562.1 - 6.9e-05 23.1 0.2 0.027 14.7 0.1 2.5 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 EMC95562.1 - 0.00011 22.0 0.5 2.3 7.8 0.0 3.3 2 1 1 3 3 3 2 Archaeal ATPase AAA_24 PF13479.1 EMC95562.1 - 0.0002 20.9 0.0 0.12 11.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMC95562.1 - 0.00036 20.5 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC95562.1 - 0.00039 19.5 0.0 0.61 9.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EMC95562.1 - 0.00044 19.7 0.5 0.84 8.9 0.0 3.3 2 2 1 3 3 3 1 AAA domain PhoH PF02562.11 EMC95562.1 - 0.0009 18.5 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein UPF0079 PF02367.12 EMC95562.1 - 0.0011 18.6 0.0 0.79 9.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 EMC95562.1 - 0.0012 18.4 0.0 0.44 10.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EMC95562.1 - 0.0016 17.3 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain KaiC PF06745.8 EMC95562.1 - 0.0038 16.3 0.1 0.13 11.3 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.1 EMC95562.1 - 0.0077 15.8 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EMC95562.1 - 0.0096 15.9 0.0 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.1 EMC95562.1 - 0.022 14.3 0.0 0.8 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EMC95562.1 - 0.024 13.5 0.0 0.3 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EMC95562.1 - 0.028 13.9 0.1 26 4.2 0.0 3.8 2 2 0 4 4 4 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.12 EMC95562.1 - 0.028 13.2 0.0 0.32 9.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 EMC95562.1 - 0.029 14.1 0.2 9.9 5.9 0.0 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.11 EMC95562.1 - 0.034 12.9 0.0 5.1 5.7 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase DUF815 PF05673.8 EMC95562.1 - 0.034 13.0 0.1 5.9 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EMC95562.1 - 0.042 13.3 0.0 12 5.3 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EMC95562.1 - 0.045 12.6 0.0 5.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 EMC95562.1 - 0.092 12.2 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.5 EMC95562.1 - 0.095 11.8 0.0 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Torsin PF06309.6 EMC95562.1 - 0.14 12.0 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Torsin KxDL PF10241.4 EMC95563.1 - 3.3e-30 103.8 2.5 4.4e-30 103.4 1.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein Flavi_NS4B PF01349.12 EMC95564.1 - 0.057 12.3 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B SURF6 PF04935.7 EMC95566.1 - 5.7e-48 163.0 36.8 5.7e-48 163.0 25.5 4.0 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EMC95566.1 - 3.6e-16 58.9 1.7 3.6e-16 58.9 1.2 6.3 4 2 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 Patatin PF01734.17 EMC95568.1 - 1.1e-25 90.7 0.0 1.8e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase PP-binding PF00550.20 EMC95569.1 - 5.4e-11 42.5 0.4 7.5e-11 42.1 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EMC95569.1 - 9.9e-06 25.5 0.1 1.4e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EMC95569.1 - 0.055 13.5 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) GPP34 PF05719.6 EMC95570.1 - 1.1e-66 224.8 0.2 1.5e-66 224.3 0.2 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SNF5 PF04855.7 EMC95571.1 - 2.8e-68 230.0 2.6 4.6e-68 229.3 1.8 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PHD PF00628.24 EMC95572.1 - 9.1e-15 54.0 16.5 2e-09 36.9 4.4 2.5 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 EMC95572.1 - 0.016 15.3 5.3 0.035 14.2 0.8 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.17 EMC95572.1 - 0.029 14.1 8.3 0.78 9.5 0.4 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Hormone_3 PF00159.13 EMC95572.1 - 0.043 13.8 0.1 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Pancreatic hormone peptide zf-PHD-like PF15446.1 EMC95572.1 - 0.091 12.0 7.2 0.88 8.8 0.7 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.6 EMC95572.1 - 2.2 8.3 7.8 2.7 8.0 0.2 2.5 2 0 0 2 2 2 0 RING-like domain PHD_2 PF13831.1 EMC95572.1 - 3.7 6.9 8.9 9.7 5.6 2.0 3.0 2 0 0 2 2 2 0 PHD-finger Peptidase_M24 PF00557.19 EMC95573.1 - 9.2e-13 48.2 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 FLO_LFY PF01698.11 EMC95573.1 - 0.23 10.2 3.0 0.4 9.4 2.1 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2457 PF10446.4 EMC95573.1 - 0.5 9.0 20.2 0.71 8.5 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EMC95573.1 - 1.3 8.6 13.3 59 3.1 9.4 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.6 EMC95573.1 - 1.7 8.4 10.0 1.1 9.0 5.3 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EMC95573.1 - 2.5 7.6 10.2 5.1 6.6 7.1 1.6 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EMC95573.1 - 7.4 6.2 8.5 12 5.5 5.9 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 EMC95573.1 - 9.9 6.5 20.6 23 5.3 14.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_20 PF00982.16 EMC95574.1 - 1.7e-147 491.7 0.0 2.3e-147 491.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EMC95574.1 - 6.1e-88 293.7 0.0 1.2e-87 292.7 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EMC95574.1 - 0.00012 21.7 0.0 0.07 12.6 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Fer4 PF00037.22 EMC95575.1 - 4.9e-14 51.2 14.3 3.4e-08 32.7 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EMC95575.1 - 6.9e-13 48.7 9.6 1.1e-12 48.1 6.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMC95575.1 - 2.6e-10 40.9 6.5 4.1e-05 24.2 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EMC95575.1 - 2.8e-10 40.2 9.9 5.4e-10 39.3 6.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMC95575.1 - 1.4e-09 37.6 22.0 9.9e-08 31.6 8.7 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMC95575.1 - 8.7e-09 35.2 19.8 9.3e-07 28.7 7.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EMC95575.1 - 9.5e-09 34.9 22.4 3.7e-06 26.6 8.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMC95575.1 - 1.6e-07 30.8 13.1 0.00095 18.9 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EMC95575.1 - 3.2e-07 29.9 15.2 0.0012 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EMC95575.1 - 1.1e-06 28.4 12.1 0.00058 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EMC95575.1 - 1.1e-05 25.6 9.1 0.015 15.7 0.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 EMC95575.1 - 1.5e-05 25.2 11.4 0.00017 21.8 8.2 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.2 EMC95575.1 - 0.008 16.6 17.4 0.017 15.6 2.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.1 EMC95575.1 - 0.0094 16.3 15.9 0.3 11.4 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EMC95575.1 - 0.012 16.1 13.9 0.33 11.5 1.3 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 EMC95575.1 - 0.21 11.7 4.2 0.33 11.0 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PAP_assoc PF03828.14 EMC95576.1 - 0.00013 21.8 0.1 0.00066 19.5 0.0 2.1 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMC95576.1 - 0.00029 21.1 0.0 0.00053 20.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Mid2 PF04478.7 EMC95578.1 - 0.058 12.8 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Med3 PF11593.3 EMC95578.1 - 0.45 9.6 5.0 0.58 9.3 3.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YtxH PF12732.2 EMC95578.1 - 0.98 9.8 6.4 5.9 7.3 2.4 2.5 2 0 0 2 2 2 0 YtxH-like protein Mito_carr PF00153.22 EMC95581.1 - 4.6e-61 202.5 7.2 6e-21 73.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Virul_fac_BrkB PF03631.10 EMC95582.1 - 0.46 9.7 14.0 0.18 11.1 6.0 2.2 2 0 0 2 2 2 0 Virulence factor BrkB CorA PF01544.13 EMC95583.1 - 7.3e-05 21.9 4.6 0.00014 21.0 3.2 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 EMC95583.1 - 0.14 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF485 PF04341.7 EMC95583.1 - 0.18 11.5 3.0 0.34 10.6 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF4381 PF14316.1 EMC95583.1 - 0.52 10.4 5.3 0.28 11.2 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4131 PF13567.1 EMC95583.1 - 3.8 6.8 7.0 8 5.8 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) EI24 PF07264.6 EMC95584.1 - 9.4e-05 21.9 14.8 0.00024 20.6 10.2 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Oxidored_q3 PF00499.15 EMC95584.1 - 0.0019 18.0 1.4 0.0045 16.7 1.0 1.7 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4231 PF14015.1 EMC95584.1 - 0.0064 16.4 1.7 0.013 15.4 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) DUF2207 PF09972.4 EMC95584.1 - 0.67 8.4 3.6 1.1 7.7 2.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2417 PF10329.4 EMC95584.1 - 1.4 8.2 5.0 2.4 7.4 3.5 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Vac14_Fig4_bd PF11916.3 EMC95585.1 - 2.8e-78 261.2 5.6 2.8e-78 261.2 3.9 2.3 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EMC95585.1 - 1.7e-46 156.5 1.3 1.1e-43 147.5 0.1 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EMC95585.1 - 1.5e-09 37.1 4.8 0.00022 21.0 0.0 7.3 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 EMC95585.1 - 2.5e-08 34.0 9.6 0.0012 19.0 0.0 5.9 7 0 0 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EMC95585.1 - 1.8e-07 31.4 11.2 0.00092 19.6 0.0 6.4 5 0 0 5 5 5 2 HEAT-like repeat ParcG PF10274.4 EMC95585.1 - 0.022 14.6 2.5 4.4 7.1 0.0 3.1 4 1 0 4 4 4 0 Parkin co-regulated protein Arm PF00514.18 EMC95585.1 - 0.023 14.5 3.0 13 5.7 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF4023 PF13215.1 EMC95585.1 - 0.1 12.3 0.2 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) tRNA-synt_2 PF00152.15 EMC95586.1 - 2e-69 233.9 0.0 3.1e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMC95586.1 - 6.1e-09 35.6 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMC95586.1 - 0.089 11.9 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Pyr_redox_dim PF02852.17 EMC95587.1 - 5.6e-40 135.7 0.1 1.7e-39 134.2 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EMC95587.1 - 2.2e-37 128.9 17.2 4.2e-36 124.7 11.9 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC95587.1 - 2.4e-22 79.1 12.1 3.4e-20 72.2 0.9 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC95587.1 - 3.9e-10 39.6 3.5 8e-06 25.8 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMC95587.1 - 1.3e-09 37.6 0.1 1.3e-09 37.6 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC95587.1 - 3.6e-08 33.6 1.5 1.2e-05 25.4 0.4 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC95587.1 - 1.3e-07 30.8 3.4 1.3e-07 30.8 2.3 2.7 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EMC95587.1 - 3.8e-07 29.3 16.4 0.00029 19.8 2.9 3.9 3 1 1 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.17 EMC95587.1 - 6.7e-07 28.5 3.4 6.7e-07 28.5 2.4 2.8 2 2 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EMC95587.1 - 2.1e-06 27.0 4.6 8.2e-06 25.0 0.1 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EMC95587.1 - 1.4e-05 23.7 16.2 8.7e-05 21.1 1.6 4.1 3 1 1 4 4 4 1 HI0933-like protein K_oxygenase PF13434.1 EMC95587.1 - 1.6e-05 23.9 0.7 0.14 11.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EMC95587.1 - 7.7e-05 22.3 4.0 0.013 15.0 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EMC95587.1 - 0.0011 18.0 2.1 0.013 14.4 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EMC95587.1 - 0.0052 15.8 11.4 0.37 9.7 1.0 3.7 3 1 1 4 4 4 2 FAD binding domain NAD_binding_7 PF13241.1 EMC95587.1 - 0.059 13.6 4.3 1.1 9.5 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EMC95587.1 - 0.6 10.0 0.0 0.6 10.0 0.0 2.5 3 0 0 3 3 3 0 NADH(P)-binding FMO-like PF00743.14 EMC95587.1 - 0.81 7.8 3.0 0.62 8.1 0.5 1.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.13 EMC95587.1 - 1.2 8.7 8.4 0.41 10.2 0.8 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EMC95587.1 - 1.5 7.3 6.2 0.28 9.7 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase COQ9 PF08511.6 EMC95588.1 - 4.2e-27 93.4 0.0 7e-27 92.7 0.0 1.3 1 0 0 1 1 1 1 COQ9 AA_permease_2 PF13520.1 EMC95589.1 - 1.7e-51 175.1 52.8 2e-51 174.8 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC95589.1 - 1e-25 90.0 43.0 1.6e-25 89.4 29.8 1.2 1 0 0 1 1 1 1 Amino acid permease Malic_M PF03949.10 EMC95590.1 - 6.1e-87 291.3 0.0 8e-87 290.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMC95590.1 - 3.9e-63 212.3 0.0 9.3e-63 211.0 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain DUF1828 PF08861.5 EMC95591.1 - 0.00097 18.7 0.2 0.028 14.0 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function DUF1828 DUF4449 PF14613.1 EMC95591.1 - 0.0014 18.5 3.3 0.0014 18.5 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) muHD PF10291.4 EMC95592.1 - 1.1e-63 214.8 0.0 1.6e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EMC95592.1 - 2.4e-09 37.2 0.0 7.8e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.13 EMC95592.1 - 0.0014 18.2 1.2 0.0022 17.5 0.9 1.2 1 0 0 1 1 1 1 BAR domain Laminin_II PF06009.7 EMC95592.1 - 0.05 13.3 0.9 0.11 12.2 0.6 1.6 1 0 0 1 1 1 0 Laminin Domain II Muted PF14942.1 EMC95592.1 - 0.78 9.6 3.2 1.7 8.5 2.2 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein HSP20 PF00011.16 EMC95593.1 - 1.6e-19 69.6 1.2 7.6e-14 51.4 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family RusA PF05866.6 EMC95593.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA SAGA-Tad1 PF12767.2 EMC95595.1 - 1.5e-39 136.2 0.0 2.1e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit NAD_binding_8 PF13450.1 EMC95596.1 - 3e-09 36.7 0.0 9.8e-09 35.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMC95596.1 - 4.9e-06 25.8 0.0 0.0003 19.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMC95596.1 - 0.00017 21.6 0.2 0.0015 18.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC95596.1 - 0.01 14.9 0.0 0.025 13.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EMC95596.1 - 0.014 15.1 0.2 0.19 11.5 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC95596.1 - 0.029 14.2 0.0 0.075 12.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC95596.1 - 0.03 13.4 0.1 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EMC95596.1 - 0.036 12.9 0.1 0.072 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EMC95596.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain TPT PF03151.11 EMC95598.1 - 1.6e-29 102.5 9.6 1.6e-29 102.5 6.6 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EMC95598.1 - 5.9e-10 38.5 19.3 2.1e-05 23.5 6.3 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EMC95598.1 - 0.00052 20.0 10.6 0.00052 20.0 7.3 2.6 3 0 0 3 3 3 2 EamA-like transporter family FmdE PF02663.9 EMC95598.1 - 0.056 13.3 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF914 PF06027.7 EMC95598.1 - 3.2 6.5 22.3 0.032 13.0 8.7 2.3 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) NSs PF11073.3 EMC95599.1 - 0.09 12.0 0.0 0.09 12.0 0.0 1.0 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like NYN PF01936.13 EMC95600.1 - 0.00096 19.4 0.0 0.0072 16.6 0.0 2.0 1 1 0 1 1 1 1 NYN domain Mito_carr PF00153.22 EMC95601.1 - 1.5e-46 155.9 1.3 2.7e-16 59.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Rab5ip PF07019.7 EMC95601.1 - 0.00035 20.6 0.5 0.0044 17.1 0.0 2.5 2 1 0 2 2 2 1 Rab5-interacting protein (Rab5ip) RRM_1 PF00076.17 EMC95602.1 - 2.8e-50 167.8 0.0 2.8e-16 58.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95602.1 - 1.1e-34 118.2 0.0 1.2e-10 41.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95602.1 - 4.7e-20 71.1 0.0 1.6e-05 24.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC95602.1 - 0.0006 19.6 0.0 1.9 8.3 0.0 3.4 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.3 EMC95602.1 - 0.0037 17.0 0.0 0.93 9.2 0.0 3.3 3 1 0 3 3 3 1 Limkain b1 DUF1777 PF08648.7 EMC95602.1 - 0.019 14.6 23.9 0.029 14.1 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) SAC3_GANP PF03399.11 EMC95606.1 - 6.9e-25 87.7 0.0 9.2e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMC95606.1 - 3.1e-19 69.1 0.0 4.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF2582 PF10771.4 EMC95606.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) CorA PF01544.13 EMC95607.1 - 0.0012 17.9 1.2 0.003 16.6 0.6 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Methyltransf_31 PF13847.1 EMC95608.1 - 4.2e-15 55.6 0.0 6.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC95608.1 - 1.7e-14 54.3 0.0 3.9e-14 53.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC95608.1 - 1.5e-12 47.5 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC95608.1 - 2.1e-11 44.1 0.0 3.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC95608.1 - 2.7e-10 40.6 0.0 4.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC95608.1 - 3.3e-08 33.8 0.0 5.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC95608.1 - 4.8e-07 29.1 0.0 6.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMC95608.1 - 0.00018 20.6 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EMC95608.1 - 0.0002 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EMC95608.1 - 0.00053 20.0 0.0 0.0025 17.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EMC95608.1 - 0.00078 18.3 0.0 0.0014 17.5 0.0 1.3 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EMC95608.1 - 0.0008 18.8 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EMC95608.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EMC95608.1 - 0.0036 16.7 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EMC95608.1 - 0.0056 15.8 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EMC95608.1 - 0.041 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 EMC95608.1 - 0.053 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase p450 PF00067.17 EMC95609.1 - 1.8e-29 102.6 0.0 3.7e-29 101.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L11_N PF03946.9 EMC95611.1 - 3.2e-26 90.5 0.1 7.4e-26 89.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EMC95611.1 - 1.2e-15 57.3 4.9 2.6e-15 56.3 2.1 2.4 2 1 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Fungal_trans PF04082.13 EMC95612.1 - 1.1e-13 50.7 0.1 2.6e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC95612.1 - 6.2e-06 26.0 13.3 1.3e-05 25.0 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAT PF02184.11 EMC95612.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat FRQ PF09421.5 EMC95613.1 - 2.8e-112 376.3 36.2 1.6e-103 347.3 18.8 3.0 2 1 0 2 2 2 2 Frequency clock protein Leu_zip PF15294.1 EMC95613.1 - 0.00052 19.2 0.2 0.001 18.2 0.1 1.4 1 0 0 1 1 1 1 Leucine zipper Herpes_BLRF2 PF05812.7 EMC95613.1 - 0.065 13.0 0.2 0.065 13.0 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Herpes_UL35 PF04496.7 EMC95613.1 - 0.075 13.2 0.1 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus UL35 family Patatin PF01734.17 EMC95615.1 - 8e-22 78.1 0.0 1.6e-20 73.9 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Epimerase PF01370.16 EMC95616.1 - 9e-16 58.0 0.3 2e-15 56.8 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC95616.1 - 4.9e-10 39.7 0.6 2.1e-09 37.6 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC95616.1 - 7.6e-08 31.8 0.1 1.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EMC95616.1 - 1.2e-07 30.7 0.0 1.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMC95616.1 - 6.6e-06 25.2 0.1 9.8e-06 24.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMC95616.1 - 0.00055 19.9 0.1 0.00092 19.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMC95616.1 - 0.00099 18.1 0.0 0.0048 15.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein MFS_1 PF07690.11 EMC95617.1 - 4.6e-22 78.2 76.2 9.6e-20 70.5 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EMC95618.1 - 1.5e-40 138.9 0.0 2.8e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC95618.1 - 7.2e-25 87.5 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Vac7 PF12751.2 EMC95619.1 - 7e-120 400.4 9.8 1.4e-119 399.4 6.8 1.4 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DNA_methylase PF00145.12 EMC95620.1 - 1.2e-33 116.6 0.0 2.6e-33 115.5 0.0 1.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EMC95620.1 - 3.4e-07 30.0 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 EMC95620.1 - 0.11 12.1 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain DUF2564 PF10819.3 EMC95621.1 - 1.9 8.6 8.0 0.41 10.7 1.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) DUF3359 PF11839.3 EMC95621.1 - 7 7.0 7.0 3.1 8.2 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) Sugar_tr PF00083.19 EMC95622.1 - 2.7e-78 263.5 29.6 3.5e-78 263.2 20.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC95622.1 - 1.4e-12 47.0 48.2 1.5e-11 43.5 17.7 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily S-AdoMet_synt_C PF02773.11 EMC95623.1 - 1.3e-75 251.7 0.1 2.3e-75 250.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EMC95623.1 - 1e-46 157.7 0.0 2e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EMC95623.1 - 2.7e-42 143.0 0.1 7.5e-42 141.6 0.1 1.8 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain WD40 PF00400.27 EMC95624.1 - 9.9e-14 50.6 0.4 0.016 15.1 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Cu_amine_oxid PF01179.15 EMC95625.1 - 4.5e-165 549.3 0.0 5.4e-165 549.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EMC95625.1 - 1.8e-07 31.1 0.1 3.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EMC95625.1 - 8.4e-06 25.7 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans_2 PF11951.3 EMC95626.1 - 7.6e-55 186.0 2.4 1e-54 185.6 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC95626.1 - 9.5e-10 38.2 12.5 1.5e-09 37.5 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EMC95626.1 - 0.038 13.6 4.1 0.084 12.5 2.8 1.6 1 0 0 1 1 1 0 AT hook motif SF3b10 PF07189.6 EMC95627.1 - 0.15 11.9 0.1 0.43 10.4 0.0 1.7 1 1 1 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) DUF3824 PF12868.2 EMC95628.1 - 6.4e-12 46.5 29.1 6.4e-12 46.5 20.1 9.6 7 3 3 10 10 10 3 Domain of unknwon function (DUF3824) RskA PF10099.4 EMC95628.1 - 0.087 12.5 5.9 0.67 9.6 0.6 3.2 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Ribosomal_L18e PF00828.14 EMC95630.1 - 9.9e-34 116.5 0.0 1.3e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PPR_2 PF13041.1 EMC95631.1 - 2.6e-06 27.2 0.0 1.9 8.5 0.0 5.4 5 1 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 EMC95631.1 - 3.6e-05 23.7 8.3 10 6.6 0.1 7.7 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 EMC95631.1 - 9.1e-05 22.1 0.6 1.2 9.2 0.0 5.6 6 0 0 6 6 6 1 PPR repeat TPR_14 PF13428.1 EMC95631.1 - 0.0013 19.1 1.9 3.6 8.4 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Ribosomal_S18 PF01084.15 EMC95632.1 - 3.6e-12 45.9 0.9 2.1e-11 43.5 0.0 2.5 3 0 0 3 3 3 1 Ribosomal protein S18 DUF1686 PF07937.6 EMC95634.1 - 0.013 15.1 0.3 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) Gti1_Pac2 PF09729.4 EMC95636.1 - 3.6e-50 170.0 0.6 1.9e-39 135.1 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Cnd1 PF12717.2 EMC95637.1 - 6.9e-54 182.3 2.6 2.4e-48 164.3 0.0 3.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EMC95637.1 - 1.1e-51 174.9 0.3 1.1e-51 174.9 0.2 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EMC95637.1 - 1.5e-11 44.4 7.5 0.0092 16.2 0.0 6.6 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EMC95637.1 - 2.7e-05 23.8 13.3 0.22 11.7 0.0 7.5 9 0 0 9 9 9 2 HEAT repeat DUF2435 PF10363.4 EMC95637.1 - 0.00019 21.2 0.0 1.9 8.4 0.0 4.0 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EMC95637.1 - 0.003 17.9 7.8 30 5.2 0.0 6.7 6 1 1 7 7 7 0 HEAT-like repeat Cohesin_HEAT PF12765.2 EMC95637.1 - 0.093 12.7 1.0 9.7 6.2 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Pkinase PF00069.20 EMC95638.1 - 8.5e-45 152.9 0.0 7.3e-25 87.5 0.1 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC95638.1 - 5.7e-14 51.8 0.0 3.1e-10 39.5 0.0 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EMC95638.1 - 0.00018 21.3 0.0 0.69 9.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC95638.1 - 0.028 13.3 0.0 6.6 5.5 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EMC95638.1 - 0.098 11.7 0.1 0.25 10.3 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CVNH PF08881.5 EMC95639.1 - 2.7e-27 94.9 0.2 3e-27 94.8 0.1 1.0 1 0 0 1 1 1 1 CVNH domain Pyridox_oxidase PF01243.15 EMC95641.1 - 5.1e-10 39.2 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EMP70 PF02990.11 EMC95642.1 - 6.7e-195 648.4 0.8 8.7e-195 648.1 0.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 bHLH-MYC_N PF14215.1 EMC95642.1 - 0.048 13.8 0.6 0.086 13.0 0.4 1.3 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal WD40 PF00400.27 EMC95643.1 - 1.8e-36 122.6 5.6 4.6e-08 32.6 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EMC95643.1 - 1.3e-28 98.8 12.7 2.3e-28 98.0 8.8 1.4 1 0 0 1 1 1 1 Sof1-like domain Cytochrom_D1 PF02239.11 EMC95643.1 - 0.034 12.4 0.0 0.085 11.1 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain EF-hand_7 PF13499.1 EMC95645.1 - 3.5e-26 91.1 11.7 7.4e-12 45.2 0.4 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EMC95645.1 - 1.7e-24 83.2 9.2 5.7e-08 31.5 0.1 5.1 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EMC95645.1 - 5.8e-23 78.6 3.7 3e-05 23.5 0.0 5.2 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 EMC95645.1 - 4.8e-18 63.6 11.0 1.9e-05 23.8 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 EMC95645.1 - 1.4e-16 59.7 5.5 8.6e-07 28.4 0.0 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EMC95645.1 - 1e-08 34.8 3.9 0.0049 16.5 0.1 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC95645.1 - 0.00074 19.3 0.4 0.1 12.5 0.0 3.5 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EMC95645.1 - 0.0016 18.0 0.9 0.65 9.7 0.0 3.9 4 1 1 5 5 5 1 EF hand SPARC_Ca_bdg PF10591.4 EMC95645.1 - 0.0032 17.4 1.7 1.3 9.0 0.1 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 EMC95645.1 - 0.049 13.6 0.1 10 6.1 0.0 3.2 3 1 1 4 4 4 0 EF hand S10_plectin PF03501.10 EMC95645.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain DAG_kinase_N PF14513.1 EMC95645.1 - 0.18 12.0 2.2 0.34 11.0 1.5 1.6 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF4485 PF14846.1 EMC95647.1 - 0.0022 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) Rhodanese PF00581.15 EMC95648.1 - 1.1e-11 45.0 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.8 EMC95650.1 - 6.8e-41 139.9 17.8 3.4e-37 127.6 11.7 2.6 2 0 0 2 2 2 2 DNA polymerase phi DUF3759 PF12585.3 EMC95650.1 - 0.028 14.3 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) RIH_assoc PF08454.6 EMC95650.1 - 0.13 11.8 0.0 0.4 10.3 0.0 1.8 1 0 0 1 1 1 0 RyR and IP3R Homology associated PCI PF01399.22 EMC95651.1 - 2e-20 73.0 1.1 7.4e-20 71.2 0.2 2.2 2 0 0 2 2 2 1 PCI domain DDRGK PF09756.4 EMC95651.1 - 0.00041 19.8 0.4 0.0009 18.7 0.3 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_16 PF13432.1 EMC95651.1 - 0.0018 18.9 8.8 1.9 9.2 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Med2 PF11214.3 EMC95651.1 - 0.021 14.8 1.4 0.064 13.3 0.1 2.4 2 1 0 2 2 2 0 Mediator complex subunit 2 TPR_21 PF09976.4 EMC95651.1 - 0.54 10.1 5.3 0.17 11.8 0.4 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.18 EMC95652.1 - 1.5e-20 73.2 0.0 2.7e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EMC95652.1 - 2.7e-18 66.2 0.0 7.8e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 EMC95652.1 - 8.1e-06 25.6 0.1 2.9e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC95652.1 - 0.002 18.0 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 EMC95652.1 - 0.0066 16.2 2.1 0.0066 16.2 1.4 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC95652.1 - 0.0079 16.2 2.9 0.0079 16.2 2.0 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC95652.1 - 0.02 14.5 0.2 0.02 14.5 0.1 2.2 2 0 0 2 2 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EMC95652.1 - 0.11 12.1 15.3 0.047 13.2 2.1 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EMC95652.1 - 0.21 11.3 14.2 0.062 12.9 2.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC95652.1 - 2.8 7.8 14.2 4.1 7.3 2.4 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMC95652.1 - 7.6 6.3 25.3 0.76 9.5 6.4 2.8 2 0 0 2 2 2 0 zinc-RING finger domain Gar1 PF04410.9 EMC95654.1 - 3.4e-22 78.5 0.6 3.5e-22 78.5 0.4 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 EMC95655.1 - 4.5e-87 292.7 18.5 5.2e-87 292.5 12.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3445 PF11927.3 EMC95656.1 - 1.2e-75 254.1 0.0 1.5e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Exo5 PF09810.4 EMC95657.1 - 1.3e-107 359.7 0.0 1.7e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EMC95657.1 - 3.5e-05 23.3 0.1 0.0009 18.6 0.1 2.5 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 EMC95658.1 - 2.9e-17 62.0 1.1 2.9e-17 62.0 0.8 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Histone PF00125.19 EMC95659.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC95659.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC95659.1 - 0.0042 17.0 0.4 0.0073 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC95659.1 - 0.039 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EMC95660.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EMC95660.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EMC95660.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC95660.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC95660.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMC95660.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T HAD_2 PF13419.1 EMC95661.1 - 3.7e-24 85.8 0.1 3.9e-23 82.5 0.1 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC95661.1 - 8.5e-10 39.3 0.0 1.1e-09 39.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC95661.1 - 2.3e-05 23.9 0.0 5.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF442 PF04273.8 EMC95661.1 - 0.14 11.9 0.0 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) MFS_1 PF07690.11 EMC95662.1 - 6.6e-36 123.7 19.8 6.6e-36 123.7 13.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC95662.1 - 6.6e-08 31.5 6.6 6.6e-08 31.5 4.6 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMC95662.1 - 0.00021 19.6 2.5 0.00033 19.0 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OSTbeta PF15048.1 EMC95662.1 - 0.062 13.3 0.0 0.062 13.3 0.0 1.6 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Corona_S2 PF01601.11 EMC95662.1 - 0.45 8.5 3.0 0.75 7.8 2.1 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ras PF00071.17 EMC95664.1 - 1.1e-51 174.3 0.1 5.6e-51 172.1 0.1 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC95664.1 - 3.8e-18 66.1 0.1 5.4e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC95664.1 - 0.00012 21.4 0.0 0.00089 18.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC95664.1 - 0.0022 17.4 0.1 1.1 8.6 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC95664.1 - 0.0083 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC95664.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC95664.1 - 0.05 12.8 0.0 0.76 9.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 EMC95664.1 - 0.064 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin SWI-SNF_Ssr4 PF08549.5 EMC95667.1 - 7.5e-115 384.7 7.7 8.5e-115 384.5 5.3 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) SET PF00856.23 EMC95669.1 - 0.054 13.8 0.0 1.9 8.7 0.0 2.4 1 1 1 2 2 2 0 SET domain KAR9 PF08580.5 EMC95670.1 - 1.4 7.0 10.4 1.9 6.6 7.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Abhydrolase_6 PF12697.2 EMC95671.1 - 1.4e-18 67.6 0.0 1.6e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC95671.1 - 1.8e-06 27.7 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PC4 PF02229.11 EMC95672.1 - 1.4e-19 69.0 0.1 4.6e-19 67.3 0.1 1.9 3 0 0 3 3 3 1 Transcriptional Coactivator p15 (PC4) adh_short PF00106.20 EMC95673.1 - 1.7e-25 89.8 0.1 2.8e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC95673.1 - 2e-16 60.5 0.0 2.2e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC95673.1 - 7e-10 38.8 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Mitovir_RNA_pol PF05919.6 EMC95673.1 - 0.15 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase BRCT PF00533.21 EMC95674.1 - 1.2e-05 25.3 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMC95674.1 - 0.002 17.9 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain MFS_1 PF07690.11 EMC95675.1 - 4e-30 104.7 56.2 2.6e-17 62.5 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC95675.1 - 8.6e-08 30.9 17.9 8.6e-08 30.9 12.4 2.6 1 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 EMC95675.1 - 8.1e-06 24.6 43.4 0.00045 18.9 11.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter 2OG-FeII_Oxy_2 PF13532.1 EMC95676.1 - 6.8e-35 120.6 0.0 8.9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EMC95676.1 - 0.00046 20.0 4.0 0.00081 19.2 2.8 1.4 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EMC95676.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pex2_Pex12 PF04757.9 EMC95678.1 - 0.068 12.5 0.5 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region 2Fe-2S_thioredx PF01257.14 EMC95680.1 - 4.9e-62 207.8 0.2 6.2e-62 207.4 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SBP_bac_7 PF03480.8 EMC95680.1 - 0.068 12.2 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 F-box-like_2 PF13013.1 EMC95681.1 - 0.037 13.7 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain ABC_tran PF00005.22 EMC95682.1 - 3.2e-34 118.1 0.0 6.4e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMC95682.1 - 3.3e-33 115.2 13.4 4.2e-33 114.9 9.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EMC95682.1 - 1.3e-07 31.8 0.1 0.0016 18.5 0.0 2.8 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EMC95682.1 - 9.7e-06 24.9 0.0 0.0063 15.7 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC95682.1 - 7e-05 22.8 0.0 0.0006 19.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMC95682.1 - 0.00031 21.5 0.0 0.00097 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC95682.1 - 0.00071 19.4 0.0 0.0082 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMC95682.1 - 0.00084 19.4 0.0 0.0053 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMC95682.1 - 0.0024 17.0 0.0 0.0046 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMC95682.1 - 0.0038 16.7 0.7 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 EMC95682.1 - 0.0068 16.6 0.0 0.057 13.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EMC95682.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMC95682.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EMC95682.1 - 0.027 13.8 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMC95682.1 - 0.031 13.7 0.0 0.06 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EMC95682.1 - 0.033 13.2 0.0 0.1 11.6 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EMC95682.1 - 0.042 13.7 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF1823 PF08853.6 EMC95682.1 - 0.044 13.5 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) AAA_28 PF13521.1 EMC95682.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EMC95682.1 - 0.078 13.3 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EMC95682.1 - 0.078 11.6 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 EMC95682.1 - 0.11 12.4 0.3 0.88 9.5 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EMC95682.1 - 0.13 11.1 0.0 0.29 9.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain WD40 PF00400.27 EMC95683.1 - 3e-24 83.9 17.9 3.7e-08 32.9 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat TMEM154 PF15102.1 EMC95684.1 - 0.00014 21.5 0.0 0.00014 21.5 0.0 2.4 1 1 1 2 2 2 1 TMEM154 protein family SKG6 PF08693.5 EMC95684.1 - 0.00031 20.0 0.0 0.00031 20.0 0.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EMC95684.1 - 0.0095 15.6 0.6 0.015 14.9 0.4 1.3 1 0 0 1 1 1 1 Rifin/stevor family DUF2029 PF09594.5 EMC95684.1 - 0.013 14.9 1.1 0.024 14.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) DUF2407_C PF13373.1 EMC95684.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Presenilin PF01080.12 EMC95684.1 - 0.094 11.5 6.6 0.15 10.8 4.6 1.2 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.6 EMC95684.1 - 0.92 8.6 2.6 1.5 7.9 1.8 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ashwin PF15323.1 EMC95684.1 - 1.4 8.8 13.5 7.9 6.4 9.7 2.0 2 0 0 2 2 2 0 Developmental protein DUF2413 PF10310.4 EMC95684.1 - 3.5 6.3 12.8 5.1 5.7 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PRP3 PF08572.5 EMC95685.1 - 9.5e-58 195.2 8.6 2.2e-57 194.0 5.9 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EMC95685.1 - 9.1e-36 122.3 0.0 2.7e-35 120.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PhzC-PhzF PF02567.11 EMC95686.1 - 9.7e-45 152.9 0.0 1.2e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Inp1 PF12634.2 EMC95687.1 - 3.4e-28 98.1 0.0 1.1e-27 96.4 0.0 1.9 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 EMC95688.1 - 3.1e-05 23.5 4.3 3.1e-05 23.5 3.0 3.3 1 1 0 3 3 3 1 Etoposide-induced protein 2.4 (EI24) zf-H2C2_2 PF13465.1 EMC95689.1 - 5.7e-11 42.1 6.8 3.5e-06 27.0 0.1 3.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC95689.1 - 1.3e-09 37.7 16.3 1.3e-05 25.2 0.8 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC95689.1 - 8.3e-07 28.9 13.9 0.00047 20.3 0.4 4.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC95689.1 - 0.00011 22.2 1.0 0.00011 22.2 0.7 4.2 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC95689.1 - 0.0014 18.7 6.4 0.012 15.7 0.2 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Bunya_G2 PF03563.8 EMC95689.1 - 0.0069 15.3 0.4 0.01 14.7 0.3 1.2 1 0 0 1 1 1 1 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.1 EMC95689.1 - 0.4 10.6 8.8 1.3 9.0 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 EMC95689.1 - 0.6 9.9 3.0 1.4 8.6 2.1 1.7 1 0 0 1 1 1 0 BED zinc finger PAP2 PF01569.16 EMC95690.1 - 1.1e-13 51.0 7.2 1.1e-13 51.0 5.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EMC95690.1 - 1.7e-09 37.4 5.5 3.7e-09 36.3 3.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily CYSTM PF12734.2 EMC95691.1 - 0.027 14.5 34.0 0.027 14.5 23.6 5.0 2 2 0 2 2 2 0 Cysteine-rich TM module stress tolerance Ribosomal_L18e PF00828.14 EMC95692.1 - 3.3e-23 82.4 0.0 6.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L7Ae PF01248.21 EMC95693.1 - 4.4e-25 87.0 0.0 5e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APP_Cu_bd PF12924.2 EMC95693.1 - 0.092 13.2 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD Ribosomal_L16 PF00252.13 EMC95694.1 - 1.5e-12 47.4 0.1 1.7e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Arylsulfotran_2 PF14269.1 EMC95695.1 - 1e-54 185.7 2.8 9.1e-47 159.6 0.2 2.2 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMC95695.1 - 6.6e-15 54.5 5.3 8.9e-15 54.1 2.7 1.8 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Hexapep_2 PF14602.1 EMC95695.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase ThiF PF00899.16 EMC95696.1 - 1.1e-38 132.1 0.0 2e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EMC95696.1 - 7.9e-26 89.4 2.1 3.1e-24 84.3 1.4 2.5 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EMC95696.1 - 1.3e-10 41.6 0.0 2.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EMC95696.1 - 0.0098 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3251 PF11622.3 EMC95696.1 - 0.12 11.7 0.2 5.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) PALP PF00291.20 EMC95697.1 - 3.5e-46 157.8 0.1 4e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hydantoinase_B PF02538.9 EMC95698.1 - 2.8e-200 666.0 0.5 7.3e-194 644.8 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMC95698.1 - 1.4e-94 316.5 0.4 3.3e-94 315.2 0.3 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMC95698.1 - 8e-59 198.0 1.9 1e-57 194.4 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DuoxA PF10204.4 EMC95699.1 - 0.0047 16.0 1.0 0.015 14.3 0.7 1.8 1 1 0 1 1 1 1 Dual oxidase maturation factor Abhydrolase_5 PF12695.2 EMC95700.1 - 1.4e-09 37.8 0.1 2.1e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC95700.1 - 1.5e-09 38.0 1.6 2.4e-09 37.4 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC95700.1 - 0.019 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_1 PF00561.15 EMC95700.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CPSF100_C PF13299.1 EMC95701.1 - 9.8e-39 133.1 0.3 9.8e-39 133.1 0.2 2.5 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EMC95701.1 - 1.4e-23 83.2 0.0 3.2e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EMC95701.1 - 0.00033 20.3 0.0 0.0025 17.4 0.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EMC95701.1 - 0.0049 16.6 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase DUF1814 PF08843.6 EMC95701.1 - 0.016 14.9 0.1 0.44 10.2 0.0 2.8 3 0 0 3 3 3 0 Nucleotidyl transferase of unknown function (DUF1814) CSTF2_hinge PF14327.1 EMC95702.1 - 8.2e-28 96.3 2.7 8.2e-28 96.3 1.9 2.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EMC95702.1 - 2.2e-21 75.2 0.1 3.4e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95702.1 - 8.6e-17 60.8 0.0 1.9e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95702.1 - 3.6e-10 39.5 0.0 5.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EMC95702.1 - 3.6e-08 32.5 3.8 3.6e-08 32.5 2.6 2.6 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Alpha-amylase PF00128.19 EMC95703.1 - 4e-55 187.4 0.2 5.6e-55 186.9 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EMC95703.1 - 3.2e-28 97.6 0.1 3.2e-28 97.6 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1966) DUF2850 PF11012.3 EMC95703.1 - 0.019 15.1 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) Glyco_hydro_70 PF02324.11 EMC95703.1 - 0.085 10.6 0.4 0.25 9.0 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 RNA_pol_Rpb1_5 PF04998.12 EMC95705.1 - 4.8e-89 298.3 0.0 1.1e-88 297.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EMC95705.1 - 4.3e-64 215.4 0.0 1.1e-63 214.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EMC95705.1 - 7.3e-32 110.9 0.0 4e-21 75.6 0.0 2.8 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EMC95705.1 - 1.4e-30 106.0 0.0 4e-30 104.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EMC95705.1 - 1e-19 70.2 0.0 4.5e-19 68.1 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rav1p_C PF12234.3 EMC95705.1 - 0.46 8.5 0.0 3 5.8 0.0 1.9 2 0 0 2 2 2 0 RAVE protein 1 C terminal peroxidase PF00141.18 EMC95707.1 - 9.5e-27 93.9 0.0 1.6e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FSH1 PF03959.8 EMC95708.1 - 1.4e-31 109.5 0.0 1.8e-30 105.9 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMC95708.1 - 1.8e-07 31.2 0.5 4.3e-06 26.7 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC95708.1 - 0.00089 19.0 0.0 0.0019 17.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family SR-25 PF10500.4 EMC95708.1 - 1.1 8.7 11.5 1.5 8.2 8.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MSA-2c PF12238.3 EMC95708.1 - 1.4 8.5 4.0 2.2 7.9 2.8 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Abhydrolase_6 PF12697.2 EMC95709.1 - 1.6e-11 44.5 0.1 2.3e-11 44.0 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC95709.1 - 0.048 13.2 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SH3_9 PF14604.1 EMC95710.1 - 9.2e-10 37.9 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC95710.1 - 1.1e-07 31.1 0.0 2.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC95710.1 - 1.9e-06 27.2 0.0 4.1e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain MtrF PF09472.5 EMC95710.1 - 0.038 13.2 0.9 0.078 12.2 0.6 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Apc3 PF12895.2 EMC95711.1 - 0.0028 17.7 0.6 0.0028 17.7 0.4 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 PCI PF01399.22 EMC95711.1 - 0.02 15.1 0.0 1.1 9.6 0.0 2.6 1 1 0 1 1 1 0 PCI domain Ppx-GppA PF02541.11 EMC95712.1 - 5e-42 144.0 0.0 6.9e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Rft-1 PF04506.8 EMC95714.1 - 1e-77 261.8 8.0 4.1e-41 140.9 4.5 3.0 2 1 0 2 2 2 2 Rft protein AIM24 PF01987.12 EMC95715.1 - 3.9e-40 137.6 0.0 5e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Acetyltransf_1 PF00583.19 EMC95716.1 - 2.5e-13 49.8 0.0 3.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC95716.1 - 1.3e-06 28.4 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC95716.1 - 0.00012 22.1 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC95716.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EMC95716.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain STAS PF01740.16 EMC95716.1 - 0.042 13.2 0.0 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 STAS domain Acetyltransf_CG PF14542.1 EMC95716.1 - 0.065 13.1 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase TPP_enzyme_N PF02776.13 EMC95716.1 - 0.087 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF2183 PF09949.4 EMC95717.1 - 1.3e-19 69.9 0.1 2.4e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Spc24 PF08286.6 EMC95718.1 - 1.3 8.6 5.2 0.5 10.0 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cwf_Cwc_15 PF04889.7 EMC95718.1 - 1.9 8.1 15.8 3.4 7.3 10.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.5 EMC95718.1 - 7 6.6 9.0 10 6.1 6.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 P22_Tail-4 PF11650.3 EMC95719.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor Glyco_hydro_cc PF11790.3 EMC95721.1 - 8.8e-69 231.5 0.4 1e-68 231.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NAD_binding_1 PF00175.16 EMC95722.1 - 9e-24 84.1 0.0 1.4e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMC95722.1 - 1.9e-18 66.3 0.0 3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMC95722.1 - 3.6e-09 36.6 0.0 2.8e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMC95722.1 - 0.097 12.6 0.0 0.45 10.4 0.0 2.0 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain 2OG-FeII_Oxy PF03171.15 EMC95724.1 - 2.7e-15 56.4 0.0 5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMC95724.1 - 2.4e-13 50.6 0.0 4.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PRP1_N PF06424.7 EMC95725.1 - 1.6e-51 174.1 6.1 4.8e-51 172.5 4.2 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EMC95725.1 - 2.5e-26 89.7 38.3 0.00013 22.3 0.4 14.8 5 3 10 15 15 14 10 Tetratricopeptide repeat TPR_16 PF13432.1 EMC95725.1 - 5.2e-24 84.3 23.1 5.6e-07 30.0 0.8 9.1 7 1 2 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMC95725.1 - 9.7e-23 80.2 23.4 2.9e-08 33.9 0.2 11.1 8 4 5 13 13 12 6 Tetratricopeptide repeat TPR_11 PF13414.1 EMC95725.1 - 7e-13 48.0 19.6 0.0015 18.0 0.1 9.5 5 5 5 11 11 11 4 TPR repeat TPR_2 PF07719.12 EMC95725.1 - 3e-12 45.4 18.1 0.66 10.0 0.0 11.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC95725.1 - 1.4e-08 33.9 0.0 8.8 6.3 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC95725.1 - 6.2e-06 26.0 15.3 6.3 7.2 0.0 10.6 10 3 3 13 13 12 1 Tetratricopeptide repeat TPR_15 PF13429.1 EMC95725.1 - 2.9e-05 23.2 29.4 0.0042 16.1 5.0 5.6 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC95725.1 - 6.7e-05 22.7 11.3 5.2 7.0 0.0 7.5 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC95725.1 - 8.6e-05 21.9 8.0 0.43 10.2 0.0 7.4 9 0 0 9 9 8 1 Tetratricopeptide repeat Suf PF05843.9 EMC95725.1 - 0.00014 21.6 5.1 0.26 10.9 0.0 4.6 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_9 PF13371.1 EMC95725.1 - 0.00029 20.6 4.9 4.2 7.2 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMC95725.1 - 0.00042 20.4 5.8 0.41 11.2 0.1 6.5 6 0 0 6 6 5 1 Tetratricopeptide repeat Cutinase PF01083.17 EMC95725.1 - 0.024 14.3 0.0 0.95 9.1 0.0 3.3 2 1 1 3 3 3 0 Cutinase PIN PF01850.16 EMC95725.1 - 0.16 12.3 6.3 28 5.0 0.0 4.7 4 1 0 4 4 4 0 PIN domain Fer4_13 PF13370.1 EMC95725.1 - 0.58 10.5 2.3 38 4.7 0.0 3.4 3 0 0 3 3 2 0 4Fe-4S single cluster domain TPR_6 PF13174.1 EMC95725.1 - 0.72 10.4 22.4 8.6 7.0 0.0 9.6 12 0 0 12 12 10 0 Tetratricopeptide repeat GST_N_3 PF13417.1 EMC95726.1 - 5.8e-11 42.4 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC95726.1 - 0.027 14.4 0.0 0.072 13.0 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ADH_zinc_N PF00107.21 EMC95727.1 - 2.7e-25 88.4 0.3 4.3e-25 87.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC95727.1 - 1.2e-21 76.5 0.2 2.4e-21 75.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Transp_cyt_pur PF02133.10 EMC95728.1 - 6.5e-94 314.9 41.8 7.7e-94 314.7 29.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tyrosinase PF00264.15 EMC95731.1 - 4.1e-52 177.5 11.0 7.4e-52 176.7 7.6 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase TPT PF03151.11 EMC95732.1 - 5.3e-32 110.5 11.8 5.3e-32 110.5 8.1 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EMC95732.1 - 0.00058 19.8 30.6 0.054 13.5 6.3 2.9 2 1 0 2 2 2 2 EamA-like transporter family EIF4E-T PF10477.4 EMC95732.1 - 0.14 10.9 0.7 0.19 10.4 0.5 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RRM_1 PF00076.17 EMC95733.1 - 5.7e-11 41.9 0.0 8.6e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95733.1 - 8.2e-07 28.9 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95733.1 - 2.1e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC95733.1 - 0.0042 16.8 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EMC95733.1 - 1 7.7 21.0 1.3 7.4 14.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NifU_N PF01592.11 EMC95734.1 - 3.1e-52 175.8 0.1 4e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Beta-lactamase PF00144.19 EMC95735.1 - 2.9e-43 148.1 0.6 4.3e-43 147.5 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase DOPA_dioxygen PF08883.6 EMC95736.1 - 2.3e-34 117.5 0.1 3e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Amino_oxidase PF01593.19 EMC95737.1 - 4.1e-28 98.6 0.0 6e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMC95737.1 - 3.4e-15 55.8 0.0 1.9e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC95737.1 - 1.2e-08 34.2 0.1 6.2e-08 31.9 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC95737.1 - 4.4e-05 23.8 0.0 0.011 16.1 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC95737.1 - 0.0003 19.9 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EMC95737.1 - 0.0088 16.1 0.0 0.041 13.9 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC95737.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC95737.1 - 0.096 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sua5_yciO_yrdC PF01300.13 EMC95738.1 - 7.2e-50 168.7 0.0 1.4e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EMC95738.1 - 7e-27 93.9 0.0 1.1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Peptidase_C15 PF01470.12 EMC95739.1 - 9.4e-12 45.1 0.0 6.8e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Pyroglutamyl peptidase MutS_V PF00488.16 EMC95740.1 - 9.3e-94 313.2 0.0 1.5e-93 312.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC95740.1 - 4.7e-38 131.0 0.4 1.1e-37 129.7 0.2 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EMC95740.1 - 1.2e-22 80.4 0.1 5e-22 78.4 0.1 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EMC95740.1 - 1.5e-16 60.2 1.1 7.1e-16 58.1 0.7 2.3 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EMC95740.1 - 1e-13 51.3 0.0 1.3e-12 47.7 0.0 2.5 2 0 0 2 2 2 1 MutS domain I Reo_sigmaC PF04582.7 EMC95741.1 - 0.54 9.3 5.1 3.8 6.5 2.3 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EMC95741.1 - 5 6.9 8.3 34 4.2 0.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PQ-loop PF04193.9 EMC95742.1 - 3.2e-26 90.6 8.5 4.4e-18 64.5 2.0 2.8 2 1 0 2 2 2 2 PQ loop repeat Band_7 PF01145.20 EMC95744.1 - 2.6e-28 99.1 2.8 4.9e-28 98.2 1.9 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMC95744.1 - 0.015 14.8 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family SNF2_N PF00176.18 EMC95746.1 - 1e-65 221.4 0.0 1.4e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EMC95746.1 - 4.6e-59 199.5 0.1 1.4e-58 197.9 0.2 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EMC95746.1 - 1.1e-12 47.6 0.0 4.5e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMC95746.1 - 2.3e-07 29.9 0.0 2.4e-06 26.6 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EMC95746.1 - 0.0032 17.3 0.0 0.017 14.9 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMC95746.1 - 0.072 13.2 0.0 0.63 10.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.19 EMC95747.1 - 3.3e-08 33.4 0.0 4.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC95747.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC95747.1 - 0.00015 21.8 0.1 0.00028 20.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMC95747.1 - 0.014 15.3 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1227 PF06777.6 EMC95749.1 - 1.6e-61 206.3 1.4 4.8e-61 204.7 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EMC95749.1 - 1.5e-50 171.0 0.1 2.7e-50 170.1 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EMC95749.1 - 3e-44 150.9 0.0 7.1e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EMC95749.1 - 0.00061 19.3 0.0 0.08 12.4 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EMC95749.1 - 0.008 14.9 0.0 0.07 11.9 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMC95749.1 - 0.015 15.1 0.0 0.1 12.4 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EMC95749.1 - 0.021 14.4 0.1 0.076 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 EMC95749.1 - 0.074 12.2 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein zf-RING_2 PF13639.1 EMC95750.1 - 6.1e-09 35.5 7.1 1.3e-08 34.4 4.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC95750.1 - 1.5e-07 31.3 3.2 3.6e-07 30.1 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EMC95750.1 - 2.5e-05 24.1 5.6 5.4e-05 23.0 3.9 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EMC95750.1 - 3.6e-05 23.5 2.2 8.4e-05 22.3 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EMC95750.1 - 0.0014 18.6 7.2 0.0034 17.3 5.0 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 EMC95750.1 - 0.0031 17.1 8.4 0.006 16.2 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EMC95750.1 - 0.0035 17.0 2.8 0.0035 17.0 1.9 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EMC95750.1 - 0.015 15.2 8.0 0.031 14.2 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Maf_N PF08383.6 EMC95750.1 - 0.041 13.4 0.8 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 Maf N-terminal region zf-C3HC4_3 PF13920.1 EMC95750.1 - 0.047 13.3 6.2 0.098 12.3 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMC95750.1 - 0.49 10.1 5.7 1 9.1 3.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EMC95750.1 - 0.97 9.0 3.9 4.1 7.0 2.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EMC95750.1 - 1.5 8.9 6.0 3.4 7.7 4.1 1.7 1 0 0 1 1 1 0 RING-like domain 3HCDH_N PF02737.13 EMC95751.1 - 1.4e-38 132.3 0.0 2e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMC95751.1 - 2.1e-11 44.0 0.0 5.3e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldh_1_N PF00056.18 EMC95751.1 - 0.0021 17.9 0.0 0.0044 16.8 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain DAO PF01266.19 EMC95751.1 - 0.0079 15.1 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC95751.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC95751.1 - 0.02 14.7 0.0 0.04 13.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC95751.1 - 0.026 14.5 0.1 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC95751.1 - 0.028 14.8 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EMC95751.1 - 0.043 12.9 0.0 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMC95751.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 EMC95751.1 - 0.43 10.3 1.9 1 9.1 0.1 2.4 2 1 1 3 3 3 0 FAD-NAD(P)-binding zf-Apc11 PF12861.2 EMC95752.1 - 0.0085 15.9 6.4 3 7.7 0.1 4.8 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 11 RING-H2 finger YabP PF07873.6 EMC95753.1 - 0.18 11.4 0.1 0.59 9.7 0.0 1.8 1 0 0 1 1 1 0 YabP family AMP-binding PF00501.23 EMC95754.1 - 2.1e-82 276.7 0.1 2.7e-82 276.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC95754.1 - 2.5e-12 47.5 2.0 4e-12 46.9 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DSBA PF01323.15 EMC95755.1 - 1.5e-39 135.5 0.0 1.7e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EMC95755.1 - 0.00033 20.7 0.1 0.0011 19.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 EMC95755.1 - 0.016 14.9 0.0 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Lipocalin_5 PF13924.1 EMC95756.1 - 2.7e-24 85.4 0.0 3.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain WD40 PF00400.27 EMC95757.1 - 2.9e-05 23.7 6.6 1.7 8.6 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EMC95757.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term VID27 PF08553.5 EMC95758.1 - 0 1092.0 0.1 0 1091.8 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein zf-H2C2_2 PF13465.1 EMC95759.1 - 6.1e-06 26.2 4.0 6.1e-06 26.2 2.8 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EMC95759.1 - 2.3e-05 24.4 11.5 0.0083 16.4 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC95759.1 - 3e-05 24.0 12.9 0.004 17.3 1.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger Coatomer_WDAD PF04053.9 EMC95760.1 - 3e-146 487.6 0.0 5.8e-146 486.7 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EMC95760.1 - 3.4e-78 263.0 0.0 4.7e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EMC95760.1 - 3.4e-49 163.0 11.8 3.2e-09 36.3 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMC95760.1 - 0.0057 14.8 6.6 0.92 7.5 0.0 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EMC95760.1 - 0.11 12.0 0.0 0.32 10.5 0.0 1.8 1 0 0 1 1 1 0 Region in Clathrin and VPS DUF3661 PF12400.3 EMC95761.1 - 1.4e-41 141.5 1.6 2.3e-41 140.9 1.1 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein FKBP_C PF00254.23 EMC95761.1 - 3.6e-30 103.8 0.0 5.6e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zn_clus PF00172.13 EMC95763.1 - 1.1e-08 34.8 10.6 1.9e-08 34.0 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.16 EMC95766.1 - 1.4e-40 138.5 3.5 2.8e-40 137.5 2.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Xylanase PF13201.1 EMC95766.1 - 0.044 12.6 1.0 0.13 11.0 0.1 2.3 1 1 1 3 3 3 0 Putative glycoside hydrolase xylanase Laminin_G_2 PF02210.19 EMC95766.1 - 0.049 13.6 0.1 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain Aldedh PF00171.17 EMC95767.1 - 5.6e-13 48.0 4.9 7.4e-12 44.3 1.9 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMC95767.1 - 0.1 11.8 0.1 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Glyco_hydro_20 PF00728.17 EMC95768.1 - 3.1e-82 276.5 0.0 3.9e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EMC95768.1 - 1e-21 77.9 0.0 2.1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EMC95768.1 - 4.5e-07 30.4 0.0 1.7e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 SIR2 PF02146.12 EMC95769.1 - 1.6e-57 194.0 0.0 2e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family SnoaL_2 PF12680.2 EMC95770.1 - 0.00067 20.0 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain DLH PF01738.13 EMC95770.1 - 0.0013 18.0 0.0 0.073 12.3 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family SnoaL PF07366.7 EMC95770.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Ank_2 PF12796.2 EMC95771.1 - 2.2e-06 27.9 0.2 6.5e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC95771.1 - 0.0044 17.5 1.0 2.5 8.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC95771.1 - 0.043 13.6 0.2 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat MBOAT PF03062.14 EMC95772.1 - 1.8e-33 116.0 22.5 1.8e-33 116.0 15.6 3.1 2 2 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EMC95772.1 - 1.2e-06 28.4 4.5 3.6e-06 26.9 3.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Herpes_capsid PF06112.6 EMC95772.1 - 0.0041 17.1 0.4 0.0083 16.1 0.3 1.5 1 1 0 1 1 1 1 Gammaherpesvirus capsid protein EmrE PF13536.1 EMC95772.1 - 1.2 9.3 17.9 0.19 11.9 6.1 2.6 2 0 0 2 2 2 0 Multidrug resistance efflux transporter SurE PF01975.12 EMC95773.1 - 6.1e-32 110.5 0.1 8.4e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Nup_retrotrp_bd PF10599.4 EMC95773.1 - 0.14 12.7 2.0 0.26 11.9 1.2 1.7 1 1 0 1 1 1 0 Retro-transposon transporting motif FSH1 PF03959.8 EMC95774.1 - 3e-36 124.8 0.0 3.7e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EMC95774.1 - 2.2e-05 24.2 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC95774.1 - 0.00029 20.7 2.0 0.33 10.8 0.3 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EMC95774.1 - 0.038 13.2 0.0 5.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family SHMT PF00464.14 EMC95775.1 - 7.6e-192 637.0 0.0 8.8e-192 636.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EMC95775.1 - 0.001 18.2 0.0 0.028 13.5 0.0 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase DUF2390 PF09523.5 EMC95776.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2390) MAD PF05557.8 EMC95777.1 - 1.8e-47 161.9 54.6 8.1e-47 159.7 37.8 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Rootletin PF15035.1 EMC95777.1 - 0.0012 18.8 8.6 0.0012 18.8 6.0 6.6 1 1 4 6 6 6 2 Ciliary rootlet component, centrosome cohesion ADIP PF11559.3 EMC95777.1 - 0.0061 16.4 5.9 0.0061 16.4 4.1 7.0 4 2 2 7 7 7 2 Afadin- and alpha -actinin-Binding HOOK PF05622.7 EMC95777.1 - 0.84 7.3 67.7 0.022 12.6 21.4 3.3 2 2 1 3 3 3 0 HOOK protein Arginase PF00491.16 EMC95778.1 - 2.4e-75 253.3 0.5 2.9e-75 253.1 0.4 1.0 1 0 0 1 1 1 1 Arginase family WD40 PF00400.27 EMC95779.1 - 1e-54 180.5 26.5 8.1e-08 31.8 0.1 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat Nup160 PF11715.3 EMC95779.1 - 0.00025 19.3 1.4 0.026 12.6 0.0 3.0 2 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EMC95779.1 - 0.00038 20.6 3.2 7.6 6.9 0.0 5.9 6 0 0 6 6 6 1 PQQ-like domain IKI3 PF04762.7 EMC95779.1 - 0.0046 14.8 0.1 0.056 11.2 0.0 2.5 3 0 0 3 3 3 1 IKI3 family PD40 PF07676.7 EMC95779.1 - 0.0082 15.7 1.5 1.6 8.5 0.0 4.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 EMC95779.1 - 0.021 14.9 7.0 0.041 14.0 0.2 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 EMC95779.1 - 0.04 13.6 2.3 0.087 12.6 0.3 2.6 2 0 0 2 2 2 0 Kelch motif DPPIV_N PF00930.16 EMC95779.1 - 0.046 12.3 0.2 0.96 7.9 0.0 2.9 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 EMC95779.1 - 0.083 11.6 6.7 1.9 7.1 0.1 3.7 2 1 1 4 4 4 0 Nup133 N terminal like AP_endonuc_2 PF01261.19 EMC95780.1 - 2.1e-29 102.3 1.4 3.1e-29 101.8 1.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel JmjC PF02373.17 EMC95781.1 - 5e-10 39.6 0.1 1e-09 38.6 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EMC95781.1 - 3.3e-08 33.0 7.8 3.3e-08 33.0 5.4 2.5 2 0 0 2 2 2 1 PHD-finger Cupin_8 PF13621.1 EMC95781.1 - 1.7e-07 31.0 0.1 3.6e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Cupin-like domain zf-CW PF07496.10 EMC95781.1 - 0.66 9.7 13.2 0.094 12.4 2.0 3.0 3 0 0 3 3 3 0 CW-type Zinc Finger Zn_clus PF00172.13 EMC95781.1 - 2.7 7.9 29.3 0.28 11.1 4.7 3.7 3 1 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain C1_4 PF07975.7 EMC95781.1 - 7.3 6.6 14.8 0.067 13.1 3.4 2.7 3 1 0 3 3 3 0 TFIIH C1-like domain PHD_2 PF13831.1 EMC95781.1 - 9.2 5.6 16.2 0.017 14.4 2.6 3.0 4 0 0 4 4 4 0 PHD-finger RRM_1 PF00076.17 EMC95782.1 - 2.4e-13 49.4 0.3 3.5e-12 45.7 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95782.1 - 6.6e-10 38.8 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95782.1 - 1.7e-07 30.9 0.1 2.5e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Carboxyl_trans PF01039.17 EMC95783.1 - 3.3e-78 263.2 0.0 4.3e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-CCCH PF00642.19 EMC95784.1 - 8.1e-10 38.1 11.3 5.8e-06 25.8 1.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMC95784.1 - 0.00043 20.1 14.7 0.096 12.7 2.4 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type RecR PF02132.10 EMC95788.1 - 1.1 8.7 3.7 2.3 7.7 2.6 1.5 1 0 0 1 1 1 0 RecR protein DUF3325 PF11804.3 EMC95789.1 - 0.019 14.9 4.1 0.029 14.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) ADH_zinc_N PF00107.21 EMC95790.1 - 5.8e-23 80.8 0.1 1.4e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC95790.1 - 3.1e-17 63.6 0.0 5.6e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC95790.1 - 4.1e-12 45.8 0.0 2.1e-09 37.0 0.0 3.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DUF987 PF06174.6 EMC95790.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF987) Peptidase_C2 PF00648.16 EMC95792.1 - 2e-59 201.0 3.3 1.2e-40 139.4 0.4 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Yippee-Mis18 PF03226.9 EMC95795.1 - 8.5e-22 77.0 0.0 1.4e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EMC95795.1 - 0.0019 18.0 0.1 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of RIG-I TF_Zn_Ribbon PF08271.7 EMC95795.1 - 0.082 12.2 0.1 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding Coiled PF05710.7 EMC95795.1 - 8.6 6.8 9.0 11 6.6 3.4 2.2 2 0 0 2 2 2 0 Coiled coil PDZ_1 PF12812.2 EMC95798.1 - 4.2e-48 161.1 0.0 2.6e-30 104.1 0.0 3.0 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EMC95798.1 - 1.2e-16 60.3 0.3 2.2e-07 30.6 0.0 3.7 3 0 0 3 3 3 2 PDZ domain Trypsin_2 PF13365.1 EMC95798.1 - 7.2e-14 51.8 0.0 8.3e-13 48.3 0.0 2.7 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ PF00595.19 EMC95798.1 - 1.1e-10 41.5 0.0 2.1e-05 24.6 0.0 3.1 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EMC95798.1 - 0.00015 21.3 0.0 0.00063 19.3 0.0 2.0 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EMC95798.1 - 0.0003 20.5 0.3 0.081 12.7 0.1 2.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EMC95798.1 - 0.1 11.9 0.1 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EMC95798.1 - 0.18 11.0 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 EMC95798.1 - 0.2 10.0 0.0 0.61 8.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase S46 GMC_oxred_N PF00732.14 EMC95799.1 - 1.6e-48 165.3 0.0 2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMC95799.1 - 0.00025 20.0 0.1 0.051 12.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMC95799.1 - 0.0005 19.1 0.2 0.0011 18.0 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMC95799.1 - 0.0013 18.8 0.1 0.36 10.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC95799.1 - 0.013 15.5 0.1 0.04 13.9 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC95799.1 - 0.024 13.5 0.4 1.4 7.7 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EMC95799.1 - 0.095 12.5 0.0 1 9.1 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC95799.1 - 0.1 12.3 0.6 0.76 9.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EMC95799.1 - 0.2 10.4 0.2 11 4.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NIF3 PF01784.13 EMC95800.1 - 8.6e-60 202.3 0.0 1.1e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EMC95801.1 - 4.4e-17 61.8 0.0 4.8e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein Pyr_redox_2 PF07992.9 EMC95802.1 - 2.4e-31 109.2 0.0 3.9e-31 108.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC95802.1 - 2.2e-10 40.7 0.0 1.9e-07 31.3 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC95802.1 - 1.1e-07 32.0 0.0 0.11 12.5 0.0 3.7 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_cc PF11790.3 EMC95804.1 - 2.2e-53 181.1 3.8 2.5e-53 180.9 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cellulase PF00150.13 EMC95804.1 - 0.012 14.8 0.3 0.31 10.2 0.0 2.2 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) PHO4 PF01384.15 EMC95806.1 - 1.1e-96 323.3 19.1 1.5e-96 322.8 13.2 1.2 1 0 0 1 1 1 1 Phosphate transporter family EpsG PF14897.1 EMC95806.1 - 0.0083 15.0 0.1 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 EpsG family Kelch_4 PF13418.1 EMC95808.1 - 9.9e-19 66.8 6.9 4.4e-08 32.7 0.1 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC95808.1 - 3.1e-16 59.0 10.7 6.6e-05 22.9 0.0 6.5 6 1 1 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC95808.1 - 2e-11 43.5 10.4 0.0098 15.8 0.0 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EMC95808.1 - 3.3e-10 39.3 0.1 0.089 12.3 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EMC95808.1 - 2.6e-09 36.4 0.7 0.049 13.4 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 EMC95808.1 - 1.4e-07 31.3 3.2 0.092 12.9 0.0 5.1 5 1 1 6 6 6 3 Kelch motif His_biosynth PF00977.16 EMC95809.1 - 3.6e-48 163.8 0.1 2.3e-47 161.1 0.1 2.3 2 1 0 2 2 2 1 Histidine biosynthesis protein GATase PF00117.23 EMC95809.1 - 2.5e-27 95.5 0.0 4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EMC95809.1 - 1.5e-08 34.4 0.0 6.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EMC95809.1 - 7.2e-06 25.6 0.0 2.1e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EMC95809.1 - 0.0066 15.9 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Dus PF01207.12 EMC95809.1 - 0.015 14.1 0.1 0.027 13.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EMC95809.1 - 0.095 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase S4 PF01479.20 EMC95810.1 - 1.2e-12 47.0 0.0 2.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EMC95810.1 - 1.4e-08 35.0 0.1 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF111 PF01969.12 EMC95811.1 - 0.023 13.5 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 K_trans PF02705.11 EMC95812.1 - 1.4e-175 584.7 14.4 1.6e-175 584.4 10.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter IMS PF00817.15 EMC95815.1 - 7.2e-39 132.9 0.0 1.4e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMC95815.1 - 1.4e-18 67.0 0.0 3.5e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EMC95815.1 - 3.1e-16 59.2 4.3 2.1e-07 30.7 0.0 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4414) PTCB-BRCT PF12738.2 EMC95815.1 - 6.8e-05 22.6 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EMC95815.1 - 0.00057 19.7 2.6 0.0017 18.3 0.1 3.2 3 0 0 3 3 3 1 IMS family HHH motif BRCT PF00533.21 EMC95815.1 - 0.00072 19.6 0.0 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MgtE_N PF03448.12 EMC95815.1 - 0.055 13.7 1.3 57 4.1 0.0 3.9 4 0 0 4 4 4 0 MgtE intracellular N domain HHH_5 PF14520.1 EMC95815.1 - 0.06 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ada_Zn_binding PF02805.11 EMC95816.1 - 2.6e-33 113.3 3.7 3.6e-33 112.9 2.6 1.2 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EMC95816.1 - 2.4e-07 30.3 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EMC95816.1 - 3.4e-06 27.0 0.3 6.9e-06 26.0 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Flavin_Reduct PF01613.13 EMC95817.1 - 6.7e-16 58.5 0.0 9e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EMC95817.1 - 2e-08 33.9 0.0 2.6e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF447) LRR_4 PF12799.2 EMC95818.1 - 9.7e-53 175.0 60.0 3.8e-08 32.7 0.7 13.6 5 2 8 14 14 14 14 Leucine Rich repeats (2 copies) PP2C PF00481.16 EMC95818.1 - 6.2e-51 173.2 0.0 1.2e-50 172.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EMC95818.1 - 3.5e-42 141.9 52.0 4.6e-11 42.3 1.3 11.0 5 3 4 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.15 EMC95818.1 - 1.1e-28 99.9 0.0 2.3e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EMC95818.1 - 1e-23 79.7 54.7 0.036 14.0 0.1 19.0 17 3 1 18 18 18 7 Leucine Rich Repeat LRR_7 PF13504.1 EMC95818.1 - 2.2e-12 44.9 55.3 0.028 14.5 0.2 17.3 17 0 0 17 17 17 3 Leucine rich repeat RA PF00788.18 EMC95818.1 - 9.1e-11 42.1 0.0 3e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 EMC95818.1 - 1.6e-08 33.7 0.0 5e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.1 EMC95818.1 - 1.6e-08 33.7 45.9 2.8 8.2 0.2 16.8 18 0 0 18 18 18 2 Leucine Rich repeat Baculo_PEP_N PF04512.7 EMC95818.1 - 0.048 13.6 0.1 22 5.1 0.0 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus MscS_TM PF12794.2 EMC95819.1 - 0.054 12.1 0.5 0.098 11.2 0.3 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 NAM-associated PF14303.1 EMC95819.1 - 0.14 12.4 4.7 0.035 14.4 1.0 1.6 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain MOSC PF03473.12 EMC95820.1 - 3.1e-15 55.8 0.0 5.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EMC95820.1 - 7.7e-15 54.6 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2399 PF09664.5 EMC95820.1 - 0.041 13.7 0.1 0.095 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) Toprim_2 PF13155.1 EMC95820.1 - 0.11 12.8 0.0 0.61 10.4 0.0 2.0 1 1 1 2 2 2 0 Toprim-like UCR_hinge PF02320.11 EMC95821.1 - 0.088 12.7 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Fungal_trans_2 PF11951.3 EMC95822.1 - 0.00013 20.7 0.1 0.00018 20.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EFhand_Ca_insen PF08726.5 EMC95822.1 - 0.0051 16.7 0.0 0.058 13.3 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Clat_adaptor_s PF01217.15 EMC95823.1 - 1.5e-56 190.1 0.7 1.7e-56 189.8 0.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Baculo_VP39 PF04501.7 EMC95823.1 - 0.05 12.6 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 Zn_clus PF00172.13 EMC95825.1 - 4.3e-08 32.9 14.9 8.9e-08 31.9 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 EMC95826.1 - 3.4e-14 53.2 0.0 6.5e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC95826.1 - 3.8e-07 29.9 0.0 6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC95826.1 - 0.0013 18.3 0.1 0.0038 16.8 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC95826.1 - 0.0066 15.6 0.1 0.72 9.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EMC95826.1 - 0.054 13.3 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase Ammonium_transp PF00909.16 EMC95828.1 - 7e-117 390.2 32.3 8.1e-117 390.0 22.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2207 PF09972.4 EMC95828.1 - 2 6.9 4.6 0.8 8.2 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Acetyltransf_1 PF00583.19 EMC95829.1 - 3.2e-15 55.9 0.0 4.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC95829.1 - 9.9e-10 38.4 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC95829.1 - 2.1e-09 37.5 0.0 2.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC95829.1 - 3.4e-09 36.3 0.0 5.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EMC95829.1 - 3.6e-08 33.6 0.0 4.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMC95829.1 - 9.4e-06 25.5 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC95829.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMC95829.1 - 0.0052 16.7 0.0 0.0091 15.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC95829.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LCAT PF02450.10 EMC95830.1 - 1.1e-94 317.5 0.0 1.4e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EMC95830.1 - 0.018 14.7 0.1 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family CPSase_L_D2 PF02786.12 EMC95831.1 - 6.5e-53 179.1 0.0 9.9e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EMC95831.1 - 1.4e-33 115.0 0.0 6.3e-33 112.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EMC95831.1 - 1e-27 96.4 0.1 2.9e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 EMC95831.1 - 3.1e-12 45.9 1.8 7.8e-12 44.6 1.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EMC95831.1 - 3.6e-12 46.4 0.0 7.6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC95831.1 - 3.4e-10 39.1 0.0 5.6e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMC95831.1 - 8.3e-06 25.3 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMC95831.1 - 0.00023 20.5 0.1 0.00071 18.9 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain DUF2118 PF09891.4 EMC95831.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RimK PF08443.6 EMC95831.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EMC95831.1 - 0.048 13.5 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain Polysacc_deac_1 PF01522.16 EMC95832.1 - 4e-20 71.6 0.0 6.2e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 EMC95832.1 - 0.091 10.7 0.0 0.15 10.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) APG9 PF04109.11 EMC95833.1 - 9.4e-132 439.3 1.5 1.4e-131 438.8 1.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF829 PF05705.9 EMC95834.1 - 8.7e-12 45.2 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Kinesin PF00225.18 EMC95835.1 - 1.1e-85 287.2 1.7 1.7e-85 286.7 1.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EMC95835.1 - 5.4e-05 22.6 0.3 0.014 15.0 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.2 EMC95835.1 - 0.0017 18.2 0.0 0.0062 16.4 0.0 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EMC95835.1 - 0.0061 16.7 0.5 0.0061 16.7 0.3 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain UPF0150 PF03681.10 EMC95835.1 - 0.32 10.6 2.5 0.81 9.3 1.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) Cation_efflux PF01545.16 EMC95836.1 - 7.3e-49 166.3 13.0 7.3e-49 166.3 9.0 3.1 2 1 0 2 2 2 1 Cation efflux family Zip PF02535.17 EMC95836.1 - 4.2e-08 32.5 38.8 8.6e-05 21.6 16.5 3.6 2 1 1 3 3 3 3 ZIP Zinc transporter Bax1-I PF01027.15 EMC95836.1 - 0.0029 17.2 5.1 0.0029 17.2 3.5 4.2 3 2 1 4 4 4 1 Inhibitor of apoptosis-promoting Bax1 Glyco_trans_1_4 PF13692.1 EMC95837.1 - 1.9e-24 86.3 0.0 4.8e-24 85.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMC95837.1 - 6.3e-05 23.1 0.5 0.00014 22.0 0.1 1.7 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EMC95837.1 - 9.7e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 SHNi-TPR PF10516.4 EMC95838.1 - 5.1e-14 51.2 0.8 5.1e-14 51.2 0.6 2.5 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 EMC95838.1 - 5.4e-06 26.2 4.7 0.052 13.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC95838.1 - 0.00015 21.2 10.1 0.0061 16.1 0.3 3.1 2 1 0 2 2 2 2 TPR repeat IncA PF04156.9 EMC95838.1 - 0.021 14.4 2.5 0.034 13.7 0.0 2.3 1 1 0 2 2 2 0 IncA protein TPR_16 PF13432.1 EMC95838.1 - 0.029 15.0 0.1 0.029 15.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_13 PF13166.1 EMC95838.1 - 8.2 4.7 17.9 7.1 4.9 0.6 2.8 2 1 0 2 2 2 0 AAA domain AA_permease_2 PF13520.1 EMC95839.1 - 1e-09 37.4 13.0 1.1e-09 37.3 9.0 1.0 1 0 0 1 1 1 1 Amino acid permease EI24 PF07264.6 EMC95839.1 - 2.2 7.6 8.9 0.54 9.6 1.0 2.3 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF883 PF05957.8 EMC95840.1 - 0.0013 19.0 16.6 0.023 15.0 1.2 2.7 1 1 0 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EMC95840.1 - 0.0058 16.1 14.2 0.042 13.3 9.4 2.5 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain YtxH PF12732.2 EMC95840.1 - 0.062 13.6 24.3 0.92 9.9 6.6 3.4 2 2 1 3 3 3 0 YtxH-like protein TROVE PF05731.6 EMC95840.1 - 0.42 9.3 9.5 0.57 8.8 6.6 1.1 1 0 0 1 1 1 0 TROVE domain DUF2215 PF10225.4 EMC95840.1 - 1.8 7.9 5.2 2.5 7.4 3.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Tape_meas_lam_C PF09718.5 EMC95840.1 - 3.8 7.5 5.8 16 5.4 0.3 2.7 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ISG65-75 PF11727.3 EMC95840.1 - 7.8 5.4 21.0 21 4.0 14.5 1.7 1 1 0 1 1 1 0 Invariant surface glycoprotein MNNL PF07657.8 EMC95841.1 - 0.034 14.0 0.3 0.038 13.9 0.2 1.1 1 0 0 1 1 1 0 N terminus of Notch ligand BTK PF00779.14 EMC95841.1 - 0.11 12.1 0.8 0.16 11.6 0.6 1.3 1 0 0 1 1 1 0 BTK motif MOZ_SAS PF01853.13 EMC95843.1 - 2.9e-61 205.9 0.0 3.9e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family HET PF06985.6 EMC95844.1 - 2.7e-10 40.5 4.4 2.7e-10 40.5 3.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Clat_adaptor_s PF01217.15 EMC95846.1 - 2.4e-14 53.2 1.7 2.5e-13 49.9 1.1 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.11 EMC95848.1 - 1.8e-37 128.8 23.8 1.8e-37 128.8 16.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EMC95848.1 - 0.023 15.1 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1772 PF08592.6 EMC95848.1 - 3.5 7.3 7.3 0.92 9.2 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Allantoicase PF03561.10 EMC95849.1 - 2.6e-99 328.9 0.0 1.8e-53 180.0 0.0 2.5 2 0 0 2 2 2 2 Allantoicase repeat Ank_2 PF12796.2 EMC95849.1 - 6.7e-18 64.8 0.0 2.2e-17 63.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DIL PF01843.14 EMC95849.1 - 1.5e-16 60.1 4.2 2.9e-15 56.0 1.3 2.8 2 1 0 2 2 2 1 DIL domain Ank PF00023.25 EMC95849.1 - 1.4e-14 53.0 0.0 5.5e-07 29.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMC95849.1 - 6.7e-14 51.6 0.2 2.5e-08 33.8 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC95849.1 - 2.3e-10 40.6 0.6 8.4e-06 26.1 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC95849.1 - 1e-09 37.6 0.0 0.00047 20.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat HATPase_c PF02518.21 EMC95850.1 - 4.8e-32 109.9 0.0 1.3e-31 108.5 0.0 1.8 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMC95850.1 - 3.9e-22 78.3 0.1 2.3e-21 75.9 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMC95850.1 - 3.3e-20 71.8 2.4 8e-20 70.6 0.0 2.9 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EMC95850.1 - 1.7e-12 47.7 1.9 3.7e-12 46.6 0.0 2.6 3 1 0 3 3 3 1 AAA ATPase domain GAF PF01590.21 EMC95850.1 - 7.6e-11 42.3 0.1 3.8e-10 40.0 0.0 2.3 3 0 0 3 3 2 1 GAF domain GAF_3 PF13492.1 EMC95850.1 - 1.4e-10 41.3 0.0 3.4e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EMC95850.1 - 1.9e-10 41.4 0.1 4.2e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EMC95850.1 - 4.3e-09 35.8 0.0 9.5e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain NACHT PF05729.7 EMC95850.1 - 9.9e-05 22.0 0.0 0.3 10.7 0.0 3.4 3 0 0 3 3 3 2 NACHT domain HATPase_c_3 PF13589.1 EMC95850.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_35 PF14516.1 EMC95850.1 - 0.0095 14.6 0.0 0.37 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 EMC95850.1 - 0.0098 16.0 0.0 0.35 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EMC95850.1 - 0.011 14.5 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 EMC95850.1 - 0.02 14.0 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_trans_4_3 PF12000.3 EMC95850.1 - 0.055 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group ArgK PF03308.11 EMC95850.1 - 0.12 11.1 0.1 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EMC95850.1 - 0.19 11.4 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B LCM PF04072.9 EMC95851.1 - 9.4e-29 100.2 0.0 1.3e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase UQ_con PF00179.21 EMC95851.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme RNA_pol_Rpb5_N PF03871.9 EMC95852.1 - 4.7e-28 97.4 0.0 6.2e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 EMC95852.1 - 0.0032 17.0 0.2 0.0073 15.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain AIRC PF00731.15 EMC95853.1 - 6.4e-56 187.8 1.8 1.2e-55 186.9 1.3 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EMC95853.1 - 2.7e-51 173.3 0.0 4.1e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EMC95853.1 - 5.5e-12 45.8 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMC95853.1 - 8.5e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMC95853.1 - 0.0003 20.2 0.0 0.0015 17.9 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 EMC95853.1 - 0.012 14.8 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.12 EMC95853.1 - 0.025 13.8 0.3 0.074 12.3 0.0 2.0 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Radical_SAM PF04055.16 EMC95853.1 - 0.026 14.7 0.1 0.2 11.8 0.0 2.3 2 1 1 3 3 3 0 Radical SAM superfamily XdhC_C PF13478.1 EMC95853.1 - 0.032 14.5 0.1 0.084 13.1 0.1 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain ATPgrasp_Ter PF15632.1 EMC95853.1 - 0.056 12.1 0.0 1.9 7.1 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon XPG_N PF00752.12 EMC95857.1 - 1.2e-29 102.4 0.0 1.2e-29 102.4 0.0 2.2 2 1 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EMC95857.1 - 1.5e-28 98.6 0.7 4.1e-28 97.2 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 EMC95857.1 - 4.6e-06 26.8 0.9 1.8e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.10 EMC95857.1 - 0.017 14.8 0.2 2.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain HXXSHH PF07586.6 EMC95857.1 - 0.6 8.9 6.1 1.2 8.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Acyl-CoA_dh_N PF02771.11 EMC95858.1 - 1.3e-22 80.5 0.1 2.2e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EMC95858.1 - 1.1e-21 77.4 0.2 1.9e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC95858.1 - 2.9e-16 58.7 0.0 6e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC95858.1 - 1.1e-05 25.7 0.2 2e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Aminotran_1_2 PF00155.16 EMC95859.1 - 0.0025 16.8 0.5 0.0045 15.9 0.4 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II CALCOCO1 PF07888.6 EMC95859.1 - 0.013 13.8 15.1 0.029 12.6 10.4 1.5 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.7 EMC95859.1 - 0.82 9.4 11.4 2.6 7.8 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Herpes_UL6 PF01763.11 EMC95859.1 - 6.6 4.7 13.3 9.7 4.2 3.9 2.9 2 1 1 3 3 3 0 Herpesvirus UL6 like TFIIIC_sub6 PF10419.4 EMC95860.1 - 3.6e-09 35.9 0.0 7.7e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 EMC95861.1 - 3.6e-10 38.4 0.1 3.6e-10 38.4 0.1 2.2 3 0 0 3 3 3 1 Plant protein of unknown function (DUF946) Exo_endo_phos PF03372.18 EMC95862.1 - 6.9e-17 62.2 0.3 1.1e-16 61.5 0.1 1.4 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Lectin_leg-like PF03388.8 EMC95865.1 - 4.6e-31 107.7 0.1 6.8e-31 107.1 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Reo_sigmaC PF04582.7 EMC95865.1 - 0.00015 21.0 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein GrpE PF01025.14 EMC95865.1 - 0.019 14.5 1.3 0.075 12.5 0.9 1.8 1 1 0 1 1 1 0 GrpE BAR PF03114.13 EMC95865.1 - 0.033 13.7 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 BAR domain PspA_IM30 PF04012.7 EMC95865.1 - 0.062 12.6 0.2 0.095 12.0 0.2 1.2 1 0 0 1 1 1 0 PspA/IM30 family HAUS5 PF14817.1 EMC95865.1 - 0.065 11.7 0.4 0.088 11.3 0.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Baculo_PEP_C PF04513.7 EMC95865.1 - 0.07 12.9 0.7 0.18 11.6 0.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EMC95865.1 - 0.072 12.5 0.2 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.6 EMC95865.1 - 0.098 13.0 0.3 0.35 11.2 0.2 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlxA PF14282.1 EMC95865.1 - 0.11 12.4 0.3 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 FlxA-like protein TraQ PF09679.5 EMC95865.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Syntaxin PF00804.20 EMC95865.1 - 0.11 12.6 0.8 0.21 11.7 0.6 1.5 1 0 0 1 1 1 0 Syntaxin HalX PF08663.5 EMC95865.1 - 0.12 12.3 0.2 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 HalX domain Band_7 PF01145.20 EMC95866.1 - 6.3e-24 84.8 3.1 6.3e-24 84.8 2.2 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 EMC95866.1 - 0.0076 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus DUF2763 PF10961.3 EMC95866.1 - 0.008 16.5 0.3 0.053 13.9 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2763) Indigoidine_A PF04227.7 EMC95867.1 - 8.7e-113 376.3 0.5 1.2e-112 375.8 0.3 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EMC95867.1 - 1.1e-17 64.1 1.2 8.7e-09 34.9 0.0 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase HHH_2 PF12826.2 EMC95867.1 - 0.12 12.2 0.1 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ribophorin_I PF04597.9 EMC95868.1 - 1.9e-117 392.4 0.1 2.1e-117 392.2 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I DRIM PF07539.7 EMC95869.1 - 4.2e-43 146.1 0.2 3.7e-40 136.5 0.0 4.4 4 0 0 4 4 4 2 Down-regulated in metastasis MMS19_N PF14500.1 EMC95869.1 - 3 7.0 11.1 0.32 10.2 0.2 4.9 7 0 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II CwfJ_C_2 PF04676.9 EMC95870.1 - 1.7e-23 82.9 2.7 2.9e-23 82.1 1.9 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EMC95870.1 - 3.8e-23 81.4 0.0 8.9e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Cullin PF00888.17 EMC95871.1 - 3e-132 442.1 0.4 3.7e-132 441.8 0.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMC95871.1 - 9.3e-28 95.8 0.3 3.1e-27 94.1 0.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.5 EMC95871.1 - 0.027 14.0 0.4 0.6 9.7 0.1 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain LptE PF04390.7 EMC95871.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide-assembly zf-DNL PF05180.7 EMC95872.1 - 1.6e-27 95.0 0.6 1.9e-27 94.7 0.4 1.1 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 EMC95872.1 - 0.0097 15.5 0.3 0.014 15.0 0.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EMC95872.1 - 0.011 15.4 0.5 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMC95872.1 - 0.021 14.4 0.6 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 EMC95872.1 - 0.028 14.0 1.3 4 7.1 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-DNA_Pol PF08996.5 EMC95872.1 - 0.029 13.7 0.2 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF2039 PF10217.4 EMC95872.1 - 0.07 13.1 0.1 0.086 12.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) HypA PF01155.14 EMC95872.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 EMC95872.1 - 0.26 11.1 5.3 3.9 7.3 3.9 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain RasGEF PF00617.14 EMC95873.1 - 3.4e-47 160.6 0.0 4.1e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain IBR PF01485.16 EMC95874.1 - 6.7e-22 77.1 50.8 8.6e-12 44.7 6.7 4.7 4 1 1 5 5 5 3 IBR domain zf-C3HC4_2 PF13923.1 EMC95874.1 - 1.7e-05 24.7 6.9 1.7e-05 24.7 4.8 4.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC95874.1 - 0.00014 21.5 6.7 0.00014 21.5 4.7 3.7 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EMC95874.1 - 0.00017 21.1 4.1 0.00017 21.1 2.8 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EMC95874.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 EMC95874.1 - 0.011 15.4 10.5 0.011 15.4 7.3 3.8 3 1 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC95874.1 - 0.015 14.9 2.7 0.015 14.9 1.9 4.5 4 0 0 4 4 4 0 RING-type zinc-finger Mo25 PF08569.6 EMC95877.1 - 2.8e-114 381.6 0.1 3.2e-114 381.4 0.0 1.0 1 0 0 1 1 1 1 Mo25-like HopW1-1 PF15457.1 EMC95877.1 - 0.11 11.5 0.1 0.45 9.4 0.0 1.8 2 0 0 2 2 2 0 Type III T3SS secreted effector HopW1-1/HopPmaA MFS_1 PF07690.11 EMC95878.1 - 1.1e-32 113.1 29.3 1.5e-32 112.7 19.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.15 EMC95879.1 - 8.4e-10 38.8 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMC95879.1 - 3.2e-07 30.9 0.0 6.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WW PF00397.21 EMC95882.1 - 0.00075 19.3 3.4 0.00075 19.3 2.4 2.1 2 0 0 2 2 2 1 WW domain DUF3485 PF11984.3 EMC95882.1 - 0.017 14.1 0.0 0.043 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) DUF2076 PF09849.4 EMC95882.1 - 0.42 10.6 2.5 0.65 10.0 1.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_trans_2_3 PF13632.1 EMC95883.1 - 1.4e-22 80.3 0.7 1.4e-22 80.3 0.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC95883.1 - 9.4e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF2417 PF10329.4 EMC95883.1 - 0.0027 17.1 0.4 0.0063 15.9 0.3 1.5 1 0 0 1 1 1 1 Region of unknown function (DUF2417) UIM PF02809.15 EMC95884.1 - 0.064 12.8 0.0 0.26 10.9 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif F-box-like PF12937.2 EMC95885.1 - 0.00026 20.6 0.1 0.0027 17.4 0.0 2.6 2 0 0 2 2 2 1 F-box-like NIF PF03031.13 EMC95886.1 - 5e-26 91.2 0.1 1.2e-25 90.0 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EMC95886.1 - 3.5e-07 30.2 0.1 1.1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMC95886.1 - 4.1e-06 26.5 0.0 8.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Glyco_hydro_20 PF00728.17 EMC95886.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Sec23_trunk PF04811.10 EMC95887.1 - 1.1e-68 231.2 0.0 1.6e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMC95887.1 - 4.4e-24 83.8 0.0 6.6e-23 80.1 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMC95887.1 - 1.2e-17 64.1 0.0 3.4e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMC95887.1 - 8.8e-17 60.3 5.6 1.6e-16 59.5 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMC95887.1 - 6.1e-08 32.2 0.0 1.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat MFS_1 PF07690.11 EMC95888.1 - 5.9e-40 137.0 62.9 4.1e-37 127.7 29.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 EMC95888.1 - 0.00016 20.3 0.4 0.00016 20.3 0.3 2.3 2 1 0 2 2 2 1 LacY proton/sugar symporter AA_permease_2 PF13520.1 EMC95889.1 - 1.5e-58 198.4 47.1 1.8e-58 198.0 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC95889.1 - 6.9e-19 67.5 38.2 1e-18 66.9 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_transf_20 PF00982.16 EMC95891.1 - 2.6e-197 655.9 0.0 3.1e-197 655.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EMC95891.1 - 0.0014 18.2 0.1 0.0069 15.9 0.0 2.1 3 0 0 3 3 3 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EMC95891.1 - 0.0034 17.5 0.0 0.0077 16.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EMC95891.1 - 0.014 14.8 0.3 0.29 10.5 0.1 2.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 NPIP PF06409.6 EMC95893.1 - 6.9 5.3 9.5 1.7 7.3 0.8 2.4 2 1 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) DUF3397 PF11877.3 EMC95894.1 - 0.89 9.5 9.5 2.9 7.9 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3397) Glyco_transf_8 PF01501.15 EMC95895.1 - 9.1e-08 31.7 0.1 3.2e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EMC95895.1 - 0.045 13.0 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative DnaJ PF00226.26 EMC95896.1 - 1.3e-26 92.1 3.7 2e-26 91.4 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMC95896.1 - 1.5e-14 53.7 19.3 2.7e-14 52.9 13.4 1.5 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EMC95896.1 - 6.7e-11 41.9 0.0 5e-10 39.1 0.0 2.3 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EMC95896.1 - 0.012 15.3 8.3 0.45 10.2 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 EMC95896.1 - 5.3 6.6 13.3 7.8 6.0 0.3 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain Rad21_Rec8_N PF04825.8 EMC95897.1 - 1.8e-34 118.0 0.0 2.9e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EMC95897.1 - 4.5e-06 25.7 0.1 1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF4545 PF15078.1 EMC95897.1 - 0.028 13.3 0.4 0.042 12.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) E1-E2_ATPase PF00122.15 EMC95899.1 - 8.2e-78 260.5 0.1 1.4e-77 259.8 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC95899.1 - 2.6e-36 124.8 0.1 6.8e-36 123.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMC95899.1 - 8.8e-32 111.2 0.0 5.8e-31 108.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMC95899.1 - 8.1e-18 63.6 0.1 1.5e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC95899.1 - 4.7e-15 56.2 0.0 4.3e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC95899.1 - 1.7e-14 53.5 0.0 3.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC95899.1 - 7.3e-06 25.7 0.2 0.00047 19.8 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_A24 PF01478.13 EMC95899.1 - 0.00025 21.1 0.0 0.23 11.6 0.4 3.0 2 1 0 2 2 2 1 Type IV leader peptidase family HAD_2 PF13419.1 EMC95899.1 - 0.2 11.8 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Cupin_1 PF00190.17 EMC95901.1 - 7.7e-10 38.3 0.0 9.1e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EMC95901.1 - 5.1e-05 22.6 0.0 6.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain ATP_bind_1 PF03029.12 EMC95902.1 - 7.8e-76 254.7 0.1 9.9e-76 254.4 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EMC95902.1 - 2.9e-06 28.1 0.0 6.6e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC95902.1 - 2.3e-05 24.3 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC95902.1 - 0.00069 19.7 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EMC95902.1 - 0.0009 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EMC95902.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.9 EMC95902.1 - 0.0021 17.7 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EMC95902.1 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EMC95902.1 - 0.0033 17.7 0.0 0.021 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMC95902.1 - 0.0033 17.5 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 EMC95902.1 - 0.0038 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMC95902.1 - 0.0046 16.4 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein GTP_EFTU PF00009.22 EMC95902.1 - 0.005 16.2 0.0 1.4 8.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EMC95902.1 - 0.0051 16.6 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EMC95902.1 - 0.0063 15.9 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EMC95902.1 - 0.0067 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.17 EMC95902.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EMC95902.1 - 0.0085 15.7 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EMC95902.1 - 0.0096 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMC95902.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EMC95902.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC95902.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 EMC95902.1 - 0.028 13.2 0.0 0.075 11.7 0.0 1.6 2 0 0 2 2 2 0 ArgK protein NTPase_1 PF03266.10 EMC95902.1 - 0.028 14.1 0.1 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 EMC95902.1 - 0.029 13.8 0.1 0.11 11.9 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EMC95902.1 - 0.03 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 EMC95902.1 - 0.031 14.2 0.0 0.07 13.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EMC95902.1 - 0.041 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EMC95902.1 - 0.051 12.7 0.0 0.1 11.7 0.0 1.5 2 0 0 2 2 1 0 Chromatin associated protein KTI12 Septin PF00735.13 EMC95902.1 - 0.054 12.5 0.0 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 EMC95902.1 - 0.055 12.8 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Thymidylate_kin PF02223.12 EMC95902.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.1 EMC95902.1 - 0.079 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EMC95902.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMC95902.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EMC95902.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 EMC95902.1 - 0.099 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 KaiC CbiA PF01656.18 EMC95902.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.9 EMC95902.1 - 0.13 11.2 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain His_Phos_1 PF00300.17 EMC95903.1 - 2.3e-17 63.5 0.0 3.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Herpes_gE PF02480.11 EMC95904.1 - 0.00036 18.9 0.1 0.00076 17.8 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Med4 PF10018.4 EMC95905.1 - 1.5e-21 76.6 0.4 3.3e-21 75.5 0.3 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Metallophos PF00149.23 EMC95906.1 - 9.9e-14 51.2 0.6 2e-13 50.1 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC95906.1 - 4e-05 23.5 0.0 0.00016 21.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TRP PF06011.7 EMC95907.1 - 5.8e-123 410.7 10.7 8e-123 410.2 7.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMC95907.1 - 6.8e-36 123.4 4.0 1.3e-35 122.5 2.8 1.5 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EMC95907.1 - 4.3e-05 23.7 0.7 8e-05 22.8 0.5 1.4 1 0 0 1 1 1 1 ML domain NEAT PF05031.7 EMC95907.1 - 0.062 13.3 0.8 31 4.5 0.0 3.1 3 0 0 3 3 3 0 Iron Transport-associated domain Baculo_11_kDa PF06143.6 EMC95907.1 - 0.75 9.1 5.7 3.2 7.1 1.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family EphA2_TM PF14575.1 EMC95907.1 - 2.1 8.8 5.0 9.1 6.7 0.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF1218 PF06749.7 EMC95907.1 - 4.1 7.9 11.0 0.66 10.4 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) HemY_N PF07219.8 EMC95907.1 - 4.1 6.9 7.3 34 4.0 2.0 2.9 2 0 0 2 2 2 0 HemY protein N-terminus FtsL PF04999.8 EMC95907.1 - 5.3 6.8 6.3 11 5.8 0.0 3.2 3 1 1 4 4 4 0 Cell division protein FtsL DUF4267 PF14087.1 EMC95908.1 - 7.6e-17 60.9 0.2 9.7e-17 60.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) CH PF00307.26 EMC95909.1 - 9.3e-57 189.7 0.0 2.9e-16 59.4 0.1 4.5 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC95909.1 - 0.00026 20.5 0.0 2.3 7.9 0.0 3.9 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_7 PF13499.1 EMC95909.1 - 0.0012 18.9 0.2 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC95909.1 - 0.074 12.9 3.5 0.36 10.8 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 EMC95909.1 - 0.18 11.1 0.6 4 6.9 0.1 2.7 2 0 0 2 2 2 0 EF hand GST_C_2 PF13410.1 EMC95910.1 - 2.9e-07 30.2 0.2 9.9e-06 25.3 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC95910.1 - 1.9e-05 24.7 0.0 5.3e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC95910.1 - 0.00023 21.2 0.1 0.00073 19.6 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC95910.1 - 0.0039 17.6 0.1 0.017 15.6 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.1 EMC95910.1 - 0.044 13.7 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC95910.1 - 0.1 12.6 0.0 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF1907 PF08925.6 EMC95913.1 - 2.1e-106 355.1 0.0 2.4e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) DLH PF01738.13 EMC95914.1 - 1e-29 103.4 0.0 1.3e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC95914.1 - 8e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC95914.1 - 0.09 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family UCH PF00443.24 EMC95915.1 - 2.2e-45 154.8 0.0 3.3e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC95915.1 - 2.1e-25 88.6 15.1 1.1e-20 73.4 1.1 3.9 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMC95915.1 - 1.1e-22 80.8 0.0 4.1e-22 78.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EMC95915.1 - 1e-20 72.8 0.2 2.6e-09 36.6 0.0 2.8 3 0 0 3 3 3 2 UBA/TS-N domain UBA_4 PF14555.1 EMC95915.1 - 0.031 13.7 0.0 0.092 12.2 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain Abhydrolase_6 PF12697.2 EMC95916.1 - 6.8e-29 101.3 0.0 8.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC95916.1 - 2.5e-22 79.5 0.0 3.9e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC95916.1 - 1.4e-07 31.3 0.0 1.8e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC95916.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 1 1 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 EMC95916.1 - 0.16 10.3 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Rep_fac-A_C PF08646.5 EMC95917.1 - 1.9e-54 183.3 8.3 9.8e-53 177.7 3.1 3.2 3 0 0 3 3 3 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 EMC95917.1 - 5.1e-22 77.5 0.2 1.2e-21 76.3 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EMC95917.1 - 1.1e-13 50.7 0.3 2.9e-08 33.4 0.0 4.3 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain Zn_clus PF00172.13 EMC95918.1 - 2.9e-08 33.4 8.5 2.9e-08 33.4 5.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC95918.1 - 6.9e-05 21.8 0.4 0.0001 21.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.24 EMC95919.1 - 5e-36 123.7 0.0 1.6e-22 79.8 0.0 3.6 2 2 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC95919.1 - 3.2e-28 97.3 0.2 4.8e-27 93.6 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EMC95919.1 - 0.019 14.0 0.0 0.019 14.0 0.0 3.0 2 1 2 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit DUF1675 PF07897.6 EMC95919.1 - 1.1 9.0 9.6 1.9 8.2 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) HK97-gp10_like PF04883.7 EMC95919.1 - 4.3 8.3 0.0 4.3 8.3 0.0 4.4 4 1 0 4 4 4 0 Bacteriophage HK97-gp10, putative tail-component Ist1 PF03398.9 EMC95920.1 - 1.3e-64 216.5 2.0 1.7e-64 216.2 1.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Mad3_BUB1_I PF08311.7 EMC95922.1 - 6.1e-43 145.6 0.4 2e-42 143.9 0.1 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EMC95922.1 - 1.5e-13 50.4 0.0 2.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC95922.1 - 5.8e-05 22.2 0.0 0.00011 21.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EMC95922.1 - 0.00048 19.9 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 APH PF01636.18 EMC95922.1 - 0.0096 15.6 1.9 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.27 EMC95923.1 - 1.9e-70 230.3 11.5 1.8e-11 43.4 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EMC95923.1 - 3.5e-10 38.6 0.0 0.0084 14.2 0.0 4.1 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EMC95923.1 - 1.1e-07 31.7 0.0 0.036 13.7 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 EMC95923.1 - 0.00091 18.2 0.1 1.4 7.7 0.0 3.2 1 1 3 4 4 4 2 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 EMC95923.1 - 0.0013 17.5 0.1 0.91 8.1 0.0 3.5 1 1 0 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 EMC95923.1 - 0.0049 16.4 0.3 9 6.0 0.0 4.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Str_synth PF03088.11 EMC95923.1 - 0.012 15.6 0.0 0.18 11.8 0.0 2.7 3 1 1 4 4 4 0 Strictosidine synthase DUF3312 PF11768.3 EMC95923.1 - 0.012 13.8 0.0 0.018 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) VID27 PF08553.5 EMC95923.1 - 0.077 11.2 0.2 0.43 8.7 0.0 2.2 3 1 1 4 4 4 0 VID27 cytoplasmic protein Hira PF07569.6 EMC95923.1 - 0.09 11.9 0.1 22 4.1 0.0 3.5 3 1 1 4 4 4 0 TUP1-like enhancer of split PCI PF01399.22 EMC95924.1 - 1.5e-05 25.2 0.0 5.2e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain FA_desaturase PF00487.19 EMC95925.1 - 2.5e-35 122.1 29.4 3.8e-35 121.5 20.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMC95925.1 - 1.3e-12 47.3 0.0 3.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFIID_20kDa PF03847.8 EMC95926.1 - 1.6e-22 79.5 0.0 2.1e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Asp PF00026.18 EMC95927.1 - 1.5e-109 366.0 0.1 1.8e-109 365.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC95927.1 - 3.3e-13 49.9 0.0 1.1e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMC95927.1 - 5e-05 23.7 0.0 0.26 11.8 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMC95927.1 - 0.0001 21.8 0.0 0.0017 17.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 EMC95927.1 - 0.023 14.7 0.1 0.13 12.4 0.1 2.3 2 1 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain gag-asp_proteas PF13975.1 EMC95927.1 - 0.13 12.0 0.1 13 5.6 0.0 2.7 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease GRAM PF02893.15 EMC95928.1 - 2.5e-26 91.0 1.9 3.9e-15 55.1 0.1 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EMC95928.1 - 1.9e-24 86.0 0.0 4e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EMC95928.1 - 2.2e-17 63.1 0.0 7e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC95928.1 - 2.4e-08 34.1 0.0 6.7e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EMC95928.1 - 0.00028 20.7 0.1 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EMC95928.1 - 0.0011 18.9 0.0 0.0031 17.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 EMC95928.1 - 0.0056 15.2 0.0 0.0099 14.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_9 PF15410.1 EMC95928.1 - 0.0059 16.7 0.2 0.025 14.7 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 EMC95928.1 - 0.03 14.3 0.0 0.089 12.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.5 EMC95928.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region NUDIX PF00293.23 EMC95929.1 - 1.6e-05 24.6 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain GatB_N PF02934.10 EMC95930.1 - 1.6e-97 325.9 0.0 2.1e-97 325.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EMC95930.1 - 2.4e-18 66.2 0.0 4.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 GatB domain DUF839 PF05787.8 EMC95931.1 - 0.11 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) LSR PF05624.9 EMC95931.1 - 0.37 10.5 3.4 0.7 9.6 2.3 1.5 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) RCR PF12273.3 EMC95931.1 - 6.6 7.3 11.0 3.1 8.3 4.8 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Arf PF00025.16 EMC95932.1 - 1e-44 151.8 0.0 1.2e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC95932.1 - 2.8e-19 69.0 0.0 3.2e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC95932.1 - 1.8e-11 44.5 0.0 3.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EMC95932.1 - 1.4e-08 34.1 0.0 1.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMC95932.1 - 2.6e-06 26.7 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC95932.1 - 2.8e-06 26.8 0.0 6.8e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC95932.1 - 1.7e-05 24.7 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EMC95932.1 - 6.9e-05 21.7 0.1 0.00012 20.8 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.18 EMC95932.1 - 0.011 15.5 0.0 0.076 12.8 0.1 2.0 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 EMC95932.1 - 0.021 14.1 0.3 0.05 12.8 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EMC95932.1 - 0.045 13.2 0.1 0.4 10.1 0.0 2.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb2_6 PF00562.23 EMC95933.1 - 1.2e-110 369.9 0.0 1.9e-105 352.7 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMC95933.1 - 1.7e-29 102.2 0.0 2.6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMC95933.1 - 1.4e-26 93.1 0.0 2.7e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EMC95933.1 - 2.6e-24 84.7 0.0 6.4e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EMC95933.1 - 8.5e-23 80.0 0.0 1.8e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EMC95933.1 - 5.9e-14 52.0 0.0 1.9e-13 50.4 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EMC95933.1 - 1.7e-05 24.7 0.0 4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PT-HINT PF07591.6 EMC95933.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Pretoxin HINT domain DUF2162 PF09930.4 EMC95934.1 - 0.062 12.4 0.0 0.064 12.3 0.0 1.0 1 0 0 1 1 1 0 Predicted transporter (DUF2162) Adaptin_N PF01602.15 EMC95935.1 - 4.4e-145 483.9 1.8 5.8e-145 483.5 1.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMC95935.1 - 2.4e-26 92.6 0.2 7.3e-24 84.5 0.1 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMC95935.1 - 9e-20 70.7 1.6 9.5e-10 38.6 0.0 5.2 3 1 4 7 7 7 3 HEAT repeats HEAT PF02985.17 EMC95935.1 - 4.6e-12 44.9 5.8 0.0067 16.4 0.0 6.5 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.1 EMC95935.1 - 1.1e-05 25.6 6.6 0.67 10.5 0.0 6.8 8 1 1 9 9 9 2 HEAT-like repeat UNC45-central PF11701.3 EMC95935.1 - 0.0013 18.3 0.1 0.13 11.8 0.1 2.7 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 EMC95935.1 - 0.0039 16.5 0.3 0.43 9.8 0.0 3.7 3 1 0 3 3 3 1 CLASP N terminal Arm PF00514.18 EMC95935.1 - 0.0063 16.3 3.4 4.5 7.2 0.1 5.0 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EMC95935.1 - 0.013 15.4 0.3 3.7 7.5 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Atx10homo_assoc PF09759.4 EMC95935.1 - 0.019 14.7 0.0 0.49 10.1 0.0 2.8 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain AF0941-like PF14591.1 EMC95935.1 - 0.15 12.1 1.5 0.34 10.9 0.7 1.8 2 0 0 2 2 1 0 AF0941-like RasGEF_N_2 PF14663.1 EMC95935.1 - 0.23 11.3 2.2 1.1 9.1 0.1 3.2 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ribosomal_S17 PF00366.15 EMC95937.1 - 2.8e-10 40.0 1.6 2.8e-10 40.0 1.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 Abhydrolase_6 PF12697.2 EMC95938.1 - 2.5e-18 66.7 1.1 9.8e-18 64.8 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC95938.1 - 5.8e-06 26.1 0.0 1.1e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC95938.1 - 1.1e-05 25.1 0.0 2.5e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold EHN PF06441.7 EMC95938.1 - 0.02 14.8 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Abhydrolase_2 PF02230.11 EMC95938.1 - 0.02 14.3 0.0 0.85 9.0 0.0 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EMC95938.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 EMC95938.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF1254 PF06863.7 EMC95938.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) Amidohydro_1 PF01979.15 EMC95939.1 - 2.8e-20 73.2 1.1 1.2e-17 64.6 0.8 3.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC95939.1 - 2.2e-13 50.8 0.4 6.9e-13 49.2 0.3 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMC95939.1 - 8.1e-09 35.1 0.0 2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC95939.1 - 1.1e-07 31.4 0.1 0.00015 21.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family DUF1917 PF08939.5 EMC95940.1 - 3.4e-46 157.9 0.0 4.1e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF615 PF04751.9 EMC95940.1 - 0.09 12.4 0.6 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF615) DNA_primase_S PF01896.14 EMC95941.1 - 2.2e-53 179.9 0.1 4e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit PI-PLC-X PF00388.14 EMC95942.1 - 1.9e-05 24.0 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Gly_transf_sug PF04488.10 EMC95943.1 - 6.1e-11 42.6 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMC95943.1 - 0.052 12.0 0.0 0.073 11.5 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EMC95943.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Cyt-b5 PF00173.23 EMC95944.1 - 4.4e-14 52.0 0.0 5.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.11 EMC95945.1 - 1.2e-32 113.0 31.3 1.2e-32 113.0 21.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1993 PF09351.5 EMC95946.1 - 5.5e-54 182.4 0.0 6.2e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DinB_2 PF12867.2 EMC95946.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 DinB superfamily PXA PF02194.10 EMC95948.1 - 2.7e-31 108.5 0.8 8.1e-31 107.0 0.0 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EMC95948.1 - 2.1e-17 63.1 0.1 2e-15 56.8 0.0 3.6 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EMC95948.1 - 5.1e-08 32.7 0.0 1.5e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 PX domain tRNA-synt_1b PF00579.20 EMC95949.1 - 2.5e-57 194.2 0.0 3.2e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MCM PF00493.18 EMC95950.1 - 3.4e-125 417.2 0.0 4.7e-125 416.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EMC95950.1 - 2.1e-32 112.2 40.4 2.1e-32 112.2 28.0 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EMC95950.1 - 1.4e-18 67.5 0.0 3.4e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMC95950.1 - 1.7e-08 33.8 0.0 1.9e-06 27.1 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMC95950.1 - 5.9e-06 26.0 0.1 2.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMC95950.1 - 0.00047 19.7 0.0 0.0029 17.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMC95950.1 - 0.0011 18.4 0.2 0.0075 15.7 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-TFIIB PF13453.1 EMC95950.1 - 0.21 10.7 1.1 0.45 9.7 0.8 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.15 EMC95951.1 - 3.1e-15 55.6 7.9 3.1e-15 55.6 5.5 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Aldo_ket_red PF00248.16 EMC95952.1 - 2.5e-54 184.0 0.0 2.8e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MIF4G PF02854.14 EMC95955.1 - 1.9e-23 83.0 0.1 1.6e-22 79.9 0.1 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EMC95955.1 - 4.1e-15 55.4 0.0 8.6e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 MA3 domain Nucleo_P87 PF07267.6 EMC95955.1 - 0.9 8.1 6.7 1.7 7.2 4.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SRP14 PF02290.10 EMC95956.1 - 9.8e-23 79.8 0.7 2.2e-22 78.7 0.0 1.9 2 1 0 2 2 2 1 Signal recognition particle 14kD protein DUF604 PF04646.7 EMC95957.1 - 0.14 11.3 0.1 5 6.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF604 Drc1-Sld2 PF11719.3 EMC95959.1 - 7e-80 269.2 15.2 8.3e-80 268.9 10.6 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein COG6 PF06419.6 EMC95960.1 - 1.3e-202 674.2 4.6 1.5e-202 674.1 3.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 EMC95960.1 - 0.00044 20.1 2.2 0.0012 18.6 0.3 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.6 EMC95960.1 - 0.006 16.4 2.0 0.006 16.4 1.4 2.4 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) DUF445 PF04286.7 EMC95960.1 - 0.017 14.6 4.9 0.47 9.9 0.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF445) RasGAP PF00616.14 EMC95963.1 - 2.3e-53 180.7 0.2 7.1e-53 179.2 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EMC95963.1 - 2.5e-30 105.0 1.6 2.5e-30 105.0 1.1 2.3 2 0 0 2 2 2 1 RasGAP C-terminus Nup54 PF13874.1 EMC95963.1 - 4.2 7.0 10.3 2.5 7.7 1.2 2.7 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Mis14 PF08641.7 EMC95965.1 - 1.5e-14 54.2 2.1 1.5e-14 54.2 1.4 1.8 1 1 1 2 2 2 1 Kinetochore protein Mis14 like Fib_alpha PF08702.5 EMC95965.1 - 0.025 14.7 1.1 1.7 8.7 0.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 EMC95965.1 - 0.043 12.2 1.6 0.047 12.1 1.1 1.1 1 0 0 1 1 1 0 AAA domain GIDA_assoc_3 PF13932.1 EMC95965.1 - 0.051 13.6 0.6 3 7.9 0.0 2.8 3 0 0 3 3 3 0 GidA associated domain 3 Occludin_ELL PF07303.8 EMC95965.1 - 0.53 11.0 5.0 1.3 9.7 0.4 3.0 1 1 2 3 3 3 0 Occludin homology domain HSCB_C PF07743.8 EMC95965.1 - 3.9 7.9 7.5 1.9 8.9 1.4 3.0 2 2 1 3 3 3 0 HSCB C-terminal oligomerisation domain UDP-g_GGTase PF06427.6 EMC95967.1 - 1.7e-61 207.2 0.0 3.1e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EMC95967.1 - 0.0033 16.8 0.1 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1772 PF08592.6 EMC95968.1 - 5.5e-25 87.7 1.2 8.8e-25 87.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MSC PF09402.5 EMC95969.1 - 1.7e-84 283.4 0.0 2.3e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EMC95969.1 - 1.3e-17 63.0 0.0 3.1e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.6 EMC95969.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein SKG6 PF08693.5 EMC95969.1 - 0.031 13.6 0.4 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF3350 PF11830.3 EMC95969.1 - 0.064 13.2 2.1 15 5.7 0.1 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) zf-RING_5 PF14634.1 EMC95970.1 - 0.00015 21.4 1.3 0.00062 19.4 0.9 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC95970.1 - 0.00029 20.5 0.5 0.00029 20.5 0.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC95970.1 - 0.0004 20.3 0.8 0.0004 20.3 0.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC95970.1 - 0.025 14.2 2.0 0.091 12.4 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC95970.1 - 0.026 14.1 0.4 0.026 14.1 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 EMC95970.1 - 0.07 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-ribbon_3 PF13248.1 EMC95970.1 - 0.078 12.2 5.0 3 7.1 0.1 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Ank PF00023.25 EMC95970.1 - 0.16 11.8 0.2 4.8 7.1 0.2 2.4 2 0 0 2 2 2 0 Ankyrin repeat Nudix_N_2 PF14803.1 EMC95970.1 - 0.45 10.2 5.4 0.29 10.8 0.2 2.8 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 EMC95970.1 - 0.56 9.7 4.5 8.1 6.0 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EMC95970.1 - 4.8 7.0 6.9 0.75 9.6 1.4 2.2 2 2 0 2 2 2 0 Double zinc ribbon DDHD PF02862.12 EMC95971.1 - 4.1e-69 232.8 0.1 1.1e-67 228.1 0.0 2.6 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.9 EMC95971.1 - 0.12 11.6 0.1 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LCAT PF02450.10 EMC95971.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase 4HBT PF03061.17 EMC95972.1 - 1.7e-10 40.8 0.1 3.2e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EMC95972.1 - 0.14 12.1 0.4 0.41 10.6 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4442) Crystall PF00030.14 EMC95973.1 - 0.0068 16.2 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Beta/Gamma crystallin KilA-N PF04383.8 EMC95975.1 - 3.9e-05 23.2 0.0 0.00053 19.5 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain DUF3563 PF12086.3 EMC95975.1 - 0.12 12.1 0.4 0.23 11.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) ODC_AZ PF02100.12 EMC95976.1 - 3.5e-23 81.1 0.0 5.3e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Myb_DNA-binding PF00249.26 EMC95977.1 - 4.4e-18 65.0 6.3 1.3e-12 47.5 0.6 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC95977.1 - 3.4e-14 52.6 7.9 5.1e-13 48.9 3.5 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EMC95977.1 - 8.4e-05 22.6 8.2 0.013 15.6 1.9 2.8 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EMC95977.1 - 0.012 15.7 2.9 2.8 8.2 0.1 2.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 EMC95977.1 - 0.045 13.6 8.2 1.1 9.1 1.7 3.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Anoctamin PF04547.7 EMC95978.1 - 0.0093 14.6 2.1 0.0093 14.6 1.5 1.6 2 0 0 2 2 2 1 Calcium-activated chloride channel DsbB PF02600.11 EMC95978.1 - 0.22 11.3 10.3 1.6 8.5 0.2 2.8 2 1 0 2 2 2 0 Disulfide bond formation protein DsbB DUF4131 PF13567.1 EMC95978.1 - 2.4 7.5 11.6 3.3 7.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1191 PF06697.7 EMC95980.1 - 0.0017 17.2 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 EMC95980.1 - 0.03 13.9 0.4 0.069 12.8 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain DUF605 PF04652.11 EMC95980.1 - 1.1 8.5 3.8 1.5 8.1 2.6 1.2 1 0 0 1 1 1 0 Vta1 like Yip1 PF04893.12 EMC95982.1 - 0.026 14.0 0.4 0.046 13.2 0.3 1.3 1 0 0 1 1 1 0 Yip1 domain Rick_17kDa_Anti PF05433.10 EMC95982.1 - 0.17 11.5 9.2 0.3 10.7 6.4 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EMC95982.1 - 1 9.0 9.8 1.9 8.1 6.8 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.1 EMC95982.1 - 2.8 7.6 6.6 5.2 6.7 4.6 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain HSP70 PF00012.15 EMC95983.1 - 0.00013 20.0 0.0 0.00024 19.1 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC95983.1 - 0.0049 15.5 0.0 0.042 12.4 0.0 2.2 2 1 0 2 2 2 1 MreB/Mbl protein Cir_N PF10197.4 EMC95987.1 - 0.0026 17.7 1.8 0.0026 17.7 1.2 2.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR RRM_1 PF00076.17 EMC95989.1 - 1.3e-34 117.5 0.4 1.3e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC95989.1 - 3.6e-29 100.5 0.1 1.1e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC95989.1 - 2.7e-12 46.3 0.1 9.6e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC95989.1 - 0.075 12.8 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RabGAP-TBC PF00566.13 EMC95992.1 - 3.9e-47 160.4 0.0 8.2e-47 159.4 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain dCMP_cyt_deam_1 PF00383.17 EMC95993.1 - 2.9e-24 84.6 2.1 4.9e-24 83.9 1.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region HR1 PF02185.11 EMC95993.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Hr1 repeat Myf5 PF12232.3 EMC95995.1 - 0.016 15.7 0.6 0.056 14.0 0.4 1.9 1 0 0 1 1 1 0 Myogenic determination factor 5 F-box-like PF12937.2 EMC95996.1 - 0.11 12.2 0.7 0.41 10.4 0.0 2.4 3 0 0 3 3 3 0 F-box-like DUF1100 PF06500.6 EMC95998.1 - 6.8e-15 54.5 0.0 9.2e-15 54.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EMC95998.1 - 1.9e-14 53.6 0.0 4.1e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC95998.1 - 6.3e-14 52.4 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMC95998.1 - 3.4e-05 23.4 0.0 0.00018 21.0 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 EMC95998.1 - 0.00021 20.7 0.0 0.00055 19.4 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EMC95998.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EMC95998.1 - 0.0066 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMC95998.1 - 0.047 12.9 0.1 0.12 11.5 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family USP8_dimer PF08969.6 EMC95998.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain MIT PF04212.13 EMC95998.1 - 0.081 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Esterase_phd PF10503.4 EMC95998.1 - 0.13 11.4 0.0 0.79 8.9 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EMC95998.1 - 0.16 11.4 0.2 2.1 7.8 0.0 2.3 2 1 0 3 3 3 0 alpha/beta hydrolase fold DUF1771 PF08590.5 EMC95998.1 - 0.99 9.4 4.9 6.7 6.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) OST3_OST6 PF04756.8 EMC95999.1 - 6.6e-21 74.5 3.2 9.5e-21 74.0 2.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Filament PF00038.16 EMC96000.1 - 4.2 6.7 68.0 8.7 5.7 34.4 3.0 1 1 1 2 2 2 0 Intermediate filament protein DUF2722 PF10846.3 EMC96001.1 - 4.9e-08 32.4 1.7 4.9e-08 32.4 1.2 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.13 EMC96002.1 - 1.2e-33 116.4 0.0 2.4e-33 115.4 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Tannase PF07519.6 EMC96003.1 - 1.1e-92 311.2 2.9 7.5e-92 308.4 2.0 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EMC96003.1 - 0.00018 21.4 0.0 0.00058 19.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC96003.1 - 0.019 14.1 0.1 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMC96003.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cytochrom_B561 PF03188.11 EMC96004.1 - 8.8e-17 61.2 10.2 8.8e-17 61.2 7.0 1.7 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 PepSY_TM_3 PF13706.1 EMC96004.1 - 0.033 13.5 2.1 1.6 8.2 0.3 3.1 2 0 0 2 2 2 0 PepSY-associated TM helix PepSY_TM_1 PF13172.1 EMC96004.1 - 0.079 12.7 1.1 1.3 8.9 0.0 2.8 2 0 0 2 2 2 0 PepSY-associated TM helix DUF3493 PF11998.3 EMC96004.1 - 1.1 9.2 5.7 0.63 9.9 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) ATP1G1_PLM_MAT8 PF02038.11 EMC96004.1 - 2.6 7.1 6.8 9 5.4 0.1 3.0 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family VTC PF09359.5 EMC96005.1 - 5.6e-101 337.2 0.1 5.6e-101 337.2 0.0 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EMC96005.1 - 8.2e-24 84.8 23.2 3.3e-23 82.8 10.4 3.7 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 EMC96005.1 - 2.7e-10 40.3 5.2 5.5e-10 39.3 3.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) RrnaAD PF00398.15 EMC96006.1 - 9.7e-57 191.9 0.0 1.7e-56 191.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMC96006.1 - 8.8e-10 38.6 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC96006.1 - 1e-06 28.4 0.0 4e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC96006.1 - 4.7e-06 27.1 0.0 9.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC96006.1 - 6.1e-05 22.4 0.0 9.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EMC96006.1 - 0.00048 19.7 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EMC96006.1 - 0.00099 19.5 0.0 0.0028 18.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC96006.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMC96006.1 - 0.0084 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.11 EMC96006.1 - 0.044 12.7 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 EMC96006.1 - 0.076 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EMC96006.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 IATP PF04568.7 EMC96007.1 - 4.3e-19 68.4 1.5 5.3e-19 68.1 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Hexokinase_2 PF03727.11 EMC96008.1 - 3.4e-88 294.9 0.0 6e-88 294.1 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EMC96008.1 - 2.6e-74 249.0 0.0 3.1e-73 245.4 0.0 2.3 3 0 0 3 3 3 1 Hexokinase Ribosomal_L19e PF01280.15 EMC96008.1 - 1.7e-48 164.1 11.3 1.7e-48 164.1 7.8 2.4 2 1 0 2 2 2 1 Ribosomal protein L19e DUF3554 PF12074.3 EMC96009.1 - 1e-68 232.2 2.5 7.2e-67 226.2 0.1 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EMC96009.1 - 7e-33 112.7 58.0 2.1e-08 34.3 0.1 15.9 7 5 8 15 15 15 9 HEAT repeats HEAT PF02985.17 EMC96009.1 - 1.6e-32 108.6 41.8 0.078 13.0 0.0 21.4 23 0 0 23 23 23 9 HEAT repeat HEAT_EZ PF13513.1 EMC96009.1 - 4.9e-29 100.0 71.6 0.00058 20.2 0.0 23.8 19 4 7 26 26 26 10 HEAT-like repeat ParcG PF10274.4 EMC96009.1 - 1.9e-11 44.2 0.2 0.0031 17.4 0.0 6.9 8 1 1 9 9 9 2 Parkin co-regulated protein CLASP_N PF12348.3 EMC96009.1 - 4.4e-11 42.5 0.0 0.052 12.9 0.0 7.2 5 2 2 7 7 7 2 CLASP N terminal Cnd1 PF12717.2 EMC96009.1 - 4.4e-10 39.6 0.1 0.018 14.9 0.0 8.3 7 2 1 10 10 10 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EMC96009.1 - 4.7e-10 39.7 0.0 3.6 8.0 0.0 9.2 8 3 2 11 11 11 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EMC96009.1 - 1.7e-05 23.4 17.9 0.34 9.1 0.2 8.0 9 1 1 10 10 10 3 Adaptin N terminal region UME PF08064.8 EMC96009.1 - 5.4e-05 23.1 0.3 10 6.1 0.0 6.7 6 2 3 9 9 9 1 UME (NUC010) domain HA2 PF04408.18 EMC96010.1 - 5.3e-19 68.1 0.1 1.3e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMC96010.1 - 2.2e-13 49.8 0.2 4.9e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC96010.1 - 2.1e-11 43.6 0.4 4.1e-11 42.6 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMC96010.1 - 1.5e-07 31.5 0.2 6.6e-07 29.5 0.1 2.2 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 EMC96010.1 - 2.9e-05 23.8 0.0 6.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HEM4 PF02602.10 EMC96011.1 - 4.2e-34 117.7 0.0 1.5e-33 115.9 0.0 1.8 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.8 EMC96012.1 - 2.8e-29 100.8 5.6 4.4e-29 100.2 2.4 1.9 2 0 0 2 2 2 1 Erv1 / Alr family Proteasome PF00227.21 EMC96014.1 - 8.5e-49 165.4 0.2 1e-48 165.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EMC96014.1 - 0.051 12.7 0.1 0.075 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) THOC7 PF05615.8 EMC96015.1 - 2.9e-28 98.8 10.0 2.9e-28 98.8 6.9 1.8 1 1 1 2 2 2 1 Tho complex subunit 7 CTD PF12815.2 EMC96015.1 - 0.0064 16.9 0.7 0.011 16.2 0.5 1.3 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF241 PF03087.9 EMC96015.1 - 0.27 10.6 6.7 1.9 7.9 4.6 2.0 1 1 0 1 1 1 0 Arabidopsis protein of unknown function SSFA2_C PF14723.1 EMC96015.1 - 0.47 10.1 6.2 0.95 9.1 4.3 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF4200 PF13863.1 EMC96015.1 - 4.3 7.2 15.4 13 5.7 10.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) HD PF01966.17 EMC96016.1 - 3.5e-09 36.7 0.7 6.2e-09 35.9 0.5 1.4 1 0 0 1 1 1 1 HD domain DNA_ligase_A_N PF04675.9 EMC96017.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA ligase N terminus TPP_enzyme_N PF02776.13 EMC96018.1 - 1e-36 125.9 1.3 4.6e-36 123.8 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMC96018.1 - 1.5e-22 79.7 0.3 5e-22 78.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMC96018.1 - 1.4e-15 57.2 0.0 3e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DLH PF01738.13 EMC96020.1 - 6.7e-18 64.7 0.0 7.2e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC96020.1 - 2.6e-09 36.9 0.2 3.5e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC96020.1 - 4.6e-06 26.6 0.3 0.00047 20.1 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family LAT PF15234.1 EMC96020.1 - 0.018 14.5 0.1 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells 3HCDH PF00725.17 EMC96020.1 - 0.086 13.2 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain polyprenyl_synt PF00348.12 EMC96021.1 - 2.1e-44 151.3 0.0 3.9e-44 150.4 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_28 PF00295.12 EMC96022.1 - 9.5e-87 290.9 22.4 1.2e-86 290.6 15.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EMC96022.1 - 3 7.5 51.9 4.2 7.1 29.0 3.4 2 1 1 3 3 3 0 Right handed beta helix region FKBP_C PF00254.23 EMC96023.1 - 7.6e-32 109.1 0.0 2e-31 107.8 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F1F0-ATPsyn_F PF10791.4 EMC96023.1 - 0.22 11.7 0.5 0.54 10.5 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Solute_trans_a PF03619.11 EMC96024.1 - 5.3e-41 140.7 15.7 4.9e-40 137.5 10.9 1.9 1 1 0 1 1 1 1 Organic solute transporter Ostalpha H_PPase PF03030.11 EMC96024.1 - 0.1 10.8 0.6 0.17 10.0 0.4 1.3 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Ferric_reduct PF01794.14 EMC96024.1 - 0.4 10.7 4.9 4.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Ferric reductase like transmembrane component DUF4293 PF14126.1 EMC96024.1 - 0.59 10.0 8.6 0.18 11.7 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Elicitin PF00964.12 EMC96027.1 - 0.031 14.2 0.2 0.038 13.9 0.1 1.1 1 0 0 1 1 1 0 Elicitin Spore_YtfJ PF09579.5 EMC96027.1 - 9.8 6.1 8.9 21 5.0 6.2 1.7 1 1 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) FUSC_2 PF13515.1 EMC96028.1 - 1.4e-26 92.8 5.0 1.4e-26 92.8 3.5 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EMC96028.1 - 2.2e-10 39.7 11.7 2.8e-07 29.5 5.3 3.0 2 1 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 EMC96028.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) FUSC PF04632.7 EMC96028.1 - 0.16 10.3 17.1 0.01 14.3 5.3 3.3 3 1 0 3 3 3 0 Fusaric acid resistance protein family DUF2422 PF10337.4 EMC96028.1 - 0.18 10.5 13.2 3.8 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2422) ER_lumen_recept PF00810.13 EMC96029.1 - 4.9e-53 179.5 2.7 6.7e-53 179.1 1.9 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EMC96029.1 - 0.52 9.8 9.6 3.2 7.3 0.2 3.4 4 0 0 4 4 4 0 PQ loop repeat TFIID-18kDa PF02269.11 EMC96030.1 - 2.2e-28 97.9 0.5 9.9e-28 95.7 0.2 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EMC96030.1 - 0.0026 17.8 0.2 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TP_methylase PF00590.15 EMC96031.1 - 5.7e-21 75.1 0.1 1.4e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2235 PF09994.4 EMC96032.1 - 3.4e-98 328.4 1.9 6.2e-98 327.5 1.3 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 EMC96034.1 - 1.6e-100 336.9 0.0 3e-98 329.5 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EMC96034.1 - 2.5e-08 32.8 0.0 4.7e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DWNN PF08783.6 EMC96035.1 - 2.8e-26 91.2 0.0 5.3e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EMC96035.1 - 1.4e-06 27.6 4.0 2.9e-06 26.6 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EMC96035.1 - 4.9e-05 23.2 6.1 4.9e-05 23.2 4.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC96035.1 - 0.00017 21.3 4.4 0.00039 20.1 3.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.3 EMC96035.1 - 0.00032 20.1 1.1 0.00084 18.8 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EMC96035.1 - 0.00032 20.3 2.0 0.00082 19.0 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ribbon_3 PF13248.1 EMC96035.1 - 0.0044 16.1 0.9 0.0044 16.1 0.6 2.5 2 0 0 2 2 2 1 zinc-ribbon domain zf-C3HC4 PF00097.20 EMC96035.1 - 0.0045 16.6 4.7 0.0092 15.6 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EMC96035.1 - 0.0069 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-CCHC_3 PF13917.1 EMC96035.1 - 0.0086 15.7 0.4 0.02 14.5 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EMC96035.1 - 0.017 15.0 3.5 0.017 15.0 2.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-RING_4 PF14570.1 EMC96035.1 - 0.027 14.0 4.4 0.061 12.9 3.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMC96035.1 - 0.07 13.0 6.9 0.17 11.8 4.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EMC96035.1 - 0.63 9.7 8.9 0.081 12.6 2.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GFA PF04828.9 EMC96035.1 - 0.74 9.8 4.0 3.7 7.5 0.0 3.0 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF572 PF04502.8 EMC96035.1 - 1.3 8.1 6.9 0.37 9.9 2.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) zf-RING_5 PF14634.1 EMC96035.1 - 1.8 8.3 10.6 0.11 12.2 3.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-dskA_traR PF01258.12 EMC96035.1 - 3.6 7.4 8.2 1.4 8.7 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger RED_N PF07808.8 EMC96036.1 - 4.3e-08 32.6 3.0 4.3e-08 32.6 2.1 1.6 2 0 0 2 2 2 1 RED-like protein N-terminal region ExoD PF06055.7 EMC96037.1 - 0.0094 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD PepSY_TM_2 PF13703.1 EMC96037.1 - 0.042 14.0 0.1 0.062 13.4 0.1 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix Vps16_N PF04841.8 EMC96039.1 - 0.11 11.0 0.2 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Ribosomal_L44 PF00935.14 EMC96040.1 - 8.3e-35 118.6 15.3 1.5e-34 117.8 8.5 2.3 2 0 0 2 2 2 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EMC96040.1 - 0.33 11.2 7.4 6.2 7.1 0.9 3.4 3 0 0 3 3 3 0 Ribosomal protein L33 HypA PF01155.14 EMC96040.1 - 5.8 6.6 8.6 4.8 6.9 0.1 2.5 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family RWD PF05773.17 EMC96041.1 - 0.0018 18.1 0.0 0.037 13.9 0.0 2.5 1 1 0 1 1 1 1 RWD domain Pkinase PF00069.20 EMC96043.1 - 2.6e-75 252.9 0.0 3.1e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC96043.1 - 4e-32 111.3 0.0 5.2e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC96043.1 - 0.00023 20.2 0.0 0.00066 18.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC96043.1 - 0.002 17.2 0.1 0.0034 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC96043.1 - 0.01 15.6 0.1 0.02 14.6 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMC96043.1 - 0.042 12.6 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MRJP PF03022.11 EMC96044.1 - 1.3e-27 96.7 0.0 1.8e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EMC96044.1 - 9.2e-05 21.9 0.2 0.00092 18.6 0.0 2.3 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Helicase_C_2 PF13307.1 EMC96045.1 - 6.6e-55 185.5 0.0 1.2e-54 184.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EMC96045.1 - 4.5e-46 156.4 0.0 8.2e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EMC96045.1 - 0.00077 19.3 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC96045.1 - 0.013 14.9 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 EMC96045.1 - 0.13 12.3 0.0 7.2 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain FinO_N PF12602.3 EMC96045.1 - 0.34 11.2 2.2 0.38 11.0 0.0 2.3 3 0 0 3 3 3 0 Fertility inhibition protein N terminal Vma12 PF11712.3 EMC96046.1 - 5.9e-37 126.5 0.0 8e-37 126.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Sensor PF13796.1 EMC96046.1 - 0.11 12.0 1.9 0.21 11.1 1.3 1.6 1 1 0 1 1 1 0 Putative sensor polyprenyl_synt PF00348.12 EMC96047.1 - 5e-50 169.7 0.1 1.2e-46 158.7 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Ank_2 PF12796.2 EMC96048.1 - 5.6e-24 84.2 0.6 8e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC96048.1 - 1.1e-20 73.1 4.2 2.4e-10 40.3 0.4 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC96048.1 - 5.8e-19 66.8 7.7 7.3e-09 35.0 0.4 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EMC96048.1 - 1.1e-16 59.1 0.7 5.7e-05 22.9 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMC96048.1 - 1.2e-14 54.3 1.2 3.2e-06 27.4 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) UQ_con PF00179.21 EMC96049.1 - 2.2e-51 173.0 0.0 2.4e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC96049.1 - 6.9e-05 22.6 0.0 8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC96049.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC96049.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.20 EMC96050.1 - 1.4e-39 135.8 0.9 3.8e-18 65.5 0.0 4.2 2 1 2 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 EMC96050.1 - 3.4e-19 68.9 0.1 1.5e-06 27.4 0.0 4.0 3 1 1 4 4 4 3 Protein tyrosine kinase APH PF01636.18 EMC96050.1 - 0.031 14.0 0.1 0.091 12.4 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family KAR9 PF08580.5 EMC96051.1 - 4.4e-102 342.5 0.4 4.4e-102 342.5 0.3 1.6 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Kelch_5 PF13854.1 EMC96052.1 - 3.3e-15 55.6 5.6 1.8e-10 40.5 0.1 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EMC96052.1 - 3.7e-08 33.0 21.5 0.001 18.7 0.6 5.9 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EMC96052.1 - 6.8e-05 22.8 17.1 0.091 12.9 0.4 5.1 4 1 1 5 5 5 2 Kelch motif SKG6 PF08693.5 EMC96052.1 - 9.4e-05 21.6 0.6 9.4e-05 21.6 0.4 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Kelch_1 PF01344.20 EMC96052.1 - 0.00086 18.7 12.2 0.014 14.9 0.7 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EMC96052.1 - 0.026 14.2 8.4 0.042 13.6 0.4 4.5 3 1 0 3 3 3 0 Kelch motif YajC PF02699.10 EMC96052.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Adeno_E3_CR2 PF02439.10 EMC96052.1 - 1.5 8.4 7.7 2.8 7.5 5.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Fringe PF02434.11 EMC96054.1 - 0.0031 16.7 0.3 0.035 13.3 0.2 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EMC96054.1 - 0.0044 16.6 3.1 0.012 15.2 2.2 1.7 1 0 0 1 1 1 1 PAN domain PGM_PMM_I PF02878.11 EMC96055.1 - 5.7e-39 132.7 0.0 9.5e-39 132.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMC96055.1 - 9.4e-20 70.8 0.0 2.2e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EMC96055.1 - 6.3e-12 45.5 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EMC96055.1 - 1.2e-08 34.8 0.0 3.6e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BTB PF00651.26 EMC96055.1 - 0.13 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Sec23_trunk PF04811.10 EMC96056.1 - 4.2e-49 167.1 0.0 1.6e-48 165.2 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMC96056.1 - 3.1e-24 84.3 0.0 5.3e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EMC96056.1 - 2.6e-18 65.3 5.4 5.1e-18 64.3 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EMC96056.1 - 3.7e-17 62.6 0.3 7.5e-17 61.6 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EMC96056.1 - 8.6e-08 31.7 0.0 1.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Aa_trans PF01490.13 EMC96057.1 - 1.7e-28 99.2 31.4 2.2e-28 98.8 21.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.19 EMC96058.1 - 1.1e-76 258.2 20.8 1.4e-76 257.9 14.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96058.1 - 3.5e-15 55.5 52.1 1.3e-08 33.9 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flocculin_t3 PF13928.1 EMC96061.1 - 0.05 13.7 7.1 0.05 13.7 4.9 2.6 1 1 1 2 2 2 0 Flocculin type 3 repeat PrpF PF04303.8 EMC96062.1 - 2.9e-104 348.7 0.4 3.3e-104 348.5 0.3 1.0 1 0 0 1 1 1 1 PrpF protein CinA PF02464.12 EMC96063.1 - 3.2e-32 111.1 0.1 3.7e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein ThiF PF00899.16 EMC96064.1 - 2.2e-28 98.7 0.0 3.5e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EMC96064.1 - 0.048 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_S15 PF02129.13 EMC96066.1 - 7.5e-26 91.1 3.1 8.2e-19 68.0 0.0 3.0 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMC96066.1 - 1.6e-23 83.7 0.0 2.5e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain FAD_binding_3 PF01494.14 EMC96067.1 - 2e-67 227.7 0.3 8.7e-67 225.6 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMC96067.1 - 1.6e-05 25.1 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMC96067.1 - 0.0012 18.8 0.3 0.0082 16.1 0.0 2.4 3 0 0 3 3 3 1 TrkA-N domain Pyr_redox_3 PF13738.1 EMC96067.1 - 0.0013 18.7 0.0 0.0042 17.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 EMC96067.1 - 0.0015 18.8 0.0 0.0055 17.0 0.0 2.0 2 0 0 2 2 1 1 XdhC Rossmann domain NAD_binding_8 PF13450.1 EMC96067.1 - 0.0044 17.0 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC96067.1 - 0.0073 16.2 0.0 0.036 13.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC96067.1 - 0.0079 15.3 0.1 0.026 13.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EMC96067.1 - 0.0096 14.8 0.1 0.16 10.8 0.0 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 EMC96067.1 - 0.031 14.2 0.3 0.17 11.9 0.0 2.4 4 0 0 4 4 3 0 NADH(P)-binding ApbA PF02558.11 EMC96067.1 - 0.071 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EMC96067.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EMC96067.1 - 0.13 11.1 0.4 0.31 9.9 0.0 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein Lactamase_B_3 PF13483.1 EMC96068.1 - 4.9e-11 42.5 0.0 1.3e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC96068.1 - 1.7e-07 31.0 0.2 2.9e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC96068.1 - 4.5e-05 23.0 0.1 6.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TRI12 PF06609.8 EMC96069.1 - 8.9e-26 90.2 22.2 1.2e-25 89.8 15.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMC96069.1 - 4.3e-23 81.6 53.3 4.4e-20 71.6 34.7 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC96069.1 - 2e-05 23.3 15.4 2e-05 23.3 10.7 3.8 3 1 0 3 3 3 2 Sugar (and other) transporter DUF4229 PF14012.1 EMC96069.1 - 0.093 12.6 0.3 0.093 12.6 0.2 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF4229) adh_short PF00106.20 EMC96070.1 - 5e-25 88.3 0.0 6.4e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC96070.1 - 1.4e-11 44.5 0.0 2.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC96070.1 - 3.1e-09 36.7 0.0 4.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EMC96070.1 - 0.00029 21.2 0.4 0.00057 20.2 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EMC96070.1 - 0.016 14.8 0.2 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMC96070.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 EMC96070.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 EMC96071.1 - 6.1e-10 38.3 0.1 1.7e-09 36.9 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain 6PGD PF00393.14 EMC96072.1 - 5.7e-133 442.5 0.0 7.4e-133 442.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EMC96072.1 - 1.4e-49 168.0 0.1 2.1e-49 167.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMC96072.1 - 0.063 13.3 0.4 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.17 EMC96073.1 - 5.6e-14 51.5 0.0 6.9e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC96073.1 - 2.7e-08 33.6 0.0 3.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GST_C PF00043.20 EMC96075.1 - 5.5e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC96075.1 - 3.5e-10 39.9 0.0 6.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC96075.1 - 2.6e-09 37.1 0.2 2.2e-08 34.1 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC96075.1 - 5.4e-09 35.9 0.0 9.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC96075.1 - 7.5e-08 32.7 0.1 1.4e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC96075.1 - 4.2e-06 26.5 0.0 6.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCCH_2 PF14608.1 EMC96076.1 - 2.9e-09 36.5 54.0 0.00033 20.5 7.1 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type WD40 PF00400.27 EMC96077.1 - 6.6e-07 28.9 0.1 1.4 8.9 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF2583 PF10762.4 EMC96077.1 - 0.37 10.9 1.4 0.65 10.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Mago-bind PF09282.5 EMC96078.1 - 3.8e-13 48.7 2.7 7.4e-13 47.8 1.9 1.5 1 0 0 1 1 1 1 Mago binding DASH_Spc34 PF08657.5 EMC96078.1 - 0.021 14.4 0.1 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 PAPS_reduct PF01507.14 EMC96078.1 - 0.13 12.0 0.3 0.26 11.0 0.2 1.5 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family UCR_UQCRX_QCR9 PF05365.7 EMC96079.1 - 1.8e-24 85.1 0.8 2e-24 84.9 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 EMC96080.1 - 4.2e-18 64.8 15.2 4.2e-18 64.8 10.5 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EMC96080.1 - 4.4e-07 29.5 0.2 4.7e-06 26.2 0.1 2.4 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EMC96080.1 - 0.0014 18.4 3.2 0.0014 18.4 2.2 4.2 4 1 0 4 4 4 1 Ring finger domain YndJ PF14158.1 EMC96082.1 - 0.047 12.7 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 YndJ-like protein FmdA_AmdA PF03069.10 EMC96083.1 - 2.3e-153 510.2 0.1 2.6e-153 510.1 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Mg_trans_NIPA PF05653.9 EMC96084.1 - 5.4e-90 301.3 24.6 7.8e-90 300.8 17.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMC96084.1 - 4.1e-07 30.1 1.4 4.1e-07 30.1 0.9 3.5 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC96084.1 - 6.2e-07 29.5 4.8 6.2e-07 29.5 3.3 3.2 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 EMC96084.1 - 1.6 7.5 16.2 2.6 6.8 11.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) COG4 PF08318.7 EMC96085.1 - 1.1e-99 333.3 0.0 1.5e-99 332.9 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein HATPase_c PF02518.21 EMC96086.1 - 1.3e-24 85.9 0.3 2.5e-24 85.1 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMC96086.1 - 8e-20 70.6 0.4 4e-19 68.3 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EMC96086.1 - 2.5e-19 69.1 1.6 1.4e-10 41.1 0.2 3.7 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.19 EMC96086.1 - 2.8e-17 62.7 0.1 8.4e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 EMC96086.1 - 1.5e-16 60.6 0.0 4.5e-11 43.0 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS PF00989.19 EMC96086.1 - 2.2e-13 49.9 0.0 5.7e-07 29.3 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EMC96086.1 - 3.4e-13 49.5 3.0 8.9e-10 38.5 0.0 4.5 5 0 0 5 5 5 2 PAS fold Cutinase PF01083.17 EMC96088.1 - 5.1e-38 130.5 1.9 5.9e-38 130.3 1.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMC96088.1 - 0.029 13.7 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 PE-PPE domain AOX PF01786.12 EMC96090.1 - 7.2e-90 299.9 0.4 9.6e-90 299.5 0.3 1.2 1 0 0 1 1 1 1 Alternative oxidase Acylphosphatase PF00708.13 EMC96090.1 - 1.9e-24 85.5 0.3 3.6e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 Acylphosphatase Sulphotransf PF09037.5 EMC96090.1 - 0.058 12.8 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Stf0 sulphotransferase RNase_HII PF01351.13 EMC96090.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease HII Pkinase PF00069.20 EMC96091.1 - 1.5e-11 43.9 0.0 2.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC96091.1 - 5.3e-09 35.5 0.0 7.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC96091.1 - 0.0079 15.2 0.0 0.015 14.4 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC96091.1 - 0.038 12.9 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like p450 PF00067.17 EMC96093.1 - 2.1e-56 191.3 0.0 2.6e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 EMC96094.1 - 1.1e-76 252.6 2.7 3.4e-25 87.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MIP-T3 PF10243.4 EMC96095.1 - 5 5.4 34.6 7.1 4.9 24.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ELFV_dehydrog PF00208.16 EMC96096.1 - 4.2e-60 203.3 0.0 9.1e-60 202.2 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EMC96096.1 - 9.3e-17 59.8 0.1 2.3e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EMC96096.1 - 0.0085 15.6 0.0 0.028 13.9 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CorA PF01544.13 EMC96098.1 - 2.7e-44 151.3 0.5 2.6e-21 75.9 0.3 2.5 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Hamartin PF04388.7 EMC96098.1 - 0.25 9.9 5.1 0.41 9.2 3.5 1.3 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.20 EMC96099.1 - 1.8e-43 148.6 0.0 2.2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC96099.1 - 2.8e-16 59.3 0.0 4.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC96099.1 - 9.9e-05 21.4 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC96099.1 - 0.0013 18.5 0.1 0.023 14.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC96099.1 - 0.0069 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AdoMet_Synthase PF01941.14 EMC96100.1 - 0.03 12.8 0.2 0.052 12.0 0.1 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Acyltransferase PF01553.16 EMC96101.1 - 5.8e-26 90.4 0.0 1e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF1330 PF07045.6 EMC96102.1 - 0.15 11.9 0.3 0.29 11.0 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1330) Hep_59 PF07052.6 EMC96103.1 - 0.00034 20.9 0.5 0.00084 19.6 0.4 1.7 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Elongin_A PF06881.6 EMC96104.1 - 2.9e-22 79.0 0.1 6.4e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TBCA PF02970.11 EMC96105.1 - 8.8e-23 80.1 5.6 1.1e-22 79.8 3.9 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF2570 PF10828.3 EMC96105.1 - 0.0076 15.8 2.5 0.011 15.2 1.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2570) Exonuc_VII_L PF02601.10 EMC96105.1 - 0.043 13.0 2.8 0.047 12.8 2.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 EMC96105.1 - 0.054 11.9 3.5 0.06 11.7 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4398 PF14346.1 EMC96105.1 - 0.071 13.1 0.5 0.071 13.1 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) DUF4404 PF14357.1 EMC96105.1 - 0.22 11.9 4.0 0.16 12.4 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) HAUS6_N PF14661.1 EMC96105.1 - 0.29 10.4 3.6 0.33 10.2 2.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spectrin PF00435.16 EMC96105.1 - 0.64 10.3 7.1 0.66 10.2 3.7 1.8 1 1 1 2 2 2 0 Spectrin repeat V_ATPase_I PF01496.14 EMC96105.1 - 0.67 7.7 2.7 0.69 7.6 1.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 EMC96105.1 - 0.82 8.8 6.6 0.72 9.0 3.9 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.7 EMC96105.1 - 1.3 8.3 11.7 60 2.8 8.1 2.5 1 1 0 1 1 1 0 PspA/IM30 family DUF4407 PF14362.1 EMC96105.1 - 1.3 7.8 6.7 1.8 7.4 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-Q PF13094.1 EMC96105.1 - 1.4 8.9 10.3 2.4 8.1 1.7 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4315 PF14193.1 EMC96105.1 - 1.9 8.4 10.2 9.9 6.1 0.1 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4315) Mnd1 PF03962.10 EMC96105.1 - 2.6 7.6 7.9 4.3 6.9 5.4 1.4 1 1 0 1 1 1 0 Mnd1 family TPR_MLP1_2 PF07926.7 EMC96105.1 - 3.2 7.4 8.9 3 7.5 3.9 2.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlgN PF05130.7 EMC96105.1 - 4.5 7.5 8.6 2.6 8.2 3.9 1.8 1 1 1 2 2 2 0 FlgN protein MCM PF00493.18 EMC96106.1 - 1.6e-136 454.4 0.0 2.2e-136 454.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMC96106.1 - 1.2e-20 74.1 0.0 3.9e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMC96106.1 - 1.2e-05 24.6 0.0 0.00029 20.0 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMC96106.1 - 6.3e-05 22.7 0.0 0.00025 20.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMC96106.1 - 0.0018 17.8 0.0 0.0056 16.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EMC96106.1 - 0.0066 15.1 0.7 0.012 14.3 0.5 1.3 1 0 0 1 1 1 1 AAA domain PemK PF02452.12 EMC96106.1 - 0.09 12.9 0.1 0.31 11.2 0.1 1.9 1 0 0 1 1 1 0 PemK-like protein Sigma54_activat PF00158.21 EMC96106.1 - 0.11 12.0 0.1 4.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain ubiquitin PF00240.18 EMC96107.1 - 6e-25 86.4 0.0 6.7e-25 86.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMC96107.1 - 7.8e-16 57.5 0.1 8.6e-16 57.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC96107.1 - 0.00059 20.0 0.1 0.0015 18.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMC96107.1 - 0.058 13.2 0.1 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like AD PF09793.4 EMC96108.1 - 3e-18 65.4 0.3 7e-18 64.2 0.2 1.6 1 1 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.7 EMC96108.1 - 0.023 14.0 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 0 Gemin6 protein Melibiase PF02065.13 EMC96109.1 - 5.2e-08 31.9 0.1 4.4e-06 25.6 0.0 2.6 2 1 0 2 2 2 2 Melibiase Sgf11 PF08209.6 EMC96112.1 - 0.12 11.7 0.7 0.17 11.2 0.1 1.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Herpes_UL36 PF03586.8 EMC96114.1 - 0.097 11.7 0.0 0.3 10.1 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Ank PF00023.25 EMC96115.1 - 1.2e-07 31.2 1.8 0.58 10.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EMC96115.1 - 2e-07 31.2 0.1 0.084 13.2 0.0 3.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) TPR_12 PF13424.1 EMC96115.1 - 3e-07 30.2 0.5 0.00053 19.8 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_5 PF13857.1 EMC96115.1 - 6.4e-06 26.2 0.9 0.19 12.0 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) TPR_11 PF13414.1 EMC96115.1 - 4.3e-05 23.0 2.1 0.0023 17.5 0.3 3.1 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 EMC96115.1 - 0.00029 21.1 0.2 1.2 9.5 0.0 3.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Ank_3 PF13606.1 EMC96115.1 - 0.0035 17.4 1.8 4.7 7.7 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat TPR_2 PF07719.12 EMC96115.1 - 0.0066 16.2 1.0 10 6.3 0.6 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC96115.1 - 0.0086 15.7 0.3 6.6 6.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF948 PF06103.6 EMC96115.1 - 0.017 14.9 0.2 34 4.4 0.0 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TrbE PF11100.3 EMC96119.1 - 0.037 13.8 0.5 0.058 13.2 0.4 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbE DUF3671 PF12420.3 EMC96119.1 - 0.27 11.2 2.2 0.34 10.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2477 PF10631.4 EMC96119.1 - 1.1 9.4 5.3 1.5 9.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) DivIC PF04977.10 EMC96121.1 - 0.0069 15.8 4.1 0.012 15.1 2.8 1.3 1 0 0 1 1 1 1 Septum formation initiator DUF4140 PF13600.1 EMC96121.1 - 0.025 15.0 1.1 0.055 13.9 0.7 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HlyD PF00529.15 EMC96121.1 - 0.03 13.6 2.7 0.041 13.1 1.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein IncA PF04156.9 EMC96121.1 - 0.033 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 IncA protein Uds1 PF15456.1 EMC96121.1 - 0.057 13.4 1.9 0.14 12.1 1.3 1.6 1 0 0 1 1 1 0 Up-regulated During Septation FemAB PF02388.11 EMC96121.1 - 0.094 11.3 0.7 0.14 10.8 0.5 1.2 1 0 0 1 1 1 0 FemAB family CENP-Q PF13094.1 EMC96121.1 - 0.1 12.6 4.0 0.22 11.5 2.8 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ax_dynein_light PF10211.4 EMC96121.1 - 0.18 11.6 3.8 0.36 10.6 2.6 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain SIP PF04954.8 EMC96121.1 - 4 7.8 7.1 14 6.0 4.9 1.8 1 1 0 1 1 1 0 Siderophore-interacting protein Epimerase PF01370.16 EMC96128.1 - 3.7e-26 92.0 0.0 5.6e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC96128.1 - 2.8e-13 49.3 0.0 4.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMC96128.1 - 1.8e-11 43.4 0.0 8.1e-10 38.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EMC96128.1 - 7.5e-09 35.8 0.0 7.4e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMC96128.1 - 1.9e-08 33.3 0.0 8.2e-08 31.2 0.0 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMC96128.1 - 1.4e-07 30.7 0.0 7.3e-05 21.7 0.0 2.7 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.8 EMC96128.1 - 0.034 13.3 0.1 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.20 EMC96128.1 - 0.14 12.0 0.1 1 9.2 0.0 2.3 1 1 0 1 1 1 0 short chain dehydrogenase TauD PF02668.11 EMC96131.1 - 5.5e-44 150.7 0.0 7e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EMC96132.1 - 2.9e-23 82.1 19.2 3.8e-23 81.7 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMC96132.1 - 0.00037 20.0 1.4 0.00037 20.0 0.9 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.2 EMC96132.1 - 0.0085 15.8 1.8 0.016 14.9 0.3 2.3 2 0 0 2 2 2 1 MFS_1 like family Alpha-amyl_C2 PF07821.7 EMC96132.1 - 0.059 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain HAD_2 PF13419.1 EMC96133.1 - 3.7e-20 72.8 0.0 6.7e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.1 EMC96134.1 - 0.0052 16.5 0.0 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EMC96134.1 - 0.023 14.0 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.2 EMC96134.1 - 0.085 13.4 0.2 0.14 12.7 0.1 1.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 EMC96134.1 - 0.1 11.2 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Proteasome PF00227.21 EMC96135.1 - 5.7e-54 182.3 0.1 7.9e-54 181.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC96135.1 - 1.2e-13 50.1 0.0 2.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EMC96135.1 - 0.069 12.8 0.0 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Spc97_Spc98 PF04130.8 EMC96136.1 - 8.4e-136 453.4 0.0 1e-135 453.1 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family APG6 PF04111.7 EMC96137.1 - 0.0032 16.5 18.0 0.0044 16.1 12.5 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 ERM PF00769.14 EMC96137.1 - 0.021 14.3 30.3 0.088 12.3 13.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Borrelia_P83 PF05262.6 EMC96137.1 - 0.059 11.6 16.3 0.071 11.3 11.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ADIP PF11559.3 EMC96137.1 - 0.13 12.1 25.5 0.44 10.4 2.4 2.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF874 PF05917.6 EMC96137.1 - 1.4 7.7 16.4 1.8 7.2 11.3 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) zf-C4H2 PF10146.4 EMC96137.1 - 1.4 8.8 12.7 0.34 10.9 2.5 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein V_ATPase_I PF01496.14 EMC96137.1 - 2.3 5.9 10.2 3 5.5 7.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 EMC96137.1 - 2.8 6.5 16.1 4.4 5.8 11.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_2 PF07716.10 EMC96137.1 - 2.9 7.7 17.0 0.058 13.2 5.6 2.4 1 1 2 3 3 2 0 Basic region leucine zipper Bacillus_HBL PF05791.6 EMC96137.1 - 3.1 7.1 12.9 0.7 9.2 3.0 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HlyD PF00529.15 EMC96137.1 - 5.7 6.1 28.8 1.9 7.7 17.5 1.7 1 1 1 2 2 2 0 HlyD family secretion protein BTV_NS2 PF04514.7 EMC96137.1 - 8 5.2 15.0 12 4.6 10.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2968 PF11180.3 EMC96137.1 - 8.3 5.7 34.4 0.42 9.9 16.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4472 PF14739.1 EMC96137.1 - 8.5 6.8 18.5 18 5.8 7.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Zn_clus PF00172.13 EMC96138.1 - 0.013 15.3 15.6 0.013 15.3 10.8 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FtsL PF04999.8 EMC96138.1 - 0.36 10.5 4.4 0.44 10.3 0.9 2.4 2 0 0 2 2 2 0 Cell division protein FtsL Spheroidin PF05541.7 EMC96138.1 - 5.2 4.5 4.7 7.3 4.0 3.3 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein Seryl_tRNA_N PF02403.17 EMC96138.1 - 6.7 6.7 9.9 0.48 10.4 2.3 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3432 PF11914.3 EMC96138.1 - 9.4 6.3 18.5 0.18 11.8 7.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) DUF3481 PF11980.3 EMC96139.1 - 0.042 13.6 1.3 0.054 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Amidase PF01425.16 EMC96140.1 - 8.3e-94 314.9 0.1 1e-93 314.6 0.1 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.16 EMC96141.1 - 2.2e-07 30.5 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase COX4 PF02936.9 EMC96142.1 - 5.6e-17 61.8 0.5 8.1e-17 61.2 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 EMC96142.1 - 0.023 15.0 0.7 0.037 14.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF3112 PF11309.3 EMC96143.1 - 1.5e-36 125.6 19.2 1e-35 122.8 5.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) LRR19-TM PF15176.1 EMC96143.1 - 0.54 9.9 0.0 0.54 9.9 0.0 2.8 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Zn_clus PF00172.13 EMC96144.1 - 0.00027 20.7 9.4 0.00047 19.9 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 EMC96147.1 - 2.6e-37 128.8 0.2 3.3e-37 128.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_6 PF12697.2 EMC96148.1 - 2.6e-33 115.8 0.4 3.1e-33 115.5 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC96148.1 - 3.2e-20 72.3 0.0 1.6e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC96148.1 - 2.9e-10 40.0 0.1 6.4e-09 35.7 0.1 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMC96148.1 - 2.7e-07 30.3 0.0 5.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EMC96148.1 - 6.9e-07 29.7 0.0 3.3e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain FSH1 PF03959.8 EMC96148.1 - 4.2e-05 23.0 0.0 0.00051 19.5 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Ser_hydrolase PF06821.8 EMC96148.1 - 4.6e-05 23.0 0.1 0.11 12.1 0.4 2.5 1 1 1 2 2 2 2 Serine hydrolase PGAP1 PF07819.8 EMC96148.1 - 9.1e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 EMC96148.1 - 0.0015 17.9 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 EMC96148.1 - 0.0048 16.7 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.15 EMC96148.1 - 0.007 15.8 0.1 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.9 EMC96148.1 - 0.011 14.2 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydro_lipase PF04083.11 EMC96148.1 - 0.016 14.5 0.1 0.18 11.1 0.0 2.2 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_3 PF07859.8 EMC96148.1 - 0.035 13.6 0.2 0.93 9.0 0.1 2.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1057 PF06342.7 EMC96148.1 - 0.038 12.8 0.1 0.11 11.3 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF1749 PF08538.5 EMC96148.1 - 0.04 12.8 0.1 0.067 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2305 PF10230.4 EMC96148.1 - 0.077 12.3 0.0 0.24 10.7 0.0 1.8 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2305) Transp_cyt_pur PF02133.10 EMC96150.1 - 7.6e-83 278.4 36.7 1e-82 278.0 25.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 EMC96151.1 - 1.6e-30 105.9 0.0 3.2e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMC96151.1 - 2.7e-22 78.9 0.1 5e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HOOK PF05622.7 EMC96153.1 - 3.2e-14 51.7 40.4 2.3e-12 45.5 0.0 3.1 1 1 2 3 3 3 2 HOOK protein DUF2937 PF11157.3 EMC96153.1 - 0.011 15.0 5.5 0.011 15.0 3.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) Occludin_ELL PF07303.8 EMC96153.1 - 0.018 15.7 6.9 0.018 15.7 4.8 3.8 3 1 1 4 4 4 0 Occludin homology domain FlaC_arch PF05377.6 EMC96153.1 - 0.21 11.5 7.3 24 4.9 0.0 4.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EMC96153.1 - 0.21 11.1 47.0 0.32 10.5 4.4 3.2 2 1 1 3 3 3 0 IncA protein GAS PF13851.1 EMC96153.1 - 0.57 9.3 37.1 0.31 10.1 1.0 3.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EMC96153.1 - 3.4 7.5 38.1 0.46 10.3 1.4 5.3 2 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 EMC96153.1 - 4 7.5 22.5 26 4.9 0.1 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 EMC96153.1 - 6.9 6.4 43.7 0.075 12.7 12.0 3.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EMC96153.1 - 9 6.0 38.5 1 9.1 3.0 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) HOOK PF05622.7 EMC96154.1 - 0.04 11.7 0.1 0.042 11.6 0.0 1.0 1 0 0 1 1 1 0 HOOK protein Mito_carr PF00153.22 EMC96155.1 - 1e-52 175.8 2.0 2e-17 62.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Abp2 PF09441.5 EMC96156.1 - 1.8e-80 268.9 0.0 3e-80 268.2 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TPT PF03151.11 EMC96158.1 - 1.9e-38 131.5 0.6 1.9e-38 131.5 0.4 2.4 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EMC96158.1 - 5.7e-13 48.4 4.7 1e-12 47.6 3.2 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMC96158.1 - 4.6e-07 29.9 23.7 3.1e-05 23.9 3.4 3.1 2 1 0 2 2 2 2 EamA-like transporter family Peptidase_S9 PF00326.16 EMC96159.1 - 4.8e-09 35.7 0.2 7.4e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC96159.1 - 5.5e-07 29.4 0.1 1e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMC96159.1 - 0.0014 18.1 0.3 0.003 17.0 0.2 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EMC96159.1 - 0.024 14.0 0.1 0.079 12.3 0.0 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF4399 PF14347.1 EMC96159.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) RHD3 PF05879.7 EMC96160.1 - 0 1032.5 0.0 0 1032.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EMC96160.1 - 5.4e-08 32.1 0.0 8.1e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EMC96160.1 - 5.5e-06 26.2 0.4 1.1e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EMC96160.1 - 0.00034 20.5 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC96160.1 - 0.0049 17.3 0.1 0.0099 16.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EMC96160.1 - 0.026 14.4 0.1 0.096 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EMC96160.1 - 0.066 12.2 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1798 PF08807.5 EMC96160.1 - 0.08 12.6 0.3 0.2 11.3 0.2 1.7 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Phosphodiest PF01663.17 EMC96161.1 - 1.5e-12 47.5 0.3 2.6e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMC96161.1 - 4e-05 22.9 0.0 6.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EMC96161.1 - 0.00027 20.4 0.1 0.00044 19.7 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Gly-zipper_OmpA PF13436.1 EMC96161.1 - 2.9 7.5 4.4 6.8 6.3 3.0 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Cohesin_load PF10345.4 EMC96162.1 - 1.5e-106 357.0 3.3 1.8e-106 356.8 2.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_7 PF13176.1 EMC96163.1 - 0.21 11.4 1.8 2.4 8.1 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MLP1_2 PF07926.7 EMC96163.1 - 0.84 9.3 17.1 2.4 7.9 11.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EMC96163.1 - 3.2 5.5 7.2 4.5 5.0 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EMC96163.1 - 7.8 5.4 15.4 13 4.6 10.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 EMC96163.1 - 9.4 5.7 15.5 0.094 12.2 4.1 2.4 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vps55 PF04133.9 EMC96164.1 - 2.3e-44 149.9 4.7 2.6e-44 149.8 3.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.21 EMC96165.1 - 6.9e-43 146.1 0.0 9.1e-43 145.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC96165.1 - 7.2e-12 44.3 0.3 1.3e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATP-synt_ab PF00006.20 EMC96166.1 - 1.4e-61 207.7 0.0 2.1e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMC96166.1 - 6e-26 91.1 1.2 1.1e-25 90.2 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMC96166.1 - 1e-23 83.3 1.2 5e-23 81.1 0.7 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain MobB PF03205.9 EMC96166.1 - 0.0052 16.4 0.3 2.1 8.0 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EMC96166.1 - 0.011 14.8 0.2 0.02 14.0 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.24 EMC96166.1 - 0.015 15.4 0.0 0.84 9.8 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMC96166.1 - 0.017 14.5 0.1 0.053 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMC96166.1 - 0.019 14.1 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EMC96166.1 - 0.024 14.2 0.3 0.079 12.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EMC96166.1 - 0.071 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EMC96166.1 - 0.095 12.6 0.4 0.31 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EMC96166.1 - 0.11 12.6 0.0 0.36 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMC96166.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EMC96166.1 - 0.17 10.7 1.8 0.58 8.9 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain Aminotran_3 PF00202.16 EMC96167.1 - 2.8e-99 332.1 0.0 3.3e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMC96167.1 - 0.041 12.8 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3402 PF11882.3 EMC96168.1 - 2.3e-119 399.1 0.0 3.4e-119 398.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EMC96168.1 - 2.9e-77 259.4 0.0 4.5e-77 258.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Abhydrolase_6 PF12697.2 EMC96169.1 - 6.5e-10 39.2 0.2 1e-09 38.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC96169.1 - 1.1e-06 28.3 0.0 2.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.6 EMC96169.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cutinase PF01083.17 EMC96169.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Psb28 PF03912.9 EMC96170.1 - 0.018 14.9 0.3 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 Psb28 protein GYD PF08734.6 EMC96170.1 - 0.043 13.5 0.3 0.088 12.5 0.2 1.5 1 0 0 1 1 1 0 GYD domain DUF4376 PF14301.1 EMC96170.1 - 0.043 13.9 6.8 0.06 13.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) D123 PF07065.9 EMC96171.1 - 4.5e-93 311.5 0.0 3e-92 308.8 0.0 1.9 1 1 0 1 1 1 1 D123 NAD_binding_10 PF13460.1 EMC96172.1 - 6.8e-11 42.4 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC96172.1 - 2.2e-06 27.1 0.0 3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMC96172.1 - 0.00074 19.0 0.0 0.0043 16.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMC96172.1 - 0.0029 17.5 0.3 0.0074 16.2 0.1 1.8 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMC96172.1 - 0.042 13.5 0.5 0.097 12.3 0.0 1.9 2 1 0 2 2 2 0 KR domain Saccharop_dh PF03435.13 EMC96172.1 - 0.058 12.3 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EMC96172.1 - 0.11 12.5 0.0 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF2202 PF09968.4 EMC96172.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Polysacc_deac_1 PF01522.16 EMC96174.1 - 8.8e-16 57.6 0.3 1.2e-14 53.9 0.2 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase 6PF2K PF01591.13 EMC96175.1 - 6.1e-75 251.1 0.0 8.6e-75 250.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMC96175.1 - 1.9e-24 86.5 0.0 5.8e-24 84.9 0.0 1.9 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMC96175.1 - 5.8e-09 35.9 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC96175.1 - 1e-05 24.7 0.0 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EMC96175.1 - 0.00015 22.6 0.0 0.0004 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMC96175.1 - 0.0079 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 FliT PF05400.8 EMC96179.1 - 0.052 13.9 0.2 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 Flagellar protein FliT Acyl-CoA_dh_1 PF00441.19 EMC96181.1 - 1.7e-38 132.0 0.9 2.6e-38 131.4 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC96181.1 - 2e-16 59.2 0.1 4e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC96181.1 - 2.1e-15 57.1 0.1 3.6e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC96181.1 - 2.7e-08 34.3 0.9 1.7e-07 31.7 0.1 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Mst1_SARAH PF11629.3 EMC96181.1 - 0.23 11.2 1.1 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 EthD PF07110.6 EMC96183.1 - 1.9e-20 73.6 0.2 2.3e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 EthD domain DUF947 PF06102.7 EMC96184.1 - 8.1e-47 159.1 22.7 8.1e-47 159.1 15.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF947) MIT PF04212.13 EMC96184.1 - 0.52 10.2 5.6 0.66 9.8 0.1 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF4404 PF14357.1 EMC96184.1 - 2.1 8.8 12.3 9 6.7 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) T4SS PF07996.6 EMC96184.1 - 8.7 6.1 9.9 29 4.4 6.2 2.1 1 1 0 1 1 1 0 Type IV secretion system proteins HIG_1_N PF04588.8 EMC96185.1 - 2.7e-06 27.0 2.1 2.7e-06 27.0 1.5 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region CAF-1_p150 PF11600.3 EMC96185.1 - 0.94 8.8 17.2 0.3 10.4 9.1 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1910 PF08928.5 EMC96185.1 - 2.3 8.2 5.0 2 8.4 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Serglycin PF04360.7 EMC96186.1 - 0.18 11.5 3.7 0.14 11.8 1.0 1.9 2 0 0 2 2 2 0 Serglycin Vps51 PF08700.6 EMC96187.1 - 1.5e-11 43.9 0.0 1.5e-10 40.7 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EMC96187.1 - 0.031 14.1 5.3 1.4 8.7 0.1 4.3 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.8 EMC96187.1 - 0.099 10.7 0.4 2.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Apolipoprotein PF01442.13 EMC96187.1 - 3.3 7.1 8.3 6.5 6.2 2.3 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Methyltransf_26 PF13659.1 EMC96188.1 - 3.1e-12 46.5 0.0 6.4e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC96188.1 - 1.3e-07 31.3 0.0 7.9e-07 28.7 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC96188.1 - 2e-07 31.5 0.0 7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC96188.1 - 8e-06 26.1 0.0 3.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 EMC96188.1 - 0.00027 20.1 0.0 0.0013 17.9 0.0 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.7 EMC96188.1 - 0.00045 19.4 0.0 0.0026 16.9 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF890) MTS PF05175.9 EMC96188.1 - 0.0064 15.8 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 EMC96188.1 - 0.02 14.4 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 XPC-binding PF09280.6 EMC96189.1 - 6.9e-24 83.0 15.4 1.3e-23 82.1 10.6 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EMC96189.1 - 2.1e-19 68.6 0.4 3.1e-19 68.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMC96189.1 - 6.2e-17 60.8 3.1 1.3e-08 34.4 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EMC96189.1 - 1.8e-09 37.1 0.2 3.4e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EMC96189.1 - 0.0028 18.1 0.1 0.0052 17.2 0.1 1.4 1 0 0 1 1 1 1 MCM N-terminal domain DUF2407 PF10302.4 EMC96189.1 - 0.0032 17.6 0.0 0.0074 16.4 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EMC96189.1 - 0.0068 16.6 0.1 0.017 15.3 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMC96189.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EMC96189.1 - 0.037 13.6 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF3135 PF11333.3 EMC96189.1 - 0.078 13.1 4.7 0.79 9.9 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) TMEM51 PF15345.1 EMC96192.1 - 0.0013 18.5 0.2 0.0015 18.2 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Sarcoglycan_2 PF05510.8 EMC96192.1 - 0.009 14.3 0.2 0.011 14.0 0.1 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon SIT PF15330.1 EMC96192.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT SOBP PF15279.1 EMC96192.1 - 0.049 14.0 0.1 0.054 13.8 0.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3609 PF12259.3 EMC96192.1 - 0.06 11.9 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Herpes_gE PF02480.11 EMC96192.1 - 0.067 11.4 0.5 0.076 11.2 0.3 1.2 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EMC96192.1 - 0.071 12.8 0.4 0.11 12.1 0.2 1.3 1 1 0 1 1 1 0 TMEM154 protein family SMP_2 PF10144.4 EMC96192.1 - 0.075 12.1 0.4 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin HemY_N PF07219.8 EMC96192.1 - 0.096 12.2 0.9 0.17 11.4 0.6 1.3 1 0 0 1 1 1 0 HemY protein N-terminus CD34_antigen PF06365.7 EMC96192.1 - 0.14 11.8 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.1 EMC96192.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EMC96192.1 - 0.15 11.6 0.1 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family RCR PF12273.3 EMC96192.1 - 0.85 10.1 3.5 0.58 10.7 0.4 2.1 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Myb_DNA-binding PF00249.26 EMC96193.1 - 3e-14 52.8 2.6 6.6e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC96193.1 - 5.6e-09 35.9 8.5 2.1e-06 27.7 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.20 EMC96195.1 - 5.9e-26 89.9 0.2 8.3e-26 89.4 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EMC96195.1 - 6e-20 71.2 0.0 8.7e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EMC96195.1 - 0.00022 20.5 0.0 0.00042 19.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Gemini_AL2 PF01440.11 EMC96195.1 - 0.19 11.8 2.2 0.94 9.5 0.1 2.2 2 0 0 2 2 2 0 Geminivirus AL2 protein CENP-C_C PF11699.3 EMC96196.1 - 3.8e-25 87.6 0.2 6.3e-25 86.9 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EMC96196.1 - 1.3e-23 84.0 0.2 1.3e-23 84.0 0.1 4.1 3 1 2 5 5 5 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EMC96196.1 - 0.0094 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF2561 PF10812.3 EMC96197.1 - 0.042 13.4 0.1 0.056 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) HXXEE PF13787.1 EMC96197.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif RNase_HII PF01351.13 EMC96198.1 - 2e-46 158.1 0.0 2.5e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Rap_GAP PF02145.10 EMC96199.1 - 2.7e-41 141.0 0.0 4.5e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EMC96199.1 - 5.6e-23 81.5 2.2 7.9e-21 74.5 0.2 2.3 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.3 EMC96199.1 - 1.2e-12 47.0 0.0 2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) TRAPPC9-Trs120 PF08626.6 EMC96201.1 - 1.1e-57 195.2 0.0 2e-55 187.7 0.0 3.6 2 1 0 2 2 2 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Apc5 PF12862.2 EMC96201.1 - 0.06 13.1 0.0 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 WW PF00397.21 EMC96202.1 - 4.7e-06 26.3 3.2 0.00064 19.5 1.8 3.0 2 0 0 2 2 2 2 WW domain TauD PF02668.11 EMC96203.1 - 1.1e-32 113.7 0.0 2e-32 112.8 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.1 EMC96204.1 - 8.5e-21 74.6 0.0 2.4e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMC96204.1 - 1.5e-15 57.2 0.0 4e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_61 PF03443.9 EMC96205.1 - 9.9e-80 267.4 0.0 1.8e-79 266.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NmrA PF05368.8 EMC96207.1 - 9.1e-26 90.5 0.0 1.1e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC96207.1 - 2.9e-16 60.0 0.0 4.9e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMC96207.1 - 1.6e-05 24.0 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMC96207.1 - 7.7e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NMT PF01233.14 EMC96207.1 - 0.024 14.2 0.0 0.086 12.4 0.0 1.8 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain 3Beta_HSD PF01073.14 EMC96207.1 - 0.039 12.6 0.0 0.06 12.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMC96207.1 - 0.069 13.4 0.0 4.9 7.4 0.0 2.9 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMC96207.1 - 0.084 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMN_dh PF01070.13 EMC96208.1 - 3.6e-103 345.1 0.0 4.7e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMC96208.1 - 8.6e-19 67.1 0.0 1.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMC96208.1 - 6.4e-07 28.6 0.0 1.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMC96208.1 - 1.4e-05 24.1 0.0 0.0028 16.6 0.0 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 EMC96208.1 - 0.0022 17.5 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein NMO PF03060.10 EMC96208.1 - 0.017 14.3 0.2 0.039 13.1 0.1 1.6 1 0 0 1 1 1 0 Nitronate monooxygenase NUDIX PF00293.23 EMC96209.1 - 6.7e-15 54.9 0.2 2.1e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain VTC PF09359.5 EMC96210.1 - 2.7e-90 302.2 0.3 4.5e-90 301.4 0.2 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EMC96210.1 - 7.8e-24 84.9 0.7 7.8e-24 84.9 0.5 2.8 3 1 0 3 3 3 1 SPX domain DUF202 PF02656.10 EMC96210.1 - 9.7e-10 38.5 4.5 2.2e-09 37.4 3.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) IncA PF04156.9 EMC96210.1 - 0.11 12.0 1.6 0.93 9.0 0.1 2.6 2 0 0 2 2 2 0 IncA protein Ribosomal_L28e PF01778.12 EMC96213.1 - 3e-27 95.3 1.0 5.6e-27 94.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EMC96213.1 - 9e-18 64.2 20.5 9e-18 64.2 14.2 3.2 1 1 1 2 2 2 1 Mak16 protein C-terminal region CENP-T PF15511.1 EMC96213.1 - 0.0065 15.7 18.7 0.0091 15.2 12.9 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T YccJ PF13993.1 EMC96214.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 YccJ-like protein RNA12 PF10443.4 EMC96215.1 - 2.4e-162 540.3 0.0 3.1e-162 539.9 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EMC96215.1 - 8.4e-07 28.9 0.0 1.1e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 EMC96215.1 - 0.00024 20.6 0.0 0.00051 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 EMC96215.1 - 0.00048 20.1 0.3 0.0095 15.9 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain DUF2487 PF10673.4 EMC96215.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) RRM_5 PF13893.1 EMC96215.1 - 0.022 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC96215.1 - 0.088 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_31 PF01055.21 EMC96216.1 - 2.2e-142 474.9 6.2 2.8e-142 474.6 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4246 PF14033.1 EMC96217.1 - 1.1e-156 522.3 0.0 1.3e-156 522.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PUF PF00806.14 EMC96218.1 - 1.4e-37 125.0 1.1 4.9e-07 28.8 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.6 EMC96218.1 - 0.054 14.1 0.0 0.27 11.9 0.0 2.0 2 0 0 2 2 2 0 Regulator of ribonuclease activity B Aldo_ket_red PF00248.16 EMC96219.1 - 1.5e-47 161.8 0.0 2.1e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cauli_VI PF01693.11 EMC96220.1 - 4.8e-34 116.1 2.5 1.2e-17 63.6 0.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EMC96220.1 - 2.4e-24 86.1 0.8 1.9e-17 63.8 0.0 2.3 2 0 0 2 2 2 2 RNase H DUF202 PF02656.10 EMC96221.1 - 0.04 14.1 7.0 0.25 11.6 4.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Abhydrolase_6 PF12697.2 EMC96223.1 - 3.6e-23 82.6 1.3 6.1e-23 81.9 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC96223.1 - 0.00027 20.7 0.0 0.00088 19.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC96223.1 - 0.066 12.7 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold LSPR PF06049.7 EMC96223.1 - 0.12 11.8 0.2 3.6 7.4 0.0 3.2 3 0 0 3 3 3 0 Coagulation Factor V LSPD Repeat Ndr PF03096.9 EMC96223.1 - 0.15 10.5 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family ADH_zinc_N PF00107.21 EMC96224.1 - 3.5e-05 23.3 0.0 6.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EMC96224.1 - 0.002 18.1 0.3 0.0031 17.5 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N_2 PF13602.1 EMC96224.1 - 0.091 13.6 0.0 0.23 12.3 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Catalase PF00199.14 EMC96225.1 - 9.5e-10 37.7 0.0 5.1e-09 35.2 0.0 2.0 1 1 0 1 1 1 1 Catalase Glyco_hydro_76 PF03663.9 EMC96226.1 - 1.6e-144 481.9 24.8 2e-144 481.5 17.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Meth_synt_2 PF01717.13 EMC96227.1 - 4.9e-13 48.7 0.0 4.2e-09 35.8 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMC96227.1 - 0.0014 18.0 0.2 1.2 8.3 0.0 3.2 3 1 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Mak10 PF04112.8 EMC96229.1 - 3.1e-45 153.4 0.0 5.5e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase CbiX PF01903.12 EMC96229.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 CbiX ATP-synt_Eps PF04627.8 EMC96230.1 - 1e-23 82.6 2.1 1.5e-23 82.0 1.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain VirE2 PF07229.7 EMC96230.1 - 0.056 11.8 0.1 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 VirE2 DUF3618 PF12277.3 EMC96232.1 - 0.05 13.6 0.5 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) GRIM-19 PF06212.7 EMC96232.1 - 0.12 12.0 0.2 0.64 9.7 0.0 2.2 3 0 0 3 3 3 0 GRIM-19 protein DUF3116 PF11313.3 EMC96233.1 - 0.13 11.9 0.1 0.32 10.6 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3116) POC1 PF10450.4 EMC96233.1 - 0.15 10.8 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 POC1 chaperone UPF0061 PF02696.9 EMC96238.1 - 2.6e-123 411.9 0.0 3.2e-123 411.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF2142 PF09913.4 EMC96239.1 - 0.089 11.4 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) BTB PF00651.26 EMC96241.1 - 4.3e-10 39.5 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF4407 PF14362.1 EMC96241.1 - 0.0039 16.1 8.5 0.0056 15.6 5.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Cast PF10174.4 EMC96241.1 - 0.0084 14.2 6.7 0.012 13.7 4.6 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone WEMBL PF05701.6 EMC96241.1 - 0.01 14.3 15.2 0.015 13.8 10.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 EMC96241.1 - 0.014 12.7 8.7 0.019 12.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.10 EMC96241.1 - 0.026 14.5 9.4 0.041 13.9 6.5 1.2 1 0 0 1 1 1 0 Fez1 DUF972 PF06156.8 EMC96241.1 - 0.027 14.7 6.2 0.034 14.4 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EMC96241.1 - 0.081 11.8 8.1 0.13 11.2 5.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EMC96241.1 - 0.098 12.2 4.2 0.18 11.3 2.9 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EMC96241.1 - 0.13 10.0 1.7 0.16 9.7 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KLRAQ PF10205.4 EMC96241.1 - 0.16 12.0 6.5 0.29 11.1 4.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein LRS4 PF10422.4 EMC96241.1 - 0.23 10.7 6.7 0.36 10.1 4.7 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TraG_N PF07916.6 EMC96241.1 - 0.35 9.2 3.9 0.49 8.7 2.7 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region IFT57 PF10498.4 EMC96241.1 - 0.62 8.7 5.5 0.3 9.7 0.2 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ADIP PF11559.3 EMC96241.1 - 1.2 8.9 13.6 0.2 11.5 0.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EMC96241.1 - 2.1 8.0 14.8 0.4 10.4 2.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC PF04632.7 EMC96241.1 - 3.8 5.8 7.6 4.8 5.4 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mnd1 PF03962.10 EMC96241.1 - 4.4 6.9 11.6 11 5.6 8.1 1.6 1 1 0 1 1 1 0 Mnd1 family AATF-Che1 PF13339.1 EMC96241.1 - 6.8 6.8 11.5 1e+02 3.0 8.0 2.2 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Seryl_tRNA_N PF02403.17 EMC96241.1 - 7.7 6.5 8.6 15 5.6 4.7 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EMC96241.1 - 8.6 5.9 9.4 18 4.8 2.5 2.6 1 1 1 2 2 2 0 Septum formation initiator ECH PF00378.15 EMC96242.1 - 1.3e-26 93.1 0.0 1.6e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2346 PF09803.4 EMC96243.1 - 8.3e-06 25.5 2.5 1.5e-05 24.7 1.7 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Polysacc_deac_1 PF01522.16 EMC96244.1 - 1.4e-14 53.7 0.0 2.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Tropomyosin_1 PF12718.2 EMC96246.1 - 0.0019 18.0 0.5 0.0039 17.0 0.4 1.5 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EMC96246.1 - 0.029 13.4 0.8 0.051 12.6 0.6 1.4 1 0 0 1 1 1 0 Tropomyosin Uds1 PF15456.1 EMC96246.1 - 0.039 13.9 1.3 0.052 13.5 0.3 1.6 2 0 0 2 2 2 0 Up-regulated During Septation IBR PF01485.16 EMC96247.1 - 2.8e-18 65.5 30.6 1.5e-11 44.0 0.6 3.9 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 EMC96247.1 - 9.6e-16 57.6 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EMC96247.1 - 4.6e-06 26.3 6.3 4.6e-06 26.3 4.3 3.7 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EMC96247.1 - 0.00039 20.1 7.1 0.00039 20.1 5.0 3.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC96247.1 - 0.0015 18.5 8.2 0.0015 18.5 5.7 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC96247.1 - 0.0024 17.5 2.9 0.0024 17.5 2.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EMC96247.1 - 0.0044 16.6 7.5 0.0044 16.6 5.2 4.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC96247.1 - 0.015 15.1 2.1 0.015 15.1 1.5 4.0 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING C1_4 PF07975.7 EMC96247.1 - 3.7 7.6 25.8 8.7 6.4 3.8 3.8 3 1 0 3 3 3 0 TFIIH C1-like domain PAP2 PF01569.16 EMC96248.1 - 5.4e-14 51.9 2.7 6e-14 51.8 1.3 1.5 1 1 0 1 1 1 1 PAP2 superfamily DUF2372 PF10178.4 EMC96249.1 - 0.0065 16.5 0.0 0.025 14.6 0.0 1.9 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2372) ADH_N PF08240.7 EMC96252.1 - 4.4e-26 90.7 0.8 7.8e-26 89.9 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC96252.1 - 3.4e-13 49.2 0.0 6.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC96252.1 - 0.0064 17.3 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EMC96252.1 - 0.014 15.4 0.4 0.037 14.1 0.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FA_desaturase PF00487.19 EMC96253.1 - 4.9e-23 81.8 17.4 8.3e-23 81.1 12.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EMC96253.1 - 5e-09 36.3 0.0 8.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Meth_synt_2 PF01717.13 EMC96254.1 - 6.7e-25 87.7 0.0 3.6e-16 59.0 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMC96254.1 - 2.9e-09 36.6 0.0 0.011 14.9 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Uroplakin_II PF07353.7 EMC96255.1 - 0.00062 19.1 2.0 0.00083 18.7 1.4 1.1 1 0 0 1 1 1 1 Uroplakin II TGT PF01702.13 EMC96257.1 - 0.58 9.3 4.3 3.3 6.9 0.5 2.1 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase Hist_deacetyl PF00850.14 EMC96258.1 - 5.5e-88 295.2 0.1 1.1e-87 294.3 0.1 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EMC96258.1 - 1.4e-38 132.1 0.0 2.3e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain AHS2 PF02626.10 EMC96259.1 - 4.1e-75 252.5 0.0 6.2e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EMC96259.1 - 2.2e-58 197.0 0.0 3.9e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EMC96259.1 - 5e-33 113.4 0.0 2.3e-32 111.3 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AHS1 PF02682.11 EMC96259.1 - 3.4e-30 105.0 0.0 7.8e-30 103.8 0.0 1.6 2 0 0 2 2 2 1 Allophanate hydrolase subunit 1 Biotin_carb_C PF02785.14 EMC96259.1 - 2.9e-29 101.2 0.0 6e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EMC96259.1 - 1.4e-15 57.5 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EMC96259.1 - 2.8e-13 49.2 1.0 1e-12 47.5 0.7 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EMC96259.1 - 7.2e-10 38.1 0.0 3.5e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMC96259.1 - 3.3e-08 33.1 0.0 6.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EMC96259.1 - 0.00068 19.1 0.0 0.0015 18.0 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EMC96259.1 - 0.00081 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EMC96259.1 - 0.0016 18.0 1.3 1.2 8.8 0.1 2.8 2 0 0 2 2 2 2 Biotin-lipoyl like ATP-grasp_5 PF13549.1 EMC96259.1 - 0.12 11.5 0.0 0.35 10.0 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain HlyD_2 PF12700.2 EMC96259.1 - 0.13 11.4 0.6 10 5.1 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein LamB_YcsF PF03746.11 EMC96260.1 - 7.6e-63 211.8 0.0 8.8e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family GFO_IDH_MocA PF01408.17 EMC96261.1 - 9.7e-20 71.2 0.0 1.6e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMC96261.1 - 6.4e-09 35.6 0.2 1.6e-08 34.3 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EMC96261.1 - 4.4e-07 30.2 0.0 9.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EMC96261.1 - 9.7e-05 22.6 0.0 0.00037 20.7 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EMC96261.1 - 0.071 13.0 0.1 0.27 11.1 0.2 1.8 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2012 PF09430.5 EMC96262.1 - 1.9e-26 92.2 0.0 2.6e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF445 PF04286.7 EMC96266.1 - 0.81 9.1 26.5 0.19 11.2 15.5 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF445) APG6 PF04111.7 EMC96266.1 - 2.5 7.0 18.5 1.7 7.5 11.3 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 Acetyltransf_13 PF13880.1 EMC96267.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase FTHFS PF01268.14 EMC96267.1 - 0.16 9.9 0.0 0.18 9.7 0.0 1.0 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Cation_efflux PF01545.16 EMC96268.1 - 3.3e-31 108.4 0.6 4.5e-31 107.9 0.4 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2985 PF11204.3 EMC96269.1 - 7.3e-26 89.7 3.5 1.4e-25 88.8 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sugar_tr PF00083.19 EMC96269.1 - 2.2 6.7 6.7 0.16 10.5 0.5 1.8 2 0 0 2 2 2 0 Sugar (and other) transporter Aldo_ket_red PF00248.16 EMC96270.1 - 3.4e-64 216.3 0.0 4e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2207 PF09972.4 EMC96271.1 - 0.029 12.9 0.1 0.039 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.1 EMC96271.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction HD_5 PF13487.1 EMC96271.1 - 0.043 13.7 1.7 20 5.2 1.8 2.7 2 1 0 2 2 2 0 HD domain DUF4231 PF14015.1 EMC96271.1 - 0.088 12.7 0.4 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF1469 PF07332.6 EMC96271.1 - 0.17 11.6 1.3 0.29 10.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) LIN37 PF15306.1 EMC96271.1 - 0.19 11.7 4.7 0.31 11.0 3.3 1.4 1 0 0 1 1 1 0 LIN37 Col_cuticle_N PF01484.12 EMC96271.1 - 0.29 10.8 2.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF346 PF03984.8 EMC96273.1 - 3.3e-05 23.2 23.6 0.016 14.6 0.0 7.0 7 0 0 7 7 7 3 Repeat of unknown function (DUF346) Ecm33 PF12454.3 EMC96273.1 - 0.15 11.9 1.3 0.27 11.1 0.9 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Cyclin PF08613.6 EMC96274.1 - 2.8e-29 102.4 0.0 4.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMC96274.1 - 0.0013 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 EMC96275.1 - 5.1e-10 38.8 11.2 0.017 14.9 0.0 8.4 10 0 0 10 10 10 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EMC96275.1 - 1.1e-05 25.0 9.3 0.22 11.6 0.0 6.7 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EMC96275.1 - 0.00051 20.2 13.0 0.0056 16.9 0.2 6.1 6 2 1 7 7 7 2 HEAT repeats Ribosomal_S5_C PF03719.10 EMC96275.1 - 0.0028 16.8 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain V-ATPase_H_C PF11698.3 EMC96275.1 - 0.088 12.7 0.1 0.91 9.4 0.0 2.8 2 0 0 2 2 2 0 V-ATPase subunit H HEAT_EZ PF13513.1 EMC96275.1 - 1 9.9 16.0 0.34 11.4 0.2 5.3 5 1 1 6 6 6 0 HEAT-like repeat DUF500 PF04366.7 EMC96276.1 - 6.6e-40 135.4 0.0 9.3e-40 134.9 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF500) dCMP_cyt_deam_1 PF00383.17 EMC96277.1 - 2.6e-07 30.2 0.1 1.2e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region ORC5_C PF14630.1 EMC96279.1 - 5.7e-67 226.0 0.0 8.5e-67 225.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EMC96279.1 - 1.4e-11 44.7 0.5 2.2e-10 40.8 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC96279.1 - 0.00081 19.5 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMC96279.1 - 0.0042 15.9 0.0 0.0058 15.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain RNA12 PF10443.4 EMC96279.1 - 0.019 13.4 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein Dendrin PF15498.1 EMC96279.1 - 0.066 11.7 0.9 0.097 11.1 0.6 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Arch_ATPase PF01637.13 EMC96279.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase GFO_IDH_MocA PF01408.17 EMC96280.1 - 4.1e-14 53.1 0.0 7.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Het-C PF07217.6 EMC96280.1 - 0.085 11.0 0.0 0.69 8.0 0.0 1.9 1 1 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Abhydrolase_6 PF12697.2 EMC96281.1 - 4.9e-17 62.5 0.2 6.2e-17 62.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC96281.1 - 3.4e-07 30.1 0.1 4.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC96281.1 - 1.1e-06 28.3 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMC96281.1 - 0.0054 16.9 0.1 0.0068 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydro_lipase PF04083.11 EMC96281.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF915 PF06028.6 EMC96281.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) TIG PF01833.19 EMC96282.1 - 4.8e-12 45.7 3.7 1.1e-11 44.6 1.8 2.2 2 0 0 2 2 2 1 IPT/TIG domain Racemase_4 PF13615.1 EMC96282.1 - 0.068 13.4 0.3 0.3 11.3 0.0 2.2 3 0 0 3 3 3 0 Putative alanine racemase Velvet PF11754.3 EMC96285.1 - 8e-64 214.9 0.0 1.2e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Velvet factor ZF-HD_dimer PF04770.7 EMC96286.1 - 0.46 10.5 2.9 2.7 8.1 0.3 2.3 2 0 0 2 2 2 0 ZF-HD protein dimerisation region ACBP PF00887.14 EMC96287.1 - 2e-25 88.2 0.1 3.7e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 EMC96287.1 - 0.021 14.9 0.8 0.038 14.1 0.1 1.7 2 0 0 2 2 2 0 FERM central domain Sec39 PF08314.6 EMC96287.1 - 0.043 11.7 0.2 0.052 11.4 0.2 1.0 1 0 0 1 1 1 0 Secretory pathway protein Sec39 THOC7 PF05615.8 EMC96287.1 - 0.056 13.7 5.6 2.5 8.3 1.2 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Atg14 PF10186.4 EMC96287.1 - 6.2 5.6 9.3 0.47 9.3 0.8 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MFS_1 PF07690.11 EMC96288.1 - 9.1e-38 129.8 37.8 9.1e-38 129.8 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 EMC96289.1 - 1.5e-30 106.4 0.8 1.9e-30 106.0 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.13 EMC96290.1 - 7.3e-22 77.4 0.1 1.3e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC96290.1 - 2.3e-09 36.9 11.2 4.4e-09 36.1 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EMC96291.1 - 1.5e-82 277.5 24.6 1.8e-82 277.3 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96291.1 - 1.7e-13 50.0 44.6 2.2e-12 46.3 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3188 PF11384.3 EMC96291.1 - 0.25 10.9 5.7 1.5 8.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Amidohydro_2 PF04909.9 EMC96292.1 - 4.7e-15 55.8 0.1 5.3e-15 55.7 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Mito_carr PF00153.22 EMC96293.1 - 1.9e-55 184.5 6.0 1.9e-19 69.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 EMC96294.1 - 3.1e-45 154.4 44.4 1.1e-44 152.6 29.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC96294.1 - 1.9e-21 75.8 14.8 1.9e-21 75.8 10.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC96294.1 - 1.8e-09 36.7 8.5 1.8e-09 36.7 5.9 3.2 3 1 1 4 4 4 1 Sugar (and other) transporter dCMP_cyt_deam_1 PF00383.17 EMC96295.1 - 6.7e-12 44.9 2.1 1.1e-11 44.2 1.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EMC96295.1 - 0.0014 18.2 0.3 0.0015 18.2 0.2 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 EMC96295.1 - 0.23 11.3 1.5 0.35 10.7 1.0 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase SUI1 PF01253.17 EMC96296.1 - 1.6e-14 53.4 0.0 3.5e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 EMC96296.1 - 0.0024 17.4 0.1 0.005 16.4 0.1 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein AMP-binding PF00501.23 EMC96297.1 - 8.8e-81 271.4 0.0 1.1e-80 271.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.18 EMC96298.1 - 4.8e-21 75.0 17.5 5.9e-21 74.8 12.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Polysacc_synt_C PF14667.1 EMC96298.1 - 0.39 10.5 9.2 0.032 14.0 2.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF4231 PF14015.1 EMC96298.1 - 2.8 7.9 10.4 4.2 7.3 2.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF3624 PF12292.3 EMC96298.1 - 5.1 7.5 10.5 0.28 11.5 2.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) WLM PF08325.5 EMC96299.1 - 2.2e-45 154.8 0.0 3.7e-45 154.1 0.0 1.4 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EMC96299.1 - 0.00014 21.6 0.3 0.0003 20.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EMC96299.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EMC96299.1 - 0.053 13.5 0.4 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Baculo_PEP_C PF04513.7 EMC96300.1 - 2e-06 27.6 19.5 0.074 12.8 2.5 4.8 4 1 1 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 EMC96300.1 - 0.00062 19.8 13.1 12 6.0 0.0 6.3 3 1 1 5 5 5 1 Syntaxin WXG100 PF06013.7 EMC96300.1 - 0.031 14.2 7.7 1.5 8.8 0.1 5.5 3 1 1 4 4 4 0 Proteins of 100 residues with WXG FlaC_arch PF05377.6 EMC96300.1 - 0.11 12.4 8.2 12 5.9 0.0 6.2 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) Sugarporin_N PF11471.3 EMC96300.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.7 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension NPV_P10 PF05531.7 EMC96300.1 - 0.46 10.7 19.8 5.9 7.2 0.0 6.5 4 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 EMC96300.1 - 0.64 9.4 28.9 0.045 13.2 5.7 4.7 3 2 1 4 4 4 0 Intermediate filament protein Allexi_40kDa PF05549.6 EMC96300.1 - 0.74 9.0 14.2 0.29 10.3 0.3 4.4 3 2 1 5 5 5 0 Allexivirus 40kDa protein DUF948 PF06103.6 EMC96300.1 - 0.99 9.3 11.5 7.9 6.4 0.2 5.8 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF948) TIP49 PF06068.8 EMC96301.1 - 5e-173 575.3 0.4 5.8e-173 575.1 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EMC96301.1 - 6.2e-08 31.9 1.1 0.00027 20.0 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EMC96301.1 - 5.9e-07 29.7 0.4 0.0025 18.0 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EMC96301.1 - 4.1e-05 22.5 0.3 6.9e-05 21.8 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EMC96301.1 - 0.00074 19.6 0.2 0.13 12.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC96301.1 - 0.0008 19.4 0.2 0.0084 16.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMC96301.1 - 0.0012 18.7 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EMC96301.1 - 0.0027 16.9 0.9 0.058 12.5 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMC96301.1 - 0.04 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EMC96301.1 - 0.056 12.9 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EMC96301.1 - 0.078 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMC96301.1 - 0.11 12.2 0.4 14 5.3 0.0 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EMC96301.1 - 0.22 11.0 1.0 24 4.5 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain Molybdopterin PF00384.17 EMC96302.1 - 2.8e-72 243.8 0.0 6e-70 236.1 0.0 2.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EMC96302.1 - 3.4e-19 68.4 0.1 9.6e-19 66.9 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EMC96302.1 - 5.1e-19 67.2 0.1 1.4e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EMC96302.1 - 7.5e-14 51.6 0.1 1.8e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EMC96302.1 - 8.8e-09 35.0 0.6 8.8e-09 35.0 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EMC96302.1 - 0.0056 16.4 0.0 0.76 9.5 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Cys_Met_Meta_PP PF01053.15 EMC96303.1 - 7.1e-152 505.1 0.0 8.2e-152 504.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMC96303.1 - 8.6e-10 38.1 0.1 1.4e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EMC96303.1 - 2.2e-09 36.7 0.0 3.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMC96303.1 - 4.4e-08 32.2 0.1 7.4e-08 31.5 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMC96303.1 - 1.2e-06 27.9 0.0 2.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EMC96303.1 - 0.00014 20.2 0.1 0.00019 19.8 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase CPSase_L_D2 PF02786.12 EMC96303.1 - 0.061 12.5 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GDC-P PF02347.11 EMC96303.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein TRAPPC10 PF12584.3 EMC96304.1 - 5.6e-18 64.8 0.0 1.4e-17 63.5 0.0 1.6 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 QCR10 PF09796.4 EMC96305.1 - 5e-21 74.1 0.0 6.3e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Na_H_Exchanger PF00999.16 EMC96307.1 - 7.4e-42 143.2 17.9 9.5e-42 142.8 12.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family adh_short_C2 PF13561.1 EMC96308.1 - 6.7e-29 101.3 0.0 7.7e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC96308.1 - 1.7e-18 67.1 1.5 2.3e-18 66.6 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 EMC96308.1 - 0.041 13.5 0.8 0.067 12.8 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PP1 PF07430.6 EMC96308.1 - 0.044 13.3 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 Phloem filament protein PP1 TehB PF03848.9 EMC96308.1 - 0.053 12.6 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.2 EMC96308.1 - 0.077 13.5 0.2 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.8 EMC96308.1 - 0.1 12.3 0.2 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) ADH_zinc_N PF00107.21 EMC96309.1 - 2.4e-23 82.1 0.4 4.3e-23 81.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC96309.1 - 1.2e-11 44.3 0.0 2e-10 40.3 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMC96309.1 - 1.6e-11 45.1 0.0 5.3e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrmE_N PF10396.4 EMC96309.1 - 0.12 12.3 0.0 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus Abhydrolase_6 PF12697.2 EMC96311.1 - 2.2e-15 57.1 0.1 3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC96311.1 - 6.7e-10 38.8 0.4 5.3e-09 35.9 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC96311.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase AA_permease_2 PF13520.1 EMC96312.1 - 3.4e-44 151.0 45.9 4.5e-44 150.6 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC96312.1 - 4e-21 74.9 37.6 5.8e-21 74.3 26.1 1.2 1 0 0 1 1 1 1 Amino acid permease Alk_phosphatase PF00245.15 EMC96313.1 - 9.9e-68 228.7 0.1 1.9e-67 227.8 0.1 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EMC96313.1 - 2.3e-05 23.7 0.9 0.00035 19.8 0.1 2.4 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EMC96313.1 - 0.00012 21.4 0.0 0.00025 20.4 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMC96313.1 - 0.00048 18.6 0.1 0.00071 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Peptidase_M4 PF01447.13 EMC96313.1 - 0.026 14.6 1.5 0.19 11.8 0.1 2.8 2 1 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain Metalloenzyme PF01676.13 EMC96313.1 - 0.072 12.4 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily XRCC4 PF06632.7 EMC96314.1 - 1.2e-09 37.5 1.4 1.2e-09 37.4 1.0 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Baculo_PEP_C PF04513.7 EMC96314.1 - 0.01 15.6 2.2 0.018 14.8 1.5 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3585 PF12130.3 EMC96314.1 - 0.012 15.4 5.2 0.012 15.4 3.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) PAXIP1_C PF15364.1 EMC96314.1 - 0.015 15.2 0.1 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein FliD_C PF07195.7 EMC96314.1 - 0.018 14.3 1.0 0.031 13.5 0.7 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus BACON PF13004.2 EMC96314.1 - 0.13 12.5 0.2 0.66 10.2 0.1 2.1 2 1 0 2 2 2 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal RNA_pol_Rpc82 PF05645.8 EMC96319.1 - 8.2e-37 127.1 0.0 2.5e-31 109.1 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EMC96319.1 - 4.8e-13 48.7 0.2 2.4e-09 36.9 0.1 3.2 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EMC96319.1 - 2.2e-09 36.7 1.1 0.00062 19.2 0.0 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 EMC96319.1 - 0.00043 19.9 0.1 0.013 15.2 0.0 2.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Senescence PF06911.7 EMC96319.1 - 0.00095 18.9 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Senescence-associated protein HTH_DeoR PF08220.7 EMC96319.1 - 0.042 13.3 0.2 11 5.6 0.0 3.8 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain Peptidase_M16_C PF05193.16 EMC96320.1 - 3.7e-16 59.3 0.0 5.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMC96320.1 - 2.4e-13 50.0 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Transcrip_reg PF01709.15 EMC96321.1 - 4.4e-58 196.1 0.7 5.1e-58 195.9 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator PolyA_pol PF01743.15 EMC96321.1 - 0.047 13.8 0.1 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 Poly A polymerase head domain E1-E2_ATPase PF00122.15 EMC96322.1 - 1.6e-16 60.0 0.0 4.7e-16 58.5 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMC96322.1 - 8.8e-15 55.6 0.0 7.2e-14 52.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC96322.1 - 3.5e-09 37.1 0.0 1e-08 35.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC96322.1 - 1.3e-05 25.0 0.0 4e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC96322.1 - 0.008 15.7 0.1 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMC96322.1 - 0.073 12.9 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase UPF0640 PF15114.1 EMC96322.1 - 0.076 12.5 0.2 7.5 6.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 NfeD PF01957.13 EMC96322.1 - 0.23 11.5 3.2 0.15 12.1 0.6 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Cupin_1 PF00190.17 EMC96323.1 - 1.3e-28 99.2 0.6 2.3e-13 49.7 0.1 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EMC96323.1 - 3.9e-24 83.9 0.3 1.1e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EMC96323.1 - 1.2e-09 37.4 0.1 0.002 17.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMC96323.1 - 3.1e-08 33.3 0.1 0.0013 18.4 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EMC96323.1 - 2.5e-07 30.4 0.0 2.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 EMC96323.1 - 0.0002 20.7 0.0 0.00057 19.3 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.2 EMC96323.1 - 0.00042 19.9 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 Cupin ARD PF03079.9 EMC96323.1 - 0.011 15.6 0.1 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 ARD/ARD' family Cupin_4 PF08007.7 EMC96323.1 - 0.031 13.5 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein 2OG-FeII_Oxy_5 PF13759.1 EMC96323.1 - 0.041 14.1 0.4 5.3 7.3 0.0 2.8 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase Auxin_BP PF02041.11 EMC96323.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Auxin binding protein Cellulase PF00150.13 EMC96325.1 - 1.2e-20 73.9 7.7 2.4e-20 72.8 5.4 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 EMC96325.1 - 0.064 12.5 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TMF_TATA_bd PF12325.3 EMC96326.1 - 0.53 10.0 13.0 0.13 11.9 2.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Macoilin PF09726.4 EMC96326.1 - 0.99 7.6 14.0 1.8 6.7 9.7 1.3 1 0 0 1 1 1 0 Transmembrane protein Fib_alpha PF08702.5 EMC96326.1 - 5.7 7.0 8.1 34 4.5 3.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Es2 PF09751.4 EMC96327.1 - 5.6e-85 286.2 1.7 6.6e-85 286.0 1.2 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 JmjC PF02373.17 EMC96328.1 - 3.7e-40 136.7 0.5 8.3e-40 135.5 0.4 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 EMC96328.1 - 1.7e-20 72.9 2.3 3.8e-20 71.8 1.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC96328.1 - 4.2e-18 65.3 1.9 8e-18 64.4 1.3 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 EMC96328.1 - 3.9e-14 51.8 2.5 1.2e-13 50.3 1.8 1.9 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EMC96328.1 - 0.63 9.7 5.9 1.5 8.5 4.1 1.6 1 0 0 1 1 1 0 PHD-finger VHS PF00790.14 EMC96329.1 - 0.00079 19.0 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 VHS domain CTD_bind PF04818.8 EMC96329.1 - 0.017 15.3 0.0 0.065 13.4 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 EMC96329.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Inhibitor_I9 PF05922.11 EMC96330.1 - 0.015 15.8 0.0 0.017 15.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 Methyltransf_3 PF01596.12 EMC96330.1 - 0.093 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 O-methyltransferase HLH PF00010.21 EMC96331.1 - 1e-11 44.3 0.0 1.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 EMC96331.1 - 0.006 16.2 0.3 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 EMC96331.1 - 0.36 10.8 2.6 0.95 9.4 0.0 2.3 2 1 0 2 2 2 0 bZIP transcription factor SAE2 PF08573.5 EMC96332.1 - 2.7e-20 72.8 0.2 5.5e-20 71.8 0.1 1.5 1 1 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus F-box PF00646.28 EMC96333.1 - 0.00028 20.4 0.3 0.00048 19.6 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC96333.1 - 0.00068 19.3 0.2 0.0013 18.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like zf-CCHC PF00098.18 EMC96334.1 - 3.3e-23 80.4 27.6 7e-09 35.2 1.4 4.8 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.1 EMC96334.1 - 1.4e-06 27.9 16.4 0.0046 16.6 0.1 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.1 EMC96334.1 - 8.7e-05 22.1 18.1 0.1 12.2 0.7 3.1 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.1 EMC96334.1 - 0.00016 21.2 17.3 0.18 11.4 0.9 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 EMC96334.1 - 0.21 11.1 0.1 0.21 11.1 0.1 3.2 3 0 0 3 3 3 0 Zinc knuckle DUF1777 PF08648.7 EMC96335.1 - 9.4e-22 77.6 21.3 1.2e-21 77.2 14.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) tRNA-synt_1c PF00749.16 EMC96337.1 - 2.2e-94 315.6 0.0 3.8e-94 314.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMC96337.1 - 6.7e-31 107.2 0.0 1.5e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Zn_clus PF00172.13 EMC96338.1 - 3.5e-10 39.6 9.5 6.5e-10 38.7 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMC96338.1 - 3.7e-09 35.6 0.1 5.6e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-DHHC PF01529.15 EMC96338.1 - 3.6 6.9 5.9 4.4 6.6 3.0 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase Amidohydro_4 PF13147.1 EMC96339.1 - 0.03 14.3 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase Macro PF01661.16 EMC96340.1 - 3.3e-38 130.2 0.2 5.3e-38 129.5 0.2 1.3 1 0 0 1 1 1 1 Macro domain Ank_2 PF12796.2 EMC96341.1 - 4e-13 49.5 1.7 5.3e-06 26.6 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC96341.1 - 9.3e-12 45.1 3.2 1.2e-05 25.6 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC96341.1 - 3.7e-10 39.0 0.9 0.0035 17.4 0.0 4.2 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.25 EMC96341.1 - 2e-09 36.8 1.6 0.0011 18.6 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC96341.1 - 8.7e-09 35.3 1.5 0.023 14.9 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EMC96341.1 - 0.0007 19.1 0.1 0.0054 16.3 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain DUF2353 PF09789.4 EMC96341.1 - 0.0076 15.5 2.9 0.012 14.9 2.0 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DNase_II PF03265.10 EMC96341.1 - 0.23 10.4 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Deoxyribonuclease II GAS PF13851.1 EMC96341.1 - 1.6 7.9 10.1 4.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 EMC96341.1 - 2 7.8 7.2 1.1 8.7 2.8 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF3584 PF12128.3 EMC96341.1 - 6.8 3.8 14.0 2.9 5.1 7.2 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) Complex1_LYR_1 PF13232.1 EMC96342.1 - 2.1e-07 31.0 1.1 5e-07 29.8 0.8 1.7 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMC96342.1 - 8.2e-07 28.7 1.4 1.9e-06 27.5 0.9 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) BTB PF00651.26 EMC96343.1 - 1.2e-12 47.8 0.1 2.2e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Phage_GPL PF05926.6 EMC96343.1 - 0.017 14.9 0.2 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) DUF3373 PF11853.3 EMC96343.1 - 0.47 8.9 2.0 0.69 8.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) BTB PF00651.26 EMC96344.1 - 1.2e-14 54.2 0.0 2.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SNF2_N PF00176.18 EMC96345.1 - 5.2e-70 235.6 0.0 1.2e-68 231.1 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC96345.1 - 6.6e-17 61.1 0.0 4.7e-16 58.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMC96345.1 - 6.2e-05 21.9 2.5 0.12 11.1 0.0 3.5 3 1 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 Glyco_tranf_2_3 PF13641.1 EMC96347.1 - 2.9e-19 69.8 0.0 5.2e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMC96347.1 - 1.6e-08 34.4 0.8 1.6e-08 34.4 0.6 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMC96347.1 - 7.8e-06 25.6 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMC96347.1 - 0.00015 21.0 0.0 0.00038 19.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 COX14 PF14880.1 EMC96347.1 - 0.043 13.4 1.1 0.4 10.3 0.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Noc2 PF03715.8 EMC96348.1 - 0.058 12.2 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Noc2p family Apc15p PF05841.6 EMC96349.1 - 1.2e-15 58.3 1.2 1.2e-15 58.3 0.8 2.2 2 0 0 2 2 2 1 Apc15p protein SNARE PF05739.14 EMC96350.1 - 1.2e-07 31.3 1.7 1.7e-07 30.7 1.2 1.3 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EMC96350.1 - 0.0037 16.7 0.0 0.0089 15.4 0.0 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF1241 PF06840.6 EMC96350.1 - 0.03 13.5 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) RabGAP-TBC PF00566.13 EMC96351.1 - 3.7e-36 124.6 2.6 7.4e-36 123.6 1.8 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EMC96351.1 - 2.3e-10 40.1 0.0 1e-06 28.1 0.0 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF3548) 2-Hacid_dh_C PF02826.14 EMC96352.1 - 6.9e-44 149.1 0.0 1.3e-43 148.2 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC96352.1 - 8.2e-07 28.5 0.0 2.4e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.16 EMC96352.1 - 0.0041 16.7 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.1 EMC96352.1 - 0.01 16.1 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain ApbA PF02558.11 EMC96352.1 - 0.085 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LIM PF00412.17 EMC96355.1 - 1.3e-21 76.4 33.9 5.8e-10 39.0 0.8 5.4 6 0 0 6 6 6 4 LIM domain PH_4 PF15404.1 EMC96356.1 - 3.2e-63 212.6 0.0 8.3e-63 211.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EMC96356.1 - 9.5e-19 66.6 1.3 1.3e-18 66.2 0.1 1.8 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.24 EMC96356.1 - 5.3e-06 26.5 0.3 0.002 18.2 0.0 3.9 3 2 0 3 3 3 1 PH domain PH_6 PF15406.1 EMC96356.1 - 0.021 14.8 2.9 0.069 13.2 0.0 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain NAD_binding_2 PF03446.10 EMC96357.1 - 4e-35 121.0 0.0 5.3e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMC96357.1 - 1.6e-23 83.0 0.0 2.8e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF3636 PF12331.3 EMC96358.1 - 1.2e-37 128.7 0.3 2.6e-37 127.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) SPRY PF00622.23 EMC96359.1 - 2.4e-17 63.1 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Phosphorylase PF00343.15 EMC96360.1 - 0 1078.5 0.6 0 1078.3 0.4 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CTP_transf_1 PF01148.15 EMC96361.1 - 1.3e-80 270.8 29.5 1.5e-80 270.5 20.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family adh_short PF00106.20 EMC96362.1 - 4.5e-26 91.7 4.0 4e-25 88.6 2.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC96362.1 - 2e-14 53.6 0.2 2.9e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC96362.1 - 9.5e-10 38.2 0.1 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMC96362.1 - 2.5e-07 30.7 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMC96362.1 - 0.00056 19.9 0.4 0.0032 17.5 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC96362.1 - 0.0044 15.9 0.1 0.0066 15.3 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Cullin PF00888.17 EMC96363.1 - 2.3e-188 627.4 14.4 2.3e-188 627.4 10.0 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EMC96363.1 - 1.5e-29 101.6 5.1 5.8e-29 99.7 3.6 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WGG PF10273.4 EMC96363.1 - 0.25 11.4 4.9 24 5.0 0.1 4.0 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 HEAT_EZ PF13513.1 EMC96364.1 - 8.6e-27 92.9 10.3 3.2e-11 43.3 0.0 9.4 8 2 3 11 11 10 5 HEAT-like repeat HEAT_2 PF13646.1 EMC96364.1 - 6e-25 87.3 5.8 2.2e-07 31.0 0.0 8.3 4 3 3 8 8 8 6 HEAT repeats HEAT PF02985.17 EMC96364.1 - 6.2e-21 72.5 13.0 0.0013 18.6 0.0 10.5 12 0 0 12 12 12 5 HEAT repeat Vac14_Fab1_bd PF12755.2 EMC96364.1 - 7.7e-14 51.8 0.1 0.0012 19.1 0.0 6.9 6 2 2 9 9 9 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EMC96364.1 - 5e-09 35.9 0.1 7.9e-07 28.9 0.0 4.2 3 1 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EMC96364.1 - 8.3e-07 29.0 0.0 3.4 7.4 0.0 5.8 4 3 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EMC96364.1 - 6.2e-05 22.4 0.4 19 4.5 0.0 6.4 4 2 0 5 5 5 0 CLASP N terminal Adaptin_N PF01602.15 EMC96364.1 - 6.4e-05 21.4 0.1 0.015 13.6 0.0 3.1 2 1 1 4 4 4 1 Adaptin N terminal region Xpo1 PF08389.7 EMC96364.1 - 0.0037 17.1 0.1 2.1 8.2 0.0 4.5 4 2 0 4 4 4 1 Exportin 1-like protein Arm PF00514.18 EMC96364.1 - 0.0046 16.7 4.0 2.8 7.8 0.0 5.6 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EMC96364.1 - 0.05 14.0 2.6 33 5.3 0.0 5.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.2 EMC96364.1 - 0.09 12.7 0.0 11 6.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF937 PF06078.6 EMC96364.1 - 0.15 12.2 1.1 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF937) TPK_catalytic PF04263.11 EMC96366.1 - 4.9e-23 81.0 0.0 7e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EMC96366.1 - 7.4e-18 64.0 0.1 1.3e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF2746 PF10874.3 EMC96366.1 - 0.2 11.8 0.6 15 5.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) CHCH PF06747.8 EMC96367.1 - 1.3e-07 31.3 3.3 2.2e-07 30.6 2.3 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EMC96367.1 - 0.0025 17.8 1.1 0.0045 17.0 0.8 1.3 1 0 0 1 1 1 1 GCK domain Hydrolase PF00702.21 EMC96368.1 - 6.8e-24 85.4 0.0 2.6e-23 83.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMC96368.1 - 5.7e-22 77.8 0.0 1.4e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMC96368.1 - 5.4e-19 69.1 0.0 1.1e-18 68.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC96368.1 - 0.00036 20.4 0.4 0.017 15.0 0.0 3.1 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC96368.1 - 0.0014 18.2 0.2 0.042 13.4 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase FixQ PF05545.6 EMC96368.1 - 7.1 6.3 7.9 18 5.0 0.7 3.1 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ MRJP PF03022.11 EMC96369.1 - 4.1e-22 78.7 0.0 6.4e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EMC96369.1 - 0.082 12.2 0.0 0.24 10.7 0.0 1.8 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Pkinase PF00069.20 EMC96370.1 - 8.3e-72 241.4 0.0 1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC96370.1 - 1.4e-31 109.4 0.0 1.8e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC96370.1 - 1.1e-05 24.6 0.0 2.2e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC96370.1 - 0.00018 20.5 0.0 0.0075 15.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EMC96370.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC96370.1 - 0.0062 15.8 0.1 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 RIO1 family G-alpha PF00503.15 EMC96371.1 - 2.8e-130 434.5 1.3 3.3e-130 434.2 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC96371.1 - 4.5e-16 58.5 1.0 4.8e-11 42.2 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC96371.1 - 1.4e-05 24.3 0.2 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC96371.1 - 0.00075 19.9 0.1 0.76 10.2 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 EMC96371.1 - 0.035 14.0 0.0 1.4 8.8 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC96371.1 - 0.042 13.2 0.1 1.9 7.9 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EMC96371.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Chitin_synth_2 PF03142.10 EMC96372.1 - 1.1e-23 83.4 1.5 4.7e-23 81.3 0.4 2.9 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMC96372.1 - 2.2e-16 60.1 3.2 2.2e-16 60.1 2.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC96372.1 - 2.5e-16 60.1 0.0 4.9e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC96372.1 - 0.00014 21.5 0.0 0.023 14.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 SNF2_N PF00176.18 EMC96373.1 - 7.4e-73 244.9 0.2 1.9e-72 243.6 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC96373.1 - 3.7e-14 52.3 0.1 1.1e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EMC96373.1 - 1.3e-05 24.8 0.3 1.3e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain DEAD PF00270.24 EMC96373.1 - 2.2e-05 24.0 0.1 6e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMC96373.1 - 0.03 14.1 0.0 0.088 12.6 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 EMC96373.1 - 0.043 13.6 0.6 0.1 12.4 0.4 1.6 1 0 0 1 1 1 0 Ring finger domain Zn-ribbon_8 PF09723.5 EMC96373.1 - 0.18 11.7 4.8 0.18 11.7 1.5 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4 PF00097.20 EMC96373.1 - 0.45 10.2 3.8 0.17 11.5 0.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.7 EMC96373.1 - 0.5 10.5 3.6 0.33 11.1 0.4 2.2 2 0 0 2 2 2 0 CHY zinc finger PI3_PI4_kinase PF00454.22 EMC96374.1 - 4.5e-32 111.3 0.0 9e-32 110.4 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.22 EMC96375.1 - 3.3e-16 58.3 3.0 5.6e-16 57.6 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger IncA PF04156.9 EMC96375.1 - 0.0034 17.0 0.2 0.013 15.1 0.4 1.7 2 0 0 2 2 2 1 IncA protein TF_Zn_Ribbon PF08271.7 EMC96375.1 - 0.0058 15.9 0.5 0.01 15.1 0.4 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Kinesin-relat_1 PF12711.2 EMC96375.1 - 0.03 14.7 1.8 0.066 13.6 1.3 1.5 1 1 0 1 1 1 0 Kinesin motor E2R135 PF11570.3 EMC96375.1 - 0.06 13.4 1.2 0.13 12.3 0.8 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 DZR PF12773.2 EMC96375.1 - 0.083 12.7 0.9 0.2 11.4 0.6 1.5 1 1 0 1 1 1 0 Double zinc ribbon Pox_A_type_inc PF04508.7 EMC96375.1 - 0.091 12.5 2.0 1.4 8.9 0.4 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat BMFP PF04380.8 EMC96375.1 - 0.12 12.5 7.8 0.11 12.6 3.7 2.0 2 0 0 2 2 2 0 Membrane fusogenic activity DUF904 PF06005.7 EMC96375.1 - 0.14 12.4 2.1 0.24 11.6 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CALCOCO1 PF07888.6 EMC96375.1 - 0.15 10.3 1.5 0.21 9.8 1.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DivIC PF04977.10 EMC96375.1 - 0.76 9.3 3.7 1.5 8.3 1.8 1.9 1 1 1 2 2 2 0 Septum formation initiator DUF1136 PF06582.7 EMC96375.1 - 3.2 7.5 5.4 2 8.2 0.2 3.1 3 1 0 3 3 2 0 Repeat of unknown function (DUF1136) Cupin_2 PF07883.6 EMC96376.1 - 1.7e-15 56.2 0.1 3.8e-09 35.9 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EMC96376.1 - 7.8e-08 31.5 0.0 0.0018 17.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EMC96376.1 - 5e-05 22.7 0.1 0.32 10.4 0.0 2.6 2 0 0 2 2 2 2 Cupin Cupin_6 PF12852.2 EMC96376.1 - 7e-05 22.5 0.1 0.0053 16.3 0.0 2.3 2 0 0 2 2 2 1 Cupin EutQ PF06249.7 EMC96376.1 - 0.00079 18.9 0.0 0.062 12.8 0.0 2.8 2 1 1 3 3 3 1 Ethanolamine utilisation protein EutQ MannoseP_isomer PF01050.13 EMC96376.1 - 0.0011 18.6 0.0 0.068 12.7 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase CENP-C_C PF11699.3 EMC96376.1 - 0.0023 17.8 0.0 0.16 12.0 0.0 2.8 2 1 1 3 3 3 1 Mif2/CENP-C like FdtA PF05523.6 EMC96376.1 - 0.0037 16.7 0.1 0.08 12.4 0.0 2.3 2 0 0 2 2 2 1 WxcM-like, C-terminal AraC_binding PF02311.14 EMC96376.1 - 0.0054 16.4 0.3 0.037 13.7 0.3 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain AraC_binding_2 PF14525.1 EMC96376.1 - 0.043 13.3 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 AraC-binding-like domain Cupin_4 PF08007.7 EMC96376.1 - 0.095 11.9 0.5 11 5.1 0.0 2.5 3 0 0 3 3 3 0 Cupin superfamily protein Abhydrolase_3 PF07859.8 EMC96377.1 - 4.2e-08 33.0 0.0 5.7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC96377.1 - 4e-05 23.3 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EMC96377.1 - 0.009 14.6 0.0 0.016 13.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EMC96377.1 - 0.036 12.7 1.7 0.094 11.4 1.1 1.6 1 1 0 1 1 1 0 Carboxylesterase family GMC_oxred_N PF00732.14 EMC96378.1 - 2.8e-55 187.5 0.0 6.5e-55 186.3 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC96378.1 - 3e-38 131.3 0.0 5.1e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EMC96378.1 - 8.8e-05 21.5 0.9 0.00013 21.0 0.6 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EMC96378.1 - 0.0045 15.9 5.7 0.016 14.1 1.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC96378.1 - 0.012 15.6 1.8 0.14 12.2 0.5 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC96378.1 - 0.04 12.7 3.5 0.21 10.3 2.0 2.0 2 0 0 2 2 2 0 FAD binding domain zf-H2C2_2 PF13465.1 EMC96379.1 - 1.4e-08 34.5 5.1 0.0003 20.9 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC96379.1 - 3.2e-06 27.1 19.8 0.00022 21.3 1.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC96379.1 - 8.8e-06 25.6 14.0 0.009 16.2 0.6 3.9 3 1 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 EMC96379.1 - 0.015 15.4 1.7 2.2 8.4 0.2 3.1 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 EMC96379.1 - 0.018 14.7 0.8 0.018 14.7 0.5 3.1 2 1 1 3 3 3 0 BED zinc finger Zn-ribbon_8 PF09723.5 EMC96379.1 - 0.3 11.0 6.1 23 5.0 2.4 3.5 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMC96379.1 - 0.84 9.6 19.2 0.099 12.5 1.3 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.2 EMC96379.1 - 2.1 8.2 7.8 3.4e+02 1.1 5.4 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_2 PF12756.2 EMC96379.1 - 2.6 8.1 7.8 0.27 11.3 0.5 2.5 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) HypA PF01155.14 EMC96379.1 - 3.1 7.5 7.3 80 2.9 5.0 2.5 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_jaz PF12171.3 EMC96379.1 - 3.1 8.0 6.0 0.96 9.6 0.4 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EMC96379.1 - 3.8 7.3 16.1 2.5 7.8 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Ribosomal_L44 PF00935.14 EMC96379.1 - 6.9 6.7 10.3 2.4 8.2 2.5 2.7 2 1 0 2 2 2 0 Ribosomal protein L44 zf-MYND PF01753.13 EMC96379.1 - 7.1 6.6 9.1 0.74 9.7 0.8 2.6 2 0 0 2 2 2 0 MYND finger SprT-like PF10263.4 EMC96379.1 - 8.3 6.0 9.1 3.1 7.4 1.0 2.3 1 1 1 2 2 2 0 SprT-like family RNHCP PF12647.2 EMC96379.1 - 9.9 6.0 12.3 2.1 8.2 2.3 3.2 1 1 2 3 3 3 0 RNHCP domain SWIRM PF04433.12 EMC96380.1 - 3.7e-35 119.9 0.1 8.5e-35 118.7 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EMC96380.1 - 6.6e-07 29.2 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC96380.1 - 0.00024 21.1 0.1 0.00054 20.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EMC96380.1 - 0.0015 18.0 5.8 0.12 11.8 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, ZZ type FAD_binding_3 PF01494.14 EMC96381.1 - 3.2e-10 39.6 1.0 0.0018 17.3 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 EMC96381.1 - 1.3e-05 24.2 0.0 2.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMC96381.1 - 2.1e-05 24.4 0.2 5.9e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC96381.1 - 0.00027 20.8 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC96381.1 - 0.00062 18.7 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EMC96381.1 - 0.0015 17.1 0.1 0.0034 15.9 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMC96381.1 - 0.0031 17.6 0.1 0.014 15.5 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC96381.1 - 0.0034 16.5 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EMC96381.1 - 0.0065 15.4 0.4 0.013 14.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC96381.1 - 0.11 12.9 0.4 0.6 10.5 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EMC96382.1 - 1.5e-12 47.7 0.1 2.5e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC96382.1 - 1.1e-07 31.6 0.6 2.4e-07 30.6 0.4 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC96382.1 - 0.00021 21.1 0.0 0.00065 19.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMC96382.1 - 0.045 12.6 0.1 0.064 12.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMC96382.1 - 0.063 13.3 0.3 0.098 12.7 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EMC96383.1 - 5.5e-74 249.3 28.7 6.4e-74 249.1 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96383.1 - 8.6e-24 83.8 36.9 3.9e-20 71.8 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC96383.1 - 4.8e-06 25.2 33.4 0.00038 18.9 5.2 3.6 2 2 2 4 4 4 4 MFS/sugar transport protein p450 PF00067.17 EMC96385.1 - 2e-64 217.8 0.0 3.2e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Tad PF13400.1 EMC96385.1 - 0.073 13.1 1.4 0.15 12.0 1.0 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like IstB_IS21 PF01695.12 EMC96386.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Peptidase_S24 PF00717.18 EMC96387.1 - 1.7e-07 30.7 0.4 1.6e-06 27.6 0.1 2.5 2 2 1 3 3 3 1 Peptidase S24-like Peptidase_S26 PF10502.4 EMC96387.1 - 3.4e-07 29.8 0.0 5.5e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S29 PF02907.10 EMC96387.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Iso_dh PF00180.15 EMC96388.1 - 2.9e-82 276.4 0.0 3.3e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4285 PF14113.1 EMC96388.1 - 0.016 15.2 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) FYVE PF01363.16 EMC96389.1 - 8.9e-23 79.9 20.7 2.3e-16 59.4 3.0 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 EMC96389.1 - 9.8e-05 21.8 0.9 0.00031 20.2 0.2 2.2 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 EMC96389.1 - 0.00014 21.6 3.5 0.00014 21.6 2.4 3.5 3 1 0 3 3 3 1 AN1-like Zinc finger zf-Di19 PF05605.7 EMC96389.1 - 0.005 16.9 12.8 0.023 14.8 0.0 3.6 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 EMC96389.1 - 0.11 12.3 12.5 0.45 10.4 0.6 3.4 3 0 0 3 3 3 0 IBR domain APG6 PF04111.7 EMC96389.1 - 0.36 9.8 9.0 0.67 8.9 0.1 3.2 3 0 0 3 3 3 0 Autophagy protein Apg6 FlxA PF14282.1 EMC96389.1 - 0.37 10.7 8.7 0.062 13.2 0.5 2.6 2 0 0 2 2 2 0 FlxA-like protein Allexi_40kDa PF05549.6 EMC96389.1 - 0.38 10.0 3.0 9.8 5.3 0.0 3.0 3 0 0 3 3 3 0 Allexivirus 40kDa protein DUF2757 PF10955.3 EMC96389.1 - 0.6 10.3 9.3 0.39 10.9 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) TMF_TATA_bd PF12325.3 EMC96389.1 - 1.2 8.8 6.7 0.27 10.9 0.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-C2HC5 PF06221.8 EMC96389.1 - 1.3 8.8 18.4 0.56 9.9 0.2 4.3 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type DUF393 PF04134.7 EMC96389.1 - 4.7 8.3 8.1 18 6.4 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function, DUF393 zf-C2H2 PF00096.21 EMC96389.1 - 9.3 6.8 27.6 8 7.0 3.2 5.9 5 1 1 6 6 6 0 Zinc finger, C2H2 type NAD_binding_7 PF13241.1 EMC96390.1 - 5.8e-32 110.0 0.0 9e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EMC96390.1 - 1e-26 92.0 0.0 1.6e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EMC96390.1 - 4.7e-14 51.0 0.2 9.4e-14 50.1 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 EMC96390.1 - 0.0014 18.7 0.1 0.0023 18.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMC96390.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMC96390.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GLTP PF08718.6 EMC96391.1 - 1.7e-44 151.4 0.0 2.4e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Gp58 PF07902.6 EMC96391.1 - 0.045 11.9 0.0 0.054 11.6 0.0 1.0 1 0 0 1 1 1 0 gp58-like protein Methyltransf_10 PF05971.7 EMC96392.1 - 2.1e-60 204.4 0.0 3e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EMC96392.1 - 4.3e-06 26.7 0.0 1.4e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC96392.1 - 5.3e-05 22.6 0.0 9.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMC96392.1 - 8.1e-05 23.1 0.0 0.00021 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC96392.1 - 0.0092 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EMC96392.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EMC96392.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMC96392.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain BAR_2 PF10455.4 EMC96394.1 - 8.5e-54 182.4 0.2 1.2e-53 181.8 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EMC96394.1 - 5.2e-17 62.1 5.2 1.1e-15 57.7 3.6 2.0 1 1 0 1 1 1 1 BAR domain GAS PF13851.1 EMC96394.1 - 0.084 12.0 3.5 0.57 9.3 0.0 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding MCM PF00493.18 EMC96397.1 - 0.00056 18.8 0.2 0.00087 18.1 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family Cytochrom_C_2 PF01322.15 EMC96397.1 - 0.18 12.3 1.4 0.5 10.9 0.0 2.1 2 1 0 2 2 2 0 Cytochrome C' DUF2681 PF10883.3 EMC96398.1 - 1.6 8.9 7.8 0.95 9.7 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Mito_carr PF00153.22 EMC96401.1 - 3.3e-29 100.4 1.0 7.8e-15 54.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.16 EMC96405.1 - 2.6e-70 237.5 0.4 8.4e-67 225.9 0.0 2.2 2 0 0 2 2 2 2 Amidase adh_short PF00106.20 EMC96406.1 - 2.9e-28 98.8 0.0 3.7e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC96406.1 - 1.1e-15 57.7 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC96406.1 - 3.4e-14 53.2 0.1 4.4e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMC96406.1 - 4.3e-09 35.6 0.1 5.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EMC96406.1 - 5.2e-07 29.3 0.2 1.2e-06 28.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC96406.1 - 0.0066 16.4 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMC96406.1 - 0.02 15.0 0.1 0.036 14.1 0.0 1.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EMC96406.1 - 0.028 14.2 1.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 ThiF family WW PF00397.21 EMC96407.1 - 1.9e-07 30.7 7.0 3.5e-07 29.9 4.9 1.5 1 0 0 1 1 1 1 WW domain Dehydrin PF00257.14 EMC96407.1 - 0.091 13.0 3.2 0.13 12.6 2.2 1.2 1 0 0 1 1 1 0 Dehydrin MFS_1 PF07690.11 EMC96408.1 - 1.2e-35 122.8 60.4 1.8e-35 122.3 40.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC96408.1 - 2.4e-07 29.3 17.7 3.3e-07 28.8 12.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC96408.1 - 1.2e-06 27.4 43.3 0.00032 19.3 3.1 3.5 2 1 1 3 3 3 3 Sugar (and other) transporter Plasmid_stab_B PF10784.4 EMC96408.1 - 0.11 12.0 0.1 0.4 10.3 0.1 1.9 1 0 0 1 1 1 0 Plasmid stability protein FAD_binding_6 PF00970.19 EMC96409.1 - 3.4e-10 39.9 0.0 7.7e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMC96409.1 - 0.00046 20.7 0.0 0.0011 19.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Suc_Fer-like PF06999.7 EMC96411.1 - 7.9e-46 156.9 0.0 1e-45 156.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Metallophos PF00149.23 EMC96412.1 - 4.1e-09 36.1 0.8 1.2e-08 34.5 0.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.22 EMC96413.1 - 1.8e-49 167.5 0.1 1.7e-25 89.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EMC96413.1 - 2.2e-23 82.8 60.8 8.5e-15 54.6 19.7 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EMC96413.1 - 4.7e-20 72.7 0.0 4.1e-05 23.6 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EMC96413.1 - 7.9e-09 34.9 1.2 0.001 18.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EMC96413.1 - 2.4e-08 33.4 1.7 0.0037 16.5 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMC96413.1 - 5.4e-06 26.8 0.6 0.14 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMC96413.1 - 1.3e-05 24.4 0.1 0.068 12.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EMC96413.1 - 0.0011 18.8 0.2 6.5 6.7 0.0 4.5 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EMC96413.1 - 0.0033 17.4 2.4 1.5 8.7 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EMC96413.1 - 0.0041 16.5 0.5 1.2 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMC96413.1 - 0.011 15.1 0.6 4.1 6.7 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EMC96413.1 - 0.016 15.3 0.2 0.94 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMC96413.1 - 0.018 14.9 0.4 2.2 8.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMC96413.1 - 0.026 14.3 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMC96413.1 - 0.028 13.9 2.2 5.4 6.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 EMC96413.1 - 0.04 13.3 2.0 2.3 7.6 0.3 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.1 EMC96413.1 - 0.096 11.7 0.0 3.3 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EMC96413.1 - 0.12 12.8 0.1 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 EMC96413.1 - 0.23 11.6 0.0 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF4162 PF13732.1 EMC96413.1 - 0.29 11.6 0.0 0.66 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) G-alpha PF00503.15 EMC96413.1 - 0.71 8.4 0.0 2.5 6.6 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_13 PF13166.1 EMC96413.1 - 0.92 7.8 0.0 12 4.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMC96413.1 - 1.4 8.7 5.1 6.8 6.5 0.1 3.4 3 0 0 3 3 2 0 Part of AAA domain Zeta_toxin PF06414.7 EMC96413.1 - 4.4 6.3 5.0 22 4.0 0.2 2.7 3 0 0 3 3 3 0 Zeta toxin adh_short PF00106.20 EMC96415.1 - 9.4e-05 22.3 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC96415.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_26 PF13659.1 EMC96415.1 - 0.049 13.6 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Iso_dh PF00180.15 EMC96418.1 - 3.8e-98 328.6 0.0 4.6e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 EMC96419.1 - 1.9e-33 115.7 0.0 5.5e-33 114.2 0.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EMC96419.1 - 3.1e-07 30.1 0.3 1e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 HET PF06985.6 EMC96420.1 - 1.1e-09 38.5 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CAP_N PF01213.14 EMC96422.1 - 2.4e-80 270.1 13.6 3.4e-79 266.3 9.4 2.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EMC96422.1 - 8.4e-53 177.9 0.0 1.3e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EMC96422.1 - 0.017 14.5 1.4 0.072 12.4 0.3 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C zf-RING_2 PF13639.1 EMC96423.1 - 3e-15 55.7 7.5 3e-15 55.7 5.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC96423.1 - 5.1e-11 42.0 9.7 8.8e-09 34.9 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC96423.1 - 1e-07 31.9 2.9 1e-07 31.9 2.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC96423.1 - 1e-07 31.8 15.5 1.1e-07 31.7 4.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EMC96423.1 - 2.9e-07 30.3 7.7 9.7e-05 22.2 3.5 2.7 2 0 0 2 2 2 2 zinc-finger zf-C3HC4 PF00097.20 EMC96423.1 - 4.7e-07 29.3 15.5 5.2e-06 26.0 4.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC96423.1 - 5.1e-06 26.1 4.9 5.1e-06 26.1 3.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC96423.1 - 0.0019 17.9 2.6 0.0019 17.9 1.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 EMC96423.1 - 0.0038 16.9 1.0 0.0038 16.9 0.7 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Baculo_RING PF05883.6 EMC96423.1 - 0.033 14.0 0.8 0.033 14.0 0.5 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EMC96423.1 - 0.11 12.1 13.9 0.17 11.5 2.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMC96423.1 - 0.12 12.1 4.8 0.43 10.3 2.8 2.2 2 0 0 2 2 2 0 RING-type zinc-finger PHD PF00628.24 EMC96423.1 - 0.28 10.9 18.6 0.04 13.6 4.4 2.9 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.1 EMC96423.1 - 0.48 10.3 13.9 0.57 10.1 1.0 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EMC96423.1 - 0.77 9.5 12.3 2.2 8.0 0.5 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 DZR PF12773.2 EMC96423.1 - 1.3 8.8 9.7 0.53 10.1 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EMC96423.1 - 2.5 7.4 5.4 18 4.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 EMC96423.1 - 8.1 6.3 10.7 0.43 10.3 0.8 2.6 2 1 2 4 4 4 0 zinc-ribbons AA_permease PF00324.16 EMC96424.1 - 1.6e-127 425.7 45.3 1.8e-127 425.5 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMC96424.1 - 3.5e-39 134.5 48.6 4.6e-39 134.1 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 EMC96425.1 - 9.1e-35 120.1 25.5 3e-34 118.4 17.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96425.1 - 5.5e-29 100.9 49.9 1.4e-26 93.0 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EMC96425.1 - 0.031 12.9 7.9 0.049 12.3 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF791) ATG22 PF11700.3 EMC96425.1 - 0.11 10.9 29.4 0.0091 14.5 4.0 2.3 2 1 0 3 3 3 0 Vacuole effluxer Atg22 like Ion_trans_2 PF07885.11 EMC96426.1 - 2.5e-28 97.6 16.6 2.4e-17 62.3 2.3 3.3 4 0 0 4 4 4 2 Ion channel PPR_3 PF13812.1 EMC96427.1 - 5.5e-27 91.7 9.9 4.8e-05 23.3 0.1 11.1 11 0 0 11 11 11 7 Pentatricopeptide repeat domain PPR_2 PF13041.1 EMC96427.1 - 3.4e-23 81.3 0.4 2.3e-05 24.2 0.0 7.2 7 2 3 10 10 10 4 PPR repeat family PPR PF01535.15 EMC96427.1 - 7.6e-14 50.6 1.1 0.047 13.6 0.0 8.8 10 0 0 10 10 10 3 PPR repeat PPR_1 PF12854.2 EMC96427.1 - 2e-09 36.7 0.0 0.0062 15.9 0.0 6.1 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 EMC96427.1 - 0.0028 18.1 22.0 5.9 7.8 0.0 9.7 9 2 2 11 11 11 1 Tetratricopeptide repeat MFS_1 PF07690.11 EMC96428.1 - 2.2e-24 85.8 30.4 3.2e-24 85.2 21.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily COX14 PF14880.1 EMC96428.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.7 3 0 0 3 3 3 0 Cytochrome oxidase c assembly MFS_1 PF07690.11 EMC96429.1 - 8.9e-25 87.1 12.1 2.6e-19 69.1 0.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EMC96429.1 - 1.7e-18 66.7 2.4 4.2e-18 65.5 1.7 1.6 1 0 0 1 1 1 1 Nodulin-like Serinc PF03348.10 EMC96430.1 - 1.2e-167 558.0 1.1 1.3e-167 557.8 0.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FA_desaturase PF00487.19 EMC96430.1 - 0.071 12.5 11.8 0.23 10.8 0.0 3.1 2 1 0 2 2 2 0 Fatty acid desaturase DUF3481 PF11980.3 EMC96430.1 - 3.8 7.3 7.2 0.2 11.4 0.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3481) YlaC PF10777.4 EMC96430.1 - 4.5 6.8 6.5 5.8 6.4 0.9 2.3 2 0 0 2 2 2 0 Inner membrane protein YlaC TPP_enzyme_N PF02776.13 EMC96431.1 - 3.5e-39 134.0 0.0 1.1e-37 129.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMC96431.1 - 2.1e-18 66.4 0.0 6.7e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMC96431.1 - 2.8e-17 62.7 0.1 4.9e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CMD PF02627.15 EMC96432.1 - 3.2e-21 74.9 0.1 5.5e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DSPc PF00782.15 EMC96433.1 - 1.2e-10 41.0 0.0 2.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC96433.1 - 2.3e-05 23.8 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EMC96433.1 - 0.003 17.0 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EMC96433.1 - 0.0039 17.4 0.0 0.0097 16.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC96433.1 - 0.015 15.3 0.1 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate PGAP1 PF07819.8 EMC96434.1 - 1.2e-83 280.1 0.0 1.8e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EMC96434.1 - 4.3e-09 36.2 0.1 8.4e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC96434.1 - 1.4e-06 28.3 0.2 2.7e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC96434.1 - 0.0032 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EMC96434.1 - 0.0066 15.7 0.1 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) SCPU PF05229.10 EMC96434.1 - 0.016 15.3 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 Spore Coat Protein U domain LCAT PF02450.10 EMC96434.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 EMC96434.1 - 0.061 12.7 0.0 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF955 PF06114.8 EMC96434.1 - 0.099 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) ResIII PF04851.10 EMC96435.1 - 4.4e-23 82.0 0.0 9.3e-22 77.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC96435.1 - 5.5e-13 48.7 0.0 1.6e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC96435.1 - 8e-12 44.8 0.1 2.7e-11 43.1 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 EMC96435.1 - 0.0017 17.3 0.0 0.0033 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EMC96435.1 - 0.0018 18.4 0.0 0.0093 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Transglut_core PF01841.14 EMC96435.1 - 0.033 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily Helicase_C_2 PF13307.1 EMC96435.1 - 0.068 13.1 0.1 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain MIF4G PF02854.14 EMC96436.1 - 3.5e-58 196.4 0.3 5e-31 107.7 0.1 3.2 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.9 EMC96436.1 - 4.1e-51 173.1 5.8 4.1e-51 173.1 4.1 2.2 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Cyclin_N PF00134.18 EMC96438.1 - 0.0045 16.5 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Spc24 PF08286.6 EMC96439.1 - 1.4e-32 111.8 0.2 3.1e-31 107.5 0.0 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 APG6 PF04111.7 EMC96439.1 - 0.11 11.5 1.3 0.15 11.1 0.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF603 PF04645.7 EMC96439.1 - 0.11 12.3 0.3 0.17 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Fis1_TPR_C PF14853.1 EMC96440.1 - 5e-25 87.1 2.2 8.2e-25 86.4 1.6 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EMC96440.1 - 9.9e-17 59.9 0.0 1.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EMC96440.1 - 0.0015 18.3 1.5 0.0033 17.2 1.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC96440.1 - 0.0072 16.9 1.0 0.0072 16.9 0.7 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC96440.1 - 0.024 14.9 1.7 0.025 14.9 0.4 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC96440.1 - 0.06 13.0 0.2 0.095 12.3 0.2 1.3 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.1 EMC96440.1 - 0.078 13.4 0.4 0.43 11.1 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2636 PF11120.3 EMC96442.1 - 0.016 14.7 1.0 0.03 13.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2636) WD40 PF00400.27 EMC96447.1 - 2.5e-14 52.5 6.9 2e-05 24.2 0.0 7.9 9 0 0 9 9 9 3 WD domain, G-beta repeat DUF3639 PF12341.3 EMC96447.1 - 3.1e-10 39.8 1.7 3.1e-10 39.8 1.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) PQQ_3 PF13570.1 EMC96447.1 - 0.0054 16.9 3.0 0.53 10.6 0.0 3.9 3 0 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 EMC96447.1 - 0.017 14.7 0.1 37 4.1 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DNA_pol_alpha_N PF12254.3 EMC96447.1 - 0.08 12.7 2.0 0.22 11.3 1.4 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Coatomer_WDAD PF04053.9 EMC96447.1 - 0.31 9.7 0.1 2 7.1 0.0 2.1 1 1 1 3 3 3 0 Coatomer WD associated region CHZ PF09649.5 EMC96448.1 - 6.5e-16 57.2 1.8 6.5e-16 57.2 1.3 2.8 3 1 1 4 4 4 1 Histone chaperone domain CHZ Glu_synthase PF01645.12 EMC96450.1 - 1.9e-159 530.5 0.0 3.2e-159 529.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EMC96450.1 - 5.4e-138 459.6 0.0 7.7e-138 459.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EMC96450.1 - 1.3e-118 395.4 0.0 3.8e-118 393.9 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EMC96450.1 - 1.3e-66 223.4 2.2 2.4e-66 222.6 1.6 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EMC96450.1 - 1.1e-22 79.7 0.1 3e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EMC96450.1 - 1.6e-18 67.2 0.0 1.8e-17 63.9 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC96450.1 - 5e-09 36.5 0.2 0.0014 18.7 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC96450.1 - 1.7e-08 34.3 0.0 5.6e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC96450.1 - 5.1e-08 33.2 0.1 5.5e-05 23.5 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMC96450.1 - 1.3e-06 27.7 0.0 2.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMC96450.1 - 2.2e-05 23.5 0.5 0.00041 19.3 0.1 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMC96450.1 - 4.3e-05 22.1 0.1 4.3e-05 22.1 0.1 1.8 3 0 0 3 3 3 1 HI0933-like protein FMO-like PF00743.14 EMC96450.1 - 5.3e-05 21.6 0.2 0.0095 14.1 0.0 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 EMC96450.1 - 0.00074 18.6 0.2 0.0038 16.3 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EMC96450.1 - 0.00074 18.4 0.4 0.003 16.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EMC96450.1 - 0.0008 19.6 0.3 2.1 8.6 0.0 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.2 EMC96450.1 - 0.0011 18.1 1.0 0.0014 17.7 0.0 1.7 2 0 0 2 2 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMC96450.1 - 0.0016 18.0 0.0 0.046 13.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EMC96450.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain AdoHcyase_NAD PF00670.16 EMC96450.1 - 0.016 15.0 0.2 3.2 7.5 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.17 EMC96450.1 - 0.02 13.7 0.8 0.078 11.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EMC96450.1 - 0.025 14.2 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 EMC96450.1 - 0.035 13.8 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 1 0 FAD-NAD(P)-binding ApbA PF02558.11 EMC96450.1 - 0.088 12.2 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DJ-1_PfpI PF01965.19 EMC96450.1 - 0.14 11.5 0.1 1 8.8 0.0 2.2 1 1 1 2 2 2 0 DJ-1/PfpI family UDPG_MGDP_dh_N PF03721.9 EMC96450.1 - 0.21 10.9 0.0 0.47 9.8 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMC96450.1 - 0.45 10.1 2.2 0.37 10.4 0.0 2.0 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_63 PF03200.11 EMC96451.1 - 1.1e-229 764.4 0.1 8.6e-229 761.4 0.1 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EMC96451.1 - 3.5e-05 22.6 1.4 6.2e-05 21.8 1.0 1.3 1 0 0 1 1 1 1 Trehalase MMtag PF10159.4 EMC96452.1 - 5.9e-30 103.1 4.5 5.9e-30 103.1 3.1 2.9 2 1 0 2 2 2 1 Kinase phosphorylation protein HLH PF00010.21 EMC96455.1 - 1.1e-12 47.4 0.3 2.1e-12 46.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.7 EMC96455.1 - 0.014 14.9 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein AAA_32 PF13654.1 EMC96455.1 - 0.04 12.5 1.2 0.053 12.1 0.8 1.1 1 0 0 1 1 1 0 AAA domain WES_acyltransf PF03007.11 EMC96455.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain GrpE PF01025.14 EMC96455.1 - 0.42 10.1 5.1 0.28 10.7 1.2 1.9 1 1 1 2 2 2 0 GrpE DUF3886 PF13025.1 EMC96455.1 - 1.4 8.9 12.0 0.2 11.6 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) eIF-6 PF01912.13 EMC96456.1 - 2.6e-82 274.7 0.6 2.6e-82 274.7 0.4 1.5 2 0 0 2 2 2 1 eIF-6 family PUF PF00806.14 EMC96457.1 - 2.3e-62 203.0 6.5 4.1e-09 35.4 0.1 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.6 EMC96457.1 - 0.017 14.9 0.2 18 5.1 0.0 3.4 3 0 0 3 3 3 0 CPL (NUC119) domain SMI1_KNR4 PF09346.5 EMC96457.1 - 0.099 12.6 0.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) Fungal_trans PF04082.13 EMC96459.1 - 2.2e-24 85.7 0.4 3.5e-24 85.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC96459.1 - 1.1e-06 28.3 8.6 2.4e-06 27.3 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMC96460.1 - 6.3e-27 94.5 0.0 8.8e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC96460.1 - 3.7e-19 69.4 0.0 4.8e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMC96460.1 - 6.3e-06 26.3 0.1 1.9e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMC96460.1 - 4e-05 23.3 0.0 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMC96460.1 - 9.9e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC96460.1 - 0.0037 16.1 0.0 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1237 PF06824.6 EMC96461.1 - 2.3e-173 576.6 0.2 2.8e-173 576.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DUF605 PF04652.11 EMC96461.1 - 1.3 8.3 8.3 2 7.7 5.8 1.3 1 0 0 1 1 1 0 Vta1 like DAO PF01266.19 EMC96464.1 - 2.2e-56 191.2 1.3 3.8e-56 190.5 0.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC96464.1 - 1.3e-05 25.1 0.1 3.8e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC96464.1 - 0.0008 18.3 1.1 0.0036 16.2 0.8 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMC96464.1 - 0.0012 19.1 0.0 0.03 14.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC96464.1 - 0.002 18.0 0.3 2.5 7.9 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EMC96464.1 - 0.02 14.0 0.0 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Trp_halogenase PF04820.9 EMC96464.1 - 0.024 13.2 0.5 0.05 12.2 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Strep_67kDa_ant PF06100.6 EMC96464.1 - 0.042 12.2 0.1 0.073 11.4 0.1 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Actin PF00022.14 EMC96465.1 - 5.1e-159 528.9 0.0 5.8e-159 528.7 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EMC96465.1 - 0.036 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Arm PF00514.18 EMC96466.1 - 6.3e-08 32.1 0.6 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC96466.1 - 1e-07 32.1 0.5 1.9e-07 31.2 0.2 1.6 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 EMC96466.1 - 1.4e-06 28.6 1.9 2.1e-05 24.8 0.3 2.5 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EMC96466.1 - 2.8e-05 23.8 0.5 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat Ligase_CoA PF00549.14 EMC96466.1 - 0.038 13.5 0.1 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 CoA-ligase LPP20 PF02169.11 EMC96466.1 - 0.056 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein Rootletin PF15035.1 EMC96466.1 - 0.086 12.8 0.2 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Glyco_hydro_28 PF00295.12 EMC96468.1 - 6e-31 107.5 13.8 1.1e-22 80.4 2.5 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 28 RHIM PF12721.2 EMC96468.1 - 0.072 13.5 0.4 0.072 13.5 0.3 2.8 3 0 0 3 3 3 0 RIP homotypic interaction motif zf-HIT PF04438.11 EMC96469.1 - 0.017 14.7 6.9 0.036 13.7 4.8 1.6 1 1 0 1 1 1 0 HIT zinc finger C1_1 PF00130.17 EMC96469.1 - 0.34 10.6 10.1 0.23 11.1 0.5 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 EMC96469.1 - 2.3 8.1 8.0 6 6.7 5.6 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger p450 PF00067.17 EMC96471.1 - 7.5e-60 202.7 0.0 9.9e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rick_17kDa_Anti PF05433.10 EMC96473.1 - 0.002 17.7 16.9 0.0036 16.9 11.7 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF533 PF04391.7 EMC96473.1 - 0.02 14.2 0.6 0.036 13.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Gly-zipper_OmpA PF13436.1 EMC96473.1 - 0.02 14.5 2.2 0.04 13.5 1.5 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EMC96473.1 - 0.16 11.4 12.4 0.27 10.7 8.6 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EMC96473.1 - 8.5 6.1 16.7 3.3 7.4 9.3 1.9 1 1 1 2 2 2 0 Glycine zipper TatD_DNase PF01026.16 EMC96474.1 - 6e-22 78.0 0.0 9.3e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase DUF883 PF05957.8 EMC96477.1 - 0.17 12.3 6.2 0.29 11.5 3.8 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4175 PF13779.1 EMC96477.1 - 4.7 4.7 20.8 6 4.4 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mo-co_dimer PF03404.11 EMC96478.1 - 1.9e-56 189.2 0.0 4.1e-56 188.2 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EMC96478.1 - 1.7e-49 167.4 0.0 3e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EMC96478.1 - 2.8e-31 107.5 0.0 5.1e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMC96478.1 - 4.7e-25 88.2 0.0 1.1e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EMC96478.1 - 8.8e-24 83.1 0.1 1.8e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EMC96478.1 - 4.6e-05 23.3 0.1 0.0055 16.6 0.0 2.5 1 1 1 2 2 2 1 Ferric reductase NAD binding domain NIR_SIR PF01077.17 EMC96479.1 - 1.8e-30 105.3 0.0 3.3e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EMC96479.1 - 3.7e-28 98.7 0.1 7.1e-28 97.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EMC96479.1 - 2.2e-18 65.8 0.0 6.8e-18 64.3 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 EMC96479.1 - 3.4e-16 59.4 4.7 7.4e-15 55.1 0.3 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EMC96479.1 - 1.6e-13 50.5 4.1 1.4e-10 41.0 2.0 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 EMC96479.1 - 2e-13 49.6 0.1 7e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EMC96479.1 - 1.1e-10 40.9 0.0 2.9e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EMC96479.1 - 9.5e-10 38.8 0.1 1.3e-05 25.3 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMC96479.1 - 6.3e-05 22.2 0.0 0.062 12.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EMC96479.1 - 8.1e-05 22.4 0.4 0.5 10.1 0.0 3.5 2 2 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 EMC96479.1 - 0.00019 20.4 0.3 1.6 7.5 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EMC96479.1 - 0.0012 17.8 0.0 0.0083 15.0 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EMC96479.1 - 0.022 13.2 0.0 2.4 6.5 0.0 3.2 3 1 1 4 4 4 0 HI0933-like protein TrkA_N PF02254.13 EMC96479.1 - 0.26 11.2 0.8 19 5.2 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain Mit_KHE1 PF10173.4 EMC96481.1 - 2.7e-59 200.1 0.1 2.7e-59 200.1 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DUF745 PF05335.8 EMC96481.1 - 0.28 10.6 9.9 0.46 9.9 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tyrosinase PF00264.15 EMC96482.1 - 1.1e-45 156.4 6.2 1.1e-45 156.4 4.3 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase Cutinase PF01083.17 EMC96483.1 - 6.6e-47 159.5 7.0 7.8e-47 159.3 4.9 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMC96483.1 - 0.00014 21.3 0.5 0.0002 20.8 0.4 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 EMC96485.1 - 2.4e-23 83.2 0.2 6.8e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC96485.1 - 9.4e-15 54.7 0.0 4.9e-13 49.1 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC96485.1 - 5.1e-09 36.0 0.0 3.8e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 EMC96485.1 - 5.8e-06 25.5 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EMC96485.1 - 1.4e-05 24.6 0.0 4.4e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Chlorophyllase2 PF12740.2 EMC96485.1 - 0.008 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 EMC96485.1 - 0.023 14.3 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) DUF2305 PF10230.4 EMC96485.1 - 0.032 13.6 0.0 0.076 12.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Spo7 PF03907.8 EMC96486.1 - 7.9e-58 195.4 0.0 1.2e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein MFS_1 PF07690.11 EMC96487.1 - 7.7e-35 120.2 35.5 1.2e-34 119.6 24.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PMEI PF04043.10 EMC96488.1 - 0.017 14.9 0.4 0.017 14.9 0.3 2.3 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor PQQ_2 PF13360.1 EMC96489.1 - 3.4e-05 23.4 0.1 4.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 EMC96489.1 - 0.088 13.1 0.7 35 4.8 0.0 3.4 3 1 0 3 3 3 0 PQQ-like domain PQQ PF01011.16 EMC96489.1 - 0.11 12.1 0.2 6.1 6.5 0.1 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat Metallophos PF00149.23 EMC96490.1 - 3.3e-09 36.4 0.3 9.6e-09 34.9 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC96490.1 - 0.00068 19.4 0.0 0.0037 17.1 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Exonuc_VII_S PF02609.11 EMC96491.1 - 0.2 11.4 0.2 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Exonuclease VII small subunit Apolipoprotein PF01442.13 EMC96492.1 - 0.0011 18.5 13.3 0.0014 18.1 9.2 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Hydantoinase_B PF02538.9 EMC96492.1 - 0.007 14.6 1.2 0.0085 14.3 0.8 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Bac_GDH PF05088.7 EMC96492.1 - 0.072 10.4 7.7 0.088 10.1 5.3 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase PA26 PF04636.8 EMC96492.1 - 0.091 11.4 7.5 0.099 11.3 5.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ISG65-75 PF11727.3 EMC96492.1 - 0.18 10.8 23.0 0.41 9.6 14.7 1.9 1 1 1 2 2 2 0 Invariant surface glycoprotein Exonuc_VII_L PF02601.10 EMC96492.1 - 0.27 10.3 10.1 0.33 10.0 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DBINO PF13892.1 EMC96492.1 - 0.73 9.8 19.0 1.4 8.9 13.2 1.5 1 0 0 1 1 1 0 DNA-binding domain V_ATPase_I PF01496.14 EMC96492.1 - 0.94 7.2 7.8 1.2 6.9 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3974 PF13120.1 EMC96492.1 - 1.2 8.9 4.3 0.73 9.6 0.2 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3974) Borrelia_P83 PF05262.6 EMC96492.1 - 1.3 7.1 25.4 1.7 6.8 17.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HMG_box_2 PF09011.5 EMC96492.1 - 2 8.8 16.0 0.52 10.7 7.8 2.4 1 1 1 2 2 2 0 HMG-box domain Hid1 PF12722.2 EMC96492.1 - 2.2 5.8 18.2 2.6 5.6 12.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ARGLU PF15346.1 EMC96492.1 - 3.2 7.5 21.7 4.8 6.9 15.0 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Peptidase_C12 PF01088.16 EMC96493.1 - 2.7e-54 183.5 0.0 4.7e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NfeD PF01957.13 EMC96494.1 - 0.84 9.7 0.0 0.84 9.7 0.0 2.6 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Sugar_tr PF00083.19 EMC96496.1 - 2.4e-72 243.9 25.2 2.9e-72 243.6 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96496.1 - 1.6e-13 50.0 24.3 1.6e-13 50.0 16.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2489 PF10675.4 EMC96497.1 - 0.052 13.2 0.5 0.081 12.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) CUE PF02845.11 EMC96497.1 - 0.11 12.0 0.1 3 7.3 0.0 2.4 2 0 0 2 2 2 0 CUE domain Yip1 PF04893.12 EMC96498.1 - 4.4e-11 42.5 17.8 6.8e-11 41.9 12.3 1.4 1 1 0 1 1 1 1 Yip1 domain GTP_EFTU PF00009.22 EMC96499.1 - 2.5e-31 108.5 0.0 2.5e-31 108.5 0.0 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMC96499.1 - 4.8e-20 71.4 0.0 1.4e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMC96499.1 - 2.1e-10 40.5 6.0 2.6e-08 33.8 0.3 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC96499.1 - 1.8e-06 27.8 0.0 7.9e-06 25.8 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EMC96499.1 - 0.005 16.4 0.1 0.026 14.1 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EMC96499.1 - 0.0098 15.4 0.1 0.04 13.4 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EMC96499.1 - 0.013 15.4 0.0 0.013 15.4 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EMC96499.1 - 0.024 14.7 0.0 0.12 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain DSPc PF00782.15 EMC96502.1 - 1.4e-09 37.6 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EMC96502.1 - 0.014 14.3 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Synapsin_C PF02750.9 EMC96502.1 - 0.048 12.7 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Synapsin, ATP binding domain Y_phosphatase PF00102.22 EMC96502.1 - 0.049 12.9 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SecY PF00344.15 EMC96504.1 - 5.4e-93 311.6 8.4 7.2e-93 311.2 5.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EMC96504.1 - 2.4e-18 65.3 0.3 6.6e-18 63.9 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Ribosomal_L3 PF00297.17 EMC96505.1 - 2.8e-117 390.7 6.1 3.4e-117 390.5 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Myelin-PO_C PF10570.4 EMC96505.1 - 1.2 9.3 7.1 6.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Myelin-PO cytoplasmic C-term p65 binding region DUF867 PF05908.6 EMC96506.1 - 0.041 12.9 1.2 0.45 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF867) ATG16 PF08614.6 EMC96506.1 - 1.5 8.6 12.2 2.1 8.1 8.2 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SR-25 PF10500.4 EMC96506.1 - 2.5 7.5 23.3 0.17 11.3 12.4 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SLX9 PF15341.1 EMC96506.1 - 8.5 6.8 15.9 10 6.5 10.0 1.7 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Hpt PF01627.18 EMC96507.1 - 1.3e-12 47.4 0.2 3.9e-12 46.0 0.1 1.8 1 1 0 1 1 1 1 Hpt domain Aminotran_1_2 PF00155.16 EMC96510.1 - 2.8e-90 302.8 0.0 3.3e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II BING4CT PF08149.6 EMC96511.1 - 3.8e-40 135.2 0.0 5.9e-37 125.0 0.0 3.0 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EMC96511.1 - 4e-06 26.4 0.0 0.0018 18.0 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EMC96511.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Sulfate_transp PF00916.15 EMC96512.1 - 2.3e-53 181.0 11.2 9.7e-29 100.2 1.4 2.8 3 1 0 3 3 3 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMC96512.1 - 7.1e-29 99.3 2.5 2.4e-28 97.6 1.7 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMC96512.1 - 9.4e-16 57.2 0.0 1.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EMC96512.1 - 0.00041 20.3 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 STAS domain TctB PF07331.6 EMC96512.1 - 2.1 8.0 16.1 0.37 10.4 3.2 3.4 2 2 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family End3 PF12761.2 EMC96513.1 - 1.6e-70 236.7 1.9 2.2e-70 236.2 1.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EMC96513.1 - 2.7e-46 155.5 0.0 2e-45 152.7 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EMC96513.1 - 8.6e-08 30.9 0.6 6e-07 28.3 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMC96513.1 - 2.4e-07 30.2 0.1 2.8e-06 26.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EMC96513.1 - 2.1e-05 24.5 0.3 0.00016 21.7 0.1 2.5 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC96513.1 - 7.7e-05 22.2 1.4 0.0013 18.4 0.2 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EMC96513.1 - 0.00012 21.2 0.4 0.00043 19.4 0.1 2.1 2 0 0 2 2 1 1 EF hand DASH_Dad3 PF08656.5 EMC96513.1 - 0.039 13.6 0.4 4.3 7.1 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 AKNA PF12443.3 EMC96513.1 - 0.092 12.7 4.2 1.2 9.2 0.3 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor Phage_GP20 PF06810.6 EMC96513.1 - 0.1 12.0 4.8 0.14 11.6 0.6 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Mnd1 PF03962.10 EMC96513.1 - 0.13 11.9 4.2 0.86 9.2 3.9 1.6 2 0 0 2 2 2 0 Mnd1 family DUF641 PF04859.7 EMC96513.1 - 0.46 10.2 4.7 0.15 11.8 0.9 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Syntaxin-6_N PF09177.6 EMC96513.1 - 0.63 10.4 5.7 17 5.8 0.3 3.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal IFT57 PF10498.4 EMC96513.1 - 0.68 8.6 5.1 1.1 7.9 3.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FlxA PF14282.1 EMC96513.1 - 0.95 9.4 3.1 20 5.1 1.4 2.4 2 0 0 2 2 2 0 FlxA-like protein Fib_alpha PF08702.5 EMC96513.1 - 1.6 8.8 3.7 7.7 6.6 2.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 EMC96513.1 - 4 6.3 7.1 0.96 8.3 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 EMC96513.1 - 4.2 7.1 8.5 1.2 8.8 0.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Bap31 PF05529.7 EMC96513.1 - 4.4 6.7 4.9 9.3 5.6 3.4 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like CENP-Q PF13094.1 EMC96513.1 - 4.6 7.2 11.0 0.5 10.3 0.3 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EMC96513.1 - 5.4 6.5 10.1 2.9 7.4 4.0 2.1 2 0 0 2 2 2 0 IncA protein TSC22 PF01166.13 EMC96513.1 - 5.9 6.9 7.6 8.7 6.4 0.7 2.8 3 0 0 3 3 2 0 TSC-22/dip/bun family Prefoldin_2 PF01920.15 EMC96513.1 - 6.5 6.5 9.6 7.6 6.3 1.4 2.8 2 1 0 2 2 2 0 Prefoldin subunit Thiolase_N PF00108.18 EMC96514.1 - 1.2e-73 247.3 0.0 1.8e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC96514.1 - 1.6e-41 140.5 0.4 4.3e-41 139.1 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EMC96514.1 - 0.0015 18.1 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EMC96514.1 - 0.053 12.9 1.6 0.099 12.1 0.5 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Cupin_2 PF07883.6 EMC96515.1 - 0.066 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Cupin domain AcetylCoA_hydro PF02550.10 EMC96516.1 - 1.5e-50 171.6 0.0 2.3e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EMC96516.1 - 4.9e-41 139.9 0.0 8.3e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1772 PF08592.6 EMC96517.1 - 7.7e-13 48.3 0.1 1.1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.13 EMC96518.1 - 1.3e-17 63.5 2.5 1.8e-17 63.0 1.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC96518.1 - 4.8e-07 29.5 16.0 9.9e-07 28.5 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMC96519.1 - 5.3e-13 49.2 0.0 1.1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC96519.1 - 2.7e-08 33.8 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC96519.1 - 9.3e-05 22.1 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 KR domain DUF503 PF04456.7 EMC96519.1 - 0.12 11.9 0.6 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF503) Chorismate_bind PF00425.13 EMC96520.1 - 4.2e-76 255.6 0.0 5.9e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EMC96520.1 - 2.6e-28 98.8 0.0 4.3e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EMC96520.1 - 1.3e-16 60.8 0.0 3.3e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EMC96520.1 - 1.2e-06 28.0 0.0 7.7e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 Longin PF13774.1 EMC96521.1 - 1.6e-23 82.0 0.5 2.7e-23 81.3 0.3 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EMC96521.1 - 1.8e-16 59.5 0.2 4.7e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 Synaptobrevin Sirohm_synth_C PF14823.1 EMC96521.1 - 0.023 13.9 1.2 1.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DUF4404 PF14357.1 EMC96521.1 - 0.051 13.9 1.7 1.1 9.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) ASXH PF13919.1 EMC96522.1 - 3.4e-15 56.0 0.7 4.3e-15 55.7 0.5 1.1 1 0 0 1 1 1 1 Asx homology domain Elong_Iki1 PF10483.4 EMC96523.1 - 4.3e-76 255.9 0.0 5e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Med6 PF04934.9 EMC96524.1 - 1.1e-25 89.7 0.0 1.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Fungal_trans PF04082.13 EMC96525.1 - 4.1e-10 38.9 0.0 9.5e-10 37.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.26 EMC96526.1 - 1.7e-06 27.9 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF1981 PF09324.5 EMC96526.1 - 0.093 12.2 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) RF-1 PF00472.15 EMC96528.1 - 6.2e-27 93.6 2.0 7.2e-27 93.4 1.4 1.0 1 0 0 1 1 1 1 RF-1 domain DUF4502 PF14950.1 EMC96528.1 - 0.064 12.4 3.0 0.08 12.0 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) DUF3317 PF11779.3 EMC96529.1 - 1.9e-15 56.0 1.2 1.9e-15 56.0 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3317) DUF4059 PF13268.1 EMC96529.1 - 0.033 14.3 1.0 0.037 14.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) PRA1 PF03208.14 EMC96529.1 - 0.11 11.8 1.2 0.11 11.8 0.8 1.0 1 0 0 1 1 1 0 PRA1 family protein CRT10 PF08728.5 EMC96530.1 - 1.2e-13 50.0 0.0 6.6e-09 34.3 0.0 2.5 3 0 0 3 3 3 2 CRT10 FlpD PF02662.11 EMC96532.1 - 0.023 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit NmrA PF05368.8 EMC96534.1 - 3.5e-30 104.9 0.0 4.8e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC96534.1 - 1.8e-06 28.1 0.1 5.5e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC96534.1 - 1.4e-05 24.6 0.1 0.0036 16.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC96534.1 - 0.013 14.1 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Med2 PF11214.3 EMC96537.1 - 0.0048 16.9 0.9 0.0067 16.4 0.6 1.2 1 0 0 1 1 1 1 Mediator complex subunit 2 DUF1640 PF07798.6 EMC96538.1 - 3.5e-14 53.2 4.4 6.2e-14 52.4 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Lzipper-MIP1 PF14389.1 EMC96538.1 - 0.036 14.1 1.6 0.081 13.0 1.1 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 vMSA PF00695.14 EMC96538.1 - 0.2 10.8 0.2 0.46 9.6 0.0 1.6 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus IncA PF04156.9 EMC96538.1 - 9.3 5.7 12.0 0.21 11.1 2.9 2.1 2 1 0 2 2 2 0 IncA protein HALZ PF02183.13 EMC96539.1 - 0.00027 20.5 1.8 0.0063 16.1 0.3 2.9 3 0 0 3 3 3 1 Homeobox associated leucine zipper Tho2 PF11262.3 EMC96539.1 - 0.0017 17.4 0.9 0.0019 17.3 0.6 1.0 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Rho_Binding PF08912.6 EMC96539.1 - 0.0089 16.3 0.4 0.013 15.7 0.3 1.4 1 1 0 1 1 1 1 Rho Binding Jnk-SapK_ap_N PF09744.4 EMC96539.1 - 0.034 14.1 1.6 0.038 13.9 1.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 GrpE PF01025.14 EMC96539.1 - 0.059 12.9 0.4 0.063 12.8 0.3 1.2 1 0 0 1 1 1 0 GrpE Tmemb_cc2 PF10267.4 EMC96539.1 - 0.071 11.6 0.1 0.078 11.5 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3552 PF12072.3 EMC96539.1 - 0.08 12.1 0.8 0.086 12.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HSP70 PF00012.15 EMC96540.1 - 2e-270 897.9 7.4 2.2e-270 897.7 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC96540.1 - 9.8e-17 60.5 0.1 7.8e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EMC96540.1 - 0.0016 17.6 0.1 0.021 13.9 0.0 2.3 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EMC96540.1 - 0.0031 17.1 0.0 0.0071 15.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMC96540.1 - 0.08 12.7 4.4 5.9 6.7 3.1 3.4 1 1 0 1 1 1 0 Cell division protein FtsA Enhancin PF03272.8 EMC96540.1 - 0.33 8.8 1.4 0.54 8.0 0.9 1.2 1 0 0 1 1 1 0 Viral enhancin protein DUF1843 PF08898.5 EMC96540.1 - 1.3 9.1 4.2 1.2 9.2 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Mso1_Sec1_bdg PF14475.1 EMC96541.1 - 1.8e-18 65.6 0.1 3.6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 FAD_binding_2 PF00890.19 EMC96542.1 - 6.9e-34 117.3 0.0 9.8e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC96542.1 - 0.00041 20.2 0.0 0.0085 15.9 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IF2_N PF04760.10 EMC96542.1 - 0.079 12.6 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region GIDA PF01134.17 EMC96542.1 - 0.09 11.6 0.0 7.3 5.3 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Sigma70_r3 PF04539.11 EMC96542.1 - 0.097 12.5 0.1 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 Sigma-70 region 3 NUMOD1 PF07453.8 EMC96542.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain 2-Hacid_dh_C PF02826.14 EMC96545.1 - 3.5e-49 166.3 0.0 6.9e-49 165.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC96545.1 - 4.4e-16 58.5 0.0 7.1e-16 57.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC96545.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrmE_N PF10396.4 EMC96546.1 - 3.8e-35 120.2 0.0 8.1e-35 119.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EMC96546.1 - 1.1e-19 70.6 0.1 3.6e-19 68.9 0.1 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EMC96546.1 - 4.7e-16 58.7 0.0 9.2e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC96546.1 - 1.7e-05 24.1 0.1 0.00014 21.1 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMC96546.1 - 1.9e-05 24.5 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EMC96546.1 - 0.00049 20.5 0.0 0.0031 18.0 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 EMC96546.1 - 0.0052 16.2 0.2 0.019 14.4 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EMC96546.1 - 0.0098 15.3 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMC96546.1 - 0.058 12.5 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_hydro_3_C PF01915.17 EMC96546.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain FH2 PF02181.18 EMC96547.1 - 3.6e-81 272.9 7.3 3.6e-81 272.9 5.1 2.1 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EMC96547.1 - 2.4e-65 219.4 0.1 9.5e-65 217.4 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EMC96547.1 - 1.7e-50 171.1 0.3 1.7e-50 171.1 0.2 3.9 3 1 1 4 4 4 1 Diaphanous FH3 Domain Hus1 PF04005.7 EMC96548.1 - 8.9e-98 326.8 0.0 1e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein F-box-like PF12937.2 EMC96549.1 - 0.015 15.0 0.2 0.015 15.0 0.1 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EMC96549.1 - 0.024 14.3 0.0 0.07 12.8 0.0 1.9 1 0 0 1 1 1 0 F-box domain Myc_N PF01056.13 EMC96549.1 - 1.6 7.8 11.6 0.97 8.5 4.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Ribosomal_60s PF00428.14 EMC96549.1 - 1.6 9.1 5.3 0.36 11.2 1.1 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAM176 PF14851.1 EMC96549.1 - 4.8 6.8 7.4 1.3 8.6 1.0 2.3 2 0 0 2 2 2 0 FAM176 family Mito_carr PF00153.22 EMC96550.1 - 7.1e-60 198.7 1.9 2.8e-18 65.3 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein HEAT_2 PF13646.1 EMC96551.1 - 8.9e-14 51.5 18.2 0.0067 16.6 0.0 8.1 6 2 2 8 8 8 4 HEAT repeats HEAT PF02985.17 EMC96551.1 - 1.5e-05 24.6 33.4 0.52 10.5 0.0 11.3 13 0 0 13 13 13 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EMC96551.1 - 0.00019 21.7 0.0 0.12 12.8 0.0 4.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EMC96551.1 - 1.1 9.2 7.4 0.99 9.3 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EMC96551.1 - 3.3 8.3 25.5 4.6 7.8 0.2 8.0 7 2 1 8 8 8 0 HEAT-like repeat EF-hand_4 PF12763.2 EMC96552.1 - 3.5e-38 129.5 0.0 8.6e-16 57.5 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EMC96552.1 - 3.5e-11 43.0 0.1 0.001 19.1 0.0 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EMC96552.1 - 1.3e-06 27.3 0.1 0.52 9.7 0.0 4.8 5 0 0 5 5 4 2 EF hand Macoilin PF09726.4 EMC96552.1 - 7.8e-05 21.1 14.7 7.8e-05 21.1 10.2 1.6 2 0 0 2 2 1 1 Transmembrane protein EF-hand_8 PF13833.1 EMC96552.1 - 0.0014 18.1 0.0 0.46 10.1 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain pair CENP-F_leu_zip PF10473.4 EMC96552.1 - 0.0058 16.4 9.7 0.0058 16.4 6.7 3.0 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 EMC96552.1 - 0.0082 14.4 19.9 0.012 13.9 13.8 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Cast PF10174.4 EMC96552.1 - 0.018 13.1 30.2 0.025 12.6 20.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 EMC96552.1 - 0.018 14.2 6.2 0.036 13.2 4.3 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein EF-hand_6 PF13405.1 EMC96552.1 - 0.023 14.5 0.3 20 5.3 0.0 4.1 4 0 0 4 4 4 0 EF-hand domain IncA PF04156.9 EMC96552.1 - 0.054 13.0 33.5 44 3.5 23.3 2.2 1 1 0 1 1 1 0 IncA protein MAD PF05557.8 EMC96552.1 - 0.077 11.0 26.8 0.11 10.5 18.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ADIP PF11559.3 EMC96552.1 - 0.27 11.1 30.9 0.36 10.7 11.9 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Bcr-Abl_Oligo PF09036.5 EMC96552.1 - 0.3 11.0 3.5 0.31 11.0 0.1 2.5 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Filament PF00038.16 EMC96552.1 - 0.31 10.4 29.0 0.24 10.8 7.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein CCDC144C PF14915.1 EMC96552.1 - 0.46 9.3 24.6 1 8.2 9.6 2.1 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Rab5-bind PF09311.6 EMC96552.1 - 0.98 9.2 39.2 0.073 12.9 15.4 2.6 2 1 1 3 3 2 0 Rabaptin-like protein DUF4047 PF13256.1 EMC96552.1 - 1.1 9.1 5.9 1.7 8.6 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) IFT57 PF10498.4 EMC96552.1 - 1.8 7.2 17.8 3.3 6.3 12.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.7 EMC96552.1 - 1.8 8.3 33.6 13 5.5 4.8 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EMC96552.1 - 2.2 7.4 27.2 3.8 6.6 6.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EMC96552.1 - 4.2 5.1 11.9 6.5 4.4 8.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 EMC96552.1 - 4.6 7.0 12.4 8.8 6.1 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EMC96552.1 - 6.6 5.0 19.5 19 3.5 13.0 1.5 1 1 0 1 1 1 0 AAA domain DUF919 PF06034.6 EMC96552.1 - 6.7 6.4 6.0 0.86 9.2 0.0 2.5 3 1 1 4 4 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) MFS_1 PF07690.11 EMC96554.1 - 1.3e-35 122.7 33.1 1.3e-35 122.7 23.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC96554.1 - 1.5e-12 46.8 13.3 1.5e-12 46.8 9.2 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter Pkinase PF00069.20 EMC96556.1 - 1.1e-54 185.3 0.0 1.6e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC96556.1 - 1.8e-28 99.3 0.0 3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC96556.1 - 3.9e-11 42.4 0.0 1.7e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC96556.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC96556.1 - 0.054 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family UCH PF00443.24 EMC96557.1 - 6.9e-34 117.1 0.0 1e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC96557.1 - 1.7e-20 73.6 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_3 PF00933.16 EMC96559.1 - 8.7e-89 297.4 0.0 1.3e-88 296.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMC96559.1 - 9.5e-50 169.2 0.7 1.8e-49 168.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMC96559.1 - 2.2e-14 53.1 0.0 4.6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Rhodanese PF00581.15 EMC96560.1 - 4.4e-21 75.3 0.0 5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain EIF_2_alpha PF07541.7 EMC96561.1 - 7.8e-38 128.7 0.0 1.5e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EMC96561.1 - 4.8e-13 49.0 0.7 9.6e-13 48.0 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Cellulase PF00150.13 EMC96562.1 - 2.8e-29 102.1 3.7 5e-29 101.3 2.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.8 EMC96563.1 - 8.9e-45 152.8 0.4 1.4e-44 152.2 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EMC96563.1 - 6.5e-15 54.8 0.0 1.4e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMC96563.1 - 7.6e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC96563.1 - 0.00019 20.7 0.2 0.00034 19.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMC96563.1 - 0.00024 21.0 0.4 0.00031 20.6 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMC96563.1 - 0.005 15.7 0.0 0.0073 15.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EMC96563.1 - 0.0053 16.3 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EMC96563.1 - 0.016 13.7 0.0 0.32 9.4 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EMC96563.1 - 0.063 12.6 0.0 3.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Putative esterase GNVR PF13807.1 EMC96564.1 - 0.019 14.7 0.0 0.062 13.0 0.0 1.9 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase UIM PF02809.15 EMC96564.1 - 1.7 8.3 14.4 1.1 8.9 0.6 3.1 3 0 0 3 3 3 0 Ubiquitin interaction motif MutL_C PF08676.6 EMC96566.1 - 3.4e-26 91.5 0.2 7.4e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EMC96566.1 - 3.9e-20 71.4 0.0 1.3e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EMC96566.1 - 3.4e-13 49.4 0.1 1.5e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMC96566.1 - 2.1e-11 43.5 0.1 5e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SWIRM PF04433.12 EMC96568.1 - 6.2e-13 48.6 0.1 4.4e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain Herpes_DNAp_acc PF04929.7 EMC96568.1 - 1.5 7.7 5.4 2.5 6.9 3.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PMT PF02366.13 EMC96569.1 - 4.1e-85 285.0 16.2 4.1e-85 285.0 11.2 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMC96569.1 - 8.3e-39 133.0 1.5 1.2e-38 132.5 1.0 1.2 1 0 0 1 1 1 1 MIR domain Atg8 PF02991.11 EMC96570.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMC96570.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2665 PF11654.3 EMC96571.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Ribosomal_S26e PF01283.14 EMC96571.1 - 0.11 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S26e Thioredoxin PF00085.15 EMC96573.1 - 6e-08 32.3 0.0 7.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMC96573.1 - 0.0013 18.7 0.0 0.1 12.6 0.0 2.3 1 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC96573.1 - 0.0038 17.3 0.0 0.085 13.0 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EMC96573.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.5 1 1 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.1 EMC96573.1 - 0.026 14.3 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin domain DUF836 PF05768.9 EMC96573.1 - 0.086 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 EMC96573.1 - 0.15 11.6 0.0 1.6 8.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin Peptidase_M8 PF01457.11 EMC96576.1 - 0.17 10.1 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin LSM14 PF12701.2 EMC96577.1 - 3.3e-32 110.1 0.0 3.8e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 EMC96577.1 - 7.3e-06 25.8 0.0 9.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 EMC96577.1 - 0.057 12.9 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 LSM domain Mucin PF01456.12 EMC96578.1 - 0.58 9.9 18.7 0.88 9.3 13.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Lamp PF01299.12 EMC96578.1 - 3 6.9 9.1 3.7 6.6 6.3 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) TALPID3 PF15324.1 EMC96578.1 - 5.7 4.1 10.3 7.3 3.7 7.2 1.2 1 0 0 1 1 1 0 Hedgehog signalling target SET PF00856.23 EMC96581.1 - 2.2e-21 76.8 0.3 2.2e-21 76.8 0.2 3.9 4 2 0 4 4 4 1 SET domain SRI PF08236.6 EMC96581.1 - 1.2e-14 53.9 9.1 4.3e-14 52.2 6.4 2.0 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EMC96581.1 - 1.2e-06 27.9 0.6 4.1e-06 26.1 0.4 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.21 EMC96581.1 - 7.7e-06 25.6 0.7 1.5e-05 24.7 0.5 1.5 1 0 0 1 1 1 1 WW domain Thioredox_DsbH PF03190.10 EMC96584.1 - 1.1e-68 230.0 0.0 1.9e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EMC96584.1 - 4.4e-10 39.4 0.1 1.4e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Glyco_hydro_88 PF07470.8 EMC96584.1 - 0.00082 18.5 0.2 2.8 6.8 0.0 3.7 2 1 2 4 4 4 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 EMC96584.1 - 0.00098 18.5 0.3 0.0048 16.3 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Thioredoxin_2 PF13098.1 EMC96584.1 - 0.0061 16.7 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Sigma70_r4_2 PF08281.7 EMC96584.1 - 0.029 13.8 0.0 0.093 12.2 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 p47_phox_C PF08944.6 EMC96585.1 - 1.9 8.7 5.3 3.5 7.8 3.7 1.6 1 1 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain CAP PF00188.21 EMC96586.1 - 1.9e-15 57.4 5.1 1.9e-15 57.4 3.5 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF605 PF04652.11 EMC96586.1 - 0.053 12.9 31.0 0.07 12.5 21.5 1.1 1 0 0 1 1 1 0 Vta1 like Mitofilin PF09731.4 EMC96586.1 - 1.3 7.5 12.1 1.6 7.2 8.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.8 EMC96586.1 - 5.4 6.8 21.1 7.7 6.2 14.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.1 EMC96586.1 - 7 4.8 14.4 9 4.5 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NIF PF03031.13 EMC96587.1 - 7.5e-23 80.9 0.2 1.1e-22 80.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNA_pol_Rpb2_6 PF00562.23 EMC96588.1 - 5.7e-117 390.7 0.1 8.1e-117 390.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMC96588.1 - 6.2e-48 162.4 0.1 9e-48 161.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMC96588.1 - 1e-28 100.0 0.0 2.2e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMC96588.1 - 4.2e-28 97.4 0.6 1.4e-27 95.7 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EMC96588.1 - 3.9e-22 77.8 1.3 5.6e-22 77.3 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EMC96588.1 - 1e-18 66.8 0.1 2e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EMC96588.1 - 3.9e-12 45.9 0.2 8.3e-12 44.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MdcE PF06833.6 EMC96589.1 - 0.062 12.4 0.1 0.07 12.3 0.1 1.0 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) PUF PF00806.14 EMC96590.1 - 4.1e-54 177.1 14.2 2.8e-09 35.9 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MgtE_N PF03448.12 EMC96590.1 - 0.85 9.9 0.0 0.85 9.9 0.0 2.4 3 0 0 3 3 3 0 MgtE intracellular N domain DUF3684 PF12449.3 EMC96591.1 - 0 1330.2 0.0 0 1329.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EMC96591.1 - 4.7e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 EMC96591.1 - 0.00077 19.3 0.9 0.05 13.4 0.1 2.5 2 0 0 2 2 2 1 WLM domain HATPase_c PF02518.21 EMC96591.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UbiD PF01977.11 EMC96591.1 - 0.054 11.9 0.5 2.4 6.5 0.0 2.6 3 0 0 3 3 3 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CAS_CSE1 PF03378.10 EMC96592.1 - 4.1e-159 529.5 0.0 8.1e-159 528.5 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EMC96592.1 - 5.2e-145 482.6 0.8 2.3e-144 480.5 1.3 1.6 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 EMC96592.1 - 1.4e-16 60.1 0.1 4.2e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMC96592.1 - 0.1 12.4 1.0 0.81 9.5 0.0 3.2 3 2 0 3 3 3 0 Exportin 1-like protein DUF382 PF04037.8 EMC96593.1 - 6.6e-60 200.5 0.3 6.6e-60 200.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EMC96593.1 - 1.2e-21 75.8 7.9 2.4e-21 74.8 5.5 1.6 1 0 0 1 1 1 1 PSP DUF3840 PF12944.2 EMC96593.1 - 0.051 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) Lge1 PF11488.3 EMC96595.1 - 0.0045 17.1 0.4 0.0051 16.9 0.3 1.1 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 DUF3106 PF11304.3 EMC96595.1 - 0.042 14.2 0.3 0.049 14.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) SURF6 PF04935.7 EMC96595.1 - 0.088 12.0 4.6 0.11 11.7 3.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 RabGAP-TBC PF00566.13 EMC96596.1 - 2.3e-31 108.9 0.0 3.5e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ACCA PF03255.9 EMC96596.1 - 0.015 14.8 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MMS1_N PF10433.4 EMC96597.1 - 9.6e-86 287.9 0.0 1.6e-85 287.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Avl9 PF09794.4 EMC96598.1 - 3.7e-134 446.9 0.0 4.8e-134 446.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EMC96598.1 - 4.5e-09 35.9 0.0 2.3e-07 30.4 0.0 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EMC96598.1 - 6.7e-09 35.4 0.1 0.0004 20.0 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis SBBP PF06739.6 EMC96598.1 - 0.047 13.4 1.9 0.056 13.2 0.2 1.9 2 0 0 2 2 2 0 Beta-propeller repeat Chorion_2 PF03964.10 EMC96598.1 - 0.86 10.1 6.5 0.75 10.3 2.9 2.0 2 0 0 2 2 2 0 Chorion family 2 ADK PF00406.17 EMC96599.1 - 2.8e-59 199.3 0.0 3.4e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMC96599.1 - 4.7e-15 54.9 0.0 1.2e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EMC96599.1 - 1.2e-07 32.5 0.0 1.8e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC96599.1 - 0.00017 21.4 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC96599.1 - 0.00046 20.4 0.0 0.00091 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC96599.1 - 0.0084 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Alpha-amylase_C PF02806.13 EMC96601.1 - 5.2e-25 87.4 0.1 1.1e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EMC96601.1 - 1.8e-16 60.4 0.2 4.9e-13 49.1 0.2 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EMC96601.1 - 3.7e-14 52.5 0.1 1.1e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AAA_2 PF07724.9 EMC96602.1 - 9.3e-41 139.5 0.0 1.4e-39 135.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EMC96602.1 - 4.9e-15 55.8 0.0 8.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EMC96602.1 - 1.5e-07 31.2 0.0 3.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EMC96602.1 - 2.1e-07 30.7 0.0 7.3e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC96602.1 - 0.00022 21.2 0.7 0.00068 19.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC96602.1 - 0.00022 21.3 0.1 0.0041 17.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMC96602.1 - 0.00032 19.9 0.5 0.012 14.7 0.1 2.8 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMC96602.1 - 0.00065 20.5 0.5 0.0015 19.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EMC96602.1 - 0.00094 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 EMC96602.1 - 0.0012 18.4 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EMC96602.1 - 0.0061 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC96602.1 - 0.007 15.7 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC96602.1 - 0.0091 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 EMC96602.1 - 0.011 14.5 0.1 0.022 13.5 0.1 1.4 1 0 0 1 1 1 0 MCM2/3/5 family RuvB_N PF05496.7 EMC96602.1 - 0.023 13.7 0.0 0.079 11.9 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EMC96602.1 - 0.042 13.4 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMC96602.1 - 0.048 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EMC96602.1 - 0.075 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EMC96602.1 - 0.28 11.4 1.8 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Aminotran_5 PF00266.14 EMC96603.1 - 2.2e-19 69.4 0.0 3.4e-19 68.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EMC96603.1 - 8.3e-05 21.6 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2034 PF10356.4 EMC96604.1 - 8.2e-25 87.0 0.0 9.1e-12 44.5 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EMC96604.1 - 3.2e-09 36.5 0.0 4.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 EMC96605.1 - 1.1e-38 132.4 12.6 1.9e-38 131.6 8.7 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.5 EMC96605.1 - 1.6e-05 24.7 0.1 2.5e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Orbi_VP5 PF00901.12 EMC96605.1 - 0.26 9.4 2.0 0.34 9.0 1.4 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 SlyX PF04102.7 EMC96605.1 - 1.8 8.9 8.7 11 6.5 0.2 3.8 2 1 1 3 3 3 0 SlyX TFIIA PF03153.8 EMC96605.1 - 3.7 7.3 6.5 4.4 7.0 4.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DnaG_DnaB_bind PF08278.6 EMC96606.1 - 0.059 13.5 2.2 19 5.4 0.1 3.0 2 1 1 3 3 3 0 DNA primase DnaG DnaB-binding FtsQ PF03799.10 EMC96606.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsQ TPR_11 PF13414.1 EMC96607.1 - 8.1e-21 73.4 18.8 4.8e-11 42.1 1.9 3.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EMC96607.1 - 5.7e-10 38.3 11.4 7e-05 22.2 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC96607.1 - 2.9e-08 32.9 0.8 0.016 14.9 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC96607.1 - 1.4e-07 31.3 13.8 0.0011 18.8 2.6 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC96607.1 - 2.8e-07 30.1 2.5 0.049 13.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC96607.1 - 6.7e-07 28.7 25.1 9e-05 22.0 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC96607.1 - 3e-05 24.2 26.4 0.00021 21.6 0.2 6.6 4 1 3 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC96607.1 - 0.00017 21.8 12.0 0.035 14.4 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC96607.1 - 0.00018 22.1 2.5 0.00018 22.1 1.7 4.5 4 1 2 6 6 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMC96607.1 - 0.0013 18.5 1.1 0.0013 18.5 0.7 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC96607.1 - 0.019 15.0 3.5 0.046 13.8 0.6 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMC96607.1 - 0.13 12.1 15.0 0.48 10.3 0.1 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF751 PF05421.6 EMC96608.1 - 0.088 13.1 7.2 0.15 12.3 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF751) WhiA_N PF10298.4 EMC96609.1 - 0.098 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain 2-oxoacid_dh PF00198.18 EMC96610.1 - 5.9e-75 251.4 0.4 7.2e-75 251.2 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMC96610.1 - 1.4e-16 59.8 0.4 3.2e-16 58.7 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme PAT1 PF09770.4 EMC96610.1 - 1.4 7.0 5.2 1.8 6.6 3.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec7 PF01369.15 EMC96611.1 - 1e-65 220.9 0.8 1e-65 220.9 0.6 2.1 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EMC96611.1 - 5.5e-47 159.3 0.6 3.1e-46 156.8 0.0 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EMC96611.1 - 1e-30 105.0 1.2 7e-30 102.4 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Vasculin PF15337.1 EMC96613.1 - 0.059 13.8 0.4 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 Vascular protein family Vasculin-like 1 Methyltransf_31 PF13847.1 EMC96614.1 - 3.1e-12 46.3 0.0 2.5e-11 43.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC96614.1 - 1.6e-10 41.5 0.0 3.7e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC96614.1 - 2.3e-10 40.7 0.3 1.6e-07 31.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.9 EMC96614.1 - 6.4e-07 28.8 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EMC96614.1 - 2.1e-06 28.1 0.0 3.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC96614.1 - 8.4e-06 26.0 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC96614.1 - 2e-05 23.8 0.0 5.7e-05 22.3 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EMC96614.1 - 3.1e-05 23.1 0.0 4.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EMC96614.1 - 3.4e-05 23.8 1.2 5.7e-05 23.1 0.7 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC96614.1 - 8.1e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EMC96614.1 - 0.00032 20.4 0.0 0.0022 17.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMC96614.1 - 0.00068 19.3 0.0 0.0012 18.5 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 EMC96614.1 - 0.0029 16.7 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EMC96614.1 - 0.01 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 EMC96614.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.14 EMC96614.1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.6 2 0 0 2 2 1 0 FtsJ-like methyltransferase FmrO PF07091.6 EMC96614.1 - 0.025 13.5 0.0 0.12 11.3 0.0 2.0 3 0 0 3 3 3 0 Ribosomal RNA methyltransferase (FmrO) tRNA_U5-meth_tr PF05958.6 EMC96614.1 - 0.1 11.3 0.0 0.23 10.1 0.0 1.6 2 1 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.15 EMC96614.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SKN1 PF03935.10 EMC96615.1 - 1.4e-218 726.0 9.6 1.7e-218 725.8 6.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) MFS_1 PF07690.11 EMC96617.1 - 1.3e-39 135.9 43.8 1.3e-39 135.9 30.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EMC96617.1 - 0.0011 17.1 0.7 0.0011 17.1 0.5 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 EMC96618.1 - 1e-14 54.0 0.2 1.7e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC96618.1 - 1.5e-07 31.2 12.8 1.5e-07 31.2 8.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2540 PF10802.3 EMC96618.1 - 0.17 11.6 0.5 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) RseC_MucC PF04246.7 EMC96618.1 - 4.1 6.9 5.7 5.1 6.6 2.4 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ABC_membrane PF00664.18 EMC96619.1 - 2e-71 240.6 35.4 1.2e-38 133.1 9.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC96619.1 - 8.9e-64 213.8 0.0 5.1e-31 107.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC96619.1 - 8.6e-13 48.0 0.0 0.0003 20.1 0.0 4.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC96619.1 - 2.6e-11 43.8 0.5 2.2e-05 24.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EMC96619.1 - 1.6e-09 38.1 0.0 0.066 13.1 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EMC96619.1 - 1.5e-07 30.8 0.3 0.005 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMC96619.1 - 1.5e-07 30.7 0.0 0.01 15.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC96619.1 - 1.2e-06 29.3 0.0 0.025 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC96619.1 - 1.8e-06 28.1 0.7 0.21 11.7 0.1 3.9 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EMC96619.1 - 2.1e-06 26.6 0.9 0.0022 16.6 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 EMC96619.1 - 1.5e-05 24.5 1.2 0.18 11.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMC96619.1 - 2e-05 24.4 0.0 0.17 11.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EMC96619.1 - 4.7e-05 23.1 0.0 0.5 10.0 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA PF00004.24 EMC96619.1 - 0.00013 22.1 3.3 2 8.6 0.2 4.7 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EMC96619.1 - 0.00019 21.2 0.4 0.19 11.6 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EMC96619.1 - 0.00021 20.4 0.0 0.022 13.8 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.1 EMC96619.1 - 0.00031 20.6 0.0 1.1 9.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.10 EMC96619.1 - 0.00099 17.8 0.3 0.78 8.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EMC96619.1 - 0.0027 17.8 0.0 3.4 7.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.1 EMC96619.1 - 0.0032 17.8 1.0 2 8.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EMC96619.1 - 0.0034 16.8 0.1 2.9 7.2 0.0 3.1 3 1 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 EMC96619.1 - 0.017 15.1 0.0 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMC96619.1 - 0.02 15.1 0.0 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EMC96619.1 - 0.049 13.1 0.1 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EMC96619.1 - 0.05 12.2 4.3 1.6 7.3 0.0 2.8 3 0 0 3 3 2 0 G-protein alpha subunit DUF87 PF01935.12 EMC96619.1 - 0.1 12.3 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 V-SNARE_C PF12352.3 EMC96620.1 - 1.2e-14 54.1 0.2 2.9e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMC96620.1 - 0.00063 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.11 EMC96620.1 - 0.046 13.0 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 SnoaL_4 PF13577.1 EMC96621.1 - 5e-14 52.3 0.1 7.6e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain ASL_C2 PF14698.1 EMC96621.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal RPE65 PF03055.10 EMC96623.1 - 1.5e-129 432.7 0.0 1.7e-129 432.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein adh_short PF00106.20 EMC96624.1 - 2.9e-17 63.0 0.2 1.8e-07 31.2 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMC96624.1 - 2e-06 27.6 0.6 9e-05 22.2 0.4 2.3 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EMC96624.1 - 0.0014 18.7 0.0 0.12 12.4 0.0 2.6 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EMC96624.1 - 0.0019 17.9 0.3 0.0044 16.7 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EMC96624.1 - 0.0065 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF663 PF04950.7 EMC96625.1 - 3.7e-91 305.1 0.0 7.1e-91 304.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMC96625.1 - 8.3e-26 89.3 0.0 3.1e-25 87.5 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EMC96625.1 - 2.3e-07 30.4 0.0 5.4e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMC96625.1 - 8.9e-06 25.8 0.0 2.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC96625.1 - 4.3e-05 23.5 0.3 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMC96625.1 - 0.00011 23.0 0.0 0.00011 23.0 0.0 4.2 3 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EMC96625.1 - 0.00029 20.7 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EMC96625.1 - 0.00052 19.7 0.3 0.0013 18.4 0.2 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EMC96625.1 - 0.00086 19.7 0.0 0.0036 17.7 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA PF00004.24 EMC96625.1 - 0.0011 19.1 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EMC96625.1 - 0.0036 17.5 1.3 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.17 EMC96625.1 - 0.0042 15.9 0.2 0.0092 14.8 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 EMC96625.1 - 0.0062 16.4 0.0 0.0062 16.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EMC96625.1 - 0.0077 15.9 1.7 0.0093 15.6 0.2 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 EMC96625.1 - 0.0083 16.4 0.0 0.0083 16.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EMC96625.1 - 0.014 15.1 0.4 0.032 13.9 0.3 1.6 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 EMC96625.1 - 0.022 13.5 0.0 0.022 13.5 0.0 1.9 2 0 0 2 2 1 0 ArgK protein cobW PF02492.14 EMC96625.1 - 0.024 14.0 0.1 0.048 13.0 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EMC96625.1 - 0.027 14.0 0.3 0.072 12.6 0.2 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC96625.1 - 0.031 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EMC96625.1 - 0.032 14.1 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EMC96625.1 - 0.038 13.1 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EMC96625.1 - 0.043 13.9 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.4 EMC96625.1 - 0.076 12.4 0.0 1 8.8 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EMC96625.1 - 0.096 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 EMC96625.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.1 EMC96625.1 - 0.13 11.6 2.3 0.17 11.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain Inhibitor_I9 PF05922.11 EMC96626.1 - 4.6e-06 27.0 0.1 5.6e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 EMC96626.1 - 0.045 12.8 0.3 0.045 12.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) MCM PF00493.18 EMC96627.1 - 2.4e-127 424.3 0.2 3.6e-127 423.7 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMC96627.1 - 4.1e-16 59.5 0.0 9.5e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMC96627.1 - 1.3e-06 27.7 0.0 1.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMC96627.1 - 0.0042 16.6 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF605 PF04652.11 EMC96627.1 - 0.048 13.0 4.1 0.072 12.4 2.9 1.2 1 0 0 1 1 1 0 Vta1 like AAA_5 PF07728.9 EMC96627.1 - 0.072 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EMC96627.1 - 0.082 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Ribosomal_L1 PF00687.16 EMC96628.1 - 1.3e-59 201.2 0.1 1.6e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Whi5 PF08528.6 EMC96630.1 - 9.3e-07 28.3 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Whi5 like BCDHK_Adom3 PF10436.4 EMC96632.1 - 1.6e-40 138.2 0.0 2.4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMC96632.1 - 2.5e-14 52.9 0.6 1.3e-12 47.4 0.4 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMC96632.1 - 0.0048 16.5 0.3 0.061 12.9 0.2 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mt_ATP-synt_B PF05405.9 EMC96632.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) dsrm PF00035.20 EMC96633.1 - 1.5e-07 31.8 0.0 3.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EMC96633.1 - 2.8e-05 24.5 0.0 0.00052 20.4 0.0 2.7 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMC96633.1 - 7.3e-05 22.7 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like NmrA PF05368.8 EMC96635.1 - 4.1e-18 65.4 0.0 5e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC96635.1 - 2.2e-08 34.3 0.0 4.6e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 EMC96636.1 - 5.1e-44 149.5 0.0 8.6e-44 148.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMC96636.1 - 1.9e-40 138.4 0.0 3.2e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EMC96636.1 - 0.0044 15.7 0.0 0.0061 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMC96636.1 - 0.036 14.3 0.4 0.099 12.9 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 EMC96636.1 - 0.05 12.9 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Carn_acyltransf PF00755.15 EMC96637.1 - 3.6e-175 583.4 0.3 4.2e-175 583.2 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2683 PF10884.3 EMC96637.1 - 0.053 13.4 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) RTA1 PF04479.8 EMC96638.1 - 1e-20 74.2 4.5 2e-20 73.2 3.1 1.4 1 0 0 1 1 1 1 RTA1 like protein Mob1_phocein PF03637.12 EMC96641.1 - 2.1e-69 232.6 0.0 2.9e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family ATE_C PF04377.10 EMC96642.1 - 1.5e-43 147.9 3.4 1.5e-43 147.9 2.3 1.5 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EMC96642.1 - 5.3e-21 74.2 2.2 1.1e-20 73.2 1.0 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus NUDIX PF00293.23 EMC96644.1 - 3e-15 56.0 2.0 3.6e-15 55.8 1.4 1.1 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 EMC96647.1 - 1.9e-63 214.0 0.0 2.7e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC96647.1 - 2.5e-46 157.8 0.0 4.1e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EMC96647.1 - 2.5e-25 88.4 0.4 9.8e-25 86.5 0.0 2.3 3 0 0 3 3 3 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EMC96647.1 - 1.1e-16 60.4 0.0 2.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC96647.1 - 1.2e-16 60.6 0.0 2.5e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EMC96647.1 - 2.8e-07 29.7 0.0 0.0001 21.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EMC96647.1 - 0.0037 17.7 0.1 0.008 16.6 0.0 1.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Seadorna_VP7 PF07387.6 EMC96647.1 - 0.055 12.2 0.0 0.13 11.0 0.0 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 GMC_oxred_N PF00732.14 EMC96648.1 - 1e-61 208.6 0.0 1.4e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC96648.1 - 3.7e-24 85.6 0.0 7.6e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMC96648.1 - 5.7e-08 32.0 0.1 0.003 16.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC96648.1 - 5.4e-06 26.6 0.0 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC96648.1 - 6.6e-06 25.2 0.5 0.011 14.6 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 EMC96648.1 - 6.3e-05 22.9 0.0 0.022 14.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC96648.1 - 0.0042 17.0 0.1 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMC96648.1 - 0.007 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EMC96648.1 - 0.036 12.5 0.1 0.21 10.0 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EMC96648.1 - 0.084 11.9 0.3 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 EMC96648.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMC96648.1 - 0.12 11.2 0.1 8.1 5.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 EMC96648.1 - 0.14 12.1 0.1 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain WD40 PF00400.27 EMC96649.1 - 8.5e-14 50.8 2.2 1.2e-06 28.2 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat PPTA PF01239.17 EMC96651.1 - 4e-38 127.1 10.3 1.9e-07 30.1 0.7 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Con-6 PF10346.4 EMC96651.1 - 0.033 13.6 1.0 0.069 12.5 0.7 1.6 1 0 0 1 1 1 0 Conidiation protein 6 Pribosyl_synth PF14572.1 EMC96652.1 - 1.3e-45 155.3 0.5 3.6e-39 134.4 0.4 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EMC96652.1 - 1e-37 128.3 0.8 4.5e-37 126.3 0.0 2.4 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EMC96652.1 - 8.6e-11 41.6 0.4 2.2e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMC96652.1 - 0.00038 19.7 0.1 0.00058 19.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.14 EMC96653.1 - 1.5e-63 212.1 0.3 3.1e-63 211.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e MFS_1 PF07690.11 EMC96654.1 - 6.2e-36 123.8 31.4 6.2e-36 123.8 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.16 EMC96655.1 - 2.1e-99 333.0 39.6 2.4e-99 332.8 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMC96655.1 - 7.6e-25 87.3 44.8 1e-24 86.8 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EMC96655.1 - 0.68 9.6 8.4 0.82 9.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) p450 PF00067.17 EMC96656.1 - 2.1e-64 217.7 0.0 2.5e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EMC96657.1 - 1.3e-23 82.9 0.5 2.6e-23 81.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC96657.1 - 6.3e-09 36.7 0.2 2.5e-08 34.8 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC96657.1 - 1.7e-05 24.5 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EMC96657.1 - 0.069 13.1 0.3 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal KH_1 PF00013.24 EMC96659.1 - 8e-27 92.6 4.5 1e-07 31.4 0.2 7.0 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 EMC96659.1 - 1.6e-21 75.5 8.7 0.00019 21.0 0.0 6.4 6 0 0 6 6 6 4 KH domain CLASP_N PF12348.3 EMC96660.1 - 5.6e-111 369.3 1.3 6.3e-77 257.9 0.0 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EMC96660.1 - 6.9e-06 25.7 2.1 0.12 12.4 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EMC96660.1 - 0.38 11.0 24.0 0.091 13.0 0.2 4.8 2 2 1 3 3 3 0 HEAT repeats BSP PF04450.7 EMC96661.1 - 2.4e-67 226.3 0.0 2.7e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EMC96661.1 - 8.2e-06 25.8 0.1 2.6e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EMC96661.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 SprT-like family HAD_2 PF13419.1 EMC96663.1 - 2.2e-34 119.2 0.3 2.7e-34 118.9 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC96663.1 - 6.5e-08 32.1 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMC96663.1 - 4.7e-07 30.4 0.0 2e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RhoGAP PF00620.22 EMC96665.1 - 3.4e-47 159.8 0.0 1.1e-46 158.1 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EMC96665.1 - 1.7e-13 50.3 12.5 2.1e-07 30.9 0.1 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 EMC96665.1 - 0.21 11.5 13.9 0.41 10.6 1.0 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Seryl_tRNA_N PF02403.17 EMC96665.1 - 0.23 11.4 12.3 0.9 9.5 0.2 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 EMC96665.1 - 0.81 8.5 12.1 0.036 13.0 2.8 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Desulfoferrod_N PF06397.7 EMC96665.1 - 2 7.8 6.5 11 5.5 0.6 2.6 1 1 1 2 2 2 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_2 PF13240.1 EMC96665.1 - 3.4 7.2 9.5 3.1 7.4 0.0 4.1 4 1 0 4 4 4 0 zinc-ribbon domain GAS PF13851.1 EMC96665.1 - 4.6 6.3 18.1 8.6 5.5 12.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DASH_Ask1 PF08655.5 EMC96666.1 - 3.5e-33 113.2 0.1 5.8e-33 112.5 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 adh_short PF00106.20 EMC96667.1 - 8.8e-30 103.8 0.1 1.2e-29 103.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC96667.1 - 4.4e-19 69.2 0.2 5.1e-19 68.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC96667.1 - 5.3e-10 39.2 0.1 8.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC96667.1 - 0.0013 18.1 0.5 0.0069 15.8 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC96667.1 - 0.0019 16.9 1.2 0.0025 16.5 0.8 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HHH_5 PF14520.1 EMC96667.1 - 0.0037 17.3 1.4 0.4 10.8 0.4 3.5 2 1 1 3 3 3 1 Helix-hairpin-helix domain NanE PF04131.9 EMC96667.1 - 0.0066 15.4 0.3 1.5 7.7 0.1 2.2 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase Polysacc_synt_2 PF02719.10 EMC96667.1 - 0.0086 15.0 0.5 0.012 14.4 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FtsA PF14450.1 EMC96667.1 - 0.044 13.6 0.3 0.084 12.7 0.2 1.4 1 0 0 1 1 1 0 Cell division protein FtsA THF_DHG_CYH_C PF02882.14 EMC96667.1 - 0.085 11.9 0.2 0.36 9.8 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1482 PF07358.6 EMC96667.1 - 1.3 8.6 3.4 0.72 9.4 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1482) Myb_DNA-binding PF00249.26 EMC96669.1 - 2.8e-23 81.7 0.6 1.2e-12 47.6 0.1 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC96669.1 - 4.4e-17 61.9 1.4 1.3e-11 44.3 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 EMC96669.1 - 0.075 13.0 0.0 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Glyco_transf_41 PF13844.1 EMC96670.1 - 3e-98 328.8 0.0 7.2e-50 169.3 0.0 2.9 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EMC96670.1 - 7.6e-24 83.1 10.8 7.8e-09 35.0 0.0 4.7 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 EMC96670.1 - 2.8e-17 61.1 6.9 0.00012 21.7 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMC96670.1 - 3.3e-17 61.2 5.2 8.6e-05 21.9 0.0 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC96670.1 - 9e-14 50.7 5.6 0.013 16.0 0.0 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC96670.1 - 1.8e-13 49.2 0.2 0.0041 16.8 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC96670.1 - 2.3e-13 49.2 7.8 0.004 17.2 0.0 5.3 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMC96670.1 - 3.5e-12 46.0 8.7 2.3e-06 27.4 0.3 4.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC96670.1 - 9e-12 45.1 4.8 3.9e-07 30.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC96670.1 - 5.9e-11 42.7 7.2 8.1e-05 23.1 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC96670.1 - 4.8e-10 38.4 1.8 0.015 15.0 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMC96670.1 - 4.1e-08 32.8 8.3 0.24 11.3 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 EMC96670.1 - 4.3e-05 22.7 0.9 0.011 14.8 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC96670.1 - 0.00024 21.3 2.4 2.8 8.5 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC96670.1 - 0.00026 21.0 2.5 0.0081 16.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EMC96670.1 - 0.00031 21.0 1.4 0.24 11.6 0.0 2.9 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_9 PF13371.1 EMC96670.1 - 0.00064 19.5 3.9 1.7 8.5 0.3 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_5 PF12688.2 EMC96670.1 - 0.012 15.6 0.3 0.074 13.0 0.1 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat MIT PF04212.13 EMC96670.1 - 0.017 15.0 1.3 6 6.8 0.1 3.4 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EMC96670.1 - 0.052 14.2 4.1 0.22 12.2 0.5 3.4 3 0 0 3 3 3 0 Sel1 repeat Pyridox_oxidase PF01243.15 EMC96671.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HD PF01966.17 EMC96672.1 - 1.8e-05 24.7 2.0 2.1e-05 24.5 0.6 1.7 2 0 0 2 2 2 1 HD domain Cdd1 PF11731.3 EMC96672.1 - 0.17 11.8 2.1 0.22 11.4 0.2 2.1 2 0 0 2 2 2 0 Pathogenicity locus MitMem_reg PF13012.1 EMC96673.1 - 1.3e-38 131.5 0.2 1.3e-38 131.5 0.2 2.3 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EMC96673.1 - 1.5e-28 98.7 1.9 7.3e-28 96.6 0.0 2.4 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mak10 PF04112.8 EMC96673.1 - 0.039 13.1 0.2 0.07 12.3 0.2 1.3 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF1682 PF07946.9 EMC96673.1 - 1.8 7.3 16.6 3 6.6 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDHD PF02862.12 EMC96673.1 - 6.5 6.4 7.7 10 5.8 5.3 1.3 1 0 0 1 1 1 0 DDHD domain SWIM PF04434.12 EMC96674.1 - 0.00012 21.4 0.9 0.022 14.2 0.1 2.3 2 0 0 2 2 2 2 SWIM zinc finger ETF PF01012.16 EMC96675.1 - 1.4e-40 138.6 0.5 4.2e-40 137.1 0.1 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EMC96675.1 - 1.2e-34 117.8 0.0 2.4e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Spore_III_AF PF09581.5 EMC96677.1 - 0.023 14.5 3.4 0.04 13.7 2.4 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Lipoprotein_20 PF13942.1 EMC96677.1 - 0.034 13.6 3.3 0.049 13.1 2.3 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Fmp27_WPPW PF10359.4 EMC96677.1 - 0.056 11.8 2.3 0.071 11.5 1.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3829 PF12889.2 EMC96677.1 - 0.22 10.6 4.5 0.3 10.2 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Tnp_P_element PF12017.3 EMC96677.1 - 4 6.5 5.9 6.3 5.9 4.1 1.2 1 0 0 1 1 1 0 Transposase protein GFA PF04828.9 EMC96679.1 - 8.4e-13 48.0 0.2 1.1e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ABC_tran PF00005.22 EMC96681.1 - 6.6e-49 165.7 0.4 9.3e-24 84.2 0.0 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC96681.1 - 7.6e-18 64.5 0.2 7.6e-07 28.5 0.1 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC96681.1 - 1.7e-17 64.3 0.2 0.0021 18.0 0.1 4.4 3 1 1 4 4 4 4 AAA domain AAA_23 PF13476.1 EMC96681.1 - 2.8e-10 40.8 7.8 0.00017 21.9 2.5 4.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMC96681.1 - 1.6e-09 37.1 0.0 0.00095 18.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.1 EMC96681.1 - 9.3e-09 35.4 0.0 0.0073 16.5 0.1 3.6 1 1 3 4 4 4 3 HEAT repeats AAA_28 PF13521.1 EMC96681.1 - 1.8e-08 34.4 0.0 0.0086 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMC96681.1 - 8e-08 31.6 0.1 9.4e-05 21.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC96681.1 - 8.2e-08 33.1 0.0 0.0021 18.8 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC96681.1 - 1.1e-06 28.8 0.0 0.015 15.4 0.0 3.6 4 0 0 4 4 2 2 AAA domain PduV-EutP PF10662.4 EMC96681.1 - 1.7e-06 27.5 0.1 0.11 11.9 0.0 3.1 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EMC96681.1 - 6.5e-06 26.0 0.0 0.0089 15.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 EMC96681.1 - 8e-06 26.0 0.1 0.1 12.8 0.1 4.2 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMC96681.1 - 8.9e-06 25.3 0.3 0.26 10.6 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EMC96681.1 - 9.7e-06 25.4 0.0 0.045 13.6 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EMC96681.1 - 1.1e-05 25.9 0.0 0.033 14.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EMC96681.1 - 1.8e-05 25.0 0.2 0.19 12.0 0.0 3.7 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 EMC96681.1 - 3.9e-05 23.1 0.2 0.039 13.3 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EMC96681.1 - 4e-05 23.5 0.1 0.63 9.9 0.0 3.8 4 0 0 4 4 3 2 AAA domain ArgK PF03308.11 EMC96681.1 - 5.2e-05 22.1 0.1 0.03 13.0 0.0 2.5 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 EMC96681.1 - 7.1e-05 22.8 0.0 0.55 10.1 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain HEAT PF02985.17 EMC96681.1 - 8.7e-05 22.2 0.6 0.033 14.2 0.0 4.0 4 0 0 4 4 3 1 HEAT repeat AAA_33 PF13671.1 EMC96681.1 - 0.00015 21.6 0.0 0.92 9.3 0.0 3.3 4 0 0 4 4 2 2 AAA domain NACHT PF05729.7 EMC96681.1 - 0.00015 21.4 0.0 0.18 11.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EMC96681.1 - 0.00017 21.3 0.7 0.29 10.8 0.0 3.6 3 0 0 3 3 3 1 Archaeal ATPase MobB PF03205.9 EMC96681.1 - 0.00019 21.1 0.0 0.91 9.2 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EMC96681.1 - 0.00023 21.2 0.0 0.55 10.4 0.0 3.1 3 0 0 3 3 2 1 RNA helicase Dynamin_N PF00350.18 EMC96681.1 - 0.00026 20.8 0.0 0.029 14.2 0.0 3.1 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 EMC96681.1 - 0.00028 20.7 0.8 0.18 11.5 0.0 3.6 4 0 0 4 4 2 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EMC96681.1 - 0.00048 19.6 0.0 0.74 9.2 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EMC96681.1 - 0.00053 19.6 0.1 1.2 8.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain HEAT_EZ PF13513.1 EMC96681.1 - 0.00093 19.6 0.2 0.051 14.0 0.0 4.0 4 1 1 5 5 1 1 HEAT-like repeat AAA_15 PF13175.1 EMC96681.1 - 0.001 18.1 12.1 0.22 10.5 0.0 4.9 4 2 2 6 6 6 2 AAA ATPase domain AAA_13 PF13166.1 EMC96681.1 - 0.0011 17.6 8.5 0.46 8.8 0.0 4.5 5 1 0 6 6 5 2 AAA domain AAA_25 PF13481.1 EMC96681.1 - 0.002 17.5 0.0 2 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 EMC96681.1 - 0.0024 16.6 0.7 0.37 9.4 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit AAA_19 PF13245.1 EMC96681.1 - 0.0078 15.9 0.0 6.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 EMC96681.1 - 0.013 14.4 0.1 4.6 6.0 0.0 2.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EMC96681.1 - 0.013 14.3 0.2 0.2 10.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.12 EMC96681.1 - 0.013 15.0 0.0 6.2 6.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EMC96681.1 - 0.024 14.2 0.0 3.6 7.2 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EMC96681.1 - 0.033 13.3 0.0 2.8 7.0 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Arf PF00025.16 EMC96681.1 - 0.039 13.1 0.0 5.7 6.1 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 EMC96681.1 - 0.052 13.0 0.1 2.1 7.7 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 EMC96681.1 - 0.058 13.1 0.0 14 5.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EMC96681.1 - 0.063 12.6 0.0 12 5.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein MutS_V PF00488.16 EMC96681.1 - 0.11 11.8 0.2 11 5.2 0.0 2.3 2 0 0 2 2 2 0 MutS domain V Eaf7 PF07904.8 EMC96682.1 - 1.9e-20 72.6 1.5 2.4e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 Chromatin modification-related protein EAF7 Nucleoplasmin PF03066.10 EMC96682.1 - 2.1 7.8 10.5 3.2 7.2 7.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin Ion_trans PF00520.26 EMC96683.1 - 4.1e-06 26.1 21.7 0.00068 18.9 15.0 2.3 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 EMC96683.1 - 0.00015 20.3 13.1 0.0054 15.1 9.1 2.2 1 1 0 1 1 1 1 Polycystin cation channel Cupin_1 PF00190.17 EMC96684.1 - 7.7e-07 28.6 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EMC96684.1 - 1.2e-05 24.7 0.8 2.1e-05 23.9 0.5 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EMC96684.1 - 0.00074 19.1 0.1 0.00094 18.8 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EMC96684.1 - 0.034 13.8 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.9 EMC96684.1 - 0.06 13.2 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Sugar_tr PF00083.19 EMC96685.1 - 2e-87 293.6 36.6 2.5e-87 293.3 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96685.1 - 5.5e-20 71.3 62.3 3.1e-18 65.6 22.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 EMC96687.1 - 1.4e-43 149.0 0.3 1.6e-30 105.9 0.0 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family FAD_binding_8 PF08022.7 EMC96689.1 - 3e-16 59.1 0.0 6.3e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMC96689.1 - 8.4e-14 51.7 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMC96689.1 - 8.1e-12 45.3 14.7 8.1e-12 45.3 10.2 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Epimerase PF01370.16 EMC96690.1 - 3.1e-24 85.7 0.0 4.3e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC96690.1 - 2e-21 75.9 0.0 2.7e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMC96690.1 - 1.1e-15 58.1 0.1 3.8e-15 56.3 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMC96690.1 - 1.2e-11 44.0 0.0 1.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EMC96690.1 - 1.9e-07 30.6 0.0 3.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EMC96690.1 - 9.4e-06 25.6 0.8 8.1e-05 22.5 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMC96690.1 - 9.2e-05 21.4 0.0 0.00028 19.8 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EMC96690.1 - 0.00022 20.9 0.6 0.00092 18.9 0.4 1.9 1 1 0 1 1 1 1 KR domain Ctf8 PF09696.5 EMC96691.1 - 2.9e-31 107.7 0.0 3.7e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Ctf8 HLH PF00010.21 EMC96692.1 - 3.6e-05 23.3 0.3 5e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.1 EMC96692.1 - 0.057 13.9 0.1 0.057 13.8 0.0 1.1 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 MRP PF09387.5 EMC96692.1 - 0.1 12.3 0.3 0.1 12.3 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP AAA_27 PF13514.1 EMC96692.1 - 0.11 10.2 0.1 0.11 10.1 0.1 1.0 1 0 0 1 1 1 0 AAA domain Coprogen_oxidas PF01218.13 EMC96695.1 - 2.1e-135 450.0 0.1 3.1e-135 449.4 0.0 1.2 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Sugar_tr PF00083.19 EMC96695.1 - 6.2e-101 338.1 17.5 8.3e-101 337.7 12.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96695.1 - 1.6e-29 102.7 25.7 3.6e-29 101.6 13.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC96695.1 - 0.00035 20.3 0.0 0.00092 18.9 0.0 1.7 1 0 0 1 1 1 1 MFS_1 like family Tmemb_18A PF09771.4 EMC96695.1 - 5.1 7.0 7.7 1.3 9.0 0.2 2.8 3 0 0 3 3 3 0 Transmembrane protein 188 CDC50 PF03381.10 EMC96696.1 - 1.8e-89 299.5 0.0 2.3e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Peptidase_M43 PF05572.8 EMC96697.1 - 5.4e-13 48.8 0.1 1.3e-12 47.6 0.1 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EMC96697.1 - 4.1e-05 23.7 0.5 5.7e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC96697.1 - 0.00068 19.6 1.6 0.001 19.0 0.9 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 EMC96697.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 EMC96697.1 - 0.0087 16.5 0.3 0.016 15.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC96697.1 - 0.041 13.3 2.3 0.059 12.9 1.6 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3810 PF12725.2 EMC96697.1 - 0.1 11.4 0.2 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Lysine_decarbox PF03641.9 EMC96698.1 - 1.2e-30 106.0 0.0 1.7e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Ras PF00071.17 EMC96699.1 - 7.5e-49 165.2 0.2 7e-39 132.8 0.1 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EMC96699.1 - 3.2e-16 59.9 0.0 1.3e-15 57.9 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC96699.1 - 7.4e-12 44.8 0.0 2.9e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC96699.1 - 1.4e-07 31.1 0.0 7.1e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC96699.1 - 7e-06 25.3 2.1 4.7e-05 22.6 1.4 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC96699.1 - 0.0016 18.3 0.0 0.0054 16.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Resolvase PF00239.16 EMC96699.1 - 0.14 12.0 1.4 0.17 11.7 0.4 1.6 2 0 0 2 2 2 0 Resolvase, N terminal domain Dynamin_N PF00350.18 EMC96700.1 - 4.8e-11 42.7 0.0 1.5e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EMC96700.1 - 1.6e-06 28.0 0.0 0.025 14.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.11 EMC96700.1 - 0.017 14.2 1.4 0.23 10.5 0.3 2.4 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.13 EMC96700.1 - 0.11 11.7 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Takusan PF04822.8 EMC96700.1 - 0.39 10.5 5.3 3.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Takusan Chs3p PF12271.3 EMC96702.1 - 7.1e-92 307.5 6.2 8.6e-92 307.2 4.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Lysis_S PF04971.7 EMC96702.1 - 0.0015 18.1 0.5 0.0078 15.8 0.1 2.4 2 0 0 2 2 2 1 Lysis protein S YvrJ PF12841.2 EMC96702.1 - 0.042 13.1 0.1 0.083 12.1 0.1 1.4 1 0 0 1 1 1 0 YvrJ protein family Ssl1 PF04056.9 EMC96703.1 - 5.7e-74 247.8 0.0 7.5e-74 247.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EMC96703.1 - 1.7e-17 63.1 10.6 1.7e-17 63.1 7.4 3.2 3 2 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 EMC96703.1 - 9.4e-10 38.8 0.0 1.8e-09 37.9 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.9 EMC96703.1 - 0.0038 16.5 1.3 0.0057 15.9 0.9 1.4 1 0 0 1 1 1 1 Transcription factor Tfb4 HeLo PF14479.1 EMC96704.1 - 1.1e-19 71.0 0.1 1.6e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.2 EMC96705.1 - 6.5e-18 64.8 0.9 3.2e-10 40.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC96705.1 - 9e-16 56.8 5.4 2.6e-05 23.8 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EMC96705.1 - 2.8e-09 36.3 0.8 0.007 16.5 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EMC96705.1 - 1.1e-08 35.3 1.8 0.0018 18.7 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC96705.1 - 1.6e-08 34.4 1.9 0.008 16.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC96706.1 - 3.3e-37 124.4 11.6 1.3e-10 40.5 0.0 5.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EMC96706.1 - 1.7e-36 124.4 6.1 2.9e-20 72.3 1.7 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC96706.1 - 4.3e-32 109.9 2.4 1.2e-12 47.9 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC96706.1 - 2.8e-30 101.3 3.1 1.6e-06 27.8 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EMC96706.1 - 3.8e-28 96.8 13.0 7.6e-09 35.5 0.1 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) gag-asp_proteas PF13975.1 EMC96706.1 - 0.016 15.0 0.0 0.058 13.2 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4541 PF15074.1 EMC96706.1 - 0.022 15.2 0.0 0.069 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) RVP PF00077.15 EMC96706.1 - 0.12 12.2 0.3 0.62 10.0 0.0 2.2 2 1 1 3 3 3 0 Retroviral aspartyl protease Gp_dh_C PF02800.15 EMC96707.1 - 1.7e-73 245.2 0.0 2.3e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EMC96707.1 - 1.3e-59 200.5 0.1 2.2e-59 199.7 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EMC96707.1 - 0.0051 16.7 0.8 0.047 13.6 0.1 2.6 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EMC96707.1 - 0.013 14.9 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4440 PF14534.1 EMC96709.1 - 1.7e-06 28.2 0.0 2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) 4HBT_2 PF13279.1 EMC96710.1 - 3.3e-07 30.7 0.0 4.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Mito_carr PF00153.22 EMC96711.1 - 3.9e-31 106.6 7.0 2.5e-13 49.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EMC96712.1 - 3.9e-103 344.9 0.0 4.8e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EMC96712.1 - 0.048 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone RRM_5 PF13893.1 EMC96713.1 - 5.9e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC96713.1 - 0.00018 21.0 0.0 0.00042 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EMC96713.1 - 0.00056 20.0 0.0 0.0014 18.8 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_6 PF14259.1 EMC96713.1 - 0.0008 19.3 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CytochromB561_N PF09786.4 EMC96714.1 - 0.13 10.6 0.2 0.17 10.3 0.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF456 PF04306.8 EMC96714.1 - 0.51 10.3 4.1 0.14 12.2 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Peptidase_M1 PF01433.15 EMC96716.1 - 3.1e-135 451.2 0.9 4.9e-135 450.5 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMC96716.1 - 1.4e-79 267.7 0.1 2.3e-79 266.9 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMC96716.1 - 1.9e-21 76.4 3.5 2.5e-21 76.0 0.5 2.5 1 1 1 2 2 2 1 Peptidase MA superfamily BC10 PF06726.7 EMC96717.1 - 2e-10 40.5 7.8 3.4e-10 39.8 5.4 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF3394 PF11874.3 EMC96717.1 - 0.071 12.6 0.2 0.082 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) VKOR PF07884.9 EMC96717.1 - 3.9 7.3 7.9 6.9 6.5 5.5 1.4 1 0 0 1 1 1 0 Vitamin K epoxide reductase family DUF87 PF01935.12 EMC96718.1 - 0.00083 19.2 0.9 0.017 14.9 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EMC96718.1 - 0.0013 18.2 0.2 2.1 7.7 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain ABC_tran PF00005.22 EMC96718.1 - 0.0024 18.1 1.3 0.027 14.7 0.2 2.7 2 1 0 2 2 2 1 ABC transporter OmpH PF03938.9 EMC96718.1 - 0.023 14.6 0.7 0.082 12.8 0.5 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF258 PF03193.11 EMC96718.1 - 0.026 13.7 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMC96718.1 - 0.027 14.4 0.1 0.3 11.0 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EMC96718.1 - 0.062 13.2 0.1 0.92 9.4 0.1 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC96718.1 - 0.073 13.2 0.0 0.3 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC96718.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EMC96718.1 - 0.17 12.1 2.8 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 EMC96718.1 - 0.33 10.0 4.1 1.6 7.8 0.0 2.7 2 1 0 2 2 2 0 AIG1 family Ras PF00071.17 EMC96719.1 - 1.1e-62 210.1 0.2 1.3e-62 209.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC96719.1 - 6.3e-22 78.2 0.1 8.6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC96719.1 - 2.5e-13 49.6 0.1 3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC96719.1 - 1.8e-08 34.3 0.1 2.6e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC96719.1 - 4.3e-05 23.0 0.1 0.00014 21.3 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC96719.1 - 0.00012 21.2 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EMC96719.1 - 0.00015 21.9 0.1 0.00036 20.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC96719.1 - 0.0007 19.5 0.1 0.0015 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMC96719.1 - 0.0019 17.3 0.1 0.0033 16.6 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EMC96719.1 - 0.0029 16.8 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 EMC96719.1 - 0.0031 16.6 0.0 0.0037 16.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SpoIIID PF12116.3 EMC96719.1 - 0.005 16.7 0.1 0.061 13.2 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D ABC_tran PF00005.22 EMC96719.1 - 0.015 15.5 0.2 0.023 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EMC96719.1 - 0.016 15.2 0.3 0.034 14.1 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EMC96719.1 - 0.019 14.5 0.2 0.028 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF1128 PF06569.6 EMC96719.1 - 0.023 14.4 0.0 0.061 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) AAA_32 PF13654.1 EMC96719.1 - 0.056 12.1 0.1 0.42 9.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 EMC96719.1 - 0.068 12.4 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EMC96719.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EMC96719.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 EMC96720.1 - 4.3e-09 35.9 1.3 1.2e-08 34.5 0.2 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4508 PF14969.1 EMC96720.1 - 0.05 13.5 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) Metallophos PF00149.23 EMC96721.1 - 5.7e-39 133.5 0.0 8e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EMC96721.1 - 1.1e-27 95.9 0.8 1.1e-27 95.9 0.5 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 EMC96721.1 - 2.3e-05 23.9 0.8 2.3e-05 23.9 0.6 1.7 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMC96721.1 - 2.6e-05 23.6 0.8 0.06 12.9 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC96721.1 - 0.029 14.2 3.1 4.3 7.4 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Spt4 PF06093.8 EMC96722.1 - 4.3e-32 109.8 0.0 4.9e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Abi PF02517.11 EMC96724.1 - 6.1e-15 55.1 12.5 4.2e-14 52.4 6.8 2.7 2 1 0 2 2 2 1 CAAX protease self-immunity Mid1 PF12929.2 EMC96726.1 - 9.9e-134 446.2 2.1 1.2e-133 445.9 1.4 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Rep_fac_C PF08542.6 EMC96727.1 - 7.9e-22 77.0 0.0 1.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EMC96727.1 - 2.6e-12 46.7 0.0 2.4e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EMC96727.1 - 1.7e-11 44.4 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMC96727.1 - 7.3e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EMC96727.1 - 1.3e-06 27.4 0.0 0.016 13.8 0.0 2.6 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EMC96727.1 - 6.9e-06 26.1 0.0 0.00031 20.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 EMC96727.1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EMC96727.1 - 1.8e-05 24.8 0.0 0.019 15.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EMC96727.1 - 8e-05 21.7 0.0 0.0002 20.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EMC96727.1 - 0.00027 20.4 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 EMC96727.1 - 0.00037 20.1 0.0 0.001 18.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMC96727.1 - 0.0006 19.3 0.0 0.12 11.8 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 EMC96727.1 - 0.0014 17.7 0.0 0.019 14.1 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMC96727.1 - 0.002 17.8 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EMC96727.1 - 0.0055 16.1 0.1 0.27 10.6 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EMC96727.1 - 0.0083 15.7 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EMC96727.1 - 0.013 15.1 0.2 0.059 13.0 0.1 2.1 1 1 1 2 2 2 0 NTPase ArgK PF03308.11 EMC96727.1 - 0.015 14.0 0.0 0.039 12.7 0.0 1.5 1 1 1 2 2 2 0 ArgK protein DEAD PF00270.24 EMC96727.1 - 0.02 14.3 0.1 0.32 10.4 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.9 EMC96727.1 - 0.027 14.1 0.0 0.069 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_31 PF13614.1 EMC96727.1 - 0.044 13.7 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMC96727.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EMC96727.1 - 0.054 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EMC96727.1 - 0.071 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Glyco_hydro_47 PF01532.15 EMC96728.1 - 7.8e-165 548.9 0.0 9.1e-165 548.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Asp PF00026.18 EMC96730.1 - 1.3e-75 254.5 6.0 1.8e-75 254.1 4.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC96730.1 - 9.1e-09 35.4 0.8 2.1e-07 31.0 0.2 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMC96730.1 - 0.0003 21.2 0.7 1.1 9.7 0.1 3.6 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMC96730.1 - 0.01 15.3 0.0 0.068 12.7 0.0 2.5 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Macoilin PF09726.4 EMC96731.1 - 0.00032 19.1 12.3 0.00039 18.8 8.5 1.1 1 0 0 1 1 1 1 Transmembrane protein GAS PF13851.1 EMC96731.1 - 0.00051 19.2 10.1 0.00057 19.1 0.3 3.3 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding CCDC144C PF14915.1 EMC96731.1 - 0.0044 15.9 14.3 0.0074 15.2 7.8 2.1 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region TMF_DNA_bd PF12329.3 EMC96731.1 - 0.0047 16.7 16.7 0.024 14.4 0.6 4.1 3 1 1 4 4 4 1 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EMC96731.1 - 0.005 15.9 7.2 0.059 12.4 2.8 2.1 2 0 0 2 2 2 1 Autophagy protein Apg6 Herpes_U30 PF04523.8 EMC96731.1 - 0.0096 13.4 0.8 0.013 12.9 0.5 1.2 1 0 0 1 1 1 1 Herpes virus tegument protein U30 DUF641 PF04859.7 EMC96731.1 - 0.014 15.1 7.6 0.64 9.7 0.0 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.6 EMC96731.1 - 0.014 14.8 11.0 2 7.8 0.0 3.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 EMC96731.1 - 0.016 15.0 3.1 0.088 12.6 1.6 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_N PF10481.4 EMC96731.1 - 0.035 13.4 6.8 0.017 14.5 2.7 1.8 1 1 0 1 1 1 0 Cenp-F N-terminal domain Spectrin PF00435.16 EMC96731.1 - 0.036 14.3 7.4 0.43 10.8 2.9 3.2 2 1 1 3 3 3 0 Spectrin repeat PspA_IM30 PF04012.7 EMC96731.1 - 0.066 12.5 14.8 0.15 11.3 6.4 2.5 2 1 0 2 2 2 0 PspA/IM30 family Lzipper-MIP1 PF14389.1 EMC96731.1 - 0.11 12.5 8.2 0.61 10.2 0.1 3.4 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF4201 PF13870.1 EMC96731.1 - 0.17 11.2 14.9 1.1 8.6 1.6 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.3 EMC96731.1 - 0.17 11.5 10.5 0.86 9.3 3.5 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Cauli_AT PF03233.8 EMC96731.1 - 0.18 11.4 2.9 0.25 11.0 0.2 2.3 2 1 1 3 3 3 0 Aphid transmission protein Occludin_ELL PF07303.8 EMC96731.1 - 0.25 12.0 1.3 19 6.0 0.2 3.0 2 1 1 3 3 3 0 Occludin homology domain Cob_adeno_trans PF01923.13 EMC96731.1 - 0.31 10.8 3.3 0.65 9.7 1.0 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase IncA PF04156.9 EMC96731.1 - 0.33 10.5 16.4 29 4.2 11.4 2.7 1 1 0 1 1 1 0 IncA protein Sec2p PF06428.6 EMC96731.1 - 0.35 10.7 11.6 0.45 10.3 1.5 3.5 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p DivIC PF04977.10 EMC96731.1 - 0.83 9.1 14.8 7 6.2 1.5 4.2 3 1 1 4 4 4 0 Septum formation initiator Fez1 PF06818.10 EMC96731.1 - 1.5 8.8 13.7 0.19 11.7 5.3 2.2 1 1 1 2 2 2 0 Fez1 ADIP PF11559.3 EMC96731.1 - 2.5 8.0 16.4 0.75 9.6 0.7 3.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.19 EMC96731.1 - 2.7 7.6 5.0 0.44 10.2 0.5 2.0 2 1 1 3 3 2 0 emp24/gp25L/p24 family/GOLD Nup54 PF13874.1 EMC96731.1 - 3 7.5 7.8 0.99 9.0 1.2 2.7 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Val_tRNA-synt_C PF10458.4 EMC96731.1 - 4.2 7.5 7.2 29 4.8 0.1 3.6 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DivIVA PF05103.8 EMC96731.1 - 4.8 7.2 12.4 17 5.4 4.7 3.1 2 2 0 2 2 2 0 DivIVA protein DUF4140 PF13600.1 EMC96731.1 - 9.8 6.6 15.6 16 6.0 0.9 4.0 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) UPF0220 PF05255.6 EMC96732.1 - 5.2e-65 217.7 4.7 5.8e-65 217.5 3.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF46 PF01864.12 EMC96732.1 - 0.013 15.3 0.8 0.016 15.0 0.5 1.2 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 cwf21 PF08312.7 EMC96733.1 - 6.1e-18 64.3 7.9 1.7e-17 62.9 5.5 1.7 1 0 0 1 1 1 1 cwf21 domain MRP-L28 PF09812.4 EMC96733.1 - 0.013 15.3 1.1 0.013 15.3 0.7 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 Acetyltransf_7 PF13508.1 EMC96734.1 - 1.9e-07 31.1 0.0 5.7e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC96734.1 - 1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMC96734.1 - 0.00027 20.7 0.0 0.014 15.2 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC96734.1 - 0.0013 18.7 0.0 0.0067 16.5 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC96734.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3128 PF11326.3 EMC96735.1 - 2.7e-28 97.9 2.5 4.8e-28 97.1 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Metal_resist PF13801.1 EMC96735.1 - 0.53 10.2 3.0 0.25 11.3 0.5 1.6 2 0 0 2 2 2 0 Heavy-metal resistance DUF2011 PF09428.5 EMC96736.1 - 3e-24 85.3 8.4 4.1e-24 84.9 5.8 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) zf-RING_2 PF13639.1 EMC96738.1 - 1.4e-10 40.8 6.3 2.3e-10 40.1 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC96738.1 - 1.7e-08 34.0 4.7 2.7e-08 33.3 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC96738.1 - 1.1e-07 31.5 5.9 1.7e-07 30.8 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC96738.1 - 7.9e-07 29.0 5.5 1.4e-06 28.1 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC96738.1 - 1.7e-06 27.5 6.6 2.9e-06 26.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC96738.1 - 0.00013 21.6 1.4 0.0003 20.4 1.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMC96738.1 - 0.0016 18.4 3.5 0.0033 17.4 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EMC96738.1 - 0.016 14.7 8.8 0.034 13.7 6.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 EMC96738.1 - 0.1 12.3 6.6 0.29 10.8 4.5 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-Apc11 PF12861.2 EMC96738.1 - 0.26 11.1 5.3 0.78 9.6 3.7 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EMC96738.1 - 0.29 11.1 7.3 0.65 9.9 5.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn-ribbon_8 PF09723.5 EMC96738.1 - 0.51 10.3 6.8 0.69 9.9 2.5 2.3 2 0 0 2 2 2 0 Zinc ribbon domain RINGv PF12906.2 EMC96738.1 - 0.7 9.9 5.0 1.2 9.1 3.5 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.1 EMC96738.1 - 1.7 8.2 8.5 3 7.4 1.5 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EMC96738.1 - 6.9 6.2 9.8 31 4.1 6.8 2.2 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Cupin_2 PF07883.6 EMC96739.1 - 1.2e-07 31.1 0.1 2.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMC96739.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PCI PF01399.22 EMC96740.1 - 0.021 15.1 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 PCI domain AA_permease_2 PF13520.1 EMC96741.1 - 1.3e-65 221.6 42.0 4.2e-65 219.9 29.1 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC96741.1 - 8.9e-24 83.6 42.2 6.2e-23 80.8 29.3 1.9 1 1 0 1 1 1 1 Amino acid permease RFC1 PF08519.7 EMC96742.1 - 0.078 12.7 0.0 9.4 5.9 0.0 2.2 1 1 1 2 2 2 0 Replication factor RFC1 C terminal domain Attractin PF08037.6 EMC96743.1 - 0.099 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Attractin family DUF4141 PF13605.1 EMC96745.1 - 0.01 14.9 0.1 0.024 13.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Pga1 PF10333.4 EMC96745.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Tubulin PF00091.20 EMC96746.1 - 1.4e-69 234.1 0.0 2.1e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC96746.1 - 1.2e-48 164.2 0.1 2.1e-48 163.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC96746.1 - 0.0019 17.7 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain DUF1415 PF07209.7 EMC96746.1 - 0.06 13.0 0.1 4.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Lipase_3 PF01764.20 EMC96746.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) HET PF06985.6 EMC96747.1 - 2.3e-33 115.2 0.1 4.2e-33 114.4 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.21 EMC96750.1 - 3.4e-08 33.2 2.8 6.7e-08 32.2 2.0 1.5 1 0 0 1 1 1 1 WW domain Ras PF00071.17 EMC96751.1 - 2e-65 219.0 1.1 2.4e-65 218.8 0.8 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC96751.1 - 1e-21 77.6 0.0 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC96751.1 - 1.3e-16 60.3 0.2 1.6e-16 60.0 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC96751.1 - 1.4e-05 24.3 0.1 1.7e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC96751.1 - 2.5e-05 23.7 0.3 5.4e-05 22.7 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC96751.1 - 5.9e-05 22.9 0.1 9.3e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMC96751.1 - 0.00042 19.5 0.1 0.00052 19.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EMC96751.1 - 0.00061 20.0 0.1 0.086 13.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC96751.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EMC96751.1 - 0.0016 17.6 0.1 0.012 14.9 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EMC96751.1 - 0.0027 16.9 0.1 0.014 14.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMC96751.1 - 0.016 15.1 0.1 0.083 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EMC96751.1 - 0.021 14.7 0.2 0.063 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC96751.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EMC96751.1 - 0.042 13.5 0.1 0.094 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.13 EMC96751.1 - 0.05 12.6 0.1 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 EMC96751.1 - 0.062 13.5 0.1 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EMC96751.1 - 0.071 12.5 0.1 0.5 9.8 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Aminotran_5 PF00266.14 EMC96753.1 - 1e-17 63.9 0.0 2.5e-11 42.9 0.0 2.3 2 1 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.15 EMC96754.1 - 9.1e-65 218.9 0.0 7.1e-40 136.8 0.0 2.5 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMC96754.1 - 1.5e-23 83.3 0.0 2.8e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain GYF PF02213.11 EMC96756.1 - 7.8e-17 60.6 0.3 1.6e-16 59.5 0.2 1.6 1 0 0 1 1 1 1 GYF domain GST_N_3 PF13417.1 EMC96757.1 - 1e-13 51.3 0.0 2.6e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC96757.1 - 1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC96757.1 - 7.2e-09 35.5 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC96757.1 - 2.6e-08 33.7 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC96757.1 - 0.00092 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC96757.1 - 0.0017 18.8 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EMC96757.1 - 0.17 12.2 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 MetRS-N binding domain NUDIX PF00293.23 EMC96758.1 - 8.2e-17 61.1 0.0 1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EMC96758.1 - 0.023 14.1 0.0 0.027 13.8 0.0 1.3 1 1 0 1 1 1 0 NUDIX domain Septin PF00735.13 EMC96760.1 - 5e-123 409.5 0.1 5e-123 409.5 0.1 1.9 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMC96760.1 - 1.4e-07 31.4 0.0 2.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC96760.1 - 7.4e-06 25.5 0.8 0.00033 20.1 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMC96760.1 - 6.2e-05 22.2 0.2 0.00039 19.6 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMC96760.1 - 0.00028 21.1 2.2 0.021 15.1 0.0 2.7 3 0 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 EMC96760.1 - 0.00047 19.6 0.6 0.0014 18.1 0.1 2.0 2 1 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 EMC96760.1 - 0.0012 17.9 1.7 0.0022 17.1 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 EMC96760.1 - 0.0015 18.5 0.0 0.014 15.4 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 EMC96760.1 - 0.0023 18.4 0.4 0.0082 16.6 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 EMC96760.1 - 0.0033 17.5 0.1 0.016 15.3 0.0 2.3 2 2 1 3 3 2 1 AAA domain Ras PF00071.17 EMC96760.1 - 0.0035 16.7 0.0 0.0095 15.3 0.0 1.7 1 0 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.13 EMC96760.1 - 0.0051 16.2 0.0 0.016 14.6 0.0 1.9 2 0 0 2 2 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EMC96760.1 - 0.0054 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EMC96760.1 - 0.01 15.3 0.7 1.4 8.3 0.0 3.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EMC96760.1 - 0.021 14.6 7.1 0.57 9.9 0.0 3.4 3 1 0 3 3 3 0 Dynamin family AAA_25 PF13481.1 EMC96760.1 - 0.036 13.4 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMC96760.1 - 0.062 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EMC96760.1 - 0.068 12.7 0.5 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EMC96760.1 - 0.073 12.7 0.1 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EMC96760.1 - 0.074 13.2 0.9 0.34 11.1 0.0 2.5 3 0 0 3 3 2 0 RNA helicase Exonuc_VII_L PF02601.10 EMC96760.1 - 0.29 10.2 5.2 0.55 9.3 3.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.6 EMC96760.1 - 0.41 9.8 6.4 0.63 9.2 4.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 EMC96760.1 - 9.7 5.7 11.2 15 5.0 7.8 1.3 1 0 0 1 1 1 0 IncA protein Exo70 PF03081.10 EMC96761.1 - 4.2e-78 262.7 0.0 2.3e-77 260.3 0.0 2.0 2 1 0 2 2 2 1 Exo70 exocyst complex subunit GAS PF13851.1 EMC96761.1 - 0.00064 18.9 5.0 0.31 10.2 0.1 2.6 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF883 PF05957.8 EMC96761.1 - 0.037 14.4 0.2 23 5.4 0.0 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) COG5 PF10392.4 EMC96761.1 - 0.11 12.4 2.9 0.38 10.7 0.1 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DASH_Duo1 PF08651.5 EMC96761.1 - 0.82 9.2 9.1 7.9 6.1 0.0 4.8 5 1 1 6 6 6 0 DASH complex subunit Duo1 NPV_P10 PF05531.7 EMC96761.1 - 1.6 9.0 5.2 1.4 9.2 0.1 3.6 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 EMC96762.1 - 2.8e-39 134.8 29.5 2.8e-39 134.8 20.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC96762.1 - 0.00022 19.5 3.0 0.00022 19.5 2.1 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) TMEM169 PF15052.1 EMC96762.1 - 0.019 14.8 0.4 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 TMEM169 protein family HSP70 PF00012.15 EMC96764.1 - 3.1e-162 540.6 1.4 3.1e-162 540.6 1.0 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EMC96764.1 - 6.8e-13 47.9 0.0 4.1e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EMC96764.1 - 0.00038 20.2 1.2 0.036 13.8 0.1 3.3 3 1 0 3 3 3 1 Cell division protein FtsA p450 PF00067.17 EMC96765.1 - 3.1e-58 197.4 0.0 4.2e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tir_receptor_M PF03549.9 EMC96767.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain ABC_membrane_2 PF06472.10 EMC96768.1 - 2e-109 365.1 2.4 2e-109 365.1 1.7 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMC96768.1 - 4.8e-16 59.3 0.0 1.3e-15 57.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC96768.1 - 0.00021 21.3 1.8 0.0006 19.8 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.1 EMC96768.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC96768.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMC96768.1 - 0.032 14.2 0.5 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 EMC96768.1 - 0.042 13.0 0.3 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.7 EMC96768.1 - 0.042 12.8 0.4 0.75 8.7 0.0 3.0 4 0 0 4 4 4 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC96768.1 - 0.1 12.7 0.1 1.8 8.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain DUF258 PF03193.11 EMC96768.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GrpE PF01025.14 EMC96769.1 - 2.7e-45 153.9 0.6 3.6e-45 153.5 0.4 1.1 1 0 0 1 1 1 1 GrpE Solute_trans_a PF03619.11 EMC96770.1 - 1.9e-99 332.4 0.7 2.3e-99 332.1 0.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PsbY PF06298.6 EMC96770.1 - 0.094 12.2 1.7 0.22 11.1 1.2 1.6 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) DivIC PF04977.10 EMC96772.1 - 0.0063 15.9 0.0 0.0063 15.9 0.0 2.1 2 1 0 2 2 2 1 Septum formation initiator DUF2046 PF09755.4 EMC96772.1 - 0.19 10.6 5.1 0.049 12.5 0.5 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) DUF2968 PF11180.3 EMC96772.1 - 0.77 9.1 12.8 0.65 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) PLDc_2 PF13091.1 EMC96773.1 - 8.2e-19 67.5 0.0 5.6e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMC96773.1 - 0.0004 20.1 0.1 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EMC96773.1 - 0.00067 18.6 0.0 0.0034 16.3 0.0 2.1 2 1 0 2 2 2 1 Archaeal transcriptional regulator TrmB ADH_zinc_N PF00107.21 EMC96774.1 - 3e-19 68.8 1.2 3e-19 68.8 0.8 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_26 PF13659.1 EMC96774.1 - 0.0066 16.4 0.4 0.69 9.9 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain TrkA_N PF02254.13 EMC96774.1 - 0.02 14.9 0.5 0.09 12.7 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain DapB_N PF01113.15 EMC96774.1 - 0.057 13.3 0.9 0.099 12.5 0.6 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_18 PF12847.2 EMC96774.1 - 0.061 13.9 0.3 16 6.0 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase domain MTS PF05175.9 EMC96774.1 - 0.087 12.1 0.1 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Cytochrom_C PF00034.16 EMC96776.1 - 4e-08 33.9 0.0 6.1e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EMC96776.1 - 1.6e-07 31.3 0.5 1.2e-06 28.5 0.4 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EMC96776.1 - 0.00064 19.1 0.1 0.0066 15.8 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 EMC96776.1 - 0.067 12.8 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Stc1 PF12898.2 EMC96777.1 - 3.9e-15 55.6 8.0 5.7e-15 55.1 5.6 1.2 1 0 0 1 1 1 1 Stc1 domain TNFR_c6 PF00020.13 EMC96777.1 - 0.04 13.9 4.2 0.04 13.9 2.9 2.1 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region zf-HYPF PF07503.7 EMC96777.1 - 0.081 12.3 0.3 0.081 12.3 0.2 2.5 3 0 0 3 3 3 0 HypF finger Dehyd-heme_bind PF09098.5 EMC96777.1 - 0.15 11.4 2.6 0.12 11.8 0.7 1.6 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding CGGC PF08821.6 EMC96777.1 - 0.49 10.4 4.3 1.6 8.8 2.9 1.9 1 1 1 2 2 2 0 CGGC domain DUF4559 PF15112.1 EMC96777.1 - 1.4 8.0 6.1 1.8 7.6 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Cytochrom_c3_2 PF14537.1 EMC96777.1 - 3.6 7.9 7.7 16 5.9 5.3 1.9 1 1 0 1 1 1 0 Cytochrome c3 zf-DNL PF05180.7 EMC96777.1 - 7.2 6.4 7.8 2.3 8.0 0.0 2.9 3 0 0 3 3 3 0 DNL zinc finger Chorismate_bind PF00425.13 EMC96779.1 - 1.6e-86 289.8 0.2 2e-72 243.6 0.0 2.8 2 1 0 3 3 3 2 chorismate binding enzyme Anth_synt_I_N PF04715.8 EMC96779.1 - 7.7e-29 100.5 0.2 4.4e-25 88.3 0.0 3.1 2 1 1 3 3 3 2 Anthranilate synthase component I, N terminal region AA_permease_N PF08403.5 EMC96779.1 - 0.042 13.1 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Amino acid permease N-terminal APG6 PF04111.7 EMC96780.1 - 0.55 9.2 4.2 1.2 8.0 2.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Myb_DNA-bind_5 PF13873.1 EMC96780.1 - 0.99 9.3 3.8 33 4.4 0.4 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ATP-synt_ab PF00006.20 EMC96781.1 - 2.2e-61 207.1 0.0 3.1e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMC96781.1 - 7.3e-16 58.6 0.1 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMC96781.1 - 7.2e-13 48.5 0.7 1.5e-12 47.5 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMC96781.1 - 0.00015 21.6 0.3 0.00036 20.3 0.2 1.6 1 0 0 1 1 1 1 HAS barrel domain LIM_bind PF01803.11 EMC96782.1 - 9.6e-41 139.4 0.5 9.6e-41 139.4 0.3 5.8 3 2 4 7 7 7 1 LIM-domain binding protein Pex16 PF08610.5 EMC96784.1 - 2.4e-102 342.3 0.1 2.7e-102 342.2 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) PLDc_2 PF13091.1 EMC96787.1 - 1.2e-14 54.1 0.0 3.1e-05 23.6 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 EMC96787.1 - 1.3e-14 53.3 3.6 1e-07 31.5 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DAO PF01266.19 EMC96788.1 - 7.1e-52 176.4 0.1 9.1e-52 176.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC96788.1 - 5.4e-07 29.5 0.4 1.3e-06 28.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMC96788.1 - 0.00015 21.8 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMC96788.1 - 0.0011 18.4 0.2 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EMC96788.1 - 0.0032 17.4 0.1 0.0055 16.6 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EMC96788.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EMC96788.1 - 0.022 13.6 0.5 0.039 12.8 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMC96788.1 - 0.03 14.0 0.2 0.05 13.3 0.2 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EMC96788.1 - 0.031 12.7 0.5 0.043 12.2 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EMC96788.1 - 0.033 14.0 0.1 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC96788.1 - 0.037 13.0 0.2 0.06 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EMC96788.1 - 0.092 11.5 0.9 0.19 10.5 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EMC96788.1 - 0.15 11.1 0.1 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Glyco_hydro_30 PF02055.11 EMC96790.1 - 8.5e-32 109.9 0.2 1.3e-31 109.3 0.2 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Choline_transpo PF04515.7 EMC96791.1 - 4.9e-13 48.5 14.8 4.9e-13 48.5 10.3 3.0 3 0 0 3 3 3 2 Plasma-membrane choline transporter CLPTM1 PF05602.7 EMC96792.1 - 8.9e-149 495.9 0.0 1.1e-148 495.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1240 PF06836.7 EMC96792.1 - 0.79 9.9 5.1 2.3 8.4 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) 2TM PF13239.1 EMC96792.1 - 0.94 9.5 7.7 0.095 12.7 0.7 2.8 2 1 1 3 3 3 0 2TM domain Sec16_C PF12931.2 EMC96793.1 - 1.2e-84 284.4 0.0 1.6e-84 284.0 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EMC96793.1 - 3.4e-26 91.5 0.0 7.6e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Borrelia_P83 PF05262.6 EMC96793.1 - 3.3 5.8 5.7 6.1 4.9 3.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein EHN PF06441.7 EMC96794.1 - 1.7e-33 114.8 0.3 3e-33 114.0 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 EMC96794.1 - 2.8e-06 27.0 0.2 1.2e-05 25.0 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC96794.1 - 3.2e-05 23.9 0.7 8.7e-05 22.5 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Rad51 PF08423.6 EMC96795.1 - 0.066 12.1 0.0 0.09 11.6 0.0 1.1 1 0 0 1 1 1 0 Rad51 Carn_acyltransf PF00755.15 EMC96797.1 - 2.1e-163 544.6 0.0 3.3e-150 501.0 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Med26 PF08711.6 EMC96798.1 - 1.1e-12 47.2 0.0 1.8e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.1 EMC96799.1 - 1.6e-33 115.3 3.6 3.4e-33 114.2 2.5 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EMC96799.1 - 3.1e-11 43.4 34.1 3.1e-11 43.4 23.6 2.1 1 1 0 1 1 1 1 Nucleoporin FG repeat region SlyX PF04102.7 EMC96799.1 - 0.085 13.2 1.8 10 6.5 0.2 3.4 2 1 1 3 3 3 0 SlyX FUSC PF04632.7 EMC96799.1 - 0.66 8.3 8.2 1.2 7.5 5.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family E1-N PF14463.1 EMC96800.1 - 0.12 11.9 1.9 3.1 7.3 0.1 2.9 2 1 1 3 3 3 0 E1 N-terminal domain Tom5 PF10642.4 EMC96801.1 - 8e-17 60.6 0.2 8.3e-17 60.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase CHCH PF06747.8 EMC96802.1 - 3.4e-09 36.3 12.6 6.5e-08 32.3 4.1 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 EMC96802.1 - 0.0038 16.9 13.7 0.011 15.4 3.3 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EMC96802.1 - 0.16 12.0 12.5 1.6 8.7 4.7 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EMC96802.1 - 0.47 10.5 11.9 0.68 9.9 3.0 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb PCMT PF01135.14 EMC96803.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EMC96803.1 - 0.0073 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC96803.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMC96803.1 - 0.025 15.1 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EMC96803.1 - 0.056 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase LSM PF01423.17 EMC96805.1 - 5.6e-17 61.0 0.0 8.4e-17 60.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMC96805.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain RAM PF15320.1 EMC96805.1 - 3.6 7.9 8.4 5.1 7.4 5.8 1.3 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein gp37_C PF12604.3 EMC96807.1 - 0.14 11.9 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Tail fiber protein gp37 C terminal Cyclin_N PF00134.18 EMC96808.1 - 2.5e-09 36.7 0.1 9.7e-08 31.6 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF2183 PF09949.4 EMC96809.1 - 0.16 11.9 0.7 0.59 10.0 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) V-SNARE_C PF12352.3 EMC96809.1 - 0.83 9.7 12.0 1.5 8.9 1.6 4.0 4 1 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus DUF630 PF04783.7 EMC96809.1 - 0.94 9.4 6.3 8 6.4 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF630) Reo_sigmaC PF04582.7 EMC96809.1 - 3.9 6.5 5.7 9.2 5.3 0.1 2.9 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Bul1_C PF04426.7 EMC96809.1 - 4.6 6.3 13.8 0.29 10.3 4.2 2.5 3 0 0 3 3 3 0 Bul1 C terminus DUF3573 PF12097.3 EMC96809.1 - 8.8 4.8 7.9 0.23 10.0 0.9 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3573) RRM_5 PF13893.1 EMC96811.1 - 3.2e-07 30.1 0.1 6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC96811.1 - 8.8e-07 28.8 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EMC96811.1 - 4.9e-06 26.5 0.0 9.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EMC96811.1 - 6.3e-06 25.7 0.1 1.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EMC96811.1 - 0.022 14.4 3.2 0.044 13.4 2.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 EMC96811.1 - 0.031 14.1 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) PDCD9 PF07147.7 EMC96811.1 - 0.096 11.4 0.2 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) RRM_3 PF08777.6 EMC96811.1 - 0.098 12.5 2.4 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif APG6 PF04111.7 EMC96811.1 - 2.7 6.9 5.6 4.1 6.3 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GTP_EFTU PF00009.22 EMC96813.1 - 6.1e-62 208.3 0.1 8.9e-62 207.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMC96813.1 - 1.6e-38 130.9 0.0 4.7e-38 129.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMC96813.1 - 6.4e-23 80.4 0.0 1.9e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMC96813.1 - 1.4e-14 53.8 1.3 9.3e-14 51.3 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMC96813.1 - 1.4e-11 44.0 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EMC96813.1 - 2.4e-05 24.2 0.2 5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.27 EMC96814.1 - 2.8e-11 42.8 8.5 0.019 14.8 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Myb_DNA-bind_6 PF13921.1 EMC96814.1 - 0.034 14.2 0.1 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain AhpC-TSA PF00578.16 EMC96815.1 - 2.8e-07 30.2 0.0 5.3e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMC96815.1 - 1.7e-06 27.6 0.0 0.00027 20.5 0.0 2.1 2 0 0 2 2 2 2 Redoxin AhpC-TSA_2 PF13911.1 EMC96815.1 - 8.4e-05 22.4 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.1 EMC96815.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like UPF0121 PF03661.8 EMC96817.1 - 5.5e-12 45.4 3.2 8.8e-12 44.7 2.3 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) FA_desaturase PF00487.19 EMC96817.1 - 8.9 5.6 11.4 0.29 10.5 2.2 2.1 1 1 1 2 2 2 0 Fatty acid desaturase Pribosyltran_N PF13793.1 EMC96819.1 - 5.8e-41 138.8 0.1 2.1e-40 137.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EMC96819.1 - 5.8e-35 120.7 0.0 1.5e-28 99.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EMC96819.1 - 7.9e-05 22.3 0.0 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Aldo_ket_red PF00248.16 EMC96820.1 - 7.8e-65 218.4 0.1 8.9e-65 218.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ubiquitin PF00240.18 EMC96821.1 - 3.6e-34 115.9 0.9 4.9e-34 115.5 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMC96821.1 - 1.4e-19 69.5 0.7 1.9e-19 69.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC96821.1 - 1.7e-05 24.9 0.2 5.8e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMC96821.1 - 0.0025 17.5 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMC96821.1 - 0.012 15.5 0.1 0.037 13.9 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EMC96821.1 - 0.02 14.9 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF2407 PF10302.4 EMC96821.1 - 0.021 14.9 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain eIF-5a PF01287.15 EMC96824.1 - 1.4e-27 95.3 1.3 2.1e-27 94.8 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EMC96824.1 - 0.001 18.6 0.4 0.0025 17.4 0.3 1.7 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EMC96824.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 EMC96825.1 - 2.3e-117 392.6 0.0 2.9e-117 392.2 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EMC96825.1 - 1.8e-05 23.0 0.2 2.7e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF1664 PF07889.7 EMC96825.1 - 0.03 14.1 0.3 0.076 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Mer2 PF09074.5 EMC96825.1 - 0.036 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Mer2 DnaI_N PF07319.6 EMC96825.1 - 0.21 11.8 1.7 1.8 8.8 0.0 3.0 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus Seryl_tRNA_N PF02403.17 EMC96825.1 - 0.33 10.9 4.5 0.6 10.1 0.4 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 EMC96825.1 - 0.38 11.0 2.1 2.7 8.3 0.3 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EMC96825.1 - 0.38 10.3 5.1 0.1 12.2 1.1 1.7 2 0 0 2 2 2 0 IncA protein SSP160 PF06933.6 EMC96826.1 - 1.8 6.4 14.1 2.4 6.0 9.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 adh_short PF00106.20 EMC96827.1 - 7.4e-14 52.0 0.0 1.2e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC96827.1 - 9.6e-07 28.6 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3439 PF11921.3 EMC96828.1 - 0.0028 17.3 9.7 0.0065 16.2 6.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EMC96828.1 - 0.015 13.0 1.9 0.019 12.7 1.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 EMC96828.1 - 0.3 9.0 10.9 0.44 8.4 7.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 S4 PF01479.20 EMC96829.1 - 4.2e-15 54.9 0.0 7.6e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EMC96829.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 S4 domain Seryl_tRNA_N PF02403.17 EMC96829.1 - 2.7 8.0 9.8 1.8 8.6 2.5 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BTV_NS2 PF04514.7 EMC96829.1 - 9.8 4.9 11.4 14 4.4 7.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 La PF05383.12 EMC96830.1 - 8.3e-14 51.1 0.0 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EMC96830.1 - 4.8e-09 36.0 0.0 1.3e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC96830.1 - 1.6e-07 30.8 0.0 4.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC96830.1 - 0.0078 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.26 EMC96831.1 - 5.3e-09 36.0 0.0 8.1e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C4_ClpX PF06689.8 EMC96831.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger AAA PF00004.24 EMC96832.1 - 6e-11 42.6 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC96832.1 - 8.7e-06 25.5 0.0 2.5e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EMC96832.1 - 1.3e-05 24.0 0.0 2.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EMC96832.1 - 2.8e-05 23.3 0.0 5.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC96832.1 - 9.9e-05 22.4 0.0 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC96832.1 - 0.00011 21.9 0.0 0.00057 19.5 0.0 2.3 2 0 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 EMC96832.1 - 0.0011 18.8 0.0 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMC96832.1 - 0.0026 18.5 0.0 0.011 16.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC96832.1 - 0.0072 16.3 0.1 0.054 13.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMC96832.1 - 0.008 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMC96832.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMC96832.1 - 0.019 14.0 0.6 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 EMC96832.1 - 0.023 14.3 0.3 0.11 12.1 0.0 2.2 1 1 0 1 1 1 0 NTPase AAA_18 PF13238.1 EMC96832.1 - 0.046 14.0 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0180 PF03698.8 EMC96832.1 - 0.063 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) IstB_IS21 PF01695.12 EMC96832.1 - 0.088 12.2 0.1 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.17 EMC96832.1 - 0.15 10.9 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EMC96833.1 - 2.7e-15 56.7 0.0 1.3e-14 54.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMC96833.1 - 9.1e-05 22.1 0.1 0.00021 20.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EMC96833.1 - 0.00097 18.8 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMC96833.1 - 0.0031 18.3 0.0 0.025 15.4 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC96833.1 - 0.0056 16.8 0.5 0.074 13.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC96833.1 - 0.075 13.0 1.9 0.46 10.4 0.7 2.4 1 1 1 2 2 2 0 AAA ATPase domain PPR_2 PF13041.1 EMC96834.1 - 2.5e-11 43.3 0.0 1.2 9.1 0.0 7.9 7 2 1 8 8 8 4 PPR repeat family PPR_3 PF13812.1 EMC96834.1 - 4.6e-09 35.8 5.6 0.55 10.6 0.0 7.9 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR PF01535.15 EMC96834.1 - 1.2e-06 28.0 0.4 15 5.8 0.0 7.1 8 1 0 8 8 8 2 PPR repeat TPR_19 PF14559.1 EMC96834.1 - 0.0025 18.1 0.1 0.86 9.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_1 PF12854.2 EMC96834.1 - 0.011 15.2 1.5 0.5 9.8 0.0 4.3 4 0 0 4 4 4 0 PPR repeat EBV-NA1 PF02905.9 EMC96835.1 - 0.18 11.2 0.7 0.36 10.2 0.5 1.4 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain AF-4 PF05110.8 EMC96836.1 - 0.0049 14.8 5.2 0.0056 14.6 3.6 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.7 EMC96836.1 - 0.14 11.8 9.3 0.19 11.4 6.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2201_N PF13203.1 EMC96836.1 - 0.16 11.1 9.3 0.19 10.9 6.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.2 EMC96836.1 - 1.6 6.2 4.2 1.7 6.1 2.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U79_P34 PF03064.11 EMC96836.1 - 3.6 7.0 10.0 2.1 7.7 5.8 1.5 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Zip PF02535.17 EMC96837.1 - 3.5e-50 170.8 0.3 4.4e-50 170.4 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 EMC96837.1 - 0.091 11.9 2.8 0.089 11.9 0.4 1.9 2 0 0 2 2 2 0 UNC-50 family Pirin PF02678.11 EMC96838.1 - 1.9e-26 92.0 0.3 3.7e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EMC96838.1 - 0.0016 17.8 1.2 0.018 14.5 0.1 2.8 3 1 0 3 3 3 1 Cupin domain adh_short PF00106.20 EMC96839.1 - 4.1e-16 59.3 0.3 8.6e-16 58.2 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC96839.1 - 2.1e-08 34.0 0.2 3e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.1 EMC96841.1 - 0.0031 17.6 0.0 0.0066 16.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_4 PF07993.7 EMC96842.1 - 1.4e-35 122.4 0.0 1.2e-34 119.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EMC96842.1 - 2.2e-35 121.9 0.0 4.6e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMC96842.1 - 8.7e-14 51.5 0.0 2.4e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMC96842.1 - 1.3e-05 25.3 0.1 0.00027 21.1 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EMC96842.1 - 0.00051 18.8 0.0 0.0038 15.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMC96842.1 - 0.002 18.0 0.6 0.0062 16.4 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC96842.1 - 0.015 14.9 0.2 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 KR domain NmrA PF05368.8 EMC96842.1 - 0.016 14.4 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family FAM216B PF15107.1 EMC96842.1 - 0.021 14.6 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 FAM216B protein family NAD_binding_10 PF13460.1 EMC96842.1 - 0.022 14.7 0.1 0.36 10.8 0.1 2.4 2 0 0 2 2 2 0 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC96842.1 - 0.024 13.5 0.0 4.6 6.0 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EMC96842.1 - 0.028 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EMC96843.1 - 2.5e-15 56.7 0.3 4.7e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC96843.1 - 2.4e-09 37.0 0.1 4.1e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 EMC96844.1 - 1.7e-11 43.5 0.0 2.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC96844.1 - 1.3e-06 28.2 9.2 1.3e-06 28.2 6.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Telomere_Sde2 PF13019.1 EMC96845.1 - 1.5e-63 213.2 0.1 1.5e-63 213.2 0.1 1.4 2 0 0 2 2 2 1 Telomere stability and silencing TP53IP5 PF15331.1 EMC96845.1 - 0.63 9.9 6.0 0.7 9.7 3.4 1.5 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 p450 PF00067.17 EMC96846.1 - 5.3e-41 140.6 0.0 6.8e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_63 PF03200.11 EMC96847.1 - 5.8e-07 27.7 13.9 2.2e-05 22.5 3.3 4.5 4 1 0 4 4 4 3 Mannosyl oligosaccharide glucosidase HSP70 PF00012.15 EMC96848.1 - 3.2e-15 55.0 0.0 9.7e-14 50.1 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Rad21_Rec8_N PF04825.8 EMC96849.1 - 0.054 13.4 0.2 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein AAA_23 PF13476.1 EMC96849.1 - 0.12 12.6 0.8 0.23 11.7 0.5 1.4 1 0 0 1 1 1 0 AAA domain DUF4510 PF14971.1 EMC96849.1 - 0.51 10.4 5.2 0.27 11.3 1.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) Rootletin PF15035.1 EMC96849.1 - 0.81 9.6 13.7 0.82 9.6 8.4 1.8 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Kinesin-relat_1 PF12711.2 EMC96849.1 - 0.95 9.9 12.1 1.4 9.3 6.7 2.5 2 0 0 2 2 2 0 Kinesin motor Lzipper-MIP1 PF14389.1 EMC96849.1 - 1.6 8.8 13.7 0.22 11.6 2.9 3.2 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 MMR_HSR1 PF01926.18 EMC96850.1 - 1.7e-07 31.1 0.0 5.6e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC96850.1 - 0.017 14.3 0.1 7.6 5.7 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B GFA PF04828.9 EMC96850.1 - 0.11 12.3 0.1 8.7 6.3 0.0 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Glyco_transf_34 PF05637.7 EMC96851.1 - 2.4e-63 213.8 0.0 4.3e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family LRR_8 PF13855.1 EMC96851.1 - 3.4e-13 49.1 1.4 0.00097 18.8 0.0 4.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EMC96851.1 - 2e-07 30.3 0.3 0.21 11.7 0.0 6.3 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.2 EMC96851.1 - 6.4e-07 28.8 2.4 0.046 13.3 0.0 5.6 3 2 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC96851.1 - 0.0042 16.9 1.4 88 3.7 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 EMC96851.1 - 0.018 15.1 7.6 58 4.5 0.0 6.9 7 1 2 9 9 9 0 Leucine rich repeat TATR PF03430.8 EMC96851.1 - 1 7.8 4.3 1.5 7.3 3.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF4407 PF14362.1 EMC96851.1 - 2.2 7.1 9.1 3.5 6.4 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ACT_3 PF10000.4 EMC96852.1 - 5.1e-18 64.5 0.0 1e-17 63.6 0.0 1.5 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.1 EMC96852.1 - 4.7e-08 32.4 0.0 7.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 ACT domain ADH_N PF08240.7 EMC96853.1 - 3e-27 94.5 0.9 5.5e-27 93.6 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC96853.1 - 2e-23 82.3 1.7 2.8e-23 81.9 1.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC96853.1 - 0.00018 22.3 0.7 0.00039 21.3 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_32 PF13679.1 EMC96853.1 - 0.12 12.0 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.7 EMC96854.1 - 3.9e-25 87.7 4.4 7.2e-25 86.8 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC96854.1 - 4.3e-14 52.1 0.0 6e-13 48.4 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMC96854.1 - 0.00047 19.7 0.0 0.00087 18.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EMC96854.1 - 0.0012 18.0 0.1 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMC96854.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 EMC96854.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.7 EMC96855.1 - 1.2e-29 102.2 2.9 3.4e-28 97.5 2.2 2.8 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC96855.1 - 1.2e-26 92.7 0.2 2.6e-26 91.7 0.1 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EMC96855.1 - 1.6e-06 27.6 0.0 4.2e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 EMC96855.1 - 0.00041 20.3 0.1 0.00071 19.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.22 EMC96855.1 - 0.002 18.5 0.0 0.0063 16.9 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMC96855.1 - 0.0022 18.2 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding CPSase_L_chain PF00289.17 EMC96855.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Pyr_redox_2 PF07992.9 EMC96855.1 - 0.027 14.3 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMC96855.1 - 0.035 14.2 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EMC96855.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NTP_transf_3 PF12804.2 EMC96855.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 MobA-like NTP transferase domain Chitin_synth_2 PF03142.10 EMC96857.1 - 2.4e-233 775.3 0.0 3.1e-233 774.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EMC96857.1 - 1.1e-55 189.0 0.0 8.6e-50 169.5 0.0 2.6 2 1 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.23 EMC96857.1 - 3.7e-17 61.8 0.9 6.7e-12 45.0 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EMC96857.1 - 1e-15 57.9 2.0 1e-15 57.9 1.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC96857.1 - 2.3e-15 56.9 0.0 3.8e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.6 EMC96857.1 - 4.3e-13 48.8 0.7 4.4e-12 45.5 0.8 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EMC96857.1 - 3e-06 26.6 0.0 6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMC96857.1 - 0.038 13.6 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 PAT1 PF09770.4 EMC96857.1 - 6.8 4.8 17.5 10 4.2 12.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chitin_synth_2 PF03142.10 EMC96859.1 - 1.3e-251 835.5 0.2 1.8e-251 835.1 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EMC96859.1 - 2.4e-166 554.7 0.0 3.3e-166 554.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EMC96859.1 - 4.3e-18 64.8 0.0 3.9e-13 48.9 0.0 2.9 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EMC96859.1 - 1.9e-16 59.5 0.2 8e-16 57.5 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EMC96859.1 - 9.3e-16 58.1 3.0 2.7e-15 56.5 2.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMC96859.1 - 6.8e-13 48.9 0.1 1.1e-10 41.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC96859.1 - 0.00034 20.3 0.0 0.023 14.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_22 PF13401.1 EMC96859.1 - 0.02 15.0 0.1 0.081 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EMC96859.1 - 0.021 14.7 0.0 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EMC96859.1 - 0.026 14.5 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Glyco_transf_21 PF13506.1 EMC96859.1 - 0.027 13.7 0.2 0.096 11.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF258 PF03193.11 EMC96859.1 - 0.034 13.3 0.0 0.088 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMC96859.1 - 0.038 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EMC96859.1 - 0.045 13.2 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EMC96859.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EMC96859.1 - 0.35 9.6 0.0 0.61 8.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 EMC96859.1 - 0.46 10.7 0.0 1.1 9.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 EMC96861.1 - 5.4e-22 78.4 0.5 4.4e-21 75.5 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC96861.1 - 1.7e-13 50.9 0.4 2e-12 47.3 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC96861.1 - 1.5e-07 31.2 2.7 3.6e-07 30.0 0.2 2.2 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMC96861.1 - 0.017 15.1 0.3 0.44 10.5 0.2 2.4 2 1 0 2 2 2 0 NADH(P)-binding NmrA PF05368.8 EMC96861.1 - 0.018 14.3 0.2 0.033 13.4 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family Amidase PF01425.16 EMC96862.1 - 1.5e-95 320.6 0.0 1.8e-95 320.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Palm_thioest PF02089.10 EMC96863.1 - 1.5e-47 161.9 0.0 2e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase CD20 PF04103.10 EMC96864.1 - 0.13 12.1 1.3 0.39 10.6 0.9 1.8 1 1 0 1 1 1 0 CD20-like family DUF4210 PF13915.1 EMC96865.1 - 9.6e-26 89.8 0.0 1.9e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EMC96865.1 - 1.8e-21 75.7 0.4 4.2e-21 74.5 0.3 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis Cgr1 PF03879.9 EMC96866.1 - 0.0026 17.8 8.3 0.0026 17.8 5.7 2.4 2 0 0 2 2 2 1 Cgr1 family vMSA PF00695.14 EMC96866.1 - 0.59 9.2 4.4 0.72 8.9 3.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Hex_IIIa PF02455.11 EMC96866.1 - 3.1 6.3 7.7 3.7 6.1 5.4 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) RFXA_RFXANK_bdg PF15289.1 EMC96866.1 - 4.5 7.4 9.1 0.57 10.3 1.9 2.2 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Sec62 PF03839.11 EMC96867.1 - 2.2e-57 194.0 3.3 2.2e-57 194.0 2.3 2.1 2 0 0 2 2 2 1 Translocation protein Sec62 DUF2201_N PF13203.1 EMC96867.1 - 0.045 12.9 10.8 0.21 10.7 0.3 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF3408 PF11888.3 EMC96867.1 - 0.46 10.4 0.1 0.46 10.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3408) Ribosomal_L11_N PF03946.9 EMC96868.1 - 9.7e-18 63.3 0.0 1.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EMC96868.1 - 1.7e-10 40.8 0.7 2.8e-10 40.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HET PF06985.6 EMC96869.1 - 5e-18 65.5 0.0 6.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EMC96870.1 - 1.6e-26 92.8 39.8 2e-26 92.5 27.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EMC96870.1 - 0.72 9.9 10.0 0.098 12.6 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Sugar_tr PF00083.19 EMC96871.1 - 6.2e-82 275.5 25.3 7.5e-82 275.2 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96871.1 - 3.6e-24 85.1 35.8 7.7e-24 84.0 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMC96871.1 - 3.6e-05 22.1 2.4 3.6e-05 22.1 1.7 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Rick_17kDa_Anti PF05433.10 EMC96871.1 - 0.37 10.4 4.9 0.15 11.7 1.0 2.3 2 1 0 2 2 2 0 Glycine zipper 2TM domain Glyco_hydro_43 PF04616.9 EMC96872.1 - 4.7e-78 262.1 0.4 7.5e-78 261.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Zn_clus PF00172.13 EMC96873.1 - 5.8e-10 38.9 7.5 1.1e-09 38.0 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC96873.1 - 5.6e-08 31.9 0.0 8.3e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MiaE_2 PF13794.1 EMC96875.1 - 0.081 12.4 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Pho88 PF10032.4 EMC96876.1 - 3.5e-39 134.0 0.3 3.4e-38 130.7 0.2 1.9 1 1 0 1 1 1 1 Phosphate transport (Pho88) ThiF PF00899.16 EMC96878.1 - 2.4e-16 59.8 0.0 3.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF2305 PF10230.4 EMC96879.1 - 7e-47 160.0 0.0 8.8e-40 136.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EMC96879.1 - 5.3e-06 26.4 1.4 0.00013 21.9 1.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC96879.1 - 0.00017 21.3 0.0 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ribosomal_S3Ae PF01015.13 EMC96880.1 - 1.1e-79 266.2 4.5 1.3e-79 266.0 3.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EMC96880.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ham1p_like PF01725.11 EMC96881.1 - 1.8e-53 180.7 0.0 2e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EMC96882.1 - 1.4e-26 93.2 0.1 1.4e-26 93.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMC96882.1 - 2.2e-15 57.5 2.1 6.8e-15 55.9 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EMC96882.1 - 3.9e-05 23.6 0.0 7.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC96882.1 - 3.9e-05 23.5 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMC96882.1 - 0.00069 19.7 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMC96882.1 - 0.00098 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EMC96882.1 - 0.001 18.9 0.2 0.01 15.7 0.1 2.2 1 1 0 1 1 1 1 Shikimate kinase KTI12 PF08433.5 EMC96882.1 - 0.0043 16.2 0.0 0.0086 15.3 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_25 PF13481.1 EMC96882.1 - 0.0046 16.3 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC96882.1 - 0.0047 16.6 0.1 0.0098 15.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMC96882.1 - 0.0096 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 EMC96882.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EMC96882.1 - 0.014 15.1 1.3 0.014 15.1 0.9 1.8 2 1 0 2 2 2 0 NTPase ADK PF00406.17 EMC96882.1 - 0.017 15.0 1.1 0.33 10.8 0.0 2.2 1 1 0 2 2 2 0 Adenylate kinase AAA_10 PF12846.2 EMC96882.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EMC96882.1 - 0.019 14.4 0.2 0.058 12.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EMC96882.1 - 0.019 14.8 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMC96882.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EMC96882.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EMC96882.1 - 0.024 13.9 0.2 0.34 10.1 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 EMC96882.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin2 PF13189.1 EMC96882.1 - 0.027 14.3 0.1 0.051 13.4 0.1 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_5 PF07728.9 EMC96882.1 - 0.028 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 EMC96882.1 - 0.042 13.5 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EMC96882.1 - 0.06 13.5 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.12 EMC96882.1 - 0.067 12.5 0.1 5.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.16 EMC96882.1 - 0.087 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EMC96882.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.17 EMC96882.1 - 0.11 11.8 0.1 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EMC96882.1 - 0.12 11.2 0.1 0.29 10.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Abhydrolase_6 PF12697.2 EMC96883.1 - 2.3e-30 106.1 0.0 1.4e-29 103.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC96883.1 - 1.1e-21 77.4 0.0 1.6e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC96883.1 - 1.9e-13 50.4 0.0 3e-13 49.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMC96883.1 - 4.5e-08 32.9 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase PF07224.6 EMC96883.1 - 0.00015 20.6 0.0 0.00038 19.3 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase Thioesterase PF00975.15 EMC96883.1 - 0.00019 21.7 0.0 0.00024 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 EMC96883.1 - 0.00029 20.2 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.6 EMC96883.1 - 0.0055 15.8 0.0 1.8 7.5 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 EMC96883.1 - 0.0085 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.2 EMC96883.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 EMC96883.1 - 0.05 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) UPF0227 PF05728.7 EMC96883.1 - 0.099 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 EMC96883.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) His_Phos_2 PF00328.17 EMC96884.1 - 2.2e-14 53.5 0.0 5.3e-12 45.7 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) CorA PF01544.13 EMC96885.1 - 6.3e-41 140.3 0.0 1e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3318 PF11780.3 EMC96886.1 - 0.13 11.7 0.3 0.16 11.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) SPC12 PF06645.8 EMC96887.1 - 4.4e-28 96.8 0.1 5.5e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) zf-rbx1 PF12678.2 EMC96888.1 - 1.5e-35 121.1 13.5 1.9e-35 120.7 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC96888.1 - 3.1e-17 62.2 10.1 4.1e-17 61.8 7.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EMC96888.1 - 1.9e-07 30.7 11.8 1e-06 28.4 8.2 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC96888.1 - 0.0013 18.3 11.5 0.018 14.7 8.0 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC96888.1 - 0.0049 16.5 10.1 0.49 10.1 7.1 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC96888.1 - 0.048 13.6 12.8 1.4 9.0 9.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMC96888.1 - 0.45 10.5 9.2 2.2 8.2 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EMC96888.1 - 0.73 9.5 6.7 18 5.1 4.7 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EMC96888.1 - 0.83 9.4 11.7 6.6 6.5 8.1 2.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EMC96888.1 - 1.9 8.6 10.5 1.2e+02 2.9 7.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain PNRC PF15365.1 EMC96889.1 - 2.9e-05 23.9 3.4 2.9e-05 23.9 2.3 5.6 6 2 0 6 6 6 3 Proline-rich nuclear receptor coactivator FA_hydroxylase PF04116.8 EMC96890.1 - 3.6e-14 53.1 17.5 3.6e-14 53.1 12.2 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily PDR_CDR PF06422.7 EMC96890.1 - 1.3 8.6 8.5 14 5.4 0.0 3.2 3 0 0 3 3 3 0 CDR ABC transporter PLDc_2 PF13091.1 EMC96891.1 - 2.9e-13 49.6 0.0 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMC96891.1 - 1.4e-06 27.8 4.0 0.049 13.4 0.4 3.7 3 1 0 3 3 3 2 Phospholipase D Active site motif NDUFA12 PF05071.11 EMC96892.1 - 0.00015 22.2 0.9 0.00017 22.0 0.6 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ABC_membrane PF00664.18 EMC96893.1 - 4e-52 177.3 25.8 5.7e-28 98.1 3.0 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EMC96893.1 - 6.7e-52 175.4 0.0 5.4e-31 107.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMC96893.1 - 1.4e-10 41.6 0.0 0.015 15.2 0.0 4.4 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EMC96893.1 - 1.8e-07 30.6 2.8 0.14 11.3 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMC96893.1 - 2.7e-06 27.8 0.6 0.0016 18.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EMC96893.1 - 5.7e-06 25.8 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC96893.1 - 6.7e-05 23.0 0.1 1.1 9.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EMC96893.1 - 0.00011 21.6 0.6 0.23 10.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EMC96893.1 - 0.00013 21.4 0.2 0.37 10.1 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_17 PF13207.1 EMC96893.1 - 0.00015 22.6 0.9 0.43 11.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EMC96893.1 - 0.00015 21.8 0.5 0.8 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EMC96893.1 - 0.00015 20.7 0.0 0.038 12.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 EMC96893.1 - 0.0002 21.8 0.2 0.65 10.5 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 EMC96893.1 - 0.00022 21.1 0.0 0.058 13.1 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EMC96893.1 - 0.00025 21.0 0.2 0.19 11.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC96893.1 - 0.00031 19.9 0.0 0.26 10.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 EMC96893.1 - 0.0021 17.7 0.3 3 7.5 0.0 3.0 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EMC96893.1 - 0.0043 17.3 0.6 8.5 6.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EMC96893.1 - 0.0046 16.7 1.4 0.97 9.2 0.1 2.9 2 0 0 2 2 2 1 Dynamin family IstB_IS21 PF01695.12 EMC96893.1 - 0.0066 15.8 0.0 5.4 6.4 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 EMC96893.1 - 0.007 16.5 0.3 4.9 7.3 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EMC96893.1 - 0.013 14.5 2.9 2.3 7.2 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EMC96893.1 - 0.017 14.6 0.0 3.6 7.0 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EMC96893.1 - 0.017 14.9 0.2 3.4 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EMC96893.1 - 0.04 13.6 0.4 2.7 7.8 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 EMC96893.1 - 0.055 13.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 EMC96893.1 - 0.067 12.7 0.5 4.6 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMC96893.1 - 0.083 13.0 0.2 28 4.9 0.0 3.3 4 0 0 4 4 2 0 RNA helicase ATP-synt_ab PF00006.20 EMC96893.1 - 0.096 12.1 0.0 11 5.4 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CbiA PF01656.18 EMC96893.1 - 0.1 12.0 1.6 0.2 11.0 0.1 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EMC96893.1 - 0.12 12.0 1.3 3.4 7.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 EMC96893.1 - 0.12 12.0 3.0 15 5.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SOR_SNZ PF01680.12 EMC96895.1 - 3.6e-112 372.9 6.8 5.1e-112 372.5 4.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EMC96895.1 - 2e-06 27.0 10.7 8.3e-06 25.0 0.6 2.6 2 2 0 2 2 2 2 Thiazole biosynthesis protein ThiG NanE PF04131.9 EMC96895.1 - 9.7e-05 21.4 0.3 0.0021 17.0 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 EMC96895.1 - 0.00011 21.1 0.4 0.015 14.1 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 EMC96895.1 - 0.00051 18.9 0.1 0.0059 15.5 0.0 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IGPS PF00218.16 EMC96895.1 - 0.0019 17.2 0.2 0.015 14.3 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase MxiH PF09392.5 EMC96895.1 - 0.0021 18.6 0.7 0.016 15.7 0.0 2.5 2 2 0 2 2 2 1 Type III secretion needle MxiH like His_biosynth PF00977.16 EMC96895.1 - 0.0027 17.0 0.3 0.035 13.3 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EMC96895.1 - 0.019 14.1 0.2 0.019 14.1 0.1 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase Trp_syntA PF00290.15 EMC96895.1 - 0.042 12.3 0.0 0.069 11.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Lactamase_B PF00753.22 EMC96896.1 - 0.0038 16.8 0.0 0.0098 15.5 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Zn_clus PF00172.13 EMC96897.1 - 1.5e-09 37.6 9.7 3e-09 36.6 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC96897.1 - 2e-05 23.5 1.1 2e-05 23.5 0.8 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain TPR_19 PF14559.1 EMC96897.1 - 0.037 14.3 0.7 0.079 13.3 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC96897.1 - 0.051 13.5 1.2 0.15 12.0 0.2 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1275 PF06912.6 EMC96898.1 - 6e-42 143.2 19.0 7.3e-42 142.9 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Sugar_tr PF00083.19 EMC96899.1 - 2.8e-95 319.5 32.5 3.3e-95 319.3 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC96899.1 - 1.9e-19 69.5 32.1 1.9e-19 69.5 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.17 EMC96900.1 - 2.5e-38 131.3 0.0 3.2e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.3 EMC96901.1 - 6e-22 77.7 0.9 9.2e-22 77.1 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2-Hacid_dh_C PF02826.14 EMC96902.1 - 5.9e-39 133.0 0.0 8e-39 132.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC96902.1 - 9.5e-12 44.5 0.0 1.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC96902.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 EMC96903.1 - 3.7e-41 141.0 26.2 5.3e-41 140.5 18.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CPSF_A PF03178.10 EMC96903.1 - 0.092 11.8 0.0 0.3 10.1 0.0 1.7 1 1 0 1 1 1 0 CPSF A subunit region DUF3176 PF11374.3 EMC96904.1 - 6.3e-26 90.4 0.7 1.1e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MaoC_dehydratas PF01575.14 EMC96905.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain eRF1_2 PF03464.10 EMC96908.1 - 5e-47 159.5 0.1 8.2e-47 158.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMC96908.1 - 2.5e-39 134.0 0.4 7e-39 132.5 0.1 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 EMC96908.1 - 2.7e-28 98.1 0.0 4.7e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Aa_trans PF01490.13 EMC96909.1 - 2.4e-66 223.9 23.7 2.8e-66 223.7 16.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMC96909.1 - 0.0019 17.0 9.3 0.0019 17.0 6.4 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family HDC PF02329.11 EMC96909.1 - 0.2 10.2 0.0 4.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Histidine carboxylase PI chain PDT PF00800.13 EMC96910.1 - 4.6e-67 225.1 0.0 5.9e-67 224.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EMC96910.1 - 1.6e-05 24.2 0.0 3.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain Histone PF00125.19 EMC96911.1 - 2.6e-22 78.7 0.1 3.2e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC96911.1 - 2.3e-05 24.3 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CN_hydrolase PF00795.17 EMC96912.1 - 8e-19 67.7 0.0 1.5e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L39 PF00832.15 EMC96913.1 - 4.8e-22 77.1 9.0 5.3e-22 77.0 6.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 EMC96913.1 - 0.12 11.9 0.8 0.13 11.7 0.5 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF3429 PF11911.3 EMC96915.1 - 0.011 15.7 0.3 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) SNARE_assoc PF09335.6 EMC96915.1 - 0.18 12.0 3.0 0.28 11.3 2.0 1.4 1 1 0 1 1 1 0 SNARE associated Golgi protein MUG113 PF13455.1 EMC96916.1 - 1.1e-28 99.4 1.2 1.1e-28 99.4 0.8 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EMC96916.1 - 1.7e-22 79.6 0.2 4.8e-22 78.2 0.2 1.8 1 0 0 1 1 1 1 T5orf172 domain zf-C4pol PF14260.1 EMC96916.1 - 0.07 13.1 0.5 0.72 9.8 0.1 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta GSH_synth_ATP PF03917.12 EMC96918.1 - 1.2e-101 340.0 0.0 1.5e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EMC96918.1 - 4.8e-34 116.5 0.0 8e-34 115.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EMC96919.1 - 4.2e-42 143.9 0.0 6.4e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC96919.1 - 1.1e-13 50.8 0.0 2.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC96919.1 - 1.3e-06 28.3 0.0 3.6e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_transf_8 PF01501.15 EMC96920.1 - 9e-20 71.0 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 AAA PF00004.24 EMC96921.1 - 6.7e-41 139.5 0.0 1.2e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC96921.1 - 1.9e-07 31.2 0.2 7.4e-05 22.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMC96921.1 - 7.6e-06 25.9 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMC96921.1 - 1.2e-05 24.3 0.0 2.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EMC96921.1 - 5e-05 23.0 0.1 0.00015 21.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC96921.1 - 0.00016 21.7 0.1 0.00063 19.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EMC96921.1 - 0.00036 19.6 0.0 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EMC96921.1 - 0.0014 18.6 0.5 0.004 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EMC96921.1 - 0.0018 17.8 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMC96921.1 - 0.0031 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMC96921.1 - 0.0065 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMC96921.1 - 0.0067 16.1 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EMC96921.1 - 0.0082 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EMC96921.1 - 0.0082 16.9 1.2 0.012 16.3 0.2 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EMC96921.1 - 0.009 15.8 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMC96921.1 - 0.011 15.4 0.1 0.36 10.4 0.1 2.4 1 1 1 2 2 2 0 NACHT domain AAA_18 PF13238.1 EMC96921.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EMC96921.1 - 0.015 14.4 0.1 0.43 9.6 0.0 2.2 1 1 1 2 2 2 0 KaiC TIP49 PF06068.8 EMC96921.1 - 0.016 13.9 0.1 0.047 12.4 0.1 1.6 1 1 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 EMC96921.1 - 0.016 14.5 1.4 0.26 10.6 0.3 2.4 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 EMC96921.1 - 0.039 12.8 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EMC96921.1 - 0.043 13.0 0.3 0.21 10.7 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EMC96921.1 - 0.047 13.8 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EMC96921.1 - 0.054 12.6 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EMC96921.1 - 0.065 12.8 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EMC96921.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EMC96921.1 - 0.15 12.3 0.2 0.72 10.1 0.2 2.2 1 1 0 1 1 1 0 ABC transporter UQ_con PF00179.21 EMC96922.1 - 8.9e-41 138.6 0.0 1.2e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC96922.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC96922.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 RWD domain UBA_3 PF09288.5 EMC96922.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain U79_P34 PF03064.11 EMC96922.1 - 0.13 11.7 1.2 0.2 11.1 0.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3886 PF13025.1 EMC96922.1 - 7.6 6.5 10.5 14 5.7 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Ribosomal_L5_C PF00673.16 EMC96924.1 - 8.8e-23 79.8 0.0 1.4e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMC96924.1 - 6.9e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Hpt PF01627.18 EMC96924.1 - 0.059 13.3 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Hpt domain SAC3_GANP PF03399.11 EMC96925.1 - 2.7e-51 174.0 0.1 3.6e-51 173.6 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMC96925.1 - 0.056 13.2 0.1 0.38 10.5 0.1 2.3 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 adh_short PF00106.20 EMC96926.1 - 1.3e-15 57.7 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC96926.1 - 3.5e-08 33.5 0.0 4.8e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMC96926.1 - 0.0088 14.9 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EMC96926.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 EMC96926.1 - 0.13 12.2 0.0 1.3 9.0 0.0 2.2 2 2 0 2 2 2 0 NADH(P)-binding DUF4203 PF13886.1 EMC96928.1 - 9.4e-43 146.1 29.5 1.2e-42 145.7 20.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2423 PF10338.4 EMC96929.1 - 5.2e-15 55.1 4.9 5.2e-15 55.1 3.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.1 EMC96930.1 - 1.4e-40 138.6 0.2 2.4e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EMC96930.1 - 2.5e-17 62.1 1.4 4e-17 61.4 0.9 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EMC96930.1 - 8.7e-08 31.4 0.4 1.7e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EMC96930.1 - 2.2e-06 27.0 0.5 4e-06 26.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ABC_membrane PF00664.18 EMC96931.1 - 5.5e-76 255.6 24.7 3.6e-45 154.5 5.2 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC96931.1 - 6e-51 172.3 0.0 2.2e-30 105.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC96931.1 - 6.6e-09 35.3 4.3 0.0019 17.4 0.1 4.1 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC96931.1 - 2.5e-05 24.3 1.6 0.27 11.2 0.3 3.0 3 0 0 3 3 3 2 AAA ATPase domain Miro PF08477.8 EMC96931.1 - 2.7e-05 24.6 0.6 1.1 9.8 0.0 3.8 3 0 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 EMC96931.1 - 6.7e-05 22.8 1.0 0.26 11.2 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMC96931.1 - 0.00016 20.9 0.2 0.051 12.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMC96931.1 - 0.00035 20.0 0.3 1 8.9 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 EMC96931.1 - 0.0014 18.5 1.3 0.096 12.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 EMC96931.1 - 0.0016 18.5 0.1 15 5.4 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.1 EMC96931.1 - 0.0023 17.3 0.0 0.84 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EMC96931.1 - 0.0051 16.6 1.2 1.3 8.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 EMC96931.1 - 0.014 14.9 2.1 6.5 6.2 0.1 3.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMC96931.1 - 0.014 15.6 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMC96931.1 - 0.023 14.1 0.1 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 EMC96931.1 - 0.04 13.0 0.0 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 EMC96931.1 - 0.082 12.3 0.1 7.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMC96931.1 - 0.22 11.6 2.3 14 5.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain DUF2841 PF11001.3 EMC96933.1 - 1.5e-26 92.6 0.3 2.7e-26 91.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Dioxygenase_C PF00775.16 EMC96934.1 - 4.1e-48 163.0 0.0 5.8e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EMC96934.1 - 5.5e-13 48.6 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EMC96934.1 - 0.018 15.1 0.0 0.13 12.3 0.0 2.4 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EMC96934.1 - 0.029 14.1 0.0 0.081 12.7 0.0 1.8 1 0 0 1 1 1 0 Cna protein B-type domain Dehyd-heme_bind PF09098.5 EMC96934.1 - 0.054 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Cu_amine_oxid PF01179.15 EMC96935.1 - 8.8e-171 568.1 0.1 1.1e-170 567.9 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EMC96935.1 - 4.8e-21 74.7 0.7 4e-20 71.7 0.0 2.5 2 1 1 3 3 3 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EMC96935.1 - 7e-12 45.2 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sulfatase PF00884.18 EMC96936.1 - 4.4e-76 256.0 0.0 5.5e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMC96936.1 - 0.00024 21.3 0.1 0.011 15.9 0.0 2.6 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EMC96936.1 - 0.015 14.6 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMC96936.1 - 0.13 10.6 0.0 0.22 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) BAR PF03114.13 EMC96937.1 - 1.6e-42 145.5 8.2 8.5e-39 133.4 1.3 2.1 2 0 0 2 2 2 2 BAR domain KfrA_N PF11740.3 EMC96937.1 - 0.035 14.5 1.7 0.14 12.6 0.1 2.3 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term BAR_2 PF10455.4 EMC96937.1 - 0.071 12.0 0.1 0.16 10.8 0.0 1.8 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2884 PF11101.3 EMC96937.1 - 0.92 8.8 4.6 5.8 6.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Arfaptin PF06456.8 EMC96937.1 - 0.98 8.7 5.7 0.45 9.8 1.3 2.1 2 1 0 2 2 2 0 Arfaptin-like domain Peptidase_M22 PF00814.20 EMC96938.1 - 1.9e-85 286.6 0.0 2.2e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family TOM13 PF08219.6 EMC96938.1 - 0.0057 16.3 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 2 Outer membrane protein TOM13 DUF3479 PF11965.3 EMC96939.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Cut8_N PF14482.1 EMC96939.1 - 0.93 9.5 7.9 0.073 13.0 1.0 2.5 2 2 0 2 2 2 0 Cut8 proteasome-binding domain ACOX PF01756.14 EMC96940.1 - 1e-36 126.1 0.3 2.1e-36 125.0 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EMC96940.1 - 3.4e-26 92.0 0.1 8.6e-26 90.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EMC96940.1 - 5.6e-12 44.9 2.6 1.4e-11 43.6 0.2 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMC96940.1 - 1.6e-07 31.5 0.3 0.0068 16.5 0.0 2.8 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Ndc1_Nup PF09531.5 EMC96941.1 - 7.5e-111 371.4 5.4 2.1e-110 369.9 3.7 1.6 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EMC96942.1 - 1.5e-23 82.7 0.7 1.5e-23 82.7 0.5 2.9 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EMC96942.1 - 7e-18 64.0 6.5 7e-18 64.0 4.5 2.2 3 0 0 3 3 3 1 SNARE domain Synaptobrevin PF00957.16 EMC96942.1 - 0.00081 18.9 0.3 0.00081 18.9 0.2 2.0 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.16 EMC96942.1 - 0.0038 16.7 6.2 0.14 11.6 2.5 2.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2580 PF10824.3 EMC96942.1 - 0.0041 17.4 3.1 0.0087 16.3 0.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2580) DUF3523 PF12037.3 EMC96942.1 - 0.055 12.4 11.3 0.11 11.4 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF912 PF06024.7 EMC96942.1 - 0.093 12.7 0.1 0.093 12.7 0.1 2.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_US9 PF06072.6 EMC96942.1 - 0.12 12.2 0.2 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Prominin PF05478.6 EMC96942.1 - 0.66 7.4 6.4 0.15 9.5 0.4 2.0 1 1 1 2 2 2 0 Prominin Spectrin PF00435.16 EMC96942.1 - 2.4 8.5 10.2 15 5.9 6.1 2.7 1 1 1 2 2 2 0 Spectrin repeat Peptidase_S64 PF08192.6 EMC96942.1 - 2.8 6.1 6.7 4.2 5.5 4.6 1.3 1 1 0 1 1 1 0 Peptidase family S64 Laminin_II PF06009.7 EMC96942.1 - 3.3 7.4 10.4 1.4 8.6 0.5 3.1 2 1 1 3 3 3 0 Laminin Domain II Epimerase PF01370.16 EMC96944.1 - 1.5e-16 60.5 0.0 2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC96944.1 - 1.4e-12 47.9 0.3 2.6e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC96944.1 - 3.1e-11 42.9 0.2 4.6e-11 42.4 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EMC96944.1 - 1.5e-09 37.0 0.0 2.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMC96944.1 - 9.4e-09 34.5 0.0 5.7e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMC96944.1 - 4.3e-07 29.1 0.1 6.9e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMC96944.1 - 5.7e-07 29.6 0.8 1.7e-06 28.0 0.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC96944.1 - 0.00081 19.1 0.3 0.0023 17.6 0.2 1.8 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 EMC96944.1 - 0.015 15.2 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EMC96944.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tcf25 PF04910.9 EMC96945.1 - 9.6e-73 245.1 0.1 1.6e-72 244.4 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Nop53 PF07767.6 EMC96945.1 - 0.14 11.1 14.1 0.28 10.1 9.7 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAA_hydrolase PF01557.13 EMC96946.1 - 3e-58 196.8 0.0 4.6e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 EMC96946.1 - 1.4e-32 113.4 0.0 2.3e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC96946.1 - 1.5e-15 57.1 0.0 4.3e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC96946.1 - 2e-15 56.9 0.1 8e-14 51.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Amidohydro_1 PF01979.15 EMC96946.1 - 4e-10 39.8 0.4 1.2e-09 38.3 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMC96946.1 - 1.2e-07 31.4 0.0 7.7e-07 28.8 0.0 2.5 1 0 0 1 1 1 1 Amidohydrolase PGAP1 PF07819.8 EMC96946.1 - 5.2e-06 26.2 0.0 9.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Amidohydro_4 PF13147.1 EMC96946.1 - 7.9e-06 26.1 3.1 3e-05 24.1 1.0 2.6 2 1 0 2 2 1 1 Amidohydrolase Ser_hydrolase PF06821.8 EMC96946.1 - 8.8e-05 22.1 0.0 0.00063 19.3 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.3 EMC96946.1 - 0.00025 20.8 0.1 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Amidohydro_3 PF07969.6 EMC96946.1 - 0.0011 18.2 1.0 0.0021 17.3 0.2 1.8 1 1 0 2 2 2 1 Amidohydrolase family DUF900 PF05990.7 EMC96946.1 - 0.0016 17.8 0.0 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Ndr PF03096.9 EMC96946.1 - 0.0023 16.4 0.0 0.0038 15.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family LCAT PF02450.10 EMC96946.1 - 0.0044 16.0 0.3 0.014 14.3 0.0 2.0 3 0 0 3 3 3 1 Lecithin:cholesterol acyltransferase Abhydrolase_8 PF06259.7 EMC96946.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2305 PF10230.4 EMC96946.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Aa_trans PF01490.13 EMC96947.1 - 3.8e-43 147.5 33.1 4.9e-43 147.1 22.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMC96947.1 - 0.0012 17.7 19.3 0.0012 17.7 13.4 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4212 PF13937.1 EMC96947.1 - 0.094 12.7 10.3 2.1 8.3 0.3 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4212) AhpC-TSA PF00578.16 EMC96948.1 - 1.4e-24 86.1 0.0 2.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMC96948.1 - 2.4e-16 59.5 0.0 3.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EMC96948.1 - 0.0012 18.6 0.0 0.0039 17.1 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ribosomal_L30 PF00327.15 EMC96950.1 - 0.042 13.4 0.2 0.11 12.1 0.2 1.6 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e UCH_1 PF13423.1 EMC96952.1 - 3.3e-63 213.8 0.0 8.4e-63 212.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EMC96952.1 - 3.6e-16 59.0 0.0 8.2e-16 57.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.22 EMC96953.1 - 4.2e-69 228.3 1.9 4.4e-23 80.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4440 PF14534.1 EMC96954.1 - 0.029 14.5 0.2 0.037 14.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) RBFA PF02033.13 EMC96954.1 - 0.064 13.2 0.3 9.4 6.3 0.0 2.9 2 2 1 3 3 3 0 Ribosome-binding factor A Peptidase_S9 PF00326.16 EMC96955.1 - 7.2e-37 126.6 0.0 1.2e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC96955.1 - 1.4e-11 44.3 0.2 2.8e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC96955.1 - 3.2e-08 33.7 5.4 1.5e-07 31.5 3.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EMC96955.1 - 1.1e-06 28.0 1.3 0.05 12.7 0.0 2.4 2 0 0 2 2 2 2 Secretory lipase Peptidase_S15 PF02129.13 EMC96955.1 - 6.9e-06 25.6 0.4 1.1e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.7 EMC96955.1 - 8.3e-06 25.3 0.0 0.0069 16.0 0.1 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DLH PF01738.13 EMC96955.1 - 0.00096 18.4 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EMC96955.1 - 0.0015 18.1 0.0 0.0042 16.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EMC96955.1 - 0.045 12.2 0.1 0.46 8.9 0.1 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 EMC96955.1 - 0.053 13.3 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase CH PF00307.26 EMC96956.1 - 1.1e-38 131.5 0.2 4.7e-18 65.2 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EMC96956.1 - 1e-25 89.4 0.0 2.6e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EMC96956.1 - 2.9e-09 36.4 0.8 0.00073 19.1 0.0 3.4 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_8 PF13833.1 EMC96956.1 - 0.0025 17.4 0.1 0.053 13.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC96956.1 - 0.0076 16.0 0.1 0.092 12.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EMC96956.1 - 0.02 14.1 0.1 0.74 9.2 0.0 2.7 2 0 0 2 2 2 0 EF hand EMP24_GP25L PF01105.19 EMC96956.1 - 0.02 14.6 0.1 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD EF-hand_7 PF13499.1 EMC96956.1 - 0.037 14.1 0.2 0.19 11.9 0.2 2.3 1 0 0 1 1 1 0 EF-hand domain pair Spectrin PF00435.16 EMC96956.1 - 0.055 13.7 7.8 0.027 14.7 1.6 2.9 3 0 0 3 3 3 0 Spectrin repeat DUF2884 PF11101.3 EMC96956.1 - 0.11 11.8 5.8 1.6 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) PBD PF00786.23 EMC96957.1 - 0.015 15.6 0.2 0.06 13.7 0.1 2.1 1 0 0 1 1 1 0 P21-Rho-binding domain NmrA PF05368.8 EMC96959.1 - 1.5e-34 119.2 0.0 2e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC96959.1 - 2.2e-13 50.6 0.0 3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMC96959.1 - 5e-05 22.3 0.0 0.00022 20.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMC96959.1 - 0.0034 17.3 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.16 EMC96959.1 - 0.0039 16.6 0.0 0.086 12.2 0.0 2.5 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EMC96959.1 - 0.0054 17.1 0.8 0.92 9.9 0.0 3.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EMC96959.1 - 0.025 14.8 0.1 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMC96959.1 - 0.058 13.3 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EMC96959.1 - 0.1 11.4 0.0 3.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 EMC96959.1 - 0.13 11.9 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 KR domain WD40 PF00400.27 EMC96961.1 - 3.3e-23 80.6 14.1 4.5e-06 26.3 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat MraZ PF02381.13 EMC96961.1 - 0.0016 18.1 0.0 0.61 9.8 0.0 2.5 2 0 0 2 2 2 2 MraZ protein DUF2457 PF10446.4 EMC96961.1 - 0.1 11.3 19.7 0.18 10.5 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EMC96961.1 - 0.44 9.7 15.0 0.69 9.1 10.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EMC96961.1 - 0.89 7.3 15.7 1.4 6.7 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EMC96961.1 - 1.2 8.0 11.0 2.2 7.2 7.7 1.3 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.6 EMC96961.1 - 1.3 7.0 4.9 1.7 6.6 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 EMC96961.1 - 2.1 6.7 10.3 3.6 5.9 7.1 1.3 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 EMC96961.1 - 2.9 7.5 15.9 6 6.5 11.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L23eN PF03939.8 EMC96962.1 - 1.3e-20 73.1 8.5 2.6e-20 72.1 5.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EMC96962.1 - 2e-15 56.4 0.6 2e-15 56.4 0.4 1.8 2 1 0 2 2 2 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.10 EMC96963.1 - 9.3e-23 79.2 2.2 1.1e-22 79.0 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger NAP PF00956.13 EMC96964.1 - 4.9e-84 281.2 12.2 4.9e-84 281.2 8.5 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) UFD1 PF03152.9 EMC96965.1 - 4.2e-73 244.2 0.0 5.3e-73 243.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EMC96965.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 DUF3321 PF11968.3 EMC96966.1 - 9.7e-89 296.7 0.0 1.3e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EMC96966.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABC2_membrane_3 PF12698.2 EMC96967.1 - 3.4 6.6 13.1 4.2 6.3 9.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RNA_pol_I_A49 PF06870.7 EMC96968.1 - 1.1e-63 215.1 0.0 1.3e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Nitrate_red_del PF02613.10 EMC96968.1 - 0.039 13.7 0.1 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Nitrate reductase delta subunit Tub_2 PF04525.7 EMC96970.1 - 9.1e-08 31.7 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Tubby C 2 DUF676 PF05057.9 EMC96971.1 - 8e-06 25.3 0.0 9.7e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EMC96971.1 - 0.00037 20.2 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMC96971.1 - 0.00057 19.5 0.0 0.00091 18.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EMC96971.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EMC96971.1 - 0.019 14.5 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Ank_4 PF13637.1 EMC96972.1 - 1.5e-18 66.8 0.0 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC96972.1 - 1.9e-16 60.1 0.0 2.4e-08 34.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC96972.1 - 8.6e-16 56.8 1.4 9.7e-07 28.3 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EMC96972.1 - 6.9e-14 50.5 0.1 2.1e-06 27.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC96972.1 - 3.2e-12 46.2 0.1 1.7e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF4480 PF13715.1 EMC96972.1 - 0.019 14.9 0.0 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4480) Ank_2 PF12796.2 EMC96973.1 - 1.8e-14 53.8 0.2 6.3e-12 45.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC96973.1 - 1.3e-13 49.9 1.7 4.4e-05 23.0 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMC96973.1 - 1.8e-11 43.8 0.4 1.6e-08 34.4 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC96973.1 - 1.1e-10 41.6 1.2 3.4e-09 36.9 0.1 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC96973.1 - 4.4e-08 32.6 0.1 0.042 14.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat MFS_1 PF07690.11 EMC96974.1 - 5e-31 107.7 41.8 5e-31 107.7 29.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PhyH PF05721.8 EMC96978.1 - 6.5e-10 39.4 0.1 1.7e-09 38.0 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DNA_binding_1 PF01035.15 EMC96979.1 - 9.8e-22 76.5 0.0 1.2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DinB_2 PF12867.2 EMC96979.1 - 0.14 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 DinB superfamily DUF2039 PF10217.4 EMC96982.1 - 0.019 15.0 0.2 0.036 14.0 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) K-cyclin_vir_C PF09080.5 EMC96983.1 - 8.1 6.7 10.2 1.3 9.2 2.8 2.1 2 0 0 2 2 2 0 K cyclin, C terminal Pet127 PF08634.5 EMC96984.1 - 1.4e-115 385.1 0.3 1.8e-115 384.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 ARD PF03079.9 EMC96985.1 - 3.2e-46 157.1 0.0 3.8e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EMC96985.1 - 1.4e-09 37.3 0.1 2.1e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EMC96985.1 - 1.4e-05 24.7 0.1 2.2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EMC96985.1 - 0.00024 20.5 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EMC96985.1 - 0.027 14.0 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 EMC96985.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) HPP PF04982.8 EMC96986.1 - 1.2e-35 121.9 10.1 1.2e-35 121.9 7.0 1.9 2 0 0 2 2 2 1 HPP family ORC2 PF04084.9 EMC96987.1 - 2.7e-99 332.1 0.0 3.4e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AMPKBI PF04739.10 EMC96987.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Nop14 PF04147.7 EMC96987.1 - 1.6 6.5 5.8 2.2 6.1 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family Adenylsucc_synt PF00709.16 EMC96989.1 - 8.3e-157 522.1 0.0 9.4e-157 521.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Pho88 PF10032.4 EMC96990.1 - 1.5e-84 282.0 0.2 1.7e-84 281.8 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) SecG PF03840.9 EMC96990.1 - 0.52 10.0 3.4 5.4 6.8 0.2 2.4 2 0 0 2 2 2 0 Preprotein translocase SecG subunit MBOAT PF03062.14 EMC96991.1 - 1.6e-44 152.3 6.1 3.5e-44 151.2 4.2 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family ATP-cone PF03477.11 EMC96991.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP cone domain Bac_rhamnosid PF05592.6 EMC96992.1 - 1.3e-33 115.9 5.8 2.8e-30 105.0 2.5 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Cyclin_N PF00134.18 EMC96993.1 - 7.9e-08 31.9 0.1 1.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain F-box PF00646.28 EMC96994.1 - 0.00013 21.5 0.6 0.00032 20.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMC96994.1 - 0.0091 15.7 0.8 0.033 13.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like 2-Hacid_dh_C PF02826.14 EMC96995.1 - 2.3e-50 170.1 0.0 3.8e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC96995.1 - 9.3e-35 118.9 0.0 1.2e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC96995.1 - 7.4e-05 22.6 0.5 0.00024 20.9 0.1 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EMC96995.1 - 0.0012 18.6 0.3 0.0036 17.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EMC96995.1 - 0.0058 16.0 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain IlvN PF07991.7 EMC96995.1 - 0.006 15.9 0.4 0.064 12.6 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 EMC96995.1 - 0.066 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain 4HBT PF03061.17 EMC96997.1 - 1e-05 25.5 0.2 4.8e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 Thioesterase superfamily Exo_endo_phos PF03372.18 EMC96998.1 - 4.9e-20 72.5 0.1 8.9e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.8 EMC96999.1 - 1.7e-23 82.9 0.0 2.2e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Init_tRNA_PT PF04179.7 EMC97001.1 - 6.9e-142 473.4 0.0 8e-142 473.2 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Radical_SAM PF04055.16 EMC97002.1 - 3.6e-16 59.7 0.0 8.6e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EMC97002.1 - 2.9e-10 40.0 0.1 8.1e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Cut8_N PF14482.1 EMC97003.1 - 0.071 13.1 9.1 0.51 10.3 1.0 3.6 3 1 0 3 3 3 0 Cut8 proteasome-binding domain Lipoxygenase PF00305.14 EMC97003.1 - 0.83 7.5 2.9 1 7.2 0.1 2.0 2 0 0 2 2 2 0 Lipoxygenase NPR3 PF03666.8 EMC97006.1 - 0.53 8.7 2.8 0.66 8.4 1.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dicty_REP PF05086.7 EMC97006.1 - 0.69 7.5 5.3 0.76 7.4 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein His_biosynth PF00977.16 EMC97007.1 - 1.9e-29 102.5 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EMC97007.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EMC97008.1 - 1.3e-06 28.4 2.4 2.9e-06 27.3 1.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) VGLL4 PF15245.1 EMC97008.1 - 0.083 12.7 0.8 0.12 12.2 0.1 1.5 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 STE PF02200.11 EMC97010.1 - 2.6e-61 204.5 0.2 4.2e-61 203.9 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EMC97010.1 - 7.7e-10 38.5 10.9 0.00014 22.0 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC97010.1 - 1.1e-08 34.7 9.4 0.0007 19.7 1.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC97010.1 - 6.2e-08 32.5 3.1 6.2e-08 32.5 2.1 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMC97010.1 - 0.00013 21.7 0.2 0.00052 19.8 0.2 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.2 EMC97010.1 - 0.052 13.7 2.6 0.32 11.2 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC97010.1 - 0.12 12.5 0.3 0.12 12.5 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding WD40 PF00400.27 EMC97011.1 - 1.1e-36 123.3 15.9 9.2e-10 38.0 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.7 EMC97011.1 - 1.3e-35 122.6 5.3 1.3e-35 122.6 3.7 1.7 2 0 0 2 2 2 1 Striatin family DUF4613 PF15390.1 EMC97011.1 - 8.6 4.4 5.9 5.8 4.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) Rhabdo_ncap PF00945.13 EMC97012.1 - 0.026 13.1 1.8 0.033 12.8 0.3 1.7 1 1 1 2 2 2 0 Rhabdovirus nucleocapsid protein IER PF05760.7 EMC97012.1 - 0.031 14.2 0.4 0.035 14.0 0.3 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Atrophin-1 PF03154.10 EMC97012.1 - 2.2 6.3 4.3 2.5 6.1 3.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family ADH_zinc_N PF00107.21 EMC97013.1 - 1.1e-12 47.6 0.0 1.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC97013.1 - 3.7e-05 24.6 0.0 4.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC97014.1 - 9.6e-21 73.5 2.3 1.3e-20 73.1 1.6 1.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn60_TCP1 PF00118.19 EMC97015.1 - 1.6e-119 399.6 8.7 6.9e-119 397.6 6.0 1.8 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.15 EMC97015.1 - 0.054 13.6 0.2 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 Transcriptional regulator UPRTase PF14681.1 EMC97017.1 - 5.8e-81 270.6 0.0 9.1e-81 269.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EMC97017.1 - 8.8e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Retinal PF15449.1 EMC97019.1 - 0.067 10.8 1.2 0.067 10.8 0.9 1.0 1 0 0 1 1 1 0 Retinal protein WAPL PF07814.8 EMC97020.1 - 1.3e-13 50.4 3.7 1.5e-09 37.1 0.1 2.4 1 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin DUF383 PF04063.9 EMC97020.1 - 0.038 13.5 0.1 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF383) DUF3405 PF11885.3 EMC97021.1 - 2.5e-208 692.3 0.1 2.9e-208 692.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DAO PF01266.19 EMC97021.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Formyl_trans_N PF00551.14 EMC97023.1 - 2.2e-26 92.4 0.0 3e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Peptidase_C78 PF07910.8 EMC97024.1 - 5.1e-47 159.8 0.0 8.9e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EMC97024.1 - 0.014 15.5 0.2 0.014 15.5 0.1 2.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RFX_DNA_binding PF02257.10 EMC97029.1 - 1.8e-30 104.8 0.0 5.1e-30 103.4 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Med15 PF09606.5 EMC97029.1 - 0.1 10.7 74.2 0.47 8.5 36.1 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TB2_DP1_HVA22 PF03134.14 EMC97030.1 - 8.6e-32 108.7 6.5 1.2e-31 108.2 4.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Sec8_exocyst PF04048.9 EMC97031.1 - 1.1e-43 148.3 0.1 2.7e-43 147.0 0.1 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EMC97031.1 - 1.3e-08 34.0 0.1 2.6e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EMC97031.1 - 0.039 12.1 0.2 0.064 11.4 0.1 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 TPR_11 PF13414.1 EMC97032.1 - 4.4e-32 109.5 21.0 1.2e-06 28.0 0.0 10.6 7 2 3 11 11 11 9 TPR repeat TPR_12 PF13424.1 EMC97032.1 - 2.8e-25 88.0 23.8 5.1e-08 32.7 0.1 9.2 5 3 6 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMC97032.1 - 3.2e-22 76.6 22.3 0.0067 16.2 0.0 12.5 12 1 1 13 13 13 5 Tetratricopeptide repeat TPR_1 PF00515.23 EMC97032.1 - 6.7e-22 76.1 8.5 0.025 14.1 0.0 11.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC97032.1 - 2.2e-18 66.3 25.8 0.00011 22.4 0.0 9.3 7 2 1 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EMC97032.1 - 1.1e-13 51.4 38.1 6.8e-06 26.6 0.2 12.6 7 3 7 14 14 14 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC97032.1 - 8.3e-13 47.1 12.9 0.98 9.3 0.0 11.7 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC97032.1 - 1.9e-12 46.3 12.5 3.6 8.0 0.0 11.5 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC97032.1 - 2.4e-12 46.4 23.2 0.0017 18.7 0.0 11.2 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC97032.1 - 2.6e-12 46.2 39.4 0.00024 21.4 0.1 13.1 13 3 3 16 16 13 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC97032.1 - 1.2e-10 40.3 22.6 0.31 10.9 0.0 10.7 12 1 1 13 13 12 4 Tetratricopeptide repeat Apc3 PF12895.2 EMC97032.1 - 1.8e-05 24.7 5.1 0.99 9.5 0.0 6.5 7 0 0 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EMC97032.1 - 0.00012 21.9 1.1 22 5.0 0.0 5.4 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EMC97032.1 - 0.0018 18.1 23.8 1.2 9.1 0.2 9.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC97032.1 - 0.0063 16.3 19.7 0.62 9.9 0.1 6.8 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMC97032.1 - 0.07 13.5 11.0 12 6.6 0.0 6.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TSP_1 PF00090.14 EMC97034.1 - 0.053 13.6 0.1 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 Thrombospondin type 1 domain MIT PF04212.13 EMC97035.1 - 2.7e-26 91.2 6.6 4.9e-14 51.9 1.6 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EMC97035.1 - 0.00011 21.7 0.8 0.45 10.2 0.0 2.8 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EMC97035.1 - 0.00019 21.2 0.5 0.9 9.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_5 PF12688.2 EMC97035.1 - 0.00031 20.7 0.2 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 Tetratrico peptide repeat TPR_2 PF07719.12 EMC97035.1 - 0.00051 19.7 2.3 0.98 9.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC97035.1 - 0.0017 18.0 5.5 0.53 10.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC97035.1 - 0.0019 18.0 1.7 0.35 10.8 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Rootletin PF15035.1 EMC97035.1 - 0.032 14.2 1.9 0.44 10.4 0.1 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TPR_3 PF07720.7 EMC97035.1 - 0.07 12.9 1.8 1.7 8.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC97035.1 - 0.12 11.9 3.7 1.1 9.0 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat COX7C PF02935.11 EMC97036.1 - 6.2e-16 57.9 2.2 7e-16 57.7 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CoA_binding PF02629.14 EMC97037.1 - 1.7e-28 98.9 2.5 1.1e-27 96.3 0.3 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EMC97037.1 - 7.5e-23 80.8 0.1 1.2e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EMC97037.1 - 5.1e-08 32.6 0.0 8.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EMC97037.1 - 0.0002 21.4 0.0 0.00048 20.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 EMC97037.1 - 0.0012 19.4 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.20 EMC97038.1 - 1.4e-33 116.2 4.8 1.4e-33 116.2 3.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97038.1 - 3.5e-26 92.4 1.1 4.1e-26 92.2 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97038.1 - 1.1e-17 64.3 3.5 1.3e-17 64.0 2.2 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMC97038.1 - 8.5e-05 22.2 0.1 0.00015 21.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EMC97038.1 - 0.0011 18.7 0.3 0.0019 18.0 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EMC97038.1 - 0.0014 17.5 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMC97038.1 - 0.0026 17.8 1.9 0.0059 16.6 1.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMC97038.1 - 0.0064 15.2 0.1 0.011 14.4 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.10 EMC97038.1 - 0.012 15.2 0.2 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.13 EMC97038.1 - 0.013 15.5 0.1 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EMC97038.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 EMC97038.1 - 0.022 14.3 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Semialdhyde_dh PF01118.19 EMC97038.1 - 0.04 14.2 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EMC97038.1 - 0.057 12.3 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 EMC97038.1 - 0.057 12.5 0.1 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMC97038.1 - 0.059 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.21 EMC97038.1 - 0.073 12.6 0.7 0.31 10.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EMC97038.1 - 0.12 12.9 0.5 0.3 11.6 0.2 1.8 2 1 0 2 2 2 0 Methyltransferase domain AAA PF00004.24 EMC97039.1 - 4.8e-17 62.3 0.0 8.3e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EMC97039.1 - 9.7e-15 54.3 0.0 2.1e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EMC97039.1 - 5.9e-14 52.0 0.1 1.6e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EMC97039.1 - 6.9e-12 44.8 0.0 1.1e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EMC97039.1 - 3.9e-07 30.2 0.2 2e-06 27.9 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.1 EMC97039.1 - 4.1e-07 29.7 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC97039.1 - 7.6e-07 29.2 0.0 1.1e-05 25.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EMC97039.1 - 1.8e-06 27.6 0.3 7.9e-06 25.6 0.1 2.1 1 1 2 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EMC97039.1 - 4.1e-06 26.4 0.0 9.4e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 EMC97039.1 - 9.2e-06 25.2 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 EMC97039.1 - 9.4e-06 25.3 0.5 0.0012 18.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EMC97039.1 - 3.6e-05 23.6 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC97039.1 - 3.8e-05 22.8 0.0 0.00011 21.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EMC97039.1 - 7.6e-05 21.5 0.0 0.27 9.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 EMC97039.1 - 8.3e-05 21.6 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EMC97039.1 - 9.6e-05 22.0 0.1 0.00043 19.9 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EMC97039.1 - 0.00012 21.7 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EMC97039.1 - 0.00021 20.4 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EMC97039.1 - 0.00093 18.7 0.2 0.011 15.2 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 EMC97039.1 - 0.0012 18.1 0.2 0.42 9.8 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.21 EMC97039.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMC97039.1 - 0.002 17.5 0.0 0.3 10.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 EMC97039.1 - 0.0029 17.6 0.0 0.006 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC97039.1 - 0.0035 16.7 0.1 0.017 14.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain TK PF00265.13 EMC97039.1 - 0.0041 16.6 0.1 0.0085 15.6 0.0 1.4 1 1 0 1 1 1 1 Thymidine kinase ResIII PF04851.10 EMC97039.1 - 0.0048 16.7 0.0 0.36 10.6 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EMC97039.1 - 0.0098 15.0 0.1 0.099 11.7 0.1 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMC97039.1 - 0.013 16.2 0.0 0.025 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMC97039.1 - 0.015 14.7 0.2 1.5 8.1 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain SNF2_N PF00176.18 EMC97039.1 - 0.02 13.6 0.0 0.84 8.3 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 EMC97039.1 - 0.023 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EMC97039.1 - 0.023 14.9 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC97039.1 - 0.027 14.6 0.0 0.061 13.4 0.0 1.6 1 1 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EMC97039.1 - 0.041 13.3 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EMC97039.1 - 0.048 13.9 0.0 0.099 12.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Herpes_UL56 PF04534.7 EMC97039.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein Sec1 PF00995.18 EMC97040.1 - 1.2e-152 509.4 0.0 1.4e-152 509.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family NAD_binding_8 PF13450.1 EMC97041.1 - 6.1e-08 32.5 0.3 1.1e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMC97041.1 - 1.5e-05 24.3 0.0 5.4e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EMC97041.1 - 4.9e-05 22.5 1.3 4.9e-05 22.5 0.9 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC97041.1 - 6.3e-05 22.9 0.7 0.00046 20.1 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC97041.1 - 7.6e-05 21.7 2.3 0.00012 21.0 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMC97041.1 - 0.00014 21.0 0.6 0.00024 20.2 0.4 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EMC97041.1 - 0.00015 20.4 0.6 0.00025 19.6 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EMC97041.1 - 0.00025 20.0 2.1 0.0012 17.8 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EMC97041.1 - 0.0014 17.5 0.4 0.0047 15.8 0.3 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMC97041.1 - 0.0097 14.8 0.1 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EMC97041.1 - 0.011 14.7 0.2 0.016 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EMC97041.1 - 0.015 15.3 0.3 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase VirC1 PF07015.6 EMC97041.1 - 0.057 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Pyr_redox PF00070.22 EMC97041.1 - 0.076 13.4 0.4 0.16 12.4 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BON PF04972.12 EMC97041.1 - 0.086 12.6 0.4 0.23 11.2 0.2 1.7 1 0 0 1 1 1 0 BON domain Trp_halogenase PF04820.9 EMC97041.1 - 0.16 10.5 0.8 0.24 10.0 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.11 EMC97042.1 - 6.1e-35 120.5 41.3 6.1e-35 120.5 28.6 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EMC97044.1 - 1.1e-36 126.3 0.0 1.6e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 V-ATPase_H_C PF11698.3 EMC97044.1 - 0.069 13.0 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 V-ATPase subunit H BURP PF03181.10 EMC97046.1 - 0.0083 15.3 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 BURP domain Mem_trans PF03547.13 EMC97047.1 - 0.12 10.6 0.2 0.13 10.5 0.2 1.0 1 0 0 1 1 1 0 Membrane transport protein IKI3 PF04762.7 EMC97050.1 - 1.3e-286 953.1 0.1 6.3e-152 507.4 0.0 2.2 1 1 1 2 2 2 2 IKI3 family H-kinase_dim PF02895.9 EMC97050.1 - 0.0092 16.2 0.1 2.4 8.5 0.0 2.6 2 0 0 2 2 2 2 Signal transducing histidine kinase, homodimeric domain Apc4_WD40 PF12894.2 EMC97050.1 - 0.027 13.9 0.0 0.086 12.3 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain PSK_trans_fac PF07704.6 EMC97050.1 - 0.13 12.9 0.3 0.13 12.9 0.2 2.6 3 0 0 3 3 3 0 Rv0623-like transcription factor HhH-GPD PF00730.20 EMC97051.1 - 8.6e-15 54.9 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UCR_14kD PF02271.11 EMC97052.1 - 6.8e-45 151.1 0.1 8e-45 150.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EMC97053.1 - 3.1e-68 225.5 1.4 7.6e-24 83.2 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein SAP PF02037.22 EMC97054.1 - 0.025 14.0 0.2 0.51 9.8 0.0 2.8 3 0 0 3 3 3 0 SAP domain LEM PF03020.10 EMC97054.1 - 0.059 12.8 0.0 0.7 9.3 0.0 2.6 2 0 0 2 2 2 0 LEM domain Nucleoporin_C PF03177.9 EMC97055.1 - 1.8e-65 221.5 15.2 1.8e-65 221.5 10.5 1.4 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EMC97055.1 - 4.4e-34 117.9 0.0 6e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like RGS PF00615.14 EMC97058.1 - 1.2e-30 105.9 0.0 2.6e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EMC97058.1 - 1.3e-23 82.4 0.0 1.9e-19 69.1 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 EMC97059.1 - 4.6e-57 193.1 0.0 6.6e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97059.1 - 1.5e-21 76.6 0.0 2.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC97059.1 - 2.9e-06 26.4 0.0 5.3e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC97059.1 - 0.16 11.0 0.0 0.7 8.9 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EMC97060.1 - 2e-35 122.1 0.1 4.1e-35 121.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97060.1 - 1.7e-14 53.5 0.0 2.3e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC97060.1 - 0.0047 16.6 0.2 0.2 11.3 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family CIAPIN1 PF05093.8 EMC97061.1 - 1.2e-34 118.3 4.4 2.2e-34 117.5 3.0 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis His_Phos_2 PF00328.17 EMC97062.1 - 5.7e-08 32.4 0.0 4.8e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TRI12 PF06609.8 EMC97063.1 - 1.2e-24 86.4 31.2 1.5e-24 86.1 21.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMC97063.1 - 4.4e-16 58.5 66.2 7.3e-16 57.8 42.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_76 PF03663.9 EMC97064.1 - 8e-39 134.0 22.0 1e-38 133.6 15.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glug PF07581.7 EMC97064.1 - 0.67 10.2 3.3 2.3 8.6 0.1 2.7 2 0 0 2 2 2 0 The GLUG motif NAD_binding_10 PF13460.1 EMC97065.1 - 1.9e-07 31.2 0.0 4.3e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMC97065.1 - 2e-05 24.1 0.0 6.1e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMC97065.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.20 EMC97066.1 - 2.7e-09 37.1 1.2 4.6e-09 36.4 0.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97066.1 - 4.7e-07 29.8 0.1 6e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC97066.1 - 8.1e-06 25.4 0.3 1.5e-05 24.5 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC97066.1 - 2.3e-05 24.4 0.6 0.00017 21.6 0.1 2.0 1 1 2 3 3 3 1 NADH(P)-binding NmrA PF05368.8 EMC97066.1 - 0.00061 19.1 0.2 0.0011 18.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EMC97066.1 - 0.0023 17.5 0.3 0.0097 15.5 0.2 2.0 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EMC97066.1 - 0.0069 15.3 0.1 0.0099 14.7 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EMC97066.1 - 0.03 14.7 0.1 0.28 11.6 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EMC97066.1 - 0.035 13.7 0.1 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMC97066.1 - 0.04 13.0 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 EMC97066.1 - 0.042 13.4 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pyr_redox_2 PF07992.9 EMC97066.1 - 0.061 13.1 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC97066.1 - 0.078 11.8 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Troponin-I_N PF11636.3 EMC97067.1 - 0.92 9.2 4.2 21 4.9 0.3 2.7 2 0 0 2 2 2 0 Troponin I residues 1-32 Nol1_Nop2_Fmu PF01189.12 EMC97068.1 - 4.4e-98 328.1 0.0 6e-98 327.6 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EMC97068.1 - 0.027 14.4 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EMC97068.1 - 0.032 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Met_10 PF02475.11 EMC97068.1 - 0.08 12.5 0.2 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein Abhydrolase_3 PF07859.8 EMC97069.1 - 9.4e-43 146.2 0.0 1.3e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC97069.1 - 0.00035 19.8 0.0 0.00097 18.4 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EMC97069.1 - 0.0017 17.0 0.0 0.0024 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EMC97069.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_5 PF12695.2 EMC97069.1 - 0.075 12.7 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family STE3 PF02076.10 EMC97070.1 - 9.4e-78 261.1 19.3 1.2e-77 260.8 13.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor UDPG_MGDP_dh_N PF03721.9 EMC97071.1 - 1e-47 161.8 0.0 2.1e-46 157.6 0.0 2.1 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EMC97071.1 - 3.9e-32 110.3 0.0 8e-32 109.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EMC97071.1 - 2.1e-25 88.9 0.0 1.3e-20 73.5 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Saccharop_dh PF03435.13 EMC97071.1 - 9.8e-05 21.4 0.1 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 EMC97071.1 - 0.0073 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMC97071.1 - 0.022 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMC97071.1 - 0.033 13.9 0.0 0.57 9.9 0.0 2.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glycos_transf_1 PF00534.15 EMC97072.1 - 1.3e-37 128.8 0.0 1.8e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMC97072.1 - 9.7e-15 54.9 0.0 2.1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMC97072.1 - 1.2e-09 38.3 0.0 2.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMC97072.1 - 2.8e-06 27.5 0.0 5.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EMC97072.1 - 0.0004 20.1 0.0 0.0053 16.4 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 DUF3090 PF11290.3 EMC97072.1 - 0.028 13.8 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Pkinase PF00069.20 EMC97075.1 - 7.6e-68 228.4 0.0 1.4e-67 227.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97075.1 - 2.7e-52 177.3 0.0 5.2e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMC97075.1 - 9.7e-20 70.7 0.0 2.9e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 EMC97075.1 - 1.1e-06 28.7 0.2 2.4e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EMC97075.1 - 1.8e-05 23.8 0.0 3.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EMC97075.1 - 0.0044 17.2 0.7 0.031 14.5 0.5 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 EMC97075.1 - 0.069 12.8 3.6 0.16 11.6 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family PH_9 PF15410.1 EMC97075.1 - 0.099 12.8 3.8 9.8 6.3 0.3 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain adh_short PF00106.20 EMC97077.1 - 3.3e-12 46.6 2.7 3.3e-11 43.3 1.9 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97077.1 - 0.00011 22.0 0.0 0.00043 20.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97077.1 - 0.00058 19.5 2.3 0.022 14.4 1.6 2.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC97077.1 - 0.00083 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMC97077.1 - 0.034 13.9 0.5 0.081 12.7 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMC97077.1 - 0.037 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Methyltransf_26 PF13659.1 EMC97077.1 - 0.13 12.2 0.1 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 EMC97078.1 - 1e-09 37.4 0.0 2.6e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 Rer1 PF03248.8 EMC97079.1 - 0.46 10.0 4.7 0.65 9.5 3.3 1.2 1 0 0 1 1 1 0 Rer1 family DUF2838 PF10998.3 EMC97079.1 - 0.6 10.0 7.0 0.81 9.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) AMPKBI PF04739.10 EMC97080.1 - 6.1e-28 96.6 1.9 6.2e-28 96.6 0.0 2.0 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF3460 PF11943.3 EMC97080.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Fungal_trans_2 PF11951.3 EMC97082.1 - 3.4e-05 22.6 0.1 5e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CopD PF05425.8 EMC97083.1 - 7.6 6.8 10.4 2.5 8.3 0.9 3.1 3 0 0 3 3 3 0 Copper resistance protein D PAN_3 PF08277.7 EMC97084.1 - 4.8e-08 32.4 9.7 0.00088 18.8 0.6 2.9 2 0 0 2 2 2 2 PAN-like domain PAN_4 PF14295.1 EMC97084.1 - 0.034 13.8 1.1 0.034 13.8 0.8 4.2 4 0 0 4 4 4 0 PAN domain zf-RING_3 PF14369.1 EMC97084.1 - 0.11 12.5 14.4 0.13 12.2 1.2 4.0 3 0 0 3 3 3 0 zinc-finger ABC_membrane PF00664.18 EMC97085.1 - 1.9e-91 306.3 40.6 4.5e-48 164.0 10.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC97085.1 - 3.9e-67 224.7 0.0 9.2e-33 113.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC97085.1 - 2.6e-14 53.0 0.0 6.4e-05 22.2 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC97085.1 - 1.7e-10 41.3 0.1 0.45 10.4 0.0 4.3 3 1 0 4 4 4 4 AAA domain DUF258 PF03193.11 EMC97085.1 - 2.9e-08 33.0 0.0 0.066 12.3 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EMC97085.1 - 1.3e-07 30.5 2.7 0.0015 17.2 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMC97085.1 - 2.8e-07 30.6 0.9 0.0033 17.4 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 EMC97085.1 - 6.5e-07 28.7 5.8 0.00066 19.1 0.2 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMC97085.1 - 1.1e-06 29.4 0.0 0.056 14.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC97085.1 - 3.2e-05 24.0 1.0 0.61 10.2 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMC97085.1 - 0.00028 20.3 0.6 1 8.6 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.1 EMC97085.1 - 0.00073 19.1 3.5 1.4 8.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.12 EMC97085.1 - 0.0014 18.4 0.2 0.35 10.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EMC97085.1 - 0.0019 17.6 0.8 11 5.3 0.1 4.1 4 0 0 4 4 4 0 AAA-like domain AAA_33 PF13671.1 EMC97085.1 - 0.0029 17.4 0.2 3.4 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMC97085.1 - 0.0031 17.4 0.5 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC97085.1 - 0.004 17.4 0.0 4.9 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EMC97085.1 - 0.017 13.8 0.0 1.4 7.5 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.9 EMC97085.1 - 0.018 14.7 0.5 10 5.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EMC97085.1 - 0.019 14.4 0.8 4.5 6.7 0.0 3.5 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EMC97085.1 - 0.024 14.5 0.0 5.1 6.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain DUF815 PF05673.8 EMC97085.1 - 0.037 12.9 0.0 2.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.15 EMC97085.1 - 0.042 13.5 1.0 0.64 9.6 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_23 PF13476.1 EMC97085.1 - 0.043 14.1 0.0 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMC97085.1 - 0.045 13.6 8.3 1 9.3 0.3 3.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EMC97085.1 - 0.048 13.3 0.1 8.2 6.1 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EMC97085.1 - 0.059 13.1 1.7 2.4 7.9 0.2 3.1 2 0 0 2 2 2 0 Part of AAA domain PRK PF00485.13 EMC97085.1 - 0.08 12.4 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EMC97085.1 - 0.13 12.4 0.4 11 6.2 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Cache_3 PF14827.1 EMC97085.1 - 0.4 10.6 4.0 14 5.5 0.2 3.4 3 0 0 3 3 3 0 Sensory domain of two-component sensor kinase MMR_HSR1 PF01926.18 EMC97085.1 - 1.7 8.6 4.0 11 6.0 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF3169 PF11368.3 EMC97087.1 - 0.047 12.9 0.8 0.07 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Methyltransf_31 PF13847.1 EMC97088.1 - 2.1e-20 72.8 0.0 3.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC97088.1 - 2e-16 60.2 0.0 4.4e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC97088.1 - 5.1e-15 55.7 0.1 1.4e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC97088.1 - 1.6e-13 51.2 0.1 4.3e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC97088.1 - 3.8e-13 49.0 0.0 6.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMC97088.1 - 2.4e-12 47.1 0.0 6.9e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC97088.1 - 4.6e-11 42.6 0.0 7.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC97088.1 - 1.3e-09 37.9 0.1 4e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EMC97088.1 - 3.6e-08 33.4 0.3 1.3e-07 31.6 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC97088.1 - 2.4e-07 30.2 0.0 4.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EMC97088.1 - 1.4e-05 25.1 0.2 2.7e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase UPF0020 PF01170.13 EMC97088.1 - 0.00014 21.4 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 EMC97088.1 - 0.00022 20.3 0.0 0.0017 17.4 0.0 2.3 3 1 0 3 3 3 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EMC97088.1 - 0.00029 19.6 0.0 0.00043 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.15 EMC97088.1 - 0.00058 18.9 0.0 0.00093 18.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GCD14 PF08704.5 EMC97088.1 - 0.0049 16.4 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.12 EMC97088.1 - 0.0049 15.9 0.0 0.009 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FmrO PF07091.6 EMC97088.1 - 0.0057 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 EMC97088.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.8 EMC97088.1 - 0.013 14.6 0.3 0.022 13.9 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 EMC97088.1 - 0.041 12.5 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_3 PF01596.12 EMC97088.1 - 0.055 12.5 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DREV PF05219.7 EMC97088.1 - 0.067 12.0 0.0 0.15 10.9 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase ADH_zinc_N PF00107.21 EMC97088.1 - 0.092 12.2 0.8 0.19 11.2 0.2 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase CheR PF01739.13 EMC97088.1 - 0.11 11.8 0.0 0.45 9.7 0.0 1.9 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DUF410 PF04190.8 EMC97089.1 - 1.6e-58 198.2 0.0 2e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Fungal_trans PF04082.13 EMC97090.1 - 7.7e-10 38.0 0.2 1.4e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC97090.1 - 6.8e-08 32.3 5.2 1.1e-07 31.5 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF1 PF04857.15 EMC97092.1 - 4.4e-55 186.8 0.0 6.4e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 EMC97094.1 - 1.2e-13 50.5 0.8 2.7e-13 49.4 0.2 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family KGG PF10685.4 EMC97095.1 - 0.045 13.7 4.0 0.045 13.7 2.8 3.0 3 0 0 3 3 3 0 Stress-induced bacterial acidophilic repeat motif Aminotran_1_2 PF00155.16 EMC97096.1 - 4.4e-83 279.2 0.0 5.6e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMC97096.1 - 8.6e-06 24.7 0.0 2.1e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMC97096.1 - 0.00017 19.9 0.0 0.00031 19.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMC97096.1 - 0.0079 15.2 0.2 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Tho2 PF11262.3 EMC97097.1 - 9.4e-68 228.4 0.0 1.5e-67 227.7 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EMC97097.1 - 9.5e-27 92.6 0.1 5.7e-26 90.1 0.0 2.5 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Thioredoxin PF00085.15 EMC97098.1 - 3.3e-06 26.7 0.2 8.5e-06 25.3 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMC97098.1 - 0.00027 21.0 0.1 0.00033 20.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain DnaJ PF00226.26 EMC97099.1 - 1.8e-24 85.2 2.4 3e-24 84.5 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMC97099.1 - 9.7e-23 79.8 2.9 8.2e-21 73.6 0.1 2.8 2 1 0 2 2 2 2 DnaJ C terminal domain RAI1 PF08652.6 EMC97100.1 - 2.6e-23 81.5 0.0 4.7e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease adh_short PF00106.20 EMC97101.1 - 2.1e-12 47.2 0.0 4.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC97101.1 - 1.9e-05 24.3 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Toxin_38 PF14866.1 EMC97102.1 - 0.018 15.0 3.5 0.049 13.7 2.4 1.7 1 0 0 1 1 1 0 Potassium channel toxin LTV PF04180.9 EMC97103.1 - 7.8e-73 246.3 9.0 2.3e-71 241.5 6.3 2.8 1 1 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 EMC97104.1 - 2.1e-18 66.3 0.2 9.8e-16 57.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC97104.1 - 1.1e-06 28.0 0.2 2.8e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EMC97104.1 - 0.00015 20.9 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EMC97104.1 - 0.0038 17.0 3.3 0.051 13.4 0.0 3.0 3 0 0 3 3 3 1 Dynamin family AIG1 PF04548.11 EMC97104.1 - 0.0088 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EMC97104.1 - 0.045 14.2 0.1 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EMC97104.1 - 0.069 12.5 0.2 2.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NOA36 PF06524.7 EMC97104.1 - 8.7 5.5 10.9 14 4.7 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein zinc_ribbon_6 PF14599.1 EMC97106.1 - 2.5e-17 62.3 1.2 1.3e-13 50.5 0.0 5.1 4 1 1 5 5 5 2 Zinc-ribbon zf-CHY PF05495.7 EMC97106.1 - 1e-12 48.0 23.1 1e-12 48.0 16.0 3.9 4 0 0 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EMC97106.1 - 1.7e-09 37.3 4.1 1.7e-09 37.3 2.8 4.2 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC97106.1 - 1.4e-06 28.2 3.4 1.4e-06 28.2 2.4 5.2 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC97106.1 - 1.2e-05 24.8 10.2 1.2e-05 24.8 7.1 5.4 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC97106.1 - 0.0013 18.3 12.5 0.0013 18.3 8.7 6.1 2 2 3 5 5 5 1 zinc-RING finger domain Acyl_transf_1 PF00698.16 EMC97108.1 - 5.7e-22 78.4 0.0 2.5e-19 69.7 0.0 2.1 1 1 0 1 1 1 1 Acyl transferase domain ELFV_dehydrog PF00208.16 EMC97109.1 - 1.1e-86 290.3 2.8 1.4e-86 290.0 2.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EMC97109.1 - 1.2e-49 167.1 0.0 2.5e-49 166.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EMC97109.1 - 0.0047 17.1 0.6 0.015 15.5 0.1 2.1 3 0 0 3 3 3 1 Putative NAD(P)-binding UbiA PF01040.13 EMC97111.1 - 1.9e-31 109.1 24.7 2.6e-31 108.7 17.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PNGaseA PF12222.3 EMC97115.1 - 4e-145 483.9 7.7 5.5e-145 483.4 5.3 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A JmjC PF02373.17 EMC97117.1 - 1.1e-09 38.4 1.1 9.5e-09 35.5 0.8 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EMC97117.1 - 1.4e-05 24.4 0.1 0.0031 16.9 0.0 2.7 2 0 0 2 2 2 2 Cupin domain zf-4CXXC_R1 PF10497.4 EMC97117.1 - 0.00029 20.9 6.5 0.00029 20.9 4.5 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_5 PF14634.1 EMC97119.1 - 0.0002 21.0 3.2 0.00075 19.1 2.3 1.9 1 1 0 1 1 1 1 zinc-RING finger domain Fer4_13 PF13370.1 EMC97119.1 - 0.021 15.2 1.6 0.76 10.2 0.0 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF3153 PF11353.3 EMC97119.1 - 0.075 12.4 0.1 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) ATP-synt_E PF05680.7 EMC97119.1 - 4.2 7.3 6.7 7.4 6.6 4.6 1.3 1 0 0 1 1 1 0 ATP synthase E chain adh_short PF00106.20 EMC97121.1 - 5.7e-31 107.6 0.3 8.6e-31 107.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97121.1 - 5.9e-25 88.4 0.5 3.6e-23 82.5 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97121.1 - 5.7e-17 61.9 0.3 9e-17 61.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC97121.1 - 1.1e-05 25.0 0.1 3.1e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Meth_synt_2 PF01717.13 EMC97123.1 - 4.9e-143 475.9 0.0 8.5e-138 458.7 0.0 2.5 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMC97123.1 - 4.4e-125 417.0 0.0 1.5e-114 382.4 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EMC97123.1 - 0.0018 17.2 0.0 0.33 9.8 0.0 2.5 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.4 EMC97123.1 - 0.17 11.4 3.6 0.077 12.4 0.2 2.3 2 0 0 2 2 2 0 Short C-terminal domain CCDC155 PF14662.1 EMC97123.1 - 0.24 10.9 2.5 0.18 11.3 0.2 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 CbbQ_C PF08406.5 EMC97124.1 - 0.096 12.7 0.4 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal HECT PF00632.20 EMC97125.1 - 4.4e-89 298.7 0.0 6.2e-89 298.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMC97125.1 - 5.1e-32 109.3 15.4 6.9e-11 41.7 1.2 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EMC97125.1 - 2.9e-15 55.8 0.2 6.6e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain Septin PF00735.13 EMC97126.1 - 2.7e-111 371.1 0.4 3.3e-111 370.8 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMC97126.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EMC97126.1 - 2.7e-05 23.3 0.0 5.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EMC97126.1 - 3.9e-05 23.1 0.1 0.021 14.2 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMC97126.1 - 7e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EMC97126.1 - 0.00065 19.5 0.5 0.73 9.6 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EMC97126.1 - 0.0021 17.5 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EMC97126.1 - 0.0085 15.0 0.0 0.037 12.9 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Gtr1_RagA PF04670.7 EMC97126.1 - 0.018 14.2 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EMC97126.1 - 0.019 15.1 0.0 0.052 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC97126.1 - 0.02 15.1 1.1 0.036 14.3 0.7 1.8 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EMC97126.1 - 0.021 14.7 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMC97126.1 - 0.023 14.1 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EMC97126.1 - 0.029 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 EMC97126.1 - 0.036 14.3 0.0 0.067 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC97126.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.18 EMC97127.1 - 1.8e-12 47.2 7.5 2e-12 47.0 5.2 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.1 EMC97127.1 - 1.5 8.1 5.7 5.3 6.3 4.0 1.8 1 1 0 1 1 1 0 zinc-ribbon domain WD40 PF00400.27 EMC97128.1 - 1.8e-25 87.8 6.1 7.2e-10 38.3 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMC97128.1 - 0.037 12.3 0.1 1.3 7.2 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Hira PF07569.6 EMC97128.1 - 0.065 12.4 0.4 0.17 11.0 0.1 1.8 2 0 0 2 2 2 0 TUP1-like enhancer of split tRNA-synt_1g PF09334.6 EMC97130.1 - 3e-144 480.4 0.0 4.3e-144 479.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMC97130.1 - 2.1e-09 35.9 0.5 1.6e-05 23.1 0.0 3.5 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMC97130.1 - 0.026 14.2 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Laminin_EGF PF00053.19 EMC97130.1 - 0.26 11.2 3.5 0.56 10.1 2.4 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Yae1_N PF09811.4 EMC97131.1 - 9.7e-10 37.8 3.4 9.7e-10 37.8 2.3 1.5 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Rad52_Rad22 PF04098.10 EMC97132.1 - 2.8e-62 208.9 0.1 4.9e-62 208.2 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Peptidase_S10 PF00450.17 EMC97133.1 - 2.1e-114 382.9 0.0 3.2e-114 382.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase CM_2 PF01817.16 EMC97133.1 - 0.04 13.9 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Chorismate mutase type II Herpes_gE PF02480.11 EMC97133.1 - 0.19 9.9 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ank_2 PF12796.2 EMC97134.1 - 2.8e-31 107.6 3.8 2.4e-08 34.1 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC97134.1 - 1e-24 85.9 11.1 3.9e-06 26.9 1.7 5.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EMC97134.1 - 2.3e-23 80.7 9.5 0.00027 20.5 0.2 8.4 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EMC97134.1 - 5.1e-22 77.8 9.0 3.8e-07 30.4 0.6 5.6 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC97134.1 - 8.4e-19 65.8 4.2 0.0033 17.5 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat CorA PF01544.13 EMC97134.1 - 1.4e-10 40.6 0.6 1.2e-09 37.6 0.1 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Imm38 PF15599.1 EMC97136.1 - 0.061 12.8 4.0 0.081 12.4 2.8 1.3 1 0 0 1 1 1 0 Immunity protein 38 DUF1609 PF07753.6 EMC97136.1 - 0.097 11.9 5.4 0.12 11.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Bap31 PF05529.7 EMC97136.1 - 0.11 11.9 2.5 0.13 11.7 1.7 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ADIP PF11559.3 EMC97136.1 - 0.45 10.3 8.5 0.9 9.4 5.9 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2072 PF09845.4 EMC97136.1 - 0.5 10.2 6.1 0.69 9.8 4.2 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) IncA PF04156.9 EMC97136.1 - 0.52 9.8 3.0 0.58 9.7 2.1 1.2 1 0 0 1 1 1 0 IncA protein QH-AmDH_gamma PF08992.6 EMC97136.1 - 0.8 9.5 6.4 2.1 8.1 0.2 2.7 1 1 2 3 3 3 0 Quinohemoprotein amine dehydrogenase, gamma subunit DDRGK PF09756.4 EMC97136.1 - 1.7 8.0 13.5 2 7.7 9.4 1.1 1 0 0 1 1 1 0 DDRGK domain DUF724 PF05266.9 EMC97136.1 - 4.3 6.9 9.3 6.2 6.3 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran PF00005.22 EMC97137.1 - 1.3e-47 161.5 0.0 7e-23 81.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EMC97137.1 - 7.7e-22 76.9 3.1 7.7e-22 76.9 2.2 2.5 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EMC97137.1 - 8.4e-21 75.1 2.6 1.7e-05 24.9 0.1 4.3 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 EMC97137.1 - 1.2e-10 40.9 0.2 0.14 11.3 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMC97137.1 - 2e-09 36.8 0.1 0.00067 19.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EMC97137.1 - 5.3e-08 33.4 7.0 0.039 14.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 EMC97137.1 - 1.6e-07 30.6 0.1 0.00025 20.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMC97137.1 - 3.6e-06 27.2 0.2 0.013 15.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EMC97137.1 - 8.3e-06 26.6 0.1 0.11 13.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EMC97137.1 - 8.4e-06 25.9 0.0 0.056 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EMC97137.1 - 1.2e-05 24.6 0.0 0.033 13.2 0.0 3.4 4 1 0 4 4 4 2 AAA ATPase domain Miro PF08477.8 EMC97137.1 - 4.5e-05 23.9 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EMC97137.1 - 0.00011 22.3 0.2 0.26 11.2 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 EMC97137.1 - 0.00018 21.2 0.2 0.56 9.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EMC97137.1 - 0.00019 21.3 0.0 0.36 10.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EMC97137.1 - 0.00059 19.6 2.0 1.9 8.1 0.0 3.5 3 1 0 4 4 4 2 Archaeal ATPase AAA PF00004.24 EMC97137.1 - 0.00063 19.9 0.0 0.72 10.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMC97137.1 - 0.00079 19.5 0.5 2.2 8.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.1 EMC97137.1 - 0.0017 18.2 0.1 1.4 8.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EMC97137.1 - 0.0019 18.1 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMC97137.1 - 0.0036 17.2 0.0 2.2 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMC97137.1 - 0.0039 16.9 0.1 2.2 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EMC97137.1 - 0.0042 15.9 0.0 1.5 7.6 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 EMC97137.1 - 0.0088 15.4 0.0 1.4 8.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EMC97137.1 - 0.012 15.5 0.5 0.83 9.6 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EMC97137.1 - 0.013 13.9 2.3 11 4.3 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EMC97137.1 - 0.014 14.8 0.2 4.9 6.5 0.1 2.7 3 0 0 3 3 2 0 AAA-like domain MobB PF03205.9 EMC97137.1 - 0.018 14.7 1.1 0.23 11.1 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 EMC97137.1 - 0.018 13.6 0.0 5.7 5.4 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DAP3 PF10236.4 EMC97137.1 - 0.027 13.4 0.0 3.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.17 EMC97137.1 - 0.028 13.7 0.0 6.8 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras family VirE PF05272.6 EMC97137.1 - 0.033 13.6 0.1 1.9 7.9 0.0 2.7 3 0 0 3 3 3 0 Virulence-associated protein E DUF2813 PF11398.3 EMC97137.1 - 0.036 13.1 0.0 6.3 5.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) PduV-EutP PF10662.4 EMC97137.1 - 0.043 13.3 0.2 2.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EMC97137.1 - 0.09 12.5 1.8 19 5.0 0.0 3.5 3 1 1 4 4 4 0 Dynamin family Skp1 PF01466.14 EMC97138.1 - 2.2e-39 133.3 2.5 3.9e-39 132.5 1.7 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EMC97138.1 - 5.6e-22 77.6 0.2 1.2e-21 76.5 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EMC97138.1 - 0.088 12.8 1.1 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ank_2 PF12796.2 EMC97141.1 - 4.3e-78 257.7 6.1 2.2e-19 69.5 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMC97141.1 - 4.5e-50 165.0 12.8 3.7e-07 29.6 0.1 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 EMC97141.1 - 1.7e-32 110.6 3.4 3.1e-06 27.2 0.1 7.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC97141.1 - 8.3e-31 105.8 7.8 2.2e-07 31.1 0.0 8.7 2 1 7 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC97141.1 - 3.5e-24 82.4 11.0 0.019 15.1 0.0 9.3 10 0 0 10 10 9 7 Ankyrin repeat NACHT PF05729.7 EMC97141.1 - 1.3e-11 44.4 0.0 2.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMC97141.1 - 2.2e-06 27.7 0.0 1.7e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC97141.1 - 4.9e-05 23.4 0.0 0.00043 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EMC97141.1 - 0.004 16.0 0.0 0.0069 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 EMC97141.1 - 0.0099 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2435 PF10363.4 EMC97141.1 - 0.011 15.6 0.2 0.46 10.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) RNA_helicase PF00910.17 EMC97141.1 - 0.037 14.1 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EMC97141.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Hemolysin_N PF12563.3 EMC97141.1 - 0.078 12.3 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Hemolytic toxin N terminal CCDC-167 PF15188.1 EMC97141.1 - 0.14 12.0 1.2 2 8.4 0.2 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 zf-C2H2_4 PF13894.1 EMC97142.1 - 0.46 10.9 9.2 0.16 12.3 4.5 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_2 PF13347.1 EMC97143.1 - 6.3e-14 51.2 7.9 6.3e-14 51.2 5.5 2.8 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.11 EMC97143.1 - 8.3e-10 37.8 12.4 8.3e-10 37.8 8.6 3.5 2 1 1 4 4 4 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMC97143.1 - 0.059 13.3 5.2 2.3 8.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) TMEM125 PF15109.1 EMC97143.1 - 0.08 13.0 0.4 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 TMEM125 protein family YfzA PF14118.1 EMC97143.1 - 0.1 12.7 2.0 0.62 10.2 0.0 2.8 2 0 0 2 2 2 0 YfzA-like protein Na_H_Exchanger PF00999.16 EMC97144.1 - 9.2e-67 225.1 41.5 1.1e-66 224.9 28.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NmrA PF05368.8 EMC97145.1 - 9.3e-29 100.3 0.0 2.1e-28 99.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC97145.1 - 1.1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EMC97145.1 - 5.1e-05 23.2 0.0 9.4e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EMC97145.1 - 0.00063 19.2 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC97145.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cofilin_ADF PF00241.15 EMC97147.1 - 4.7e-32 110.5 0.0 5.9e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Lactamase_B_2 PF12706.2 EMC97149.1 - 3.4e-38 131.1 0.0 4.4e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC97149.1 - 3.4e-14 52.8 0.0 5.5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC97149.1 - 0.015 14.9 4.8 1.2 8.7 2.8 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily POM121 PF15229.1 EMC97149.1 - 0.19 11.0 1.2 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 POM121 family Myb_DNA-binding PF00249.26 EMC97151.1 - 9.8e-18 63.9 0.0 1e-08 35.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Red1 PF07964.6 EMC97151.1 - 6.5 4.7 14.9 0.15 10.1 5.5 1.7 2 0 0 2 2 2 0 Rec10 / Red1 DS PF01916.12 EMC97152.1 - 2.4e-144 479.9 0.0 2.8e-144 479.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EMC97152.1 - 0.0052 15.9 0.1 0.012 14.8 0.0 1.5 2 0 0 2 2 2 1 Carbamoyltransferase MORN PF02493.15 EMC97153.1 - 3e-15 54.9 23.4 4.4e-06 26.1 0.4 4.8 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 EMC97153.1 - 2e-12 46.5 7.7 2e-12 46.5 5.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 EMC97153.1 - 1e-06 28.1 0.0 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_2 PF13923.1 EMC97153.1 - 8.3e-05 22.5 10.3 8.3e-05 22.5 7.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MATH PF00917.21 EMC97153.1 - 0.0024 18.0 0.0 0.033 14.4 0.0 2.3 1 1 0 1 1 1 1 MATH domain zf-RING_5 PF14634.1 EMC97153.1 - 0.025 14.2 9.6 0.059 13.0 6.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DUF2039 PF10217.4 EMC97153.1 - 0.069 13.1 4.0 0.18 11.8 2.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Prok-RING_4 PF14447.1 EMC97153.1 - 0.25 10.9 5.5 0.63 9.6 3.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cut12 PF11500.3 EMC97154.1 - 1.2e-13 51.0 9.4 4.9e-13 49.0 6.5 1.9 1 1 0 1 1 1 1 Spindle pole body formation-associated protein DUF2570 PF10828.3 EMC97154.1 - 0.11 12.1 2.9 0.25 10.9 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Pkinase PF00069.20 EMC97155.1 - 1.2e-61 208.1 0.0 7.8e-37 126.8 0.0 4.6 4 0 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.2 EMC97155.1 - 1.5e-36 125.9 3.1 1.5e-36 125.9 2.1 2.7 2 1 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 EMC97155.1 - 3.5e-34 118.0 0.0 1.1e-17 63.9 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EMC97155.1 - 1.4e-16 60.4 0.1 1.4e-16 60.4 0.1 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 EMC97155.1 - 1.9e-16 59.9 0.0 6.9e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 RWD domain APH PF01636.18 EMC97155.1 - 0.00094 18.9 4.1 0.00098 18.9 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC97155.1 - 0.0086 15.0 0.0 0.31 9.9 0.0 2.8 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.20 EMC97156.1 - 8.4e-61 205.3 0.0 1.1e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97156.1 - 9.5e-31 106.8 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC97156.1 - 1.8e-06 27.1 0.0 3.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC97156.1 - 9.3e-05 21.5 0.0 0.00018 20.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC97156.1 - 0.00034 20.4 0.0 0.0058 16.3 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC97156.1 - 0.0081 15.5 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DUF2917 PF11142.3 EMC97156.1 - 0.072 12.2 0.2 0.4 9.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2917) Myosin_head PF00063.16 EMC97157.1 - 1.4e-238 793.4 0.0 1.4e-238 793.4 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EMC97157.1 - 1.2e-34 118.3 4.1 3e-34 117.0 2.3 2.2 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 EMC97157.1 - 8.1e-11 40.5 39.6 0.00042 19.7 0.3 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EMC97157.1 - 0.00012 22.2 0.0 0.00047 20.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 EMC97157.1 - 0.003 16.8 1.6 0.0059 15.8 1.1 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_19 PF13245.1 EMC97157.1 - 0.021 14.5 0.0 0.075 12.7 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EMC97157.1 - 0.022 14.1 0.2 0.11 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA-like domain Myosin_tail_1 PF01576.14 EMC97157.1 - 0.078 10.6 28.2 0.25 9.0 10.3 2.1 1 1 1 2 2 2 0 Myosin tail KaiC PF06745.8 EMC97157.1 - 0.17 10.9 2.5 9.5 5.2 0.0 2.7 2 0 0 2 2 2 0 KaiC Fez1 PF06818.10 EMC97157.1 - 0.31 11.0 30.5 0.15 12.0 15.9 2.7 2 1 0 2 2 2 0 Fez1 Rab5-bind PF09311.6 EMC97157.1 - 1.2 9.0 26.1 1.8 8.4 11.1 3.0 1 1 1 2 2 2 0 Rabaptin-like protein IncA PF04156.9 EMC97157.1 - 1.4 8.4 28.4 7.2e+02 -0.4 19.6 2.6 1 1 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 EMC97157.1 - 6 6.9 11.7 1.7 8.7 4.3 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Myb_DNA-bind_6 PF13921.1 EMC97158.1 - 0.00054 20.0 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMC97158.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.6 EMC97159.1 - 1.1e-24 86.2 13.0 1.1e-24 86.2 9.0 6.8 5 1 2 7 7 7 2 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EMC97159.1 - 1e-08 35.0 9.3 1.7e-08 34.3 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC97159.1 - 7.1e-08 31.9 7.4 1.3e-07 31.1 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC97159.1 - 9.5e-08 31.5 9.0 1.7e-07 30.7 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC97159.1 - 4.3e-07 29.6 7.4 7.6e-07 28.8 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMC97159.1 - 2.5e-05 23.9 8.9 4.3e-05 23.1 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC97159.1 - 4.7e-05 23.0 5.9 4.7e-05 23.0 4.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC97159.1 - 0.0005 19.8 7.4 0.00088 19.1 5.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EMC97159.1 - 0.0024 17.9 3.6 0.0054 16.8 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EMC97159.1 - 0.0033 16.9 5.0 0.0086 15.6 3.6 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain GAS PF13851.1 EMC97159.1 - 0.0047 16.1 13.7 0.0047 16.1 9.5 6.3 3 1 2 6 6 6 2 Growth-arrest specific micro-tubule binding Rootletin PF15035.1 EMC97159.1 - 0.0057 16.6 74.6 0.01 15.8 2.4 7.1 2 2 2 5 5 5 3 Ciliary rootlet component, centrosome cohesion Rad50_zn_hook PF04423.9 EMC97159.1 - 0.013 14.9 1.1 9.5 5.7 0.0 4.6 3 0 0 3 3 3 0 Rad50 zinc hook motif Metal_resist PF13801.1 EMC97159.1 - 0.023 14.6 1.2 0.023 14.6 0.8 6.8 7 1 1 8 8 6 0 Heavy-metal resistance DZR PF12773.2 EMC97159.1 - 0.1 12.4 7.7 1.3 8.8 5.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.1 EMC97159.1 - 0.12 12.1 4.1 0.26 11.1 2.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein NADH-G_4Fe-4S_3 PF10588.4 EMC97159.1 - 0.19 11.0 1.9 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zinc-ribbons_6 PF07191.7 EMC97159.1 - 0.33 10.7 5.3 1.9 8.3 3.8 2.0 1 1 0 1 1 1 0 zinc-ribbons FYVE PF01363.16 EMC97159.1 - 0.77 9.6 8.4 4.6 7.2 5.8 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 EMC97159.1 - 1.1 8.8 6.9 0.91 9.0 2.4 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Yip1 PF04893.12 EMC97160.1 - 0.011 15.1 0.4 0.014 14.9 0.3 1.1 1 0 0 1 1 1 0 Yip1 domain Cation_efflux PF01545.16 EMC97162.1 - 2.7e-30 105.4 8.6 3.3e-30 105.1 6.0 1.1 1 0 0 1 1 1 1 Cation efflux family Rootletin PF15035.1 EMC97162.1 - 0.087 12.8 0.3 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PHBC_N PF12551.3 EMC97162.1 - 0.087 12.3 0.7 0.19 11.2 0.5 1.5 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal Pkinase PF00069.20 EMC97163.1 - 1.4e-16 60.4 0.0 1.7e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97163.1 - 8.5e-09 34.8 0.0 4.7e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase SMI1_KNR4 PF09346.5 EMC97165.1 - 2.5e-36 124.5 0.0 4.2e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) F-box-like PF12937.2 EMC97166.1 - 0.00021 20.9 0.1 0.00065 19.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC97166.1 - 0.003 17.1 0.0 0.0088 15.6 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMC97167.1 - 0.044 13.4 2.4 0.19 11.4 0.5 2.2 2 0 0 2 2 2 0 F-box-like US22 PF02393.11 EMC97169.1 - 0.071 13.1 0.1 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 US22 like MRP-S33 PF08293.6 EMC97170.1 - 1.9e-26 91.8 0.0 2.1e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.21 EMC97171.1 - 4.8e-16 59.2 0.0 8.4e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMC97171.1 - 3.5e-15 56.1 0.0 5.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Pkinase PF00069.20 EMC97172.1 - 1.6e-61 207.7 0.0 3.6e-61 206.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97172.1 - 7.2e-37 126.8 0.1 3.2e-35 121.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC97172.1 - 1.6e-09 37.1 0.0 1.2e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC97172.1 - 0.0019 18.0 0.0 0.009 15.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMC97172.1 - 0.41 9.3 0.0 0.67 8.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sybindin PF04099.7 EMC97173.1 - 3.3e-22 78.7 0.0 4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EMC97173.1 - 0.06 13.2 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region MBOAT_2 PF13813.1 EMC97175.1 - 2.7e-20 72.2 0.9 9.4e-20 70.4 0.6 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TGS PF02824.16 EMC97176.1 - 5.7e-21 74.1 0.1 9.9e-21 73.3 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMC97176.1 - 1e-18 67.3 0.2 6.5e-18 64.7 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC97176.1 - 7.8e-13 47.9 0.0 1.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMC97176.1 - 0.00027 20.8 0.3 0.34 10.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EMC97176.1 - 0.0036 17.7 0.1 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EMC97176.1 - 0.03 13.1 0.2 0.12 11.1 0.1 2.0 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 EMC97176.1 - 0.066 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AIG1 PF04548.11 EMC97176.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.1 EMC97176.1 - 0.13 12.3 0.3 1.5 8.9 0.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMC97176.1 - 0.16 12.7 0.4 0.73 10.6 0.3 2.3 1 1 0 1 1 1 0 AAA domain AIRS_C PF02769.17 EMC97177.1 - 3.9e-25 88.6 0.0 6.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EMC97177.1 - 1.3e-17 63.8 2.2 3.8e-17 62.3 0.8 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.21 EMC97177.1 - 4.2e-14 52.3 0.1 9e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMC97177.1 - 0.00012 22.2 0.0 0.00084 19.4 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal Sugar_tr PF00083.19 EMC97178.1 - 4.3e-108 361.7 24.0 5.3e-108 361.4 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC97178.1 - 3e-19 68.9 41.0 1.1e-12 47.3 7.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gcd10p PF04189.8 EMC97179.1 - 2e-79 266.8 0.0 2.5e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family tRNA-synt_1b PF00579.20 EMC97180.1 - 8.2e-76 254.9 0.0 1e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EPL1 PF10513.4 EMC97181.1 - 2.2e-34 119.0 0.2 2.2e-34 119.0 0.1 1.9 2 1 0 2 2 2 1 Enhancer of polycomb-like DUF2508 PF10704.4 EMC97181.1 - 0.052 13.7 1.3 0.2 11.8 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) p450 PF00067.17 EMC97183.1 - 1.3e-44 152.5 0.0 1.6e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EMC97185.1 - 3.9e-110 368.5 26.3 4.8e-110 368.2 18.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC97185.1 - 3.5e-21 75.3 49.7 1.5e-18 66.6 17.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC1 PF03109.11 EMC97186.1 - 2.4e-34 117.8 0.0 1e-33 115.8 0.0 2.1 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.20 EMC97186.1 - 0.076 12.1 0.0 0.29 10.2 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain Glyco_tranf_2_3 PF13641.1 EMC97187.1 - 5e-34 118.0 0.0 8.3e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMC97187.1 - 5.1e-19 68.7 3.7 5.1e-19 68.7 2.6 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMC97187.1 - 2.2e-14 53.4 0.0 3.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMC97187.1 - 6.8e-08 31.9 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EMC97187.1 - 1.8e-06 26.6 4.4 3.1e-06 25.8 1.0 2.2 2 0 0 2 2 2 1 Cellulose synthase CbiQ PF02361.11 EMC97187.1 - 2.7 7.5 9.5 0.21 11.0 2.0 2.4 3 0 0 3 3 3 0 Cobalt transport protein Sugar_tr PF00083.19 EMC97188.1 - 1.3e-106 356.9 23.2 1.6e-106 356.6 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC97188.1 - 1.1e-19 70.3 22.8 1.1e-19 70.3 15.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1304 PF06993.7 EMC97188.1 - 0.046 13.4 11.0 0.46 10.2 1.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) Amidase PF01425.16 EMC97189.1 - 9.8e-101 337.7 0.0 1.2e-100 337.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Mg_trans_NIPA PF05653.9 EMC97190.1 - 4.5e-64 216.2 2.0 8.7e-60 202.2 1.4 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EMC97190.1 - 1.6e-06 28.3 0.5 1.6e-06 28.3 0.4 3.7 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC97190.1 - 0.00011 22.2 0.9 0.00011 22.2 0.6 4.1 3 1 1 4 4 4 1 EamA-like transporter family CD20 PF04103.10 EMC97190.1 - 0.032 14.1 5.2 0.2 11.6 0.0 3.3 3 1 0 3 3 3 0 CD20-like family DUF2976 PF11190.3 EMC97190.1 - 5.7 6.5 8.0 16 5.0 1.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Acyl-CoA_dh_1 PF00441.19 EMC97191.1 - 4.1e-30 104.8 0.1 7.1e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC97191.1 - 2e-15 55.9 0.0 3.9e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMC97191.1 - 1.2e-14 54.8 0.3 3e-14 53.5 0.0 1.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMC97191.1 - 3.3e-13 50.0 0.2 5.3e-13 49.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPA_C PF05181.7 EMC97193.1 - 5.4e-28 96.3 2.7 1.2e-27 95.2 1.9 1.6 1 0 0 1 1 1 1 XPA protein C-terminus zf-AD PF07776.10 EMC97193.1 - 0.037 14.0 1.1 0.077 13.0 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) XPA_N PF01286.13 EMC97193.1 - 0.96 9.1 9.4 0.14 11.8 2.4 2.2 2 0 0 2 2 2 0 XPA protein N-terminal YhfH PF14149.1 EMC97193.1 - 2.8 7.7 11.6 2.2 8.1 1.1 2.5 2 0 0 2 2 2 0 YhfH-like protein DNA_RNApol_7kD PF03604.8 EMC97193.1 - 4 6.9 9.0 9.3 5.8 2.4 2.8 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit 4HBT PF03061.17 EMC97194.1 - 8.7e-07 28.9 0.1 0.028 14.5 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily SPX PF03105.14 EMC97196.1 - 1.1e-17 64.7 1.3 2.5e-10 40.6 0.1 3.0 1 1 1 2 2 2 2 SPX domain Peptidase_M16_C PF05193.16 EMC97196.1 - 0.076 12.6 0.1 0.13 11.9 0.1 1.7 1 1 0 1 1 1 0 Peptidase M16 inactive domain SUZ PF12752.2 EMC97198.1 - 5.5e-14 52.4 1.6 3e-13 50.0 0.2 2.7 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 EMC97198.1 - 6.7e-07 28.9 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain YCII PF03795.9 EMC97199.1 - 0.003 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain AFG1_ATPase PF03969.11 EMC97200.1 - 4.8e-60 203.2 0.6 2.4e-27 95.7 0.1 5.1 4 1 1 5 5 5 5 AFG1-like ATPase AAA_5 PF07728.9 EMC97200.1 - 2.1e-05 24.2 0.0 4.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC97200.1 - 0.00033 20.6 0.4 0.0018 18.2 0.0 2.3 2 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 EMC97200.1 - 0.00046 20.4 0.0 0.00085 19.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC97200.1 - 0.00069 19.7 0.0 0.0022 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EMC97200.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain G-patch PF01585.18 EMC97201.1 - 7.9e-07 28.7 0.3 7.9e-07 28.7 0.2 1.9 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 EMC97201.1 - 3.2e-05 23.6 0.0 7.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC97201.1 - 0.0013 18.2 0.7 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC97201.1 - 0.016 15.1 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AF1Q PF15017.1 EMC97201.1 - 0.034 14.0 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Zn_clus PF00172.13 EMC97203.1 - 1.4e-09 37.6 9.7 2.2e-09 37.0 6.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.15 EMC97204.1 - 7.5e-26 89.8 0.0 9e-26 89.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMC97204.1 - 4.2e-09 36.3 0.1 4.3e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC97204.1 - 1.7e-07 31.3 0.5 1.8e-06 28.0 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EMC97204.1 - 0.00025 20.7 0.2 0.14 11.8 0.0 2.1 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 EMC97204.1 - 0.00076 19.0 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 EMC97204.1 - 0.0011 18.8 0.0 0.0083 16.0 0.0 2.0 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 EMC97204.1 - 0.0024 17.4 0.2 0.29 10.6 0.0 2.1 1 1 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EMC97204.1 - 0.0042 17.0 0.3 0.011 15.7 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 EMC97204.1 - 0.033 13.6 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_5 PF13743.1 EMC97204.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.1 EMC97204.1 - 0.055 12.9 0.1 0.087 12.3 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein DUF796 PF05638.7 EMC97205.1 - 3e-11 43.4 0.0 4.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF796) RRM_1 PF00076.17 EMC97207.1 - 2e-15 56.1 0.0 3.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC97207.1 - 9.5e-14 51.1 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC97207.1 - 1.7e-05 24.5 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EMC97207.1 - 0.0033 15.3 0.3 0.004 15.0 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 EMC97207.1 - 0.084 12.5 1.2 0.12 12.1 0.8 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD STAT_alpha PF01017.15 EMC97207.1 - 0.095 12.4 0.4 0.13 11.9 0.3 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain Imm46 PF15585.1 EMC97207.1 - 0.14 12.2 0.3 0.21 11.6 0.2 1.2 1 0 0 1 1 1 0 Immunity protein 46 ATP-synt_E PF05680.7 EMC97207.1 - 0.17 11.8 1.2 0.25 11.3 0.8 1.2 1 0 0 1 1 1 0 ATP synthase E chain Syntaxin PF00804.20 EMC97207.1 - 0.24 11.5 1.9 0.35 11.0 1.3 1.2 1 0 0 1 1 1 0 Syntaxin DUF4140 PF13600.1 EMC97207.1 - 0.45 10.9 4.4 0.78 10.2 3.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.9 EMC97207.1 - 0.56 9.7 5.7 0.72 9.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.10 EMC97207.1 - 1.1 8.7 4.2 1.8 8.0 2.9 1.3 1 0 0 1 1 1 0 Septum formation initiator Aldo_ket_red PF00248.16 EMC97208.1 - 3e-71 239.5 0.0 3.5e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EMC97209.1 - 3.9e-09 35.6 39.0 3.9e-09 35.6 27.0 3.3 3 1 0 3 3 3 1 Major Facilitator Superfamily Herpes_UL56 PF04534.7 EMC97210.1 - 0.14 11.8 1.2 0.25 11.0 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein Rtt106 PF08512.7 EMC97211.1 - 1.3e-25 89.1 0.0 2.3e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Secretin_N_2 PF07655.8 EMC97212.1 - 0.61 10.4 10.3 1.7 9.0 7.1 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain DNAP_B_exo_N PF08452.5 EMC97213.1 - 0.036 13.3 0.1 0.071 12.3 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal Thaumatin PF00314.12 EMC97215.1 - 0.015 14.7 1.3 0.024 14.0 0.9 1.2 1 0 0 1 1 1 0 Thaumatin family Ufd2P_core PF10408.4 EMC97218.1 - 2.3e-186 620.7 1.1 2.8e-186 620.5 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EMC97218.1 - 9.7e-29 99.1 1.1 2.7e-28 97.7 0.8 1.8 1 0 0 1 1 1 1 U-box domain NPV_P10 PF05531.7 EMC97218.1 - 0.09 13.0 0.1 0.37 11.0 0.1 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 EMC97218.1 - 0.18 12.1 4.7 0.11 12.8 0.3 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal SMN PF06003.7 EMC97220.1 - 0.00052 19.2 9.9 0.0027 16.8 1.0 2.7 1 1 1 3 3 3 2 Survival motor neuron protein (SMN) PAS_9 PF13426.1 EMC97220.1 - 0.047 14.0 0.0 0.059 13.7 0.0 1.2 1 0 0 1 1 1 0 PAS domain SOXp PF12336.3 EMC97220.1 - 0.16 12.5 0.7 0.35 11.5 0.0 1.9 2 0 0 2 2 2 0 SOX transcription factor RRM_1 PF00076.17 EMC97221.1 - 2.1e-12 46.4 0.0 4.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC97221.1 - 1.5e-09 37.7 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC97221.1 - 2.8e-06 27.0 0.0 5.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3120 PF11318.3 EMC97222.1 - 0.035 14.3 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) DUF4094 PF13334.1 EMC97222.1 - 0.065 13.6 0.0 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Ribonuc_red_lgC PF02867.10 EMC97223.1 - 1.6e-215 716.7 0.0 2.2e-215 716.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EMC97223.1 - 3e-24 84.6 0.1 7.2e-24 83.4 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EMC97223.1 - 9.6e-17 61.2 0.0 3.5e-16 59.4 0.0 2.1 1 0 0 1 1 1 1 ATP cone domain CTP_transf_2 PF01467.21 EMC97225.1 - 2.3e-14 53.7 0.1 2.6e-12 47.0 0.0 2.9 3 1 0 3 3 3 2 Cytidylyltransferase CHD5 PF04420.9 EMC97226.1 - 1.4e-53 180.8 0.3 1.6e-53 180.6 0.2 1.0 1 0 0 1 1 1 1 CHD5-like protein DUF2743 PF10899.3 EMC97226.1 - 0.033 13.5 0.4 0.045 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) Microtub_assoc PF07989.6 EMC97226.1 - 0.47 10.3 3.1 2.7 7.9 0.2 2.8 2 1 0 2 2 2 0 Microtubule associated F-box-like PF12937.2 EMC97227.1 - 0.0073 16.0 0.1 0.0073 16.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMC97227.1 - 0.027 14.1 0.8 0.073 12.7 0.0 2.1 2 0 0 2 2 2 0 F-box domain LRR_7 PF13504.1 EMC97227.1 - 0.5 10.7 2.2 5.4 7.6 0.0 3.4 3 0 0 3 3 3 0 Leucine rich repeat DUF647 PF04884.9 EMC97228.1 - 5.2e-94 314.1 0.6 6.9e-94 313.7 0.4 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Flt3_lig PF02947.9 EMC97228.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 flt3 ligand DUF204 PF02659.10 EMC97228.1 - 0.18 11.9 1.3 2.8 8.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF PHO4 PF01384.15 EMC97229.1 - 0.067 11.8 0.0 0.067 11.8 0.0 1.0 1 0 0 1 1 1 0 Phosphate transporter family DUF2414 PF10309.4 EMC97230.1 - 1.9e-18 65.8 0.1 4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF566 PF04484.7 EMC97230.1 - 0.52 9.7 4.8 0.47 9.9 2.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF566) DUF3435 PF11917.3 EMC97231.1 - 1.5e-109 366.5 0.5 1.9e-109 366.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Toxin_3 PF00537.13 EMC97233.1 - 0.097 12.5 0.9 0.14 12.0 0.6 1.2 1 0 0 1 1 1 0 Scorpion toxin-like domain AAA_23 PF13476.1 EMC97234.1 - 0.0062 16.8 7.0 0.011 16.0 4.8 1.5 1 0 0 1 1 1 1 AAA domain Exonuc_VII_L PF02601.10 EMC97234.1 - 0.087 12.0 14.8 0.19 10.9 10.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit OTT_1508_deam PF14441.1 EMC97237.1 - 3.3e-14 52.8 0.0 6.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase dsrm PF00035.20 EMC97238.1 - 5e-05 23.7 0.0 8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif TPD PF14811.1 EMC97240.1 - 1.5e-18 66.6 0.0 3.5e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function TPD sequence-motif YscO PF07321.7 EMC97241.1 - 0.0034 17.2 10.8 0.006 16.4 7.5 1.4 1 0 0 1 1 1 1 Type III secretion protein YscO OEP PF02321.13 EMC97241.1 - 0.016 14.8 6.1 0.026 14.1 4.2 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein DUF3584 PF12128.3 EMC97241.1 - 0.025 11.9 9.8 0.031 11.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LPP PF04728.8 EMC97241.1 - 0.061 13.1 1.8 0.11 12.3 0.4 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FliJ PF02050.11 EMC97241.1 - 0.074 13.1 8.6 0.14 12.2 6.0 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein COG2 PF06148.6 EMC97241.1 - 0.21 11.4 2.6 0.5 10.2 1.8 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NEP PF10167.4 EMC97241.1 - 0.22 11.2 2.3 0.18 11.5 0.5 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF607 PF04678.8 EMC97241.1 - 0.74 9.7 3.9 0.7 9.7 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DivIVA PF05103.8 EMC97241.1 - 0.88 9.6 7.8 0.96 9.5 4.3 1.9 1 1 0 1 1 1 0 DivIVA protein Atg14 PF10186.4 EMC97241.1 - 0.9 8.4 8.2 1.3 7.9 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2203 PF09969.4 EMC97241.1 - 1.2 9.3 5.3 1 9.5 2.4 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Med3 PF11593.3 EMC97241.1 - 2.9 7.0 8.3 0.37 9.9 3.1 1.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal IncA PF04156.9 EMC97241.1 - 3.3 7.2 11.7 4.1 6.9 7.5 1.5 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 EMC97241.1 - 4.4 7.3 9.9 1.9 8.5 2.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DNA_pol_A_exo1 PF01612.15 EMC97242.1 - 5.1e-12 45.6 0.0 1.7e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease KH_3 PF13014.1 EMC97242.1 - 0.012 15.2 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 KH domain OTT_1508_deam PF14441.1 EMC97243.1 - 2.7e-10 40.1 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase CSTF_C PF14304.1 EMC97243.1 - 0.11 11.8 0.6 0.21 10.9 0.4 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Dynamin_N PF00350.18 EMC97245.1 - 5e-27 94.7 0.1 1.2e-26 93.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EMC97245.1 - 2.3e-11 43.0 0.0 4.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Miro PF08477.8 EMC97245.1 - 0.0046 17.4 0.0 0.013 15.9 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EMC97245.1 - 0.053 13.0 0.3 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain GED PF02212.13 EMC97245.1 - 0.054 13.3 1.0 0.38 10.6 0.0 2.8 3 0 0 3 3 3 0 Dynamin GTPase effector domain Ank_2 PF12796.2 EMC97248.1 - 2.2e-26 91.9 0.3 2.1e-10 40.8 0.0 3.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC97248.1 - 4.3e-20 71.6 1.5 5.3e-05 23.6 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EMC97248.1 - 7.3e-20 69.7 4.2 3.3e-05 23.4 0.1 6.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 EMC97248.1 - 5.1e-15 54.0 3.1 0.00076 19.4 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EMC97248.1 - 1.1e-14 54.1 1.2 0.00016 21.8 0.1 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) PBP1_TM PF14812.1 EMC97249.1 - 0.0082 16.4 22.9 0.035 14.4 4.6 2.4 2 0 0 2 2 2 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EMC97249.1 - 0.013 14.9 20.5 0.16 11.4 1.9 2.3 2 0 0 2 2 2 0 Nucleoplasmin Acetyltransf_11 PF13720.1 EMC97249.1 - 0.039 14.1 0.7 0.11 12.6 0.5 1.9 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Spt5_N PF11942.3 EMC97249.1 - 0.051 14.1 29.2 0.18 12.4 8.5 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FAM176 PF14851.1 EMC97249.1 - 0.067 12.8 12.6 0.14 11.8 1.9 2.4 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.6 EMC97249.1 - 0.074 12.8 17.4 0.063 13.0 2.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Peptidase_C37 PF05416.7 EMC97249.1 - 0.15 10.3 3.8 0.21 9.8 2.6 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF1510 PF07423.6 EMC97249.1 - 0.51 9.6 17.3 0.24 10.7 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EMC97249.1 - 0.86 8.8 22.9 1.9 7.6 4.4 2.1 2 0 0 2 2 2 0 SDA1 Pox_RNA_Pol_19 PF05320.7 EMC97249.1 - 0.87 9.3 16.5 3.5 7.3 2.3 2.6 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4611 PF15387.1 EMC97249.1 - 1.3 9.2 19.3 0.1 12.7 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cytomega_UL84 PF06284.6 EMC97249.1 - 1.8 6.9 7.9 2.5 6.4 5.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein VID27 PF08553.5 EMC97249.1 - 2.7 6.0 15.6 0.077 11.2 2.0 2.1 2 0 0 2 2 2 0 VID27 cytoplasmic protein DUF2457 PF10446.4 EMC97249.1 - 2.8 6.5 31.0 1.9 7.1 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) HSP90 PF00183.13 EMC97249.1 - 4.1 5.6 13.5 4.9 5.4 0.7 2.1 2 0 0 2 2 2 0 Hsp90 protein RNase_H2_suC PF08615.6 EMC97249.1 - 4.7 7.0 13.6 1.8 8.4 5.7 2.1 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Sigma70_ner PF04546.8 EMC97249.1 - 7.1 6.1 33.2 0.51 9.9 6.5 2.8 2 1 0 3 3 3 0 Sigma-70, non-essential region MLTD_N PF06474.7 EMC97252.1 - 0.053 13.7 1.3 8.9 6.5 0.2 2.6 2 1 0 2 2 2 0 MltD lipid attachment motif Flo11 PF10182.4 EMC97252.1 - 0.074 12.6 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Flo11 domain AA_permease_2 PF13520.1 EMC97253.1 - 4.1e-35 121.1 39.9 4.9e-35 120.8 27.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC97253.1 - 4.6e-11 41.7 36.1 2.7e-10 39.2 25.0 1.9 1 1 0 1 1 1 1 Amino acid permease DOR PF14839.1 EMC97254.1 - 0.027 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 DOR family zf-C2HC5 PF06221.8 EMC97254.1 - 0.081 12.6 0.8 0.15 11.8 0.6 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Zn_clus PF00172.13 EMC97262.1 - 7.9e-07 28.8 14.2 1.6e-06 27.9 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYTT PF07078.6 EMC97262.1 - 0.098 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Forty-two-three protein APH PF01636.18 EMC97263.1 - 1.1e-09 38.3 0.0 4.5e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC97263.1 - 3e-09 36.7 0.0 6.2e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Mer2 PF09074.5 EMC97266.1 - 0.067 13.1 11.5 0.076 12.9 8.0 1.0 1 0 0 1 1 1 0 Mer2 Prominin PF05478.6 EMC97266.1 - 0.26 8.7 8.5 0.29 8.6 5.9 1.0 1 0 0 1 1 1 0 Prominin DUF4455 PF14643.1 EMC97266.1 - 0.26 9.8 18.1 0.33 9.5 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) LEA_1 PF03760.10 EMC97266.1 - 0.3 11.2 16.8 1.1 9.5 11.5 2.0 1 1 1 2 2 2 0 Late embryogenesis abundant (LEA) group 1 Baculo_PEP_C PF04513.7 EMC97266.1 - 0.44 10.3 5.9 0.54 10.0 4.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YagB_YeeU_YfjZ PF06154.6 EMC97266.1 - 0.46 10.7 3.6 0.53 10.5 2.5 1.1 1 0 0 1 1 1 0 YagB/YeeU/YfjZ family MCM2_N PF12619.3 EMC97266.1 - 1.1 9.1 12.7 1.3 8.9 8.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 DUF4192 PF13830.1 EMC97266.1 - 1.6 8.3 8.3 2 7.9 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) YniB PF14002.1 EMC97266.1 - 2.3 7.6 7.1 3.1 7.2 4.9 1.3 1 0 0 1 1 1 0 YniB-like protein DIT1_PvcA PF05141.7 EMC97266.1 - 2.6 7.2 7.6 2.7 7.2 5.3 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF4268 PF14088.1 EMC97266.1 - 3.3 7.3 10.4 6.7 6.3 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4268) DUF4229 PF14012.1 EMC97266.1 - 3.4 7.6 9.6 6.7 6.6 0.5 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF4229) DUF1795 PF08786.6 EMC97266.1 - 3.6 7.4 13.5 0.98 9.2 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1795) Tox-PL PF15644.1 EMC97266.1 - 3.7 8.3 6.6 12 6.7 4.6 1.7 1 1 0 1 1 1 0 Papain fold toxin 1 ApoO PF09769.4 EMC97266.1 - 3.8 7.2 6.3 4.2 7.0 4.3 1.1 1 0 0 1 1 1 0 Apolipoprotein O TnpV PF14198.1 EMC97266.1 - 3.9 7.3 15.8 5.1 7.0 10.9 1.2 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Phe_tRNA-synt_N PF02912.13 EMC97266.1 - 4.4 7.1 12.4 1.6 8.5 1.3 1.8 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain MRP-L46 PF11788.3 EMC97266.1 - 4.8 7.8 10.2 5.9 7.5 7.1 1.1 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Fzo_mitofusin PF04799.8 EMC97266.1 - 5.3 6.4 12.6 5.4 6.3 8.7 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF883 PF05957.8 EMC97266.1 - 5.7 7.4 12.6 9 6.7 8.7 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YjcZ PF13990.1 EMC97266.1 - 6.3 5.8 15.2 6.9 5.7 10.5 1.0 1 0 0 1 1 1 0 YjcZ-like protein Hexokinase_1 PF00349.16 EMC97266.1 - 6.4 6.0 7.4 7.5 5.8 5.1 1.2 1 0 0 1 1 1 0 Hexokinase AAA-ATPase_like PF09820.4 EMC97266.1 - 6.7 5.7 7.1 7.1 5.6 4.9 1.0 1 0 0 1 1 1 0 Predicted AAA-ATPase YlqD PF11068.3 EMC97266.1 - 6.8 6.7 26.6 8.2 6.4 18.4 1.2 1 0 0 1 1 1 0 YlqD protein His_Phos_2 PF00328.17 EMC97266.1 - 6.8 5.9 9.3 7.2 5.8 6.4 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF2458 PF10454.4 EMC97266.1 - 6.9 6.5 19.4 7.1 6.5 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) cwf21 PF08312.7 EMC97266.1 - 7.4 6.5 17.8 2.4 8.0 6.4 2.2 1 1 1 2 2 2 0 cwf21 domain DUF4047 PF13256.1 EMC97266.1 - 7.9 6.4 13.1 11 6.0 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) EST1_DNA_bind PF10373.4 EMC97267.1 - 0.00018 20.8 0.3 0.0014 17.9 0.1 2.2 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain YMF19 PF02326.10 EMC97273.1 - 0.94 10.0 4.1 14 6.3 0.6 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 TPR_16 PF13432.1 EMC97276.1 - 0.042 14.5 0.1 0.95 10.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.11 EMC97277.1 - 0.026 14.3 0.0 0.26 11.1 0.0 2.2 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EMC97278.1 - 1.4e-37 128.9 0.0 1.5e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMC97278.1 - 0.0013 18.4 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_2 PF12796.2 EMC97279.1 - 5.1e-07 29.9 0.0 5.4e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC97279.1 - 8.5e-07 28.4 0.0 0.033 14.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMC97279.1 - 0.00022 21.6 0.0 0.00027 21.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC97279.1 - 0.042 14.0 0.0 10 6.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Pectate_lyase_2 PF06917.7 EMC97281.1 - 0.0034 15.6 0.1 0.0037 15.5 0.1 1.0 1 0 0 1 1 1 1 Periplasmic pectate lyase E1-E2_ATPase PF00122.15 EMC97282.1 - 2.6e-42 144.4 7.7 2.6e-42 144.4 5.3 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EMC97282.1 - 2.1e-26 93.6 0.1 3.8e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC97282.1 - 2.2e-09 37.7 0.0 4.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMC97282.1 - 1.3e-08 34.8 0.1 3.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EMC97282.1 - 8.1e-05 22.3 0.0 0.00042 19.9 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pectate_lyase_2 PF06917.7 EMC97282.1 - 0.18 10.0 0.0 0.24 9.6 0.0 1.1 1 0 0 1 1 1 0 Periplasmic pectate lyase Hydrolase PF00702.21 EMC97283.1 - 1.6e-16 61.3 0.0 2.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC97283.1 - 6.1e-06 26.0 0.0 8.6e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC97283.1 - 7.3e-05 23.0 0.0 0.00017 21.8 0.0 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Pectate_lyase_2 PF06917.7 EMC97283.1 - 0.025 12.8 0.0 0.032 12.4 0.0 1.1 1 0 0 1 1 1 0 Periplasmic pectate lyase DUF4509 PF14970.1 EMC97285.1 - 0.031 13.9 2.4 0.034 13.8 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) DUF1593 PF07632.6 EMC97285.1 - 0.038 13.2 0.1 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) F-box-like PF12937.2 EMC97288.1 - 7.8e-05 22.3 0.1 7.8e-05 22.3 0.1 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EMC97288.1 - 0.0011 18.5 0.1 0.0011 18.5 0.1 1.9 2 0 0 2 2 2 1 F-box domain SUR7 PF06687.7 EMC97290.1 - 2.1e-13 50.3 6.8 2.5e-13 50.0 4.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.6 EMC97290.1 - 0.043 13.4 7.0 0.061 12.9 0.1 2.5 2 0 0 2 2 2 0 Amastin surface glycoprotein Racemase_4 PF13615.1 EMC97290.1 - 0.12 12.5 0.4 7.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Putative alanine racemase DnaJ PF00226.26 EMC97291.1 - 1.2e-10 40.9 3.1 1.2e-10 40.9 2.2 2.4 2 0 0 2 2 2 1 DnaJ domain FAD_binding_8 PF08022.7 EMC97298.1 - 1e-05 25.3 0.0 0.0066 16.3 0.0 2.4 1 1 1 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 EMC97298.1 - 0.074 12.9 0.1 0.33 10.8 0.0 2.0 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMC97298.1 - 0.2 11.7 24.2 0.039 14.0 10.4 3.4 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF3723 PF12520.3 EMC97300.1 - 3.6e-87 292.9 5.8 5.6e-80 269.2 0.9 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Patatin PF01734.17 EMC97301.1 - 6.6e-12 45.7 0.4 3.8e-07 30.2 0.0 3.3 3 0 0 3 3 3 2 Patatin-like phospholipase TPD52 PF04201.10 EMC97303.1 - 0.0013 18.4 0.1 0.0019 17.9 0.1 1.2 1 0 0 1 1 1 1 Tumour protein D52 family THOC7 PF05615.8 EMC97303.1 - 0.018 15.2 4.6 0.027 14.7 2.5 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 ATG16 PF08614.6 EMC97303.1 - 0.071 12.9 11.0 0.23 11.2 5.5 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 EMC97303.1 - 0.13 9.5 14.2 0.17 9.2 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NYD-SP28 PF14772.1 EMC97303.1 - 0.14 12.2 7.8 0.062 13.3 2.0 2.3 1 1 1 2 2 2 0 Sperm tail COG2 PF06148.6 EMC97303.1 - 0.14 12.0 1.5 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EMC97303.1 - 3.6 7.1 15.8 6.6 6.2 5.6 2.5 1 1 1 2 2 2 0 IncA protein Phage_GPO PF05929.6 EMC97304.1 - 0.043 13.0 2.4 0.076 12.2 0.9 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase EcoR124_C PF12008.3 EMC97304.1 - 0.046 12.9 0.8 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF2852 PF11014.3 EMC97304.1 - 1 9.3 4.0 0.3 11.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF3774 PF12609.3 EMC97306.1 - 0.069 14.0 0.1 0.17 12.7 0.0 1.6 2 0 0 2 2 2 0 Wound-induced protein zf-RING_2 PF13639.1 EMC97308.1 - 1.4e-09 37.6 5.2 1.4e-09 37.6 3.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EMC97308.1 - 4.5e-05 23.1 3.1 4.5e-05 23.1 2.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EMC97308.1 - 0.00011 22.1 5.9 0.00011 22.1 4.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC97308.1 - 0.00012 21.7 5.3 0.00012 21.7 3.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC97308.1 - 0.0002 21.4 4.0 0.00057 19.9 2.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EMC97308.1 - 0.00065 19.2 7.3 0.0018 17.8 5.1 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EMC97308.1 - 0.0008 19.0 2.7 0.0008 19.0 1.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.12 EMC97308.1 - 0.0014 18.0 1.5 0.0037 16.6 1.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.1 EMC97308.1 - 0.0097 15.6 5.6 0.037 13.7 4.0 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EMC97308.1 - 0.014 15.4 3.2 0.066 13.2 1.9 2.4 2 0 0 2 2 2 0 RING-like domain zf-C3HC4 PF00097.20 EMC97308.1 - 0.014 15.0 5.3 0.014 15.0 3.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EMC97308.1 - 0.035 14.1 6.7 0.086 12.8 4.6 1.7 1 0 0 1 1 1 0 RING-variant domain Baculo_IE-1 PF05290.6 EMC97308.1 - 0.61 9.8 6.2 0.21 11.3 1.2 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) FANCL_C PF11793.3 EMC97308.1 - 1.1 9.2 14.0 0.42 10.5 6.6 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain Ecm33 PF12454.3 EMC97309.1 - 9.5e-13 47.7 4.2 9.5e-13 47.7 2.9 2.1 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EMC97309.1 - 4.4e-06 26.6 2.4 0.071 13.0 0.0 4.0 1 1 4 5 5 5 2 Receptor L domain RPN7 PF10602.4 EMC97309.1 - 0.15 11.4 0.0 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Anp1 PF03452.9 EMC97312.1 - 2.4e-107 358.1 0.0 2.9e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Remorin_N PF03766.8 EMC97312.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Remorin, N-terminal region Pep3_Vps18 PF05131.9 EMC97314.1 - 3.5e-44 149.7 0.0 4.4e-43 146.2 0.0 2.4 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EMC97314.1 - 1.9e-08 33.9 7.1 2.6e-07 30.3 1.3 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_5 PF14634.1 EMC97314.1 - 0.0016 18.1 3.0 0.0038 16.9 0.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC97314.1 - 0.0039 16.9 0.6 0.0039 16.9 0.4 2.0 2 0 0 2 2 2 1 Ring finger domain PPR_3 PF13812.1 EMC97314.1 - 0.0056 16.8 1.1 2.3 8.7 0.0 3.8 4 0 0 4 4 4 1 Pentatricopeptide repeat domain RGCC PF15151.1 EMC97314.1 - 0.014 15.8 0.2 8.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Response gene to complement 32 protein family Apc3 PF12895.2 EMC97314.1 - 0.039 14.0 2.4 0.12 12.4 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMC97314.1 - 0.043 14.1 0.1 0.043 14.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps39_2 PF10367.4 EMC97314.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 EMC97314.1 - 1.3 8.7 4.6 0.65 9.7 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 EMC97315.1 - 4.1e-62 209.6 0.0 9e-62 208.5 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC97315.1 - 8.6e-13 47.9 0.0 2.2e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EMC97315.1 - 3.6e-08 32.9 6.3 3.6e-08 32.9 4.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EMC97315.1 - 2.4e-06 27.1 0.0 5.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 EMC97315.1 - 4.2e-05 23.4 6.0 4.2e-05 23.4 4.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 EMC97315.1 - 0.00027 19.8 0.2 0.0012 17.7 0.0 2.0 3 0 0 3 3 3 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.1 EMC97315.1 - 0.00051 19.8 6.5 0.00051 19.8 4.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC97315.1 - 0.0011 18.6 5.9 0.0011 18.6 4.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC97315.1 - 0.0016 18.1 7.2 0.0016 18.1 5.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC97315.1 - 0.0019 18.0 6.0 0.0019 18.0 4.1 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EMC97315.1 - 0.028 14.2 2.1 0.09 12.5 1.5 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 EMC97315.1 - 0.035 13.6 10.9 0.41 10.1 2.2 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_UBOX PF13445.1 EMC97315.1 - 0.14 11.8 5.8 0.14 11.9 2.3 2.4 2 0 0 2 2 2 0 RING-type zinc-finger DUF4316 PF14195.1 EMC97315.1 - 0.52 10.4 3.1 1 9.4 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4316) Zn-ribbon_8 PF09723.5 EMC97315.1 - 9.6 6.2 13.3 8.4 6.4 1.7 2.8 2 0 0 2 2 2 0 Zinc ribbon domain Med18 PF09637.5 EMC97316.1 - 4.1e-34 118.2 0.0 1.2e-32 113.4 0.0 2.0 1 1 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EMC97317.1 - 2.1e-38 131.7 0.5 2.4e-38 131.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF202 PF02656.10 EMC97318.1 - 2.2e-12 47.0 5.2 2.2e-12 47.0 3.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF981 PF06168.6 EMC97318.1 - 0.024 14.4 1.1 0.03 14.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF4131 PF13567.1 EMC97318.1 - 2.2 7.6 7.7 1.6 8.0 3.7 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Tctex-1 PF03645.8 EMC97319.1 - 5.4e-34 116.1 0.0 6.1e-34 115.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M24 PF00557.19 EMC97320.1 - 1.4e-44 152.1 0.3 2.2e-44 151.5 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.14 EMC97320.1 - 0.015 13.9 0.0 0.023 13.2 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase Ytp1 PF10355.4 EMC97321.1 - 2.3e-85 286.0 12.6 2.3e-85 286.0 8.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EMC97321.1 - 6e-32 109.3 2.2 6e-32 109.3 1.5 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) zf-DHHC PF01529.15 EMC97321.1 - 0.44 9.9 4.2 0.29 10.5 0.2 2.3 2 1 0 2 2 2 0 DHHC palmitoyltransferase Saccharop_dh PF03435.13 EMC97322.1 - 1.2e-120 403.0 0.0 1.6e-120 402.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMC97322.1 - 2.6e-06 27.5 0.1 4.8e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EMC97322.1 - 0.011 15.1 0.2 0.027 13.8 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EMC97322.1 - 0.022 15.0 0.2 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DER1 PF04511.10 EMC97323.1 - 1.8e-30 105.9 2.2 2.1e-30 105.6 1.5 1.0 1 0 0 1 1 1 1 Der1-like family NAD_kinase PF01513.16 EMC97324.1 - 1e-38 132.7 0.0 6.8e-38 130.0 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 EMC97325.1 - 2.3e-25 88.5 0.0 3.8e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ApbA_C PF08546.6 EMC97327.1 - 4.7e-29 100.9 0.0 7.1e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMC97327.1 - 3e-21 75.4 0.1 4.3e-20 71.7 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF1649 PF07855.7 EMC97328.1 - 3.8e-46 156.7 0.0 4.4e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) HATPase_c PF02518.21 EMC97329.1 - 7.8e-23 80.3 0.1 1.9e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMC97329.1 - 1.2e-16 60.7 0.1 2.1e-15 56.6 0.0 2.9 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMC97329.1 - 1.5e-14 53.6 0.0 8.8e-14 51.2 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EMC97329.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.1 EMC97329.1 - 0.022 14.8 0.2 0.99 9.5 0.0 3.3 3 1 0 3 3 3 0 GAF domain PRCC PF10253.4 EMC97329.1 - 1.5 9.5 8.4 0.048 14.3 1.2 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Bravo_FIGEY PF13882.1 EMC97330.1 - 0.012 16.5 0.9 0.012 16.5 0.7 1.9 2 0 0 2 2 2 0 Bravo-like intracellular region Pox_Ag35 PF03286.9 EMC97330.1 - 0.043 13.3 4.5 0.054 13.0 3.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ORC6 PF05460.8 EMC97330.1 - 0.1 11.6 3.2 0.12 11.4 2.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DTHCT PF08070.6 EMC97330.1 - 0.28 11.8 8.7 0.48 11.1 5.9 1.5 1 1 0 1 1 1 0 DTHCT (NUC029) region HALZ PF02183.13 EMC97331.1 - 0.00058 19.5 0.2 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper EzrA PF06160.7 EMC97331.1 - 0.14 10.3 0.0 0.17 10.0 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Med3 PF11593.3 EMC97331.1 - 1 8.5 6.3 1.2 8.2 4.4 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Semialdhyde_dh PF01118.19 EMC97332.1 - 0.0018 18.5 0.0 0.0028 17.9 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EMC97332.1 - 0.0025 17.2 0.0 0.0047 16.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC97332.1 - 0.0041 17.1 0.0 0.0065 16.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMC97332.1 - 0.0091 14.9 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EMC97332.1 - 0.014 14.6 0.0 0.046 12.9 0.0 1.7 1 1 0 1 1 1 0 NmrA-like family DapB_N PF01113.15 EMC97332.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EMC97332.1 - 0.063 12.2 0.0 0.096 11.5 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein Saccharop_dh PF03435.13 EMC97332.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase PAN_4 PF14295.1 EMC97333.1 - 7.3e-28 96.0 21.0 1.4e-08 34.3 0.8 4.9 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.6 EMC97333.1 - 6.2e-06 25.9 15.3 0.32 10.8 0.4 5.0 4 0 0 4 4 4 4 PAN-like domain Nop14 PF04147.7 EMC97333.1 - 0.27 9.1 7.7 0.48 8.2 5.3 1.3 1 0 0 1 1 1 0 Nop14-like family PAN_3 PF08277.7 EMC97333.1 - 4.9 6.8 16.7 0.94 9.1 0.2 4.7 4 0 0 4 4 4 0 PAN-like domain Pept_tRNA_hydro PF01195.14 EMC97334.1 - 2.7e-41 141.1 0.0 3e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase MOSC_N PF03476.11 EMC97335.1 - 6.9e-16 58.0 0.0 1.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EMC97335.1 - 8.3e-10 38.2 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Cuticle_1 PF08140.6 EMC97335.1 - 0.025 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Zn_clus PF00172.13 EMC97336.1 - 2.5e-10 40.1 12.7 4.6e-10 39.2 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMC97336.1 - 3.5e-08 32.4 0.3 0.00029 19.5 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-B_box PF00643.19 EMC97339.1 - 0.0026 17.6 3.9 0.0046 16.8 2.7 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-HIT PF04438.11 EMC97339.1 - 0.0031 17.1 5.4 0.0031 17.1 3.7 1.6 2 0 0 2 2 2 1 HIT zinc finger Desulfoferrod_N PF06397.7 EMC97339.1 - 0.055 12.8 2.1 5.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain FeS PF04060.8 EMC97339.1 - 0.31 10.6 6.2 0.15 11.6 2.6 1.7 2 0 0 2 2 2 0 Putative Fe-S cluster DBD_Tnp_Mut PF03108.10 EMC97339.1 - 0.34 10.5 5.0 0.46 10.1 3.5 1.2 1 0 0 1 1 1 0 MuDR family transposase Ogr_Delta PF04606.7 EMC97339.1 - 0.88 9.2 0.1 0.88 9.2 0.1 2.7 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger C1_3 PF07649.7 EMC97339.1 - 1.3 9.1 5.4 2.5 8.1 3.7 1.5 1 0 0 1 1 1 0 C1-like domain zf-CCHC_3 PF13917.1 EMC97339.1 - 1.4 8.7 9.4 1.2 8.9 2.3 2.3 1 1 1 2 2 2 0 Zinc knuckle C1_2 PF03107.11 EMC97339.1 - 2.8 8.1 8.0 5.5 7.1 5.6 1.5 1 1 0 1 1 1 0 C1 domain Zn-ribbon_8 PF09723.5 EMC97339.1 - 2.9 7.9 10.5 16 5.5 0.1 2.7 2 1 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.7 EMC97339.1 - 2.9 7.9 9.3 2.1e+02 1.9 6.4 2.2 1 1 0 1 1 1 0 TFIIH C1-like domain DUF2296 PF10058.4 EMC97339.1 - 5.4 6.8 10.1 0.63 9.8 0.5 2.3 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) ZZ PF00569.12 EMC97339.1 - 8.3 6.0 10.0 21 4.7 0.4 2.6 1 1 1 2 2 2 0 Zinc finger, ZZ type Pkinase PF00069.20 EMC97341.1 - 4.3e-61 206.3 0.0 6e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97341.1 - 4.6e-27 94.7 0.0 6.5e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC97341.1 - 0.0088 15.0 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SSB PF00436.20 EMC97343.1 - 5e-16 58.4 0.0 6.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4395 PF14340.1 EMC97344.1 - 0.085 12.9 0.1 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) HSF_DNA-bind PF00447.12 EMC97345.1 - 3.7e-27 94.5 0.1 1.2e-26 92.9 0.0 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 EMC97345.1 - 0.034 13.9 2.5 0.57 10.0 0.1 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EMC97345.1 - 0.047 13.4 5.5 0.055 13.1 0.2 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 EMC97345.1 - 0.21 11.6 4.9 0.35 10.9 0.1 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ABC2_membrane_3 PF12698.2 EMC97345.1 - 0.57 9.1 1.9 1.1 8.1 1.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein IncA PF04156.9 EMC97345.1 - 6 6.4 6.8 5.1 6.6 1.0 2.6 2 0 0 2 2 2 0 IncA protein ORC6 PF05460.8 EMC97346.1 - 3.9e-28 98.5 2.7 6.1e-23 81.5 5.0 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) RPEL PF02755.10 EMC97346.1 - 0.085 12.2 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 RPEL repeat MFS_1 PF07690.11 EMC97348.1 - 6.7e-40 136.8 28.6 3.6e-38 131.1 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC97348.1 - 3.9e-09 35.6 6.3 7.1e-09 34.7 1.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EMC97348.1 - 0.00019 19.7 3.0 0.00028 19.2 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EMC97348.1 - 0.00061 18.2 19.1 0.00085 17.8 4.6 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.14 EMC97348.1 - 0.026 13.1 7.6 0.086 11.3 2.2 2.3 1 1 1 2 2 2 0 LacY proton/sugar symporter Thioredoxin PF00085.15 EMC97349.1 - 0.00034 20.2 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin UAA PF08449.6 EMC97350.1 - 3.5e-11 42.5 20.5 4.3e-11 42.2 14.2 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMC97350.1 - 7.5e-10 38.6 8.0 7.5e-10 38.6 5.5 2.8 2 2 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EMC97350.1 - 0.014 15.4 8.1 0.014 15.4 5.6 2.2 2 0 0 2 2 2 0 EamA-like transporter family UPF0370 PF13980.1 EMC97350.1 - 0.16 11.8 0.1 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Peptidase_A24 PF01478.13 EMC97350.1 - 0.17 12.0 0.3 0.17 12.0 0.2 3.8 3 2 1 4 4 4 0 Type IV leader peptidase family Multi_Drug_Res PF00893.14 EMC97350.1 - 0.17 12.3 14.6 0.43 11.0 1.1 2.9 2 1 0 2 2 2 0 Small Multidrug Resistance protein Plasmod_MYXSPDY PF07981.6 EMC97351.1 - 0.066 12.9 0.7 0.11 12.1 0.5 1.4 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Cu-oxidase_3 PF07732.10 EMC97352.1 - 1.9e-41 140.4 0.4 1.9e-41 140.4 0.3 2.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC97352.1 - 3.4e-32 110.8 7.8 1.3e-28 99.2 1.4 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EMC97352.1 - 3.6e-32 111.4 0.7 1.4e-28 99.8 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase zf-H2C2_2 PF13465.1 EMC97356.1 - 1.9e-22 78.3 24.8 1e-09 38.1 0.3 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC97356.1 - 1.6e-21 75.2 19.4 3.9e-05 23.7 0.8 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC97356.1 - 1.5e-13 49.9 16.8 0.00055 20.0 0.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EMC97356.1 - 7.2e-05 22.8 6.0 0.43 10.8 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC97356.1 - 0.062 13.2 0.4 0.062 13.2 0.3 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC97356.1 - 0.088 12.5 0.7 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EMC97356.1 - 0.29 11.0 10.2 7.2 6.6 0.1 4.2 4 0 0 4 4 4 0 Zinc ribbon domain Ogr_Delta PF04606.7 EMC97356.1 - 1 9.0 5.8 25 4.6 0.2 3.5 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.3 EMC97356.1 - 1.1 9.5 6.2 7.7 6.7 0.1 3.4 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 EMC97356.1 - 1.4 8.7 9.3 2.8 7.8 1.7 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain CHORD PF04968.7 EMC97356.1 - 9.7 6.5 13.8 21 5.4 0.4 3.9 1 1 3 4 4 4 0 CHORD Antimicrobial14 PF08109.6 EMC97357.1 - 0.12 12.2 0.4 0.31 10.8 0.1 1.7 2 0 0 2 2 2 0 Lactocin 705 family WD40 PF00400.27 EMC97358.1 - 5e-72 235.4 16.9 1.9e-11 43.3 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EMC97358.1 - 1.5e-10 41.0 1.2 1.5e-10 41.0 0.9 2.0 2 0 0 2 2 2 1 Tup N-terminal Cytochrom_D1 PF02239.11 EMC97358.1 - 1.9e-05 23.1 0.3 0.00029 19.2 0.1 2.4 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EMC97358.1 - 8e-05 21.5 0.1 0.05 12.3 0.0 3.1 1 1 2 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EMC97358.1 - 0.00012 20.4 0.6 0.29 9.2 0.0 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EMC97358.1 - 0.011 14.8 0.1 2.9 6.9 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal MMS1_N PF10433.4 EMC97358.1 - 0.056 11.5 0.0 7.8 4.5 0.0 2.3 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Erf4 PF10256.4 EMC97359.1 - 2.5e-27 95.0 0.0 2.9e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Peptidase_M24 PF00557.19 EMC97360.1 - 4.7e-45 153.7 0.0 7.1e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMC97360.1 - 6.3e-24 84.9 0.1 1.6e-19 70.7 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ArgJ PF01960.13 EMC97361.1 - 4.1e-134 446.8 1.0 6.3e-134 446.2 0.7 1.3 1 0 0 1 1 1 1 ArgJ family UBA PF00627.26 EMC97362.1 - 0.001 18.8 0.2 0.0035 17.1 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EMC97362.1 - 0.0016 17.9 0.7 0.0035 16.8 0.1 1.9 2 0 0 2 2 2 1 UBA-like domain UQ_con PF00179.21 EMC97363.1 - 4.4e-39 133.1 0.0 5.5e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMC97363.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain Paxillin PF03535.8 EMC97363.1 - 0.11 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Paxillin family Spo12 PF05032.7 EMC97364.1 - 6.2e-08 32.1 0.1 1.3e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Spo12 family DKCLD PF08068.7 EMC97365.1 - 6e-29 99.7 0.0 4.2e-28 97.0 0.0 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EMC97365.1 - 4.1e-24 85.4 0.1 2.7e-21 76.2 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EMC97365.1 - 7.5e-20 70.4 1.6 1.5e-19 69.5 1.1 1.5 1 0 0 1 1 1 1 PUA domain Ldh_1_N PF00056.18 EMC97366.1 - 2.2e-18 66.4 0.0 2.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMC97366.1 - 0.001 17.8 0.0 0.0012 17.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family YcfA PF07927.7 EMC97366.1 - 0.021 14.7 2.4 0.035 14.0 1.7 1.4 1 0 0 1 1 1 0 YcfA-like protein THF_DHG_CYH_C PF02882.14 EMC97366.1 - 0.021 13.8 0.1 0.27 10.3 0.1 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.11 EMC97367.1 - 6.4e-33 113.9 30.3 6.4e-33 113.9 21.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 EMC97367.1 - 0.35 10.8 3.3 0.53 10.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) AAA PF00004.24 EMC97368.1 - 1.1e-18 67.7 0.0 2.6e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC97368.1 - 3.2e-05 23.9 0.0 0.0002 21.3 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMC97368.1 - 0.00099 19.2 0.1 0.031 14.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EMC97368.1 - 0.0025 17.3 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EMC97368.1 - 0.021 14.9 0.0 0.077 13.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Torsin PF06309.6 EMC97368.1 - 0.049 13.5 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Torsin NACHT PF05729.7 EMC97368.1 - 0.13 11.9 0.0 0.31 10.6 0.0 1.7 1 1 0 1 1 1 0 NACHT domain NMT1 PF09084.6 EMC97369.1 - 8.9e-36 123.4 0.0 1.1e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EMC97369.1 - 0.0035 16.7 0.0 0.054 12.8 0.0 2.1 1 1 1 2 2 2 1 NMT1-like family HABP4_PAI-RBP1 PF04774.10 EMC97370.1 - 0.027 14.9 6.5 0.075 13.5 4.5 1.8 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Thiolase_C PF02803.13 EMC97373.1 - 7.7e-13 47.9 5.0 2.2e-12 46.5 0.8 3.2 2 1 2 4 4 4 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EMC97373.1 - 7.1e-07 28.8 0.8 4.9e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EMC97373.1 - 3.5e-05 22.9 0.2 0.00017 20.6 0.0 2.3 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EMC97373.1 - 0.0002 20.9 0.2 0.00045 19.7 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMC97373.1 - 0.0031 17.3 1.3 0.34 10.7 0.0 3.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 EMC97373.1 - 0.0078 14.6 0.4 0.02 13.3 0.1 1.7 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) HMA PF00403.21 EMC97374.1 - 2.7e-17 62.6 2.1 3.2e-17 62.4 1.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain phiKZ_IP PF12699.2 EMC97374.1 - 0.034 13.0 0.1 0.04 12.8 0.1 1.0 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins DUF1677 PF07911.8 EMC97374.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) BRO1 PF03097.13 EMC97375.1 - 1.2e-113 379.6 2.1 1.2e-113 379.6 1.5 2.3 2 0 0 2 2 2 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMC97375.1 - 3.7e-75 252.6 7.3 3.7e-75 252.6 5.0 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV PilX_N PF14341.1 EMC97376.1 - 0.12 12.0 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 PilX N-terminal Fungal_trans PF04082.13 EMC97377.1 - 1.4e-28 99.4 0.0 2.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC97377.1 - 3.3e-08 33.3 8.8 7.3e-08 32.1 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 EMC97377.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pyr_redox_2 PF07992.9 EMC97378.1 - 3.9e-37 128.1 0.2 5.9e-37 127.5 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMC97378.1 - 6.9e-36 122.6 1.3 2.4e-34 117.6 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EMC97378.1 - 8.6e-18 64.5 0.8 2.3e-16 59.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC97378.1 - 3.7e-10 40.2 0.0 6.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC97378.1 - 0.00022 20.2 0.0 0.00039 19.4 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EMC97378.1 - 0.00052 19.6 0.3 0.15 11.6 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EMC97378.1 - 0.0022 16.9 1.3 0.0022 16.9 0.9 2.1 1 1 1 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EMC97378.1 - 0.003 17.2 0.4 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EMC97378.1 - 0.0038 16.3 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EMC97378.1 - 0.0088 15.2 0.2 0.62 9.1 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EMC97378.1 - 0.012 14.5 0.7 0.13 11.1 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EMC97378.1 - 0.024 13.5 1.7 0.18 10.6 0.6 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EMC97378.1 - 0.13 10.7 2.8 0.35 9.3 0.4 2.3 2 1 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 EMC97378.1 - 0.22 11.5 3.4 0.38 10.8 1.6 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Ribosom_S12_S23 PF00164.20 EMC97379.1 - 1.1e-40 137.8 0.4 1.3e-40 137.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PIG-P PF08510.7 EMC97380.1 - 2.9e-45 152.9 0.2 3.6e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 PIG-P DUF4131 PF13567.1 EMC97380.1 - 0.035 13.5 0.3 0.059 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DPM2 PF07297.7 EMC97380.1 - 1.5 9.1 8.5 2.5 8.4 5.9 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PH PF00169.24 EMC97381.1 - 0.053 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 PH domain MFS_2 PF13347.1 EMC97382.1 - 2.8e-07 29.2 23.7 1.6e-06 26.7 16.5 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 EMC97382.1 - 0.45 10.3 5.4 5.8 6.7 0.0 3.6 3 0 0 3 3 3 0 MFS_1 like family G6PD_C PF02781.11 EMC97383.1 - 3.5e-134 446.2 0.0 5.6e-134 445.5 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EMC97383.1 - 3.9e-66 222.7 0.0 7.5e-66 221.8 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CZB PF13682.1 EMC97383.1 - 0.0047 17.0 0.5 0.01 15.9 0.3 1.6 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain DUF4455 PF14643.1 EMC97383.1 - 0.071 11.7 1.4 0.1 11.1 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Ribosomal_L35Ae PF01247.13 EMC97384.1 - 9.5e-41 137.4 0.7 1.1e-40 137.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EMC97384.1 - 0.003 17.4 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Brix PF04427.13 EMC97385.1 - 1.6e-37 129.0 0.0 2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.18 EMC97386.1 - 1.4e-71 240.7 2.6 1.4e-71 240.7 1.8 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EMC97386.1 - 1e-47 161.6 16.8 1e-47 161.6 11.6 4.8 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 EMC97386.1 - 3.1e-16 58.9 0.0 7.1e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDP-OH_P_transf PF01066.16 EMC97387.1 - 1.3e-15 57.5 11.0 2.9e-15 56.4 7.6 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF1304 PF06993.7 EMC97387.1 - 0.12 12.0 0.2 0.12 12.0 0.1 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1304) Gti1_Pac2 PF09729.4 EMC97388.1 - 1.1e-60 204.3 0.0 1.3e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family MIF4G_like PF09088.6 EMC97391.1 - 1.2e-77 259.6 0.5 1.9e-77 259.0 0.4 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EMC97391.1 - 2.2e-47 161.4 0.0 3.3e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EMC97391.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain G10 PF01125.12 EMC97392.1 - 3.7e-65 217.8 5.0 4.1e-65 217.7 3.5 1.0 1 0 0 1 1 1 1 G10 protein SNF2_N PF00176.18 EMC97393.1 - 8.1e-86 287.4 1.2 8.1e-86 287.4 0.9 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EMC97393.1 - 3.9e-23 81.1 1.2 1.1e-22 79.7 0.1 2.4 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.1 EMC97393.1 - 1e-17 64.0 1.6 6.7e-17 61.4 1.1 2.5 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 EMC97393.1 - 3.6e-16 58.7 0.0 3.6e-16 58.7 0.0 3.7 5 0 0 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.8 EMC97393.1 - 3.6e-13 49.0 12.7 3.6e-13 49.0 8.8 2.6 2 0 0 2 2 2 1 HSA QLQ PF08880.6 EMC97393.1 - 3.3e-07 29.6 1.9 3.3e-07 29.6 1.3 2.8 2 0 0 2 2 2 1 QLQ IGPD PF00475.13 EMC97394.1 - 2.2e-60 202.7 0.5 3e-60 202.2 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Complex1_LYR_2 PF13233.1 EMC97395.1 - 0.004 17.5 0.2 0.0046 17.4 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMC97395.1 - 0.0041 16.8 0.3 0.0066 16.2 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) R-HINP1I PF11463.3 EMC97395.1 - 0.0088 15.4 0.1 0.0094 15.3 0.1 1.1 1 0 0 1 1 1 1 R.HinP1I restriction endonuclease Complex1_LYR_1 PF13232.1 EMC97395.1 - 0.036 14.2 0.5 0.048 13.8 0.3 1.4 1 1 0 1 1 1 0 Complex1_LYR-like DUF1140 PF06600.6 EMC97395.1 - 0.3 11.2 1.7 0.36 10.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) Pkinase PF00069.20 EMC97396.1 - 1e-63 214.9 0.0 1.2e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97396.1 - 2.7e-24 85.6 0.0 3.5e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC97396.1 - 4.2e-07 29.2 0.0 2.7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC97396.1 - 0.0026 17.5 0.2 0.025 14.2 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family GIDA PF01134.17 EMC97398.1 - 4.8e-157 522.8 0.0 5.8e-157 522.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EMC97398.1 - 3.1e-17 62.3 0.0 7.5e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EMC97398.1 - 4.7e-07 29.8 0.4 1.4e-06 28.3 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC97398.1 - 2.1e-06 27.0 0.5 3.4e-06 26.3 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EMC97398.1 - 0.00035 19.6 1.5 0.17 10.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC97398.1 - 0.00041 19.3 2.0 0.00051 19.0 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EMC97398.1 - 0.013 15.8 0.1 0.038 14.3 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMC97398.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EMC97398.1 - 0.075 11.6 0.4 3.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EMC97398.1 - 0.18 10.2 4.0 0.39 9.1 0.2 2.5 3 0 0 3 3 3 0 HI0933-like protein Xpo1 PF08389.7 EMC97399.1 - 1.5e-06 28.1 1.1 6.8e-06 26.0 0.1 2.7 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EMC97399.1 - 0.46 10.6 5.8 4.4 7.6 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat Phosphodiest PF01663.17 EMC97401.1 - 7.2e-18 65.0 0.6 2.8e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMC97401.1 - 0.00021 20.6 0.0 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 Sulfatase PigN PF04987.9 EMC97401.1 - 0.0065 15.1 0.2 0.0065 15.1 0.2 2.6 3 0 0 3 3 3 1 Phosphatidylinositolglycan class N (PIG-N) Metalloenzyme PF01676.13 EMC97401.1 - 0.2 10.9 0.1 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily RRM_2 PF04059.7 EMC97402.1 - 9e-26 89.7 0.0 1.6e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EMC97402.1 - 8.8e-05 22.0 0.1 0.00056 19.4 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC97402.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.7 EMC97403.1 - 2.1e-97 326.2 1.3 3.1e-97 325.6 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 EMC97403.1 - 8.4e-05 22.4 3.8 8.4e-05 22.4 2.7 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 EMC97403.1 - 8.7e-05 22.4 7.2 9.3e-05 22.3 3.1 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 EMC97403.1 - 0.0014 18.2 4.3 0.0014 18.2 3.0 3.5 5 0 0 5 5 5 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EMC97403.1 - 0.013 14.4 5.5 0.028 13.3 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EMC97403.1 - 0.088 12.5 4.4 0.086 12.5 0.8 2.6 2 1 0 2 2 2 0 Exocyst complex component Sec5 Tom7 PF08038.7 EMC97404.1 - 4.5e-19 67.6 0.1 5e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 TOM7 family DUF2360 PF10152.4 EMC97405.1 - 0.14 12.4 0.3 0.16 12.2 0.2 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) RRM_1 PF00076.17 EMC97406.1 - 1e-30 105.1 0.0 2.3e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC97406.1 - 2.7e-17 62.4 0.0 2.5e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC97406.1 - 3.4e-12 46.0 0.0 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EMC97406.1 - 0.078 12.4 0.4 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF663 PF04950.7 EMC97406.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF663) DUF2015 PF09435.5 EMC97407.1 - 1.6e-41 141.0 2.7 9.1e-40 135.3 1.9 2.0 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2015) IN_DBD_C PF00552.16 EMC97408.1 - 0.037 13.4 0.1 0.084 12.3 0.1 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain CPG4 PF15481.1 EMC97409.1 - 0.15 12.4 2.6 0.15 12.4 1.0 1.5 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 ALAD PF00490.16 EMC97410.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase BAR PF03114.13 EMC97413.1 - 3.6e-44 150.9 8.0 4e-44 150.8 5.6 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EMC97413.1 - 2.8e-05 23.2 3.4 3.2e-05 22.9 2.4 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking RAB3GAP2_C PF14656.1 EMC97413.1 - 0.014 13.5 0.7 0.016 13.3 0.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus MscS_TM PF12794.2 EMC97413.1 - 0.086 11.4 2.0 0.13 10.8 1.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1501 PF07394.7 EMC97413.1 - 1.1 8.0 5.5 0.81 8.4 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1501) zf-CCCH PF00642.19 EMC97414.1 - 0.0036 16.9 0.9 0.0036 16.9 0.6 1.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CorA PF01544.13 EMC97415.1 - 5.4e-05 22.3 5.8 0.00026 20.1 4.0 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2721 PF11026.3 EMC97415.1 - 0.0056 16.3 1.1 0.43 10.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2721) Adap_comp_sub PF00928.16 EMC97416.1 - 1.4e-85 286.5 0.0 1.8e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMC97416.1 - 0.03 14.0 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Ras PF00071.17 EMC97418.1 - 1.4e-46 157.8 0.2 1.6e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC97418.1 - 2.9e-14 53.6 0.1 3.7e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC97418.1 - 3.1e-08 33.0 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC97418.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC97418.1 - 1.4e-05 24.5 0.3 0.00021 20.8 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC97418.1 - 4e-05 22.9 0.1 5.4e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EMC97418.1 - 0.00015 21.1 0.0 0.0038 16.5 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 EMC97418.1 - 0.043 13.7 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Elf1 PF05129.8 EMC97420.1 - 1.3e-24 85.7 1.1 1.6e-24 85.3 0.8 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 EMC97420.1 - 0.019 14.3 0.3 0.025 13.9 0.2 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF678 PF05077.7 EMC97420.1 - 0.72 9.8 4.3 6.2 6.8 3.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF678) Stm1_N PF09598.5 EMC97420.1 - 1.5 9.5 8.3 0.13 12.9 1.3 2.1 2 0 0 2 2 2 0 Stm1 GTP_CH_N PF12471.3 EMC97421.1 - 2.7e-90 301.2 0.0 3.9e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EMC97421.1 - 1.8e-16 59.8 0.0 3.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II Pro_isomerase PF00160.16 EMC97422.1 - 2e-35 122.3 0.0 6.6e-35 120.6 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lyase_N PF09092.6 EMC97422.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Lyase, N terminal Blt1 PF12754.2 EMC97423.1 - 1.8e-26 93.4 10.7 3.4e-25 89.2 7.4 2.1 1 1 0 1 1 1 1 Cell-cycle control medial ring component ubiquitin PF00240.18 EMC97423.1 - 9.3e-05 21.7 0.1 0.00016 20.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMC97423.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pol_alpha_B_N PF08418.5 EMC97423.1 - 0.17 11.3 4.7 0.11 11.9 2.4 1.4 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Herpes_UL32 PF06070.6 EMC97423.1 - 0.83 8.0 9.8 0.98 7.7 6.8 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DER1 PF04511.10 EMC97424.1 - 2.2e-50 170.9 5.2 2.5e-50 170.7 3.6 1.0 1 0 0 1 1 1 1 Der1-like family PAP2 PF01569.16 EMC97424.1 - 0.0079 15.8 2.8 0.0079 15.8 1.9 1.9 1 1 1 2 2 2 1 PAP2 superfamily Histone PF00125.19 EMC97425.1 - 1.4e-28 98.8 0.5 1.9e-28 98.3 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC97425.1 - 0.00017 21.7 0.1 0.00024 21.2 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC97425.1 - 0.0046 16.9 1.0 0.0091 16.0 0.7 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EMC97425.1 - 0.019 14.1 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EMC97425.1 - 0.089 12.5 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Flavin_Reduct PF01613.13 EMC97426.1 - 2.6e-20 72.8 0.0 3.6e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain HECT PF00632.20 EMC97426.1 - 0.091 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Ribosomal_L2_C PF03947.13 EMC97427.1 - 2e-37 127.8 4.1 2e-37 127.8 2.9 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMC97427.1 - 1.7e-13 50.3 0.1 3.6e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.1 EMC97428.1 - 0.0043 16.9 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 EMC97428.1 - 2.3 6.0 10.8 3.7 5.3 7.5 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2404 PF10296.4 EMC97429.1 - 7.4e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) T2SM PF04612.7 EMC97429.1 - 0.21 11.3 0.1 0.21 11.3 0.0 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M MFS_1 PF07690.11 EMC97430.1 - 1.6e-22 79.7 46.5 2.3e-22 79.2 32.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SBF PF01758.11 EMC97431.1 - 8.2e-46 155.7 12.9 8.2e-46 155.7 9.0 2.0 3 0 0 3 3 3 1 Sodium Bile acid symporter family FMN_red PF03358.10 EMC97433.1 - 5.3e-24 84.4 0.0 1.1e-23 83.4 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase E1-E2_ATPase PF00122.15 EMC97434.1 - 9e-15 54.3 5.0 1.7e-07 30.5 0.2 2.2 1 1 1 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 EMC97434.1 - 4.7e-13 50.0 0.0 8.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC97434.1 - 0.0041 17.2 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HEV_ORF1 PF02444.11 EMC97434.1 - 0.33 11.1 4.2 1.2 9.3 1.1 2.7 1 1 1 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) adh_short PF00106.20 EMC97435.1 - 2.3e-19 69.9 0.0 4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC97435.1 - 3e-09 36.8 0.0 6.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC97435.1 - 9.5e-08 31.7 0.0 1.9e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC97435.1 - 3.6e-05 23.8 0.1 6.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC97435.1 - 7.8e-05 21.6 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EMC97435.1 - 0.00011 21.4 0.1 0.0002 20.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMC97435.1 - 0.0031 16.4 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Fork_head PF00250.13 EMC97436.1 - 4.4e-33 113.1 0.1 7.2e-33 112.5 0.1 1.3 1 0 0 1 1 1 1 Fork head domain PhyH PF05721.8 EMC97438.1 - 2e-08 34.5 0.2 9e-08 32.3 0.1 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.14 EMC97438.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain P21-Arc PF04062.9 EMC97439.1 - 4.2e-78 261.1 0.0 4.7e-78 260.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DDE_5 PF13546.1 EMC97439.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1399 PF07173.7 EMC97440.1 - 4.4e-24 85.3 1.6 1.7e-17 64.0 0.1 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF1399) Kelch_6 PF13964.1 EMC97441.1 - 0.00018 21.5 1.4 0.49 10.6 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EMC97441.1 - 0.00025 20.9 0.4 0.34 10.9 0.0 3.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 EMC97441.1 - 0.00031 20.4 8.4 0.1 12.3 0.1 4.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC97441.1 - 0.0027 17.8 9.6 1.4 9.1 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain DUF347 PF03988.7 EMC97441.1 - 0.049 13.5 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) peroxidase PF00141.18 EMC97442.1 - 5.6e-15 55.4 0.0 1e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 Peroxidase DUF1421 PF07223.6 EMC97444.1 - 0.69 9.6 8.8 0.92 9.2 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Aldo_ket_red PF00248.16 EMC97445.1 - 7.1e-44 149.7 0.0 8.6e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ydc2-catalyt PF09159.5 EMC97446.1 - 8.9e-60 202.5 0.0 1.1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EMC97446.1 - 0.00071 19.4 0.0 0.3 10.9 0.0 3.1 3 0 0 3 3 3 1 Poxvirus A22 protein SAP PF02037.22 EMC97446.1 - 0.041 13.3 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 SAP domain LsmAD PF06741.8 EMC97447.1 - 1.3e-26 92.4 2.5 1.3e-26 92.4 1.8 2.5 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EMC97447.1 - 2.6e-10 40.0 0.2 6e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LAT PF15234.1 EMC97448.1 - 1.5 8.2 5.6 1.7 8.0 3.9 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells AIP3 PF03915.8 EMC97450.1 - 1.1e-133 446.2 0.1 2.6e-133 445.0 0.0 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 HSBP1 PF06825.7 EMC97450.1 - 0.026 14.0 0.0 0.095 12.2 0.0 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.6 EMC97450.1 - 4.1 7.8 7.5 5.6 7.4 0.8 3.7 2 1 2 4 4 4 0 Syntaxin 6, N-terminal adh_short PF00106.20 EMC97451.1 - 4.8e-29 101.4 0.9 6.4e-29 101.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97451.1 - 3.8e-25 89.0 0.3 4.6e-25 88.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97451.1 - 1.1e-16 60.9 0.7 1.7e-16 60.4 0.5 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMC97451.1 - 0.00011 21.0 0.1 0.00018 20.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMC97451.1 - 0.0024 16.8 0.0 0.0035 16.2 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EMC97451.1 - 0.0044 16.4 0.5 0.016 14.6 0.4 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACP53EA PF06313.6 EMC97451.1 - 0.084 12.8 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Drosophila ACP53EA protein UDPG_MGDP_dh_C PF03720.10 EMC97451.1 - 0.095 12.8 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Med5 PF08689.5 EMC97452.1 - 1.9e-119 399.9 0.0 2.3e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Aa_trans PF01490.13 EMC97454.1 - 2.5e-76 256.8 28.1 2.9e-76 256.5 19.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Nanovirus_C8 PF05629.6 EMC97454.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein Epimerase PF01370.16 EMC97455.1 - 6.6e-09 35.5 0.3 0.0022 17.4 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC97455.1 - 5.7e-05 21.9 0.0 0.0072 15.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMC97455.1 - 0.00015 22.0 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EMC97455.1 - 0.0014 17.8 0.1 0.0021 17.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EMC97455.1 - 0.023 13.6 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF2285 PF10074.4 EMC97455.1 - 0.037 14.3 0.1 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) Sec23_trunk PF04811.10 EMC97458.1 - 3.9e-80 268.7 0.0 6.1e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMC97458.1 - 2.4e-34 116.8 0.2 5.3e-34 115.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMC97458.1 - 2.1e-29 101.8 0.1 5.1e-29 100.6 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMC97458.1 - 9.4e-17 60.2 6.5 1.9e-16 59.2 4.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMC97458.1 - 9.5e-12 44.4 0.0 2.2e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat RasGEF PF00617.14 EMC97459.1 - 2.4e-56 190.4 0.1 8.5e-56 188.6 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EMC97459.1 - 1.2e-19 70.3 0.0 5.4e-19 68.2 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 EMC97459.1 - 0.00014 21.3 0.0 0.00032 20.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC97459.1 - 0.00016 20.9 0.0 0.00049 19.4 0.0 1.9 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC97459.1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF3237 PF11578.3 EMC97460.1 - 4.3e-09 35.8 0.0 5.5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ALAD PF00490.16 EMC97464.1 - 1e-117 392.6 0.0 1.2e-117 392.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PEP_mutase PF13714.1 EMC97464.1 - 0.14 11.3 2.0 2.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase Ima1_N PF09779.4 EMC97465.1 - 2.4e-36 125.1 5.0 4.5e-36 124.2 3.5 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF4293 PF14126.1 EMC97465.1 - 0.0066 16.3 0.5 0.09 12.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) FYVE PF01363.16 EMC97465.1 - 0.23 11.3 7.3 1.3 8.9 5.0 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-FPG_IleRS PF06827.9 EMC97465.1 - 0.24 11.0 3.0 10 5.8 0.1 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Mito_carr PF00153.22 EMC97466.1 - 2.6e-43 145.6 4.8 1.7e-14 53.3 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein IU_nuc_hydro PF01156.14 EMC97468.1 - 2.6e-23 82.7 0.0 2.9e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SnoaL_4 PF13577.1 EMC97469.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain 4HBT PF03061.17 EMC97471.1 - 1.7e-12 47.3 0.1 1.9e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 Thioesterase superfamily DUF1680 PF07944.7 EMC97471.1 - 0.076 11.2 0.0 0.085 11.1 0.0 1.0 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) CytoC_RC PF02276.13 EMC97471.1 - 0.083 11.9 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit FAD_binding_3 PF01494.14 EMC97472.1 - 2.6e-16 59.6 0.0 4.5e-16 58.8 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC97472.1 - 3.2e-09 36.1 0.7 8e-06 24.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC97472.1 - 9.4e-06 25.9 0.5 0.00012 22.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC97472.1 - 9.2e-05 22.3 0.2 0.0002 21.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 EMC97472.1 - 0.00041 19.8 0.2 0.00072 19.0 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EMC97472.1 - 0.00049 19.0 0.9 0.00084 18.2 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC97472.1 - 0.0022 17.9 0.3 0.0057 16.5 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMC97472.1 - 0.0047 16.5 0.2 0.011 15.2 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EMC97472.1 - 0.0063 15.1 0.1 1.6 7.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase 3HCDH_N PF02737.13 EMC97472.1 - 0.023 14.3 0.3 0.041 13.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EMC97472.1 - 0.064 12.1 0.4 0.12 11.2 0.2 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EMC97472.1 - 0.092 12.4 0.5 0.22 11.2 0.2 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 EMC97472.1 - 0.18 11.8 1.1 1.3 9.0 0.3 2.5 3 0 0 3 3 3 0 NADH(P)-binding WD40 PF00400.27 EMC97473.1 - 1.5e-19 69.0 6.7 8.2e-06 25.5 0.2 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat LEA_2 PF03168.8 EMC97474.1 - 8.7e-05 22.8 4.2 0.0059 16.9 0.1 4.9 6 0 0 6 6 6 1 Late embryogenesis abundant protein OTCace PF00185.19 EMC97475.1 - 3.9e-42 143.8 0.0 6.1e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EMC97475.1 - 8.5e-42 142.1 0.3 1.3e-41 141.5 0.2 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ALS_ss_C PF10369.4 EMC97476.1 - 7.8e-18 63.9 0.0 6.2e-17 61.0 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EMC97476.1 - 2e-12 46.3 0.1 3.4e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EMC97476.1 - 1.3e-09 37.7 0.5 2.3e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 EMC97476.1 - 0.11 12.1 0.1 19 5.0 0.0 2.4 2 0 0 2 2 2 0 ACT domain Gly-zipper_OmpA PF13436.1 EMC97476.1 - 5.6 6.6 7.8 16 5.1 0.6 2.3 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain KH_1 PF00013.24 EMC97477.1 - 2.4e-11 43.1 0.1 3e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EMC97477.1 - 1.1e-06 28.1 1.0 0.00017 21.1 0.1 2.9 2 0 0 2 2 2 2 KH domain Pkinase PF00069.20 EMC97478.1 - 7.2e-16 58.1 0.0 1.4e-15 57.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97478.1 - 5.4e-10 38.7 0.0 3.8e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMC97478.1 - 0.044 13.4 0.8 0.11 12.2 0.1 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family UPF0160 PF03690.8 EMC97479.1 - 2.1e-113 378.9 0.0 4.1e-113 377.9 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) Tyrosinase PF00264.15 EMC97480.1 - 2.2e-55 188.2 0.5 5.2e-55 187.0 0.4 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase Guanylate_kin PF00625.16 EMC97482.1 - 1.3e-64 217.0 0.0 1.4e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EMC97482.1 - 1.4e-08 34.9 0.0 2.6e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EMC97482.1 - 3.8e-08 33.3 0.0 1.3e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC97482.1 - 4.5e-07 30.2 0.0 1.2e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC97482.1 - 2.3e-06 28.4 0.0 6.7e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC97482.1 - 2.4e-06 27.7 0.0 1.6e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMC97482.1 - 3.1e-05 24.0 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMC97482.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC97482.1 - 0.00019 20.6 0.0 0.00027 20.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMC97482.1 - 0.00023 20.7 0.2 0.0005 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EMC97482.1 - 0.00042 20.6 0.0 0.0007 19.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 EMC97482.1 - 0.00075 19.9 0.0 0.0017 18.8 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 EMC97482.1 - 0.00088 19.1 0.0 0.0014 18.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 EMC97482.1 - 0.0016 17.8 0.1 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EMC97482.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.1 EMC97482.1 - 0.0023 18.2 0.3 0.067 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EMC97482.1 - 0.0029 17.3 1.4 0.017 14.8 1.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 EMC97482.1 - 0.0081 15.1 0.1 0.14 11.0 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EMC97482.1 - 0.0081 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EMC97482.1 - 0.0083 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein cobW PF02492.14 EMC97482.1 - 0.0092 15.4 0.1 0.039 13.4 0.0 1.9 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 EMC97482.1 - 0.013 14.8 0.3 1.2 8.5 0.0 2.4 1 1 1 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 EMC97482.1 - 0.014 14.4 0.2 0.043 12.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EMC97482.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ADK PF00406.17 EMC97482.1 - 0.022 14.6 0.2 0.83 9.5 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase Viral_helicase1 PF01443.13 EMC97482.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EMC97482.1 - 0.025 14.2 0.1 0.077 12.7 0.0 2.0 1 1 0 1 1 1 0 NTPase MobB PF03205.9 EMC97482.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA12 PF10443.4 EMC97482.1 - 0.051 12.0 1.3 0.54 8.6 0.0 2.2 2 1 0 2 2 2 0 RNA12 protein CPT PF07931.7 EMC97482.1 - 0.055 13.0 0.1 0.29 10.7 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Gtr1_RagA PF04670.7 EMC97482.1 - 0.064 12.3 0.0 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.9 EMC97482.1 - 0.07 12.8 0.2 0.46 10.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF1895 PF08988.5 EMC97482.1 - 0.083 12.9 0.1 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) AAA_24 PF13479.1 EMC97482.1 - 0.1 12.1 0.2 0.64 9.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EMC97482.1 - 0.12 11.8 0.1 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 EMC97482.1 - 0.14 12.3 0.3 0.51 10.5 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PP2C PF00481.16 EMC97483.1 - 9.7e-82 274.1 0.0 1.2e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMC97483.1 - 0.00067 19.1 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C CTP_transf_2 PF01467.21 EMC97484.1 - 3.6e-20 72.5 0.0 7.4e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EMC97484.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase Tcp11 PF05794.8 EMC97485.1 - 5.7e-81 272.4 0.0 7.8e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 WD40 PF00400.27 EMC97486.1 - 3.1e-55 182.1 12.8 2.4e-12 46.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMC97486.1 - 7.8e-05 22.1 0.0 0.12 11.8 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2256 PF10013.4 EMC97488.1 - 0.32 10.7 0.5 0.32 10.7 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DEAD PF00270.24 EMC97489.1 - 3.7e-19 68.8 0.0 1.1e-18 67.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC97489.1 - 1.8e-17 62.9 0.0 1.1e-13 50.7 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMC97489.1 - 0.00069 18.5 0.1 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain PPR_3 PF13812.1 EMC97490.1 - 9.6e-17 59.8 2.3 0.0052 16.9 0.0 5.9 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EMC97490.1 - 2e-14 53.2 0.1 7.1e-05 22.6 0.0 5.1 3 2 1 4 4 4 4 PPR repeat family PPR PF01535.15 EMC97490.1 - 4.6e-10 38.7 3.6 0.1 12.6 0.0 6.2 7 0 0 7 7 7 3 PPR repeat BTAD PF03704.12 EMC97490.1 - 0.0016 18.7 0.9 0.0079 16.5 0.0 2.6 3 0 0 3 3 3 1 Bacterial transcriptional activator domain PPR_1 PF12854.2 EMC97490.1 - 0.0058 16.0 0.9 4.4 6.8 0.0 4.0 4 0 0 4 4 4 1 PPR repeat DUF2411 PF10304.4 EMC97490.1 - 0.014 14.9 0.1 0.075 12.5 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF2411) T2SF PF00482.18 EMC97490.1 - 0.024 14.5 0.2 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Sec1 PF00995.18 EMC97490.1 - 0.07 11.7 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Sec1 family MRP-S25 PF13741.1 EMC97491.1 - 2.6e-49 167.7 11.2 8.9e-26 90.7 0.3 3.1 1 1 2 3 3 3 3 Mitochondrial ribosomal protein S25 GRAB PF10375.4 EMC97493.1 - 5.3e-09 35.3 0.1 1e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.16 EMC97493.1 - 0.00019 20.9 46.0 0.0025 17.3 7.4 4.0 1 1 3 4 4 4 2 Intermediate filament protein Reo_sigmaC PF04582.7 EMC97493.1 - 0.00033 19.9 13.2 0.3 10.2 0.1 3.1 2 1 1 3 3 3 3 Reovirus sigma C capsid protein Rootletin PF15035.1 EMC97493.1 - 0.00053 20.0 47.8 0.12 12.3 7.3 3.5 2 1 1 3 3 3 2 Ciliary rootlet component, centrosome cohesion WEMBL PF05701.6 EMC97493.1 - 0.0012 17.3 47.3 0.002 16.6 13.9 2.2 1 1 0 2 2 2 2 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 EMC97493.1 - 0.0045 14.7 57.4 0.0059 14.4 33.5 2.0 1 1 1 2 2 2 1 Myosin tail Atg14 PF10186.4 EMC97493.1 - 0.0059 15.5 7.8 0.0059 15.5 5.4 3.3 1 1 1 3 3 3 1 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 EMC97493.1 - 0.017 14.8 0.8 0.017 14.8 0.6 5.2 5 1 0 5 5 5 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EMC97493.1 - 0.04 13.6 51.4 0.13 11.9 14.4 4.2 1 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 EMC97493.1 - 0.049 10.9 51.6 0.27 8.5 15.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 EMC97493.1 - 0.073 13.3 16.7 1.8 8.8 0.2 4.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_27 PF13514.1 EMC97493.1 - 0.076 10.6 46.1 0.3 8.7 13.2 2.8 1 1 2 3 3 3 0 AAA domain DUF1464 PF07318.7 EMC97493.1 - 0.15 10.8 0.8 0.3 9.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Phage_GP20 PF06810.6 EMC97493.1 - 0.33 10.3 42.0 0.25 10.7 4.4 3.8 2 2 2 4 4 4 0 Phage minor structural protein GP20 Laminin_II PF06009.7 EMC97493.1 - 0.36 10.5 29.1 0.32 10.7 4.7 3.4 2 1 1 3 3 3 0 Laminin Domain II IncA PF04156.9 EMC97493.1 - 0.38 10.3 60.7 0.25 10.8 15.0 3.5 1 1 2 3 3 3 0 IncA protein DUF1664 PF07889.7 EMC97493.1 - 0.4 10.4 22.4 0.25 11.1 2.1 4.0 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EMC97493.1 - 0.69 9.7 56.0 0.71 9.7 11.4 3.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DcpS_C PF11969.3 EMC97493.1 - 0.7 10.1 3.3 25 5.1 0.5 2.6 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding DUF972 PF06156.8 EMC97493.1 - 0.95 9.8 35.5 0.24 11.7 3.6 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF972) Tweety PF04906.8 EMC97493.1 - 1.3 7.3 11.4 0.29 9.5 1.3 2.6 2 1 0 2 2 2 0 Tweety Mnd1 PF03962.10 EMC97493.1 - 1.8 8.1 44.3 0.33 10.6 8.7 3.2 1 1 2 3 3 3 0 Mnd1 family IFT57 PF10498.4 EMC97493.1 - 1.8 7.2 39.7 4 6.0 12.6 2.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Prefoldin PF02996.12 EMC97493.1 - 1.9 8.1 31.9 2.9 7.5 4.3 5.4 2 2 3 5 5 5 0 Prefoldin subunit CENP-Q PF13094.1 EMC97493.1 - 2.6 8.0 55.3 0.064 13.2 12.9 3.4 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 EMC97493.1 - 3.9 6.4 49.1 0.31 10.0 15.0 2.7 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF2935 PF11155.3 EMC97493.1 - 4.1 7.5 9.5 2.1 8.4 0.4 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF2935) Spc7 PF08317.6 EMC97493.1 - 4.2 5.9 43.8 0.025 13.2 9.5 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein COG5 PF10392.4 EMC97493.1 - 4.6 7.2 25.8 0.62 10.0 4.1 3.8 2 2 2 4 4 4 0 Golgi transport complex subunit 5 IFT46_B_C PF12317.3 EMC97493.1 - 5 6.4 9.1 0.28 10.5 1.6 2.1 2 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Bap31 PF05529.7 EMC97493.1 - 5.4 6.4 33.3 4.4 6.7 2.8 3.6 2 2 1 3 3 3 0 B-cell receptor-associated protein 31-like ApoO PF09769.4 EMC97493.1 - 6.8 6.3 9.6 21 4.8 0.4 3.7 1 1 1 2 2 2 0 Apolipoprotein O Lebercilin PF15619.1 EMC97493.1 - 7.3 5.9 51.7 2.4 7.5 17.8 3.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.4 EMC97493.1 - 8.5 6.5 23.7 1.6 8.9 3.8 3.8 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 EMC97493.1 - 9.2 6.1 51.1 3.8 7.3 9.9 3.9 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding WXG100 PF06013.7 EMC97493.1 - 9.2 6.3 26.6 8.3 6.4 0.1 5.3 2 2 2 4 4 4 0 Proteins of 100 residues with WXG DUF4618 PF15397.1 EMC97493.1 - 9.8 5.4 35.1 0.59 9.4 8.0 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) WD40 PF00400.27 EMC97495.1 - 3.8e-29 99.4 12.9 4.1e-09 35.9 0.0 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EMC97495.1 - 0.00045 18.4 6.9 0.39 8.7 0.1 4.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC97495.1 - 0.039 12.7 0.1 0.88 8.2 0.1 2.6 1 1 1 2 2 2 0 Nup133 N terminal like Ribosomal_L31e PF01198.14 EMC97496.1 - 6.2e-18 64.2 0.2 7.8e-18 63.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e PP2C PF00481.16 EMC97497.1 - 3.4e-38 131.5 0.0 6.2e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMC97497.1 - 0.025 14.2 0.1 2.9 7.5 0.0 2.9 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EMC97497.1 - 0.04 13.3 0.1 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C Tetraspannin PF00335.15 EMC97498.1 - 0.49 9.6 8.0 9.2 5.4 0.0 2.5 2 1 0 2 2 2 0 Tetraspanin family Clc-like PF07062.7 EMC97498.1 - 6.9 5.8 11.5 0.9 8.7 0.2 2.6 1 1 2 3 3 3 0 Clc-like PNK3P PF08645.6 EMC97501.1 - 7.3e-55 184.7 0.0 1.3e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EMC97501.1 - 8e-28 97.1 0.0 5.9e-27 94.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain HAD_2 PF13419.1 EMC97501.1 - 2e-05 24.8 1.2 0.0027 17.9 0.0 3.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase KTI12 PF08433.5 EMC97501.1 - 0.0022 17.2 0.4 0.8 8.8 0.0 2.6 2 1 1 3 3 3 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EMC97501.1 - 0.0077 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Hydrolase_like PF13242.1 EMC97501.1 - 0.035 13.8 0.1 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like AAA_29 PF13555.1 EMC97501.1 - 0.098 12.2 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EMC97501.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SUR7 PF06687.7 EMC97502.1 - 1.5e-45 155.3 19.5 1.8e-45 155.0 13.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EMC97502.1 - 0.58 10.0 15.3 0.45 10.3 8.6 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3357 PF11837.3 EMC97502.1 - 0.8 9.5 0.0 0.8 9.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF1712 PF08217.6 EMC97504.1 - 4.9e-18 64.7 0.0 1.6e-15 56.3 0.0 2.6 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) ABC2_membrane PF01061.19 EMC97505.1 - 3e-96 320.6 58.6 4e-51 173.1 18.2 2.8 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EMC97505.1 - 1.1e-36 126.1 0.0 2e-17 63.7 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EMC97505.1 - 2.2e-34 117.1 2.2 1.5e-32 111.3 0.0 3.9 5 0 0 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EMC97505.1 - 8.3e-21 73.8 0.0 2.3e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 EMC97505.1 - 4.6e-08 33.0 0.1 0.0013 18.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMC97505.1 - 1.4e-06 27.8 0.1 0.00021 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMC97505.1 - 1.2e-05 24.5 0.1 0.00046 19.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMC97505.1 - 0.00016 21.7 3.1 0.0016 18.4 0.1 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.1 EMC97505.1 - 0.00023 20.6 1.2 0.023 14.1 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EMC97505.1 - 0.00027 20.4 0.4 0.011 15.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EMC97505.1 - 0.00052 20.8 0.0 0.072 13.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMC97505.1 - 0.0034 16.6 0.0 0.55 9.4 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EMC97505.1 - 0.0071 16.6 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMC97505.1 - 0.0071 16.4 0.1 2.2 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC97505.1 - 0.017 14.8 1.2 4.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EMC97505.1 - 0.029 14.0 0.6 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EMC97505.1 - 0.044 13.7 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMC97505.1 - 0.048 13.2 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMC97505.1 - 0.19 11.3 0.7 3.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EMC97505.1 - 0.22 10.9 0.5 8.4 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain GARS_A PF01071.14 EMC97506.1 - 3.7e-84 281.1 0.0 4.9e-84 280.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EMC97506.1 - 1.3e-33 115.4 0.0 2.5e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EMC97506.1 - 4e-29 100.6 0.2 8.3e-29 99.6 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 EMC97506.1 - 1.7e-13 50.6 0.0 3.8e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC97506.1 - 1.5e-08 33.7 0.0 4.8e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMC97506.1 - 2.7e-06 26.8 0.0 5.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMC97506.1 - 2e-05 24.4 0.0 4.4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EMC97506.1 - 0.00014 21.2 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EMC97506.1 - 0.0057 16.1 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMC97506.1 - 0.0088 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DUF544 PF04424.8 EMC97507.1 - 3.7e-14 52.5 0.0 6.5e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) PIG-X PF08320.7 EMC97508.1 - 4.4e-65 218.8 0.0 8e-65 217.9 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 Fcf2 PF08698.6 EMC97509.1 - 1.6e-29 101.8 0.1 1.6e-29 101.8 0.1 2.0 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.15 EMC97510.1 - 1.2e-50 171.7 0.1 1.5e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.17 EMC97511.1 - 6.7e-23 80.3 0.0 1.7e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Aconitase PF00330.15 EMC97512.1 - 2.9e-155 517.2 0.0 1.8e-154 514.6 0.0 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMC97512.1 - 1.6e-39 135.0 0.0 2.4e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Endosulfine PF04667.12 EMC97513.1 - 2.1e-22 78.9 1.3 2.8e-22 78.4 0.4 1.6 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 EMC97514.1 - 4.9e-37 127.2 0.0 6.6e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase AAA_17 PF13207.1 EMC97515.1 - 5e-07 30.5 0.3 4.8e-06 27.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EMC97515.1 - 6.4e-06 25.8 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EMC97515.1 - 2e-05 23.7 0.2 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EMC97515.1 - 3.3e-05 23.7 0.1 0.00051 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EMC97515.1 - 4.1e-05 22.5 0.0 6.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 EMC97515.1 - 0.00014 21.5 0.2 0.00047 19.8 0.1 2.0 1 1 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EMC97515.1 - 0.00016 21.9 0.1 0.0014 18.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMC97515.1 - 0.00021 21.4 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC97515.1 - 0.0003 20.8 0.0 0.00045 20.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.12 EMC97515.1 - 0.0011 18.3 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA PF00004.24 EMC97515.1 - 0.0014 18.8 0.0 0.0041 17.3 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EMC97515.1 - 0.0019 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMC97515.1 - 0.0024 17.5 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RuvB_N PF05496.7 EMC97515.1 - 0.0042 16.1 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EMC97515.1 - 0.005 15.7 0.0 0.0087 14.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.10 EMC97515.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.1 EMC97515.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EMC97515.1 - 0.013 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EMC97515.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EMC97515.1 - 0.021 14.7 0.0 0.93 9.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase APS_kinase PF01583.15 EMC97515.1 - 0.021 14.4 0.0 0.054 13.1 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.4 EMC97515.1 - 0.023 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EMC97515.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EMC97515.1 - 0.034 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EMC97515.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_31 PF13614.1 EMC97515.1 - 0.044 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMC97515.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EMC97515.1 - 0.057 12.1 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 EMC97515.1 - 0.075 12.4 0.4 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.1 EMC97515.1 - 0.098 12.2 0.0 0.098 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC97515.1 - 0.099 12.9 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 EMC97515.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EMC97515.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.18 EMC97515.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 EMC97515.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF1761 PF08570.5 EMC97516.1 - 1.6e-24 86.3 3.1 1.8e-24 86.1 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) HATPase_c_3 PF13589.1 EMC97518.1 - 8.1e-14 51.4 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EMC97518.1 - 8.1e-07 28.7 0.0 0.0089 15.6 0.0 3.4 3 0 0 3 3 3 2 MutL C terminal dimerisation domain HATPase_c PF02518.21 EMC97518.1 - 2.2e-05 24.1 0.0 5e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3408 PF11888.3 EMC97518.1 - 0.38 10.6 2.9 0.26 11.2 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3408) bZIP_1 PF00170.16 EMC97520.1 - 0.00011 22.0 13.3 0.00016 21.5 9.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC97520.1 - 0.016 15.0 13.9 0.021 14.6 9.6 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Ribosomal_S20p PF01649.13 EMC97520.1 - 0.045 14.1 6.2 0.073 13.4 4.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 NPIP PF06409.6 EMC97520.1 - 0.074 11.7 2.1 0.1 11.3 1.5 1.1 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) DUF4570 PF15134.1 EMC97520.1 - 0.16 11.8 5.8 0.26 11.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF4407 PF14362.1 EMC97520.1 - 0.67 8.8 3.7 0.94 8.3 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 EMC97520.1 - 1.9 8.0 5.1 4.2 6.9 3.5 1.6 1 1 0 1 1 1 0 Septum formation initiator Kin17_mid PF10357.4 EMC97521.1 - 1.4e-48 163.7 0.1 2.3e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EMC97521.1 - 2.4e-05 24.3 1.7 4.9e-05 23.3 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC97521.1 - 0.0024 18.0 1.5 0.0043 17.2 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC97521.1 - 0.0042 17.1 2.8 0.015 15.3 0.3 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Phage_B PF02304.10 EMC97521.1 - 0.22 11.8 1.6 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Scaffold protein B zf-C2H2_4 PF13894.1 EMC97521.1 - 0.22 11.9 0.7 0.46 10.9 0.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger MCPVI PF02993.9 EMC97521.1 - 1.3 9.0 7.2 2.2 8.3 5.0 1.3 1 0 0 1 1 1 0 Minor capsid protein VI MFS_1 PF07690.11 EMC97522.1 - 1.4e-33 116.1 29.3 3.4e-32 111.5 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EMC97523.1 - 4.1e-40 137.5 57.1 4.1e-40 137.5 39.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC97523.1 - 1.3e-11 43.3 29.4 2.5e-11 42.4 20.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC97523.1 - 2.4e-10 39.5 18.3 2.4e-10 39.5 12.7 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter VQ PF05678.9 EMC97523.1 - 0.16 11.0 0.3 0.29 10.2 0.2 1.4 1 0 0 1 1 1 0 VQ motif DUF3989 PF13150.1 EMC97523.1 - 1.1 8.6 2.8 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF1183 PF06682.7 EMC97524.1 - 3e-85 286.6 6.4 1.9e-84 283.9 4.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) tRNA-synt_2b PF00587.20 EMC97525.1 - 1.6e-33 115.7 1.6 1.7e-33 115.6 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EMC97525.1 - 1.4e-14 54.0 6.1 1.4e-14 54.0 4.2 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EMC97525.1 - 0.92 9.1 8.4 0.11 12.1 2.9 1.7 2 0 0 2 2 2 0 Mnd1 family ICE2 PF08426.5 EMC97526.1 - 3.6e-134 447.4 3.9 4.2e-134 447.2 2.7 1.0 1 0 0 1 1 1 1 ICE2 ETC_C1_NDUFA5 PF04716.9 EMC97526.1 - 2 8.0 4.4 8.8 5.9 0.2 2.6 3 0 0 3 3 3 0 ETC complex I subunit conserved region adh_short PF00106.20 EMC97527.1 - 8.2e-20 71.3 0.3 1.1e-18 67.6 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97527.1 - 2.8e-18 66.5 0.0 4.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97527.1 - 3.1e-09 36.7 1.6 7.5e-08 32.2 0.0 2.1 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.13 EMC97527.1 - 0.15 11.6 0.4 0.42 10.2 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 EMC97527.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pkinase PF00069.20 EMC97528.1 - 3.4e-68 229.6 0.0 8.5e-68 228.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97528.1 - 8.4e-50 169.2 0.0 1.5e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC97528.1 - 0.00014 20.9 0.0 0.0005 19.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Arm PF00514.18 EMC97528.1 - 0.01 15.6 0.6 4.7 7.1 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat KAP PF05804.7 EMC97528.1 - 0.011 13.6 2.0 0.024 12.6 1.4 1.4 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EMC97528.1 - 0.079 12.0 5.0 1.6 7.7 1.4 2.8 2 1 0 2 2 2 0 V-ATPase subunit H RTTN_N PF14726.1 EMC97528.1 - 2.5 8.7 6.0 36 5.0 0.1 2.9 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning DnaJ PF00226.26 EMC97530.1 - 9.8e-20 70.0 0.4 1.5e-19 69.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF605 PF04652.11 EMC97532.1 - 0.25 10.6 16.8 0.29 10.4 11.6 1.0 1 0 0 1 1 1 0 Vta1 like LEA_4 PF02987.11 EMC97535.1 - 0.0003 20.5 0.8 1.2 9.1 0.9 2.6 2 0 0 2 2 2 2 Late embryogenesis abundant protein Ferritin PF00210.19 EMC97535.1 - 0.64 9.7 4.1 0.81 9.4 0.2 2.3 1 1 1 2 2 2 0 Ferritin-like domain Apolipoprotein PF01442.13 EMC97535.1 - 0.65 9.4 25.6 7.4 6.0 16.8 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain SDH_alpha PF03313.10 EMC97535.1 - 1.7 7.5 15.9 0.85 8.6 1.7 2.9 1 1 2 3 3 3 0 Serine dehydratase alpha chain UPF0278 PF08745.6 EMC97535.1 - 3.8 6.6 10.5 2.9 7.0 0.3 3.4 1 1 2 3 3 3 0 UPF0278 family Ribosomal_L17 PF01196.14 EMC97536.1 - 1.5e-33 115.2 0.0 3e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 TMP_2 PF06791.8 EMC97536.1 - 0.085 12.4 1.0 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 Prophage tail length tape measure protein DUF1719 PF08224.6 EMC97536.1 - 0.094 11.7 0.1 0.21 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) DUF2336 PF10098.4 EMC97536.1 - 0.14 11.3 4.2 0.24 10.6 0.5 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2336) ATP-synt_B PF00430.13 EMC97536.1 - 0.33 10.7 5.8 3.5 7.4 0.1 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Repressor_Mnt PF11423.3 EMC97536.1 - 0.41 9.9 2.9 0.66 9.3 0.3 2.6 2 0 0 2 2 2 0 Regulatory protein Mnt zf-RING_2 PF13639.1 EMC97538.1 - 1.1e-06 28.3 4.7 1.1e-06 28.3 3.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EMC97538.1 - 0.013 15.6 5.7 0.013 15.6 3.9 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMC97538.1 - 0.023 14.3 2.9 0.023 14.3 2.0 3.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC97538.1 - 0.15 12.1 21.5 0.15 12.0 2.9 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BUD22 PF09073.5 EMC97538.1 - 3.7 6.5 6.7 5.2 6.0 4.7 1.1 1 0 0 1 1 1 0 BUD22 zf-RING_5 PF14634.1 EMC97538.1 - 8 6.2 19.3 0.6 9.8 2.7 2.9 2 1 0 2 2 2 0 zinc-RING finger domain Myb_DNA-bind_6 PF13921.1 EMC97539.1 - 0.0088 16.1 0.8 0.024 14.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SBP PF03110.9 EMC97539.1 - 0.089 13.0 0.1 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 SBP domain COesterase PF00135.23 EMC97540.1 - 3.6e-92 309.7 1.5 4.4e-92 309.4 1.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC97540.1 - 1.3e-06 28.1 0.3 6.4e-06 25.8 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC97540.1 - 0.026 13.7 2.5 0.062 12.5 0.3 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3237 PF11578.3 EMC97541.1 - 8.9e-50 167.8 0.0 1.1e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) NAD_binding_8 PF13450.1 EMC97542.1 - 1.5e-12 47.3 0.2 3.8e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC97542.1 - 1.9e-09 36.9 0.0 4.5e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC97542.1 - 1.7e-07 31.3 0.1 0.00016 21.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMC97542.1 - 9.8e-07 28.1 0.1 0.00011 21.4 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMC97542.1 - 2.4e-06 27.8 0.2 0.12 12.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC97542.1 - 7.6e-06 24.6 0.5 0.0026 16.3 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 EMC97542.1 - 7.8e-06 25.7 0.1 0.00042 20.1 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EMC97542.1 - 1.1e-05 24.5 0.2 1.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC97542.1 - 1.2e-05 25.4 1.1 0.00013 22.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC97542.1 - 0.00068 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EMC97542.1 - 0.0026 16.8 0.1 0.0061 15.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EMC97542.1 - 0.011 15.9 0.6 0.18 12.1 0.0 2.6 2 1 1 3 3 3 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EMC97542.1 - 0.017 15.2 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EMC97542.1 - 0.068 12.2 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EMC97542.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EMC97542.1 - 0.14 11.9 0.1 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 ThiF family Ldh_1_N PF00056.18 EMC97542.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SPX PF03105.14 EMC97543.1 - 1.7e-30 106.7 8.8 4.9e-18 65.8 1.3 2.3 1 1 1 2 2 2 2 SPX domain Ank_2 PF12796.2 EMC97543.1 - 2.9e-28 98.0 4.8 1.2e-10 41.5 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC97543.1 - 7.5e-25 86.8 7.0 5.1e-11 42.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC97543.1 - 1.9e-16 58.9 13.0 8.5e-05 22.1 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EMC97543.1 - 5.5e-15 55.0 10.1 3.3e-05 23.9 0.0 6.6 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC97543.1 - 4.6e-13 48.0 10.0 0.00012 21.9 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat GDPD PF03009.12 EMC97543.1 - 1.3e-11 44.5 0.0 7.6e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family He_PIG PF05345.7 EMC97544.1 - 3.7e-18 65.2 14.2 2.6e-06 27.3 0.9 4.7 4 0 0 4 4 4 4 Putative Ig domain Methyltransf_16 PF10294.4 EMC97545.1 - 3.6e-33 114.4 0.0 1.5e-31 109.2 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Coa1 PF08695.5 EMC97548.1 - 1.4e-38 130.9 0.0 1.8e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2431 PF10354.4 EMC97549.1 - 1.4e-58 197.4 0.0 1.7e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 EMC97549.1 - 6.6e-05 22.9 0.0 8.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC97549.1 - 0.05 12.9 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Sedlin_N PF04628.8 EMC97550.1 - 8.5e-25 87.1 0.0 9.9e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Oxidored_q6 PF01058.17 EMC97551.1 - 1.2e-21 76.7 0.0 1.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TPR_16 PF13432.1 EMC97552.1 - 0.22 12.2 1.6 0.39 11.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_92 PF07971.7 EMC97554.1 - 3.9e-168 560.2 0.1 4.9e-168 559.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Steroid_dh PF02544.11 EMC97557.1 - 1.3e-15 57.4 0.3 2.3e-14 53.4 0.2 2.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1418 PF07214.7 EMC97557.1 - 0.14 11.7 0.1 0.4 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Fungal_trans PF04082.13 EMC97558.1 - 5.4e-26 91.0 0.2 3.5e-25 88.3 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC97558.1 - 7e-05 22.6 18.2 0.00018 21.3 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 EMC97559.1 - 1.1e-57 195.2 0.0 1.5e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Tox-GHH PF15636.1 EMC97559.1 - 0.082 12.5 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin His_Phos_2 PF00328.17 EMC97560.1 - 1.8e-22 80.1 0.0 2.2e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HEAT PF02985.17 EMC97562.1 - 1.1e-08 34.4 3.0 0.097 12.8 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.20 EMC97562.1 - 5.1e-08 32.3 0.0 8.4e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97562.1 - 1e-07 31.3 0.0 1.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 EMC97562.1 - 3.4e-05 24.1 0.1 0.48 10.9 0.1 3.3 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 EMC97562.1 - 0.00025 21.2 2.2 0.012 15.8 0.1 2.7 1 1 3 4 4 4 3 HEAT repeats Kinase-like PF14531.1 EMC97562.1 - 0.00057 18.9 0.0 0.00093 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.2 EMC97562.1 - 0.074 12.8 0.0 1.3 8.8 0.0 2.6 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EMC97562.1 - 0.078 12.3 0.7 21 4.4 0.0 3.3 3 1 1 4 4 4 0 CLASP N terminal Ion_trans PF00520.26 EMC97565.1 - 3.3e-09 36.2 2.0 4.7e-09 35.7 1.4 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 EMC97565.1 - 0.029 12.8 3.6 0.04 12.3 2.4 1.3 1 1 0 1 1 1 0 Polycystin cation channel KOW PF00467.24 EMC97566.1 - 0.015 14.9 3.6 0.049 13.3 2.5 1.9 1 0 0 1 1 1 0 KOW motif Y_phosphatase2 PF03162.8 EMC97567.1 - 6.8e-41 139.3 0.0 7.4e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EMC97567.1 - 1.1e-08 35.5 0.0 2.4e-06 27.9 0.0 2.0 1 1 1 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.15 EMC97567.1 - 0.007 15.9 0.0 0.0079 15.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC97567.1 - 0.04 13.2 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ras PF00071.17 EMC97568.1 - 2.6e-55 186.2 0.0 3e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC97568.1 - 1.6e-15 57.6 0.0 2.6e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC97568.1 - 8.7e-07 28.3 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC97568.1 - 0.002 17.3 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EMC97568.1 - 0.016 14.6 0.0 3.7 7.0 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EMC97568.1 - 0.02 14.0 0.0 0.025 13.7 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DSPc PF00782.15 EMC97569.1 - 4.3e-27 94.3 0.0 5.7e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Yippee-Mis18 PF03226.9 EMC97569.1 - 0.0048 16.9 0.5 0.012 15.6 0.3 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Y_phosphatase PF00102.22 EMC97569.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC97569.1 - 0.015 15.5 0.1 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-RING_5 PF14634.1 EMC97569.1 - 0.067 12.9 5.1 0.79 9.4 3.5 2.3 1 1 0 1 1 1 0 zinc-RING finger domain PTPlike_phytase PF14566.1 EMC97569.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Terminase_GpA PF05876.7 EMC97569.1 - 0.14 10.4 4.0 0.29 9.4 2.8 1.6 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) Mu-like_Com PF10122.4 EMC97569.1 - 0.41 9.7 4.2 1.3 8.1 0.2 2.8 3 0 0 3 3 3 0 Mu-like prophage protein Com zf-C2H2 PF00096.21 EMC97569.1 - 0.65 10.4 4.7 0.38 11.2 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC97570.1 - 0.00011 22.2 22.0 0.35 11.2 1.1 4.8 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC97570.1 - 0.0011 19.1 22.2 0.012 15.8 0.6 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC97570.1 - 0.015 15.5 0.3 0.015 15.5 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-CHCC PF10276.4 EMC97570.1 - 0.057 13.2 3.7 2.6 7.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain Lyase_1 PF00206.15 EMC97571.1 - 5.9e-95 318.0 0.0 8.4e-95 317.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EMC97571.1 - 5.9e-27 93.5 0.0 1.3e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DPBB_1 PF03330.13 EMC97572.1 - 0.00032 20.6 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EMC97572.1 - 0.011 15.3 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 0 Barwin family DUF4448 PF14610.1 EMC97573.1 - 9.6e-06 25.2 0.1 1.5e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EMC97573.1 - 0.0003 20.0 7.1 0.0003 20.0 4.9 3.0 4 1 0 4 4 4 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EMC97573.1 - 0.00054 19.6 0.1 0.00081 19.1 0.1 1.2 1 0 0 1 1 1 1 Rifin/stevor family SCF PF02404.10 EMC97573.1 - 0.061 12.5 0.3 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 Stem cell factor CcmH PF03918.9 EMC97573.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein TMEM154 PF15102.1 EMC97573.1 - 0.085 12.5 12.2 1.2 8.7 8.5 2.5 1 1 0 1 1 1 0 TMEM154 protein family LRR19-TM PF15176.1 EMC97573.1 - 0.13 11.9 0.1 6.8 6.4 0.2 2.5 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF2207 PF09972.4 EMC97573.1 - 0.15 10.5 0.1 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.10 EMC97573.1 - 0.9 9.7 4.8 0.37 11.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Polysacc_deac_1 PF01522.16 EMC97574.1 - 8.9e-19 67.3 0.0 3.5e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase adh_short PF00106.20 EMC97574.1 - 1.4e-18 67.3 0.1 5.3e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97574.1 - 4e-12 46.4 0.0 9.6e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMC97574.1 - 8.7e-07 29.1 0.1 5.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EMC97574.1 - 6.4e-06 25.9 0.2 4.5e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC97574.1 - 0.00039 19.9 0.0 0.00087 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC97574.1 - 0.001 17.8 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2334 PF10096.4 EMC97574.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Aminotran_3 PF00202.16 EMC97575.1 - 3.1e-44 151.2 0.1 5.5e-44 150.3 0.1 1.3 1 1 0 1 1 1 1 Aminotransferase class-III MmgE_PrpD PF03972.9 EMC97576.1 - 5.1e-52 176.5 9.2 4.4e-39 133.9 5.4 2.0 1 1 1 2 2 2 2 MmgE/PrpD family DUF3674 PF12426.3 EMC97577.1 - 0.087 12.2 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA dependent RNA polymerase HEPPP_synt_1 PF07307.6 EMC97577.1 - 0.22 10.9 1.8 0.21 11.0 0.1 1.6 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Ribosomal_L34 PF00468.12 EMC97577.1 - 0.29 10.8 0.1 0.29 10.8 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein L34 MHYT PF03707.11 EMC97581.1 - 2.2e-05 24.4 20.6 0.00054 20.0 0.2 4.6 6 0 0 6 6 6 3 Bacterial signalling protein N terminal repeat EamA PF00892.15 EMC97582.1 - 2e-20 73.1 20.3 1.2e-10 41.4 3.1 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EMC97582.1 - 5.2e-08 33.0 21.4 0.00034 20.7 4.6 3.1 3 0 0 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 EMC97582.1 - 0.044 12.7 8.0 0.25 10.1 2.7 2.1 2 0 0 2 2 2 0 UAA transporter family Sugar_tr PF00083.19 EMC97584.1 - 4e-83 279.4 14.8 4.6e-83 279.2 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC97584.1 - 1.8e-08 33.5 23.9 2.1e-07 30.0 15.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 EMC97585.1 - 1.2e-45 156.0 0.0 1.5e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMC97585.1 - 3.9e-05 22.9 0.0 0.00022 20.5 0.0 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase Mob1_phocein PF03637.12 EMC97585.1 - 0.048 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Mob1/phocein family Sugar_tr PF00083.19 EMC97586.1 - 3.3e-96 322.6 27.5 9.7e-90 301.2 13.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC97586.1 - 7.5e-17 61.0 36.9 8.8e-17 60.8 19.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Peroxin-3 PF04882.7 EMC97587.1 - 5.7e-131 437.1 0.0 6.7e-131 436.9 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Glyco_transf_22 PF03901.12 EMC97588.1 - 1.3e-55 189.1 17.6 1.6e-55 188.7 12.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4383 PF14325.1 EMC97588.1 - 0.021 14.8 2.6 0.039 13.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Aldo_ket_red PF00248.16 EMC97591.1 - 1.2e-50 171.9 0.0 1.6e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glycos_transf_1 PF00534.15 EMC97593.1 - 9.8e-19 67.4 0.0 1.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMC97593.1 - 6.4e-10 39.2 0.0 4.7e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMC97593.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 60KD_IMP PF02096.15 EMC97594.1 - 3.7e-07 29.9 0.0 8.7e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 60Kd inner membrane protein DUF2416 PF10315.4 EMC97595.1 - 2.5e-05 24.4 0.1 3.4e-05 24.0 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DnaJ PF00226.26 EMC97596.1 - 1.3e-22 79.2 0.3 2e-22 78.6 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EMC97596.1 - 1.6e-19 70.1 0.0 2.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) ADP_ribosyl_GH PF03747.9 EMC97596.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase MAP7 PF05672.6 EMC97596.1 - 1.1 8.5 3.7 0.44 9.9 0.9 1.4 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF974 PF06159.8 EMC97597.1 - 9.1e-64 215.2 0.0 1.2e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF2408 PF10303.4 EMC97598.1 - 2.4e-46 157.1 6.2 2.2e-22 79.6 0.6 5.2 3 3 2 5 5 5 4 Protein of unknown function (DUF2408) SPX PF03105.14 EMC97598.1 - 0.018 14.8 0.3 0.036 13.8 0.2 1.6 1 0 0 1 1 1 0 SPX domain DUF3368 PF11848.3 EMC97598.1 - 0.078 12.5 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Snapin_Pallidin PF14712.1 EMC97598.1 - 1.6 9.0 6.7 0.82 10.0 0.6 3.2 4 0 0 4 4 4 0 Snapin/Pallidin Ribosomal_60s PF00428.14 EMC97599.1 - 7.2e-21 74.3 23.6 6.3e-20 71.3 16.3 1.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein Totivirus_coat PF05518.6 EMC97599.1 - 0.081 10.7 0.8 0.087 10.6 0.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein SOG2 PF10428.4 EMC97600.1 - 1.5e-52 178.7 10.3 1.5e-52 178.7 7.2 2.1 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EMC97600.1 - 1.2e-13 50.2 5.9 3.9e-06 26.3 0.1 3.5 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC97600.1 - 2.4e-12 46.4 6.9 2.4e-06 27.2 0.3 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EMC97600.1 - 6e-08 31.6 3.2 0.038 14.0 0.1 5.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 EMC97600.1 - 1.3e-06 27.5 0.9 1.2 9.6 0.1 5.3 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EMC97600.1 - 0.026 14.5 0.6 39 4.7 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat BPL_LplA_LipB PF03099.14 EMC97601.1 - 7.9e-12 45.2 0.0 3.1e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2217 PF10265.4 EMC97602.1 - 0.17 10.6 2.7 0.27 9.9 1.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Mur_ligase_M PF08245.7 EMC97603.1 - 0.0013 18.8 0.0 0.0073 16.3 0.0 2.1 2 0 0 2 2 2 1 Mur ligase middle domain Lactonase PF10282.4 EMC97605.1 - 1.7e-05 24.0 0.1 0.99 8.4 0.0 3.7 3 1 1 4 4 4 3 Lactonase, 7-bladed beta-propeller Metallophos_2 PF12850.2 EMC97606.1 - 4.1e-12 46.2 0.0 5.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.14 EMC97607.1 - 7.2e-30 103.9 0.0 9e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMC97607.1 - 4.3e-05 21.9 0.0 6.9e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 EMC97607.1 - 0.0015 18.3 0.0 0.0049 16.7 0.0 1.8 2 0 0 2 2 2 1 B12 binding domain ILVD_EDD PF00920.16 EMC97608.1 - 3.9e-152 507.3 0.5 4.5e-152 507.1 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family DAO PF01266.19 EMC97609.1 - 0.0071 15.2 0.1 0.0082 15.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMC97609.1 - 0.028 13.4 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_3 PF07859.8 EMC97610.1 - 4.8e-47 160.2 0.0 7.6e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3025 PF11227.3 EMC97610.1 - 5e-05 22.8 0.0 9.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3025) COesterase PF00135.23 EMC97610.1 - 0.0012 17.6 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydro_lipase PF04083.11 EMC97610.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Esterase_phd PF10503.4 EMC97610.1 - 0.063 12.5 1.0 0.34 10.1 0.2 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase Elong-fact-P_C PF09285.6 EMC97611.1 - 0.02 14.2 0.0 0.063 12.6 0.0 1.9 2 0 0 2 2 2 0 Elongation factor P, C-terminal ABC2_membrane PF01061.19 EMC97612.1 - 3.7e-22 78.5 18.8 6e-22 77.8 13.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMC97612.1 - 1.1e-11 45.1 0.0 1.8e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.12 EMC97612.1 - 5.7e-05 22.6 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF258 PF03193.11 EMC97612.1 - 0.00024 20.3 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMC97612.1 - 0.00033 20.1 0.1 0.00079 18.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMC97612.1 - 0.00057 19.9 0.0 0.00094 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EMC97612.1 - 0.0013 18.4 0.3 0.0037 16.9 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 EMC97612.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC97612.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC97612.1 - 0.002 18.9 0.0 0.013 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EMC97612.1 - 0.0053 17.0 0.0 0.0089 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMC97612.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 EMC97612.1 - 0.0082 15.6 0.1 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EMC97612.1 - 0.009 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_28 PF13521.1 EMC97612.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EMC97612.1 - 0.016 15.2 0.1 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMC97612.1 - 0.027 14.0 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EMC97612.1 - 0.033 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PDR_assoc PF08370.6 EMC97612.1 - 0.034 13.6 0.3 0.14 11.6 0.2 2.1 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_33 PF13671.1 EMC97612.1 - 0.043 13.6 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMC97612.1 - 0.046 13.3 0.1 0.14 11.7 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EMC97612.1 - 0.052 13.2 0.2 0.1 12.2 0.0 1.6 2 0 0 2 2 1 0 NACHT domain SRP54 PF00448.17 EMC97612.1 - 0.052 12.9 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EMC97612.1 - 0.069 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 EMC97612.1 - 0.075 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Dynamin_N PF00350.18 EMC97612.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Dynamin family NB-ARC PF00931.17 EMC97612.1 - 0.091 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.4 EMC97612.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EMC97612.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMC97612.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EMC97612.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EMC97612.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EMC97612.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EMC97612.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Fungal_trans PF04082.13 EMC97613.1 - 8.2e-32 110.0 0.0 1.3e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC97613.1 - 4.6e-07 29.6 7.9 4.6e-07 29.6 5.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF632 PF04782.7 EMC97613.1 - 0.11 11.6 0.2 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) GSK-3_bind PF05350.7 EMC97613.1 - 1 8.7 5.5 1.7 7.9 3.8 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Methyltransf_3 PF01596.12 EMC97614.1 - 3.2e-29 101.4 0.0 3.6e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMC97614.1 - 1.3e-11 45.3 0.0 1.7e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC97614.1 - 4.8e-09 35.9 0.0 6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC97614.1 - 8.6e-09 35.9 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC97614.1 - 6e-06 26.2 0.0 8.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC97614.1 - 1.5e-05 24.1 0.0 2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EMC97614.1 - 0.00024 20.6 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EMC97614.1 - 0.0026 17.1 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 EMC97614.1 - 0.0086 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EMC97614.1 - 0.023 14.2 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.7 EMC97614.1 - 0.11 13.0 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EMC97614.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G DENN PF02141.16 EMC97616.1 - 2.7e-54 183.7 0.5 4.4e-54 183.0 0.3 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EMC97616.1 - 1.9e-19 69.3 0.0 4.1e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EMC97616.1 - 7.1e-17 61.2 2.9 1.9e-16 59.8 2.0 1.7 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.17 EMC97616.1 - 0.031 13.9 8.9 0.052 13.2 6.2 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 EMC97616.1 - 0.13 12.4 9.2 0.28 11.3 6.4 1.6 1 0 0 1 1 1 0 C1 domain SPA PF08616.5 EMC97616.1 - 0.18 11.5 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.24 EMC97616.1 - 3.5 7.3 8.9 8.6 6.1 6.2 1.7 1 0 0 1 1 1 0 PHD-finger CRAL_TRIO_2 PF13716.1 EMC97617.1 - 9e-31 106.7 0.0 1.4e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EMC97617.1 - 6.3e-19 68.0 0.0 1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EMC97617.1 - 0.0037 16.7 0.0 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain DUF1708 PF08101.6 EMC97617.1 - 0.26 10.0 0.0 0.42 9.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Asn_synthase PF00733.16 EMC97618.1 - 1.2e-66 224.8 0.0 1.7e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMC97618.1 - 1.9e-38 130.9 0.0 3.5e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMC97618.1 - 2.6e-29 101.8 0.0 4.8e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EMC97618.1 - 1.5e-07 30.8 0.0 2.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EMC97618.1 - 1.5e-05 23.8 0.0 0.00014 20.7 0.0 2.1 1 1 1 2 2 2 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EMC97618.1 - 0.028 13.3 0.0 0.055 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD synthase Porin_3 PF01459.17 EMC97619.1 - 1.4e-48 165.6 3.5 1.6e-48 165.4 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Chorismate_synt PF01264.16 EMC97620.1 - 3.4e-126 420.3 0.0 4.1e-126 420.1 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 EMC97620.1 - 5.9 6.8 5.6 19 5.2 1.0 2.8 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Methyltransf_23 PF13489.1 EMC97623.1 - 1.7e-17 63.6 0.1 1.5e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC97623.1 - 1.2e-15 57.7 0.0 2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC97623.1 - 9.3e-14 51.2 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMC97623.1 - 1.7e-12 46.9 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EMC97623.1 - 3.8e-11 43.5 0.0 6.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC97623.1 - 2.3e-10 40.7 0.0 3.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC97623.1 - 3e-10 40.1 0.0 1e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC97623.1 - 3.8e-08 33.6 0.0 6.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC97623.1 - 3.3e-06 26.3 0.0 6.7e-05 22.1 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMC97623.1 - 3.9e-05 23.0 0.0 7.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EMC97623.1 - 4.6e-05 23.0 0.0 9.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EMC97623.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.6 EMC97623.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.1 EMC97623.1 - 0.0028 18.4 0.1 0.0061 17.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EMC97623.1 - 0.0045 16.1 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.11 EMC97623.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_9 PF08003.6 EMC97623.1 - 0.031 12.9 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_20 PF12147.3 EMC97623.1 - 0.042 12.7 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.5 EMC97623.1 - 0.087 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DREV PF05219.7 EMC97623.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FAD_binding_4 PF01565.18 EMC97624.1 - 2.1e-20 72.6 0.0 3.4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Alg14 PF08660.6 EMC97625.1 - 1.3e-49 168.4 0.0 6.4e-49 166.2 0.0 1.9 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like IF-2B PF01008.12 EMC97626.1 - 1.4e-54 185.0 2.0 3.2e-32 111.6 0.0 2.9 2 1 0 2 2 2 2 Initiation factor 2 subunit family DUF2493 PF10686.4 EMC97626.1 - 0.0033 16.9 0.5 0.28 10.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2493) Polysacc_deac_1 PF01522.16 EMC97627.1 - 9.9e-22 76.8 0.0 3.1e-21 75.2 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.4 EMC97627.1 - 2.2e-06 27.2 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.10 EMC97627.1 - 0.067 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF2194 PF09960.4 EMC97627.1 - 0.072 11.1 0.3 0.15 10.1 0.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF771 PF05595.6 EMC97627.1 - 0.093 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF771) AAT PF03417.11 EMC97628.1 - 2.2e-33 115.6 0.0 2.7e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EMC97628.1 - 3.7e-05 23.9 0.0 7.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4407 PF14362.1 EMC97629.1 - 0.0005 19.1 3.4 0.001 18.0 2.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) bZIP_2 PF07716.10 EMC97629.1 - 0.0015 18.2 0.3 0.0043 16.8 0.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper CEP19 PF14933.1 EMC97629.1 - 0.014 15.7 0.4 0.025 14.8 0.3 1.5 1 0 0 1 1 1 0 CEP19-like protein IncA PF04156.9 EMC97629.1 - 0.023 14.2 2.7 0.043 13.4 1.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EMC97629.1 - 0.073 13.5 9.2 0.32 11.4 0.5 3.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) YlqD PF11068.3 EMC97629.1 - 0.13 12.2 5.2 0.3 11.1 3.6 1.6 1 0 0 1 1 1 0 YlqD protein DUF3708 PF12501.3 EMC97629.1 - 0.16 11.7 0.3 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter V_ATPase_I PF01496.14 EMC97629.1 - 0.24 9.2 1.6 0.36 8.6 1.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 EMC97629.1 - 0.38 10.6 11.3 0.76 9.7 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4618 PF15397.1 EMC97629.1 - 0.43 9.8 8.8 2 7.6 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) OEP PF02321.13 EMC97629.1 - 1 8.8 7.4 3.2 7.2 5.1 1.7 1 1 0 1 1 1 0 Outer membrane efflux protein Cnl2_NKP2 PF09447.5 EMC97629.1 - 1.1 8.9 4.8 1.3 8.7 1.1 2.7 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Glutaredoxin PF00462.19 EMC97630.1 - 1.3e-15 57.1 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin APC_crr PF05923.7 EMC97630.1 - 0.057 13.0 0.1 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 APC cysteine-rich region Flavoprotein PF02441.14 EMC97631.1 - 7.1e-40 135.6 0.1 1.5e-39 134.6 0.0 1.5 2 0 0 2 2 2 1 Flavoprotein CD20 PF04103.10 EMC97632.1 - 0.15 11.9 15.3 0.37 10.7 3.6 3.3 2 2 1 3 3 3 0 CD20-like family DUF2627 PF11118.3 EMC97632.1 - 0.38 10.8 6.8 0.3 11.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) TM140 PF14985.1 EMC97632.1 - 0.44 10.1 7.1 0.13 11.9 0.5 2.3 2 1 0 3 3 3 0 TM140 protein family Claudin_2 PF13903.1 EMC97632.1 - 6.4 6.4 12.9 4.3 7.0 0.5 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Glyco_hydro_10 PF00331.15 EMC97633.1 - 8.2e-74 248.4 2.1 1e-73 248.1 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 4F5 PF04419.9 EMC97634.1 - 1.8e-10 41.3 13.6 1.8e-10 41.3 9.4 1.5 2 0 0 2 2 2 1 4F5 protein family Phage_Gp23 PF10669.4 EMC97634.1 - 0.49 10.5 2.9 0.52 10.4 2.0 1.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Motile_Sperm PF00635.21 EMC97635.1 - 1.2e-25 89.2 0.0 2.5e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Selenoprotein_S PF06936.6 EMC97635.1 - 0.0031 17.0 0.1 0.0055 16.2 0.1 1.3 1 0 0 1 1 1 1 Selenoprotein S (SelS) Baculo_PEP_C PF04513.7 EMC97635.1 - 0.034 13.9 3.6 0.063 13.1 2.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2130 PF09903.4 EMC97635.1 - 0.12 11.0 1.0 0.18 10.5 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) MRP-S31 PF15433.1 EMC97635.1 - 0.21 10.9 1.4 0.32 10.3 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 UBX PF00789.15 EMC97636.1 - 2e-05 24.5 0.0 6.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 EMC97636.1 - 0.00014 21.5 0.0 0.00051 19.8 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain CAF-1_p150 PF11600.3 EMC97636.1 - 0.015 14.6 37.3 0.024 14.0 25.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UBA_3 PF09288.5 EMC97636.1 - 0.016 14.8 0.4 0.97 9.0 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain SOBP PF15279.1 EMC97636.1 - 0.053 13.9 6.9 0.062 13.6 4.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 EMC97636.1 - 0.36 8.5 9.6 0.38 8.4 6.7 1.2 1 0 0 1 1 1 0 Ycf1 APG6 PF04111.7 EMC97636.1 - 1.2 8.1 21.2 1.8 7.5 14.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF572 PF04502.8 EMC97636.1 - 1.8 7.6 33.6 1.1 8.4 22.2 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) PLRV_ORF5 PF01690.12 EMC97636.1 - 3.3 6.7 16.6 3.9 6.5 11.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DAO PF01266.19 EMC97637.1 - 9.9e-51 172.7 0.0 1.7e-50 171.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC97637.1 - 2.6e-09 36.4 0.3 6.2e-09 35.2 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMC97637.1 - 1.2e-08 34.5 0.0 3.6e-06 26.3 0.0 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC97637.1 - 8e-05 22.6 0.0 0.00041 20.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMC97637.1 - 0.00042 20.0 0.1 0.00095 18.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EMC97637.1 - 0.0025 16.7 0.1 0.013 14.3 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EMC97637.1 - 0.0092 14.4 0.4 0.017 13.5 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EMC97637.1 - 0.01 15.8 0.2 0.037 14.0 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC97637.1 - 0.023 15.0 0.1 0.11 12.8 0.1 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC97637.1 - 0.034 13.0 0.6 0.081 11.8 0.3 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.13 EMC97637.1 - 0.047 12.0 0.1 0.36 9.0 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox_3 PF13738.1 EMC97637.1 - 0.075 13.0 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FANCI_HD1 PF14679.1 EMC97638.1 - 0.025 14.3 0.0 0.029 14.0 0.0 1.0 1 0 0 1 1 1 0 FANCI helical domain 1 zf-H2C2_2 PF13465.1 EMC97639.1 - 2.6e-14 52.6 7.4 5.7e-08 32.6 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC97639.1 - 4.9e-12 45.4 11.8 1.4e-05 25.1 1.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC97639.1 - 6.1e-11 41.8 11.7 4.1e-05 23.6 1.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC97639.1 - 1.1e-06 28.6 2.4 0.094 12.8 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC97639.1 - 3.6e-05 23.8 1.6 0.011 15.8 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EMC97639.1 - 0.27 11.5 2.2 0.18 12.0 0.3 1.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain LIM PF00412.17 EMC97639.1 - 1.5 8.9 4.1 10 6.3 2.8 2.1 1 1 1 2 2 2 0 LIM domain zf-BED PF02892.10 EMC97639.1 - 2.4 7.9 4.5 6.8 6.5 0.8 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EMC97639.1 - 3.8 7.5 8.2 24 4.9 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger FMN_dh PF01070.13 EMC97640.1 - 3.4e-105 351.8 0.0 4.2e-105 351.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMC97640.1 - 2.4e-05 23.4 0.3 3.5e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMC97640.1 - 0.00029 20.0 0.2 0.00048 19.3 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EMC97640.1 - 0.0014 17.9 0.3 0.092 11.9 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.12 EMC97640.1 - 0.0034 16.3 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EMC97640.1 - 0.016 14.3 0.2 0.87 8.6 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG XPG_I_2 PF12813.2 EMC97641.1 - 0.012 15.1 0.2 0.013 14.9 0.1 1.1 1 0 0 1 1 1 0 XPG domain containing Glyco_transf_22 PF03901.12 EMC97642.1 - 7.2e-82 275.6 4.0 9.8e-82 275.1 2.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2645 PF10840.3 EMC97642.1 - 0.00089 19.3 0.1 0.0033 17.5 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2645) DUF2029 PF09594.5 EMC97643.1 - 0.0028 17.1 1.0 0.0057 16.1 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) TrbC PF04956.8 EMC97643.1 - 0.0073 16.3 0.9 0.022 14.7 0.1 2.2 2 0 0 2 2 2 1 TrbC/VIRB2 family DUF533 PF04391.7 EMC97643.1 - 0.087 12.1 0.2 0.087 12.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF533) Mitofilin PF09731.4 EMC97643.1 - 0.46 9.0 16.7 0.59 8.7 11.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.8 EMC97643.1 - 1.4 8.7 26.1 2.1 8.1 18.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EMC97643.1 - 4.4 6.6 39.3 7 5.9 27.3 1.3 1 0 0 1 1 1 0 Vta1 like FAM196 PF15265.1 EMC97643.1 - 7.3 5.7 31.2 9.9 5.2 21.7 1.2 1 0 0 1 1 1 0 FAM196 family AAA PF00004.24 EMC97645.1 - 3.4e-15 56.4 0.0 6.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC97645.1 - 0.00012 22.1 1.1 0.056 13.5 0.8 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC97645.1 - 0.007 16.3 0.1 0.029 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EMC97645.1 - 0.012 15.3 0.0 0.049 13.3 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 EMC97645.1 - 0.11 13.2 0.3 0.69 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 EMC97645.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_5 PF07728.9 EMC97645.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EMC97645.1 - 0.5 9.4 2.0 1.7 7.7 0.4 2.3 2 1 1 3 3 3 0 KaiC DASH_Dad2 PF08654.5 EMC97646.1 - 1.1e-26 92.8 2.1 1.3e-26 92.5 1.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 HAUS2 PF15003.1 EMC97646.1 - 0.0008 18.5 0.0 0.0008 18.5 0.0 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Seryl_tRNA_N PF02403.17 EMC97646.1 - 0.013 15.4 0.6 0.018 15.0 0.4 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DASH_Duo1 PF08651.5 EMC97646.1 - 0.016 14.7 0.2 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 GCN5L1 PF06320.8 EMC97646.1 - 0.024 14.4 0.8 0.073 12.9 0.6 1.6 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) IFT20 PF14931.1 EMC97646.1 - 0.046 13.6 1.8 0.087 12.7 1.3 1.5 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Peptidase_S64 PF08192.6 EMC97646.1 - 0.051 11.9 0.2 0.049 11.9 0.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 NPV_P10 PF05531.7 EMC97646.1 - 0.059 13.6 1.2 0.083 13.1 0.8 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 EMC97646.1 - 0.2 11.6 5.8 2.6 8.0 0.3 2.0 1 1 1 2 2 2 0 FlxA-like protein Shugoshin_N PF07558.6 EMC97647.1 - 8.5e-12 44.5 4.0 1.9e-11 43.4 2.8 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EMC97647.1 - 1.4e-10 40.4 5.1 1.4e-10 40.4 3.5 2.7 3 0 0 3 3 3 1 Shugoshin C terminus CASP_C PF08172.7 EMC97647.1 - 0.83 8.6 5.4 0.28 10.1 1.4 1.9 2 0 0 2 2 2 0 CASP C terminal CRM1_C PF08767.6 EMC97648.1 - 3.8e-131 436.7 4.8 4.6e-131 436.4 0.9 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.7 EMC97648.1 - 3.6e-39 134.0 9.4 3.7e-39 133.9 1.5 4.1 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EMC97648.1 - 1.8e-11 43.8 0.1 6.9e-11 41.9 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 EMC97648.1 - 0.023 14.9 2.3 14 6.0 0.1 3.8 4 0 0 4 4 4 0 Phosphohydrolase-associated domain BID PF06393.6 EMC97648.1 - 0.025 13.9 0.3 0.065 12.5 0.2 1.7 1 0 0 1 1 1 0 BH3 interacting domain (BID) YbjQ_1 PF01906.12 EMC97648.1 - 0.068 13.6 0.1 0.48 10.8 0.0 2.4 2 0 0 2 2 2 0 Putative heavy-metal-binding Vac14_Fab1_bd PF12755.2 EMC97648.1 - 2.2 8.7 5.3 13 6.2 0.0 4.4 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region PPI_Ypi1 PF07491.6 EMC97649.1 - 1e-23 82.6 0.5 1.9e-23 81.8 0.4 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.7 EMC97649.1 - 0.0062 14.9 7.7 0.0061 14.9 5.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ecl1 PF12855.2 EMC97652.1 - 8.1e-07 28.2 6.5 2.7e-06 26.5 4.5 1.9 1 1 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 EMC97652.1 - 0.021 14.3 2.1 0.021 14.3 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF329) IBR PF01485.16 EMC97652.1 - 0.33 10.8 3.1 0.8 9.6 2.1 1.7 1 0 0 1 1 1 0 IBR domain Form_Nir_trans PF01226.12 EMC97653.1 - 1.5e-76 256.6 25.7 1.8e-76 256.3 17.8 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DUF4142 PF13628.1 EMC97655.1 - 0.024 14.6 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) adh_short PF00106.20 EMC97656.1 - 9.9e-25 87.3 0.0 1.3e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97656.1 - 8.7e-24 84.6 0.0 1e-23 84.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97656.1 - 3.9e-08 33.1 0.0 5.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMC97656.1 - 0.0017 18.0 0.0 0.0049 16.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMC97656.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EMC97656.1 - 0.077 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EMP24_GP25L PF01105.19 EMC97657.1 - 1.4e-48 165.0 0.0 1.6e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FA_desaturase PF00487.19 EMC97658.1 - 4.5e-26 91.8 17.0 6.2e-26 91.3 11.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EMC97658.1 - 8.3e-20 69.7 0.0 1.3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HeLo PF14479.1 EMC97659.1 - 4.2e-27 95.2 0.2 9.9e-27 94.0 0.0 1.7 1 1 1 2 2 2 1 Prion-inhibition and propagation p450 PF00067.17 EMC97660.1 - 1.8e-28 99.2 0.0 7.1e-28 97.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 SUFU PF05076.8 EMC97660.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) Alba PF01918.16 EMC97663.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Alba NCD2 PF04905.8 EMC97663.1 - 0.047 13.4 0.0 0.066 13.0 0.0 1.3 1 1 0 1 1 1 0 NAB conserved region 2 (NCD2) Aminotran_4 PF01063.14 EMC97664.1 - 1.9e-22 79.8 0.0 3.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV GAS PF13851.1 EMC97668.1 - 0.0011 18.1 3.9 0.0011 18.1 2.7 1.5 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 EMC97668.1 - 0.0052 16.6 3.0 0.0084 15.9 2.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HALZ PF02183.13 EMC97668.1 - 0.24 11.1 5.3 2.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper V_ATPase_I PF01496.14 EMC97668.1 - 0.59 7.9 2.1 0.7 7.6 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4510 PF14971.1 EMC97668.1 - 0.76 9.9 3.3 4.3 7.4 2.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) DivIC PF04977.10 EMC97668.1 - 0.95 8.9 7.5 4.7 6.7 0.2 3.1 2 1 1 3 3 3 0 Septum formation initiator DUF1843 PF08898.5 EMC97668.1 - 1.2 9.2 3.4 4.5 7.3 0.0 3.3 4 1 0 4 4 3 0 Domain of unknown function (DUF1843) bZIP_1 PF00170.16 EMC97668.1 - 1.4 8.9 7.1 1.6 8.7 0.3 3.0 2 1 1 3 3 3 0 bZIP transcription factor DUF904 PF06005.7 EMC97668.1 - 1.7 9.0 7.8 1.1 9.5 2.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) CENP-H PF05837.7 EMC97668.1 - 2.4 8.3 7.4 0.71 10.0 2.5 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) APG6 PF04111.7 EMC97668.1 - 2.5 7.0 7.5 0.51 9.3 2.6 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.7 EMC97668.1 - 3.2 7.1 4.7 1.1 8.7 1.5 1.5 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Rho_Binding PF08912.6 EMC97668.1 - 3.7 7.9 7.5 5.7 7.3 0.1 2.9 2 1 1 3 3 3 0 Rho Binding DUF1192 PF06698.6 EMC97668.1 - 7.7 6.4 7.6 9.5 6.1 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Acetyltransf_1 PF00583.19 EMC97669.1 - 2.2e-12 46.8 0.0 4.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMC97669.1 - 1e-05 25.2 0.1 1.8e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EMC97669.1 - 0.0021 18.0 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC97669.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC97669.1 - 0.0045 17.1 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC97669.1 - 0.011 15.5 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMC97669.1 - 0.038 13.8 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TAP_C PF03943.8 EMC97670.1 - 2.6e-08 33.1 0.0 0.00013 21.2 0.0 3.4 3 0 0 3 3 3 3 TAP C-terminal domain DUF4381 PF14316.1 EMC97670.1 - 0.037 14.1 0.4 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF1242 PF06842.7 EMC97671.1 - 3.9e-16 58.2 1.1 5.6e-16 57.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF624 PF04854.9 EMC97671.1 - 0.0076 16.0 0.2 0.0076 16.0 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function, DUF624 DUF418 PF04235.7 EMC97671.1 - 0.025 14.2 0.3 0.025 14.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF418) TFIID-18kDa PF02269.11 EMC97672.1 - 4.2e-14 52.1 0.1 2.6e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EMC97672.1 - 0.056 13.6 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S MitMem_reg PF13012.1 EMC97673.1 - 1.7e-17 63.5 0.2 3.4e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EMC97673.1 - 1.1e-16 60.5 0.0 2.2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.8 EMC97673.1 - 0.002 17.6 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF1253 PF06862.7 EMC97674.1 - 1.9e-145 484.6 0.0 2.6e-145 484.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) zf-HIT PF04438.11 EMC97675.1 - 0.07 12.7 4.9 0.12 12.0 3.4 1.4 1 0 0 1 1 1 0 HIT zinc finger adh_short PF00106.20 EMC97677.1 - 1.6e-05 24.9 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97677.1 - 0.0002 21.2 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97677.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_4 PF04669.8 EMC97677.1 - 0.058 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis PRELI PF04707.9 EMC97678.1 - 1.7e-35 121.9 0.0 2e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Tcp11 PF05794.8 EMC97679.1 - 7.8e-57 192.9 0.0 1.3e-56 192.2 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 AA_kinase PF00696.23 EMC97680.1 - 5.4e-41 140.7 0.2 9.1e-41 139.9 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EMC97680.1 - 8.7e-13 47.4 0.4 1.4e-08 34.0 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EMC97680.1 - 1.5e-09 37.2 0.6 9.1e-07 28.3 0.1 2.5 2 0 0 2 2 2 2 ACT domain ADH_zinc_N_2 PF13602.1 EMC97681.1 - 1.2e-14 55.3 0.0 2.7e-14 54.1 0.0 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMC97681.1 - 5.9e-06 25.8 2.6 0.0001 21.8 1.8 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC97681.1 - 0.028 14.1 1.2 6.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain DUF1582 PF07621.6 EMC97682.1 - 0.081 12.9 0.6 0.27 11.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) GHMP_kinases_N PF00288.21 EMC97685.1 - 1.2e-11 44.4 0.7 3.7e-11 42.9 0.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMC97685.1 - 0.04 14.1 0.1 1 9.5 0.0 2.9 4 0 0 4 4 4 0 GHMP kinases C terminal Cyto_heme_lyase PF01265.12 EMC97686.1 - 1.4e-82 277.1 0.5 1.6e-82 276.9 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DAO PF01266.19 EMC97688.1 - 8.3e-37 126.9 0.2 1.1e-36 126.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC97688.1 - 5.3e-07 29.9 0.3 0.021 14.8 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC97688.1 - 4.2e-06 26.6 0.3 0.0056 16.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMC97688.1 - 6.2e-05 22.9 0.1 0.0002 21.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC97688.1 - 0.00033 19.6 2.2 0.0018 17.2 1.5 2.0 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMC97688.1 - 0.00074 18.0 0.0 0.07 11.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 EMC97688.1 - 0.0053 17.1 0.1 6.2 7.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC97688.1 - 0.0082 15.2 0.0 0.019 14.0 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMC97688.1 - 0.014 15.2 1.2 0.17 11.7 0.8 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC97688.1 - 0.018 14.0 0.1 0.078 11.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein SUV3_C PF12513.3 EMC97688.1 - 0.099 12.1 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal GIDA PF01134.17 EMC97688.1 - 0.18 10.6 1.3 0.58 8.9 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A MIP PF00230.15 EMC97689.1 - 1.3e-27 96.7 11.5 1.7e-27 96.3 7.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein TatD_DNase PF01026.16 EMC97690.1 - 6.5e-51 172.9 0.0 8.2e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase GYF PF02213.11 EMC97691.1 - 2.2e-12 46.3 0.1 5.2e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 GYF domain Secretin_N_2 PF07655.8 EMC97691.1 - 0.47 10.8 4.0 0.46 10.8 0.2 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Brix PF04427.13 EMC97692.1 - 1.3e-36 126.0 0.0 1.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Atg14 PF10186.4 EMC97692.1 - 1.8 7.4 8.7 2.6 6.9 6.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 tRNA-synt_2b PF00587.20 EMC97695.1 - 1.9e-60 203.3 0.1 3.2e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC97695.1 - 2.5e-19 68.9 0.3 8.2e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain CBFD_NFYB_HMF PF00808.18 EMC97696.1 - 1.9e-19 69.4 0.6 2.7e-19 68.9 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC97696.1 - 3.6e-11 43.0 0.1 5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EMC97696.1 - 0.029 14.1 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TRAPP PF04051.11 EMC97697.1 - 1.4e-40 138.2 0.0 1.7e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Tat PF00539.13 EMC97698.1 - 0.0072 15.9 0.7 0.011 15.3 0.5 1.3 1 0 0 1 1 1 1 Transactivating regulatory protein (Tat) R3H PF01424.17 EMC97699.1 - 2e-12 46.6 0.0 4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EMC97699.1 - 4.6e-08 32.9 0.0 7.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC97699.1 - 1.8e-07 30.7 0.0 3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC97699.1 - 0.068 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Atg14 PF10186.4 EMC97700.1 - 0.013 14.4 3.9 0.022 13.6 2.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 EMC97700.1 - 0.016 14.3 12.1 0.026 13.6 8.4 1.3 1 0 0 1 1 1 0 Tropomyosin Spc7 PF08317.6 EMC97700.1 - 0.037 12.7 4.1 0.059 12.0 2.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GTSE1_N PF15259.1 EMC97700.1 - 0.059 13.3 6.1 0.24 11.3 4.4 1.9 1 1 1 2 2 2 0 G-2 and S-phase expressed 1 IncA PF04156.9 EMC97700.1 - 0.066 12.8 10.9 0.13 11.8 7.6 1.4 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EMC97700.1 - 0.2 11.6 9.6 0.2 11.6 4.8 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Filament PF00038.16 EMC97700.1 - 0.21 11.0 13.7 0.21 11.0 7.9 1.8 2 0 0 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 EMC97700.1 - 0.28 9.5 2.8 0.37 9.1 1.9 1.1 1 0 0 1 1 1 0 AAA domain Sec34 PF04136.10 EMC97700.1 - 0.31 10.7 3.3 0.5 10.0 2.3 1.3 1 0 0 1 1 1 0 Sec34-like family Mnd1 PF03962.10 EMC97700.1 - 1 9.0 8.5 2 8.0 5.9 1.4 1 0 0 1 1 1 0 Mnd1 family Sec3_C_2 PF15278.1 EMC97700.1 - 1.4 9.0 4.5 13 5.9 0.4 3.0 2 1 1 3 3 3 0 Sec3 exocyst complex subunit FlaC_arch PF05377.6 EMC97700.1 - 1.6 8.6 3.8 20 5.1 0.0 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) OmpH PF03938.9 EMC97700.1 - 1.7 8.5 11.9 3 7.7 8.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2570 PF10828.3 EMC97700.1 - 4.9 6.8 10.9 6.5 6.4 4.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) DUF904 PF06005.7 EMC97700.1 - 9.6 6.5 13.3 7.1 7.0 3.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF904) TPR_11 PF13414.1 EMC97701.1 - 1e-10 41.0 0.2 1.4e-07 31.0 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC97701.1 - 2.6e-07 30.0 1.5 0.0025 17.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC97701.1 - 2.2e-05 23.8 0.0 0.34 10.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC97701.1 - 0.0005 19.9 0.1 2.5 8.1 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC97701.1 - 0.00096 18.9 0.2 0.0027 17.5 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC97701.1 - 0.0098 16.5 1.0 5.4 7.8 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC97701.1 - 0.11 13.0 0.1 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC97701.1 - 0.13 12.0 0.0 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MARVEL PF01284.18 EMC97702.1 - 7.6e-07 29.0 12.2 1.1e-06 28.5 8.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain Opacity PF02462.10 EMC97702.1 - 0.036 13.9 0.1 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Opacity family porin protein DUF89 PF01937.14 EMC97703.1 - 7.6e-131 436.1 0.0 8.7e-131 435.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF1996 PF09362.5 EMC97704.1 - 1.1e-48 166.0 0.2 2.4e-48 164.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EMC97704.1 - 1.2e-43 146.8 42.3 4.9e-15 55.2 7.6 3.6 3 0 0 3 3 3 3 WSC domain OmpH PF03938.9 EMC97705.1 - 0.034 14.0 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sugarporin_N PF11471.3 EMC97705.1 - 0.065 12.8 9.7 0.2 11.3 0.6 3.3 1 1 2 3 3 3 0 Maltoporin periplasmic N-terminal extension IncA PF04156.9 EMC97705.1 - 0.22 11.1 2.2 0.58 9.7 1.6 1.6 1 1 0 1 1 1 0 IncA protein Myb_DNA-binding PF00249.26 EMC97706.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TT_ORF2 PF02957.10 EMC97706.1 - 0.26 11.9 3.5 0.36 11.5 2.4 1.2 1 0 0 1 1 1 0 TT viral ORF2 DTHCT PF08070.6 EMC97706.1 - 1.5 9.5 10.1 2.7 8.6 6.9 1.5 1 1 0 1 1 1 0 DTHCT (NUC029) region CMAS PF02353.15 EMC97707.1 - 4.8e-35 120.9 0.8 8.1e-35 120.2 0.5 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EMC97707.1 - 3.5e-13 49.4 0.0 4.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC97707.1 - 2.1e-12 47.0 0.0 3.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC97707.1 - 2.2e-11 44.0 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC97707.1 - 7.4e-11 42.4 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC97707.1 - 3.1e-10 40.6 0.0 5.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC97707.1 - 8.6e-07 28.4 0.0 1.7e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMC97707.1 - 1.1e-05 25.7 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC97707.1 - 0.00089 18.3 0.0 0.0018 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EMC97707.1 - 0.00097 18.7 0.0 0.0045 16.5 0.0 2.0 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EMC97707.1 - 0.0014 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.15 EMC97707.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 EMC97707.1 - 0.014 14.0 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TehB PF03848.9 EMC97707.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB GidB PF02527.10 EMC97707.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G P5-ATPase PF12409.3 EMC97708.1 - 1.3e-35 121.8 1.3 3.9e-35 120.2 0.0 2.4 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 EMC97708.1 - 8.1e-32 110.9 0.0 3.4e-31 108.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMC97708.1 - 6.3e-26 90.8 0.1 4e-25 88.2 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EMC97708.1 - 5.6e-17 62.8 0.0 2.1e-12 47.9 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMC97708.1 - 4.8e-05 22.7 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMC97708.1 - 0.00069 19.2 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC97708.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit TPR_1 PF00515.23 EMC97709.1 - 2.7e-07 29.9 3.5 0.18 11.4 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC97709.1 - 6.2e-06 26.3 24.9 0.67 10.7 0.1 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC97709.1 - 1.9e-05 24.1 1.2 0.0034 17.0 0.0 4.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC97709.1 - 0.00045 20.5 18.5 0.086 13.1 0.0 5.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC97709.1 - 0.00049 20.0 2.7 0.43 10.8 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC97709.1 - 0.00054 19.8 18.7 0.18 11.7 0.1 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC97709.1 - 0.0021 17.6 19.8 0.054 13.1 1.9 6.1 6 1 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 EMC97709.1 - 0.0066 16.2 20.9 0.17 11.8 0.2 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc5 PF12862.2 EMC97709.1 - 0.48 10.3 4.7 3.7 7.4 0.0 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 RIX1 PF08167.7 EMC97710.1 - 1.4e-43 148.3 1.7 4.6e-43 146.7 1.2 1.9 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Pkinase PF00069.20 EMC97712.1 - 9.8e-65 218.2 0.0 1.3e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97712.1 - 1.6e-28 99.5 0.0 2.5e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC97712.1 - 0.23 10.3 0.0 0.99 8.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like rRNA_proc-arch PF13234.1 EMC97713.1 - 1.2e-90 303.3 0.0 3.1e-90 301.9 0.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EMC97713.1 - 1e-64 217.0 2.9 1e-64 217.0 2.0 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EMC97713.1 - 5.2e-22 78.1 0.0 1.7e-21 76.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC97713.1 - 2.1e-07 30.6 0.0 4.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC97713.1 - 0.0024 17.7 0.0 0.021 14.6 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Transferase PF02458.10 EMC97713.1 - 0.03 12.7 0.5 0.085 11.2 0.0 1.8 2 0 0 2 2 2 0 Transferase family T2SE PF00437.15 EMC97713.1 - 0.032 13.1 0.0 0.068 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4600 PF15372.1 EMC97713.1 - 5.8 7.1 10.6 8.1 6.6 1.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) DUF2921 PF11145.3 EMC97716.1 - 0.095 10.4 0.7 0.11 10.1 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) ABC1 PF03109.11 EMC97717.1 - 1.2e-30 105.9 0.0 1.9e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EMC97717.1 - 0.16 11.2 0.0 0.4 10.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family UQ_con PF00179.21 EMC97718.1 - 4.6e-47 158.9 0.0 5.2e-47 158.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC97718.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EMC97718.1 - 0.12 12.2 0.4 0.14 12.0 0.3 1.5 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 EMC97719.1 - 9.4e-62 208.8 8.5 1.4e-61 208.3 5.9 1.3 1 1 0 1 1 1 1 Pex19 protein family DUF1631 PF07793.6 EMC97719.1 - 0.045 11.8 1.8 0.067 11.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) FliE PF02049.13 EMC97719.1 - 0.052 13.5 4.7 0.17 11.9 0.7 3.0 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE GET2 PF08690.5 EMC97719.1 - 0.21 10.7 1.9 0.26 10.4 1.2 1.3 1 1 0 1 1 1 0 GET complex subunit GET2 DUF1797 PF08796.5 EMC97720.1 - 0.062 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) PPR_2 PF13041.1 EMC97721.1 - 2.3e-21 75.4 0.0 4.5e-11 42.5 0.0 3.5 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EMC97721.1 - 3.5e-13 48.6 3.3 0.00033 20.7 0.0 6.1 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 EMC97721.1 - 5.7e-11 41.6 0.0 0.00018 21.2 0.0 4.1 3 0 0 3 3 3 3 PPR repeat PPR_1 PF12854.2 EMC97721.1 - 1.9e-09 36.8 0.0 0.0057 16.0 0.0 3.8 3 0 0 3 3 3 2 PPR repeat PMBR PF09373.5 EMC97721.1 - 0.087 12.8 0.0 0.35 10.8 0.0 2.1 1 0 0 1 1 1 0 Pseudomurein-binding repeat cwf18 PF08315.7 EMC97722.1 - 4e-41 140.4 9.3 1.1e-40 139.0 5.5 2.1 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Pkinase PF00069.20 EMC97724.1 - 2.8e-49 167.5 0.0 4.1e-34 117.8 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC97724.1 - 1.5e-22 79.9 0.0 3.7e-20 72.1 0.0 3.5 3 1 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC97724.1 - 3.8e-05 22.7 0.0 0.00011 21.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RGS PF00615.14 EMC97725.1 - 1.1e-10 41.6 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain SAP PF02037.22 EMC97726.1 - 3.4e-07 29.6 0.2 6.2e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 SAP domain DUF3984 PF13136.1 EMC97727.1 - 2.3e-33 115.8 21.6 3.5e-32 111.9 15.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) p450 PF00067.17 EMC97728.1 - 1.1e-60 205.5 0.0 1.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cut8_C PF08559.5 EMC97729.1 - 1.6e-41 141.4 0.0 2.7e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EMC97729.1 - 6.3e-13 48.2 3.1 1.2e-12 47.3 2.1 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EMC97729.1 - 0.013 15.4 3.4 0.025 14.5 2.3 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain DIE2_ALG10 PF04922.7 EMC97731.1 - 1.6e-81 274.3 3.7 1.4e-80 271.2 2.5 2.0 1 1 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.6 EMC97732.1 - 1.2e-25 89.9 0.0 1.5e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L3 PF00297.17 EMC97733.1 - 1.2e-35 123.2 3.8 2.4e-35 122.1 1.3 1.8 1 1 1 2 2 2 1 Ribosomal protein L3 Hexapep PF00132.19 EMC97736.1 - 9.8e-12 43.8 12.2 3.1e-08 32.7 2.2 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.13 EMC97736.1 - 6.6e-09 35.5 11.2 1.4e-08 34.5 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 EMC97736.1 - 4.7e-07 29.2 15.9 0.00019 20.9 4.7 2.7 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EMC97736.1 - 2.3e-05 24.3 0.1 6.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Maltose acetyltransferase EamA PF00892.15 EMC97737.1 - 1.7e-10 41.0 37.4 2e-07 31.0 4.0 3.4 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EMC97737.1 - 2.9e-06 26.5 8.8 1.3e-05 24.4 5.7 2.2 2 1 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 EMC97737.1 - 4.8e-06 26.7 1.4 4.8e-06 26.7 1.0 3.1 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Mpp10 PF04006.7 EMC97738.1 - 2.6e-85 287.0 33.4 1.3e-84 284.6 23.1 1.8 1 1 0 1 1 1 1 Mpp10 protein bZIP_2 PF07716.10 EMC97739.1 - 9.1e-12 44.6 12.2 9.1e-12 44.6 8.4 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC97739.1 - 0.00017 21.4 11.6 0.00017 21.4 8.0 1.9 2 1 0 2 2 2 1 bZIP transcription factor Transposase_22 PF02994.9 EMC97739.1 - 0.0061 15.1 0.2 0.0084 14.6 0.1 1.2 1 0 0 1 1 1 1 L1 transposable element DUF904 PF06005.7 EMC97739.1 - 0.037 14.3 2.2 0.1 12.9 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF3395 PF11875.3 EMC97739.1 - 0.097 12.3 4.3 0.17 11.4 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) XhlA PF10779.4 EMC97739.1 - 0.2 11.5 1.9 0.41 10.5 1.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA DUF2762 PF10960.3 EMC97739.1 - 0.22 11.2 2.1 0.39 10.4 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) CASP_C PF08172.7 EMC97739.1 - 0.3 10.0 4.4 0.54 9.2 3.1 1.6 1 1 0 1 1 1 0 CASP C terminal DUF972 PF06156.8 EMC97739.1 - 0.97 9.8 4.3 1.2 9.5 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) 2OG-FeII_Oxy PF03171.15 EMC97740.1 - 5e-05 23.5 0.0 9.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMC97740.1 - 0.00089 19.7 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_7 PF00840.15 EMC97745.1 - 2e-142 474.6 17.0 2.4e-142 474.3 11.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 WD40 PF00400.27 EMC97746.1 - 1.9e-18 65.5 14.0 2e-08 33.8 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMC97746.1 - 1.7e-16 59.8 0.0 3.5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Lactonase PF10282.4 EMC97746.1 - 0.056 12.5 0.1 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ATP_bind_3 PF01171.15 EMC97747.1 - 5.7e-18 65.0 0.0 1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 EMC97747.1 - 0.0022 17.3 0.6 0.0022 17.3 0.4 2.5 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.11 EMC97747.1 - 0.047 12.2 0.0 0.075 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.15 EMC97747.1 - 0.17 11.5 4.2 1.3 8.7 0.2 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) SET PF00856.23 EMC97748.1 - 3.5e-17 63.1 2.6 3.4e-16 59.9 0.1 3.3 2 0 0 2 2 2 1 SET domain zf-DHHC PF01529.15 EMC97749.1 - 6.6e-36 123.3 0.1 1.9e-35 121.8 0.0 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase Slu7 PF11708.3 EMC97751.1 - 7.1e-70 235.4 13.9 7.1e-70 235.4 9.6 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EMC97751.1 - 0.013 15.1 1.0 0.027 14.1 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Glyoxal_oxid_N PF07250.6 EMC97752.1 - 4.4e-40 137.2 0.0 1.4e-39 135.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EMC97752.1 - 2.4e-22 78.8 0.7 5.5e-22 77.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EMC97752.1 - 3.7e-11 42.8 49.9 7.6e-06 25.8 15.3 2.8 2 0 0 2 2 2 2 Chitin recognition protein Pyridox_oxidase PF01243.15 EMC97752.1 - 0.0086 16.0 0.0 0.48 10.4 0.0 2.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Fructosamin_kin PF03881.9 EMC97753.1 - 8.2e-78 261.2 0.0 9.8e-78 261.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EMC97753.1 - 7.5e-05 22.5 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EMC97753.1 - 0.0026 16.4 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EMC97753.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase ERG4_ERG24 PF01222.12 EMC97754.1 - 8.9e-135 449.5 24.3 1.1e-134 449.2 16.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family RVT_thumb PF06817.9 EMC97755.1 - 0.067 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain YlaH PF14036.1 EMC97755.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 YlaH-like protein DUF4119 PF13494.1 EMC97756.1 - 0.21 11.6 1.4 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) CDK2AP PF09806.4 EMC97758.1 - 0.16 12.1 6.4 0.079 13.1 3.1 1.5 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein TRAP_alpha PF03896.11 EMC97759.1 - 2.5e-10 39.8 0.4 1.3e-09 37.4 0.3 2.1 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Vps16_N PF04841.8 EMC97761.1 - 9.2e-97 324.1 0.0 1.2e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EMC97761.1 - 5.5e-89 298.2 0.6 8.5e-89 297.6 0.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Phasin_2 PF09361.5 EMC97761.1 - 0.11 12.5 1.3 0.41 10.6 0.7 2.2 1 1 1 2 2 2 0 Phasin protein DUF2129 PF09902.4 EMC97762.1 - 0.028 14.2 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) Bestrophin PF01062.16 EMC97763.1 - 7.4e-47 159.6 0.0 2.1e-46 158.2 0.0 1.6 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel HA2 PF04408.18 EMC97764.1 - 2.2e-18 66.1 0.2 9.1e-18 64.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMC97764.1 - 6.4e-15 54.9 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMC97764.1 - 6.8e-14 51.4 1.2 2.5e-13 49.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RWD PF05773.17 EMC97764.1 - 2.9e-10 40.0 0.0 5.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EMC97764.1 - 5.1e-08 32.5 0.3 1.4e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase UBA PF00627.26 EMC97764.1 - 9e-07 28.5 1.4 4.6e-05 23.1 0.4 3.0 3 0 0 3 3 2 1 UBA/TS-N domain AAA_22 PF13401.1 EMC97764.1 - 0.00026 21.1 0.3 0.00087 19.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMC97764.1 - 0.0012 18.3 0.1 0.0042 16.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EMC97764.1 - 0.014 14.2 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EMC97764.1 - 0.033 13.3 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 EMC97764.1 - 0.052 13.0 0.1 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zot PF05707.7 EMC97764.1 - 0.099 12.0 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 EMC97764.1 - 0.11 12.7 0.3 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain DUF89 PF01937.14 EMC97764.1 - 0.12 11.1 0.1 0.71 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF89 EHN PF06441.7 EMC97765.1 - 5.6e-31 106.7 0.1 1.2e-30 105.7 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 EMC97765.1 - 8.2e-07 28.8 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC97765.1 - 2.7e-05 24.1 0.1 5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_2 PF00797.12 EMC97767.1 - 9.5e-41 139.9 0.0 2.4e-40 138.6 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 EMC97767.1 - 0.0033 17.6 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F_bP_aldolase PF01116.15 EMC97768.1 - 7.1e-79 264.8 0.4 8e-79 264.7 0.3 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Mannosyl_trans3 PF11051.3 EMC97768.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Epimerase PF01370.16 EMC97769.1 - 3.3e-22 79.0 0.0 4.2e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC97769.1 - 1.1e-11 43.9 0.0 1.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMC97769.1 - 1.1e-06 27.7 0.0 0.0062 15.4 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EMC97769.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC97769.1 - 2.4e-06 26.6 0.0 7.9e-06 24.9 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMC97769.1 - 0.00058 19.8 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Ldh_1_N PF00056.18 EMC97769.1 - 0.0091 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 EMC97769.1 - 0.055 13.1 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 KR domain DapB_N PF01113.15 EMC97769.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Acid_PPase PF12689.2 EMC97770.1 - 3.3e-61 205.7 0.0 3.9e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EMC97770.1 - 0.022 14.9 0.2 0.23 11.6 0.0 2.4 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase YTH PF04146.10 EMC97771.1 - 4.4e-11 42.5 0.0 6.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain HORMA PF02301.13 EMC97773.1 - 1.5e-19 70.3 0.0 4e-19 68.9 0.0 1.7 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 EMC97773.1 - 9.4e-09 34.8 7.2 2.4e-08 33.5 5.0 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EMC97773.1 - 0.0084 15.8 1.9 0.022 14.4 1.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EMC97773.1 - 0.12 11.6 2.4 0.29 10.4 1.7 1.6 1 0 0 1 1 1 0 PHD-finger Nup96 PF12110.3 EMC97775.1 - 6.1e-59 199.4 0.2 9.2e-59 198.9 0.1 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EMC97775.1 - 5.2e-45 152.7 0.0 8.4e-45 152.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase GMC_oxred_N PF00732.14 EMC97776.1 - 6.6e-75 252.0 0.0 9.1e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC97776.1 - 3.9e-38 130.9 0.1 9e-38 129.8 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EMC97776.1 - 6.9e-05 22.8 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC97776.1 - 0.00017 20.6 0.8 0.00074 18.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC97776.1 - 0.00049 19.0 0.2 0.0014 17.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EMC97776.1 - 0.00051 19.1 0.1 0.00091 18.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EMC97776.1 - 0.0015 17.5 0.1 0.0022 16.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EMC97776.1 - 0.0066 14.9 0.0 0.011 14.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMC97776.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMC97776.1 - 0.019 14.9 0.0 0.066 13.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 EMC97776.1 - 0.021 15.2 0.1 0.063 13.6 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMC97776.1 - 0.15 10.6 0.1 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CFEM PF05730.6 EMC97777.1 - 2.4e-07 30.4 10.3 4.4e-07 29.6 7.1 1.5 1 0 0 1 1 1 1 CFEM domain Prenyltrans PF00432.16 EMC97778.1 - 2.2e-31 107.0 24.1 1.1e-09 37.6 0.7 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMC97778.1 - 1.4e-21 77.0 0.2 1e-12 48.4 0.0 3.7 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC97778.1 - 0.00024 21.0 0.1 0.0017 18.3 0.0 2.5 1 1 1 2 2 2 1 Prenyltransferase-like PalH PF08733.5 EMC97779.1 - 0.077 11.8 1.2 0.11 11.3 0.9 1.1 1 0 0 1 1 1 0 PalH/RIM21 Metallophos PF00149.23 EMC97780.1 - 1.2e-38 132.5 0.7 1.9e-38 131.8 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EMC97780.1 - 1.3e-14 54.0 0.5 4.5e-14 52.2 0.3 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EMC97780.1 - 2.6e-10 39.4 0.9 1.2e-08 33.9 0.2 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 EMC97780.1 - 0.015 15.1 0.0 0.073 12.9 0.0 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Na_Ca_ex PF01699.19 EMC97781.1 - 9.6e-44 148.3 39.1 1.4e-23 83.0 8.5 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein SNARE_assoc PF09335.6 EMC97781.1 - 0.07 13.3 0.2 0.07 13.3 0.1 3.7 3 2 0 3 3 3 0 SNARE associated Golgi protein MerR PF00376.18 EMC97782.1 - 0.077 12.5 0.0 0.35 10.4 0.0 2.1 1 0 0 1 1 1 0 MerR family regulatory protein DUF2738 PF10927.3 EMC97783.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) ABC1 PF03109.11 EMC97784.1 - 3.4e-22 78.6 0.0 8.3e-22 77.3 0.0 1.7 1 1 0 1 1 1 1 ABC1 family APH PF01636.18 EMC97784.1 - 0.021 14.5 2.7 0.078 12.6 0.1 2.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family p450 PF00067.17 EMC97785.1 - 3.4e-65 220.3 0.0 4.3e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DFP PF04127.10 EMC97787.1 - 5e-14 52.3 0.0 7.2e-05 22.4 0.0 3.3 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.11 EMC97788.1 - 7.8e-35 120.2 20.4 7.8e-35 120.2 14.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily EI24 PF07264.6 EMC97789.1 - 0.00014 21.3 8.9 0.00049 19.6 6.1 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.1 EMC97789.1 - 0.79 9.6 3.4 7.5 6.5 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4112) Tannase PF07519.6 EMC97790.1 - 6.3e-111 371.4 4.1 1.1e-110 370.6 2.9 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EMC97790.1 - 0.00013 21.6 0.1 0.15 11.8 0.1 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC97790.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold CRAL_TRIO PF00650.15 EMC97792.1 - 5.1e-36 123.5 0.0 6.6e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC97792.1 - 2e-08 34.2 0.0 4.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF3926 PF13080.1 EMC97792.1 - 0.021 14.3 0.1 0.051 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) CRAL_TRIO_2 PF13716.1 EMC97792.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EMC97793.1 - 3.2e-62 210.3 0.1 4.2e-62 209.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EMC97793.1 - 3.4e-33 114.6 0.1 4.7e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Phosducin PF02114.11 EMC97794.1 - 1.1e-10 40.6 0.7 1.9e-06 26.8 0.6 3.0 2 1 0 2 2 2 2 Phosducin adh_short PF00106.20 EMC97796.1 - 3e-12 46.7 0.0 5.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC97796.1 - 0.00018 21.2 0.1 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 EMC97797.1 - 3.3e-51 169.4 17.8 3.6e-08 32.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC97797.1 - 5.9e-05 22.8 0.0 0.027 14.1 0.0 2.7 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ribosomal_S14 PF00253.16 EMC97799.1 - 8e-18 63.5 4.1 8.6e-18 63.4 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EMC97799.1 - 0.13 12.0 0.2 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.7 EMC97799.1 - 0.61 10.1 3.8 9.3 6.4 0.3 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Apc13p PF05839.6 EMC97800.1 - 1.6e-27 95.2 0.0 1.9e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Apc13p protein GCV_H PF01597.14 EMC97801.1 - 7.2e-44 148.3 0.6 8.9e-44 148.0 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EMC97801.1 - 0.00025 20.6 1.2 0.00083 18.9 0.6 1.9 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 EMC97801.1 - 0.00066 19.3 0.1 0.00097 18.8 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF849 PF05853.7 EMC97801.1 - 0.033 13.0 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Biotin_lipoyl_2 PF13533.1 EMC97801.1 - 0.089 12.4 0.4 16 5.2 0.0 2.9 2 1 1 3 3 3 0 Biotin-lipoyl like Ribosomal_S6 PF01250.12 EMC97802.1 - 4.1e-11 42.5 0.0 5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3414 PF11894.3 EMC97803.1 - 4.2e-277 922.3 11.6 5.6e-277 921.9 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 EMC97804.1 - 1.2e-46 159.1 0.0 3e-46 157.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EMC97804.1 - 4.3e-35 120.7 0.0 1.9e-34 118.6 0.0 2.2 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EMC97804.1 - 5.2e-10 38.5 0.1 1.5e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 FATC domain IF-2B PF01008.12 EMC97805.1 - 6.1e-76 255.0 0.0 7.6e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Plasmodium_Vir PF05795.6 EMC97805.1 - 0.11 11.6 0.4 0.16 11.1 0.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.5 EMC97805.1 - 2.9 6.2 4.7 3.6 5.8 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_B PF02304.10 EMC97805.1 - 5.1 7.4 7.1 6.6 7.0 3.9 2.0 1 1 0 1 1 1 0 Scaffold protein B Zn_clus PF00172.13 EMC97806.1 - 1.9e-07 30.8 13.9 3e-07 30.2 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1092 PF06485.6 EMC97806.1 - 0.027 13.4 0.0 0.06 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) adh_short PF00106.20 EMC97807.1 - 3.7e-18 66.0 0.0 5.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97807.1 - 1.1e-06 28.6 0.0 1.5e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97807.1 - 0.0001 22.0 0.2 0.0024 17.5 0.0 2.1 2 0 0 2 2 2 1 KR domain ThiC-associated PF13667.1 EMC97807.1 - 0.045 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 ThiC-associated domain MKT1_C PF12246.3 EMC97808.1 - 3.2e-45 154.0 0.0 3.9e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication ABC_tran PF00005.22 EMC97809.1 - 1.6e-14 54.3 0.3 3.7e-13 49.9 0.2 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC97809.1 - 9.5e-10 38.9 1.8 0.00033 20.7 0.2 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EMC97809.1 - 0.00013 21.1 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMC97809.1 - 0.00064 19.1 0.1 0.0015 18.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EMC97809.1 - 0.0016 15.8 0.2 0.002 15.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PduV-EutP PF10662.4 EMC97809.1 - 0.0049 16.3 0.1 0.0087 15.5 0.1 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 EMC97809.1 - 0.0053 16.0 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC97809.1 - 0.0069 16.3 0.5 0.015 15.2 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EMC97809.1 - 0.014 15.7 0.2 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMC97809.1 - 0.018 14.4 0.2 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMC97809.1 - 0.032 14.1 0.5 0.063 13.2 0.3 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EMC97809.1 - 0.032 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMC97809.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EMC97809.1 - 0.048 14.4 0.1 0.082 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMC97809.1 - 0.092 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EMC97809.1 - 0.12 12.5 1.7 0.78 9.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMC97809.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 EMC97809.1 - 0.15 10.7 0.2 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 EMC97809.1 - 0.16 12.1 0.1 0.84 9.8 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 EMC97809.1 - 0.2 10.0 0.0 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain IPPT PF01715.12 EMC97810.1 - 9.6e-55 185.3 0.2 3e-54 183.7 0.1 1.8 1 1 0 1 1 1 1 IPP transferase AAA_33 PF13671.1 EMC97810.1 - 6.1e-07 29.4 1.5 3.2e-05 23.8 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC97810.1 - 1.7e-06 28.3 2.0 0.0013 19.0 0.1 3.0 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EMC97810.1 - 5.1e-06 27.3 4.5 0.00013 22.7 2.6 2.9 1 1 1 2 2 2 1 AAA domain IPT PF01745.11 EMC97810.1 - 1.5e-05 24.3 0.0 3.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase zf-C2H2_jaz PF12171.3 EMC97810.1 - 3.6e-05 23.7 1.9 8.2e-05 22.6 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC97810.1 - 0.00028 20.9 1.9 0.00058 19.9 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_22 PF13401.1 EMC97810.1 - 0.0095 16.0 0.1 0.044 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMC97810.1 - 0.037 13.9 2.2 0.046 13.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EMC97810.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Hpr_kinase_C PF07475.7 EMC97810.1 - 0.063 12.5 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_25 PF13481.1 EMC97810.1 - 0.066 12.6 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EMC97810.1 - 0.074 12.8 0.8 0.49 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 zf-C2H2_2 PF12756.2 EMC97810.1 - 0.11 12.6 0.8 0.2 11.7 0.5 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF427 PF04248.7 EMC97811.1 - 4.6e-28 96.7 0.9 5.2e-28 96.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) RAMP PF04901.8 EMC97811.1 - 0.0024 17.6 0.1 0.0033 17.1 0.1 1.1 1 0 0 1 1 1 1 Receptor activity modifying family SUN PF03856.8 EMC97811.1 - 0.056 12.7 0.4 0.058 12.6 0.3 1.1 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) Peptidase_M16_C PF05193.16 EMC97813.1 - 3e-44 150.9 0.1 1e-41 142.6 0.0 2.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMC97813.1 - 1.1e-39 135.5 0.0 2.2e-39 134.6 0.0 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Myf5 PF12232.3 EMC97813.1 - 0.07 13.7 0.5 0.16 12.5 0.3 1.6 1 0 0 1 1 1 0 Myogenic determination factor 5 FHA PF00498.21 EMC97814.1 - 3.9e-16 58.9 0.0 6.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EMC97814.1 - 2.2e-08 33.7 8.3 3.8e-08 33.0 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC97814.1 - 4.2e-05 23.5 3.7 8.6e-05 22.5 2.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC97814.1 - 6.9e-05 22.4 7.7 0.00013 21.5 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC97814.1 - 0.00022 20.8 6.5 0.00039 20.0 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC97814.1 - 0.00046 19.9 1.7 0.00085 19.1 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.4 EMC97814.1 - 0.0013 18.9 0.2 0.002 18.2 0.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING-like PF08746.6 EMC97814.1 - 0.0036 17.2 5.3 0.008 16.1 3.7 1.6 1 0 0 1 1 1 1 RING-like domain zf-C3HC4_2 PF13923.1 EMC97814.1 - 0.0069 16.3 9.3 0.0069 16.3 6.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMC97814.1 - 0.014 15.0 5.3 0.037 13.7 3.7 1.7 1 0 0 1 1 1 0 PHD-finger GTP_EFTU PF00009.22 EMC97816.1 - 1.1e-31 109.6 0.0 2.1e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EMC97816.1 - 1.1e-13 50.8 0.0 4.7e-13 48.8 0.0 2.2 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMC97816.1 - 1.3e-09 38.0 0.0 5.2e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMC97816.1 - 2.9e-08 33.4 0.0 6.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EMC97816.1 - 0.00032 20.2 0.0 0.022 14.3 0.0 2.8 1 1 0 1 1 1 1 Elongation factor G, domain IV SET PF00856.23 EMC97816.1 - 0.0019 18.4 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 SET domain XLF PF09302.6 EMC97816.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 XLF (XRCC4-like factor) PH PF00169.24 EMC97817.1 - 5e-26 90.9 0.4 1.4e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC97817.1 - 9.2e-11 41.9 1.6 6.3e-06 26.4 0.0 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EMC97817.1 - 6.5e-08 32.7 2.4 0.0017 18.4 0.4 3.7 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 EMC97817.1 - 2e-06 27.8 0.3 8.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EMC97817.1 - 0.00039 20.2 0.4 0.034 14.0 0.1 2.6 2 1 0 2 2 2 1 PH domain CheF-arch PF04283.7 EMC97817.1 - 0.0011 18.1 0.1 1.3 8.2 0.0 2.1 2 0 0 2 2 2 2 Chemotaxis signal transduction system protein F from archaea Mcp5_PH PF12814.2 EMC97817.1 - 0.0058 16.5 1.6 0.48 10.3 0.2 2.2 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology ACT_3 PF10000.4 EMC97817.1 - 0.13 11.9 0.0 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 ACT domain DUF3722 PF12519.3 EMC97818.1 - 2e-89 299.2 0.2 2.5e-89 298.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EMC97818.1 - 0.0004 19.7 0.0 3.2 6.9 0.0 3.5 3 1 0 3 3 3 2 Eukaryotic porin AMP-binding PF00501.23 EMC97819.1 - 5.6e-77 258.8 0.0 6.5e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC97819.1 - 9e-17 61.8 0.1 8.9e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Kinesin PF00225.18 EMC97820.1 - 1e-111 372.9 0.8 1.4e-111 372.4 0.6 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF904 PF06005.7 EMC97820.1 - 0.00034 20.8 0.0 0.039 14.2 0.0 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF904) Mnd1 PF03962.10 EMC97820.1 - 0.0027 17.3 4.6 0.0063 16.2 3.2 1.6 1 0 0 1 1 1 1 Mnd1 family TPR_MLP1_2 PF07926.7 EMC97820.1 - 0.0027 17.4 11.8 0.006 16.3 8.2 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EMC97820.1 - 0.28 8.9 3.5 0.43 8.3 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAPS_reduct PF01507.14 EMC97820.1 - 0.47 10.2 2.7 5.5 6.7 1.0 2.3 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Spc7 PF08317.6 EMC97820.1 - 0.5 8.9 7.2 0.85 8.2 5.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.8 EMC97820.1 - 1.7 9.0 9.1 10 6.5 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF87 PF01935.12 EMC97820.1 - 3.5 7.3 9.0 0.56 9.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 IncA PF04156.9 EMC97820.1 - 5.9 6.4 7.8 13 5.2 5.4 1.6 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EMC97821.1 - 1.6e-46 158.6 52.2 9.4e-46 156.1 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC97821.1 - 5.2e-06 25.3 20.4 3.4e-05 22.6 14.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter FPN1 PF06963.7 EMC97821.1 - 0.014 13.7 0.0 0.035 12.4 0.0 1.6 1 0 0 1 1 1 0 Ferroportin1 (FPN1) PepSY_TM_2 PF13703.1 EMC97821.1 - 1.2 9.3 9.4 0.1 12.7 0.4 3.3 3 0 0 3 3 3 0 PepSY-associated TM helix SpoU_methylase PF00588.14 EMC97822.1 - 1.6e-27 96.1 0.0 2.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family PV-1 PF06637.6 EMC97822.1 - 0.059 11.9 0.1 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) WD40 PF00400.27 EMC97825.1 - 2.2e-56 185.8 20.0 3.9e-09 36.0 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EMC97825.1 - 5.7e-11 41.9 0.1 1.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC97825.1 - 4.2e-07 29.4 0.1 1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EMC97825.1 - 3.4e-05 23.4 1.2 0.17 11.3 0.2 2.8 2 1 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EMC97825.1 - 0.014 13.5 7.1 1 7.4 0.2 4.4 2 1 3 5 5 5 0 Nucleoporin Nup120/160 PBCV_basic_adap PF08789.5 EMC97825.1 - 1.1 8.9 2.6 0.58 9.8 0.1 1.8 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain LRR_6 PF13516.1 EMC97826.1 - 0.003 17.4 0.2 3.4 8.0 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.2 EMC97826.1 - 0.045 13.3 0.4 0.86 9.3 0.3 2.6 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC97826.1 - 0.077 13.0 0.1 3.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat DUF3425 PF11905.3 EMC97827.1 - 3e-23 82.2 0.5 3e-23 82.2 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EMC97827.1 - 0.0095 15.8 8.4 0.014 15.3 5.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor ATP13 PF12921.2 EMC97827.1 - 0.21 10.9 0.0 0.49 9.7 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial ATPase expression Hexapep PF00132.19 EMC97828.1 - 3.6e-11 42.0 13.9 0.00076 18.8 1.1 5.1 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Lactamase_B_5 PF14597.1 EMC97828.1 - 0.0021 17.5 0.1 0.0036 16.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily T2SS-T3SS_pil_N PF13629.1 EMC97828.1 - 0.028 13.9 0.9 0.2 11.1 0.1 2.2 2 0 0 2 2 2 0 Pilus formation protein N terminal region Hexapep_2 PF14602.1 EMC97828.1 - 0.46 10.0 13.1 0.22 11.1 1.2 3.3 2 2 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase KIF1B PF12423.3 EMC97829.1 - 0.21 11.6 2.3 0.5 10.4 0.0 2.6 2 2 0 2 2 2 0 Kinesin protein 1B DUF1295 PF06966.7 EMC97831.1 - 1.4e-43 148.9 0.2 5.6e-42 143.6 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EMC97831.1 - 0.0066 16.5 0.0 0.065 13.3 0.0 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EMC97831.1 - 0.047 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EMC97831.1 - 0.059 13.5 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Amino_oxidase PF01593.19 EMC97833.1 - 3.3e-52 178.0 0.2 1.9e-51 175.5 0.2 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMC97833.1 - 1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMC97833.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Competence PF03772.11 EMC97834.1 - 0.099 11.6 5.6 0.12 11.3 3.9 1.1 1 0 0 1 1 1 0 Competence protein Glyco_hydro_16 PF00722.16 EMC97835.1 - 9.2e-17 60.9 0.0 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GTP_EFTU PF00009.22 EMC97836.1 - 3e-61 206.1 0.2 4e-61 205.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMC97836.1 - 1.9e-27 95.3 0.0 1.1e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMC97836.1 - 2.1e-17 62.9 2.3 2.6e-17 62.6 0.7 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC97836.1 - 9.2e-06 25.6 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC97836.1 - 0.00077 19.9 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EMC97836.1 - 0.002 17.6 0.3 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 EMC97836.1 - 0.0087 15.6 0.4 0.04 13.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Gtr1_RagA PF04670.7 EMC97836.1 - 0.17 11.0 0.2 0.52 9.4 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ECH_C PF13766.1 EMC97837.1 - 8.9e-33 112.9 0.0 3.2e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EMC97837.1 - 6.3e-28 97.5 0.0 1e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family RNA_pol_Rpc4 PF05132.9 EMC97838.1 - 4.1e-26 91.5 0.0 9.7e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase III RPC4 Fringe PF02434.11 EMC97839.1 - 2.2e-08 33.6 0.4 2e-07 30.5 0.3 2.0 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EMC97839.1 - 0.00019 21.0 1.1 0.00053 19.6 0.7 1.7 1 0 0 1 1 1 1 PAN domain Ribosomal_L32e PF01655.13 EMC97842.1 - 2.5e-51 172.3 1.3 3e-51 172.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Gp_UL130 PF11668.3 EMC97842.1 - 0.027 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 COPR5 PF15340.1 EMC97842.1 - 0.13 12.5 0.0 2 8.7 0.0 2.0 2 0 0 2 2 2 0 Cooperator of PRMT5 family Ribosomal_L10 PF00466.15 EMC97843.1 - 2.4e-15 56.2 0.0 3.6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 priB_priC PF07445.7 EMC97845.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Primosomal replication protein priB and priC SGL PF08450.7 EMC97846.1 - 5.7e-24 84.8 0.1 9.9e-24 84.0 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EMC97846.1 - 7.5e-06 25.8 0.1 2.3e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 EMC97846.1 - 0.00024 21.0 0.0 0.0015 18.5 0.0 2.4 2 1 0 2 2 2 1 Strictosidine synthase Sugar_tr PF00083.19 EMC97848.1 - 1.7e-07 30.1 0.4 2e-07 29.9 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EMC97848.1 - 0.068 11.5 0.7 0.077 11.3 0.5 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein ADH_zinc_N_2 PF13602.1 EMC97851.1 - 2.5e-20 73.6 0.0 4.6e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMC97851.1 - 1.5e-12 47.2 0.2 2.9e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2422 PF10337.4 EMC97852.1 - 1.6e-80 271.1 8.8 1.6e-80 271.1 6.1 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EMC97852.1 - 2.1e-13 50.3 14.2 2.1e-13 50.3 9.8 3.1 2 2 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EMC97852.1 - 2.2e-13 50.3 0.0 1.3e-12 47.8 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) Asp PF00026.18 EMC97853.1 - 3.6e-68 230.1 9.5 4.3e-68 229.8 6.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC97853.1 - 3e-07 30.5 0.0 1.7e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMC97853.1 - 2.9e-06 27.6 3.4 0.031 14.7 0.2 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMC97853.1 - 0.013 15.0 0.1 0.053 13.0 0.0 2.2 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal adh_short PF00106.20 EMC97854.1 - 2.5e-07 30.7 2.6 0.0016 18.4 1.0 3.4 2 1 0 2 2 2 2 short chain dehydrogenase Alb1 PF09135.6 EMC97855.1 - 4.5e-16 59.4 8.5 6.8e-16 58.8 5.9 1.3 1 0 0 1 1 1 1 Alb1 L31 PF09784.4 EMC97855.1 - 0.037 14.0 1.6 0.066 13.2 1.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DivIC PF04977.10 EMC97855.1 - 0.18 11.3 3.8 0.28 10.7 1.5 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF4337 PF14235.1 EMC97855.1 - 0.79 9.5 3.7 1.3 8.8 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) UCH PF00443.24 EMC97856.1 - 9.7e-39 133.0 0.0 1.4e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC97856.1 - 3.3e-12 46.4 0.0 5.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2348 PF09807.4 EMC97857.1 - 9.4e-05 21.6 0.1 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) FliC PF12445.3 EMC97857.1 - 0.2 11.7 2.9 1.1 9.4 2.2 2.1 1 1 1 2 2 2 0 Flagellin protein Git3 PF11710.3 EMC97858.1 - 1.6e-21 76.8 9.8 5.4e-21 75.0 6.8 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EMC97858.1 - 5.4e-07 29.2 1.5 8e-07 28.7 0.0 2.1 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EMC97858.1 - 2.1e-05 23.8 3.9 2.1e-05 23.8 2.7 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EMC97858.1 - 0.78 8.5 11.8 0.12 11.2 4.7 2.0 2 1 0 2 2 2 0 Slime mold cyclic AMP receptor RdRP PF05183.7 EMC97859.1 - 2.4e-171 571.3 0.0 3.2e-171 570.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_13 PF13166.1 EMC97860.1 - 0.00086 17.8 3.7 0.00086 17.8 2.5 2.1 1 1 1 2 2 2 2 AAA domain Myosin_tail_1 PF01576.14 EMC97860.1 - 0.0011 16.8 41.4 0.0018 16.1 28.2 1.5 1 1 0 1 1 1 1 Myosin tail Filament PF00038.16 EMC97860.1 - 0.028 13.8 35.1 0.88 8.9 4.5 2.8 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EMC97860.1 - 0.029 13.5 9.4 0.12 11.5 2.2 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF948 PF06103.6 EMC97860.1 - 0.11 12.3 0.8 5 7.0 0.1 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.6 EMC97860.1 - 0.31 10.8 34.6 0.42 10.4 1.7 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA_27 PF13514.1 EMC97860.1 - 0.34 8.5 40.8 0.57 7.7 28.3 1.3 1 0 0 1 1 1 0 AAA domain ERM PF00769.14 EMC97860.1 - 2.2 7.7 42.9 0.46 9.9 11.0 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Spc7 PF08317.6 EMC97860.1 - 3.4 6.2 25.0 1.2 7.7 5.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EMC97860.1 - 4.5 7.3 25.2 0.69 9.9 0.1 4.4 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EMC97860.1 - 4.7 6.1 35.0 1.2 8.1 3.2 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 FAD-oxidase_C PF02913.14 EMC97861.1 - 1.3e-66 224.5 0.3 1.7e-66 224.1 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMC97861.1 - 2.2e-34 117.9 0.0 3.6e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EMC97861.1 - 0.12 10.8 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF3247 PF11607.3 EMC97862.1 - 0.035 14.3 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) PHBC_N PF12551.3 EMC97862.1 - 0.048 13.1 0.2 0.09 12.3 0.2 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal Methyltransf_2 PF00891.13 EMC97863.1 - 7.5e-31 107.1 0.0 1.3e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EMC97863.1 - 0.14 12.4 0.0 0.81 10.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Semialdhyde_dhC PF02774.13 EMC97864.1 - 3.8e-38 131.1 0.0 5.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EMC97864.1 - 9.6e-29 100.1 0.0 1.7e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMC97864.1 - 0.063 12.2 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Gp_dh_C PF02800.15 EMC97864.1 - 0.082 12.3 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 EMC97864.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 EMC97864.1 - 0.13 12.1 0.0 0.44 10.4 0.0 1.9 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Hydrolase_6 PF13344.1 EMC97865.1 - 1.1e-22 79.7 0.0 3e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC97865.1 - 2.7e-18 65.4 0.0 1.1e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EMC97865.1 - 0.00012 22.5 0.0 0.32 11.3 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC97865.1 - 0.00017 21.8 0.1 0.14 12.3 0.0 3.1 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC97865.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_M43 PF05572.8 EMC97865.1 - 0.14 11.7 0.1 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Bac_rhodopsin PF01036.13 EMC97866.1 - 3e-63 213.1 13.8 3.8e-63 212.7 9.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein YjgP_YjgQ PF03739.9 EMC97866.1 - 0.16 10.6 0.1 0.16 10.6 0.0 1.9 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Oxidored_q3 PF00499.15 EMC97866.1 - 0.42 10.3 6.4 0.2 11.4 1.8 2.2 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DAO PF01266.19 EMC97867.1 - 1.6e-16 60.2 0.2 1.8e-07 30.3 0.0 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMC97867.1 - 3.8e-15 55.9 0.1 1.2e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMC97867.1 - 5.2e-13 48.8 0.1 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMC97867.1 - 1.8e-06 27.0 1.9 1.1e-05 24.4 0.9 2.3 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC97867.1 - 7.7e-06 25.9 0.0 4.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC97867.1 - 9.7e-06 24.9 0.0 0.00011 21.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMC97867.1 - 2.3e-05 23.0 0.1 0.0006 18.3 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EMC97867.1 - 0.00024 20.2 0.2 0.00045 19.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMC97867.1 - 0.00052 20.3 2.3 0.18 12.2 0.5 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EMC97867.1 - 0.0019 17.4 0.2 0.028 13.5 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.17 EMC97867.1 - 0.0022 16.9 0.6 0.0034 16.2 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMC97867.1 - 0.0038 16.3 0.3 0.008 15.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC97867.1 - 0.0043 17.1 0.0 0.083 12.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EMC97867.1 - 0.011 14.0 0.0 0.68 8.1 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 EMC97867.1 - 0.048 13.3 0.4 0.086 12.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EMC97867.1 - 0.066 12.1 0.4 0.18 10.7 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EMC97867.1 - 0.081 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EMC97867.1 - 0.083 12.6 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.16 EMC97867.1 - 0.16 11.8 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 EMC97867.1 - 0.19 11.1 0.3 0.36 10.2 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SQS_PSY PF00494.14 EMC97868.1 - 4.6e-64 216.2 0.2 6e-64 215.9 0.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.10 EMC97869.1 - 3.1e-135 451.4 0.0 3.9e-135 451.1 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SLAC1 PF03595.12 EMC97870.1 - 2e-84 283.0 57.2 2.3e-84 282.8 39.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel NIF PF03031.13 EMC97870.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Cyclin_N PF00134.18 EMC97871.1 - 2.1e-12 46.6 0.0 4e-12 45.8 0.0 1.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 EMC97871.1 - 2.9e-11 43.9 0.0 4.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin RA PF00788.18 EMC97873.1 - 9.7e-14 51.6 0.0 2.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EMC97873.1 - 5.6e-10 39.2 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC97873.1 - 9.8e-09 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GST_C_2 PF13410.1 EMC97873.1 - 0.00019 21.2 0.0 0.00048 19.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC97873.1 - 0.008 16.1 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC97873.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SAM_PNT PF02198.11 EMC97873.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AAA PF00004.24 EMC97874.1 - 1.6e-96 319.5 0.0 5.2e-47 159.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMC97874.1 - 4.1e-21 74.7 0.5 1.2e-20 73.2 0.3 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EMC97874.1 - 1.1e-13 51.4 0.0 1.4e-07 31.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EMC97874.1 - 3.5e-13 49.6 0.0 2.1e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EMC97874.1 - 9.6e-13 47.7 0.0 4.3e-05 22.6 0.0 2.9 3 1 1 4 4 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMC97874.1 - 1.5e-11 44.2 0.6 7.8e-06 25.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMC97874.1 - 3.1e-11 43.5 0.2 0.0032 17.6 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMC97874.1 - 3.2e-11 44.0 0.0 0.00039 21.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMC97874.1 - 2.6e-10 40.6 0.0 0.00085 19.3 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EMC97874.1 - 5e-09 35.3 0.0 0.0013 17.5 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EMC97874.1 - 4.9e-08 32.5 0.0 0.0064 15.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EMC97874.1 - 1.4e-07 31.1 1.5 0.004 16.8 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 EMC97874.1 - 1.6e-07 30.9 4.9 0.031 13.6 0.0 4.5 2 2 1 4 4 4 2 AAA domain Mg_chelatase PF01078.16 EMC97874.1 - 2e-07 30.3 0.3 0.03 13.4 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EMC97874.1 - 2.5e-07 30.6 0.0 0.0062 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMC97874.1 - 3.7e-07 29.4 0.0 0.0059 15.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 EMC97874.1 - 1.8e-06 28.0 0.0 0.026 14.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 EMC97874.1 - 2e-06 27.0 1.0 0.36 9.9 0.0 3.5 2 1 1 3 3 3 2 KaiC CDC48_2 PF02933.12 EMC97874.1 - 2.6e-06 26.9 0.0 7.2e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.1 EMC97874.1 - 4.2e-06 27.0 0.0 0.069 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EMC97874.1 - 7.2e-06 25.9 0.0 0.0067 16.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EMC97874.1 - 1.1e-05 25.4 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EMC97874.1 - 3.6e-05 22.8 0.0 0.017 14.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EMC97874.1 - 4.2e-05 23.2 0.3 0.16 11.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EMC97874.1 - 4.9e-05 22.8 0.1 0.45 9.9 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EMC97874.1 - 5.5e-05 22.4 0.3 0.3 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EMC97874.1 - 7.4e-05 22.8 0.0 0.37 10.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EMC97874.1 - 8.6e-05 21.5 0.1 0.082 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EMC97874.1 - 0.00011 22.0 0.0 6 6.4 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase ABC_tran PF00005.22 EMC97874.1 - 0.00013 22.2 0.0 0.35 11.1 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 EMC97874.1 - 0.00018 21.2 0.0 2 7.9 0.0 3.3 3 0 0 3 3 3 2 Bacterial dnaA protein Vps4_C PF09336.5 EMC97874.1 - 0.00064 19.5 0.1 0.0019 18.0 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EMC97874.1 - 0.00069 19.2 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMC97874.1 - 0.00086 18.9 0.0 0.87 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMC97874.1 - 0.00088 18.9 0.1 0.63 9.6 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.1 EMC97874.1 - 0.001 18.7 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EMC97874.1 - 0.0013 17.7 0.0 0.63 8.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EMC97874.1 - 0.0036 17.0 0.2 1 9.0 0.0 3.5 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 EMC97874.1 - 0.0052 16.3 0.0 0.56 9.6 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EMC97874.1 - 0.0062 15.4 0.1 0.75 8.5 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain KAP_NTPase PF07693.9 EMC97874.1 - 0.019 13.9 0.0 1.1 8.2 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain IPT PF01745.11 EMC97874.1 - 0.026 13.7 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 EMC97874.1 - 0.033 13.0 0.0 2.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EMC97874.1 - 0.042 13.2 0.8 7.4 5.9 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain UFD1 PF03152.9 EMC97874.1 - 0.058 12.5 0.0 3.8 6.6 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Zot PF05707.7 EMC97874.1 - 0.061 12.7 0.1 36 3.7 0.0 4.0 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 EMC97874.1 - 0.13 11.4 0.1 20 4.3 0.0 2.8 3 0 0 3 3 2 0 Chromatin associated protein KTI12 cobW PF02492.14 EMC97875.1 - 1.7e-22 79.7 5.5 7.3e-15 54.8 0.2 3.1 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EMC97875.1 - 0.0017 17.2 1.7 0.033 12.9 0.0 2.8 1 1 1 3 3 3 1 ArgK protein CobW_C PF07683.9 EMC97875.1 - 0.0053 16.4 0.5 0.64 9.7 0.1 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain Glyco_hydro_31 PF01055.21 EMC97876.1 - 1.5e-172 574.4 3.8 1.9e-172 574.0 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 CBM_20 PF00686.14 EMC97876.1 - 4e-17 61.5 0.1 1.4e-16 59.8 0.1 2.0 1 0 0 1 1 1 1 Starch binding domain Gal_mutarotas_2 PF13802.1 EMC97876.1 - 6.4e-10 38.7 4.0 1.3e-09 37.7 1.0 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like Lactonase PF10282.4 EMC97877.1 - 3.6e-80 269.6 0.0 4.4e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HCV_NS4a PF01006.15 EMC97877.1 - 0.063 12.8 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a adh_short PF00106.20 EMC97878.1 - 8.8e-28 97.3 0.5 1.3e-27 96.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC97878.1 - 2.7e-15 56.8 0.1 3.8e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC97878.1 - 1.3e-10 41.2 1.0 1.6e-10 40.9 0.1 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMC97878.1 - 6.3e-05 23.0 0.4 0.00014 21.9 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC97878.1 - 0.00028 20.3 0.2 0.0006 19.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMC97878.1 - 0.0062 15.7 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EMC97878.1 - 0.0069 15.3 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EMC97878.1 - 0.012 15.3 0.2 0.031 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TPM PF04536.9 EMC97878.1 - 0.045 13.6 0.6 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase NmrA PF05368.8 EMC97878.1 - 0.056 12.6 0.1 0.091 11.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family SIP1 PF04938.7 EMC97879.1 - 1.6e-06 27.7 0.1 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Peptidase_M20 PF01546.23 EMC97880.1 - 2.3e-20 72.8 0.2 3.4e-20 72.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMC97880.1 - 2.7e-14 52.8 0.1 1.1e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain MIP PF00230.15 EMC97881.1 - 6.5e-48 163.1 17.6 7.5e-48 162.9 12.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein zf-RING_2 PF13639.1 EMC97883.1 - 9.7e-14 50.9 5.7 1.7e-13 50.1 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EMC97883.1 - 4.3e-10 39.1 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EMC97883.1 - 1.1e-09 38.2 0.9 2.2e-09 37.2 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC97883.1 - 2e-09 37.2 5.2 3.3e-09 36.6 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC97883.1 - 1e-08 34.6 3.1 1.7e-08 33.9 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC97883.1 - 3.6e-08 32.9 3.3 5.5e-08 32.3 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC97883.1 - 2.6e-07 30.2 2.4 4.2e-07 29.5 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC97883.1 - 0.00054 19.7 0.4 0.0011 18.7 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2029 PF09594.5 EMC97883.1 - 0.0053 16.2 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) zf-C3HC4_4 PF15227.1 EMC97883.1 - 0.091 12.6 4.0 0.2 11.5 2.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EMC97883.1 - 0.093 12.7 3.7 0.18 11.8 2.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EMC97883.1 - 0.11 12.2 2.6 0.24 11.1 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EMC97883.1 - 0.11 12.4 2.4 0.33 10.9 1.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EMC97883.1 - 0.97 9.0 2.5 1.8 8.2 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EMC97883.1 - 1.7 8.6 3.4 3.1 7.8 2.4 1.4 1 0 0 1 1 1 0 RING-like domain ANTH PF07651.11 EMC97884.1 - 8.7e-78 260.8 0.0 8.7e-78 260.8 0.0 3.4 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.12 EMC97884.1 - 1e-64 217.0 6.7 1e-64 217.0 4.6 5.3 5 1 0 6 6 6 1 I/LWEQ domain ENTH PF01417.15 EMC97884.1 - 3.3e-05 23.7 0.0 0.00025 20.8 0.0 2.6 1 0 0 1 1 1 1 ENTH domain TcdB_N PF12918.2 EMC97884.1 - 0.06 13.4 5.6 0.27 11.3 0.9 3.8 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain TFIIA PF03153.8 EMC97884.1 - 8.8 6.1 30.5 2.7 7.7 13.0 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S4e PF00900.15 EMC97885.1 - 1.7e-31 107.6 0.3 3.6e-31 106.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EMC97885.1 - 3.4e-16 58.7 1.0 6.7e-16 57.8 0.7 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EMC97885.1 - 5.4e-08 32.1 0.0 1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EMC97885.1 - 0.0042 16.7 0.8 0.0042 16.7 0.6 3.3 4 0 0 4 4 4 1 KOW motif Mito_carr PF00153.22 EMC97886.1 - 1e-19 70.0 4.6 4e-14 52.1 0.0 3.8 3 2 0 3 3 3 2 Mitochondrial carrier protein SPT16 PF08644.6 EMC97887.1 - 5.7e-56 188.5 0.0 5.7e-56 188.5 0.0 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EMC97887.1 - 2.3e-52 176.7 3.0 3e-52 176.4 0.3 2.5 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EMC97887.1 - 4e-26 91.8 0.0 6.4e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EMC97887.1 - 1e-22 79.9 0.1 6.6e-22 77.3 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF4291 PF14124.1 EMC97889.1 - 2.7e-56 190.0 2.0 6.5e-56 188.8 1.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4291) Claudin_2 PF13903.1 EMC97890.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction U1snRNP70_N PF12220.3 EMC97891.1 - 7e-27 93.5 0.5 1.3e-26 92.7 0.3 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EMC97891.1 - 2.1e-14 52.9 0.1 4.3e-06 26.2 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC97891.1 - 2.3e-11 43.4 0.1 7.1e-11 41.9 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC97891.1 - 0.00013 21.7 0.1 0.0011 18.8 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 EMC97892.1 - 1.6e-14 53.3 0.1 3e-14 52.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ebp2 PF05890.7 EMC97894.1 - 7.4e-86 287.8 14.8 7.4e-86 287.8 10.3 2.2 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 zf-DHHC PF01529.15 EMC97895.1 - 3e-40 137.4 0.3 6.2e-40 136.4 0.2 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EMC97895.1 - 0.072 12.8 1.5 1 9.1 0.8 2.4 2 0 0 2 2 2 0 Transglutaminase-like superfamily DZR PF12773.2 EMC97895.1 - 0.21 11.4 6.1 0.49 10.2 4.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_S24 PF00717.18 EMC97896.1 - 6.4e-07 28.9 0.0 9.8e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EMC97896.1 - 0.001 18.5 0.0 0.0093 15.4 0.0 2.1 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 FAD_binding_3 PF01494.14 EMC97897.1 - 1.9e-12 46.9 0.2 0.00076 18.6 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EMC97897.1 - 0.00017 21.5 0.1 0.00043 20.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC97897.1 - 0.0037 16.2 0.1 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC97897.1 - 0.0062 16.4 0.0 0.058 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC97897.1 - 0.018 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EMC97897.1 - 0.06 12.2 0.1 0.87 8.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMC97897.1 - 0.097 13.0 0.0 8.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EMC97900.1 - 4.8e-30 104.6 0.7 7.2e-30 104.0 0.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMC97900.1 - 5.5e-16 58.7 0.2 8.2e-16 58.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMC97900.1 - 2.8e-08 33.0 0.0 3.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EMC97900.1 - 5e-07 29.7 0.0 8.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC97900.1 - 1.5e-06 27.8 0.0 3.4e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC97900.1 - 0.00037 19.2 0.0 0.00052 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 EMC97900.1 - 0.0041 16.8 0.1 0.0087 15.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMC97900.1 - 0.018 15.0 0.6 0.029 14.3 0.4 1.4 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EMC97900.1 - 0.12 12.5 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EMC97900.1 - 0.13 11.4 0.7 0.17 11.1 0.5 1.2 1 0 0 1 1 1 0 NmrA-like family Cullin_binding PF03556.10 EMC97902.1 - 3.8e-31 107.6 6.4 6.6e-31 106.8 4.5 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EMC97902.1 - 6.6e-11 41.5 0.4 1.2e-10 40.7 0.3 1.5 1 0 0 1 1 1 1 UBA-like domain DNA_pol_B PF00136.16 EMC97903.1 - 5.4e-143 477.1 1.5 8.3e-143 476.5 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EMC97903.1 - 7e-84 281.4 0.1 1.3e-83 280.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EMC97903.1 - 4.8e-22 77.7 1.8 4.8e-22 77.7 1.2 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EMC97903.1 - 0.00055 19.5 0.1 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EMC97903.1 - 0.0022 17.8 0.2 0.0094 15.7 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EMC97903.1 - 0.033 12.8 2.5 0.052 12.2 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral Homeobox PF00046.24 EMC97904.1 - 4.2e-19 67.9 2.2 8.8e-19 66.8 1.5 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC97904.1 - 0.0012 18.4 0.3 0.0028 17.3 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain MAPEG PF01124.13 EMC97905.1 - 1.2e-18 66.9 1.8 1.4e-18 66.7 1.2 1.0 1 0 0 1 1 1 1 MAPEG family Sulfotransfer_3 PF13469.1 EMC97909.1 - 0.049 14.5 0.3 0.068 14.1 0.2 1.3 1 0 0 1 1 1 0 Sulfotransferase family Adaptin_binding PF10199.4 EMC97910.1 - 8.4e-11 42.2 4.3 1.2e-09 38.5 3.2 2.4 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF1275 PF06912.6 EMC97912.1 - 2e-36 125.1 8.4 2.7e-36 124.7 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DctQ PF04290.7 EMC97912.1 - 0.0095 15.7 1.4 0.0095 15.7 1.0 1.9 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2484 PF10658.4 EMC97912.1 - 0.021 14.9 1.0 0.021 14.9 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) OPT PF03169.10 EMC97912.1 - 0.022 13.1 0.2 0.022 13.1 0.1 1.9 2 0 0 2 2 2 0 OPT oligopeptide transporter protein NADH5_C PF06455.6 EMC97912.1 - 0.2 11.0 0.1 0.2 11.0 0.1 2.0 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus DUF3953 PF13129.1 EMC97912.1 - 1.1 8.8 6.2 45 3.7 2.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) DUF4131 PF13567.1 EMC97912.1 - 2.7 7.3 8.5 0.13 11.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_L18e PF00828.14 EMC97913.1 - 3.2e-16 59.8 0.1 5.2e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Bacteriocin_IIi PF11758.3 EMC97913.1 - 0.13 11.8 0.1 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin Glyco_transf_90 PF05686.7 EMC97914.1 - 7.1e-13 48.0 4.8 5.5e-05 22.0 0.2 4.0 3 1 0 3 3 3 3 Glycosyl transferase family 90 CRCB PF02537.10 EMC97917.1 - 0.058 13.2 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 CrcB-like protein Cyclin PF08613.6 EMC97918.1 - 1.9e-14 54.3 0.0 2.9e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMC97918.1 - 0.028 13.9 0.1 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain GDNF PF02351.11 EMC97919.1 - 0.057 13.9 0.9 0.18 12.3 0.6 1.8 1 0 0 1 1 1 0 GDNF/GAS1 domain DUF2392 PF10288.4 EMC97920.1 - 9.9e-27 93.3 0.0 1.8e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DUF3418 PF11898.3 EMC97920.1 - 0.12 10.7 0.1 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) DZR PF12773.2 EMC97920.1 - 1.9 8.3 6.3 7.1 6.5 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Bystin PF05291.6 EMC97922.1 - 2.4e-125 417.4 0.0 3.8e-125 416.8 0.0 1.2 1 0 0 1 1 1 1 Bystin DIOX_N PF14226.1 EMC97924.1 - 1.7e-23 83.3 0.0 2.6e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMC97924.1 - 2.9e-18 65.9 0.0 4.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 EMC97925.1 - 1.1e-30 107.1 0.2 1.5e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase LDB19 PF13002.2 EMC97927.1 - 4.1e-41 140.5 0.1 1.2e-40 139.1 0.1 1.7 2 1 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 EMC97927.1 - 2.5e-05 24.1 0.0 6.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF3072 PF11272.3 EMC97928.1 - 0.096 12.3 0.3 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Amidohydro_1 PF01979.15 EMC97929.1 - 3.5e-38 132.1 0.2 4.2e-38 131.8 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC97929.1 - 3.8e-18 66.5 0.4 7.1e-18 65.6 0.3 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC97929.1 - 1.2e-11 44.4 5.7 5.7e-10 38.9 1.1 2.5 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMC97929.1 - 5e-09 35.8 0.0 1.8e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase DeoC PF01791.4 EMC97929.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase COMPASS-Shg1 PF05205.7 EMC97930.1 - 5.8e-18 65.1 0.0 1.6e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 UPF0052 PF01933.13 EMC97932.1 - 4e-53 180.7 0.0 5.3e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 GFO_IDH_MocA PF01408.17 EMC97933.1 - 3e-23 82.6 0.1 5.2e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMC97933.1 - 2e-12 46.8 0.0 3.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EMC97933.1 - 0.0084 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain MFS_1 PF07690.11 EMC97934.1 - 2.6e-05 23.1 26.5 0.00031 19.5 16.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-MYND PF01753.13 EMC97935.1 - 1.2e-09 37.9 16.6 2.9e-09 36.6 11.5 1.7 1 1 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EMC97935.1 - 0.0081 15.7 10.7 0.018 14.6 7.4 1.6 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.8 EMC97935.1 - 2.3 5.7 5.5 2.7 5.5 3.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Na_H_Exchanger PF00999.16 EMC97937.1 - 3.5e-73 246.3 20.3 4.2e-73 246.0 14.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 EMC97937.1 - 9.6e-68 229.4 65.1 6.2e-67 226.7 45.1 1.9 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4190 PF13828.1 EMC97937.1 - 0.0034 16.8 2.9 0.18 11.3 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4190) YrhC PF14143.1 EMC97937.1 - 0.57 10.1 3.3 0.53 10.2 0.3 2.3 2 0 0 2 2 2 0 YrhC-like protein C1_3 PF07649.7 EMC97938.1 - 3.9 7.6 6.1 0.49 10.4 0.1 2.2 2 0 0 2 2 2 0 C1-like domain Mpv17_PMP22 PF04117.7 EMC97939.1 - 3.3e-13 49.0 0.6 8.1e-12 44.5 0.2 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family SprT-like PF10263.4 EMC97940.1 - 0.00012 21.8 0.0 0.0003 20.4 0.0 1.7 1 0 0 1 1 1 1 SprT-like family Cupin_8 PF13621.1 EMC97941.1 - 8e-65 218.8 0.0 1e-64 218.4 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMC97941.1 - 3.2e-06 26.6 0.1 0.0071 15.6 0.0 2.9 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.17 EMC97941.1 - 0.0087 16.2 0.0 0.26 11.5 0.0 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase EF-hand_4 PF12763.2 EMC97942.1 - 9.7e-06 25.2 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 EMC97942.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 EMC97942.1 - 0.087 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 EF hand DNA_ligase_A_M PF01068.16 EMC97943.1 - 7.5e-43 146.2 0.5 1.5e-42 145.2 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMC97943.1 - 3.5e-39 134.4 0.0 7.1e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EMC97943.1 - 4.4e-16 59.0 0.0 1.7e-15 57.1 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EMC97943.1 - 8.3e-09 35.4 0.0 4.6e-07 29.9 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 EMC97943.1 - 0.00023 20.8 0.1 0.00023 20.8 0.1 2.0 2 0 0 2 2 2 1 DNA ligase IV PTCB-BRCT PF12738.2 EMC97943.1 - 0.0014 18.4 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain DUF4604 PF15377.1 EMC97945.1 - 3.2e-22 79.4 12.2 3.9e-22 79.1 8.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Glyco_transf_15 PF01793.11 EMC97946.1 - 1.4e-133 444.9 2.5 1.9e-133 444.5 1.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase 4HBT_3 PF13622.1 EMC97947.1 - 3.4e-36 125.2 0.0 4.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMC97947.1 - 9.4e-06 25.2 2.4 0.001 18.6 0.7 3.4 2 2 1 3 3 3 1 Acyl-CoA thioesterase Sugar_tr PF00083.19 EMC97949.1 - 3.3e-126 421.5 40.1 3.7e-126 421.3 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC97949.1 - 1.4e-26 93.0 62.4 1.9e-24 86.0 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC97949.1 - 3.5e-09 35.5 36.6 3.8e-07 28.8 8.8 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein MFS_3 PF05977.8 EMC97949.1 - 5.1e-05 21.5 3.6 5.1e-05 21.5 2.5 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.8 EMC97949.1 - 0.00033 19.0 12.6 0.0042 15.3 3.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMC97949.1 - 0.077 12.7 0.1 0.077 12.7 0.1 4.2 4 1 0 4 4 4 0 MFS_1 like family ADH_N PF08240.7 EMC97950.1 - 1.8e-25 88.8 3.2 3.3e-25 87.9 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC97950.1 - 6.5e-16 58.0 0.1 1.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC97950.1 - 0.034 15.0 0.0 0.058 14.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EMC97950.1 - 0.09 12.3 0.2 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EMC97950.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3306 PF11748.3 EMC97950.1 - 0.15 12.7 0.2 0.25 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Pyr_redox_2 PF07992.9 EMC97951.1 - 3.3e-26 92.4 0.0 2.8e-25 89.4 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC97951.1 - 6.6e-12 45.6 0.0 2e-10 40.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC97951.1 - 0.00011 22.3 0.6 1.2 9.2 0.2 3.8 3 2 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pmp3 PF01679.12 EMC97952.1 - 3.2e-15 55.5 9.8 3.8e-15 55.2 6.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2217 PF10265.4 EMC97952.1 - 1.5 7.5 3.5 1.8 7.2 2.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Glyco_hydro_28 PF00295.12 EMC97953.1 - 2e-36 125.5 10.0 1.7e-35 122.5 4.7 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 DUF4598 PF15370.1 EMC97954.1 - 2.3e-17 63.3 4.3 3.8e-17 62.5 3.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) IF4E PF01652.13 EMC97955.1 - 1.6e-36 125.3 0.4 2e-36 125.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Porphobil_deam PF01379.15 EMC97956.1 - 5.4e-77 257.5 0.0 8e-77 256.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EMC97956.1 - 3.2e-18 65.5 0.0 6.6e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF2263 PF10021.4 EMC97958.1 - 1.8e-16 60.5 0.0 3.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) TRAPP PF04051.11 EMC97959.1 - 2.1e-36 124.7 0.0 2.5e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Las1 PF04031.8 EMC97960.1 - 3.2e-43 147.0 0.6 5.3e-43 146.3 0.4 1.4 1 0 0 1 1 1 1 Las1-like NAD_kinase PF01513.16 EMC97961.1 - 1.1e-67 227.7 0.0 1.6e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Arylsulfotran_2 PF14269.1 EMC97962.1 - 1.1e-80 270.9 0.1 1.4e-80 270.6 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMC97962.1 - 6.1e-12 44.7 0.0 7.6e-11 41.1 0.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DSPc PF00782.15 EMC97963.1 - 5e-29 100.5 0.0 5.6e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EMC97963.1 - 0.0013 17.7 0.0 0.0015 17.5 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 EMC97963.1 - 0.0018 18.3 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC97963.1 - 0.0067 16.6 0.0 0.012 15.8 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EMC97963.1 - 0.015 14.6 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase WD40 PF00400.27 EMC97964.1 - 1.8e-33 113.1 4.6 4e-08 32.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nbas_N PF15492.1 EMC97964.1 - 4.6e-05 22.6 0.1 0.0092 15.1 0.0 2.3 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Lactonase PF10282.4 EMC97964.1 - 0.0063 15.6 0.0 1.6 7.6 0.1 3.0 3 1 0 3 3 3 2 Lactonase, 7-bladed beta-propeller zf-C2H2_4 PF13894.1 EMC97965.1 - 2.8e-08 33.5 25.5 0.16 12.3 0.3 6.7 7 0 0 7 7 6 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC97965.1 - 1.5e-07 31.3 21.9 0.23 11.8 0.1 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMC97965.1 - 0.00097 18.9 17.1 0.21 11.5 0.0 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.7 EMC97965.1 - 0.022 14.8 16.3 0.027 14.5 2.6 3.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 EMC97965.1 - 0.039 12.4 1.0 5.9 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF629) DZR PF12773.2 EMC97965.1 - 0.54 10.1 9.8 51 3.8 0.0 3.6 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.3 EMC97965.1 - 0.58 10.3 0.1 0.58 10.3 0.1 4.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC97965.1 - 1.9 8.6 20.1 0.22 11.6 0.3 4.1 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 EMC97965.1 - 2 8.0 5.3 1.8 8.2 0.0 2.6 2 1 0 2 2 2 0 GAGA factor zf-met PF12874.2 EMC97965.1 - 2.6 8.4 18.6 4.7 7.5 0.1 5.0 6 0 0 6 6 5 0 Zinc-finger of C2H2 type DUF983 PF06170.7 EMC97965.1 - 3.7 7.7 4.9 7.5 6.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Cyanate_lyase PF02560.9 EMC97967.1 - 2.7e-31 106.9 0.1 3.6e-31 106.4 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 EMC97967.1 - 0.006 16.3 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EMC97967.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Atg14 PF10186.4 EMC97968.1 - 1.9e-19 69.7 2.1 3.9e-19 68.7 1.4 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EMC97968.1 - 5.9e-05 22.2 0.9 0.00013 21.1 0.6 1.5 1 1 0 1 1 1 1 Autophagy protein Apg6 CHZ PF09649.5 EMC97968.1 - 0.16 11.2 1.9 2.4 7.4 0.5 2.6 2 0 0 2 2 2 0 Histone chaperone domain CHZ Borrelia_P83 PF05262.6 EMC97968.1 - 4.3 5.4 10.8 6.4 4.9 7.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mhr1 PF12829.2 EMC97969.1 - 2.6e-24 84.8 0.0 6e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Rep_fac-A_3 PF08661.6 EMC97970.1 - 1.2e-25 89.5 0.1 1.3e-25 89.3 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF1308 PF07000.6 EMC97971.1 - 3.3e-69 233.2 0.0 5.2e-68 229.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1308) SRP9-21 PF05486.7 EMC97972.1 - 4.6e-24 83.9 0.0 7e-24 83.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Fungal_trans PF04082.13 EMC97973.1 - 2.2e-18 66.0 0.5 4.5e-18 65.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EMC97973.1 - 4.5e-10 39.2 12.6 0.00013 22.1 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC97973.1 - 6.1e-06 26.2 7.4 6.1e-06 26.2 5.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC97973.1 - 0.004 17.3 18.1 0.077 13.3 1.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC97973.1 - 1 9.5 3.1 0.56 10.4 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC97973.1 - 2.5 8.1 6.8 2.3 8.2 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger GATase_4 PF13230.1 EMC97974.1 - 7.4e-13 47.8 0.0 3.2e-10 39.1 0.0 3.1 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMC97974.1 - 1.1e-08 35.0 0.0 1.6e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMC97974.1 - 8.5e-05 21.4 0.0 0.00028 19.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Cellulase PF00150.13 EMC97975.1 - 2.2e-36 125.5 0.9 3e-36 125.0 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF295 PF03478.13 EMC97975.1 - 0.13 11.5 0.2 0.82 9.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF295) RyR PF02026.11 EMC97976.1 - 1.6e-07 31.2 0.2 5.2e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 RyR domain AAA_17 PF13207.1 EMC97976.1 - 0.00015 22.6 0.0 0.00063 20.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMC97976.1 - 0.021 15.0 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMC97976.1 - 0.023 14.4 0.1 0.08 12.7 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EMC97976.1 - 0.026 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EMC97976.1 - 0.033 14.4 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMC97976.1 - 0.13 12.0 0.0 0.43 10.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KxDL PF10241.4 EMC97977.1 - 0.0013 18.5 1.2 0.0031 17.3 0.0 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein CorA PF01544.13 EMC97977.1 - 0.0023 17.0 3.3 0.0023 17.0 2.3 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF4200 PF13863.1 EMC97977.1 - 0.81 9.6 9.2 0.86 9.5 4.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AMP-binding PF00501.23 EMC97978.1 - 9.3e-84 281.2 0.0 1.2e-83 280.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC97978.1 - 2.7e-14 53.8 0.1 5.9e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EMC97979.1 - 1e-35 123.0 31.0 1e-35 123.0 21.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC97979.1 - 9.9e-12 44.1 5.7 9.9e-12 44.1 4.0 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter PEP_mutase PF13714.1 EMC97980.1 - 9.9e-46 155.8 1.1 1.1e-45 155.6 0.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMC97980.1 - 5.9e-19 67.6 0.9 7.5e-19 67.3 0.7 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DnaJ PF00226.26 EMC97981.1 - 4.2e-15 55.2 0.6 9.3e-15 54.1 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain HET PF06985.6 EMC97981.1 - 4.3e-14 52.8 2.6 8.3e-14 51.9 0.0 2.7 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) DUF1772 PF08592.6 EMC97982.1 - 1.1e-12 47.8 3.2 6.1e-09 35.7 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) Gemini_C4 PF01492.12 EMC97982.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Geminivirus C4 protein BetaGal_dom4_5 PF13364.1 EMC97982.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain AMP-binding PF00501.23 EMC97983.1 - 9.4e-40 136.2 0.0 1.3e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC97983.1 - 6.8e-05 23.7 0.0 0.00018 22.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TIM PF00121.13 EMC97984.1 - 3.2e-88 294.9 0.2 3.6e-88 294.7 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Aminotran_1_2 PF00155.16 EMC97986.1 - 2.6e-57 194.4 0.0 3.4e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMC97986.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Arylsulfotran_2 PF14269.1 EMC97987.1 - 1.7e-42 145.6 0.0 2.4e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMC97987.1 - 7.3e-09 34.6 0.7 8.9e-08 31.0 0.5 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) HAD_2 PF13419.1 EMC97988.1 - 3.8e-18 66.3 0.0 6.3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC97988.1 - 1.1e-07 32.4 0.0 5.6e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC97988.1 - 7.5e-07 28.7 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EMC97988.1 - 0.006 16.7 0.0 0.0087 16.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EMC97988.1 - 0.044 13.1 0.8 4.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Attachment_P66 PF11263.3 EMC97988.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 UCR_hinge PF02320.11 EMC97988.1 - 0.2 11.6 0.2 0.2 11.6 0.1 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein DUF1989 PF09347.5 EMC97989.1 - 1.6e-42 144.7 0.0 5.4e-32 110.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1989) CDC45 PF02724.9 EMC97989.1 - 3 5.7 8.4 4.4 5.2 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Lipase_GDSL_2 PF13472.1 EMC97990.1 - 0.0001 22.5 0.0 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipocalin_5 PF13924.1 EMC97991.1 - 2.3e-32 111.6 0.0 2.6e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain K-cyclin_vir_C PF09080.5 EMC97992.1 - 0.032 14.4 0.1 0.032 14.4 0.1 1.1 1 0 0 1 1 1 0 K cyclin, C terminal MFS_1 PF07690.11 EMC97993.1 - 3.5e-30 104.8 36.9 2.2e-16 59.5 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC97993.1 - 1.4e-06 27.1 22.9 2.4e-06 26.4 15.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EMC97993.1 - 0.0027 17.4 4.3 0.45 10.3 0.2 2.7 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.15 EMC97993.1 - 0.015 13.3 5.1 1.5 6.7 0.1 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.11 EMC97993.1 - 0.76 9.2 11.8 1.9 7.9 1.2 2.9 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 MFS_2 PF13347.1 EMC97993.1 - 1.1 7.6 36.9 0.067 11.5 11.9 2.8 1 1 1 2 2 2 0 MFS/sugar transport protein Piwi PF02171.12 EMC97994.1 - 2.4e-76 256.5 0.0 3.2e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EMC97994.1 - 1.4e-14 53.1 0.0 5.2e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EMC97994.1 - 1.4e-13 50.3 0.0 2.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Complex1_LYR_2 PF13233.1 EMC97996.1 - 7.3e-19 68.1 0.0 9.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EMC97996.1 - 0.002 18.2 0.5 0.0047 17.1 0.3 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMC97996.1 - 0.0027 17.4 0.2 0.0048 16.6 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Hormone_3 PF00159.13 EMC97996.1 - 2.3 8.2 6.6 0.53 10.3 1.3 2.4 2 2 2 4 4 4 0 Pancreatic hormone peptide MMR_HSR1 PF01926.18 EMC97997.1 - 5.1e-20 71.5 0.0 8.7e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC97997.1 - 1.7e-05 24.0 0.0 6.4e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMC97997.1 - 0.00012 21.5 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMC97997.1 - 0.00015 21.6 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EMC97997.1 - 0.00042 19.6 0.0 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.8 EMC97997.1 - 0.009 14.8 0.0 0.88 8.3 0.0 2.0 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EMC97997.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EMC97997.1 - 0.023 14.2 0.0 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 EMC97997.1 - 0.042 14.3 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 EMC97997.1 - 0.08 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EMC97997.1 - 0.14 11.1 0.0 0.53 9.2 0.0 1.8 2 0 0 2 2 2 0 Septin Glyco_hydro_2_N PF02837.13 EMC97998.1 - 7.1e-25 87.4 0.1 1.3e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMC97998.1 - 4.1e-11 42.3 0.0 8.3e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMC97998.1 - 1.2e-09 38.6 0.3 3.5e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Aldo_ket_red PF00248.16 EMC97999.1 - 3.1e-56 190.2 0.0 3.5e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RBD PF02196.10 EMC97999.1 - 0.083 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Raf-like Ras-binding domain SET PF00856.23 EMC98000.1 - 3.3e-05 24.2 0.0 0.0001 22.6 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF2076 PF09849.4 EMC98001.1 - 2.7e-09 37.4 7.4 3.1e-09 37.2 5.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EMC98001.1 - 0.003 17.4 1.8 0.0044 16.8 1.3 1.3 1 0 0 1 1 1 1 CHCH domain Gly-zipper_OmpA PF13436.1 EMC98001.1 - 0.011 15.4 4.6 0.011 15.4 3.2 1.8 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain TFIIA PF03153.8 EMC98001.1 - 0.86 9.4 4.3 1 9.1 3.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bindin PF02084.10 EMC98001.1 - 1.5 8.8 6.5 3.5 7.6 4.2 1.8 1 1 1 2 2 2 0 Bindin PAT1 PF09770.4 EMC98001.1 - 1.5 6.9 9.2 1.4 7.0 6.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleoporin_FG PF13634.1 EMC98001.1 - 2.6 8.3 19.3 4.4 7.5 13.3 1.4 1 1 0 1 1 1 0 Nucleoporin FG repeat region DUF605 PF04652.11 EMC98001.1 - 3 7.1 11.5 3.7 6.8 8.0 1.2 1 0 0 1 1 1 0 Vta1 like Septin PF00735.13 EMC98002.1 - 3.3e-31 108.3 0.0 5.1e-18 65.0 0.0 2.6 2 1 0 2 2 2 2 Septin FtsK_SpoIIIE PF01580.13 EMC98002.1 - 0.00067 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 EMC98002.1 - 0.0018 18.7 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC98002.1 - 0.0028 17.5 0.0 0.0062 16.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EMC98002.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EMC98002.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Nop14 PF04147.7 EMC98002.1 - 0.057 11.3 13.6 0.085 10.7 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.17 EMC98002.1 - 0.15 11.4 0.1 0.56 9.5 0.1 1.9 1 1 0 1 1 1 0 Ras family TFIIF_alpha PF05793.7 EMC98002.1 - 0.46 8.8 9.6 0.76 8.0 6.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 EMC98002.1 - 1.6 7.7 11.6 2.3 7.1 8.0 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 EMC98002.1 - 4.6 6.4 12.1 7 5.8 8.4 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EMC98002.1 - 4.8 5.5 11.4 9.1 4.6 7.9 1.3 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 EMC98002.1 - 7.5 6.0 10.9 13 5.2 7.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RRM_6 PF14259.1 EMC98003.1 - 5.5e-07 29.4 0.0 8.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC98003.1 - 0.00089 18.8 0.0 0.0033 17.0 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC98003.1 - 0.035 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLH PF01738.13 EMC98005.1 - 6.5e-28 97.4 0.0 7.3e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC98005.1 - 1.5e-08 34.5 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EMC98005.1 - 0.042 13.2 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) zf-RING_UBOX PF13445.1 EMC98007.1 - 0.034 13.8 0.9 0.081 12.6 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 EMC98007.1 - 0.056 13.2 2.7 0.15 11.9 1.9 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EMC98007.1 - 0.082 12.5 1.8 0.26 10.9 1.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OmpH PF03938.9 EMC98007.1 - 2.3 8.1 13.0 0.52 10.2 3.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ADH_N PF08240.7 EMC98009.1 - 4.2e-30 103.7 0.2 8.7e-30 102.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC98009.1 - 2.3e-22 78.9 0.9 2.6e-22 78.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC98009.1 - 0.0029 18.4 0.1 0.0054 17.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMC98009.1 - 0.087 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1967 PF09269.6 EMC98009.1 - 0.087 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Polyketide_cyc2 PF10604.4 EMC98010.1 - 2.3e-06 27.7 0.0 2.7e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.17 EMC98011.1 - 3.6e-60 203.8 0.0 4.4e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ECH PF00378.15 EMC98012.1 - 1e-32 113.2 0.0 1.2e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FSH1 PF03959.8 EMC98013.1 - 5.7e-57 192.5 0.0 7.8e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMC98013.1 - 5.2e-05 23.2 0.3 0.0054 16.6 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC98013.1 - 0.0007 18.8 0.0 0.0015 17.7 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC98013.1 - 0.03 14.0 0.2 0.078 12.7 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 EMC98013.1 - 0.032 13.4 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 EMC98013.1 - 0.055 12.8 1.1 2.5 7.4 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase WD40 PF00400.27 EMC98014.1 - 5.8e-25 86.2 21.7 2.8e-06 26.9 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMC98014.1 - 1.5e-05 23.4 0.4 0.015 13.6 0.0 3.9 4 0 0 4 4 4 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 EMC98014.1 - 0.00066 19.8 0.6 0.74 10.1 0.0 3.5 4 0 0 4 4 4 2 PQQ-like domain PD40 PF07676.7 EMC98014.1 - 0.0098 15.5 0.1 0.042 13.5 0.0 2.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat SecE PF00584.15 EMC98015.1 - 1.3e-13 50.3 0.0 1.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TAT_signal PF10518.4 EMC98015.1 - 0.1 12.6 0.1 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Sec20 PF03908.8 EMC98015.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Sec20 NCD1 PF04904.8 EMC98015.1 - 0.14 11.9 0.0 1.2 8.9 0.0 1.9 1 1 1 2 2 2 0 NAB conserved region 1 (NCD1) GPI2 PF06432.6 EMC98017.1 - 1.9e-117 391.5 1.3 2.3e-117 391.3 0.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3301 PF11743.3 EMC98017.1 - 0.13 11.8 0.1 8 6.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) ADH_N PF08240.7 EMC98018.1 - 2e-16 59.7 0.5 3.4e-16 58.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC98018.1 - 6.8e-11 41.8 0.1 1.6e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMC98018.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMC98018.1 - 0.017 14.6 0.1 0.034 13.6 0.1 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EMC98018.1 - 0.17 11.2 0.7 0.96 8.8 0.3 2.2 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Mor PF08765.6 EMC98019.1 - 0.034 13.9 0.0 0.088 12.5 0.0 1.7 1 1 0 1 1 1 0 Mor transcription activator family TMEM154 PF15102.1 EMC98020.1 - 0.082 12.6 0.7 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family hEGF PF12661.2 EMC98020.1 - 0.85 9.8 7.7 0.078 13.0 1.9 2.0 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.8 EMC98020.1 - 3.7 7.8 11.2 7.5 6.8 7.8 1.5 1 0 0 1 1 1 0 EGF-like domain Ribosomal_S27e PF01667.12 EMC98021.1 - 4.2e-29 99.8 6.7 5.2e-29 99.5 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EMC98021.1 - 0.011 15.5 1.4 0.013 15.3 0.9 1.2 1 0 0 1 1 1 0 IBR domain zf-CSL PF05207.8 EMC98021.1 - 0.045 13.2 0.7 0.083 12.4 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger DeoC PF01791.4 EMC98022.1 - 1.8e-39 135.4 2.7 2.3e-39 135.0 1.9 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EMC98022.1 - 0.0013 17.7 0.1 0.0019 17.1 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EMC98022.1 - 0.076 12.2 0.1 0.17 11.1 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 EMC98022.1 - 0.077 11.8 0.3 0.11 11.3 0.2 1.4 1 1 0 1 1 1 0 FMN-dependent dehydrogenase adh_short_C2 PF13561.1 EMC98023.1 - 3.2e-30 105.6 0.0 3.8e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC98023.1 - 2e-26 92.8 0.0 2.6e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC98023.1 - 1e-07 31.8 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC98023.1 - 0.00034 20.6 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EMC98023.1 - 0.015 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMC98023.1 - 0.026 13.2 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1652 PF07865.6 EMC98023.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Tox-REase-2 PF15646.1 EMC98023.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 Peptidase_C65 PF10275.4 EMC98024.1 - 3e-62 210.1 0.0 3.9e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain PROL5-SMR PF15621.1 EMC98025.1 - 0.032 14.6 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family PCI PF01399.22 EMC98026.1 - 1.7e-19 70.0 0.4 3.9e-19 68.9 0.1 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EMC98026.1 - 2.5e-10 40.2 0.1 6.5e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Cas_DxTHG PF09455.5 EMC98026.1 - 0.0017 17.5 1.8 0.003 16.7 1.2 1.3 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family TPR_7 PF13176.1 EMC98026.1 - 0.021 14.5 1.4 15 5.7 0.0 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC98026.1 - 0.59 10.0 4.5 1.7 8.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC98026.1 - 2 8.5 8.0 2.8 8.0 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat CWC25 PF12542.3 EMC98027.1 - 1.4e-20 73.5 0.0 1.4e-20 73.5 0.0 3.8 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EMC98027.1 - 4.6e-12 45.7 5.5 4.6e-12 45.7 3.8 4.6 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.17 EMC98028.1 - 5.1e-54 182.0 0.0 5.9e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC98028.1 - 2.2e-15 57.1 0.0 3.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC98028.1 - 2.5e-09 36.6 0.0 3.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC98028.1 - 9.7e-05 21.6 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMC98028.1 - 0.00094 18.4 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC98028.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EMC98028.1 - 0.029 13.0 0.0 0.067 11.8 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 EMC98028.1 - 0.057 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EMC98028.1 - 0.078 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Annexin PF00191.15 EMC98029.1 - 1e-24 86.1 1.7 2.3e-05 24.1 0.1 4.6 4 1 0 4 4 4 4 Annexin Methyltransf_18 PF12847.2 EMC98031.1 - 3.7e-10 40.3 0.0 5.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC98031.1 - 1.5e-08 35.0 0.0 2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC98031.1 - 1.5e-08 34.9 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC98031.1 - 1.9e-08 34.1 0.0 2.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC98031.1 - 2.8e-08 33.4 0.0 3.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC98031.1 - 5e-08 32.5 0.0 9.7e-08 31.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EMC98031.1 - 1e-06 29.1 0.0 1.5e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC98031.1 - 1.1e-06 28.6 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC98031.1 - 0.0014 17.6 0.0 0.0036 16.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EMC98031.1 - 0.02 14.0 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FmrO PF07091.6 EMC98031.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DNA_pol_B PF00136.16 EMC98032.1 - 4.5e-94 315.8 0.0 8.7e-94 314.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EMC98032.1 - 6.3e-22 77.8 0.0 1e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EMC98032.1 - 5.5e-17 61.5 5.3 5.5e-17 61.5 3.7 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Methyltransf_21 PF05050.7 EMC98032.1 - 0.069 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase FkbM domain dsDNA_bind PF01984.15 EMC98033.1 - 3.6e-32 110.5 13.7 4.5e-32 110.2 9.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain CD99L2 PF12301.3 EMC98033.1 - 5.7e-05 22.8 5.1 0.072 12.7 0.1 2.1 2 0 0 2 2 2 2 CD99 antigen like protein 2 SDA1 PF05285.7 EMC98033.1 - 5.1 6.2 12.8 0.019 14.2 1.0 1.9 1 1 1 2 2 2 0 SDA1 PAPS_reduct PF01507.14 EMC98035.1 - 7.8e-44 149.5 0.0 1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.12 EMC98036.1 - 2.4e-87 291.7 0.0 3.4e-87 291.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EMC98036.1 - 4.3e-56 188.9 0.0 6.7e-56 188.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EMC98036.1 - 1.2e-52 177.5 0.0 2.1e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain SET PF00856.23 EMC98037.1 - 2.8e-09 37.4 0.0 1.4e-08 35.2 0.0 2.0 1 1 0 1 1 1 1 SET domain Sas10_Utp3 PF04000.10 EMC98038.1 - 3.2e-17 62.4 0.5 3.2e-17 62.4 0.4 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Ras PF00071.17 EMC98039.1 - 1.2e-54 184.0 0.0 1.4e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC98039.1 - 2.2e-17 63.6 0.0 3.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC98039.1 - 1.9e-07 30.4 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC98039.1 - 0.00079 18.9 0.0 0.0028 17.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TFIIH_BTF_p62_N PF08567.6 EMC98040.1 - 8.2e-21 73.4 0.0 1.9e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 EMC98040.1 - 2.3e-14 52.8 2.8 7.7e-07 28.7 0.0 2.9 2 0 0 2 2 2 2 BSD domain PH PF00169.24 EMC98040.1 - 0.012 15.8 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Mnd1 PF03962.10 EMC98040.1 - 0.27 10.8 2.9 0.69 9.5 0.1 2.4 2 0 0 2 2 2 0 Mnd1 family GDPD PF03009.12 EMC98041.1 - 2.3e-53 181.3 0.0 3.4e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.1 EMC98041.1 - 7.4e-05 23.1 0.1 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC98041.1 - 0.019 15.3 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.2 EMC98042.1 - 2.6e-10 40.5 0.0 2e-07 31.2 0.0 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC98042.1 - 1.8e-08 33.7 0.0 0.002 17.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EMC98042.1 - 1.7e-06 28.0 0.1 0.02 15.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC98042.1 - 4.3e-06 27.1 0.1 0.49 10.9 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC98042.1 - 5.4e-06 26.1 0.0 0.18 12.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat FTA4 PF13093.1 EMC98042.1 - 0.09 12.2 0.6 0.15 11.4 0.2 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ENTH PF01417.15 EMC98043.1 - 2.3e-46 156.7 0.0 3.8e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EMC98043.1 - 0.0028 16.4 0.0 0.004 15.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 EMC98043.1 - 0.01 15.1 0.2 0.02 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DUF1720 PF08226.6 EMC98043.1 - 0.013 15.5 43.2 0.013 15.5 29.9 5.0 2 2 3 5 5 5 0 Domain of unknown function (DUF1720) UIM PF02809.15 EMC98043.1 - 0.037 13.6 5.6 0.045 13.3 0.6 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif VHS PF00790.14 EMC98043.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain Ribosomal_S7 PF00177.16 EMC98044.1 - 5.4e-26 90.9 0.0 9.1e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Coq4 PF05019.8 EMC98047.1 - 1.3e-94 315.2 0.0 1.6e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ApbA_C PF08546.6 EMC98048.1 - 4.4e-32 110.7 0.6 9.3e-32 109.6 0.4 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMC98048.1 - 7.7e-25 87.0 0.1 8.2e-18 64.2 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA DUF1571 PF07608.6 EMC98048.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) Arb2 PF09757.4 EMC98049.1 - 4.1e-13 49.1 0.0 5.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Ribosomal_S14 PF00253.16 EMC98050.1 - 4.8e-18 64.2 0.6 2e-17 62.3 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e GFO_IDH_MocA PF01408.17 EMC98052.1 - 2.7e-16 60.1 0.0 4.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMC98052.1 - 2.5e-06 27.2 0.0 5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EMC98052.1 - 0.091 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_C97 PF05903.9 EMC98053.1 - 1.1e-36 125.8 0.0 2.1e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EMC98053.1 - 1.4e-28 99.4 0.0 2e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EMC98053.1 - 1.3e-17 63.3 0.0 4.1e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin DUF2847 PF11009.3 EMC98053.1 - 0.00046 19.7 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_2 PF13098.1 EMC98053.1 - 0.00092 19.3 0.2 0.0049 17.0 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EMC98053.1 - 0.0043 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain T4_deiodinase PF00837.12 EMC98053.1 - 0.0059 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Iodothyronine deiodinase Thioredoxin_8 PF13905.1 EMC98053.1 - 0.008 16.2 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EMC98053.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 EMC98053.1 - 0.037 13.7 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DIM1 PF02966.11 EMC98053.1 - 0.068 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Glutaredoxin PF00462.19 EMC98053.1 - 0.082 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin TraF PF13728.1 EMC98053.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein GDA1_CD39 PF01150.12 EMC98054.1 - 2e-96 323.1 0.0 2.6e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GCV_T PF01571.16 EMC98055.1 - 1e-13 51.1 0.1 5.2e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EMC98055.1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DCP2 PF05026.8 EMC98056.1 - 3.5e-31 106.9 0.3 1e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 EMC98056.1 - 7.1e-17 61.3 0.1 2.2e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain DUF2277 PF10041.4 EMC98056.1 - 0.075 13.0 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) DnaJ PF00226.26 EMC98057.1 - 5.6e-19 67.6 0.4 1.2e-18 66.5 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Pro-kuma_activ PF09286.6 EMC98058.1 - 1.2e-39 135.5 0.1 2.8e-39 134.4 0.2 1.5 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMC98058.1 - 1.5e-10 40.7 1.1 3.1e-10 39.6 0.8 1.6 1 0 0 1 1 1 1 Subtilase family DUF3429 PF11911.3 EMC98059.1 - 2.8e-37 127.8 7.6 4e-37 127.3 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Apc9 PF12856.2 EMC98059.1 - 0.11 12.5 0.8 0.21 11.6 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 DUF1162 PF06650.7 EMC98060.1 - 1.3e-87 293.5 0.0 1.3e-85 286.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EMC98060.1 - 1.7e-40 137.2 0.4 6.2e-40 135.4 0.3 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EMC98060.1 - 1.7e-05 24.8 2.7 4.5e-05 23.5 0.0 3.0 3 1 0 3 3 3 1 ATG C terminal domain Complex1_51K PF01512.12 EMC98063.1 - 3.5e-47 159.9 0.0 5.8e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EMC98063.1 - 1e-17 63.0 0.6 2e-17 62.0 0.4 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EMC98063.1 - 9.9e-09 34.9 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 SLBB domain Cyclase PF04199.8 EMC98064.1 - 1.5e-13 50.8 0.5 3.1e-13 49.7 0.3 1.4 1 1 0 1 1 1 1 Putative cyclase Cytotoxic PF09000.5 EMC98064.1 - 0.063 13.3 0.1 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Cytotoxic ECH PF00378.15 EMC98065.1 - 3.2e-20 72.3 0.0 3.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EMC98065.1 - 0.07 12.9 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 RasGEF PF00617.14 EMC98066.1 - 1.3e-62 210.9 0.2 2.5e-62 209.9 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMC98066.1 - 4.2e-25 87.8 0.1 8.6e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EMC98066.1 - 2.8e-14 52.1 0.1 6.4e-14 51.0 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC98066.1 - 4.3e-14 51.8 0.2 9e-14 50.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC98066.1 - 1.3e-11 43.7 0.0 2.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EMC98066.1 - 3.6e-05 23.5 0.0 7.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 WW domain Fungal_trans PF04082.13 EMC98069.1 - 4.4e-16 58.5 4.0 7.5e-16 57.7 2.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EMC98069.1 - 5.2e-08 32.8 14.7 2.3e-05 24.4 4.6 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC98069.1 - 5.3e-06 26.3 13.4 0.0028 17.8 3.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC98069.1 - 2.8e-05 24.2 14.9 0.01 16.1 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type PyrI_C PF02748.10 EMC98069.1 - 0.1 12.0 2.4 0.092 12.1 0.5 1.8 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain AMP-binding PF00501.23 EMC98070.1 - 7.3e-50 169.5 0.1 9.5e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC98070.1 - 0.023 15.6 0.0 0.069 14.1 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AA_permease_2 PF13520.1 EMC98071.1 - 4.6e-50 170.3 56.0 5.7e-50 170.0 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC98071.1 - 9.3e-14 50.6 48.9 1.3e-13 50.1 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4234 PF14018.1 EMC98071.1 - 0.00057 19.5 0.6 0.00057 19.5 0.4 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF4234) TauD PF02668.11 EMC98072.1 - 1.1e-45 156.3 0.8 1.3e-45 156.0 0.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family YcgL PF05166.8 EMC98072.1 - 0.13 12.3 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 YcgL domain Thioredoxin PF00085.15 EMC98075.1 - 1.2e-59 198.4 0.1 6.2e-29 99.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EMC98075.1 - 3.7e-20 72.3 0.1 1.6e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EMC98075.1 - 4.1e-18 65.6 0.1 3.8e-08 33.5 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC98075.1 - 1.9e-12 47.0 0.0 6e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EMC98075.1 - 8e-12 45.1 0.0 3.7e-05 23.7 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EMC98075.1 - 5.1e-08 32.6 0.1 0.01 15.4 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 EMC98075.1 - 5.9e-06 26.2 0.0 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 EMC98075.1 - 1.4e-05 24.9 1.7 0.49 10.1 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 EMC98075.1 - 2.7e-05 23.7 1.0 0.04 13.4 0.1 2.4 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EMC98075.1 - 0.00022 20.7 0.3 0.13 11.8 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 EMC98075.1 - 0.00033 20.3 0.0 0.17 11.7 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EMC98075.1 - 0.00083 19.4 3.7 2 8.4 0.1 4.0 3 2 2 5 5 5 2 Thioredoxin Glutaredoxin PF00462.19 EMC98075.1 - 0.0072 16.2 1.1 3.5 7.7 0.0 3.5 3 1 0 3 3 3 1 Glutaredoxin TraF PF13728.1 EMC98075.1 - 0.0088 15.5 0.0 0.47 9.9 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein DDE_Tnp_1_2 PF13586.1 EMC98075.1 - 0.017 15.3 0.0 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain GAS PF13851.1 EMC98075.1 - 0.042 13.0 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HyaE PF07449.6 EMC98075.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE OHCU_decarbox PF09349.5 EMC98078.1 - 1.9e-43 148.5 0.5 2.1e-43 148.3 0.3 1.0 1 0 0 1 1 1 1 OHCU decarboxylase CHAT PF12770.2 EMC98078.1 - 0.0033 16.6 0.2 0.0038 16.3 0.1 1.1 1 0 0 1 1 1 1 CHAT domain S6PP PF05116.8 EMC98078.1 - 0.0059 15.9 0.1 0.0083 15.4 0.1 1.5 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase FGGY_C PF02782.11 EMC98078.1 - 0.07 12.7 0.1 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Myb_DNA-bind_3 PF12776.2 EMC98079.1 - 0.072 13.7 0.9 0.15 12.7 0.7 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MAP65_ASE1 PF03999.7 EMC98081.1 - 3.4e-71 240.6 8.5 3.4e-71 240.6 5.9 2.4 2 1 1 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.6 EMC98081.1 - 0.027 12.0 1.5 1.1 6.7 0.0 2.3 2 1 0 2 2 2 0 Prominin Spectrin PF00435.16 EMC98081.1 - 0.84 9.9 15.4 2.9 8.2 3.1 3.7 3 2 0 3 3 3 0 Spectrin repeat Ndc1_Nup PF09531.5 EMC98081.1 - 4.3 5.6 6.1 10 4.4 4.2 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF680 PF05079.7 EMC98081.1 - 5.6 7.5 7.7 16 6.0 1.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF680) DUF533 PF04391.7 EMC98082.1 - 0.079 12.3 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Rick_17kDa_Anti PF05433.10 EMC98082.1 - 0.85 9.3 8.6 0.23 11.1 0.8 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 EMC98082.1 - 7.3 6.8 10.2 13 5.9 1.9 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide RRM_6 PF14259.1 EMC98083.1 - 4.2e-11 42.6 0.0 7.8e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC98083.1 - 5.5e-09 35.5 0.0 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC98083.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G0-G1_switch_2 PF15103.1 EMC98083.1 - 4 7.7 4.9 9.4 6.5 3.0 1.9 1 1 0 1 1 1 0 G0/G1 switch protein 2 UreD PF01774.12 EMC98084.1 - 5.1e-50 169.8 0.0 6.3e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 EMC98085.1 - 3.4e-29 100.9 0.0 1.4e-28 98.9 0.0 2.1 1 0 0 1 1 1 1 STAG domain Rota_NSP4 PF01452.11 EMC98085.1 - 0.044 13.1 0.0 1.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Rotavirus non structural protein PTCB-BRCT PF12738.2 EMC98086.1 - 5.2e-44 147.9 1.9 6e-20 70.8 0.0 4.3 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 EMC98086.1 - 3e-32 110.5 0.0 1.9e-12 47.1 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Neisseria_TspB PF05616.8 EMC98086.1 - 0.33 9.2 9.8 0.58 8.4 6.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Arrestin_C PF02752.17 EMC98087.1 - 2.1e-23 82.9 0.0 6.7e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMC98087.1 - 1.1e-09 38.3 0.0 3e-06 27.1 0.0 2.6 1 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF3643 PF12356.3 EMC98088.1 - 0.13 11.6 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3643) Pro_isomerase PF00160.16 EMC98090.1 - 1.1e-45 155.6 0.0 1.9e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EMC98090.1 - 6.4e-06 25.5 2.6 6.4e-06 25.5 1.8 2.1 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EMC98090.1 - 2.8e-05 24.0 0.0 0.00011 22.0 0.0 2.0 1 1 1 2 2 2 1 U-box domain Pentapeptide_4 PF13599.1 EMC98091.1 - 1.6e-05 24.6 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF2080 PF09853.4 EMC98091.1 - 0.022 14.5 9.3 48 3.7 0.0 5.7 1 1 5 6 6 6 0 Putative transposon-encoded protein (DUF2080) Crp PF00325.15 EMC98091.1 - 0.027 13.9 15.1 31 4.1 0.0 5.9 2 2 4 6 6 6 0 Bacterial regulatory proteins, crp family His_Phos_1 PF00300.17 EMC98092.1 - 9.3e-29 100.5 0.0 1.1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CYTH PF01928.16 EMC98092.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 CYTH domain VSG_B PF13206.1 EMC98093.1 - 0.44 9.6 4.2 0.64 9.0 2.9 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Tom22 PF04281.8 EMC98094.1 - 2.1e-47 160.0 1.6 2.4e-47 159.8 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 PQ-loop PF04193.9 EMC98095.1 - 1e-33 114.6 9.2 8.7e-17 60.4 0.3 2.4 2 0 0 2 2 2 2 PQ loop repeat Abhydrolase_5 PF12695.2 EMC98096.1 - 1.4e-06 28.1 0.3 9.5e-06 25.4 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC98096.1 - 1.5e-05 25.0 0.2 0.00042 20.2 0.0 2.4 2 1 0 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMC98096.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EMC98096.1 - 0.00014 21.4 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 EMC98096.1 - 0.0099 14.9 0.0 3.2 6.7 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 EMC98096.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EMC98096.1 - 0.059 13.5 0.0 0.68 10.1 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain LCAT PF02450.10 EMC98096.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EMC98096.1 - 0.08 12.5 0.3 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Dynamin_N PF00350.18 EMC98097.1 - 2.3e-16 60.0 0.0 2.3e-16 60.0 0.0 2.5 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EMC98097.1 - 4.2e-09 36.3 0.0 2e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC98097.1 - 9.3e-07 28.4 0.5 1.6e-05 24.4 0.3 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.4 EMC98097.1 - 0.00012 21.5 1.7 0.00012 21.5 1.2 2.3 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Miro PF08477.8 EMC98097.1 - 0.023 15.1 0.1 0.62 10.5 0.1 2.9 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EMC98097.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HRXXH PF13933.1 EMC98097.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase family Toxin_47 PF15527.1 EMC98097.1 - 0.096 12.4 0.5 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative toxin 47 AAA_17 PF13207.1 EMC98097.1 - 0.14 13.0 0.1 0.92 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Tweety PF04906.8 EMC98097.1 - 1 7.7 4.0 2 6.7 0.3 2.2 2 0 0 2 2 2 0 Tweety Snf7 PF03357.16 EMC98098.1 - 5.6e-38 130.0 20.4 9.3e-38 129.2 14.2 1.3 1 0 0 1 1 1 1 Snf7 V_ATPase_I PF01496.14 EMC98098.1 - 0.058 11.2 4.9 0.068 11.0 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1188 PF06690.6 EMC98098.1 - 0.071 12.2 0.1 0.14 11.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1188) YlqD PF11068.3 EMC98098.1 - 0.094 12.7 23.0 2.8 7.9 4.8 2.1 1 1 1 2 2 2 0 YlqD protein Ist1 PF03398.9 EMC98098.1 - 0.24 10.7 6.3 0.4 10.0 4.4 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PMC2NT PF08066.7 EMC98098.1 - 0.77 10.1 4.5 1.1 9.6 0.5 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Remorin_C PF03763.8 EMC98098.1 - 2.3 7.7 9.8 3.3 7.2 6.2 1.7 1 1 0 1 1 1 0 Remorin, C-terminal region Pox_A_type_inc PF04508.7 EMC98098.1 - 7.4 6.6 9.1 0.81 9.6 2.7 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Hom_end_hint PF05203.11 EMC98098.1 - 9.6 5.8 7.1 22 4.6 4.7 1.7 1 1 1 2 2 2 0 Hom_end-associated Hint TPR_MLP1_2 PF07926.7 EMC98098.1 - 9.7 5.9 14.2 20 4.9 9.8 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Chromate_transp PF02417.10 EMC98099.1 - 1.2e-52 177.9 34.7 6.3e-29 100.7 10.3 2.4 2 0 0 2 2 2 2 Chromate transporter DUF3353 PF11833.3 EMC98099.1 - 0.85 9.0 3.4 1.3 8.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) PP2C PF00481.16 EMC98100.1 - 3.9e-64 216.5 0.1 8e-52 176.1 0.1 3.2 1 1 2 3 3 3 3 Protein phosphatase 2C CBS PF00571.23 EMC98101.1 - 9e-26 89.3 8.1 2.2e-10 40.1 0.0 4.2 4 0 0 4 4 4 4 CBS domain GDPD PF03009.12 EMC98102.1 - 3e-13 49.8 0.0 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family FmrO PF07091.6 EMC98103.1 - 0.0059 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) COesterase PF00135.23 EMC98104.1 - 1.7e-70 238.2 0.0 2.3e-40 138.8 0.0 2.4 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC98104.1 - 0.0054 16.3 0.2 0.015 14.8 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Prp19_bind PF06991.6 EMC98105.1 - 4.3e-45 154.1 21.2 4.3e-45 154.1 14.7 1.7 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain Lactamase_B_3 PF13483.1 EMC98106.1 - 0.044 13.4 0.5 0.45 10.1 0.0 2.7 3 0 0 3 3 3 0 Beta-lactamase superfamily domain SNF2_N PF00176.18 EMC98107.1 - 3.9e-72 242.5 0.0 6.6e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EMC98107.1 - 3.1e-18 65.6 0.0 6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EMC98107.1 - 2e-13 49.9 0.0 5.8e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EMC98107.1 - 1.3e-07 31.5 7.9 2.5e-07 30.5 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EMC98107.1 - 1.8e-06 27.5 0.0 4.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EMC98107.1 - 4.1e-05 23.1 8.2 7.9e-05 22.2 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC98107.1 - 0.00021 20.9 6.0 0.00039 20.0 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC98107.1 - 0.00031 20.5 7.6 0.00061 19.5 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMC98107.1 - 0.015 15.0 6.5 0.046 13.4 4.6 1.8 1 1 0 1 1 1 0 zinc-RING finger domain UBA_4 PF14555.1 EMC98107.1 - 0.051 13.1 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain zf-C3HC4_4 PF15227.1 EMC98107.1 - 7.3 6.5 7.6 17 5.4 5.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.14 EMC98108.1 - 2e-47 161.7 0.1 2.7e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3526 PF12040.3 EMC98108.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) Sugar_tr PF00083.19 EMC98111.1 - 2.1e-76 257.3 18.3 2.4e-76 257.1 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC98111.1 - 2e-24 85.9 22.2 3.5e-22 78.5 8.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COesterase PF00135.23 EMC98112.1 - 4.1e-79 266.6 0.1 5e-79 266.4 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC98112.1 - 1.9e-08 34.1 0.2 2e-07 30.8 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC98112.1 - 0.073 12.2 0.2 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1992 PF09350.5 EMC98113.1 - 1.6e-24 85.4 0.1 4e-24 84.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF664 PF04978.7 EMC98115.1 - 0.035 14.3 0.4 0.056 13.6 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF664) NfI_DNAbd_pre-N PF10524.4 EMC98116.1 - 0.047 13.2 0.1 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Clathrin_H_link PF13838.1 EMC98119.1 - 0.066 13.1 0.4 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 Clathrin-H-link 2OG-FeII_Oxy PF03171.15 EMC98120.1 - 5.8e-13 48.9 0.0 1.7e-11 44.3 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2_5_RNA_ligase2 PF13563.1 EMC98123.1 - 1.3e-11 44.4 0.1 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.4 EMC98123.1 - 0.045 13.4 0.1 0.12 12.1 0.0 1.5 1 1 1 2 2 2 0 AKAP7 2'5' RNA ligase-like domain Abhydrolase_3 PF07859.8 EMC98124.1 - 2.9e-36 125.0 1.3 4.4e-36 124.4 0.9 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC98124.1 - 2.2e-07 30.7 0.9 7.6e-07 28.9 0.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 EMC98124.1 - 0.0023 16.7 0.0 0.003 16.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EMC98124.1 - 0.024 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2424 PF10340.4 EMC98124.1 - 0.082 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Titin_Z PF09042.6 EMC98124.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Titin Z MFS_1 PF07690.11 EMC98125.1 - 1e-35 123.0 26.5 1.4e-35 122.6 18.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EMC98125.1 - 0.0038 15.3 0.4 0.0086 14.1 0.3 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Microtub_assoc PF07989.6 EMC98126.1 - 0.026 14.3 5.5 0.11 12.2 3.8 2.1 1 1 0 1 1 1 0 Microtubule associated IncA PF04156.9 EMC98126.1 - 6.7 6.2 13.8 24 4.4 9.5 1.9 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EMC98126.1 - 6.8 5.6 7.6 15 4.5 5.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 adh_short_C2 PF13561.1 EMC98127.1 - 1.5e-34 119.8 0.0 2.4e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC98127.1 - 2.2e-27 96.0 0.5 3.1e-27 95.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC98127.1 - 9.8e-12 44.8 0.1 1.4e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC98127.1 - 0.023 14.1 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMC98127.1 - 0.023 14.4 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EMC98127.1 - 0.024 13.7 0.0 0.055 12.6 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Methyltransf_11 PF08241.7 EMC98128.1 - 1.6e-16 60.5 0.0 3.9e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC98128.1 - 1.6e-15 56.9 0.0 2.4e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC98128.1 - 3.7e-15 56.0 0.0 6.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMC98128.1 - 1.5e-11 43.8 0.0 2.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EMC98128.1 - 3.1e-10 40.5 0.0 2.6e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC98128.1 - 2e-08 34.4 0.0 4.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC98128.1 - 3.6e-08 32.8 0.0 5.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMC98128.1 - 3.8e-08 33.7 0.0 1.6e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC98128.1 - 2.4e-06 27.5 0.2 5.7e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.5 EMC98128.1 - 0.00018 21.3 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_15 PF09445.5 EMC98128.1 - 0.00082 18.9 0.0 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 EMC98128.1 - 0.00083 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EMC98128.1 - 0.0038 16.2 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EMC98128.1 - 0.0083 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EMC98128.1 - 0.064 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_9 PF08003.6 EMC98128.1 - 0.093 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) COX6A PF02046.10 EMC98129.1 - 2.9e-42 143.2 0.4 3.2e-42 143.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF3017 PF11222.3 EMC98129.1 - 2.3 8.0 4.0 1 9.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) F-box-like PF12937.2 EMC98130.1 - 7.4e-08 31.9 1.0 1.7e-07 30.8 0.4 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EMC98130.1 - 0.066 12.8 0.1 9 6.0 0.1 3.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.11 EMC98131.1 - 1.1e-30 106.5 41.7 7.4e-30 103.8 29.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily BTP PF05232.7 EMC98131.1 - 0.033 13.9 3.8 0.035 13.8 0.2 2.8 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family FMN_dh PF01070.13 EMC98132.1 - 1.2e-103 346.6 0.1 1.7e-103 346.1 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMC98132.1 - 1.6e-19 69.4 0.1 3.8e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThiG PF05690.9 EMC98132.1 - 5.7e-06 25.5 1.4 0.0024 16.9 0.0 3.1 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 EMC98132.1 - 0.00027 20.2 0.1 0.00042 19.5 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EMC98132.1 - 0.00097 18.1 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMC98132.1 - 0.0027 16.6 3.3 0.033 13.0 0.2 3.1 3 1 1 4 4 4 1 IMP dehydrogenase / GMP reductase domain Dus PF01207.12 EMC98132.1 - 0.01 14.6 0.0 0.022 13.5 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EMC98132.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI PFU PF09070.6 EMC98133.1 - 2.4e-05 24.3 0.1 5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BTB PF00651.26 EMC98134.1 - 8.7e-06 25.7 0.0 1.9e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_S4 PF00163.14 EMC98135.1 - 4.5e-30 103.8 2.1 9.1e-30 102.9 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EMC98135.1 - 9.1e-12 44.2 1.0 9.1e-12 44.2 0.7 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EMC98137.1 - 5.6e-41 138.3 3.2 5.6e-41 138.3 2.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Nexin_C PF08628.7 EMC98137.1 - 0.086 12.9 0.1 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Sorting nexin C terminal DUP PF00674.13 EMC98138.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 DUP family TFIIF_alpha PF05793.7 EMC98138.1 - 4.7 5.4 9.2 10 4.3 6.4 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) OPT PF03169.10 EMC98140.1 - 5e-91 306.0 44.7 5.8e-91 305.8 31.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein zf-C3HC4_2 PF13923.1 EMC98141.1 - 1.1e-07 31.6 7.6 1.9e-07 30.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC98141.1 - 1.2e-07 31.4 6.9 2.1e-07 30.6 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC98141.1 - 4.2e-07 29.5 5.9 7.4e-07 28.7 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC98141.1 - 6.3e-07 28.9 7.1 1.1e-06 28.2 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC98141.1 - 2.1e-06 27.3 6.1 3.9e-06 26.4 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC98141.1 - 6.1e-06 26.0 4.3 6.3e-05 22.7 3.4 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC98141.1 - 0.0015 18.2 2.2 0.0015 18.2 1.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger TerY-C PF15616.1 EMC98141.1 - 0.64 9.9 3.0 1.9 8.4 2.1 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain MFS_1 PF07690.11 EMC98142.1 - 4e-34 117.8 32.9 3.4e-33 114.8 20.3 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98142.1 - 6.6e-10 38.1 13.7 6.6e-10 38.1 9.5 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMC98142.1 - 0.00054 18.2 3.2 0.00094 17.4 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SID-1_RNA_chan PF13965.1 EMC98142.1 - 0.15 10.1 0.4 0.25 9.4 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RhoGAP PF00620.22 EMC98143.1 - 9.1e-41 138.9 0.0 2.7e-40 137.4 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EMC98143.1 - 1.2e-10 41.4 1.5 3.5e-10 39.9 0.3 2.2 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Rsm22 PF09243.5 EMC98144.1 - 3.7e-30 104.9 0.0 2.3e-21 76.0 0.0 3.1 3 1 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Pkinase PF00069.20 EMC98145.1 - 1.5e-38 132.4 0.0 1.9e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC98145.1 - 8.3e-14 51.2 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC98145.1 - 1.8e-05 24.6 0.0 0.0014 18.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMC98145.1 - 0.053 12.3 0.1 0.081 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DASH_Spc19 PF08287.6 EMC98147.1 - 6.1e-48 162.3 5.2 7.4e-48 162.0 3.6 1.1 1 0 0 1 1 1 1 Spc19 UPF0184 PF03670.8 EMC98147.1 - 0.1 12.8 0.6 0.19 11.9 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) COG5 PF10392.4 EMC98147.1 - 0.16 11.9 10.3 0.78 9.6 0.1 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 SH3_1 PF00018.23 EMC98149.1 - 1.3e-05 24.4 0.0 3.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC98149.1 - 0.0067 15.9 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-CCCH PF00642.19 EMC98150.1 - 3.1e-05 23.5 1.3 5.6e-05 22.7 0.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PMC2NT PF08066.7 EMC98150.1 - 0.024 14.9 0.8 0.062 13.6 0.3 1.9 1 1 0 1 1 1 0 PMC2NT (NUC016) domain Het-C PF07217.6 EMC98150.1 - 0.029 12.5 4.1 0.04 12.1 2.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Sec2p PF06428.6 EMC98150.1 - 0.044 13.6 0.8 0.044 13.6 0.6 3.1 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Prefoldin_3 PF13758.1 EMC98150.1 - 0.046 13.4 2.6 2.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit AAA_13 PF13166.1 EMC98150.1 - 0.05 12.0 6.2 0.075 11.4 4.3 1.3 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 EMC98150.1 - 0.062 11.9 6.8 0.097 11.3 4.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Spectrin PF00435.16 EMC98150.1 - 0.15 12.3 11.0 2 8.7 4.0 3.1 1 1 2 3 3 3 0 Spectrin repeat KxDL PF10241.4 EMC98150.1 - 0.19 11.6 4.4 0.085 12.7 1.2 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein ADIP PF11559.3 EMC98150.1 - 0.24 11.3 10.4 0.2 11.5 5.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EMC98150.1 - 0.39 9.8 5.3 1.1 8.3 3.6 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EMC98150.1 - 0.66 9.7 6.6 0.79 9.5 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3138 PF11336.3 EMC98150.1 - 0.72 7.9 5.1 0.95 7.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) APG6 PF04111.7 EMC98150.1 - 0.92 8.4 10.1 1.3 7.9 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Fez1 PF06818.10 EMC98150.1 - 1.1 9.2 11.2 1.6 8.7 7.1 1.6 1 1 0 1 1 1 0 Fez1 Phage_GP20 PF06810.6 EMC98150.1 - 1.2 8.5 9.4 1.4 8.3 3.6 2.5 1 1 2 3 3 3 0 Phage minor structural protein GP20 Nup54 PF13874.1 EMC98150.1 - 1.2 8.7 7.2 0.58 9.8 2.8 1.9 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 SlyX PF04102.7 EMC98150.1 - 1.2 9.5 11.8 20 5.6 2.1 4.1 3 1 1 4 4 4 0 SlyX Syntaxin PF00804.20 EMC98150.1 - 1.4 9.1 10.7 8.3 6.6 1.0 3.1 1 1 2 3 3 3 0 Syntaxin DivIC PF04977.10 EMC98150.1 - 1.5 8.3 12.7 0.28 10.7 1.1 3.3 2 1 1 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.14 EMC98150.1 - 1.7 6.3 4.9 2.2 6.0 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.8 EMC98150.1 - 1.9 9.2 4.2 6.6 7.5 0.4 2.6 1 1 1 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.7 EMC98150.1 - 4.5 7.1 7.8 0.53 10.1 2.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EMC98150.1 - 5.4 6.5 10.1 3.5 7.1 3.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 EMC98150.1 - 5.8 5.7 8.6 4.2 6.2 4.1 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EMC98150.1 - 7 6.9 9.1 28 5.0 3.7 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.6 EMC98150.1 - 8 5.6 10.0 2.5 7.3 2.7 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Ribonuc_red_sm PF00268.16 EMC98151.1 - 3e-118 393.9 1.8 3.6e-118 393.6 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain WD40 PF00400.27 EMC98152.1 - 6.4e-14 51.2 1.8 1.7e-11 43.5 0.1 4.2 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF4613 PF15390.1 EMC98152.1 - 0.012 13.8 0.0 0.043 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) DUF3312 PF11768.3 EMC98152.1 - 0.024 12.8 0.0 0.081 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EMC98152.1 - 0.052 11.8 0.0 3.9 5.6 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain Mito_carr PF00153.22 EMC98153.1 - 6e-58 192.5 1.1 1.1e-19 69.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1751 PF08551.5 EMC98154.1 - 0.00028 21.1 2.5 0.0004 20.6 0.6 2.1 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) SNARE PF05739.14 EMC98158.1 - 4.6e-17 61.4 1.0 4.6e-17 61.4 0.7 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EMC98158.1 - 1.4e-15 57.3 4.9 3e-15 56.2 0.1 2.8 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EMC98158.1 - 0.014 14.9 0.8 0.014 14.9 0.5 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 EMC98158.1 - 0.082 12.9 8.0 0.21 11.5 0.0 2.9 1 1 1 3 3 3 0 Zinc finger-containing protein Syntaxin-18_N PF10496.4 EMC98158.1 - 0.14 12.0 0.4 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Spc7 PF08317.6 EMC98158.1 - 0.72 8.4 5.1 0.88 8.1 0.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.7 EMC98158.1 - 8.3 6.8 7.5 1.9 8.9 0.2 3.2 3 0 0 3 3 3 0 SlyX Acatn PF13000.2 EMC98159.1 - 8.3e-147 490.0 21.4 7.1e-75 252.5 4.9 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Yae1_N PF09811.4 EMC98161.1 - 1.6e-12 46.6 4.2 2.8e-12 45.9 2.9 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal MFS_1 PF07690.11 EMC98162.1 - 7.7e-25 87.3 63.3 3.8e-17 62.0 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SAICAR_synt PF01259.13 EMC98163.1 - 1.4e-83 279.7 0.0 1.7e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 EMC98164.1 - 1.8e-30 104.5 2.9 3.7e-30 103.6 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 Exo_endo_phos PF03372.18 EMC98165.1 - 1.1e-11 45.1 0.0 1.9e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMC98165.1 - 4.1e-11 42.5 0.0 8e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EMC98165.1 - 0.00033 20.5 1.6 0.00081 19.2 1.1 1.7 1 0 0 1 1 1 1 GRF zinc finger Nyv1_N PF09426.5 EMC98165.1 - 0.044 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal HMG_box PF00505.14 EMC98166.1 - 2.9e-24 85.1 0.6 3.8e-24 84.7 0.4 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC98166.1 - 2.5e-05 24.5 0.4 3e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 HMG-box domain DUF1795 PF08786.6 EMC98166.1 - 0.096 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) UPF0150 PF03681.10 EMC98168.1 - 0.12 12.0 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) DUF3079 PF11278.3 EMC98169.1 - 0.057 12.9 1.4 0.071 12.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3079) DUF2404 PF10296.4 EMC98171.1 - 5.4e-25 87.3 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EMC98171.1 - 0.13 12.5 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 PH domain Abhydrolase_6 PF12697.2 EMC98172.1 - 4.1e-24 85.7 0.3 5.1e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC98172.1 - 7e-13 48.5 0.4 2.2e-12 46.9 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC98172.1 - 9.2e-08 31.9 0.7 4.4e-06 26.4 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMC98172.1 - 0.0033 16.9 0.4 0.015 14.7 0.0 2.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMC98172.1 - 0.0034 16.6 0.7 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 EMC98172.1 - 0.084 12.5 0.3 2.2 7.9 0.2 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 EMC98172.1 - 0.18 10.2 0.1 0.38 9.1 0.1 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF3433 PF11915.3 EMC98173.1 - 6.5e-26 90.3 8.5 1.3e-17 63.7 0.4 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DEAD PF00270.24 EMC98174.1 - 1.9e-43 147.8 0.0 5.4e-43 146.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC98174.1 - 1.6e-20 72.7 0.3 4.8e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMC98174.1 - 0.0061 15.4 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMC98174.1 - 0.0074 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EMC98174.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.1 EMC98174.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit HSP70 PF00012.15 EMC98175.1 - 1.1e-72 244.9 0.9 1.5e-72 244.4 0.6 1.2 1 0 0 1 1 1 1 Hsp70 protein PilM_2 PF11104.3 EMC98175.1 - 6.8e-05 21.9 0.1 0.00017 20.5 0.0 1.6 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; Nucleoplasmin PF03066.10 EMC98175.1 - 0.0028 17.1 3.8 0.0058 16.1 2.7 1.5 1 0 0 1 1 1 1 Nucleoplasmin DUF4611 PF15387.1 EMC98175.1 - 0.82 9.8 7.5 1.4 9.1 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 EMC98175.1 - 0.87 9.8 9.6 2.1 8.6 6.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EMC98175.1 - 0.95 9.0 7.5 0.66 9.5 3.6 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2457 PF10446.4 EMC98175.1 - 5.3 5.6 11.6 10 4.7 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Endonuc-BglII PF09195.6 EMC98176.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglII Ion_trans_2 PF07885.11 EMC98179.1 - 1.2e-30 105.0 24.1 7.6e-18 64.0 3.7 3.4 3 0 0 3 3 3 2 Ion channel VIT1 PF01988.14 EMC98179.1 - 0.0037 16.7 6.2 0.47 9.9 0.0 2.9 2 0 0 2 2 2 2 VIT family Polyketide_cyc PF03364.15 EMC98180.1 - 2.4e-07 30.8 0.0 1.1e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EMC98180.1 - 0.015 15.4 0.9 0.075 13.2 0.6 2.1 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Asp_protease_2 PF13650.1 EMC98180.1 - 0.072 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease PIG-L PF02585.12 EMC98182.1 - 3.2e-25 89.0 0.0 5e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Chs3p PF12271.3 EMC98183.1 - 1.9e-132 440.7 18.0 2.2e-132 440.5 12.5 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit PGP_phosphatase PF09419.5 EMC98185.1 - 4.5e-65 218.0 0.0 5.2e-65 217.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EMC98185.1 - 8.1e-07 28.6 0.0 5.7e-06 25.9 0.0 2.1 1 1 1 2 2 2 1 HAD-hyrolase-like Rhomboid PF01694.17 EMC98186.1 - 3.2e-35 121.2 11.1 3.2e-35 121.2 7.7 2.0 2 0 0 2 2 2 1 Rhomboid family vWA-TerF-like PF10138.4 EMC98187.1 - 6.7e-09 35.8 0.1 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EMC98187.1 - 0.0026 17.5 0.1 0.0041 16.8 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC98187.1 - 0.0063 16.6 0.2 0.018 15.1 0.2 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Pro_racemase PF05544.6 EMC98187.1 - 0.018 13.8 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Proline racemase PseudoU_synth_2 PF00849.17 EMC98188.1 - 1.6e-30 106.1 0.0 2.4e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EMC98188.1 - 0.024 14.0 1.8 0.027 13.8 0.2 1.9 2 0 0 2 2 2 0 S4 domain Auto_anti-p27 PF06677.7 EMC98188.1 - 0.044 13.5 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Sugar_tr PF00083.19 EMC98190.1 - 9.4e-67 225.5 21.4 1.1e-66 225.3 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC98190.1 - 3.7e-25 88.3 29.2 4.6e-25 88.0 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyridoxal_deC PF00282.14 EMC98191.1 - 7.7e-116 386.5 0.0 1e-115 386.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1382 PF07131.6 EMC98191.1 - 0.0055 16.7 0.0 0.22 11.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1382) Aminotran_1_2 PF00155.16 EMC98191.1 - 0.06 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 EMC98191.1 - 0.061 11.7 0.0 0.098 11.1 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) LINES_C PF14695.1 EMC98191.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Lines C-terminus Tyr-DNA_phospho PF06087.7 EMC98192.1 - 6.6e-67 226.0 0.0 7.7e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EMC98192.1 - 0.00029 20.5 0.0 0.019 14.7 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain WD40 PF00400.27 EMC98193.1 - 2.5e-23 81.0 3.0 3.2e-06 26.7 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Met_asp_mut_E PF06368.6 EMC98193.1 - 0.012 13.8 0.1 0.07 11.3 0.0 1.9 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) Gmad1 PF10647.4 EMC98193.1 - 0.019 14.4 0.1 0.16 11.3 0.0 2.3 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain S1 PF00575.18 EMC98194.1 - 2.8e-79 261.1 19.4 5.9e-16 58.3 0.1 11.8 12 0 0 12 12 12 10 S1 RNA binding domain TPR_14 PF13428.1 EMC98194.1 - 1.9e-06 27.9 2.0 0.33 11.7 0.0 5.4 2 2 2 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 EMC98194.1 - 9.4e-06 25.5 14.3 0.011 15.4 0.0 4.2 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EMC98194.1 - 0.0035 16.9 0.0 0.0092 15.6 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.1 EMC98194.1 - 0.0094 16.2 0.1 1.4 9.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat FLgD_tudor PF13861.1 EMC98194.1 - 0.031 14.2 1.3 0.31 11.0 0.1 3.3 3 0 0 3 3 3 0 FlgD Tudor-like domain TPR_12 PF13424.1 EMC98194.1 - 0.037 13.9 1.3 6.7 6.7 0.0 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat EXOSC1 PF10447.4 EMC98194.1 - 0.092 12.7 12.4 0.29 11.1 0.2 5.9 6 1 0 7 7 7 0 Exosome component EXOSC1/CSL4 Abhydrolase_6 PF12697.2 EMC98195.1 - 1.7e-15 57.5 0.5 2.3e-15 57.1 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC98195.1 - 3.8e-08 33.1 0.0 7.9e-08 32.1 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC98195.1 - 0.054 12.7 0.1 1.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ran_BP1 PF00638.13 EMC98197.1 - 8.1e-49 164.7 1.0 1.3e-48 164.0 0.7 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EMC98197.1 - 0.00018 21.1 0.2 0.0015 18.1 0.1 2.2 1 1 0 1 1 1 1 WH1 domain Phosphoprotein PF00922.12 EMC98197.1 - 2 7.5 7.2 3 6.9 5.0 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein YEATS PF03366.11 EMC98198.1 - 9.5e-20 70.1 0.0 2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 YEATS family SLX9 PF15341.1 EMC98198.1 - 0.019 15.4 0.7 0.037 14.4 0.5 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 MgtE_N PF03448.12 EMC98198.1 - 0.086 13.1 0.8 0.15 12.3 0.5 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain zf-RING_2 PF13639.1 EMC98199.1 - 1.5e-10 40.6 4.8 7.4e-10 38.4 3.3 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC98199.1 - 1.1e-09 38.2 0.1 1.9e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC98199.1 - 2.9e-08 33.2 0.4 5.6e-08 32.3 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC98199.1 - 7.9e-08 31.8 0.4 1.4e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC98199.1 - 1.2e-06 28.0 1.2 3.3e-06 26.6 0.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC98199.1 - 9.4e-05 22.3 2.1 9.4e-05 22.3 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC98199.1 - 0.014 15.2 0.9 0.014 15.2 0.7 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 EMC98199.1 - 0.014 13.1 3.6 0.078 10.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2921) zf-RING_UBOX PF13445.1 EMC98199.1 - 0.041 13.6 0.6 0.041 13.6 0.4 2.2 2 1 1 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.3 EMC98199.1 - 0.13 12.2 2.0 0.42 10.6 1.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EMC98199.1 - 1.6 8.8 3.9 0.79 9.8 0.8 1.8 2 0 0 2 2 2 0 RING-variant domain Complex1_LYR_1 PF13232.1 EMC98201.1 - 1.5e-18 66.7 7.2 2e-18 66.3 5.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMC98201.1 - 1.9e-17 62.8 6.3 2.6e-17 62.3 4.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EMC98201.1 - 0.0068 16.8 4.0 0.0081 16.6 2.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DASH_Spc34 PF08657.5 EMC98201.1 - 0.045 13.4 0.4 0.055 13.1 0.3 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 SUR7 PF06687.7 EMC98202.1 - 1.7e-26 93.0 16.0 2.2e-26 92.7 11.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 EMC98202.1 - 1.7 8.7 7.3 0.073 13.1 1.0 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding FMO-like PF00743.14 EMC98203.1 - 3.2e-23 81.7 0.0 7.3e-23 80.5 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMC98203.1 - 2.6e-19 70.0 0.0 6.2e-19 68.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC98203.1 - 7.4e-11 42.2 0.0 3.3e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC98203.1 - 4.1e-10 39.0 0.1 1.2e-08 34.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMC98203.1 - 2.3e-07 30.7 0.6 1.1e-06 28.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC98203.1 - 1.1e-05 25.7 0.8 0.12 12.8 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC98203.1 - 2e-05 23.6 1.0 2.4e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EMC98203.1 - 0.001 19.1 0.3 0.064 13.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EMC98203.1 - 0.015 15.0 1.6 1 9.1 0.1 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EMC98203.1 - 0.04 13.5 0.2 0.074 12.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EMC98203.1 - 0.062 13.5 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EMC98203.1 - 0.34 9.6 1.6 0.55 9.0 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain WBP-1 PF11669.3 EMC98204.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 PepSY_TM_1 PF13172.1 EMC98204.1 - 2.7 7.8 8.4 7.2 6.4 5.8 1.7 1 0 0 1 1 1 0 PepSY-associated TM helix Tub_2 PF04525.7 EMC98205.1 - 1.2e-13 50.8 0.0 1.5e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 Med2 PF11214.3 EMC98206.1 - 0.13 12.3 0.2 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 2 ApbA_C PF08546.6 EMC98206.1 - 0.13 12.2 1.5 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal RRM_1 PF00076.17 EMC98207.1 - 8.6e-61 201.5 0.0 4e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC98207.1 - 5e-45 151.3 0.0 2.9e-14 52.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC98207.1 - 8.8e-33 111.9 0.1 9.3e-12 44.6 0.0 3.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC98207.1 - 1e-05 25.2 0.0 1 9.2 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EMC98207.1 - 0.0026 17.6 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 EMC98207.1 - 0.11 12.4 0.0 5.6 6.8 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif POT1 PF02765.12 EMC98208.1 - 4.4e-16 59.1 0.1 1.2e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 DDRGK PF09756.4 EMC98208.1 - 0.33 10.3 8.9 0.48 9.8 6.2 1.2 1 0 0 1 1 1 0 DDRGK domain Arm PF00514.18 EMC98209.1 - 7.5e-96 311.0 12.3 3.6e-14 51.9 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC98209.1 - 2.3e-30 104.6 7.0 4.5e-11 42.8 0.0 5.7 1 1 5 6 6 6 6 HEAT repeats IBB PF01749.15 EMC98209.1 - 5.5e-23 80.9 0.9 1e-22 80.1 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EMC98209.1 - 3.8e-22 78.1 10.2 4.3e-10 39.7 0.1 6.3 5 1 2 7 7 7 3 HEAT-like repeat HEAT PF02985.17 EMC98209.1 - 1.6e-21 74.4 0.7 1.2e-06 28.0 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.8 EMC98209.1 - 1.5e-10 40.6 0.0 0.015 14.4 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EMC98209.1 - 1.1e-06 27.3 0.0 0.00014 20.3 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EMC98209.1 - 7.5e-05 22.6 0.0 0.84 9.5 0.0 4.6 3 1 1 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EMC98209.1 - 0.0042 15.4 0.0 0.1 10.8 0.0 2.5 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.1 EMC98209.1 - 0.0057 16.5 4.5 2.2 8.2 0.0 4.8 3 2 3 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EMC98209.1 - 0.025 14.9 7.9 0.46 11.0 0.1 5.0 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat Glycos_trans_3N PF02885.12 EMC98209.1 - 0.05 13.1 0.0 99 2.6 0.0 4.0 4 0 0 4 4 4 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.6 EMC98209.1 - 0.24 10.3 0.0 0.65 8.9 0.0 1.6 1 1 0 1 1 1 0 Mo25-like SURF6 PF04935.7 EMC98209.1 - 2.1 7.5 8.5 3.2 6.9 5.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 YjeF_N PF03853.10 EMC98210.1 - 2.9e-23 82.3 0.1 4.3e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EMC98210.1 - 2.4e-08 34.4 1.0 2.4e-08 34.4 0.7 2.2 1 1 1 2 2 2 1 FDF domain Tnp_P_element PF12017.3 EMC98211.1 - 0.0067 15.6 0.1 0.59 9.3 0.0 2.4 2 1 0 2 2 2 2 Transposase protein Seryl_tRNA_N PF02403.17 EMC98211.1 - 0.04 13.9 0.7 4 7.5 0.0 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.6 EMC98211.1 - 0.04 13.8 2.1 0.087 12.8 0.2 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.3 EMC98211.1 - 0.19 11.5 2.0 0.61 9.9 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Glyco_hydro_9 PF00759.14 EMC98212.1 - 7e-108 361.3 8.4 8.8e-108 361.0 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CelD_N PF02927.9 EMC98212.1 - 3.3e-23 81.7 0.1 9e-23 80.3 0.1 1.7 1 0 0 1 1 1 1 N-terminal ig-like domain of cellulase Myb_DNA-bind_6 PF13921.1 EMC98213.1 - 1.8e-14 53.5 0.1 9.3e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMC98213.1 - 6.6e-13 48.5 0.5 2.1e-07 30.8 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Phosducin PF02114.11 EMC98214.1 - 5e-12 45.1 0.0 6.6e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Phosducin HECT PF00632.20 EMC98215.1 - 1.1e-80 271.1 0.0 1.6e-80 270.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EMC98215.1 - 0.001 18.5 1.6 0.0046 16.4 1.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif MFS_1 PF07690.11 EMC98216.1 - 3.7e-21 75.2 37.6 3.7e-21 75.2 26.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Prenyltransf PF01255.14 EMC98217.1 - 2.5e-72 242.6 5.2 3.8e-53 179.9 0.1 2.0 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Arena_RNA_pol PF06317.6 EMC98217.1 - 0.11 9.1 0.0 0.13 8.8 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Alpha-amylase PF00128.19 EMC98218.1 - 1.6e-18 67.1 3.4 9.2e-18 64.6 2.3 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EMC98218.1 - 2.1e-15 56.8 0.0 4.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EMC98218.1 - 3.8e-07 29.6 0.0 6.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMC98218.1 - 4e-07 30.2 0.0 1.1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Suc_Fer-like PF06999.7 EMC98219.1 - 1.2e-32 113.8 0.0 2e-32 113.0 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer4_2 PF12797.2 EMC98219.1 - 0.14 12.1 1.2 1.2 9.2 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain P22_Cro PF14549.1 EMC98220.1 - 0.12 12.1 0.4 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro Acetyltransf_1 PF00583.19 EMC98221.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC98221.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC98221.1 - 0.0069 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EMC98221.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein ADH_zinc_N PF00107.21 EMC98222.1 - 2.5e-14 52.9 0.0 2e-13 49.9 0.0 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC98222.1 - 1.2e-07 31.4 0.1 1.1e-05 25.1 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMC98222.1 - 0.0061 17.4 0.0 0.017 16.0 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PH_10 PF15411.1 EMC98223.1 - 2.6e-42 143.6 0.0 8.4e-42 142.0 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 EMC98223.1 - 3.7e-31 108.3 0.9 5.9e-31 107.7 0.7 1.3 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 EMC98223.1 - 7.2e-31 106.0 0.0 1.6e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 EMC98223.1 - 1.7e-05 24.3 0.0 0.00011 21.7 0.0 2.4 1 1 0 1 1 1 1 PB1 domain PH PF00169.24 EMC98223.1 - 0.00022 21.3 0.0 0.00045 20.3 0.0 1.5 1 0 0 1 1 1 1 PH domain WD40 PF00400.27 EMC98225.1 - 2.8e-36 122.0 18.4 1.2e-06 28.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EMC98225.1 - 2.4e-11 43.1 0.7 7.5e-11 41.5 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC98225.1 - 3.2e-07 29.8 0.2 8.8e-07 28.4 0.2 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EMC98225.1 - 9.6e-05 20.7 4.5 0.22 9.6 0.1 3.2 2 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMC98225.1 - 0.015 14.7 0.1 0.29 10.5 0.0 2.7 3 1 0 3 3 3 0 PQQ-like domain Nucleoporin_N PF08801.6 EMC98225.1 - 0.073 11.7 2.3 6.2 5.4 0.1 3.2 2 1 1 3 3 3 0 Nup133 N terminal like HALZ PF02183.13 EMC98226.1 - 0.068 12.8 0.5 0.13 11.9 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper LemA PF04011.7 EMC98226.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 LemA family WD40 PF00400.27 EMC98227.1 - 3.2e-76 248.7 19.8 4e-13 48.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC98227.1 - 5.4e-06 25.4 0.1 1.9 7.1 0.0 4.1 1 1 2 4 4 4 4 Nup133 N terminal like Nup160 PF11715.3 EMC98227.1 - 6.5e-06 24.5 4.8 0.00049 18.3 0.4 3.8 4 1 0 4 4 4 2 Nucleoporin Nup120/160 VID27 PF08553.5 EMC98227.1 - 0.01 14.1 0.0 0.017 13.3 0.0 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein MHC2-interact PF09307.5 EMC98227.1 - 0.047 13.4 0.2 0.084 12.6 0.2 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting IncA PF04156.9 EMC98228.1 - 4.7e-05 23.0 7.7 0.00012 21.7 5.3 1.6 1 0 0 1 1 1 1 IncA protein CLASP_N PF12348.3 EMC98228.1 - 0.00061 19.2 0.0 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 EMC98228.1 - 0.0015 18.4 0.6 26 5.2 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat Myosin_tail_1 PF01576.14 EMC98228.1 - 0.0022 15.8 9.6 0.0022 15.8 6.7 1.5 2 0 0 2 2 2 1 Myosin tail bZIP_1 PF00170.16 EMC98228.1 - 0.029 14.3 10.2 0.69 9.9 0.5 3.0 2 0 0 2 2 2 0 bZIP transcription factor Macoilin PF09726.4 EMC98228.1 - 0.14 10.4 3.9 0.21 9.8 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 EMC98228.1 - 0.31 10.0 11.3 0.65 8.9 7.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EMC98228.1 - 2.7 6.8 9.5 5.1 5.9 6.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 EMC98228.1 - 2.9 7.6 11.7 2.6 7.7 0.7 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 EMC98228.1 - 5.7 6.4 13.4 13 5.3 4.8 2.9 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 EMC98228.1 - 9.1 6.1 17.3 1.8 8.4 2.0 3.7 2 1 1 3 3 3 0 Basic region leucine zipper DUF1100 PF06500.6 EMC98230.1 - 3.3e-12 45.7 0.0 4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EMC98230.1 - 1.1e-10 41.3 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC98230.1 - 6.2e-09 36.0 0.1 1.1e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMC98230.1 - 5.5e-06 25.9 0.0 7.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EMC98230.1 - 3.2e-05 23.2 0.0 6.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EMC98230.1 - 0.0061 16.0 0.0 0.031 13.7 0.0 2.1 1 1 0 1 1 1 1 Putative esterase MIT PF04212.13 EMC98230.1 - 0.46 10.4 3.9 0.87 9.5 2.7 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Usp PF00582.21 EMC98231.1 - 7.5e-17 61.8 1.4 1.3e-12 48.1 0.1 2.9 3 0 0 3 3 3 2 Universal stress protein family p450 PF00067.17 EMC98232.1 - 4.2e-37 127.7 0.0 5.7e-36 124.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EMC98233.1 - 5.1e-06 26.1 0.1 2.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMC98233.1 - 8.9e-05 22.0 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain Lactonase PF10282.4 EMC98233.1 - 0.086 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EMC98233.1 - 0.11 12.4 0.8 5.2 7.1 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Zn_clus PF00172.13 EMC98235.1 - 5.8e-08 32.5 7.3 9.3e-08 31.8 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.1 EMC98236.1 - 6.7e-14 51.7 1.7 1.4e-13 50.6 1.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family 7tm_1 PF00001.16 EMC98236.1 - 0.017 14.2 4.3 0.028 13.5 3.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Zn_clus PF00172.13 EMC98237.1 - 0.0041 16.9 7.9 0.01 15.7 5.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyltransferase PF01553.16 EMC98239.1 - 7.8e-13 48.0 0.0 2.5e-05 23.7 0.0 2.7 3 0 0 3 3 3 2 Acyltransferase Glyco_hydro_47 PF01532.15 EMC98240.1 - 4.5e-120 401.3 1.1 5.9e-120 400.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ATP-synt_C PF00137.16 EMC98242.1 - 1.4e-15 56.8 12.6 2.5e-15 56.1 8.7 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Enamelin PF15362.1 EMC98242.1 - 0.098 10.7 0.1 0.12 10.4 0.1 1.0 1 0 0 1 1 1 0 Enamelin DUF1469 PF07332.6 EMC98242.1 - 1.4 8.7 6.7 2.9 7.6 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) 2OG-FeII_Oxy PF03171.15 EMC98243.1 - 4.5e-19 68.5 0.0 7.1e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMC98243.1 - 1.5e-10 41.6 0.0 2.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal SAPS PF04499.10 EMC98244.1 - 1.4e-183 610.9 0.0 6e-183 608.8 0.0 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein WWbp PF10349.4 EMC98245.1 - 1.2e-16 61.6 0.5 1.2e-16 61.6 0.3 2.0 2 0 0 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 EMC98245.1 - 0.0022 17.4 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 EMC98245.1 - 0.0047 16.7 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 ADH_zinc_N PF00107.21 EMC98246.1 - 5e-18 64.8 0.5 8.3e-18 64.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC98246.1 - 5.6e-17 62.8 0.3 2e-16 61.0 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC98246.1 - 5.1e-11 42.3 0.0 6e-09 35.6 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMC98246.1 - 0.0087 15.6 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMC98246.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans_2 PF11951.3 EMC98247.1 - 1e-10 40.8 3.9 5.9e-10 38.2 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC98247.1 - 5.2e-07 29.4 10.8 9.8e-07 28.5 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.18 EMC98250.1 - 5e-77 258.4 1.3 9.8e-77 257.4 0.9 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC98250.1 - 1.1e-44 150.8 0.1 2.1e-44 149.8 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EMC98250.1 - 0.0093 15.9 0.0 0.031 14.3 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 EMC98250.1 - 0.018 14.5 2.3 0.24 10.8 0.6 3.0 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain DUF3520 PF12034.3 EMC98250.1 - 0.049 13.7 0.2 0.38 10.8 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3520) CutC PF03932.9 EMC98251.1 - 4.9e-61 205.5 0.0 5.8e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 CutC family TMP-TENI PF02581.12 EMC98251.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI TP_methylase PF00590.15 EMC98252.1 - 1.9e-47 161.7 1.3 2.2e-47 161.4 0.1 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EMC98252.1 - 1.3e-11 44.6 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EMC98252.1 - 2.7e-09 36.1 0.0 6.1e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EMC98252.1 - 0.00089 18.1 0.0 0.0022 16.9 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rogdi_lz PF10259.4 EMC98253.1 - 1.5e-79 266.9 0.0 1.8e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.7 EMC98254.1 - 1.8e-26 93.0 8.5 2.2e-26 92.7 5.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EMC98254.1 - 0.076 12.6 21.8 0.16 11.6 15.1 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 EMC98254.1 - 0.16 11.5 10.4 0.31 10.6 7.2 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein Fig1 PF12351.3 EMC98254.1 - 1.4 8.7 16.7 3.4 7.4 11.5 1.7 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3435 PF11917.3 EMC98256.1 - 1.3e-10 40.6 0.0 1.3e-08 34.0 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3435) zf-Di19 PF05605.7 EMC98256.1 - 0.0026 17.8 0.2 0.0068 16.5 0.2 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EMC98256.1 - 0.51 10.7 3.6 7.1 7.2 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger MFS_1 PF07690.11 EMC98259.1 - 2.4e-43 148.2 29.8 2.4e-43 148.2 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98259.1 - 8.5e-18 64.1 20.7 6e-17 61.3 14.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMC98259.1 - 4.2e-05 21.9 2.4 6.6e-05 21.2 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EMC98259.1 - 0.00074 17.7 0.8 0.0011 17.1 0.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EMC98259.1 - 0.34 8.9 3.9 0.39 8.7 1.3 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Vps51 PF08700.6 EMC98260.1 - 0.021 14.6 1.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 Vps51/Vps67 Peptidase_S9 PF00326.16 EMC98260.1 - 0.13 11.4 2.6 0.2 10.8 1.8 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1510 PF07423.6 EMC98261.1 - 1.5 8.1 10.3 4.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EMC98261.1 - 5.9 4.6 15.9 0.089 10.6 6.1 1.4 2 0 0 2 2 2 0 Nop14-like family Gly-zipper_OmpA PF13436.1 EMC98262.1 - 0.00042 19.9 3.9 0.00042 19.9 2.7 2.4 3 0 0 3 3 3 1 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 EMC98262.1 - 0.00068 19.2 17.9 0.00068 19.2 12.4 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF533 PF04391.7 EMC98262.1 - 0.015 14.6 3.2 0.015 14.6 2.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF533) TraT PF05818.7 EMC98262.1 - 0.17 11.3 0.2 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_YMGG PF13441.1 EMC98262.1 - 0.44 10.0 15.0 1.3 8.5 10.4 1.8 1 0 0 1 1 1 0 YMGG-like Gly-zipper RCC1_2 PF13540.1 EMC98263.1 - 1.2e-06 27.9 18.4 0.032 13.8 0.0 5.6 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EMC98263.1 - 7.8e-06 25.5 1.5 1.1e-05 25.0 0.3 1.9 2 0 0 2 2 2 1 F-box-like RCC1 PF00415.13 EMC98263.1 - 0.0006 19.9 10.1 0.014 15.6 0.2 4.8 6 1 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.28 EMC98263.1 - 0.001 18.6 0.2 0.0022 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EMC98263.1 - 0.063 13.0 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain Acetyltransf_1 PF00583.19 EMC98264.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMC98264.1 - 1.3e-06 28.4 0.0 2.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC98264.1 - 1.4e-06 28.3 0.1 6.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC98264.1 - 0.00046 20.0 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC98264.1 - 0.00068 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EMC98264.1 - 0.0073 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase EF-hand_7 PF13499.1 EMC98266.1 - 0.0036 17.4 0.0 0.25 11.5 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC98266.1 - 0.058 13.0 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Med3 PF11593.3 EMC98266.1 - 4.2 6.5 6.0 5.1 6.2 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DOT1 PF08123.8 EMC98267.1 - 4.7e-69 231.7 0.0 6.6e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 EMC98267.1 - 5.3e-05 22.8 0.0 8.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC98267.1 - 0.00031 20.7 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC98267.1 - 0.0006 20.3 0.1 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Nucleo_P87 PF07267.6 EMC98267.1 - 0.064 11.9 2.4 0.094 11.3 1.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1264 PF06884.6 EMC98268.1 - 5.3e-73 244.0 0.1 6.3e-73 243.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF4449 PF14613.1 EMC98269.1 - 7.6e-66 221.0 6.7 7.6e-66 221.0 4.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Med23 PF11573.3 EMC98269.1 - 0.014 12.7 5.4 0.008 13.5 1.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 23 DNMT1-RFD PF12047.3 EMC98270.1 - 0.038 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain AT_hook PF02178.14 EMC98270.1 - 0.92 9.3 7.3 3.3 7.7 5.1 2.0 1 0 0 1 1 1 0 AT hook motif TruB_N PF01509.13 EMC98271.1 - 1.5e-47 161.5 0.0 1.1e-46 158.6 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Cyclase PF04199.8 EMC98272.1 - 7e-36 123.4 0.0 9.3e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF3176 PF11374.3 EMC98273.1 - 0.00033 20.5 0.1 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF1842 PF08896.5 EMC98273.1 - 0.051 13.3 0.1 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1842) HSP20 PF00011.16 EMC98274.1 - 1.3e-10 41.0 0.0 1.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF4211 PF13926.1 EMC98275.1 - 6.3e-33 113.3 1.1 1.2e-32 112.3 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4211) Zn_clus PF00172.13 EMC98275.1 - 0.023 14.6 0.7 0.045 13.6 0.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-B_dimeris PF09026.5 EMC98275.1 - 0.15 12.2 6.9 0.33 11.2 1.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DcpS_C PF11969.3 EMC98276.1 - 1.5e-15 57.4 3.2 7.8e-15 55.1 1.2 2.4 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EMC98276.1 - 1e-14 54.8 0.0 2.4e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 HIT domain Amidase PF01425.16 EMC98278.1 - 2.6e-55 188.0 0.5 6.9e-53 180.0 0.1 2.1 2 0 0 2 2 2 2 Amidase Arm PF00514.18 EMC98279.1 - 6.8e-72 235.0 27.2 9.7e-13 47.4 0.0 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC98279.1 - 4.6e-25 87.7 13.9 3.5e-05 23.9 0.0 7.6 3 2 5 8 8 8 7 HEAT repeats HEAT PF02985.17 EMC98279.1 - 1.2e-21 74.8 11.1 0.02 14.9 0.0 9.7 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 EMC98279.1 - 2.6e-13 50.0 16.5 0.23 11.9 0.2 8.5 9 1 1 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 EMC98279.1 - 1.2e-12 46.9 2.2 5.2e-07 28.3 0.1 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 EMC98279.1 - 1.4e-12 47.2 2.5 0.0039 16.3 0.0 3.4 2 1 1 3 3 3 3 Armadillo-like KAP PF05804.7 EMC98279.1 - 2e-09 35.9 0.1 5.9e-09 34.4 0.0 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EMC98279.1 - 4.6e-07 29.2 0.0 0.0037 16.4 0.0 3.3 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 EMC98279.1 - 0.018 14.9 2.9 3.3 7.6 0.0 4.3 3 1 1 4 4 4 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EMC98279.1 - 0.068 13.5 0.0 1.4 9.3 0.0 3.2 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region DUF350 PF03994.9 EMC98279.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) HEAT_PBS PF03130.11 EMC98279.1 - 0.13 12.8 7.9 45 4.9 0.1 6.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Pkinase PF00069.20 EMC98280.1 - 3.4e-47 160.7 0.0 4.4e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC98280.1 - 9.8e-30 103.4 0.0 7.9e-29 100.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC98280.1 - 0.11 11.4 0.0 0.37 9.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like EamA PF00892.15 EMC98282.1 - 1.1e-09 38.3 32.5 3.3e-09 36.8 2.6 3.0 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 EMC98282.1 - 8e-09 35.3 19.1 4.1e-05 23.2 0.1 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 EMC98282.1 - 3.9e-07 30.2 7.2 3.9e-07 30.2 5.0 3.3 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EMC98282.1 - 3.2e-06 26.2 8.4 8.9e-06 24.7 3.9 2.6 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EMC98282.1 - 0.00024 20.1 9.3 0.00043 19.3 5.7 1.7 2 0 0 2 2 2 1 UAA transporter family Methyltransf_23 PF13489.1 EMC98284.1 - 2.3e-16 59.9 0.0 3.2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC98284.1 - 2.8e-11 43.7 0.0 4.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC98284.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC98284.1 - 4.7e-09 36.8 0.0 7.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC98284.1 - 5.3e-08 33.2 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC98284.1 - 2.9e-06 26.5 0.0 4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMC98284.1 - 6.6e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC98284.1 - 0.00077 19.7 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EMC98284.1 - 0.012 16.4 0.0 0.038 14.8 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 EMC98284.1 - 0.058 12.9 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 EMC98284.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) IcmF-related PF06761.7 EMC98284.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Methyltransf_4 PF02390.12 EMC98284.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_21 PF05050.7 EMC98284.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase FkbM domain Porin_3 PF01459.17 EMC98288.1 - 3.5e-73 246.2 0.0 4.2e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.13 EMC98289.1 - 2.1e-64 216.6 0.1 3e-64 216.1 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMC98289.1 - 6.1e-23 81.6 0.7 9.8e-23 80.9 0.5 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMC98289.1 - 2.4e-05 24.2 0.0 6.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC98289.1 - 0.00037 21.3 0.0 0.0014 19.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMC98289.1 - 0.0005 19.3 0.0 0.00087 18.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 EMC98289.1 - 0.0048 16.5 0.0 0.079 12.6 0.0 2.2 1 1 0 1 1 1 1 Adenylylsulphate kinase DUF4112 PF13430.1 EMC98290.1 - 3.2e-31 107.3 0.7 4.2e-31 107.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Lung_7-TM_R PF06814.8 EMC98291.1 - 5.3e-69 232.4 16.5 6.5e-69 232.1 11.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 EMC98291.1 - 0.21 11.7 21.1 1.6 8.9 0.7 3.8 1 1 3 4 4 4 0 PrgI family protein GATA PF00320.22 EMC98293.1 - 6e-05 22.3 2.6 0.042 13.2 0.4 2.7 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.17 EMC98294.1 - 1.6e-18 66.0 0.1 2.1e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 EMC98294.1 - 0.066 11.8 0.0 0.08 11.5 0.0 1.0 1 0 0 1 1 1 0 Baculovirus hypothetical protein Dak1 PF02733.12 EMC98295.1 - 3e-117 390.8 7.2 4.5e-117 390.2 5.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EMC98295.1 - 4.7e-45 153.3 4.6 4.7e-45 153.3 3.2 2.0 2 0 0 2 2 2 1 DAK2 domain DUF1442 PF07279.6 EMC98295.1 - 0.23 10.5 2.8 0.61 9.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) PEX11 PF05648.9 EMC98297.1 - 1.6e-08 34.1 0.5 5.4e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) TFIIE_beta PF02186.10 EMC98298.1 - 3.1e-06 27.0 0.1 9.7e-06 25.4 0.1 1.9 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF1250 PF06855.7 EMC98298.1 - 0.11 12.0 0.0 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Pyr_redox_3 PF13738.1 EMC98299.1 - 2.3e-16 60.4 0.2 4.3e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC98299.1 - 1.4e-13 49.9 0.0 1.5e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMC98299.1 - 9.8e-11 41.9 0.0 4.2e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC98299.1 - 1.6e-10 40.4 0.1 2.8e-07 29.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMC98299.1 - 6.7e-08 31.8 0.1 4e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC98299.1 - 6.6e-07 29.6 0.6 0.033 14.6 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC98299.1 - 1.7e-06 27.9 0.0 6.3e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMC98299.1 - 1.8e-05 23.9 1.5 2.4e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EMC98299.1 - 0.00018 21.2 0.0 0.39 10.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EMC98299.1 - 0.00034 19.5 0.1 0.00068 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMC98299.1 - 0.00041 19.5 0.0 0.001 18.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EMC98299.1 - 0.00041 19.5 0.0 0.026 13.6 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EMC98299.1 - 0.0017 17.3 0.2 0.011 14.6 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 EMC98299.1 - 0.0023 16.4 0.0 0.093 11.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 EMC98299.1 - 0.0038 16.4 0.0 0.94 8.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMC98299.1 - 0.0083 15.7 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMC98299.1 - 0.14 12.1 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Cu-oxidase_3 PF07732.10 EMC98300.1 - 4.7e-40 135.9 9.1 8.8e-39 131.8 0.8 4.1 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC98300.1 - 2.4e-38 130.7 6.1 5.1e-37 126.4 0.2 3.9 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EMC98300.1 - 1.2e-31 109.7 0.8 1.2e-31 109.7 0.5 2.0 3 0 0 3 3 3 1 Multicopper oxidase OCD_Mu_crystall PF02423.10 EMC98302.1 - 3.3e-15 55.6 0.7 4.4e-07 28.9 0.2 3.7 3 1 1 4 4 4 3 Ornithine cyclodeaminase/mu-crystallin family DUF607 PF04678.8 EMC98303.1 - 6.9e-43 146.6 2.0 9.8e-42 142.9 1.4 2.6 1 1 0 1 1 1 1 Protein of unknown function, DUF607 Mito_carr PF00153.22 EMC98304.1 - 1.7e-65 216.7 2.6 3e-23 81.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Esterase_phd PF10503.4 EMC98305.1 - 1.5e-06 27.6 0.0 1.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMC98305.1 - 1.2e-05 24.6 0.6 5.6e-05 22.4 0.2 2.1 1 1 2 3 3 3 1 Prolyl oligopeptidase family Esterase PF00756.15 EMC98305.1 - 9.7e-05 21.9 0.2 0.00012 21.6 0.1 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EMC98305.1 - 0.00012 21.8 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC98305.1 - 0.0023 17.4 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EMC98305.1 - 0.015 13.8 0.2 0.5 8.8 0.2 2.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EMC98305.1 - 0.045 13.3 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L7Ae PF01248.21 EMC98306.1 - 1.2e-20 72.7 0.7 1.9e-20 72.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RepB PF07506.6 EMC98306.1 - 0.023 14.5 1.1 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 RepB plasmid partitioning protein Sld5 PF05916.6 EMC98308.1 - 4.9e-14 52.5 0.0 6.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein ATC_hydrolase PF14196.1 EMC98308.1 - 0.075 13.4 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF3437 PF11919.3 EMC98309.1 - 1e-32 111.6 0.0 3.9e-32 109.8 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EMC98309.1 - 7.8e-05 22.4 0.7 0.87 9.8 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.3 EMC98309.1 - 0.003 16.9 0.1 0.24 10.7 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal KaiC PF06745.8 EMC98309.1 - 0.14 11.2 0.2 0.29 10.1 0.1 1.4 1 0 0 1 1 1 0 KaiC Lipase_3 PF01764.20 EMC98310.1 - 1.1e-15 57.5 0.0 1.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EMC98310.1 - 0.014 14.7 0.0 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.2 EMC98310.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme peroxidase PF00141.18 EMC98311.1 - 2.6e-48 164.4 0.0 3.5e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase NTP_transferase PF00483.18 EMC98314.1 - 1.1e-48 165.7 0.0 2.3e-48 164.6 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EMC98314.1 - 6.2e-17 60.2 11.8 2.7e-10 39.2 1.1 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMC98314.1 - 5e-11 42.9 0.0 7.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EMC98314.1 - 1.1e-06 28.0 0.7 1.1e-06 28.0 0.5 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EMC98314.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DND1_DSRM PF14709.1 EMC98315.1 - 0.00019 21.6 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EMC98315.1 - 0.001 19.5 0.1 0.0025 18.3 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif BRAP2 PF07576.7 EMC98316.1 - 3.4e-22 78.0 0.0 6.4e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EMC98316.1 - 3.3e-20 71.9 8.8 8.6e-20 70.6 6.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EMC98316.1 - 2.3e-09 36.9 9.6 2.3e-09 36.9 6.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC98316.1 - 5.2e-05 22.8 7.3 5.2e-05 22.8 5.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC98316.1 - 0.00023 20.8 6.5 0.00023 20.8 4.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC98316.1 - 0.00034 20.6 4.5 0.0011 19.0 3.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC98316.1 - 0.00097 19.1 8.6 0.00097 19.1 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC98316.1 - 0.0012 18.4 6.9 0.0012 18.4 4.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC98316.1 - 0.0045 16.6 4.2 0.0062 16.2 1.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EMC98316.1 - 0.013 15.2 3.5 0.013 15.2 2.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EMC98316.1 - 0.023 14.5 5.6 0.068 13.0 3.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Amidohydro_1 PF01979.15 EMC98316.1 - 0.034 13.8 1.3 0.05 13.2 0.9 1.2 1 0 0 1 1 1 0 Amidohydrolase family DUF445 PF04286.7 EMC98316.1 - 0.056 12.9 8.2 0.077 12.5 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Baculo_RING PF05883.6 EMC98316.1 - 0.11 12.3 2.8 0.091 12.6 0.2 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Prok-RING_4 PF14447.1 EMC98316.1 - 0.8 9.2 9.6 22 4.6 6.7 2.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1993 PF09351.5 EMC98316.1 - 1.2 9.0 9.7 0.24 11.3 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) ubiquitin PF00240.18 EMC98317.1 - 9.8e-103 335.6 15.6 6.5e-34 115.1 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EMC98317.1 - 1.8e-59 197.3 13.8 2.5e-19 68.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC98317.1 - 6.1e-19 68.0 6.5 9e-05 22.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMC98317.1 - 7.6e-17 61.4 0.5 0.00041 20.0 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMC98317.1 - 6.7e-11 42.0 1.2 0.078 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMC98317.1 - 1.2e-10 41.4 0.7 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EMC98317.1 - 5.1e-08 32.8 0.0 0.99 9.4 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EMC98317.1 - 2e-05 24.3 2.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 EMC98317.1 - 0.00019 21.0 0.5 8.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 EMC98317.1 - 0.00044 19.9 2.4 9.2 6.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Methyltrans_RNA PF04452.9 EMC98317.1 - 0.00081 18.5 0.1 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Plexin_cytopl PF08337.7 EMC98317.1 - 0.00084 17.7 8.1 1.5 7.0 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EMC98317.1 - 0.011 15.2 0.0 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 EMC98317.1 - 0.015 15.3 2.7 31 4.7 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 EMC98317.1 - 0.02 15.2 0.4 68 3.9 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 EMC98317.1 - 0.032 14.1 3.9 26 4.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EMC98317.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif CTDII PF01556.13 EMC98317.1 - 0.052 13.4 9.2 5 7.0 0.2 3.4 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 EMC98317.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase FERM_N PF09379.5 EMC98317.1 - 0.092 12.8 8.6 28 4.8 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 EMC98317.1 - 0.29 11.1 3.6 70 3.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 EMC98317.1 - 3.3 7.4 7.5 46 3.7 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 KID PF02524.9 EMC98317.1 - 6.8 7.2 8.1 2.1e+02 2.8 0.1 4.8 3 0 0 3 3 3 0 KID repeat Methyltransf_23 PF13489.1 EMC98318.1 - 2.6e-18 66.2 0.0 4.2e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC98318.1 - 2.2e-10 41.0 0.0 4.8e-09 36.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC98318.1 - 1.3e-09 38.4 0.0 5.1e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC98318.1 - 8.6e-08 32.5 0.0 1e-06 29.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC98318.1 - 2e-07 30.7 0.0 2.3e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC98318.1 - 0.00027 20.0 0.0 0.00094 18.2 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EMC98318.1 - 0.0013 19.0 0.0 0.0037 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC98318.1 - 0.0022 18.0 0.0 0.006 16.5 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 EMC98318.1 - 0.016 14.5 0.0 0.048 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EMC98318.1 - 0.053 12.6 0.0 0.18 10.8 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EMC98318.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase p450 PF00067.17 EMC98319.1 - 1.6e-41 142.2 0.0 2.3e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.17 EMC98320.1 - 5e-77 259.8 0.3 1.7e-76 258.0 0.2 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Transket_pyr PF02779.19 EMC98322.1 - 2.2e-62 209.7 0.0 3.6e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EMC98322.1 - 7.1e-61 205.5 0.0 9.9e-61 205.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_81 PF03639.8 EMC98323.1 - 3.3e-199 663.3 7.6 3.8e-199 663.1 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 GCFC PF07842.7 EMC98326.1 - 4e-74 249.4 3.6 4e-74 249.4 2.5 1.7 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EMC98326.1 - 8.8e-17 60.6 3.9 2e-16 59.4 2.7 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC98326.1 - 1.1e-07 31.5 0.8 4.3e-07 29.6 0.6 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site Inositol_P PF00459.20 EMC98329.1 - 2.6e-10 40.0 0.0 2.9e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.6 EMC98330.1 - 2.3e-22 78.8 0.0 4.5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMC98330.1 - 5.2e-11 42.7 0.0 7.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EMC98331.1 - 1e-125 419.8 28.5 1.2e-125 419.6 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC98331.1 - 8.9e-20 70.6 42.7 8.9e-20 70.6 29.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 EMC98332.1 - 1.3e-27 96.6 0.1 1.9e-27 96.1 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMC98332.1 - 1.9e-12 46.9 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.14 EMC98332.1 - 0.046 14.2 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain AP_endonuc_2 PF01261.19 EMC98333.1 - 2.3e-28 98.9 0.0 3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel NAD_binding_11 PF14833.1 EMC98333.1 - 0.09 12.8 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.17 EMC98334.1 - 5e-79 259.9 4.6 1.6e-21 75.6 0.2 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC98334.1 - 1.5e-52 175.4 0.4 1.2e-12 47.6 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC98334.1 - 3.3e-38 129.3 0.3 1.9e-08 34.0 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EMC98334.1 - 1e-29 101.9 1.8 3.5e-29 100.2 0.3 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EMC98334.1 - 1.8e-05 24.4 1.5 0.55 10.0 0.1 3.7 4 0 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 EMC98334.1 - 8.5e-05 22.2 0.2 7.5 6.4 0.0 4.6 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EMC98334.1 - 0.0001 22.5 0.0 0.23 11.7 0.0 3.6 3 0 0 3 3 3 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 EMC98334.1 - 0.0087 15.5 0.7 10 5.6 0.0 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain SseC PF04888.7 EMC98335.1 - 0.069 12.4 2.6 0.075 12.3 1.8 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Chlorosome_CsmC PF11098.3 EMC98335.1 - 0.12 12.0 7.3 0.15 11.7 5.1 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Bacteriocin_IIc PF10439.4 EMC98335.1 - 8.5 6.5 15.9 10 6.3 10.0 1.8 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide EF-hand_7 PF13499.1 EMC98336.1 - 2.6e-18 65.9 0.9 9.5e-10 38.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC98336.1 - 4.7e-18 63.0 4.5 9.8e-08 30.7 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EMC98336.1 - 3.9e-15 54.3 5.5 1.4e-07 30.8 0.1 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EMC98336.1 - 5.5e-13 48.3 2.7 1.4e-06 27.7 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC98336.1 - 7.6e-08 31.3 5.5 0.0004 19.5 0.0 3.2 3 1 1 4 4 4 2 EF hand EF-hand_9 PF14658.1 EMC98336.1 - 2.9e-05 23.8 0.0 0.00036 20.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 EMC98336.1 - 0.00072 19.2 0.1 0.037 13.7 0.0 2.3 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Methyltransf_3 PF01596.12 EMC98336.1 - 0.05 12.6 0.1 0.077 12.0 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase TerB PF05099.8 EMC98336.1 - 0.41 10.3 4.1 0.82 9.3 0.3 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TerB MAT_Alpha1 PF04769.7 EMC98339.1 - 0.00095 18.5 0.0 0.001 18.4 0.0 1.0 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Pro_CA PF00484.14 EMC98341.1 - 1.5e-42 145.1 0.0 2.1e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Velvet PF11754.3 EMC98343.1 - 1.3e-35 122.8 0.2 2.3e-34 118.8 0.1 2.1 1 1 0 1 1 1 1 Velvet factor Uds1 PF15456.1 EMC98344.1 - 2.8e-31 108.0 1.1 2.8e-31 108.0 0.8 8.8 3 2 5 8 8 8 2 Up-regulated During Septation RBD PF02196.10 EMC98344.1 - 0.0062 16.2 0.7 3.3 7.5 0.0 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain Aminotran_1_2 PF00155.16 EMC98345.1 - 0.047 12.6 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_1_2 PF00155.16 EMC98346.1 - 7.2e-08 31.7 0.0 7.6e-08 31.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HIG_1_N PF04588.8 EMC98348.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Hypoxia induced protein conserved region MOZ_SAS PF01853.13 EMC98349.1 - 1.7e-67 226.3 0.2 3.4e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family PHD PF00628.24 EMC98349.1 - 0.0015 18.2 4.3 0.0015 18.2 3.0 2.3 2 0 0 2 2 2 1 PHD-finger V_ATPase_I PF01496.14 EMC98350.1 - 3.6e-295 980.7 0.0 4.2e-295 980.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Serine_rich PF08824.5 EMC98350.1 - 0.0038 16.9 0.7 0.0061 16.2 0.1 1.6 2 0 0 2 2 2 1 Serine rich protein interaction domain Filament PF00038.16 EMC98350.1 - 0.0047 16.4 3.8 0.19 11.1 0.3 2.2 2 0 0 2 2 2 2 Intermediate filament protein CheZ PF04344.8 EMC98350.1 - 0.012 15.2 2.4 0.02 14.5 0.2 2.1 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ TBPIP PF07106.8 EMC98350.1 - 0.23 10.9 2.3 2.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 EMC98350.1 - 0.31 10.5 1.9 0.69 9.4 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.7 EMC98350.1 - 0.34 10.7 2.2 2.9 7.7 0.0 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EMC98350.1 - 0.45 10.3 2.4 3.4 7.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HWE_HK PF07536.9 EMC98350.1 - 1.2 9.6 5.4 1.1 9.7 0.1 3.0 3 0 0 3 3 3 0 HWE histidine kinase HR1 PF02185.11 EMC98350.1 - 2 8.2 4.9 4.8 7.0 0.1 3.0 3 0 0 3 3 3 0 Hr1 repeat Aa_trans PF01490.13 EMC98352.1 - 1.8e-71 240.7 25.9 2.3e-71 240.4 17.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMC98352.1 - 2.9e-06 26.1 26.4 2.9e-06 26.1 18.3 1.6 1 1 1 2 2 2 1 Amino acid permease PBP PF01161.15 EMC98355.1 - 1.8e-08 34.3 0.1 2.9e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein YTH PF04146.10 EMC98356.1 - 1.6e-34 118.4 0.0 1.8e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 YT521-B-like domain NifQ PF04891.7 EMC98357.1 - 0.045 13.8 3.2 0.091 12.9 0.4 2.3 2 0 0 2 2 2 0 NifQ Mnd1 PF03962.10 EMC98357.1 - 0.5 9.9 6.2 3.4 7.3 0.3 2.4 2 0 0 2 2 2 0 Mnd1 family Nramp PF01566.13 EMC98358.1 - 4.2e-83 279.0 18.2 4.2e-83 279.0 12.6 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Mannosyl_trans2 PF04188.8 EMC98360.1 - 2.9e-62 211.0 11.9 3.7e-62 210.6 8.3 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) PHD PF00628.24 EMC98361.1 - 2.8e-10 39.7 8.3 3.2e-10 39.5 5.8 1.1 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EMC98361.1 - 0.035 14.2 4.9 0.047 13.8 3.4 1.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 EMC98361.1 - 0.062 13.2 2.7 0.073 13.0 1.9 1.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EMC98361.1 - 0.13 12.2 2.5 0.16 11.9 1.7 1.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain Peptidase_M41 PF01434.13 EMC98362.1 - 2.9e-68 229.5 2.3 4.6e-68 228.8 1.6 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMC98362.1 - 4.4e-44 149.8 0.0 1.4e-43 148.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC98362.1 - 1.6e-06 27.9 0.0 5.5e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC98362.1 - 5.4e-06 26.5 1.3 0.00022 21.2 0.9 3.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EMC98362.1 - 1.7e-05 25.6 0.0 4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC98362.1 - 2.3e-05 24.5 1.6 0.0026 17.8 0.1 3.1 3 1 0 3 3 1 1 AAA domain TIP49 PF06068.8 EMC98362.1 - 3.8e-05 22.5 0.0 7.5e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EMC98362.1 - 0.00012 21.1 0.0 0.00024 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EMC98362.1 - 0.00068 19.0 1.7 0.057 12.8 0.3 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMC98362.1 - 0.0015 18.0 0.1 0.0051 16.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMC98362.1 - 0.0015 18.2 1.9 0.0043 16.7 0.2 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EMC98362.1 - 0.002 18.0 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC98362.1 - 0.0051 15.9 0.8 0.016 14.2 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin FadA PF09403.5 EMC98362.1 - 0.0079 16.2 2.3 0.24 11.4 0.0 2.5 2 0 0 2 2 2 1 Adhesion protein FadA AAA_2 PF07724.9 EMC98362.1 - 0.0083 16.0 0.0 0.045 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EMC98362.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC98362.1 - 0.015 15.6 0.0 0.13 12.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 EMC98362.1 - 0.016 14.3 0.2 0.037 13.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMC98362.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC98362.1 - 0.054 13.1 0.3 1 8.9 0.1 2.4 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EMC98362.1 - 0.065 12.3 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EMC98362.1 - 0.1 11.8 0.6 0.25 10.5 0.2 1.8 2 0 0 2 2 2 0 PhoH-like protein COesterase PF00135.23 EMC98363.1 - 4.1e-62 210.6 0.0 5.6e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC98363.1 - 4e-11 42.8 0.0 3.9e-10 39.6 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC98363.1 - 0.00035 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EMC98363.1 - 0.0037 16.6 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EMC98363.1 - 0.0037 17.1 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC98363.1 - 0.005 16.0 0.0 0.016 14.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EMC98363.1 - 0.036 12.7 0.0 0.11 11.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) zf-H2C2_2 PF13465.1 EMC98366.1 - 3e-21 74.5 24.7 2.7e-07 30.5 0.7 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC98366.1 - 1.1e-20 72.6 24.7 2.3e-05 24.4 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC98366.1 - 1e-14 53.6 27.5 0.00024 21.1 2.6 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC98366.1 - 0.00089 19.3 12.9 2.8 8.1 0.0 5.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC98366.1 - 0.0037 17.4 13.8 4.6 7.5 0.5 5.0 5 0 0 5 5 5 2 Zinc-finger of C2H2 type XPA_N PF01286.13 EMC98366.1 - 0.064 12.9 6.7 0.078 12.6 0.2 3.0 3 0 0 3 3 3 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EMC98366.1 - 0.086 12.8 8.9 14 5.7 0.0 3.6 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMC98366.1 - 0.13 12.1 16.8 1.3 9.0 0.8 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-TRAF PF02176.13 EMC98366.1 - 0.16 12.3 8.3 1.1 9.7 0.5 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger C1_4 PF07975.7 EMC98366.1 - 0.88 9.6 3.5 20 5.2 0.0 3.0 1 1 1 2 2 2 0 TFIIH C1-like domain LIM PF00412.17 EMC98366.1 - 1.3 9.1 4.8 37 4.4 0.1 3.1 2 1 1 3 3 3 0 LIM domain C1_1 PF00130.17 EMC98366.1 - 1.3 8.7 5.1 0.89 9.3 0.7 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DHBP_synthase PF00926.14 EMC98369.1 - 2.2e-71 239.1 0.0 9.9e-71 236.9 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF501 PF04417.7 EMC98369.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF501) MFS_1 PF07690.11 EMC98370.1 - 1.6e-30 106.0 28.5 1.6e-30 106.0 19.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98370.1 - 3.4e-08 32.4 5.6 3.4e-08 32.4 3.9 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter RRM_1 PF00076.17 EMC98374.1 - 3.9e-16 58.4 0.1 3.1e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC98374.1 - 3.2e-09 36.6 0.0 2.6e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Aida_C2 PF14186.1 EMC98374.1 - 0.12 11.5 0.7 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Cytoskeletal adhesion MFS_1 PF07690.11 EMC98375.1 - 9.3e-19 67.3 37.0 9.3e-19 67.3 25.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98375.1 - 1.2e-10 40.6 24.7 2.1e-09 36.4 17.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter SpoVAB PF13782.1 EMC98375.1 - 0.015 15.3 0.3 0.051 13.5 0.2 2.0 1 0 0 1 1 1 0 Stage V sporulation protein AB TIP120 PF08623.5 EMC98376.1 - 2.8e-60 202.7 0.1 2.3e-58 196.5 0.0 3.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EMC98376.1 - 3e-17 61.0 4.9 0.26 11.4 0.0 11.4 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.1 EMC98376.1 - 6.8e-13 48.7 20.2 0.11 12.8 0.0 9.3 9 2 1 11 11 11 6 HEAT repeats HEAT_EZ PF13513.1 EMC98376.1 - 5.3e-08 33.1 22.5 5.7 7.5 0.0 12.9 13 2 1 14 14 14 2 HEAT-like repeat Adaptin_N PF01602.15 EMC98376.1 - 3.7e-07 28.8 1.2 0.044 12.1 0.0 6.2 4 3 1 6 6 6 1 Adaptin N terminal region DUF2435 PF10363.4 EMC98376.1 - 4e-05 23.4 3.1 1.6 8.6 0.0 5.0 4 1 0 4 4 4 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EMC98376.1 - 0.00031 20.1 0.5 8.2 5.7 0.1 4.9 5 0 0 5 5 5 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 EMC98376.1 - 0.0023 18.2 0.9 3.5 8.0 0.0 5.0 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region DUF3554 PF12074.3 EMC98376.1 - 0.012 15.0 1.2 0.11 11.9 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3554) MMS19_C PF12460.3 EMC98376.1 - 0.016 13.9 5.7 20 3.7 0.0 5.2 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal bZIP_1 PF00170.16 EMC98379.1 - 8.6e-10 38.4 13.2 1.3e-09 37.8 9.2 1.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC98379.1 - 4.7e-09 35.9 13.1 6e-09 35.5 9.1 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC98379.1 - 3.2e-05 24.1 9.4 3.9e-05 23.8 6.5 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 EMC98379.1 - 0.044 12.9 3.3 0.048 12.8 2.3 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TSC22 PF01166.13 EMC98379.1 - 0.046 13.6 1.0 0.086 12.8 0.7 1.5 1 1 0 1 1 1 0 TSC-22/dip/bun family Wbp11 PF09429.5 EMC98379.1 - 0.056 13.4 8.3 0.064 13.2 5.8 1.1 1 0 0 1 1 1 0 WW domain binding protein 11 DUF1202 PF06717.6 EMC98379.1 - 0.075 12.2 0.6 0.086 12.1 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DUF3020 PF11223.3 EMC98379.1 - 0.14 12.6 3.5 0.19 12.1 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) MAT1 PF06391.8 EMC98379.1 - 0.14 11.7 5.2 0.14 11.6 3.6 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 HAP1_N PF04849.8 EMC98379.1 - 0.2 10.5 4.7 0.22 10.4 3.3 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region M PF02370.11 EMC98379.1 - 0.31 11.5 0.8 0.31 11.5 0.5 2.4 3 0 0 3 3 3 0 M protein repeat DUF904 PF06005.7 EMC98379.1 - 0.6 10.4 4.5 0.82 9.9 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 EMC98379.1 - 0.71 9.6 5.9 0.27 10.9 1.4 1.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper Sec2p PF06428.6 EMC98380.1 - 1.9e-11 43.6 8.8 1.9e-11 43.6 6.1 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 EMC98380.1 - 0.0013 18.4 13.6 0.026 14.0 3.0 2.4 2 0 0 2 2 2 2 IncA protein MbeD_MobD PF04899.7 EMC98380.1 - 0.0087 15.9 0.8 0.0087 15.9 0.6 3.7 2 2 1 3 3 3 1 MbeD/MobD like CENP-F_leu_zip PF10473.4 EMC98380.1 - 0.013 15.3 28.2 0.024 14.5 10.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSBP1 PF06825.7 EMC98380.1 - 0.015 14.8 3.2 0.016 14.7 0.2 2.5 3 0 0 3 3 2 0 Heat shock factor binding protein 1 Spc24 PF08286.6 EMC98380.1 - 0.016 14.8 3.9 0.016 14.8 2.7 3.2 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 EMC98380.1 - 0.02 14.3 3.2 0.02 14.3 2.2 4.1 3 2 1 4 4 4 0 Septum formation initiator Myosin_tail_1 PF01576.14 EMC98380.1 - 0.022 12.4 33.8 0.069 10.8 3.9 2.9 2 1 1 3 3 3 0 Myosin tail Leu_zip PF15294.1 EMC98380.1 - 0.022 13.8 0.6 0.022 13.8 0.4 2.5 2 1 0 2 2 2 0 Leucine zipper Effector_1 PF04518.7 EMC98380.1 - 0.023 13.7 0.7 0.023 13.7 0.5 1.9 2 0 0 2 2 2 0 Effector from type III secretion system Prefoldin_2 PF01920.15 EMC98380.1 - 0.031 14.0 0.5 0.031 14.0 0.3 3.7 3 1 1 4 4 4 0 Prefoldin subunit Reo_sigmaC PF04582.7 EMC98380.1 - 0.037 13.2 0.9 0.21 10.7 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 EMC98380.1 - 0.05 13.9 1.8 0.05 13.9 1.3 3.6 3 2 0 3 3 3 0 SlyX DUF3113 PF11310.3 EMC98380.1 - 0.062 12.9 0.4 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) TBPIP PF07106.8 EMC98380.1 - 0.066 12.7 18.2 0.25 10.8 4.7 2.8 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlxA PF14282.1 EMC98380.1 - 0.069 13.0 12.7 1.1 9.2 0.7 2.9 3 1 0 3 3 3 0 FlxA-like protein bZIP_1 PF00170.16 EMC98380.1 - 0.077 12.9 1.0 0.077 12.9 0.7 4.7 4 2 0 4 4 3 0 bZIP transcription factor BRE1 PF08647.6 EMC98380.1 - 0.089 12.7 14.5 0.091 12.7 0.8 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_23 PF13476.1 EMC98380.1 - 0.11 12.8 9.6 0.76 10.0 0.9 2.3 2 0 0 2 2 2 0 AAA domain DALR_1 PF05746.10 EMC98380.1 - 0.19 11.6 3.9 0.12 12.3 0.5 2.1 2 1 0 2 2 2 0 DALR anticodon binding domain DUF1664 PF07889.7 EMC98380.1 - 0.23 11.2 7.7 5.4 6.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 EMC98380.1 - 0.27 10.6 15.2 0.39 10.1 4.5 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 GAS PF13851.1 EMC98380.1 - 0.29 10.2 25.1 0.16 11.1 3.1 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 EMC98380.1 - 0.38 10.6 19.5 0.054 13.3 2.6 3.8 4 1 1 5 5 3 0 Flagella accessory protein C (FlaC) HSCB_C PF07743.8 EMC98380.1 - 0.38 11.2 0.2 0.38 11.2 0.1 4.0 2 2 1 3 3 3 0 HSCB C-terminal oligomerisation domain DivIVA PF05103.8 EMC98380.1 - 0.4 10.7 24.5 0.16 12.0 1.7 3.8 2 1 2 4 4 4 0 DivIVA protein DUF4515 PF14988.1 EMC98380.1 - 0.41 10.2 23.5 0.29 10.7 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) DUF972 PF06156.8 EMC98380.1 - 0.56 10.5 15.7 2.4 8.5 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 EMC98380.1 - 0.56 10.0 4.9 0.27 11.0 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SPT16 PF08644.6 EMC98380.1 - 0.69 9.7 7.4 0.042 13.6 1.1 1.9 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) ATG16 PF08614.6 EMC98380.1 - 0.73 9.6 24.1 1.4 8.6 6.6 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF2937 PF11157.3 EMC98380.1 - 0.9 8.8 9.1 2.5 7.3 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) ADIP PF11559.3 EMC98380.1 - 1 9.2 24.2 1.3 8.8 3.7 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Osmo_CC PF08946.5 EMC98380.1 - 1.3 9.1 15.6 0.82 9.7 0.4 4.0 2 2 2 4 4 4 0 Osmosensory transporter coiled coil Striatin PF08232.7 EMC98380.1 - 1.4 9.2 20.4 1.1 9.5 0.3 3.7 2 1 1 3 3 3 0 Striatin family Spc7 PF08317.6 EMC98380.1 - 1.5 7.3 18.6 0.52 8.9 0.8 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein CDC37_N PF03234.9 EMC98380.1 - 1.6 8.9 13.5 0.78 10.0 5.5 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding NPV_P10 PF05531.7 EMC98380.1 - 1.9 8.8 10.6 17 5.7 1.3 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Miff PF05644.6 EMC98380.1 - 1.9 8.0 11.0 6.6 6.2 7.6 1.9 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF4618 PF15397.1 EMC98380.1 - 1.9 7.7 14.2 4.2 6.6 4.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF1798 PF08807.5 EMC98380.1 - 2.5 7.8 6.4 2.6 7.8 0.7 2.4 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) KIAA1430 PF13879.1 EMC98380.1 - 2.7 8.4 12.4 0.16 12.4 0.9 3.0 2 1 1 3 3 3 0 KIAA1430 homologue Tropomyosin_1 PF12718.2 EMC98380.1 - 3.1 7.6 30.1 0.8 9.5 3.3 2.5 2 1 0 2 2 2 0 Tropomyosin like GCN5L1 PF06320.8 EMC98380.1 - 5.4 6.8 11.7 1.2 8.9 1.4 2.9 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) HAUS-augmin3 PF14932.1 EMC98380.1 - 5.9 5.9 20.9 1.5 7.9 1.9 2.7 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Prominin PF05478.6 EMC98380.1 - 7.1 4.0 5.9 1.1 6.7 0.4 1.9 2 0 0 2 2 2 0 Prominin KxDL PF10241.4 EMC98380.1 - 9.3 6.2 12.0 3.7 7.5 1.9 2.7 3 0 0 3 3 2 0 Uncharacterized conserved protein TRAM_LAG1_CLN8 PF03798.11 EMC98382.1 - 1.2e-35 122.8 22.7 1.2e-35 122.8 15.7 1.9 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EMC98382.1 - 1.5e-17 62.7 1.3 4.8e-17 61.2 0.0 2.4 2 0 0 2 2 2 1 TRAM1-like protein F_bP_aldolase PF01116.15 EMC98383.1 - 2.5e-101 338.5 0.0 2.8e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DAG_kinase_N PF14513.1 EMC98383.1 - 0.063 13.4 0.8 0.55 10.4 0.1 2.4 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus Prp19 PF08606.6 EMC98384.1 - 7.5e-31 105.6 2.4 1.7e-30 104.5 1.6 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EMC98384.1 - 3.3e-15 55.2 11.2 0.00026 20.7 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3312 PF11768.3 EMC98384.1 - 0.0014 16.9 0.0 0.0026 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) U-box PF04564.10 EMC98384.1 - 0.026 14.4 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain Cytochrom_D1 PF02239.11 EMC98384.1 - 0.039 12.2 0.0 0.067 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain zf-Nse PF11789.3 EMC98384.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CPSF_A PF03178.10 EMC98384.1 - 0.091 11.8 0.0 1.2 8.1 0.0 2.4 2 1 1 3 3 3 0 CPSF A subunit region FliT PF05400.8 EMC98384.1 - 0.36 11.2 7.4 0.059 13.7 1.2 2.1 1 1 1 2 2 2 0 Flagellar protein FliT zf-RING_5 PF14634.1 EMC98385.1 - 0.0004 20.0 0.7 0.00072 19.2 0.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC98385.1 - 0.0016 18.0 0.6 0.0036 16.9 0.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC98385.1 - 0.0022 17.9 3.2 0.0075 16.2 2.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC98385.1 - 0.0042 16.8 0.8 0.0076 16.0 0.6 1.4 1 0 0 1 1 1 1 Ring finger domain FYVE PF01363.16 EMC98385.1 - 0.18 11.7 3.8 0.39 10.6 2.6 1.5 1 1 0 1 1 1 0 FYVE zinc finger zf-ribbon_3 PF13248.1 EMC98385.1 - 1.9 7.8 6.2 0.65 9.2 1.9 2.0 2 1 0 2 2 2 0 zinc-ribbon domain PX PF00787.19 EMC98386.1 - 5.7e-17 61.5 0.2 1.3e-16 60.4 0.2 1.6 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.4 EMC98386.1 - 0.078 11.5 0.3 0.16 10.5 0.2 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PTPLA PF04387.9 EMC98387.1 - 1.8e-50 170.5 11.8 3.3e-50 169.7 8.2 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Aha1_N PF09229.6 EMC98388.1 - 4.6e-38 130.1 0.2 7.5e-38 129.4 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EMC98388.1 - 4.2e-17 62.4 0.2 9e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.3 EMC98388.1 - 0.053 12.6 1.4 0.069 12.2 1.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Ras PF00071.17 EMC98390.1 - 8.1e-32 109.8 0.2 1e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC98390.1 - 1.3e-20 74.0 0.1 5.5e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC98390.1 - 5.8e-07 28.9 0.1 7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC98390.1 - 6.7e-06 25.4 0.2 8.7e-06 25.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC98390.1 - 0.048 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.6 EMC98390.1 - 0.071 11.7 0.3 3.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 EMC98390.1 - 0.13 10.9 3.9 0.15 10.7 0.0 2.5 1 1 2 3 3 3 0 G-protein alpha subunit Kinetochor_Ybp2 PF08568.5 EMC98391.1 - 2.2e-119 399.5 0.0 2.7e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin MFS_1 PF07690.11 EMC98393.1 - 5.8e-26 91.0 86.6 1.5e-22 79.7 33.9 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMC98393.1 - 1.2e-08 33.6 18.3 1.6e-08 33.2 12.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMC98393.1 - 0.00037 19.2 4.2 0.00037 19.2 2.9 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter ADH_N PF08240.7 EMC98394.1 - 8.7e-19 67.2 0.2 1.6e-18 66.4 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box PF00646.28 EMC98395.1 - 6.1e-06 25.7 0.7 1.5e-05 24.4 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC98395.1 - 1.9e-05 24.2 0.4 5.1e-05 22.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like Raptor_N PF14538.1 EMC98396.1 - 1.4e-59 200.3 0.0 2.5e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EMC98396.1 - 6.9e-13 47.9 0.1 0.017 14.9 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMC98396.1 - 2.5e-05 24.0 0.6 0.011 15.4 0.0 3.3 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 EMC98396.1 - 0.00027 20.7 5.5 0.16 12.1 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat Peptidase_C14 PF00656.17 EMC98396.1 - 0.00097 18.9 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Atx10homo_assoc PF09759.4 EMC98396.1 - 0.0031 17.2 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain SIN1 PF05422.7 EMC98401.1 - 4.8e-26 91.3 0.0 2.3e-16 59.4 0.0 3.1 3 0 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) CM_1 PF07736.6 EMC98401.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Chorismate mutase type I adh_short PF00106.20 EMC98402.1 - 1.4e-12 47.8 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC98402.1 - 4e-09 36.3 0.0 7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Imm34 PF15596.1 EMC98402.1 - 0.036 14.2 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 34 AAA_13 PF13166.1 EMC98403.1 - 0.00025 19.6 0.1 0.00033 19.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain FlaC_arch PF05377.6 EMC98403.1 - 0.00095 19.0 4.0 0.14 12.0 0.1 2.7 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) Atg14 PF10186.4 EMC98403.1 - 0.0013 17.7 6.0 0.19 10.6 0.3 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EMC98403.1 - 0.0017 17.9 6.4 0.16 11.4 0.3 2.2 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG2 PF06148.6 EMC98403.1 - 0.0025 17.6 3.3 0.075 12.9 0.3 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.6 EMC98403.1 - 0.0029 17.4 8.9 0.039 13.7 0.4 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 EMC98403.1 - 0.0042 17.1 3.7 0.12 12.5 0.4 2.3 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 EMC98403.1 - 0.011 15.5 10.6 0.27 11.0 1.9 2.2 1 1 1 2 2 2 0 Tropomyosin like MscS_porin PF12795.2 EMC98403.1 - 0.012 14.9 15.4 0.022 14.0 9.1 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain NPV_P10 PF05531.7 EMC98403.1 - 0.013 15.7 1.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EMC98403.1 - 0.042 13.5 10.8 0.73 9.5 0.6 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 EMC98403.1 - 0.049 13.3 10.3 0.23 11.2 0.3 3.2 2 1 1 3 3 3 0 Prefoldin subunit Phage_GP20 PF06810.6 EMC98403.1 - 0.063 12.7 6.7 0.55 9.6 1.1 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 USP8_interact PF08941.5 EMC98403.1 - 0.064 12.5 0.6 2.6 7.3 0.1 2.2 2 0 0 2 2 2 0 USP8 interacting IncA PF04156.9 EMC98403.1 - 0.066 12.8 18.4 0.58 9.7 12.9 2.0 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.6 EMC98403.1 - 0.083 11.5 9.8 0.4 9.3 6.7 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 EMC98403.1 - 0.083 12.6 4.7 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 EMC98403.1 - 0.086 12.0 0.3 7.9 5.5 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 EMC98403.1 - 0.11 11.9 12.6 0.53 9.7 2.2 3.0 2 1 0 2 2 2 0 Septum formation initiator COG5 PF10392.4 EMC98403.1 - 0.12 12.3 2.2 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Med9 PF07544.8 EMC98403.1 - 0.13 11.9 10.8 0.25 11.1 0.5 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4201 PF13870.1 EMC98403.1 - 0.21 11.0 7.1 4.3 6.7 4.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Prefoldin PF02996.12 EMC98403.1 - 0.24 11.0 8.5 5.2 6.7 0.2 3.2 1 1 2 3 3 3 0 Prefoldin subunit DUF1192 PF06698.6 EMC98403.1 - 0.3 10.9 7.9 0.84 9.4 0.1 3.4 3 1 0 3 3 2 0 Protein of unknown function (DUF1192) DUF812 PF05667.6 EMC98403.1 - 0.3 9.5 11.0 0.062 11.8 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Fib_alpha PF08702.5 EMC98403.1 - 0.33 11.0 4.3 2.1 8.4 2.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.5 EMC98403.1 - 0.44 10.6 8.7 0.29 11.1 0.2 3.6 3 1 1 4 4 4 0 Osmosensory transporter coiled coil IFT57 PF10498.4 EMC98403.1 - 0.46 9.1 4.7 3 6.4 0.2 2.3 3 0 0 3 3 2 0 Intra-flagellar transport protein 57 DUF972 PF06156.8 EMC98403.1 - 0.47 10.8 4.7 1.9 8.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF16 PF01519.11 EMC98403.1 - 0.48 10.6 4.3 3.2 8.0 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF16 FlxA PF14282.1 EMC98403.1 - 0.51 10.3 9.2 0.91 9.5 2.4 2.4 2 0 0 2 2 2 0 FlxA-like protein ERM PF00769.14 EMC98403.1 - 0.57 9.6 13.4 6.2 6.2 9.3 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CCDC155 PF14662.1 EMC98403.1 - 0.57 9.7 13.7 0.28 10.7 1.6 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 ADIP PF11559.3 EMC98403.1 - 0.61 9.9 13.6 0.34 10.8 1.9 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding End3 PF12761.2 EMC98403.1 - 0.66 9.5 5.3 1 9.0 3.7 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3552 PF12072.3 EMC98403.1 - 0.78 8.9 14.0 1 8.5 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) DUF904 PF06005.7 EMC98403.1 - 0.88 9.9 11.1 0.25 11.6 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF904) LCD1 PF09798.4 EMC98403.1 - 0.98 7.3 4.8 1.3 6.9 3.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Syntaxin PF00804.20 EMC98403.1 - 0.98 9.6 5.3 5.7 7.1 3.7 2.1 1 1 0 1 1 1 0 Syntaxin Baculo_PEP_C PF04513.7 EMC98403.1 - 1 9.1 4.1 14 5.4 2.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uds1 PF15456.1 EMC98403.1 - 1.1 9.2 6.4 5.4 7.0 4.4 2.2 1 1 0 1 1 1 0 Up-regulated During Septation CCDC92 PF14916.1 EMC98403.1 - 1.1 8.8 4.4 0.57 9.8 0.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Mod_r PF07200.8 EMC98403.1 - 1.1 9.1 8.8 6.5 6.6 2.3 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 EMC98403.1 - 1.2 8.3 11.4 1.7 7.7 1.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.10 EMC98403.1 - 1.5 8.8 12.8 1.7 8.6 7.4 1.8 1 1 1 2 2 2 0 Fez1 Viral_P18 PF04521.8 EMC98403.1 - 1.9 7.9 7.2 2.5 7.5 0.1 2.7 1 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4200 PF13863.1 EMC98403.1 - 2 8.4 18.3 0.76 9.7 1.5 3.0 3 1 0 3 3 2 0 Domain of unknown function (DUF4200) MerR-DNA-bind PF09278.6 EMC98403.1 - 2.1 8.7 13.4 7 7.1 1.4 3.2 2 2 0 2 2 2 0 MerR, DNA binding DUF342 PF03961.8 EMC98403.1 - 2.4 6.4 4.4 5.8 5.2 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 EMC98403.1 - 2.7 7.8 15.1 4.5 7.1 2.2 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.1 EMC98403.1 - 3.9 6.3 7.6 8.1 5.3 5.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.6 EMC98403.1 - 4.6 7.2 7.6 0.7 9.8 0.9 2.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3584 PF12128.3 EMC98403.1 - 4.7 4.4 14.4 0.89 6.7 3.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) Snapin_Pallidin PF14712.1 EMC98403.1 - 6.8 7.0 7.8 6.3 7.1 1.9 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Ax_dynein_light PF10211.4 EMC98403.1 - 7.4 6.3 11.1 10 5.9 2.0 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Macoilin PF09726.4 EMC98403.1 - 7.5 4.7 6.5 18 3.4 4.5 1.6 1 1 0 1 1 1 0 Transmembrane protein Lge1 PF11488.3 EMC98403.1 - 8.6 6.6 6.8 1.6e+02 2.5 4.7 2.6 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 PHD PF00628.24 EMC98405.1 - 1e-05 25.0 13.5 1e-05 25.0 9.3 2.1 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 EMC98405.1 - 0.016 15.3 6.5 0.034 14.2 4.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Lipase_GDSL PF00657.17 EMC98407.1 - 1.3e-13 51.3 1.0 5.2e-13 49.3 0.8 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMC98407.1 - 6.5e-12 45.9 1.2 1.2e-11 45.0 0.8 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ribosomal_L37e PF01907.14 EMC98408.1 - 7.3e-25 86.5 12.9 1.2e-24 85.8 8.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EMC98408.1 - 0.0009 19.0 1.8 0.0014 18.3 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EMC98408.1 - 0.031 13.5 4.1 0.11 11.6 2.8 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 EMC98408.1 - 0.046 13.5 2.2 0.065 13.0 1.5 1.2 1 0 0 1 1 1 0 Zinc-ribbon HypA PF01155.14 EMC98408.1 - 0.063 12.9 1.1 0.083 12.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EMC98408.1 - 0.12 11.9 5.1 2.5 7.7 3.6 2.2 1 1 1 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EMC98408.1 - 0.15 11.9 4.8 3.7 7.5 3.2 2.3 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-FPG_IleRS PF06827.9 EMC98408.1 - 0.19 11.4 3.8 0.4 10.3 2.6 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS OrfB_Zn_ribbon PF07282.6 EMC98408.1 - 0.26 10.9 3.5 0.45 10.2 2.4 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ISL3 PF14690.1 EMC98408.1 - 2.3 8.3 7.6 4.4 7.4 0.7 2.4 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 GST_N_2 PF13409.1 EMC98409.1 - 7e-21 74.0 0.0 1.5e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC98409.1 - 5.5e-12 45.3 0.0 2.2e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC98409.1 - 2.5e-07 31.0 0.0 4.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC98409.1 - 1e-05 25.4 0.2 3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC98409.1 - 0.004 17.3 0.0 0.061 13.5 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BPL_LplA_LipB PF03099.14 EMC98410.1 - 2.3e-13 50.2 0.1 3.6e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rpp20 PF12328.3 EMC98411.1 - 5.1e-32 110.5 9.7 5.9e-31 107.0 6.7 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EMC98411.1 - 7.5e-17 60.6 0.1 1.5e-16 59.6 0.1 1.6 1 1 0 1 1 1 1 Alba PX PF00787.19 EMC98412.1 - 5.9e-24 84.0 0.0 7.3e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 PX domain WD40 PF00400.27 EMC98413.1 - 2.4e-14 52.5 11.8 1.9e-06 27.4 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3312 PF11768.3 EMC98413.1 - 0.0001 20.6 0.3 0.0027 16.0 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 EMC98413.1 - 0.00031 20.2 3.9 0.38 10.1 0.3 3.2 2 1 1 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.6 EMC98413.1 - 0.0018 17.1 0.2 0.044 12.5 0.2 2.6 1 1 0 1 1 1 1 Nup133 N terminal like PQQ_3 PF13570.1 EMC98413.1 - 0.0029 17.8 0.4 41 4.6 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain Nup160 PF11715.3 EMC98413.1 - 0.04 12.0 10.4 0.68 7.9 0.5 3.1 1 1 2 3 3 3 0 Nucleoporin Nup120/160 UBX PF00789.15 EMC98415.1 - 6.6e-08 32.5 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain Borrelia_P83 PF05262.6 EMC98415.1 - 0.0039 15.5 10.1 0.0061 14.8 7.0 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein CAF-1_p150 PF11600.3 EMC98415.1 - 0.82 9.0 29.9 0.54 9.5 18.7 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 EMC98415.1 - 3 5.4 6.0 3.6 5.1 4.2 1.1 1 0 0 1 1 1 0 Ycf1 SURF1 PF02104.10 EMC98416.1 - 8.9e-63 211.9 0.5 1.3e-62 211.4 0.1 1.4 2 0 0 2 2 2 1 SURF1 family YozD PF14162.1 EMC98416.1 - 0.2 11.7 0.0 0.52 10.4 0.0 1.6 2 0 0 2 2 2 0 YozD-like protein PCI PF01399.22 EMC98417.1 - 7.7e-19 67.9 0.0 1.7e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain CMS1 PF14617.1 EMC98418.1 - 3e-84 282.0 5.1 3.6e-84 281.7 3.5 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EMC98418.1 - 0.00021 20.7 0.1 0.00025 20.6 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase tRNA-synt_2 PF00152.15 EMC98420.1 - 3.7e-72 242.9 0.0 5.3e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMC98420.1 - 3.7e-08 33.0 0.0 6.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMC98420.1 - 0.021 14.0 0.1 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Rtf2 PF04641.7 EMC98420.1 - 0.066 12.4 1.7 0.11 11.7 1.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger adh_short_C2 PF13561.1 EMC98421.1 - 2.7e-28 99.3 0.0 3.2e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC98421.1 - 3.9e-24 85.4 0.1 1.9e-23 83.2 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC98421.1 - 7e-06 25.8 0.1 1.6e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF1445 PF07286.7 EMC98421.1 - 0.021 14.4 0.0 1 8.9 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1445) DUF1776 PF08643.5 EMC98421.1 - 0.025 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 EMC98421.1 - 0.039 13.6 0.0 0.09 12.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SCO1-SenC PF02630.9 EMC98423.1 - 8.1e-60 201.3 0.0 1.1e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EMC98423.1 - 2.9e-07 30.2 0.0 4.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EMC98423.1 - 2.8e-05 24.1 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EMC98423.1 - 0.019 14.5 0.0 0.17 11.4 0.0 2.0 1 1 0 1 1 1 0 Redoxin FBPase PF00316.15 EMC98424.1 - 1.8e-105 352.4 0.0 2.2e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase SET PF00856.23 EMC98425.1 - 6.6e-12 46.0 0.0 5.9e-11 42.9 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 EMC98425.1 - 5.6e-08 32.3 2.0 5.6e-08 32.3 1.4 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMC98425.1 - 0.00014 21.3 6.6 0.022 14.3 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC98425.1 - 0.0018 18.0 8.6 0.4 10.7 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Thioredoxin PF00085.15 EMC98426.1 - 3.8e-25 87.5 0.0 5e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMC98426.1 - 3.3e-06 27.1 0.1 0.00065 19.7 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EMC98426.1 - 0.00071 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC98426.1 - 0.0012 19.0 0.1 0.0049 17.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EMC98426.1 - 0.0083 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EMC98426.1 - 0.031 13.8 0.1 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 EMC98426.1 - 0.04 13.6 0.1 0.15 11.7 0.1 1.8 1 1 1 2 2 2 0 AhpC/TSA family HET PF06985.6 EMC98427.1 - 2.8e-34 118.2 0.7 4.8e-34 117.4 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.16 EMC98428.1 - 2.9e-63 213.3 0.0 3.2e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 EMC98429.1 - 6.5e-27 93.4 1.1 9.7e-27 92.8 0.4 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC98429.1 - 1.3e-26 92.6 0.0 1.9e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC98429.1 - 0.00025 21.9 0.0 0.00044 21.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EMC98429.1 - 0.0022 18.2 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EMC98429.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EMC98429.1 - 0.048 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_3 PF13738.1 EMC98429.1 - 0.08 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EMC98429.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EMC98429.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 EMC98431.1 - 7.4e-22 78.3 0.0 9.4e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC98431.1 - 6.2e-14 51.9 0.0 8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC98431.1 - 1.8e-09 37.2 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EMC98431.1 - 6.6e-09 35.6 0.0 8.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMC98431.1 - 5.3e-07 30.0 0.2 2.5e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 Thioesterase domain zf-C2HC PF01530.13 EMC98431.1 - 0.0054 16.4 0.2 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C2HC type Abhydrolase_8 PF06259.7 EMC98431.1 - 0.12 11.9 0.1 1.3 8.4 0.1 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase PBP PF01161.15 EMC98435.1 - 1e-10 41.6 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Lactamase_B_2 PF12706.2 EMC98436.1 - 7.6e-32 110.4 0.1 1.2e-31 109.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC98436.1 - 9.9e-07 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 EMC98438.1 - 7.4e-18 64.3 0.1 1.5e-17 63.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC98438.1 - 6.4e-06 25.9 11.4 1e-05 25.3 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EMC98439.1 - 2.7e-65 214.0 14.8 8.2e-09 35.0 0.0 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat Urm1 PF09138.6 EMC98440.1 - 1.2e-35 121.4 0.0 1.4e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EMC98440.1 - 0.00013 22.2 0.0 0.00016 22.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family Fasciclin PF02469.17 EMC98441.1 - 1.7e-46 157.3 2.7 1.4e-26 93.0 0.0 2.5 2 1 0 2 2 2 2 Fasciclin domain Ras PF00071.17 EMC98443.1 - 5.8e-56 188.3 0.0 7.2e-56 188.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC98443.1 - 2.2e-18 66.8 0.0 3.1e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC98443.1 - 9.2e-12 44.5 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC98443.1 - 3.4e-07 30.2 0.0 4.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC98443.1 - 2e-06 27.1 0.0 2.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC98443.1 - 2.6e-06 26.9 0.0 6e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EMC98443.1 - 0.00076 19.0 0.2 0.026 14.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMC98443.1 - 0.00096 19.3 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMC98443.1 - 0.0012 18.0 0.1 0.0022 17.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EMC98443.1 - 0.0022 17.4 0.0 0.04 13.3 0.0 2.1 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EMC98443.1 - 0.0039 16.9 0.0 0.013 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EMC98443.1 - 0.0052 16.3 0.2 0.0092 15.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EMC98443.1 - 0.0077 15.9 0.1 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 EMC98443.1 - 0.0088 15.5 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 EMC98443.1 - 0.0093 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EMC98443.1 - 0.012 15.0 0.1 0.097 12.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EMC98443.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 EMC98443.1 - 0.018 14.0 0.1 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Septin MobB PF03205.9 EMC98443.1 - 0.025 14.2 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EMC98443.1 - 0.031 13.9 0.0 0.058 13.0 0.0 1.5 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 EMC98443.1 - 0.09 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EMC98443.1 - 0.15 10.8 0.2 0.43 9.3 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain JAB PF01398.16 EMC98444.1 - 1.9e-27 95.2 0.3 5.7e-27 93.7 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMC98444.1 - 4.3e-09 35.8 0.1 3.5e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EMC98444.1 - 0.019 14.4 0.1 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Fmp27 PF10344.4 EMC98445.1 - 3.1e-180 600.9 0.0 4.2e-180 600.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EMC98445.1 - 5.4e-162 539.7 0.6 1.3e-161 538.5 0.4 1.7 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EMC98445.1 - 6e-146 486.6 4.7 6e-146 486.6 3.3 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EMC98445.1 - 2.2e-54 183.6 0.2 6.2e-54 182.1 0.0 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EMC98445.1 - 3.6e-50 169.7 0.3 9.5e-50 168.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EMC98445.1 - 2.6e-32 111.3 0.2 2.1e-31 108.3 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Gp-FAR-1 PF05823.7 EMC98445.1 - 0.019 14.8 1.0 0.056 13.4 0.7 1.7 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) IF3_C PF00707.17 EMC98446.1 - 5e-09 35.7 0.0 8.5e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EMC98446.1 - 1.7e-05 24.2 0.1 0.00026 20.4 0.1 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor APC_basic PF05956.6 EMC98446.1 - 0.03 13.4 0.5 0.03 13.4 0.3 1.6 2 0 0 2 2 2 0 APC basic domain IF3_N PF05198.11 EMC98446.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain tRNA-synt_1c PF00749.16 EMC98447.1 - 4.1e-88 295.0 0.0 5.9e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1d PF00750.14 EMC98447.1 - 0.026 13.3 0.0 5.4 5.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (R) DnaJ PF00226.26 EMC98448.1 - 4.5e-22 77.5 2.2 7.3e-22 76.8 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMC98448.1 - 5.2e-21 74.3 0.0 4.4e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMC98448.1 - 8.3e-14 51.3 16.4 1.6e-13 50.5 11.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 EMC98448.1 - 0.14 12.5 5.1 0.3 11.4 3.6 1.6 1 0 0 1 1 1 0 Cytochrome c3 HypA PF01155.14 EMC98448.1 - 0.32 10.6 7.8 1.6 8.4 0.6 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 EMC98448.1 - 1.8 8.6 12.3 2.3 8.3 1.5 2.2 1 1 1 2 2 2 0 Stc1 domain zf-MYND PF01753.13 EMC98449.1 - 6e-08 32.4 18.8 1.7e-07 30.9 13.0 1.8 1 0 0 1 1 1 1 MYND finger Zip PF02535.17 EMC98449.1 - 2.9 6.8 9.9 3.1 6.7 1.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Ribosomal_L4 PF00573.17 EMC98452.1 - 1.2e-43 148.7 0.0 1.5e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 EMC98453.1 - 1.7e-08 34.4 0.0 3.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4061 PF13270.1 EMC98453.1 - 0.18 11.8 2.3 0.33 11.0 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) EXOSC1 PF10447.4 EMC98454.1 - 5.2e-25 87.2 0.0 7e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EMC98454.1 - 1.1e-07 31.0 0.0 1.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CorA PF01544.13 EMC98455.1 - 1.1e-24 87.0 8.4 1.2e-18 67.2 0.3 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein ATG16 PF08614.6 EMC98456.1 - 2e-44 151.7 16.8 2.3e-44 151.5 11.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Cast PF10174.4 EMC98456.1 - 0.00045 18.4 14.3 0.00055 18.1 9.9 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone YlqD PF11068.3 EMC98456.1 - 0.0014 18.6 10.6 0.0023 17.9 7.3 1.3 1 0 0 1 1 1 1 YlqD protein ADIP PF11559.3 EMC98456.1 - 0.0026 17.6 14.0 0.0042 16.9 9.7 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding GAS PF13851.1 EMC98456.1 - 0.0064 15.7 14.8 0.0071 15.5 9.5 1.6 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF2968 PF11180.3 EMC98456.1 - 0.0071 15.7 10.2 0.0071 15.7 7.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2968) DUF4201 PF13870.1 EMC98456.1 - 0.012 15.1 11.0 0.02 14.3 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF812 PF05667.6 EMC98456.1 - 0.016 13.7 12.2 0.017 13.6 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TMF_DNA_bd PF12329.3 EMC98456.1 - 0.017 14.9 6.5 0.017 14.9 4.5 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Filament PF00038.16 EMC98456.1 - 0.044 13.2 15.8 0.53 9.6 0.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein Mei5 PF10376.4 EMC98456.1 - 0.047 13.2 9.6 0.07 12.6 6.6 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein APG6 PF04111.7 EMC98456.1 - 0.12 11.3 12.6 0.16 10.9 8.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 EMC98456.1 - 0.13 11.8 8.0 0.21 11.1 5.5 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 EMC98456.1 - 0.15 12.2 3.9 0.56 10.3 2.1 2.3 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EMC98456.1 - 0.2 11.1 15.6 0.051 13.0 3.1 3.1 1 1 3 4 4 4 0 Septum formation initiator IncA PF04156.9 EMC98456.1 - 0.2 11.2 18.1 0.32 10.5 12.4 1.4 1 1 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 EMC98456.1 - 0.28 10.2 4.5 0.35 10.0 3.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EMC98456.1 - 0.46 9.0 12.1 0.23 10.0 6.6 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.10 EMC98456.1 - 0.61 9.2 13.0 1 8.4 9.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.1 EMC98456.1 - 0.65 9.9 14.3 0.66 9.9 2.3 2.3 1 1 1 2 2 2 0 FlxA-like protein FliD_N PF02465.13 EMC98456.1 - 1.1 9.6 10.0 1.4 9.3 4.8 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Snapin_Pallidin PF14712.1 EMC98456.1 - 1.1 9.5 11.6 0.37 11.1 2.6 2.7 1 1 1 2 2 2 0 Snapin/Pallidin Mnd1 PF03962.10 EMC98456.1 - 1.2 8.7 12.4 2 8.0 8.6 1.4 1 0 0 1 1 1 0 Mnd1 family TPR_MLP1_2 PF07926.7 EMC98456.1 - 1.3 8.8 16.2 80 2.9 11.0 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nsp1_C PF05064.8 EMC98456.1 - 1.3 8.6 10.0 0.71 9.5 1.6 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region V_ATPase_I PF01496.14 EMC98456.1 - 1.9 6.2 7.1 2.3 5.9 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 EMC98456.1 - 3.5 7.6 17.8 2.4 8.0 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ERM PF00769.14 EMC98456.1 - 4 6.9 24.6 3.8 6.9 2.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Prefoldin_2 PF01920.15 EMC98456.1 - 4.6 7.0 14.6 0.34 10.6 0.3 3.1 1 1 1 3 3 3 0 Prefoldin subunit Sec2p PF06428.6 EMC98456.1 - 5.4 6.9 15.2 6.1 6.7 0.8 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p zf-C4H2 PF10146.4 EMC98456.1 - 7.5 6.4 15.6 0.27 11.2 6.0 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein Atg14 PF10186.4 EMC98456.1 - 8 5.3 15.1 10 4.9 10.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EMC98456.1 - 8.1 6.9 16.6 2.3 8.6 1.0 3.0 1 1 2 3 3 3 0 SlyX Cortex-I_coil PF09304.5 EMC98456.1 - 9.4 6.3 17.8 2.8 8.0 1.0 2.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil Glyco_hydro_76 PF03663.9 EMC98457.1 - 3.7e-27 95.6 7.7 1.9e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Sugar_tr PF00083.19 EMC98459.1 - 1.9e-105 353.1 25.3 2.2e-105 352.8 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC98459.1 - 9.5e-32 110.0 44.6 1.9e-28 99.2 17.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC98459.1 - 2.7e-06 26.0 10.8 0.00021 19.8 1.6 3.9 4 0 0 4 4 4 2 MFS/sugar transport protein DUF791 PF05631.9 EMC98459.1 - 0.00052 18.8 0.6 0.00052 18.8 0.4 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF791) TRI12 PF06609.8 EMC98459.1 - 0.00054 18.2 1.0 0.0011 17.2 0.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 EMC98459.1 - 0.8 9.8 4.3 0.25 11.4 0.4 2.0 2 0 0 2 2 2 0 Phage holin family 2 ATP13 PF12921.2 EMC98460.1 - 1e-27 95.9 0.0 1.9e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.1 EMC98460.1 - 0.0035 17.5 0.6 95 3.6 0.0 5.4 6 0 0 6 6 6 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 EMC98460.1 - 0.1 12.5 0.1 7.7 6.5 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family LSM PF01423.17 EMC98461.1 - 2e-18 65.6 0.1 2.5e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Zn_clus PF00172.13 EMC98462.1 - 0.0032 17.3 13.0 0.0059 16.4 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EMC98462.1 - 0.0086 15.2 1.9 0.016 14.4 0.3 2.3 1 1 0 1 1 1 1 Histone chaperone domain CHZ Cyclin_N PF00134.18 EMC98463.1 - 4e-43 146.0 0.0 7.6e-43 145.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC98463.1 - 2.7e-31 107.9 0.1 6.8e-31 106.6 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain adh_short PF00106.20 EMC98464.1 - 2.6e-27 95.7 0.2 3.5e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC98464.1 - 3.6e-26 92.3 0.0 4.3e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC98464.1 - 1.3e-13 50.9 0.2 1.9e-13 50.4 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC98464.1 - 4.9e-05 22.8 0.2 0.0011 18.4 0.2 2.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EMC98464.1 - 0.017 14.9 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PFU PF09070.6 EMC98464.1 - 0.1 12.5 0.3 0.23 11.5 0.2 1.5 1 1 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Spb1_C PF07780.7 EMC98465.1 - 7.3e-63 211.9 13.7 7.3e-63 211.9 9.5 3.5 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 EMC98465.1 - 4.6e-53 179.9 0.0 1.1e-52 178.6 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EMC98465.1 - 6.3e-53 178.5 6.4 6.3e-53 178.5 4.5 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3381) AAA PF00004.24 EMC98466.1 - 9.1e-09 35.6 1.0 5.7e-08 33.0 0.7 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC98466.1 - 0.00035 20.6 0.4 0.004 17.3 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC98466.1 - 0.002 18.1 0.0 0.0096 15.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 EMC98466.1 - 0.004 15.9 0.0 0.0062 15.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EMC98466.1 - 0.0086 16.8 0.0 0.025 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EMC98466.1 - 0.011 14.4 0.0 1.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EMC98466.1 - 0.046 13.4 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EMC98466.1 - 0.069 13.4 0.0 0.38 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EMC98466.1 - 0.1 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Glyco_hydro_92 PF07971.7 EMC98467.1 - 1.4e-153 512.1 8.1 1.8e-153 511.8 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Dynamin_N PF00350.18 EMC98468.1 - 5.7e-45 153.1 0.0 1.1e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EMC98468.1 - 7.1e-10 38.1 0.2 3.3e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EMC98468.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC98468.1 - 0.0045 17.4 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Zeta_toxin PF06414.7 EMC98468.1 - 0.092 11.8 0.6 4.1 6.4 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 EMC98468.1 - 0.15 12.0 0.1 0.15 12.0 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain NMT1 PF09084.6 EMC98469.1 - 2.3e-05 24.1 0.0 0.00025 20.7 0.0 2.2 2 1 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EMC98469.1 - 0.00037 19.8 0.0 0.00098 18.4 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 EMC98469.1 - 0.061 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.11 EMC98470.1 - 6.2e-36 123.8 33.2 6.2e-36 123.8 23.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98470.1 - 8.8e-13 47.6 12.0 8.8e-13 47.6 8.3 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter Cornichon PF03311.9 EMC98470.1 - 0.011 15.8 0.2 1.8 8.7 0.0 2.8 2 1 0 2 2 2 0 Cornichon protein SurE PF01975.12 EMC98471.1 - 1e-43 148.9 0.0 1.4e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 EMC98471.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Sugar_tr PF00083.19 EMC98473.1 - 2.4e-95 319.7 28.6 2.8e-95 319.5 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC98473.1 - 1.7e-17 63.2 30.2 1.7e-17 63.2 20.9 2.0 1 1 2 3 3 3 1 Major Facilitator Superfamily Lig_chan PF00060.21 EMC98473.1 - 1.5 8.5 5.1 2.9 7.5 0.0 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel Cullin PF00888.17 EMC98474.1 - 1.7e-120 403.3 0.0 2.3e-120 402.9 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMC98474.1 - 1.1e-21 76.3 0.1 2.9e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Peripla_BP_4 PF13407.1 EMC98474.1 - 0.015 14.6 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein domain ApbA_C PF08546.6 EMC98474.1 - 0.063 13.2 0.0 0.77 9.7 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal CRCB PF02537.10 EMC98475.1 - 1.6e-27 95.7 22.6 5.2e-19 68.2 4.4 3.4 3 1 0 3 3 3 2 CrcB-like protein DUF2189 PF09955.4 EMC98475.1 - 0.067 13.1 5.0 0.34 10.8 2.9 2.7 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) UPRTase PF14681.1 EMC98476.1 - 8e-69 230.9 0.0 9.1e-69 230.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EMC98476.1 - 6.5e-10 38.8 0.0 9.2e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain KdpD PF02702.12 EMC98477.1 - 0.065 12.3 0.1 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain YajC PF02699.10 EMC98477.1 - 0.14 11.8 0.3 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Abhydrolase_6 PF12697.2 EMC98478.1 - 1.6e-14 54.3 0.1 2.3e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PalH PF08733.5 EMC98479.1 - 1.5e-82 277.2 0.2 1.2e-80 271.0 0.1 2.0 1 1 0 1 1 1 1 PalH/RIM21 Snf7 PF03357.16 EMC98480.1 - 2.7e-44 150.5 15.1 3.4e-44 150.2 10.4 1.0 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.3 EMC98480.1 - 0.00049 17.5 7.4 0.00061 17.2 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4201 PF13870.1 EMC98480.1 - 0.0033 16.8 11.1 0.0053 16.2 6.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 EMC98480.1 - 0.044 14.0 6.8 2 8.7 0.5 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EMC98480.1 - 0.15 11.2 3.6 0.45 9.6 0.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PulS_OutS PF09691.5 EMC98480.1 - 0.15 12.0 2.5 0.18 11.8 1.2 1.5 1 1 0 1 1 1 0 Bacterial chaperone lipoprotein (PulS_OutS) TMF_DNA_bd PF12329.3 EMC98480.1 - 0.16 11.7 13.2 0.48 10.2 0.0 3.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Allexi_40kDa PF05549.6 EMC98480.1 - 0.31 10.2 3.1 1.4 8.1 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein CDC37_N PF03234.9 EMC98480.1 - 0.52 10.6 9.2 0.73 10.1 6.4 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding FlaC_arch PF05377.6 EMC98480.1 - 0.54 10.1 3.9 4.2 7.3 0.0 3.0 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.11 EMC98480.1 - 0.59 10.1 12.1 1.2 9.2 8.4 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein Atg14 PF10186.4 EMC98480.1 - 0.74 8.7 9.1 1 8.2 6.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EMP24_GP25L PF01105.19 EMC98480.1 - 0.8 9.4 3.7 13 5.4 0.0 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FliT PF05400.8 EMC98480.1 - 0.84 10.0 6.7 0.82 10.1 1.4 2.8 2 1 1 3 3 3 0 Flagellar protein FliT DUF848 PF05852.6 EMC98480.1 - 1.1 9.1 5.9 1.2 8.9 2.6 2.0 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) GrpE PF01025.14 EMC98480.1 - 1.3 8.4 9.8 0.58 9.6 4.0 2.1 1 1 0 2 2 2 0 GrpE DUF4140 PF13600.1 EMC98480.1 - 1.4 9.4 4.8 2.2 8.7 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) CorA PF01544.13 EMC98480.1 - 2 7.3 5.2 18 4.2 3.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DASH_Spc19 PF08287.6 EMC98480.1 - 2.2 7.8 8.1 6.9 6.2 4.9 2.0 1 1 1 2 2 2 0 Spc19 COG2 PF06148.6 EMC98480.1 - 4 7.3 7.3 18 5.2 0.5 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4337 PF14235.1 EMC98480.1 - 6.4 6.5 8.6 0.71 9.6 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF2802 PF10975.3 EMC98480.1 - 9.1 6.1 10.2 13 5.5 0.2 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF2802) SKG6 PF08693.5 EMC98481.1 - 0.077 12.3 4.4 0.15 11.4 3.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF742 PF05331.6 EMC98481.1 - 0.11 12.1 0.5 0.18 11.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) TMEM154 PF15102.1 EMC98481.1 - 0.15 11.7 0.1 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family GTP_EFTU PF00009.22 EMC98482.1 - 4.3e-21 75.1 0.0 7.5e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMC98482.1 - 8.5e-14 51.5 0.2 1.9e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMC98482.1 - 2.6e-10 40.2 1.3 6.1e-09 35.8 0.6 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EMC98482.1 - 0.0024 17.3 0.4 1.2 8.6 0.0 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EMC98482.1 - 0.0026 18.2 0.4 0.14 12.6 0.3 3.1 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EMC98482.1 - 0.0091 15.9 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EMC98482.1 - 0.045 13.4 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu domain 4 MobB PF03205.9 EMC98482.1 - 0.095 12.4 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EMC98482.1 - 0.24 11.1 1.5 0.58 9.9 0.5 2.0 2 0 0 2 2 2 0 Dynamin family Lactamase_B PF00753.22 EMC98483.1 - 9.7e-21 74.2 4.3 1.2e-15 57.6 1.0 2.4 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily BcrAD_BadFG PF01869.15 EMC98483.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family LVIVD PF08309.6 EMC98483.1 - 0.069 12.1 0.2 0.14 11.1 0.2 1.5 1 0 0 1 1 1 0 LVIVD repeat zf-C3HC4_3 PF13920.1 EMC98484.1 - 9.6e-12 44.3 7.9 1.5e-11 43.7 5.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC98484.1 - 1.4e-10 40.8 7.7 2.2e-10 40.1 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC98484.1 - 8e-10 38.5 7.5 1.2e-09 37.9 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC98484.1 - 2.7e-08 33.3 8.5 4.2e-08 32.7 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC98484.1 - 4.4e-08 32.7 9.0 6.7e-08 32.1 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC98484.1 - 6.8e-06 25.7 3.9 1.7e-05 24.4 1.1 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC98484.1 - 7.2e-05 22.5 4.8 0.00026 20.7 3.6 1.7 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING FYVE_2 PF02318.11 EMC98484.1 - 0.0051 16.6 2.6 0.0078 16.1 1.8 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_4 PF14570.1 EMC98484.1 - 0.0061 16.1 6.3 0.011 15.2 4.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EMC98484.1 - 0.01 15.9 5.1 0.03 14.4 3.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EMC98484.1 - 0.05 13.1 4.2 0.097 12.2 2.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 EMC98484.1 - 0.075 12.9 8.2 0.14 12.0 5.7 1.4 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.1 EMC98484.1 - 0.27 10.7 8.5 0.45 10.1 2.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EMC98484.1 - 0.86 9.1 5.3 1.7 8.1 3.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger UPF0547 PF10571.4 EMC98484.1 - 8.2 6.2 9.4 2.2 8.0 0.1 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 DNA_pol_A PF00476.15 EMC98485.1 - 9.3e-95 317.4 0.0 1.4e-94 316.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EMC98485.1 - 0.12 11.8 0.1 1.6 8.2 0.0 2.4 1 1 0 1 1 1 0 3'-5' exonuclease RTA1 PF04479.8 EMC98486.1 - 3.5e-43 147.6 2.5 3.5e-43 147.6 1.7 1.3 2 0 0 2 2 2 1 RTA1 like protein SnoaL_2 PF12680.2 EMC98487.1 - 0.00085 19.6 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain HTH_7 PF02796.10 EMC98487.1 - 0.093 12.6 0.2 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DnaJ PF00226.26 EMC98488.1 - 1.1e-22 79.5 2.7 1.1e-22 79.5 1.9 2.5 2 0 0 2 2 2 1 DnaJ domain TRI5 PF06330.6 EMC98488.1 - 0.032 12.8 1.4 0.046 12.3 1.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Lumazine_bd PF12870.2 EMC98488.1 - 1.5 8.8 9.2 0.43 10.6 2.8 2.5 2 1 1 3 3 3 0 Lumazine-binding domain Sec1 PF00995.18 EMC98488.1 - 1.5 7.3 6.5 2.8 6.4 4.5 1.5 1 1 0 1 1 1 0 Sec1 family AAA_23 PF13476.1 EMC98488.1 - 1.7 8.9 7.7 2.5 8.4 5.3 1.3 1 0 0 1 1 1 0 AAA domain Malate_DH PF12434.3 EMC98488.1 - 5.4 6.8 8.6 0.14 11.8 0.4 2.7 3 0 0 3 3 3 0 Malate dehydrogenase enzyme dCMP_cyt_deam_1 PF00383.17 EMC98489.1 - 5.5e-10 38.8 0.3 1.1e-09 37.8 0.2 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EMC98489.1 - 0.02 14.5 1.4 0.032 13.8 0.9 1.5 1 1 0 1 1 1 0 APOBEC-like N-terminal domain DUF515 PF04415.7 EMC98492.1 - 6 5.0 7.3 7.4 4.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ADH_zinc_N_2 PF13602.1 EMC98493.1 - 6e-25 88.5 0.0 1.1e-24 87.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMC98493.1 - 3.2e-16 59.0 0.1 3.5e-15 55.6 0.0 2.8 2 2 2 4 4 4 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC98493.1 - 0.002 17.8 0.2 0.16 11.7 0.0 3.0 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Stn1 PF10451.4 EMC98495.1 - 1.1e-09 37.5 0.8 2.1e-08 33.3 0.6 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EMC98495.1 - 0.0057 16.4 0.6 0.034 14.0 0.4 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain CcmD PF04995.9 EMC98496.1 - 5.2 6.8 7.4 0.68 9.7 0.1 2.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Ank_2 PF12796.2 EMC98497.1 - 1.3e-09 38.2 0.0 2.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC98497.1 - 5.4e-09 36.3 0.0 2.4e-05 24.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC98497.1 - 1.5e-07 30.8 0.0 2.4e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EMC98497.1 - 2.7e-05 24.2 0.1 0.00061 19.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC98497.1 - 0.0025 17.8 0.0 0.018 15.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Methyltransf_23 PF13489.1 EMC98498.1 - 4e-22 78.6 0.0 5.6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC98498.1 - 8.2e-18 64.6 0.0 1.3e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC98498.1 - 3.1e-14 53.2 0.0 5.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC98498.1 - 5.2e-14 52.0 0.0 6.5e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC98498.1 - 7.7e-14 52.2 0.0 1.2e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC98498.1 - 9.6e-10 38.7 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC98498.1 - 1.4e-07 31.5 0.0 6.3e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC98498.1 - 2.9e-05 23.3 0.0 3.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EMC98498.1 - 0.00048 19.3 0.0 0.00067 18.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMC98498.1 - 0.00063 19.1 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EMC98498.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 EMC98498.1 - 0.007 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.15 EMC98498.1 - 0.0077 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Peroxidase_2 PF01328.12 EMC98499.1 - 2.9e-59 200.3 0.1 3.6e-59 199.9 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 FGGY_C PF02782.11 EMC98500.1 - 9.5e-74 247.2 1.1 1.8e-73 246.3 0.8 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMC98500.1 - 6.7e-59 199.1 0.0 9e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ABC2_membrane_3 PF12698.2 EMC98502.1 - 0.8 8.6 3.6 1.3 8.0 2.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Sod_Fe_C PF02777.13 EMC98503.1 - 5.2e-38 129.1 0.1 8.8e-38 128.3 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMC98503.1 - 4.2e-31 107.0 0.4 6.9e-31 106.3 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain UCR_hinge PF02320.11 EMC98504.1 - 8.7e-25 86.4 9.3 1.3e-24 85.8 6.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein F-protein PF00469.15 EMC98504.1 - 0.047 13.0 2.1 0.042 13.2 0.6 1.5 1 1 0 1 1 1 0 Negative factor, (F-Protein) or Nef UPF0203 PF05254.7 EMC98504.1 - 0.073 12.9 5.0 0.12 12.2 3.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) HET PF06985.6 EMC98505.1 - 3.6e-29 101.7 0.0 6.1e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Drf_GBD PF06371.8 EMC98506.1 - 6.6e-16 58.2 0.0 4.8e-14 52.1 0.0 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EMC98506.1 - 0.19 11.0 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Diaphanous FH3 Domain adh_short PF00106.20 EMC98507.1 - 1.9e-22 79.9 0.0 2.6e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC98507.1 - 2.5e-07 30.7 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC98507.1 - 0.00041 20.0 0.1 0.00067 19.3 0.0 1.5 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EMC98507.1 - 0.002 17.6 0.0 0.0072 15.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 EMC98507.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EMC98507.1 - 0.031 14.0 0.2 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UDPG_MGDP_dh_N PF03721.9 EMC98507.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.1 EMC98507.1 - 0.092 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Adeno_VII PF03228.9 EMC98507.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenoviral core protein VII RhoGAP PF00620.22 EMC98508.1 - 2.6e-22 79.0 0.0 3.4e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain TetR_C PF02909.12 EMC98509.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 1 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain DUF1254 PF06863.7 EMC98510.1 - 0.0078 16.0 2.8 0.014 15.1 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) Granulin PF00396.13 EMC98510.1 - 4.8 7.3 17.0 1e+02 3.1 5.1 3.3 1 1 1 2 2 2 0 Granulin Methyltransf_16 PF10294.4 EMC98511.1 - 4.6e-18 65.2 0.0 2.7e-16 59.5 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMC98511.1 - 0.0043 16.7 0.0 0.0056 16.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC98511.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Acetyltransf_8 PF13523.1 EMC98513.1 - 1.5e-44 151.5 0.0 2.4e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aminotran_1_2 PF00155.16 EMC98514.1 - 1.8e-35 122.5 0.0 2.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Nuc_sug_transp PF04142.10 EMC98515.1 - 1.3e-79 266.7 12.1 1.3e-79 266.7 8.4 1.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 EMC98515.1 - 2.5e-07 29.9 19.1 2.8e-06 26.4 12.8 2.1 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.15 EMC98515.1 - 1.3e-06 28.4 5.0 1.3e-06 28.4 3.5 3.7 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EMC98515.1 - 1.5e-05 25.1 24.2 3.9e-05 23.8 2.5 2.6 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EMC98515.1 - 0.0018 17.9 25.1 0.0033 17.0 1.5 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family Tombus_P33 PF08500.5 EMC98516.1 - 0.089 12.5 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 Tombusvirus p33 Sec63 PF02889.11 EMC98517.1 - 2.9e-50 171.2 0.0 4.1e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EMC98517.1 - 1.8e-25 89.3 0.0 4.2e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC98517.1 - 6.1e-09 35.6 0.0 1.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC98517.1 - 8.6e-08 32.2 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 EMC98517.1 - 0.00053 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 EMC98517.1 - 0.0082 16.2 0.3 0.065 13.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EMC98517.1 - 0.051 12.8 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EMC98517.1 - 0.058 13.1 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EMC98517.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EMC98517.1 - 0.099 12.2 0.0 0.43 10.2 0.0 2.1 1 1 1 2 2 2 0 Helicase UQ_con PF00179.21 EMC98518.1 - 4.8e-22 77.9 0.1 1.2e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMC98518.1 - 0.047 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 RWD domain DUF2077 PF09850.4 EMC98518.1 - 0.085 12.2 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Pex14_N PF04695.8 EMC98518.1 - 1.8 8.5 7.7 2.3 8.2 4.9 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 EMC98518.1 - 4 5.5 18.1 5.1 5.2 12.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pyridox_oxidase PF01243.15 EMC98520.1 - 1.7e-12 47.1 0.0 5.4e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Zn_clus PF00172.13 EMC98521.1 - 4.7e-05 23.2 8.3 8.7e-05 22.3 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_2 PF12680.2 EMC98521.1 - 0.092 13.1 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain His_Phos_2 PF00328.17 EMC98522.1 - 3.3e-12 46.3 0.0 1.5e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PRP21_like_P PF12230.3 EMC98525.1 - 1.4e-48 165.3 14.5 2.3e-47 161.4 10.0 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EMC98525.1 - 4.1e-30 103.1 1.0 3.5e-14 52.1 0.2 2.4 2 0 0 2 2 2 2 Surp module DUF1044 PF06296.7 EMC98525.1 - 0.044 13.6 0.4 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1044) Med9 PF07544.8 EMC98525.1 - 0.15 11.8 1.6 17 5.2 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PMT PF02366.13 EMC98526.1 - 1.4e-76 257.1 16.8 1.4e-76 257.1 11.6 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMC98526.1 - 1.2e-55 188.0 0.0 1.7e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 MIR domain UCH PF00443.24 EMC98527.1 - 9.7e-48 162.5 0.0 1.5e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC98527.1 - 1.1e-16 61.1 0.0 5.7e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HNOBA PF07701.9 EMC98527.1 - 0.03 13.5 0.0 0.03 13.5 0.0 1.7 2 0 0 2 2 2 0 Heme NO binding associated Pyr_redox_3 PF13738.1 EMC98528.1 - 1.2e-25 90.7 0.0 1.8e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC98528.1 - 0.00014 21.8 0.0 0.00073 19.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC98528.1 - 0.00016 20.7 0.0 0.0016 17.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMC98528.1 - 0.017 14.8 0.1 0.31 10.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ada_Zn_binding PF02805.11 EMC98528.1 - 0.088 12.4 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 Metal binding domain of Ada Dioxygenase_C PF00775.16 EMC98531.1 - 1.3e-50 171.1 0.0 1.8e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EMC98531.1 - 1.2e-11 44.4 0.1 2.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EMC98531.1 - 0.002 18.1 0.0 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CDP-OH_P_transf PF01066.16 EMC98532.1 - 1.6e-15 57.2 1.6 1.6e-15 57.2 1.1 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase ABC2_membrane_2 PF12679.2 EMC98532.1 - 4.7 5.9 9.1 3.1 6.5 4.8 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein NIPSNAP PF07978.8 EMC98533.1 - 9.3e-39 131.5 0.7 1.3e-28 98.9 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP FHA PF00498.21 EMC98536.1 - 8.8e-16 57.7 0.0 1.8e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain PilJ PF13675.1 EMC98536.1 - 0.0056 16.9 2.9 0.0056 16.9 2.0 2.2 2 0 0 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term Sigma70_ner PF04546.8 EMC98536.1 - 0.14 11.7 11.6 0.15 11.6 7.0 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region EMP24_GP25L PF01105.19 EMC98536.1 - 2.5 7.7 6.9 0.74 9.5 0.7 2.4 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4055 PF13264.1 EMC98536.1 - 7.4 6.6 10.1 8.9 6.3 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Uds1 PF15456.1 EMC98536.1 - 9.3 6.2 14.6 1.4 8.8 7.0 2.0 2 0 0 2 2 2 0 Up-regulated During Septation Asp_Glu_race PF01177.17 EMC98538.1 - 2.4e-28 99.5 0.7 8.3e-28 97.7 0.5 1.8 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase CN_hydrolase PF00795.17 EMC98538.1 - 6.5e-26 90.8 0.0 1.9e-24 86.0 0.0 2.3 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Glyco_trans_4_4 PF13579.1 EMC98538.1 - 0.039 14.1 2.8 0.31 11.1 0.1 3.2 4 1 0 4 4 4 0 Glycosyl transferase 4-like domain Fungal_trans PF04082.13 EMC98539.1 - 6.2e-24 84.2 0.0 9.1e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC98539.1 - 1.2e-05 25.0 9.2 1.2e-05 25.0 6.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 EMC98540.1 - 3.9e-102 342.0 35.2 4.7e-102 341.8 24.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cornichon PF03311.9 EMC98540.1 - 0.0097 16.0 3.4 0.048 13.7 0.0 2.8 3 0 0 3 3 3 1 Cornichon protein S1FA PF04689.8 EMC98540.1 - 0.17 11.7 1.0 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 DNA binding protein S1FA NAD_binding_4 PF07993.7 EMC98541.1 - 6e-36 123.6 0.0 1.1e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMC98541.1 - 4.4e-31 107.7 0.0 8.7e-31 106.7 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMC98541.1 - 2.8e-09 36.7 0.0 5.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMC98541.1 - 1.6e-06 28.2 0.0 3.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PAP1 PF08601.5 EMC98543.1 - 8.8e-10 38.7 5.1 1.4e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EMC98543.1 - 1.3e-07 31.4 11.9 2.5e-07 30.5 8.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 EMC98543.1 - 0.032 13.8 2.2 0.053 13.0 1.5 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_Maf PF03131.12 EMC98543.1 - 0.048 13.9 10.7 0.075 13.3 7.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EMC98543.1 - 0.063 13.1 11.6 0.19 11.5 8.0 1.7 1 1 0 1 1 1 0 Basic region leucine zipper Dehalogenase PF13486.1 EMC98543.1 - 0.12 11.8 0.5 0.18 11.2 0.3 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Toprim_2 PF13155.1 EMC98543.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Toprim-like ADIP PF11559.3 EMC98543.1 - 0.67 9.8 9.3 1.1 9.1 6.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Methyltrn_RNA_3 PF02598.12 EMC98544.1 - 3.7e-71 239.8 0.0 4.7e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Adaptin_N PF01602.15 EMC98545.1 - 4.1e-115 385.0 1.3 5.1e-115 384.7 0.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EMC98545.1 - 9.1e-55 184.6 0.1 2.2e-54 183.3 0.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EMC98545.1 - 2.3e-15 56.6 5.0 3.6e-05 23.9 0.0 6.5 2 2 3 5 5 5 4 HEAT repeats HEAT_PBS PF03130.11 EMC98545.1 - 0.00014 21.9 0.9 12 6.6 0.0 5.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EMC98545.1 - 0.0099 16.3 8.5 0.039 14.4 0.3 3.9 3 1 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 EMC98545.1 - 0.025 14.6 12.8 0.43 10.7 0.1 6.1 7 0 0 7 7 7 0 HEAT repeat Vitellogenin_N PF01347.17 EMC98545.1 - 0.07 11.3 1.1 1.6 6.8 0.1 2.7 2 1 0 2 2 2 0 Lipoprotein amino terminal region AA_permease_2 PF13520.1 EMC98546.1 - 1.6e-39 135.7 50.5 2e-39 135.3 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC98546.1 - 2.4e-18 65.7 40.7 3.6e-18 65.1 28.2 1.3 1 0 0 1 1 1 1 Amino acid permease Cupin_2 PF07883.6 EMC98547.1 - 5.5e-07 28.9 0.0 9.5e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMC98547.1 - 0.0038 16.5 0.2 0.016 14.5 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF861) CAP59_mtransfer PF11735.3 EMC98548.1 - 2.9e-83 278.8 0.0 4.2e-83 278.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MBA1 PF07961.6 EMC98549.1 - 1.8e-11 43.3 0.0 6e-10 38.3 0.0 2.1 2 0 0 2 2 2 2 MBA1-like protein BBIP10 PF14777.1 EMC98549.1 - 0.057 12.8 2.5 0.11 11.9 0.6 2.2 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 SUI1 PF01253.17 EMC98550.1 - 4.1e-29 100.2 6.3 5.4e-29 99.8 4.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EMC98550.1 - 0.14 12.3 0.4 0.3 11.1 0.1 1.6 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Med12 PF09497.5 EMC98551.1 - 2.2e-26 91.5 0.3 6.2e-26 90.1 0.2 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DUF1138 PF06592.8 EMC98551.1 - 0.11 12.5 0.1 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) Radical_SAM PF04055.16 EMC98553.1 - 5.3e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Sec2p PF06428.6 EMC98555.1 - 1.5e-25 88.9 12.4 1.5e-25 88.9 8.6 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Lzipper-MIP1 PF14389.1 EMC98555.1 - 0.54 10.4 14.4 0.99 9.5 3.0 3.4 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF3584 PF12128.3 EMC98555.1 - 1.4 6.1 20.3 2.5 5.3 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAD_binding_7 PF03441.9 EMC98556.1 - 1e-74 251.2 1.2 1.6e-74 250.5 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMC98556.1 - 3.9e-37 127.5 0.0 7.8e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase HAD PF12710.2 EMC98557.1 - 8.6e-16 58.6 0.0 1.1e-15 58.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC98557.1 - 1.1e-09 39.0 0.1 7.8e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC98557.1 - 1.4e-09 37.9 0.1 1.4e-08 34.6 0.0 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC98557.1 - 9.8e-07 29.1 0.0 2.2e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EMC98557.1 - 0.0025 17.0 0.0 0.39 9.8 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase CIA30 PF08547.7 EMC98558.1 - 2.3e-37 128.2 0.0 2.9e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EMC98558.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Mito_carr PF00153.22 EMC98559.1 - 7.1e-71 233.9 0.5 1.4e-23 82.4 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein MRP-L27 PF09809.4 EMC98560.1 - 2.3e-19 69.0 0.1 2.9e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.8 EMC98561.1 - 1.8e-156 522.3 50.8 1.8e-156 522.3 35.2 2.0 1 1 1 2 2 2 1 Utp14 protein Plasmid_parti PF01672.11 EMC98563.1 - 0.019 15.3 1.2 0.021 15.2 0.8 1.3 1 0 0 1 1 1 0 Putative plasmid partition protein Rep_3 PF01051.16 EMC98563.1 - 0.039 13.5 1.0 0.042 13.4 0.7 1.0 1 0 0 1 1 1 0 Initiator Replication protein RVT_1 PF00078.22 EMC98563.1 - 0.044 13.1 1.3 0.073 12.4 0.5 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) LSM PF01423.17 EMC98564.1 - 3.2e-15 55.4 0.6 4.2e-15 55.0 0.4 1.1 1 0 0 1 1 1 1 LSM domain Tail_tube PF10618.4 EMC98564.1 - 0.017 14.8 0.1 0.026 14.2 0.0 1.4 1 1 0 1 1 1 0 Phage tail tube protein SM-ATX PF14438.1 EMC98564.1 - 0.042 13.7 0.1 0.068 13.1 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF1713 PF08213.6 EMC98565.1 - 2.8e-08 33.2 16.7 2.8e-08 33.2 11.6 2.0 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) AhpC-TSA_2 PF13911.1 EMC98566.1 - 2.7e-19 69.1 0.0 4.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EMC98566.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMC98566.1 - 0.01 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin tRNA-synt_2 PF00152.15 EMC98567.1 - 1.6e-67 227.6 0.0 2e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMC98567.1 - 1.7e-10 40.5 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMC98567.1 - 0.0011 18.1 0.1 0.092 11.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) IGPS PF00218.16 EMC98568.1 - 7.4e-97 323.3 0.0 3.7e-96 321.0 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EMC98568.1 - 6.5e-53 179.2 0.3 4.2e-49 166.8 0.1 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EMC98568.1 - 1.7e-48 164.6 0.0 2.9e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NanE PF04131.9 EMC98568.1 - 3.7e-05 22.7 0.9 0.0031 16.5 0.1 2.3 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase Peptidase_C26 PF07722.8 EMC98568.1 - 4.1e-05 23.1 2.3 0.00012 21.6 0.1 2.7 3 1 0 3 3 3 1 Peptidase C26 QRPTase_C PF01729.14 EMC98568.1 - 0.0026 17.3 2.5 0.099 12.1 0.2 3.2 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EMC98568.1 - 0.068 12.4 0.5 0.55 9.4 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein BRCT PF00533.21 EMC98569.1 - 9.7e-06 25.6 0.6 3.3e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMC98569.1 - 3e-05 23.7 1.4 0.00019 21.2 0.6 2.6 2 1 0 2 2 2 1 twin BRCT domain WGR PF05406.10 EMC98569.1 - 0.052 13.5 0.1 0.052 13.5 0.1 3.3 3 1 0 3 3 3 0 WGR domain DUF4551 PF15087.1 EMC98569.1 - 0.17 10.2 6.5 0.23 9.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NDUF_B7 PF05676.8 EMC98570.1 - 8e-32 108.4 2.9 9.5e-32 108.2 2.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EMC98570.1 - 0.0034 17.1 0.9 0.0055 16.4 0.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Antifungal_prot PF11402.3 EMC98570.1 - 2.8 8.2 5.7 5.8 7.1 0.4 2.2 1 1 1 2 2 2 0 Antifungal protein Ank_2 PF12796.2 EMC98571.1 - 1.1e-14 54.4 0.1 4.7e-07 30.0 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC98571.1 - 6.6e-14 50.9 0.1 1.9e-06 27.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMC98571.1 - 3.9e-10 39.9 0.1 0.00021 21.7 0.0 3.5 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC98571.1 - 1.1e-07 31.8 0.2 0.013 15.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EMC98571.1 - 4.6e-05 23.0 0.2 0.00021 20.9 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.1 EMC98571.1 - 5.7e-05 22.9 0.1 0.54 10.6 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Clr5 PF14420.1 EMC98573.1 - 2.1e-06 27.5 0.1 8.2e-06 25.6 0.1 2.1 1 0 0 1 1 1 1 Clr5 domain PqqD PF05402.7 EMC98573.1 - 0.056 13.4 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Fungal_trans PF04082.13 EMC98574.1 - 1.1e-15 57.2 0.0 1.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC98574.1 - 6.1e-10 38.8 7.6 1e-09 38.1 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_3 PF13640.1 EMC98575.1 - 1.3e-09 38.4 0.2 3.2e-09 37.1 0.1 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMC98575.1 - 0.0016 18.0 0.1 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATG2_CAD PF13329.1 EMC98576.1 - 2.4e-28 98.7 0.0 4.2e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EMC98576.1 - 6.3e-21 74.3 1.9 1.4e-20 73.2 0.1 2.6 3 0 0 3 3 3 1 ATG C terminal domain zf-MIZ PF02891.15 EMC98577.1 - 3e-08 33.0 0.2 6.6e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SH3_9 PF14604.1 EMC98578.1 - 8.6e-14 50.8 0.0 1.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC98578.1 - 1.3e-11 43.6 0.0 2.9e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EMC98578.1 - 5.3e-10 39.4 0.0 1.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 EMC98578.1 - 1.1e-08 34.8 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EMC98578.1 - 3.3e-06 26.4 0.0 7.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EMC98578.1 - 0.00012 22.2 0.1 0.00034 20.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 EMC98578.1 - 0.0093 16.1 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Fer4_13 PF13370.1 EMC98579.1 - 0.087 13.2 4.6 3.2 8.2 0.0 4.1 3 2 1 4 4 4 0 4Fe-4S single cluster domain Aldo_ket_red PF00248.16 EMC98581.1 - 1.6e-51 174.7 0.0 1.9e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sec61_beta PF03911.11 EMC98582.1 - 6e-19 67.5 0.9 1e-18 66.8 0.6 1.4 1 0 0 1 1 1 1 Sec61beta family Preseq_ALAS PF09029.5 EMC98584.1 - 0.11 12.5 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Aa_trans PF01490.13 EMC98585.1 - 7.6e-43 146.5 33.7 8.7e-43 146.3 23.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bap31 PF05529.7 EMC98585.1 - 0.14 11.6 0.2 0.35 10.2 0.2 1.7 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF754 PF05449.6 EMC98586.1 - 0.02 14.9 0.1 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF754) Anp1 PF03452.9 EMC98587.1 - 7.4e-109 363.0 0.0 9.3e-109 362.7 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EMC98587.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 zf-C2H2 PF00096.21 EMC98589.1 - 0.03 14.6 21.8 0.033 14.5 6.7 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EMC98589.1 - 9.7 6.3 17.2 23 5.1 0.1 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) HAD_2 PF13419.1 EMC98595.1 - 4.1e-15 56.4 0.0 1.2e-14 54.8 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC98595.1 - 8.7e-05 22.1 0.1 0.00044 19.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.2 EMC98595.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase DLH PF01738.13 EMC98596.1 - 1.3e-11 44.1 0.4 2.2e-11 43.4 0.3 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family GAF_2 PF13185.1 EMC98597.1 - 3.3e-10 40.6 0.0 4.2e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EMC98597.1 - 3.2e-08 33.8 0.1 3.4e-08 33.7 0.1 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EMC98597.1 - 7.6e-07 29.2 0.0 9.6e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 GAF domain Aldo_ket_red PF00248.16 EMC98598.1 - 3.9e-52 176.8 0.0 4.5e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EMC98599.1 - 4.6e-41 140.6 10.9 4.6e-41 140.6 7.6 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98599.1 - 2.7e-13 49.3 12.6 9.9e-13 47.4 8.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMC98599.1 - 4.8e-06 25.0 4.2 9e-06 24.1 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EMC98599.1 - 0.0015 16.6 0.1 0.0027 15.8 0.1 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.17 EMC98599.1 - 0.03 13.3 2.0 0.39 9.6 0.3 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3169 PF11368.3 EMC98599.1 - 0.044 12.9 0.9 0.57 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4231 PF14015.1 EMC98599.1 - 3 7.8 7.2 0.65 10.0 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) MFS_3 PF05977.8 EMC98599.1 - 4.8 5.1 13.2 0.17 10.0 4.6 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector EMP70 PF02990.11 EMC98599.1 - 8.4 4.7 6.8 1.7 7.0 0.1 2.6 3 0 0 3 3 3 0 Endomembrane protein 70 LigB PF02900.13 EMC98600.1 - 8.8e-24 83.9 0.1 1e-23 83.7 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.13 EMC98601.1 - 3.9e-09 35.7 1.0 6.8e-09 34.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EMC98601.1 - 4.7e-08 32.9 7.1 0.0002 21.5 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC98601.1 - 1.5e-07 31.3 2.5 1.5e-07 31.3 1.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC98601.1 - 2.6e-05 24.2 12.8 0.01 16.1 1.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 EMC98601.1 - 6e-05 22.8 11.3 6e-05 22.8 7.9 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 EMC98601.1 - 1.9 8.5 14.7 2 8.4 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_S15 PF02129.13 EMC98602.1 - 3.2e-38 131.7 1.1 4.6e-38 131.1 0.8 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMC98602.1 - 3.9e-37 128.2 0.1 6.5e-37 127.5 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMC98602.1 - 1.3e-05 25.1 0.6 2.4e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC98602.1 - 0.00044 20.0 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC98602.1 - 0.035 13.9 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase adh_short PF00106.20 EMC98603.1 - 2.2e-27 96.0 2.1 6.5e-27 94.4 1.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC98603.1 - 6.5e-19 68.6 0.0 7.7e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC98603.1 - 1.4e-11 44.4 0.7 2.3e-11 43.6 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC98603.1 - 0.004 16.6 0.1 0.021 14.2 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cupin_2 PF07883.6 EMC98604.1 - 1.7e-08 33.8 0.0 2.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMC98604.1 - 0.053 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EMC98604.1 - 0.058 12.8 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Cupin Histidinol_dh PF00815.15 EMC98605.1 - 3.3e-115 385.0 0.4 4.1e-115 384.7 0.3 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase FAD_binding_3 PF01494.14 EMC98606.1 - 6.7e-21 74.7 0.3 3.9e-20 72.2 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 EMC98606.1 - 3.5e-10 39.6 0.1 1e-09 38.1 0.1 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.1 EMC98606.1 - 2.8e-06 27.2 0.4 7.1e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC98606.1 - 2.5e-05 23.3 5.7 0.00052 19.0 0.7 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC98606.1 - 0.00024 21.0 0.1 0.0037 17.1 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC98606.1 - 0.00036 19.5 1.3 0.00065 18.6 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EMC98606.1 - 0.0041 16.2 0.5 0.4 9.6 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EMC98606.1 - 0.0053 15.2 1.0 0.017 13.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 EMC98606.1 - 0.025 13.2 1.4 0.16 10.5 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EMC98606.1 - 0.025 14.6 0.1 0.064 13.3 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC98606.1 - 0.055 12.5 0.1 0.093 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EMC98606.1 - 0.085 11.7 0.8 0.14 10.9 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EMC98606.1 - 0.14 11.9 0.6 0.48 10.1 0.4 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding EamA PF00892.15 EMC98607.1 - 2.6e-10 40.3 22.6 5.6e-07 29.6 0.8 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EMC98607.1 - 4.4e-06 26.8 1.1 4.4e-06 26.8 0.8 3.5 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EMC98607.1 - 0.0073 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter PgaD PF13994.1 EMC98607.1 - 0.14 11.6 0.1 0.14 11.6 0.1 3.3 2 1 1 3 3 3 0 PgaD-like protein DUF202 PF02656.10 EMC98609.1 - 5.5e-25 87.3 0.5 5.5e-25 87.3 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) 2-Hacid_dh_C PF02826.14 EMC98613.1 - 5.1e-43 146.2 0.0 8.5e-43 145.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC98613.1 - 2.8e-10 39.7 0.0 1.1e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Acetyltransf_1 PF00583.19 EMC98614.1 - 0.0025 17.7 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC98614.1 - 0.011 15.9 0.1 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ApbA_C PF08546.6 EMC98615.1 - 5.3e-30 103.9 0.0 8.4e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMC98615.1 - 1.4e-29 102.4 0.0 2.2e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Arr-ms PF12120.3 EMC98615.1 - 0.13 12.2 0.0 0.47 10.4 0.0 2.0 2 1 0 2 2 2 0 Rifampin ADP-ribosyl transferase AAL_decarboxy PF03306.8 EMC98616.1 - 1.8e-31 108.9 0.0 4e-18 65.2 0.0 2.1 1 1 1 2 2 2 2 Alpha-acetolactate decarboxylase Pkinase PF00069.20 EMC98617.1 - 2.4e-19 69.4 0.0 4.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC98617.1 - 8.3e-09 34.8 0.0 3.2e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_2 PF13923.1 EMC98618.1 - 9.1e-10 38.4 15.8 5.2e-05 23.1 2.0 2.8 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC98618.1 - 1.2e-07 31.2 18.5 1.3e-06 27.9 3.6 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC98618.1 - 4.5e-06 26.4 16.4 0.0095 15.7 3.6 3.6 3 1 1 4 4 4 2 Ring finger domain FYVE PF01363.16 EMC98618.1 - 2e-05 24.3 9.2 3.1e-05 23.7 2.1 2.5 2 0 0 2 2 2 1 FYVE zinc finger Rtf2 PF04641.7 EMC98618.1 - 2.3e-05 23.7 2.7 0.0094 15.1 1.2 2.4 2 0 0 2 2 2 2 Rtf2 RING-finger zf-RING_5 PF14634.1 EMC98618.1 - 2.4e-05 23.9 17.7 6.9e-05 22.4 4.6 2.7 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC98618.1 - 0.0066 16.0 19.4 0.05 13.2 4.2 3.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC98618.1 - 0.013 15.2 11.0 0.024 14.3 2.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Rad50_zn_hook PF04423.9 EMC98618.1 - 0.051 13.0 1.0 2 7.9 0.1 3.1 2 0 0 2 2 2 0 Rad50 zinc hook motif FYDLN_acid PF09538.5 EMC98618.1 - 0.092 13.3 0.2 0.092 13.3 0.1 3.0 2 1 0 2 2 1 0 Protein of unknown function (FYDLN_acid) Prok-RING_1 PF14446.1 EMC98618.1 - 0.19 11.4 14.3 1.4 8.7 1.0 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 EMC98618.1 - 0.81 9.6 15.7 0.79 9.6 4.0 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING IBR PF01485.16 EMC98618.1 - 3.3 7.6 13.3 4.7 7.1 0.4 3.3 2 1 1 3 3 3 0 IBR domain Acyltransferase PF01553.16 EMC98619.1 - 8.8e-14 51.0 0.0 2.2e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase UDG PF03167.14 EMC98621.1 - 1.9e-19 69.6 0.7 3.3e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily ICMT PF04140.9 EMC98622.1 - 3.1e-27 94.6 0.1 6.4e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EMC98622.1 - 6.7e-13 48.6 0.5 6.7e-13 48.6 0.3 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EMC98622.1 - 1.3e-06 27.8 0.4 2.3e-06 27.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EMC98622.1 - 0.00068 18.2 0.9 0.0012 17.5 0.6 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PH_10 PF15411.1 EMC98625.1 - 3.2e-26 91.7 0.1 6.1e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EMC98625.1 - 3.2e-12 46.4 0.1 1.2e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EMC98625.1 - 2e-08 33.9 5.2 3.8e-08 33.0 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 EMC98625.1 - 4.8e-08 32.9 0.0 9.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 EMC98625.1 - 0.00021 20.9 4.7 0.00036 20.2 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC98625.1 - 0.00032 20.2 1.6 0.00059 19.4 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC98625.1 - 0.00039 20.3 4.3 0.00074 19.4 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC98625.1 - 0.0011 19.0 0.9 0.0024 17.9 0.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC98625.1 - 0.0055 16.3 5.2 0.01 15.4 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 EMC98625.1 - 0.011 15.9 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 PH domain DUF1147 PF06615.6 EMC98625.1 - 0.13 12.0 0.2 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 EMC98625.1 - 0.2 11.6 4.2 0.37 10.8 2.9 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EMC98625.1 - 1.5 8.4 3.0 2.6 7.6 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HYPF PF07503.7 EMC98627.1 - 0.012 14.9 0.2 0.012 14.9 0.1 2.2 2 0 0 2 2 2 0 HypF finger zf-ISL3 PF14690.1 EMC98627.1 - 0.059 13.4 3.5 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 EMC98627.1 - 0.72 9.7 5.4 3.6 7.4 3.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EMC98627.1 - 1 9.1 4.3 2.2 8.1 3.0 1.6 1 1 0 1 1 1 0 zinc-ribbons zf-ribbon_3 PF13248.1 EMC98627.1 - 3 7.1 6.2 31 3.9 4.3 2.5 1 1 0 1 1 1 0 zinc-ribbon domain HEAT PF02985.17 EMC98628.1 - 0.029 14.4 0.1 0.47 10.6 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat SCA7 PF08313.7 EMC98629.1 - 2.2e-33 113.6 2.2 2.2e-33 113.6 1.5 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.6 EMC98629.1 - 0.0011 18.2 0.7 0.002 17.3 0.5 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Neur_chan_memb PF02932.11 EMC98629.1 - 2 8.2 4.2 2.9 7.6 2.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2201_N PF13203.1 EMC98629.1 - 4.5 6.3 9.0 8.6 5.4 6.2 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain TAF4 PF05236.9 EMC98629.1 - 8.1 5.6 11.6 13 4.9 8.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family MAPEG PF01124.13 EMC98631.1 - 3.9e-22 78.2 1.6 4.9e-22 77.9 1.1 1.1 1 0 0 1 1 1 1 MAPEG family Lectin_leg-like PF03388.8 EMC98632.1 - 3.5e-71 238.9 0.1 4.4e-71 238.6 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EMC98632.1 - 0.00018 20.9 0.0 0.0012 18.2 0.0 2.0 1 1 0 1 1 1 1 Legume lectin domain ThiF PF00899.16 EMC98633.1 - 2e-33 115.1 0.0 3.4e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EMC98633.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EMC98635.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ecl1 PF12855.2 EMC98637.1 - 3.2e-13 48.7 0.3 5.3e-13 48.0 0.2 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EMC98637.1 - 0.00067 19.4 0.6 0.0011 18.7 0.4 1.3 1 0 0 1 1 1 1 MYND finger DUF581 PF04570.9 EMC98637.1 - 0.013 14.8 1.2 0.035 13.3 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF581) DUF329 PF03884.9 EMC98637.1 - 0.014 14.9 0.7 0.03 13.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) DUF2256 PF10013.4 EMC98637.1 - 2.7 7.8 5.0 0.84 9.4 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) PSK_trans_fac PF07704.6 EMC98639.1 - 1.3 9.7 5.3 1.9 9.2 2.6 2.3 2 1 0 2 2 2 0 Rv0623-like transcription factor ADH_N PF08240.7 EMC98640.1 - 3e-27 94.5 1.2 7.3e-27 93.2 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC98640.1 - 2.6e-09 36.7 0.0 4.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EMC98640.1 - 0.0019 17.7 2.7 0.0019 17.7 1.9 2.8 4 0 0 4 4 4 1 Alcohol dehydrogenase GroES-associated ABC_membrane_2 PF06472.10 EMC98642.1 - 1.4e-92 309.7 0.1 2.3e-92 309.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMC98642.1 - 7.2e-17 61.9 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC98642.1 - 0.017 15.0 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC98642.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMC98642.1 - 0.089 12.7 0.2 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain GWT1 PF06423.7 EMC98643.1 - 8.9e-36 122.9 0.0 2.2e-35 121.6 0.0 1.7 1 1 0 1 1 1 1 GWT1 Exc PF07825.6 EMC98644.1 - 0.0048 16.6 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Excisionase-like protein SET PF00856.23 EMC98646.1 - 1.9e-11 44.5 0.0 6.4e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF2404 PF10296.4 EMC98648.1 - 0.00092 19.2 0.0 0.09 12.9 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) zf-FPG_IleRS PF06827.9 EMC98650.1 - 0.037 13.6 1.1 0.056 13.0 0.8 1.4 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-RING_3 PF14369.1 EMC98650.1 - 0.066 13.2 1.1 0.18 11.8 0.7 1.8 1 1 0 1 1 1 0 zinc-finger UL73_N PF12522.3 EMC98651.1 - 4.3 6.9 9.3 13 5.4 6.4 1.8 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Catalase PF00199.14 EMC98652.1 - 5.2e-163 542.1 3.0 7e-163 541.7 2.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMC98652.1 - 3.7e-21 74.7 0.0 1.5e-20 72.7 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EMC98652.1 - 7.1e-08 32.0 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EMC98652.1 - 0.051 12.8 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase PDZ_2 PF13180.1 EMC98653.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EMC98653.1 - 1.1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 EMC98653.1 - 2.3e-05 24.4 0.0 3.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 EMC98654.1 - 9e-50 168.2 0.0 1.2e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC98654.1 - 1.6e-15 57.6 0.0 3.5e-15 56.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC98654.1 - 3.5e-11 42.6 0.0 4.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC98654.1 - 5.1e-05 22.5 0.0 6.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EMC98654.1 - 0.00047 20.2 0.1 0.0036 17.4 0.1 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EMC98654.1 - 0.013 14.1 1.7 0.41 9.2 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EMC98654.1 - 0.033 13.4 0.1 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EMC98654.1 - 0.085 13.0 0.2 0.25 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EMC98654.1 - 0.088 12.4 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SRPRB PF09439.5 EMC98654.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC98654.1 - 0.11 12.4 0.2 0.27 11.1 0.1 1.7 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EMC98654.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain ubiquitin PF00240.18 EMC98655.1 - 9e-22 76.2 0.4 2.3e-21 74.9 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EMC98655.1 - 3.7e-12 45.7 0.0 6.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC98655.1 - 0.15 12.2 0.0 0.73 10.1 0.0 2.1 2 1 0 2 2 2 0 Ubiquitin-like domain Aldedh PF00171.17 EMC98656.1 - 1.9e-142 474.8 0.0 2.3e-142 474.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC98656.1 - 0.0066 15.2 0.0 0.047 12.4 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA reductase (LuxC) MukE PF04288.8 EMC98656.1 - 0.091 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 MukE-like family PQQ PF01011.16 EMC98656.1 - 0.13 11.8 0.0 0.41 10.2 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat TCTP PF00838.12 EMC98657.1 - 0.026 14.4 0.0 0.049 13.6 0.0 1.5 2 0 0 2 2 2 0 Translationally controlled tumour protein Glyco_hydro_70 PF02324.11 EMC98657.1 - 0.13 10.0 0.0 0.17 9.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 SSF PF00474.12 EMC98658.1 - 3.4e-17 62.1 28.3 5.5e-17 61.5 19.6 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family ADH_N PF08240.7 EMC98659.1 - 1.2e-34 118.3 1.0 2.9e-34 117.1 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC98659.1 - 1.2e-24 86.3 0.7 1.9e-24 85.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC98659.1 - 0.00055 20.8 0.0 0.0011 19.8 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMC98659.1 - 0.00061 19.4 0.4 0.00097 18.7 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MTS PF05175.9 EMC98659.1 - 0.0055 16.1 0.1 0.0092 15.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UDPG_MGDP_dh_N PF03721.9 EMC98659.1 - 0.015 14.6 0.1 0.032 13.6 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Met_10 PF02475.11 EMC98659.1 - 0.017 14.7 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.2 EMC98659.1 - 0.021 15.4 0.1 0.046 14.3 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain HI0933_like PF03486.9 EMC98659.1 - 0.04 12.3 0.2 0.059 11.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.16 EMC98659.1 - 0.076 12.8 0.2 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 EMC98659.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.1 EMC98659.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain DUF1996 PF09362.5 EMC98661.1 - 6.8e-81 271.3 1.4 9.9e-81 270.8 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EMC98661.1 - 1.1e-19 70.1 11.6 3.7e-19 68.4 8.0 2.0 1 0 0 1 1 1 1 WSC domain DUF2207 PF09972.4 EMC98664.1 - 0.066 11.8 0.0 0.082 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.3 EMC98664.1 - 0.47 10.0 5.6 0.27 10.8 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Cmc1 PF08583.5 EMC98665.1 - 6.2e-12 45.1 18.2 2.4e-11 43.2 12.6 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DDHD PF02862.12 EMC98665.1 - 0.064 13.0 0.4 0.075 12.8 0.3 1.0 1 0 0 1 1 1 0 DDHD domain CHCH PF06747.8 EMC98665.1 - 0.42 10.5 8.9 2.8 7.9 6.1 2.1 1 1 0 1 1 1 0 CHCH domain DUF3323 PF11796.3 EMC98665.1 - 0.56 9.4 3.7 0.73 9.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DUF1903 PF08991.5 EMC98665.1 - 6.4 7.0 8.5 12 6.1 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) WD40 PF00400.27 EMC98666.1 - 2.2e-55 182.6 13.6 2.4e-08 33.5 0.0 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Gmad1 PF10647.4 EMC98666.1 - 5.1e-06 26.0 0.7 3.8e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 EMC98666.1 - 0.0029 16.4 1.4 0.38 9.4 0.2 2.9 1 1 1 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EMC98666.1 - 0.0089 14.3 0.0 0.013 13.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain BBS2_Mid PF14783.1 EMC98666.1 - 0.031 14.0 0.0 22 4.9 0.0 3.4 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region TRAPP PF04051.11 EMC98667.1 - 8e-31 106.6 0.0 9.5e-31 106.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GFA PF04828.9 EMC98670.1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme FRG1 PF06229.7 EMC98673.1 - 2.3e-49 167.4 3.3 3.2e-49 166.9 2.3 1.2 1 0 0 1 1 1 1 FRG1-like family tRNA-synt_1c_C PF03950.13 EMC98673.1 - 0.056 13.1 0.5 0.099 12.3 0.3 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Fascin PF06268.8 EMC98673.1 - 0.061 13.4 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Fascin domain Pyr_redox_2 PF07992.9 EMC98674.1 - 1.9e-25 89.9 0.7 3.1e-25 89.2 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EMC98674.1 - 2.4e-14 52.6 0.1 7.4e-14 51.0 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 EMC98674.1 - 4e-14 52.7 1.9 1.4e-13 51.0 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC98674.1 - 2.8e-08 34.0 0.0 1e-05 25.6 0.0 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EMC98674.1 - 3.4e-06 26.7 0.0 1.4e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Trp_halogenase PF04820.9 EMC98674.1 - 5.5e-05 21.9 0.3 0.00012 20.8 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Reductase_C PF14759.1 EMC98674.1 - 0.0029 17.8 0.0 0.0066 16.7 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 EMC98674.1 - 0.015 14.2 0.0 1.3 7.8 0.0 2.2 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 EMC98674.1 - 0.043 13.4 0.4 0.08 12.5 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMC98674.1 - 0.063 12.6 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sel1 PF08238.7 EMC98675.1 - 2.9e-47 158.0 38.9 2.2e-06 28.1 0.3 13.0 13 0 0 13 13 12 10 Sel1 repeat TPR_11 PF13414.1 EMC98675.1 - 7.6e-05 22.2 14.0 0.11 12.1 0.1 5.7 4 1 2 6 6 6 3 TPR repeat Nro1 PF12753.2 EMC98675.1 - 0.024 13.6 2.0 2.4 7.0 1.5 2.5 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 TPR_12 PF13424.1 EMC98675.1 - 0.025 14.5 0.2 0.025 14.5 0.1 5.7 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC98675.1 - 0.031 14.0 11.2 0.38 10.6 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC98675.1 - 0.033 13.8 0.0 0.033 13.8 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMC98675.1 - 0.042 14.5 0.1 0.042 14.5 0.0 8.3 7 2 2 9 9 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC98675.1 - 0.38 10.7 0.1 0.38 10.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC98675.1 - 0.63 10.1 0.0 0.63 10.1 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC98675.1 - 0.74 10.4 20.3 7.8 7.2 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC98675.1 - 1 9.7 6.0 3.3 8.1 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC98675.1 - 3 7.8 0.0 3 7.8 0.0 6.7 7 1 1 8 8 8 0 Tetratricopeptide repeat F-box-like PF12937.2 EMC98676.1 - 8.1e-08 31.8 0.2 1.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC98676.1 - 4e-05 23.1 0.2 7.3e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain NUP50 PF08911.6 EMC98677.1 - 5.9e-05 23.3 1.5 5.9e-05 23.3 1.0 6.9 6 1 1 7 7 7 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 EMC98677.1 - 7.1e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain U79_P34 PF03064.11 EMC98677.1 - 0.03 13.8 1.3 0.069 12.6 0.9 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SCP2 PF02036.12 EMC98678.1 - 4.3e-21 75.1 1.1 5.1e-21 74.8 0.8 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EMC98678.1 - 4.2e-05 23.5 0.2 4.7e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Serum_albumin PF00273.15 EMC98679.1 - 0.041 13.3 0.2 0.043 13.2 0.1 1.0 1 0 0 1 1 1 0 Serum albumin family PSP94 PF05825.6 EMC98679.1 - 0.073 13.3 0.3 0.087 13.1 0.2 1.1 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) PEP_mutase PF13714.1 EMC98680.1 - 5.4e-47 160.0 0.2 6.2e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMC98680.1 - 1.9e-21 75.8 0.3 2.5e-21 75.4 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family MFS_1 PF07690.11 EMC98681.1 - 1.2e-36 126.2 34.3 1.2e-36 126.2 23.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98681.1 - 6.4e-09 34.9 20.5 6.4e-09 34.9 14.2 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMC98681.1 - 2.7e-07 29.1 2.8 5.5e-07 28.1 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.6 EMC98681.1 - 2.8 7.1 8.3 0.25 10.6 1.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) ABM PF03992.11 EMC98682.1 - 8.8e-05 22.4 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF482 PF04339.7 EMC98682.1 - 0.0079 15.1 0.1 0.0083 15.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF482 DUF641 PF04859.7 EMC98684.1 - 0.094 12.4 0.2 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Cortex-I_coil PF09304.5 EMC98684.1 - 0.49 10.4 3.1 12 6.0 0.8 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil CLTH PF10607.4 EMC98685.1 - 1.5e-29 102.5 0.0 2.7e-28 98.5 0.0 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EMC98685.1 - 2.4e-16 59.1 0.8 5.8e-16 57.9 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMC98685.1 - 0.00022 20.9 0.6 0.00043 20.0 0.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC98685.1 - 0.0043 17.0 0.9 0.008 16.1 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EMC98685.1 - 0.007 15.6 0.1 0.017 14.3 0.1 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 EMC98685.1 - 0.0073 16.0 0.4 0.014 15.0 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TMEM247 PF15444.1 EMC98685.1 - 0.065 13.0 1.0 7.6 6.2 0.1 2.3 1 1 1 2 2 2 0 Transmembrane protein 247 Plasmid_RAQPRD PF09686.5 EMC98685.1 - 0.067 13.2 0.2 0.35 10.9 0.1 2.1 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) zf-C3HC4_3 PF13920.1 EMC98685.1 - 0.069 12.8 0.4 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC98685.1 - 0.075 12.7 0.7 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps16_C PF04840.7 EMC98685.1 - 0.19 10.6 1.9 4.5 6.1 0.1 2.3 2 1 0 2 2 2 0 Vps16, C-terminal region zf-Nse PF11789.3 EMC98685.1 - 0.3 10.6 2.1 0.66 9.5 1.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Syntaxin_2 PF14523.1 EMC98685.1 - 0.51 10.4 3.2 5.5 7.0 0.9 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Laminin_II PF06009.7 EMC98685.1 - 0.9 9.2 3.1 5.1 6.8 0.4 2.8 2 1 1 3 3 3 0 Laminin Domain II ADIP PF11559.3 EMC98686.1 - 9.3e-34 116.5 15.3 2.5e-33 115.1 10.6 1.7 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding L27 PF02828.11 EMC98686.1 - 0.015 14.9 0.8 2.5 7.8 0.0 3.3 2 2 2 4 4 4 0 L27 domain BMFP PF04380.8 EMC98686.1 - 0.019 15.0 0.1 0.019 15.0 0.0 3.4 3 1 2 5 5 5 0 Membrane fusogenic activity Cytochrom_B562 PF07361.6 EMC98686.1 - 0.046 14.1 5.0 0.13 12.7 2.9 2.1 2 0 0 2 2 2 0 Cytochrome b562 IncA PF04156.9 EMC98686.1 - 0.084 12.4 18.7 0.37 10.3 7.6 3.2 2 1 0 2 2 2 0 IncA protein DUF4167 PF13763.1 EMC98686.1 - 0.1 12.6 1.8 0.2 11.7 0.8 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4167) APG6 PF04111.7 EMC98686.1 - 0.1 11.6 14.0 0.028 13.4 7.4 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 Syntaxin PF00804.20 EMC98686.1 - 0.12 12.5 11.1 0.058 13.5 3.4 3.1 2 2 1 3 3 3 0 Syntaxin Baculo_PEP_C PF04513.7 EMC98686.1 - 0.12 12.2 5.7 2.7 7.8 0.6 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.1 EMC98686.1 - 0.17 11.8 16.9 0.05 13.5 8.0 2.4 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 EMC98686.1 - 0.21 11.3 19.2 2.9 7.6 0.1 3.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 EMC98686.1 - 0.29 11.0 15.7 5.3 7.0 0.1 3.7 2 1 1 3 3 3 0 bZIP transcription factor LXG PF04740.7 EMC98686.1 - 0.34 10.6 6.9 11 5.7 0.6 3.4 3 1 1 4 4 4 0 LXG domain of WXG superfamily Pex19 PF04614.7 EMC98686.1 - 0.49 9.9 7.8 0.16 11.6 3.0 1.7 2 0 0 2 2 2 0 Pex19 protein family GldM_N PF12081.3 EMC98686.1 - 0.53 9.7 5.0 0.6 9.6 2.4 1.9 2 0 0 2 2 2 0 GldM N-terminal domain Filament PF00038.16 EMC98686.1 - 0.55 9.6 14.8 0.3 10.5 6.9 2.6 2 1 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 EMC98686.1 - 0.81 8.2 13.4 0.84 8.2 8.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EMC98686.1 - 1.1 7.0 7.3 0.26 9.0 2.9 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Acetyltransf_11 PF13720.1 EMC98686.1 - 1.6 9.0 4.5 2.9 8.1 0.2 2.8 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FlxA PF14282.1 EMC98686.1 - 2.5 8.0 9.3 0.35 10.8 3.3 2.0 2 0 0 2 2 2 0 FlxA-like protein Spc24 PF08286.6 EMC98686.1 - 3.2 7.4 13.4 1.8 8.2 0.8 3.3 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 MSG PF02349.10 EMC98686.1 - 3.6 7.6 9.9 11 6.0 1.0 2.3 1 1 1 2 2 2 0 Major surface glycoprotein Bacillus_HBL PF05791.6 EMC98686.1 - 4.1 6.7 8.5 0.54 9.6 0.9 2.8 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Bap31 PF05529.7 EMC98686.1 - 9.3 5.6 15.6 1 8.8 1.3 2.8 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like Scytalone_dh PF02982.9 EMC98687.1 - 1.2e-75 252.5 2.7 1.3e-75 252.3 1.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EMC98687.1 - 1.5e-08 34.5 1.3 2.1e-08 34.1 0.9 1.1 1 0 0 1 1 1 1 SnoaL-like domain PKI PF02827.11 EMC98689.1 - 0.043 13.9 4.1 0.93 9.6 1.1 2.5 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor DUF4611 PF15387.1 EMC98689.1 - 0.65 10.1 5.3 1.3 9.2 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.1 EMC98689.1 - 0.69 9.5 4.2 1.3 8.6 2.9 1.5 1 0 0 1 1 1 0 FAM176 family EBV-NA3 PF05009.7 EMC98689.1 - 0.93 8.6 4.8 1.5 7.9 3.3 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Pox_RNA_Pol_19 PF05320.7 EMC98689.1 - 1.9 8.2 5.3 1.7 8.3 2.6 1.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SOG2 PF10428.4 EMC98689.1 - 4.4 5.8 9.1 5.5 5.5 6.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Phosphodiest PF01663.17 EMC98690.1 - 0.01 15.1 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2265 PF10023.4 EMC98694.1 - 0.2 10.7 5.3 0.26 10.3 3.6 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Motilin_ghrelin PF04644.7 EMC98694.1 - 0.74 9.6 5.5 0.36 10.6 1.5 2.2 1 1 1 2 2 2 0 Motilin/ghrelin eIF-3_zeta PF05091.7 EMC98694.1 - 0.8 8.2 10.1 1 7.9 7.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ADH_zinc_N PF00107.21 EMC98696.1 - 3.9e-22 78.1 0.0 6.4e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC98696.1 - 1.2e-06 29.4 0.0 2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Maf PF02545.9 EMC98697.1 - 5.1e-49 166.0 0.0 5.9e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Fungal_trans PF04082.13 EMC98698.1 - 1e-25 90.1 0.1 1.6e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC98698.1 - 3.6e-08 33.1 13.4 6e-08 32.4 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 EMC98699.1 - 4e-21 75.0 0.0 7.3e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EMC98699.1 - 7.2e-11 42.4 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EMC98699.1 - 2.5e-08 33.9 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain RGS PF00615.14 EMC98701.1 - 6e-11 42.4 0.0 1.9e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Glyco_hydro_12 PF01670.11 EMC98704.1 - 1.4e-51 174.3 3.2 2.3e-51 173.6 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF2205 PF10224.4 EMC98706.1 - 5.1e-30 102.8 0.2 7.2e-30 102.3 0.1 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EMC98706.1 - 0.071 13.4 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Bul1_N PF04425.7 EMC98707.1 - 1.8e-07 30.0 0.6 9.3e-06 24.4 0.6 2.6 2 1 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 EMC98707.1 - 1.3e-05 24.5 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 EMC98707.1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF3068 PF11271.3 EMC98707.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) DUF3357 PF11837.3 EMC98708.1 - 0.34 10.7 2.2 0.68 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4234 PF14018.1 EMC98708.1 - 0.92 9.2 12.6 3.9 7.2 4.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) NPR2 PF06218.6 EMC98710.1 - 5.4e-103 344.9 0.0 9.5e-103 344.1 0.0 1.3 1 0 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EMC98710.1 - 0.0065 15.0 0.1 0.075 11.5 0.1 2.4 2 1 1 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 DDE_Tnp_1_2 PF13586.1 EMC98710.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain VIT1 PF01988.14 EMC98711.1 - 2.7e-43 147.9 0.9 3e-43 147.7 0.6 1.0 1 0 0 1 1 1 1 VIT family DUF1799 PF08809.6 EMC98712.1 - 0.04 13.7 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) Abhydrolase_5 PF12695.2 EMC98715.1 - 4.9e-06 26.3 0.1 7.3e-06 25.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC98715.1 - 1.2e-05 25.3 2.6 1.9e-05 24.6 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EMC98715.1 - 2.5e-05 23.6 0.1 5.7e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 EMC98715.1 - 0.02 14.3 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EMC98715.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMC98715.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1100 PF06500.6 EMC98715.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) VWA_3 PF13768.1 EMC98716.1 - 1.2e-34 119.2 0.1 1.1e-30 106.3 0.0 3.1 3 0 0 3 3 3 2 von Willebrand factor type A domain VIT PF08487.5 EMC98716.1 - 9.2e-14 51.1 0.0 2.2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EMC98716.1 - 7.6e-12 45.6 0.0 1.7e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMC98716.1 - 1.2e-10 41.4 0.1 2e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EMC98716.1 - 4.4e-07 29.2 0.0 1.3e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EMC98716.1 - 0.00058 19.0 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 EMC98716.1 - 0.0054 16.5 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Rad4 PF03835.10 EMC98716.1 - 0.026 13.9 0.4 0.051 12.9 0.2 1.4 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain HLH PF00010.21 EMC98717.1 - 5.1e-06 26.0 0.0 6.7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Membr_traf_MHD PF10540.4 EMC98718.1 - 1.5e-23 83.1 0.2 3.9e-23 81.7 0.1 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EMC98718.1 - 6.8e-15 54.6 0.0 1.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.11 EMC98719.1 - 4.3e-29 101.3 67.8 3.5e-23 81.8 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98719.1 - 0.00021 19.9 6.6 0.00021 19.9 4.5 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter fn3 PF00041.16 EMC98720.1 - 0.00019 21.4 0.0 0.00065 19.7 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain LNS2 PF08235.8 EMC98721.1 - 6.9e-67 223.9 0.0 1.1e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EMC98721.1 - 6.6e-40 135.2 0.2 3.8e-39 132.7 0.0 2.2 2 0 0 2 2 2 1 lipin, N-terminal conserved region Chromo PF00385.19 EMC98722.1 - 2.3e-15 55.9 4.9 1e-06 28.3 0.0 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain SLX9 PF15341.1 EMC98722.1 - 0.25 11.8 13.1 44 4.5 7.0 3.7 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 DUF3445 PF11927.3 EMC98723.1 - 5.5e-69 232.3 0.0 7e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Pyr_redox_3 PF13738.1 EMC98724.1 - 2.3e-28 99.6 0.0 6.2e-28 98.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC98724.1 - 2.4e-15 55.7 0.0 9.5e-15 53.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMC98724.1 - 1.9e-09 36.9 0.1 5.8e-06 25.4 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMC98724.1 - 1.5e-08 34.8 0.0 3.1e-07 30.4 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC98724.1 - 7.2e-08 32.3 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC98724.1 - 4.2e-05 22.6 0.0 7.7e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC98724.1 - 5.7e-05 23.4 0.2 0.06 13.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC98724.1 - 6.7e-05 22.7 0.0 0.0026 17.5 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EMC98724.1 - 0.00076 19.5 0.0 0.5 10.4 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EMC98724.1 - 0.0018 17.4 0.1 0.005 15.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EMC98724.1 - 0.0062 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMC98724.1 - 0.013 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EMC98724.1 - 0.34 9.3 1.6 0.3 9.4 0.2 1.5 2 0 0 2 2 2 0 HI0933-like protein DLH PF01738.13 EMC98725.1 - 0.029 13.6 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family PRP38 PF03371.10 EMC98726.1 - 9e-62 207.7 0.0 1.1e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 PRP38 family PilX_N PF14341.1 EMC98727.1 - 0.069 12.8 0.5 4 7.1 0.0 2.4 2 0 0 2 2 2 0 PilX N-terminal Acyl-CoA_dh_1 PF00441.19 EMC98728.1 - 4.4e-41 140.4 5.0 6.9e-41 139.8 3.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC98728.1 - 5.7e-30 104.2 0.4 2.4e-29 102.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMC98728.1 - 1.1e-18 66.5 0.0 2.6e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC98728.1 - 1.1e-15 58.0 2.0 1.1e-15 58.0 1.4 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain FliH PF02108.11 EMC98730.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Flagellar assembly protein FliH IncA PF04156.9 EMC98730.1 - 0.061 12.9 1.9 0.085 12.4 1.3 1.2 1 0 0 1 1 1 0 IncA protein DUF4254 PF14063.1 EMC98730.1 - 0.63 9.6 5.2 0.47 10.0 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) Pkinase PF00069.20 EMC98731.1 - 1.9e-59 200.9 0.0 3e-59 200.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC98731.1 - 1.7e-36 125.6 0.0 1.7e-32 112.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMC98731.1 - 2.8e-06 26.5 0.2 0.006 15.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 EMC98731.1 - 0.00022 20.6 0.1 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMC98731.1 - 0.00046 19.9 0.1 0.0013 18.4 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC98731.1 - 0.0072 15.4 0.1 0.018 14.0 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC98731.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL E1-E2_ATPase PF00122.15 EMC98732.1 - 4.7e-54 182.8 1.6 1.1e-53 181.6 1.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMC98732.1 - 6.1e-48 164.0 4.2 8.3e-48 163.6 0.4 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMC98732.1 - 5.3e-47 157.8 0.2 3.5e-12 46.2 0.2 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EMC98732.1 - 1.3e-13 51.5 0.0 4.1e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 EMC98732.1 - 0.0012 18.7 1.4 1.1 9.1 0.0 4.2 5 0 0 5 5 5 1 B12 binding domain Hydrolase_3 PF08282.7 EMC98732.1 - 0.0033 17.0 0.5 0.0093 15.5 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Redoxin PF08534.5 EMC98733.1 - 2.3e-22 79.1 0.0 2.8e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMC98733.1 - 1.2e-12 47.5 0.0 8.3e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family K1 PF02960.9 EMC98734.1 - 0.1 12.6 0.2 0.12 12.4 0.1 1.3 1 1 0 1 1 1 0 K1 glycoprotein Histidinol_dh PF00815.15 EMC98735.1 - 3.7e-177 589.0 4.7 5.4e-177 588.5 3.2 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EMC98735.1 - 2.8e-26 90.9 0.2 5.7e-26 89.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase Pkinase PF00069.20 EMC98735.1 - 1.8e-17 63.3 0.0 3.8e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PRA-PH PF01503.12 EMC98735.1 - 5e-10 39.5 0.1 1.4e-09 38.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Pkinase_Tyr PF07714.12 EMC98735.1 - 3.8e-08 32.7 0.0 7.6e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MazG PF03819.12 EMC98735.1 - 0.0072 16.2 0.3 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Cellulase PF00150.13 EMC98736.1 - 5.3e-44 150.5 0.6 6.9e-44 150.1 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TFIID-31kDa PF02291.10 EMC98737.1 - 1.2e-34 118.8 0.0 9.9e-34 115.9 0.0 2.0 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Utp11 PF03998.8 EMC98738.1 - 4.2e-51 174.1 18.6 4.8e-51 173.9 12.9 1.0 1 0 0 1 1 1 1 Utp11 protein RRN3 PF05327.6 EMC98738.1 - 3.7 5.5 7.0 4.9 5.1 4.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3332 PF11810.3 EMC98738.1 - 6.9 6.2 8.4 11 5.6 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) adh_short PF00106.20 EMC98739.1 - 1.2e-24 87.1 0.0 1.5e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC98739.1 - 6.3e-13 48.7 0.0 1.2e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC98739.1 - 6.2e-06 26.1 0.0 9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC98739.1 - 0.0018 17.7 0.0 0.013 14.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC98739.1 - 0.034 14.1 0.3 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Saccharop_dh PF03435.13 EMC98739.1 - 0.052 12.5 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase Form-deh_trans PF09163.6 EMC98740.1 - 0.045 13.2 0.5 0.1 12.1 0.3 1.5 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Lactamase_B_2 PF12706.2 EMC98741.1 - 1.8e-12 47.1 0.1 5e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EMC98741.1 - 7.2e-06 26.0 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 EMC98741.1 - 0.00027 20.6 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EMC98741.1 - 0.031 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase ApbA_C PF08546.6 EMC98742.1 - 4.5e-29 100.9 0.0 6.5e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMC98742.1 - 1.1e-26 93.1 0.0 1.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EMC98742.1 - 0.017 14.0 1.1 0.032 13.1 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EMC98742.1 - 0.039 14.2 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sec7 PF01369.15 EMC98743.1 - 2.3e-43 148.0 0.0 3.8e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EMC98743.1 - 7.5e-08 32.5 0.1 1.8e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMC98743.1 - 4.7e-05 23.5 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 PH domain JAB PF01398.16 EMC98746.1 - 0.00037 20.2 0.0 0.00085 19.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Voltage_CLC PF00654.15 EMC98747.1 - 1.6e-93 313.5 22.7 3e-93 312.6 15.7 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel adh_short PF00106.20 EMC98748.1 - 2.6e-15 56.7 0.3 5e-15 55.8 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC98748.1 - 1.7e-07 31.2 0.0 2.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC98748.1 - 3e-05 23.7 0.0 6.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC98748.1 - 0.0014 18.1 0.1 0.0034 16.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC98748.1 - 0.0043 16.0 0.1 0.03 13.2 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein Methyltransf_26 PF13659.1 EMC98748.1 - 0.065 13.2 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CDKN3 PF05706.7 EMC98748.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) GDPD PF03009.12 EMC98749.1 - 1.2e-12 47.9 0.0 3.7e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family DUF1833 PF08875.6 EMC98749.1 - 0.0033 16.6 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1833) JmjN PF02375.12 EMC98749.1 - 0.34 10.4 1.7 0.8 9.2 1.2 1.6 1 0 0 1 1 1 0 jmjN domain Mcp5_PH PF12814.2 EMC98750.1 - 3e-42 143.4 0.6 6.8e-42 142.2 0.2 1.9 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology IncA PF04156.9 EMC98750.1 - 0.0022 17.6 3.6 0.0022 17.6 2.5 4.4 3 1 1 4 4 4 1 IncA protein TPR_MLP1_2 PF07926.7 EMC98750.1 - 2.1 8.1 38.3 0.049 13.3 11.3 4.1 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EMC98750.1 - 3.6 7.4 40.6 0.16 11.8 4.6 5.2 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EMC98750.1 - 7.7 6.3 22.7 1.3 8.7 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) zf-C3HC4_2 PF13923.1 EMC98751.1 - 9.2e-09 35.1 9.9 1.6e-08 34.4 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EMC98751.1 - 2.8e-08 33.2 2.3 5.8e-08 32.2 1.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EMC98751.1 - 6.3e-08 32.3 6.6 1e-07 31.6 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC98751.1 - 3.5e-07 29.7 6.3 6e-07 29.0 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC98751.1 - 4.1e-07 29.5 10.6 7.1e-07 28.7 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC98751.1 - 8.5e-07 28.5 9.6 1.5e-06 27.8 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC98751.1 - 3.6e-05 23.5 8.0 8e-05 22.4 5.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC98751.1 - 9.1e-05 22.0 2.9 0.00019 21.0 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EMC98751.1 - 0.0068 15.9 4.5 0.011 15.1 3.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L37e PF01907.14 EMC98751.1 - 1.8 8.3 9.5 1.1 9.0 3.6 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e Histidinol_dh PF00815.15 EMC98752.1 - 2.4e-115 385.4 0.1 3e-115 385.1 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase TRI12 PF06609.8 EMC98753.1 - 7.5e-26 90.4 22.9 1e-25 90.0 15.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMC98753.1 - 9.5e-14 50.8 60.3 2.9e-11 42.6 37.0 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EMC98754.1 - 1.9e-16 60.1 0.0 3e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EMC98754.1 - 0.0032 16.3 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.19 EMC98754.1 - 0.091 11.8 0.0 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EMC98755.1 - 1.9e-15 56.8 0.4 1.1e-14 54.2 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 EMC98755.1 - 1.3e-11 44.3 0.0 2.2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_3 PF13738.1 EMC98755.1 - 1.8e-05 24.8 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC98755.1 - 2.4e-05 24.2 2.2 9.2e-05 22.3 0.7 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC98755.1 - 3e-05 23.0 3.7 0.00021 20.3 1.0 2.3 1 1 2 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC98755.1 - 0.00047 19.1 3.4 0.00074 18.4 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC98755.1 - 0.0013 18.7 0.4 0.0058 16.5 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMC98755.1 - 0.0015 17.6 1.3 0.35 9.9 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EMC98755.1 - 0.0019 17.3 0.1 0.0037 16.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMC98755.1 - 0.012 15.1 0.2 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EMC98755.1 - 0.028 13.0 0.2 0.76 8.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EMC98755.1 - 0.03 13.1 1.6 0.05 12.4 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EMC98755.1 - 0.037 12.4 0.8 0.074 11.5 0.6 1.5 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EMC98755.1 - 0.042 12.7 0.9 0.22 10.3 0.6 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMC98755.1 - 0.054 13.9 0.4 0.19 12.1 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4503 PF14951.1 EMC98756.1 - 0.00076 17.7 0.2 0.00084 17.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) DUF3844 PF12955.2 EMC98756.1 - 0.2 11.7 1.1 0.22 11.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) zf-B_box PF00643.19 EMC98756.1 - 0.24 11.3 2.4 0.49 10.3 1.7 1.6 1 1 0 1 1 1 0 B-box zinc finger Aldedh PF00171.17 EMC98757.1 - 4.7e-07 28.4 0.4 1.7e-06 26.6 0.3 1.9 1 1 1 2 2 2 1 Aldehyde dehydrogenase family LigB PF02900.13 EMC98759.1 - 1.7e-18 66.5 0.0 2.6e-18 65.9 0.0 1.3 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MR_MLE_C PF13378.1 EMC98760.1 - 2.6e-32 111.1 0.1 5.1e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EMC98760.1 - 3.8e-25 88.1 0.0 3.6e-23 81.7 0.0 2.3 2 0 0 2 2 2 2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EMC98760.1 - 1.2e-12 48.1 0.3 3e-12 46.8 0.2 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Peptidase_S15 PF02129.13 EMC98761.1 - 2.3e-41 142.0 0.0 3.4e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMC98761.1 - 3.3e-31 108.8 0.2 5.7e-31 108.0 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMC98761.1 - 9.8e-07 28.8 0.1 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC98761.1 - 0.0017 18.0 0.0 0.0036 17.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family ApbA_C PF08546.6 EMC98762.1 - 1.8e-29 102.3 0.0 2.8e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMC98762.1 - 8.2e-28 96.7 0.0 1.5e-27 95.8 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EMC98762.1 - 0.099 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_10 PF13460.1 EMC98762.1 - 0.1 12.6 0.0 0.37 10.7 0.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding zf-H2C2_2 PF13465.1 EMC98763.1 - 1.3e-09 37.8 2.6 5e-07 29.7 1.2 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC98763.1 - 3.6e-09 36.4 8.8 0.0002 21.5 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 EMC98763.1 - 7.1e-05 22.6 13.0 0.00021 21.1 9.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EMC98763.1 - 0.00071 19.7 9.4 0.0064 16.7 0.9 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC98763.1 - 0.0023 17.7 6.2 0.37 10.7 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EMC98763.1 - 0.0037 17.4 1.6 1.4 9.2 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC98763.1 - 0.024 14.7 1.3 0.23 11.6 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.11 EMC98764.1 - 8.5e-28 97.0 38.7 3.3e-26 91.8 17.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98764.1 - 5.5e-09 35.1 3.2 5.5e-09 35.1 2.2 2.5 2 1 0 3 3 3 1 Sugar (and other) transporter DUF1751 PF08551.5 EMC98764.1 - 0.0074 16.5 0.1 0.0074 16.5 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF3278 PF11683.3 EMC98764.1 - 0.031 14.2 1.7 0.061 13.3 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) MpPF26 PF07666.6 EMC98764.1 - 0.057 13.3 3.0 0.06 13.2 0.1 2.4 2 0 0 2 2 2 0 M penetrans paralogue family 26 MRAP PF15183.1 EMC98764.1 - 0.071 12.7 0.1 0.3 10.7 0.0 2.0 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Glyoxalase PF00903.20 EMC98765.1 - 1.9e-06 27.8 2.7 3.9e-06 26.8 1.3 2.0 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMC98765.1 - 2e-06 28.3 4.7 0.00038 21.0 0.1 2.6 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMC98765.1 - 0.0018 18.2 0.1 0.0085 16.0 0.1 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADC PF06314.6 EMC98766.1 - 1.7e-11 43.9 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Peptidase_S15 PF02129.13 EMC98769.1 - 1.3e-41 142.8 0.5 1.9e-41 142.2 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMC98769.1 - 3.9e-32 111.9 0.1 5.7e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMC98769.1 - 7.9e-05 22.6 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC98769.1 - 0.0024 17.6 0.0 0.0058 16.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cupin_2 PF07883.6 EMC98770.1 - 7.7e-09 34.9 0.0 1.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EMC98770.1 - 0.0012 18.4 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Cupin p450 PF00067.17 EMC98771.1 - 2.1e-67 227.6 0.0 2.6e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EMC98772.1 - 7.7e-86 288.3 0.0 1e-85 287.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC98772.1 - 0.0019 18.0 0.1 0.0042 16.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC98772.1 - 0.072 11.9 0.1 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EMC98772.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family PUF PF00806.14 EMC98773.1 - 9.5e-29 97.2 0.0 1.4e-05 24.3 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EMC98773.1 - 4.6e-11 42.2 0.0 1.3e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC98773.1 - 2.9e-06 27.0 0.3 9.4e-06 25.3 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC98773.1 - 5.2e-05 23.1 0.1 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.4 EMC98774.1 - 1.6e-21 76.5 0.0 2.4e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EMC98774.1 - 4.7e-09 35.8 0.1 9.2e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMC98774.1 - 8.9e-08 32.7 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC98774.1 - 1.4e-07 30.8 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EMC98774.1 - 9.7e-05 22.3 0.8 0.00026 20.9 0.2 2.1 2 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EMC98774.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.15 EMC98774.1 - 0.00019 20.5 0.0 0.00043 19.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 EMC98774.1 - 0.0013 19.2 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC98774.1 - 0.0046 17.4 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 EMC98774.1 - 0.0095 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EMC98774.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 EMC98775.1 - 1.2e-34 117.9 0.0 2e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 EMC98775.1 - 0.034 13.5 0.6 0.046 13.1 0.4 1.2 1 0 0 1 1 1 0 RRXRR protein Toxin_8 PF07365.7 EMC98776.1 - 0.12 12.3 0.8 0.18 11.7 0.6 1.3 1 0 0 1 1 1 0 Alpha conotoxin precursor Bap31 PF05529.7 EMC98778.1 - 6.8e-65 218.1 1.8 7.7e-65 217.9 1.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 EMC98778.1 - 0.013 14.9 1.2 0.021 14.2 0.8 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4349 PF14257.1 EMC98778.1 - 0.021 14.0 0.7 0.042 13.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CCDC155 PF14662.1 EMC98778.1 - 0.024 14.2 0.3 0.044 13.3 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 TMF_DNA_bd PF12329.3 EMC98778.1 - 0.061 13.1 3.4 0.091 12.5 0.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 EMC98778.1 - 0.068 12.7 0.4 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 EMC98778.1 - 0.079 12.1 0.4 0.12 11.5 0.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EMC98778.1 - 0.22 11.0 6.8 2.7 7.5 0.4 3.4 2 1 1 3 3 3 0 Septum formation initiator Cep57_CLD_2 PF14197.1 EMC98778.1 - 0.32 10.9 2.9 4.9 7.1 0.3 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Dus PF01207.12 EMC98779.1 - 1.9e-34 118.8 0.0 2.6e-24 85.6 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EMC98779.1 - 0.013 15.1 3.9 0.49 10.1 0.1 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Toxin_20 PF08089.6 EMC98779.1 - 1.7 8.6 5.1 5.8 6.8 3.5 1.9 1 1 0 1 1 1 0 Huwentoxin-II family Amidohydro_2 PF04909.9 EMC98780.1 - 1.1e-22 80.8 0.2 3.8e-22 79.1 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase adh_short_C2 PF13561.1 EMC98781.1 - 2.2e-30 106.1 0.0 2.6e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC98781.1 - 1.3e-25 90.2 1.1 1.6e-25 89.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC98781.1 - 5.8e-11 42.3 0.3 8.8e-11 41.7 0.2 1.2 1 0 0 1 1 1 1 KR domain DEAD PF00270.24 EMC98782.1 - 9.8e-27 93.5 0.0 2.1e-26 92.4 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC98782.1 - 1.1e-22 79.6 0.1 6.7e-22 77.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC98782.1 - 0.00024 20.9 0.1 0.00068 19.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UreE_N PF02814.10 EMC98782.1 - 0.2 11.1 2.9 0.54 9.8 0.0 2.9 3 0 0 3 3 3 0 UreE urease accessory protein, N-terminal domain ATP-synt_G PF04718.10 EMC98783.1 - 1.8e-22 79.9 0.6 1.8e-21 76.6 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF883 PF05957.8 EMC98783.1 - 0.0047 17.2 11.6 0.015 15.6 3.9 2.5 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 EMC98783.1 - 1.3 9.0 14.6 2.5 8.0 5.3 2.8 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Glyco_tranf_2_3 PF13641.1 EMC98785.1 - 5e-26 91.9 0.2 7.3e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMC98785.1 - 3.4e-10 39.4 0.0 2.1e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMC98785.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 bZIP_1 PF00170.16 EMC98786.1 - 0.0001 22.2 3.2 0.00022 21.1 2.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor Anthrax-tox_M PF09156.5 EMC98786.1 - 0.14 11.2 0.0 0.7 8.9 0.0 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain Cellulase PF00150.13 EMC98788.1 - 1.4e-15 57.2 4.9 5e-15 55.4 3.4 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cerato-platanin PF07249.7 EMC98789.1 - 5.8e-53 177.9 2.4 6.8e-53 177.7 1.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EMC98789.1 - 0.015 14.9 1.8 0.06 13.0 1.3 1.8 1 1 0 1 1 1 0 Barwin family Gly_kinase PF02595.10 EMC98790.1 - 0.035 12.7 0.2 0.039 12.6 0.1 1.0 1 0 0 1 1 1 0 Glycerate kinase family HAMP PF00672.20 EMC98791.1 - 7.4e-50 167.0 15.9 4.6e-09 36.3 0.0 6.9 6 0 0 6 6 6 6 HAMP domain Response_reg PF00072.19 EMC98791.1 - 1.8e-28 98.8 1.3 6.9e-27 93.6 0.4 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EMC98791.1 - 1.3e-27 95.6 2.1 8.7e-27 93.0 0.1 2.9 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMC98791.1 - 2.2e-17 62.8 0.5 2.2e-17 62.8 0.3 4.7 7 0 0 7 7 7 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EMC98791.1 - 1.9e-05 23.4 19.4 0.0023 16.4 0.1 3.4 1 1 1 3 3 3 3 AAA domain NAAA-beta PF15508.1 EMC98791.1 - 0.0047 17.2 4.9 5 7.5 0.1 5.5 5 2 1 6 6 6 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pox_A_type_inc PF04508.7 EMC98791.1 - 0.075 12.8 6.3 1.2 9.1 0.0 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF2365 PF10157.4 EMC98791.1 - 0.11 12.3 11.0 4.7 7.0 0.1 6.2 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2365) DUF2205 PF10224.4 EMC98791.1 - 0.13 11.8 5.0 4.4 6.9 0.0 4.1 4 0 0 4 4 4 0 Predicted coiled-coil protein (DUF2205) DUF948 PF06103.6 EMC98791.1 - 0.63 9.9 30.2 6.4 6.7 0.2 8.4 6 3 2 9 9 8 0 Bacterial protein of unknown function (DUF948) CCDC-167 PF15188.1 EMC98791.1 - 1.7 8.6 12.7 7.7 6.5 0.0 6.1 7 1 1 8 8 7 0 Coiled-coil domain-containing protein 167 Glyco_hydro_31 PF01055.21 EMC98792.1 - 4.2e-162 539.9 6.1 5.7e-162 539.5 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AA_permease_2 PF13520.1 EMC98793.1 - 2.2e-28 98.9 35.1 2.6e-28 98.7 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC98793.1 - 2.4e-23 82.2 29.5 2.9e-23 81.9 20.5 1.0 1 0 0 1 1 1 1 Amino acid permease LigD_N PF13298.1 EMC98795.1 - 1.6e-21 76.4 0.2 4.8e-21 74.8 0.2 1.8 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) zf-Tim10_DDP PF02953.10 EMC98796.1 - 2e-24 84.6 1.4 2.4e-24 84.4 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EMC98796.1 - 0.079 12.4 1.3 0.11 11.9 0.9 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) FAD_binding_8 PF08022.7 EMC98797.1 - 1e-23 83.2 0.0 2.1e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMC98797.1 - 3.7e-21 75.6 0.0 6.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMC98797.1 - 6e-18 65.1 9.1 6e-18 65.1 6.3 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMC98797.1 - 1.9e-05 24.6 0.0 6.8e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMC98797.1 - 0.11 13.0 0.0 2.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1479 PF07350.7 EMC98799.1 - 1.1e-163 544.5 0.0 1.3e-163 544.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EMC98799.1 - 0.076 13.0 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_1 PF00232.13 EMC98800.1 - 6e-161 535.6 0.1 7.4e-161 535.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF904 PF06005.7 EMC98801.1 - 0.018 15.3 1.0 0.03 14.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EMC98801.1 - 0.019 14.9 9.7 0.25 11.3 6.8 2.1 1 1 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.8 EMC98801.1 - 0.13 12.6 0.1 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4094 PF13334.1 EMC98801.1 - 0.19 12.1 2.3 0.46 10.9 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) IncA PF04156.9 EMC98801.1 - 0.69 9.4 3.6 1.1 8.8 2.5 1.2 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EMC98801.1 - 5.6 6.8 12.5 15 5.4 0.5 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DIOX_N PF14226.1 EMC98802.1 - 1.2e-31 109.6 0.0 9.2e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMC98802.1 - 6.8e-13 48.7 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Noc2 PF03715.8 EMC98803.1 - 4.6e-111 370.4 0.0 7.1e-111 369.8 0.0 1.3 1 0 0 1 1 1 1 Noc2p family Methyltransf_16 PF10294.4 EMC98804.1 - 2.7e-18 66.0 0.0 1.2e-14 54.1 0.0 2.8 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_23 PF13489.1 EMC98804.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC98804.1 - 0.0015 18.5 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC98804.1 - 0.0065 17.0 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC98804.1 - 0.077 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EMC98804.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PPV_E2_C PF00511.12 EMC98807.1 - 0.037 13.9 0.1 0.037 13.9 0.1 1.1 1 0 0 1 1 1 0 E2 (early) protein, C terminal SAG PF04092.8 EMC98807.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 SRS domain PAF-AH_p_II PF03403.8 EMC98808.1 - 1e-43 149.1 0.0 1.9e-42 144.8 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMC98808.1 - 6e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC98808.1 - 6.4e-06 26.2 0.2 1.3e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMC98808.1 - 1.1e-05 24.4 0.0 8.5e-05 21.5 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMC98808.1 - 2.6e-05 23.1 0.0 4.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 EMC98808.1 - 0.00017 21.4 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EMC98808.1 - 0.055 12.7 0.0 0.18 11.0 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF3298 PF11738.3 EMC98808.1 - 0.068 13.6 0.3 0.15 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) GATA PF00320.22 EMC98810.1 - 8.3e-16 57.0 4.2 1.8e-15 55.9 2.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EMC98810.1 - 2.5e-12 46.6 0.0 5.4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EMC98810.1 - 4.5e-10 39.3 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EMC98810.1 - 6.3e-10 39.3 0.0 1.9e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EMC98810.1 - 7.6e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EMC98810.1 - 7.7e-06 25.8 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain DUF4428 PF14471.1 EMC98810.1 - 0.3 10.8 3.1 0.19 11.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) RRN7 PF11781.3 EMC98810.1 - 2.2 7.8 4.9 9.5 5.8 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 F-box-like PF12937.2 EMC98812.1 - 2.3e-06 27.2 0.0 2.3e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMC98812.1 - 0.00084 18.9 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 F-box domain HAD PF12710.2 EMC98814.1 - 3.3e-18 66.5 0.2 1e-17 64.9 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMC98814.1 - 6.7e-18 64.5 0.0 1.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMC98814.1 - 1.8e-13 51.3 1.0 2e-12 48.0 0.7 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC98814.1 - 4.4e-11 42.5 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC98814.1 - 0.0038 16.8 0.1 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC98814.1 - 0.11 12.7 0.1 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Gp_dh_N PF00044.19 EMC98814.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Zip PF02535.17 EMC98815.1 - 1.6e-31 109.5 4.9 4.2e-31 108.1 3.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Ank_5 PF13857.1 EMC98816.1 - 2.8e-08 33.7 0.8 7.2e-08 32.4 0.6 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EMC98816.1 - 6.4e-05 22.5 0.8 0.00014 21.4 0.6 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EMC98816.1 - 0.00015 22.0 0.2 0.00034 20.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC98816.1 - 0.012 16.1 0.1 0.027 15.0 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC98816.1 - 0.14 12.4 0.2 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat adh_short PF00106.20 EMC98817.1 - 2.5e-20 73.0 0.1 4.7e-19 68.9 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC98817.1 - 6.8e-20 71.8 0.0 1.9e-19 70.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC98817.1 - 4.7e-08 32.9 0.1 1e-05 25.3 0.0 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EMC98817.1 - 0.0057 16.1 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMC98817.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HsbA PF12296.3 EMC98818.1 - 8e-14 51.5 0.6 1.1e-13 51.0 0.4 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A PBP PF01161.15 EMC98820.1 - 5.6e-13 48.9 0.1 7.6e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FTR_C PF02741.10 EMC98820.1 - 0.16 11.7 0.3 0.28 10.9 0.2 1.4 1 0 0 1 1 1 0 FTR, proximal lobe DUF3446 PF11928.3 EMC98820.1 - 9 6.5 7.2 6 7.1 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) Fungal_trans_2 PF11951.3 EMC98821.1 - 1.9e-08 33.3 0.3 2.6e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC98821.1 - 4.5e-07 29.6 10.2 9e-07 28.7 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CfAFP PF05264.6 EMC98821.1 - 0.74 9.5 5.1 0.43 10.3 1.1 2.3 2 0 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Catalase PF00199.14 EMC98822.1 - 4e-55 187.0 0.6 4.9e-55 186.7 0.4 1.1 1 0 0 1 1 1 1 Catalase Ras PF00071.17 EMC98823.1 - 2.2e-45 153.9 0.0 2.7e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC98823.1 - 1.7e-16 60.7 0.0 2.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC98823.1 - 2.4e-13 49.7 0.0 4.1e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC98823.1 - 6e-07 29.0 0.0 1.2e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC98823.1 - 1.8e-05 23.9 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC98823.1 - 0.00028 20.7 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EMC98823.1 - 0.00036 20.0 0.1 0.059 12.8 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EMC98823.1 - 0.0017 17.6 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EMC98823.1 - 0.0034 17.5 0.1 0.011 15.8 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EMC98823.1 - 0.0036 17.2 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMC98823.1 - 0.0067 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EMC98823.1 - 0.01 15.0 0.0 0.023 13.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EMC98823.1 - 0.016 14.8 0.0 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EMC98823.1 - 0.016 15.1 0.0 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 EMC98823.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EMC98823.1 - 0.044 13.7 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMC98823.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMC98823.1 - 0.093 12.4 0.1 0.23 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EMC98823.1 - 0.2 10.3 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Glyoxalase_2 PF12681.2 EMC98824.1 - 5.7e-10 39.7 0.4 2.7e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EMC98824.1 - 1e-08 35.1 3.3 5.8e-06 26.3 1.6 2.8 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SET PF00856.23 EMC98825.1 - 3.9e-08 33.7 0.0 8.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 SET domain G-alpha PF00503.15 EMC98826.1 - 1.8e-117 392.3 0.1 2.1e-117 392.0 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC98826.1 - 2.3e-15 56.3 2.4 1.7e-10 40.4 0.1 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC98826.1 - 2e-06 27.1 0.1 0.00038 19.6 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Peptidase_C70 PF12385.3 EMC98826.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 DUF2985 PF11204.3 EMC98826.1 - 0.029 14.1 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) FtsK_SpoIIIE PF01580.13 EMC98826.1 - 0.03 13.7 0.0 0.082 12.3 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EMC98826.1 - 0.038 14.4 0.0 8.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EMC98826.1 - 0.058 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EMC98826.1 - 0.07 12.5 0.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pex24p PF06398.6 EMC98827.1 - 2.1e-83 280.1 1.0 2.5e-83 279.8 0.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EMC98827.1 - 0.0026 15.7 1.6 0.29 8.9 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) Peptidase_C78 PF07910.8 EMC98829.1 - 2.5e-39 134.6 0.0 3.1e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 DUF2014 PF09427.5 EMC98830.1 - 2e-79 266.4 0.8 3.1e-79 265.8 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EMC98830.1 - 1e-14 53.9 0.4 2.1e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TMF_DNA_bd PF12329.3 EMC98830.1 - 0.2 11.5 1.7 0.33 10.7 0.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ECH PF00378.15 EMC98832.1 - 5.4e-38 130.5 0.0 6.5e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Amidohydro_2 PF04909.9 EMC98833.1 - 3.6e-42 144.8 0.0 4.3e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EMC98833.1 - 0.089 11.9 0.0 0.35 10.0 0.0 2.0 1 1 0 1 1 1 0 TatD related DNase DUF1950 PF09187.5 EMC98835.1 - 0.016 15.3 0.2 0.023 14.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function(DUF1950) DnaJ PF00226.26 EMC98836.1 - 2.2e-11 43.3 0.0 3.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Solute_trans_a PF03619.11 EMC98837.1 - 2.8e-84 282.6 15.9 3.2e-84 282.5 11.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Colicin_V PF02674.11 EMC98837.1 - 0.024 14.4 9.3 0.078 12.8 0.4 2.8 2 0 0 2 2 2 0 Colicin V production protein NfeD PF01957.13 EMC98837.1 - 0.19 11.8 11.1 0.21 11.7 2.1 3.1 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DPM3 PF08285.6 EMC98837.1 - 0.42 10.4 7.8 0.42 10.4 1.4 2.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WSC PF01822.14 EMC98838.1 - 1.9e-09 37.3 13.6 1.9e-09 37.3 9.4 2.6 2 0 0 2 2 2 1 WSC domain Macoilin PF09726.4 EMC98838.1 - 1.5 7.0 10.0 1.6 6.9 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein RAI16-like PF10257.4 EMC98839.1 - 8.6e-62 209.0 2.3 1.3e-61 208.5 1.6 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein EST1_DNA_bind PF10373.4 EMC98843.1 - 0.074 12.2 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Ubiq_cyt_C_chap PF03981.7 EMC98844.1 - 1.2e-34 119.1 1.4 1.9e-34 118.5 0.9 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone mRNA_cap_enzyme PF01331.14 EMC98845.1 - 1.3e-47 161.9 0.0 2e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EMC98845.1 - 1.4e-17 63.9 0.1 3.1e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EMC98845.1 - 0.00011 21.7 0.0 0.0017 17.7 0.0 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PaREP1 PF05942.6 EMC98845.1 - 0.12 12.2 2.4 0.26 11.1 1.6 1.5 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family HEAT_2 PF13646.1 EMC98847.1 - 3.9e-08 33.4 7.2 5.7e-05 23.3 0.1 5.5 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EMC98847.1 - 4.1e-08 32.6 5.1 0.081 13.0 0.2 6.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EMC98847.1 - 3.5e-05 24.1 9.2 0.016 15.6 0.7 5.5 5 1 1 6 6 6 2 HEAT-like repeat ketoacyl-synt PF00109.21 EMC98848.1 - 3.9e-58 196.9 7.7 2.2e-56 191.1 1.8 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMC98848.1 - 4.9e-36 123.1 3.1 1.2e-35 121.9 0.7 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMC98848.1 - 4.1e-06 25.9 0.1 2.5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC98848.1 - 5.6e-05 22.5 3.4 0.00099 18.5 0.1 3.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain NicO PF03824.11 EMC98849.1 - 1.2e-56 192.1 18.1 1.2e-56 192.1 12.5 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein zf-C2H2_4 PF13894.1 EMC98850.1 - 9.5e-10 38.1 14.5 0.0045 17.2 0.4 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC98850.1 - 0.00025 21.2 18.7 0.082 13.2 3.6 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type Defensin_2 PF01097.13 EMC98853.1 - 0.47 10.2 5.1 0.94 9.2 1.4 2.1 2 0 0 2 2 2 0 Arthropod defensin GCS PF03074.11 EMC98855.1 - 5.9e-151 502.7 0.0 1.5e-150 501.3 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.22 EMC98855.1 - 2.1e-14 52.5 5.2 4.8e-14 51.4 3.6 1.7 1 0 0 1 1 1 1 GATA zinc finger Hexapep PF00132.19 EMC98856.1 - 1.4e-10 40.1 13.2 4.1e-06 26.0 1.9 5.0 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMC98856.1 - 1.7e-08 33.8 5.1 9.8e-06 25.0 0.5 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase PI-PLC-X PF00388.14 EMC98857.1 - 2.7e-11 43.0 0.0 4.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PKD PF00801.15 EMC98857.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 PKD domain Meth_synt_2 PF01717.13 EMC98858.1 - 1.2e-14 54.0 0.0 1.7e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMC98858.1 - 0.0027 17.0 0.0 0.42 9.8 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain ADH_N PF08240.7 EMC98859.1 - 2.4e-27 94.8 3.6 6.6e-27 93.4 2.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC98859.1 - 1.1e-19 70.3 0.2 2.1e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EMC98859.1 - 0.011 14.7 0.2 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 EMC98859.1 - 0.023 15.1 0.3 0.08 13.3 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 EMC98859.1 - 0.041 13.9 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMC98859.1 - 0.044 13.1 0.1 0.074 12.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EMC98859.1 - 0.052 13.1 1.5 0.13 11.8 0.9 1.7 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMC98859.1 - 0.054 13.4 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 EMC98859.1 - 0.062 13.1 0.7 0.45 10.3 0.3 2.2 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 EMC98859.1 - 0.08 13.2 0.2 0.21 11.8 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EMC98859.1 - 0.12 11.4 0.2 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMC98859.1 - 0.23 11.0 2.3 2.8 7.5 0.9 2.2 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-synt_C PF00137.16 EMC98860.1 - 1e-31 108.6 28.2 9.7e-19 67.0 8.5 2.0 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 EMC98860.1 - 0.11 11.6 3.4 3.2 6.8 0.2 2.1 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor Flavi_NS4A PF01350.12 EMC98860.1 - 0.81 9.2 4.4 0.33 10.4 1.0 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2970 PF11174.3 EMC98860.1 - 2.7 7.6 9.8 0.4 10.2 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ribosomal_L7Ae PF01248.21 EMC98861.1 - 4e-25 87.1 0.0 4.6e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMC98861.1 - 0.0028 17.5 0.1 0.0037 17.1 0.1 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EMC98861.1 - 0.085 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Abhydrolase_3 PF07859.8 EMC98864.1 - 1.4e-57 194.6 0.0 2.3e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMC98864.1 - 5.1e-05 22.1 0.1 8.9e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EMC98864.1 - 0.062 12.5 0.0 0.91 8.6 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family RhoGEF PF00621.15 EMC98865.1 - 3.7e-16 59.5 0.0 6.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EMC98865.1 - 0.015 15.4 0.0 0.054 13.6 0.0 2.0 2 0 0 2 2 2 0 PH domain MFS_1 PF07690.11 EMC98866.1 - 8.4e-40 136.5 26.4 1e-39 136.2 18.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PrgI PF12666.2 EMC98866.1 - 0.0026 17.8 0.6 0.0026 17.8 0.4 3.5 4 0 0 4 4 4 2 PrgI family protein TPR_11 PF13414.1 EMC98867.1 - 0.0032 17.0 2.1 0.0061 16.1 0.3 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EMC98867.1 - 0.031 14.1 1.7 2.4 8.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC98867.1 - 0.034 14.0 0.6 0.54 10.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC98867.1 - 0.046 13.3 2.8 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Tim10_DDP PF02953.10 EMC98869.1 - 8.2e-22 76.2 1.2 9.9e-22 76.0 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EMC98869.1 - 0.016 15.0 0.1 0.023 14.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) NatB_MDM20 PF09797.4 EMC98869.1 - 0.044 12.4 0.2 0.047 12.4 0.1 1.0 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Endonuclease_NS PF01223.18 EMC98870.1 - 2.4e-58 197.1 0.0 3.1e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2217 PF10265.4 EMC98872.1 - 0.3 9.7 2.2 0.34 9.6 1.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Herpes_capsid PF06112.6 EMC98872.1 - 0.9 9.5 8.5 1.4 8.9 5.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribonuc_L-PSP PF01042.16 EMC98873.1 - 5.3e-31 106.8 0.1 5.8e-31 106.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4488 PF14869.1 EMC98873.1 - 0.045 13.3 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Nucleoside_tran PF01733.13 EMC98874.1 - 9.9e-34 116.8 0.2 3.6e-31 108.4 0.2 2.3 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.11 EMC98874.1 - 3.2e-05 22.8 17.0 0.0025 16.5 3.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP_assoc PF03828.14 EMC98876.1 - 9.3e-18 63.9 0.1 2.1e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMC98876.1 - 1.1e-05 25.7 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EMC98876.1 - 0.0026 16.6 0.0 0.33 9.7 0.0 2.2 2 0 0 2 2 2 2 Poly(A) polymerase central domain Isochorismatase PF00857.15 EMC98877.1 - 4.6e-32 111.3 0.0 5.8e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family SHD1 PF03983.7 EMC98878.1 - 0.037 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Isochorismatase PF00857.15 EMC98879.1 - 2.1e-24 86.4 0.0 9.1e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 Isochorismatase family Hydrolase_like PF13242.1 EMC98879.1 - 0.018 14.7 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 0 HAD-hyrolase-like Mito_carr PF00153.22 EMC98880.1 - 6.7e-71 234.0 1.9 2.9e-23 81.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHFR_1 PF00186.14 EMC98881.1 - 2.1e-29 102.2 0.0 7e-28 97.2 0.0 2.1 1 1 0 1 1 1 1 Dihydrofolate reductase Orthopox_F14 PF06076.7 EMC98881.1 - 0.12 12.4 0.0 0.97 9.5 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus F14 protein COesterase PF00135.23 EMC98882.1 - 4.1e-91 306.3 2.1 5.9e-91 305.7 1.5 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC98882.1 - 0.0001 21.9 0.3 0.00063 19.3 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lyase_1 PF00206.15 EMC98883.1 - 2e-33 115.9 0.0 4.6e-33 114.7 0.0 1.7 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 EMC98883.1 - 4.5e-11 42.6 0.0 2.3e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 Adenylosuccinate lyase C-terminus Crp PF00325.15 EMC98883.1 - 0.051 13.0 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF2439 PF10382.4 EMC98884.1 - 2.7e-24 85.1 0.2 4.7e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Autophagy_N PF03986.8 EMC98886.1 - 4.3e-39 133.5 0.0 8e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EMC98886.1 - 1.7e-20 72.9 0.7 3.4e-20 71.9 0.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EMC98886.1 - 1.5e-14 52.7 0.4 2.7e-14 51.9 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF3857 PF12969.2 EMC98886.1 - 0.059 12.9 0.4 0.11 12.0 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) SDA1 PF05285.7 EMC98886.1 - 3.2 6.9 12.1 2.4 7.3 3.5 2.1 2 0 0 2 2 2 0 SDA1 zf-C3HC4_3 PF13920.1 EMC98887.1 - 2.6e-10 39.8 10.8 2.6e-10 39.8 7.5 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC98887.1 - 0.00038 20.4 10.9 0.00038 20.4 7.6 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MRP-L46 PF11788.3 EMC98889.1 - 1.8e-30 105.8 0.1 1.4e-29 103.0 0.1 2.3 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EMC98889.1 - 0.076 12.6 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 NUDIX domain LRR_4 PF12799.2 EMC98890.1 - 7.8e-41 137.0 24.4 2e-10 40.0 1.2 7.0 2 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC98890.1 - 1.3e-24 85.6 23.1 9.5e-09 34.8 2.6 5.5 3 1 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EMC98890.1 - 9.4e-15 52.3 27.3 0.35 11.0 0.1 11.8 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_7 PF13504.1 EMC98890.1 - 6.5e-11 40.5 17.7 1.1 9.7 0.0 10.3 11 0 0 11 11 11 3 Leucine rich repeat LRR_6 PF13516.1 EMC98890.1 - 3.5e-10 38.8 17.3 0.3 11.2 0.0 9.7 5 3 5 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.1 EMC98890.1 - 2.7e-09 36.8 9.9 0.00056 19.5 0.2 3.9 1 1 3 4 4 4 2 Leucine-rich repeat Zn_clus PF00172.13 EMC98891.1 - 2e-09 37.1 10.3 4.4e-09 36.0 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC98891.1 - 3.2e-08 32.7 0.0 1.2e-07 30.8 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain SYS1 PF09801.4 EMC98891.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network NCD3G PF07562.9 EMC98892.1 - 0.047 13.4 3.3 0.11 12.2 2.3 1.6 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Toxin_1 PF00087.16 EMC98892.1 - 3.2 8.1 8.8 3.6 8.0 4.7 2.1 2 1 0 2 2 2 0 Snake toxin PPR_2 PF13041.1 EMC98893.1 - 0.0044 16.9 0.0 0.4 10.6 0.0 3.2 3 0 0 3 3 3 1 PPR repeat family DUF1160 PF06648.6 EMC98893.1 - 0.34 10.6 0.0 0.72 9.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) PPR_3 PF13812.1 EMC98893.1 - 0.4 11.0 3.7 51 4.5 0.0 5.2 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Cpn60_TCP1 PF00118.19 EMC98896.1 - 1.3e-129 433.0 5.5 2.8e-129 431.8 3.8 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myc_N PF01056.13 EMC98896.1 - 0.0077 15.4 1.2 0.013 14.7 0.9 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Oxidored_FMN PF00724.15 EMC98898.1 - 8.6e-51 172.9 0.0 1.1e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.13 EMC98898.1 - 0.0033 16.3 0.0 0.0068 15.2 0.0 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Dus PF01207.12 EMC98898.1 - 0.044 12.6 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) RRM_6 PF14259.1 EMC98899.1 - 6.6e-38 128.5 0.0 4.4e-09 36.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC98899.1 - 5.7e-37 125.1 0.0 3e-11 42.7 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC98899.1 - 5.4e-18 64.5 0.0 0.00055 19.7 0.2 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EMC98899.1 - 3e-12 45.9 8.4 1.1e-11 44.0 5.8 2.1 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 EMC98899.1 - 0.00046 20.0 0.0 0.044 13.6 0.1 2.5 2 0 0 2 2 2 1 RNA binding motif WAC_Acf1_DNA_bd PF10537.4 EMC98900.1 - 2.5e-26 91.8 1.6 5.5e-26 90.7 0.0 2.4 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EMC98900.1 - 5.7e-13 48.4 0.2 1.4e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EMC98900.1 - 3.5e-08 33.0 0.2 9.3e-08 31.7 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EMC98900.1 - 0.00035 20.3 2.2 0.001 18.8 1.5 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Alg6_Alg8 PF03155.10 EMC98901.1 - 5.2e-146 487.1 24.8 6.4e-146 486.8 17.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_hydro_47 PF01532.15 EMC98902.1 - 5e-169 562.7 0.0 5.8e-169 562.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DAO PF01266.19 EMC98904.1 - 2.1e-28 99.2 2.2 4.6e-28 98.1 1.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC98904.1 - 6.6e-05 22.8 0.1 0.0002 21.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMC98904.1 - 0.00067 18.8 0.9 0.0011 18.0 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMC98904.1 - 0.0018 18.6 1.1 0.004 17.5 0.8 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC98904.1 - 0.003 16.4 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EMC98904.1 - 0.005 16.5 0.3 0.0079 15.8 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EMC98904.1 - 0.0096 15.0 0.2 0.018 14.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMC98904.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMC98904.1 - 0.027 14.6 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EMC98904.1 - 0.031 13.7 1.9 0.06 12.7 0.7 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EMC98904.1 - 0.096 11.5 0.4 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PHD PF00628.24 EMC98905.1 - 3.2e-08 33.1 15.5 3.6e-08 32.9 5.5 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EMC98905.1 - 5.8e-08 32.4 2.6 5.8e-08 32.4 1.8 3.5 3 1 0 3 3 3 1 Ring finger domain PHD_2 PF13831.1 EMC98905.1 - 8.9e-07 28.1 4.3 1.9e-06 27.0 2.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_3 PF13920.1 EMC98905.1 - 1.2e-05 24.9 1.6 1.2e-05 24.9 1.1 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC98905.1 - 1.4e-05 25.1 3.1 1.4e-05 25.1 2.1 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC98905.1 - 1.9e-05 24.2 2.2 1.9e-05 24.2 1.5 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC98905.1 - 2.4e-05 23.9 1.4 2.4e-05 23.9 1.0 3.0 4 1 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC98905.1 - 8.3e-05 22.5 0.6 8.3e-05 22.5 0.4 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC98905.1 - 0.0076 16.0 0.3 0.0076 16.0 0.2 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EMC98905.1 - 0.018 14.5 4.5 0.089 12.3 0.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF3268 PF11672.3 EMC98905.1 - 0.087 12.9 3.9 0.74 9.9 0.2 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3268) zf-RING_4 PF14570.1 EMC98905.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.2 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain PHF5 PF03660.9 EMC98905.1 - 0.24 11.4 6.3 0.53 10.3 0.5 2.8 2 1 1 3 3 2 0 PHF5-like protein DZR PF12773.2 EMC98905.1 - 0.51 10.1 9.0 12 5.8 3.7 3.2 2 1 1 3 3 3 0 Double zinc ribbon zf-PHD-like PF15446.1 EMC98905.1 - 2.8 7.1 8.3 0.32 10.2 1.7 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Ribosomal_L37ae PF01780.14 EMC98906.1 - 9.4e-41 137.5 9.9 1e-40 137.4 6.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Elf1 PF05129.8 EMC98906.1 - 0.00086 18.9 0.3 0.0012 18.4 0.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 EMC98906.1 - 0.0014 18.2 2.3 0.002 17.7 1.6 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EMC98906.1 - 0.0027 17.4 3.8 0.0041 16.8 2.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EMC98906.1 - 0.0065 15.8 4.3 0.016 14.6 0.2 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain zf-BED PF02892.10 EMC98906.1 - 0.021 14.5 6.8 0.34 10.7 0.5 2.4 1 1 1 2 2 2 0 BED zinc finger zf-ribbon_3 PF13248.1 EMC98906.1 - 0.027 13.6 1.8 3.4 7.0 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMC98906.1 - 0.059 13.3 0.9 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EMC98906.1 - 0.06 12.8 1.3 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-FCS PF06467.9 EMC98906.1 - 0.072 12.7 2.9 0.29 10.8 0.4 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2HC5 PF06221.8 EMC98906.1 - 0.13 12.0 2.9 11 5.8 0.1 1.8 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.6 EMC98906.1 - 0.15 11.3 0.9 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 EMC98906.1 - 0.21 11.9 5.7 0.65 10.4 1.1 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Desulfoferrod_N PF06397.7 EMC98906.1 - 0.66 9.4 4.1 2 7.8 0.3 2.2 1 1 1 2 2 2 0 Desulfoferrodoxin, N-terminal domain YhfH PF14149.1 EMC98906.1 - 0.88 9.4 3.2 15 5.5 0.2 2.3 1 1 1 2 2 2 0 YhfH-like protein zf-C2H2 PF00096.21 EMC98906.1 - 0.93 9.9 4.1 5.6 7.5 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-IS66 PF13005.2 EMC98906.1 - 1.2 9.1 4.1 4.1 7.4 0.1 2.3 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-Sec23_Sec24 PF04810.10 EMC98906.1 - 2.1 7.9 5.4 2.3 7.8 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger DUF2688 PF10892.3 EMC98906.1 - 2.1 8.0 5.7 2.5 7.8 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Ribosomal_L44 PF00935.14 EMC98906.1 - 5.4 7.0 11.3 1.8 8.6 4.1 2.3 1 1 1 2 2 2 0 Ribosomal protein L44 Saccharop_dh PF03435.13 EMC98907.1 - 4e-19 68.8 0.0 5.4e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AMP-binding PF00501.23 EMC98908.1 - 1.3e-74 251.0 0.0 1.6e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC98908.1 - 1.6e-13 51.3 0.0 4.9e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHF5 PF03660.9 EMC98909.1 - 5.5e-51 171.1 9.8 6.3e-51 170.9 6.8 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EMC98909.1 - 0.86 9.4 15.3 0.2 11.4 5.5 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EMC98909.1 - 1 9.1 15.4 3 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EMC98909.1 - 7.8 4.0 6.7 7.9 3.9 4.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 EMC98909.1 - 8.5 6.1 15.7 48 3.7 9.8 2.5 1 1 1 2 2 2 0 PHD-finger Pkinase PF00069.20 EMC98910.1 - 3.3e-70 236.2 0.0 4.3e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC98910.1 - 1.8e-37 128.8 0.0 2.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC98910.1 - 0.00042 19.3 0.0 0.0011 18.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EMC98910.1 - 0.13 11.9 0.1 0.5 10.0 0.0 1.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinesin PF00225.18 EMC98913.1 - 5.9e-85 284.9 0.6 2.6e-47 161.1 1.7 2.4 2 0 0 2 2 2 2 Kinesin motor domain ADIP PF11559.3 EMC98913.1 - 0.0018 18.2 6.4 0.0018 18.2 4.5 3.6 1 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding KLRAQ PF10205.4 EMC98913.1 - 0.0019 18.1 4.6 0.0019 18.1 3.2 3.3 2 2 1 3 3 3 1 Predicted coiled-coil domain-containing protein Reo_sigmaC PF04582.7 EMC98913.1 - 0.0046 16.1 13.3 0.022 13.9 1.2 2.5 3 0 0 3 3 3 2 Reovirus sigma C capsid protein LPP PF04728.8 EMC98913.1 - 0.051 13.3 1.5 0.38 10.5 0.4 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ApoO PF09769.4 EMC98913.1 - 2.6 7.7 7.1 6.2 6.5 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein O PspA_IM30 PF04012.7 EMC98913.1 - 7.7 5.8 40.2 6.5 6.0 17.0 3.6 1 1 2 3 3 3 0 PspA/IM30 family Acyltransferase PF01553.16 EMC98914.1 - 7.1e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ank_2 PF12796.2 EMC98915.1 - 5.4e-42 142.0 17.5 3.7e-15 56.0 0.0 8.6 5 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EMC98915.1 - 1.8e-36 122.1 16.0 6e-08 32.1 0.1 9.5 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.1 EMC98915.1 - 1.3e-28 98.3 23.4 1.7e-09 37.6 0.5 11.1 10 2 1 12 12 12 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC98915.1 - 8e-28 96.3 9.8 2.2e-10 40.7 0.1 10.2 10 2 2 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC98915.1 - 5.2e-24 81.9 10.3 2.3e-05 24.1 0.0 7.9 9 0 0 9 9 9 5 Ankyrin repeat SRP72 PF08492.7 EMC98916.1 - 1.1e-15 57.7 8.8 1.1e-15 57.7 6.1 2.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 EMC98916.1 - 0.0042 17.1 10.0 0.43 10.7 2.0 4.7 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EMC98916.1 - 0.018 15.6 27.4 0.046 14.4 0.6 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC98916.1 - 0.046 14.0 24.6 0.65 10.3 0.0 6.4 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC98916.1 - 0.087 12.4 1.6 0.68 9.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC98916.1 - 0.1 12.8 1.2 6.1 7.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC98916.1 - 0.24 12.1 29.3 6.2 7.7 0.1 9.2 8 3 3 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC98916.1 - 2.1 8.9 7.4 67 4.2 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat GST_C PF00043.20 EMC98917.1 - 5.8e-10 39.0 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC98917.1 - 7.6e-07 28.9 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC98917.1 - 1e-06 29.1 0.4 3e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PRCC PF10253.4 EMC98918.1 - 4.4e-25 89.4 12.5 3.3e-24 86.5 8.7 2.5 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Acetyltransf_3 PF13302.1 EMC98919.1 - 2.1e-16 60.3 0.0 3.5e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC98919.1 - 1.3e-12 47.5 0.1 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMC98919.1 - 2.1e-06 27.7 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMC98919.1 - 9.9e-05 22.4 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC98919.1 - 0.0019 17.9 0.1 0.0062 16.2 0.0 1.9 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 EMC98919.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arrestin_N PF00339.24 EMC98920.1 - 1e-13 51.3 0.0 1.9e-09 37.5 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EMC98920.1 - 0.00094 18.4 0.0 0.0031 16.7 0.0 1.7 1 1 1 2 2 2 1 Bul1 C terminus TFIIA PF03153.8 EMC98921.1 - 2.9e-66 224.9 17.0 3.3e-66 224.7 11.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EMC98921.1 - 0.059 11.6 39.3 0.0021 16.4 23.1 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2237 PF09996.4 EMC98922.1 - 3.8e-32 110.2 0.1 7.7e-32 109.2 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) p450 PF00067.17 EMC98923.1 - 1.9e-60 204.7 0.0 2.5e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B_3 PF13483.1 EMC98924.1 - 1.1e-05 25.1 0.1 2.4e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SPRY PF00622.23 EMC98925.1 - 3.6e-05 23.8 0.0 7.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-RING_2 PF13639.1 EMC98926.1 - 4.2e-11 42.4 4.6 8.2e-11 41.5 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC98926.1 - 3.9e-08 33.2 1.6 6.7e-08 32.5 1.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC98926.1 - 6e-06 26.0 0.8 1.5e-05 24.7 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EMC98926.1 - 7.4e-06 25.5 3.0 1.3e-05 24.7 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC98926.1 - 6.5e-05 22.5 2.7 0.00011 21.8 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC98926.1 - 0.00013 21.9 3.7 0.00092 19.1 2.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC98926.1 - 0.0003 20.3 2.5 0.00059 19.4 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1049 PF06305.6 EMC98926.1 - 0.033 13.6 0.7 0.063 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) zf-RING-like PF08746.6 EMC98926.1 - 0.19 11.7 2.0 0.43 10.6 1.4 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EMC98926.1 - 0.31 10.7 2.8 0.59 9.8 1.9 1.5 1 0 0 1 1 1 0 PHD-finger Ada3 PF10198.4 EMC98927.1 - 1.9e-35 121.5 0.3 1.9e-35 121.5 0.2 2.3 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 MFS_1 PF07690.11 EMC98928.1 - 7e-37 126.9 26.5 1.1e-36 126.3 17.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 EMC98928.1 - 0.072 13.2 6.3 0.17 11.9 0.0 3.3 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding Cellulase PF00150.13 EMC98930.1 - 6.7e-17 61.5 1.0 6.7e-17 61.5 0.7 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RecR PF02132.10 EMC98931.1 - 0.066 12.6 1.5 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.1 EMC98931.1 - 3 7.1 5.5 3.5 6.9 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbon domain TEA PF01285.13 EMC98932.1 - 7.4e-29 101.1 0.3 8.1e-29 101.0 0.2 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 EMC98932.1 - 0.0064 16.5 0.1 0.016 15.2 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain dsrm PF00035.20 EMC98934.1 - 5e-08 33.4 2.3 0.024 15.2 0.0 3.8 3 1 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EMC98934.1 - 0.0013 19.0 0.2 0.46 10.7 0.0 3.2 3 0 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 Amidohydro_1 PF01979.15 EMC98935.1 - 1.4e-58 199.1 1.2 2e-58 198.6 0.8 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EMC98935.1 - 4.6e-53 178.4 1.2 1e-52 177.3 0.8 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EMC98935.1 - 8.3e-40 134.6 0.2 2e-39 133.4 0.1 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EMC98935.1 - 1.8e-37 127.3 0.1 4.4e-37 126.0 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit HMG_box PF00505.14 EMC98935.1 - 1.6e-10 41.1 0.8 3.5e-10 39.9 0.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC98935.1 - 1.8e-07 31.4 1.1 3.7e-07 30.4 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain Amidohydro_3 PF07969.6 EMC98935.1 - 1e-05 25.0 0.9 0.00015 21.0 0.0 2.5 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMC98935.1 - 1.3e-05 24.9 3.3 3.9e-05 23.3 2.3 1.9 1 0 0 1 1 1 1 Amidohydrolase Nop14 PF04147.7 EMC98935.1 - 0.0004 18.4 28.8 0.00059 17.9 19.9 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EMC98935.1 - 0.0093 15.2 22.0 0.017 14.4 15.3 1.4 1 0 0 1 1 1 1 SDA1 SGT1 PF07093.6 EMC98935.1 - 8.2 4.6 17.6 12 4.1 12.2 1.2 1 0 0 1 1 1 0 SGT1 protein Pro_isomerase PF00160.16 EMC98936.1 - 6.8e-36 123.8 0.0 1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EMC98936.1 - 2.8e-16 58.9 0.0 5.1e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC98936.1 - 1.1e-10 41.3 0.0 2.3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC98936.1 - 4.3e-09 36.0 0.0 1.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 EMC98938.1 - 7.3e-06 25.7 6.8 1.3e-05 25.0 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF155 PF02582.9 EMC98939.1 - 9.5e-59 198.2 0.0 1.4e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Bromodomain PF00439.20 EMC98940.1 - 7.3e-22 77.0 0.0 1.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EMC98940.1 - 3.5e-10 39.9 0.2 6.8e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC98940.1 - 1.2e-09 38.0 0.1 2e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMC98940.1 - 0.044 13.8 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FA_desaturase PF00487.19 EMC98941.1 - 0.029 13.8 0.8 0.033 13.6 0.6 1.0 1 0 0 1 1 1 0 Fatty acid desaturase UPF0197 PF05251.7 EMC98941.1 - 0.08 13.2 6.2 0.18 12.1 4.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) DoxX_2 PF13564.1 EMC98941.1 - 0.26 11.2 3.6 0.31 11.0 2.5 1.1 1 0 0 1 1 1 0 DoxX-like family Rad1 PF02144.11 EMC98942.1 - 3.8e-78 262.0 0.0 4.3e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 GST_C PF00043.20 EMC98943.1 - 2.6e-08 33.7 0.0 3.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC98943.1 - 2e-06 27.6 0.0 3.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC98943.1 - 1.3e-05 25.5 0.0 2.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC98943.1 - 0.00019 21.5 0.1 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC98943.1 - 0.0038 17.0 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC98943.1 - 0.14 12.3 0.0 0.44 10.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_M16 PF00675.15 EMC98944.1 - 3.9e-58 195.4 1.8 5.8e-58 194.8 0.2 2.0 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMC98944.1 - 1.3e-38 132.5 0.0 3.9e-38 130.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.7 EMC98945.1 - 3e-42 143.3 0.0 3.9e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 CybS EMP70 PF02990.11 EMC98946.1 - 2.3e-156 521.3 0.0 3.3e-156 520.8 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 zf-C3HC4_3 PF13920.1 EMC98948.1 - 0.00038 20.0 9.9 0.00058 19.4 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EMC98948.1 - 0.017 15.0 0.0 0.046 13.6 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-C3HC4_2 PF13923.1 EMC98948.1 - 0.12 12.4 11.3 0.2 11.7 7.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EMC98948.1 - 0.7 9.7 8.0 1.2 8.9 5.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Abhydrolase_3 PF07859.8 EMC98949.1 - 4.2e-25 88.5 0.0 5.9e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMC98949.1 - 5.5e-21 74.6 0.0 9.2e-21 73.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EMC98949.1 - 0.004 15.9 0.3 1.9 7.0 0.0 2.4 3 0 0 3 3 3 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EMC98949.1 - 0.022 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Autoind_synth PF00765.12 EMC98949.1 - 0.03 13.5 0.0 0.91 8.7 0.0 2.2 2 0 0 2 2 2 0 Autoinducer synthetase adh_short PF00106.20 EMC98950.1 - 5.8e-19 68.6 0.0 8e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC98950.1 - 2.6e-06 27.3 0.0 3.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC98950.1 - 1.8e-05 24.4 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 KR domain UPF0113 PF03657.8 EMC98951.1 - 1.1e-08 34.9 0.0 1.7e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EMC98951.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.6 EMC98952.1 - 9.5e-32 109.1 4.0 3e-31 107.5 0.0 3.5 3 1 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 EMC98952.1 - 1.1e-24 86.7 0.0 2.6e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Nucleoporin_FG PF13634.1 EMC98953.1 - 2.6e-33 114.6 244.9 7.9e-10 38.9 37.6 7.0 1 1 5 6 6 6 5 Nucleoporin FG repeat region Nsp1_C PF05064.8 EMC98953.1 - 1.8e-32 111.4 0.0 5.5e-32 109.8 0.0 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region IncA PF04156.9 EMC98953.1 - 0.11 12.1 0.0 6.3 6.3 0.2 2.2 2 0 0 2 2 2 0 IncA protein Dynamitin PF04912.9 EMC98953.1 - 0.31 9.7 1.6 0.33 9.7 0.1 1.6 2 0 0 2 2 2 0 Dynamitin ATG16 PF08614.6 EMC98953.1 - 6.3 6.5 9.6 0.51 10.1 0.0 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EMC98954.1 - 0.0005 19.7 13.2 0.0005 19.7 9.1 3.2 1 1 1 3 3 3 1 IncA protein Tis11B_N PF04553.7 EMC98954.1 - 0.015 15.5 1.0 0.052 13.7 0.7 1.9 1 0 0 1 1 1 0 Tis11B like protein, N terminus Reo_sigmaC PF04582.7 EMC98954.1 - 0.11 11.6 6.3 0.19 10.8 1.2 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EMC98954.1 - 0.32 10.8 39.8 0.22 11.3 12.1 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_trans_2 PF11951.3 EMC98954.1 - 0.82 8.2 7.8 0.061 11.9 1.6 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain GAS PF13851.1 EMC98954.1 - 2.3 7.3 27.0 0.26 10.4 11.0 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 EMC98954.1 - 5.6 7.2 9.0 0.48 10.7 1.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.13 EMC98954.1 - 6.8 6.4 14.6 3.7 7.3 0.4 4.6 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF3176 PF11374.3 EMC98955.1 - 3.7e-26 91.1 0.2 8.4e-26 90.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF1049 PF06305.6 EMC98955.1 - 5.1 6.6 5.6 5 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) NAD_binding_1 PF00175.16 EMC98956.1 - 8.9e-32 109.9 0.0 2.1e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMC98956.1 - 2.4e-21 75.6 0.0 5.9e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMC98956.1 - 3.3e-09 36.8 0.0 0.0001 22.2 0.0 2.5 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMC98956.1 - 0.00097 19.0 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4366 PF14283.1 EMC98956.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) FAD-oxidase_C PF02913.14 EMC98957.1 - 4.2e-55 186.7 0.0 6.5e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMC98957.1 - 1.1e-37 128.5 0.0 2e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.1 EMC98959.1 - 7.5e-21 74.5 0.0 1.1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC98959.1 - 5.7e-10 38.9 0.0 1.6e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC98959.1 - 1.2e-09 38.5 0.0 4.3e-09 36.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC98959.1 - 3.7e-09 37.1 0.0 1.2e-08 35.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC98959.1 - 1.4e-08 35.0 0.0 4.2e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC98959.1 - 0.00053 20.3 0.0 0.0026 18.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC98959.1 - 0.0031 16.9 0.0 0.0081 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMC98959.1 - 0.0033 16.5 0.0 0.0072 15.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMC98959.1 - 0.0074 16.3 0.0 0.053 13.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC98959.1 - 0.0077 15.2 0.0 0.022 13.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 EMC98959.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EMC98959.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EMC98959.1 - 0.029 14.3 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EMC98959.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EMC98959.1 - 0.095 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase HATPase_c PF02518.21 EMC98961.1 - 2.2e-23 82.1 0.0 4.6e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMC98961.1 - 2.8e-23 82.0 0.0 5.3e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EMC98961.1 - 2.1e-12 47.3 0.0 1e-09 38.6 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EMC98961.1 - 3e-08 33.6 0.0 3.6e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold HisKA PF00512.20 EMC98961.1 - 1.1e-07 31.7 2.0 2.9e-07 30.3 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EMC98961.1 - 4.7e-07 29.5 0.0 6.7e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.1 EMC98961.1 - 0.0014 19.0 0.0 0.0041 17.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain PAS_8 PF13188.1 EMC98961.1 - 0.0059 16.4 0.0 0.018 14.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.1 EMC98961.1 - 0.009 16.1 0.0 0.029 14.4 0.0 1.9 1 0 0 1 1 1 1 GAF domain PAS_3 PF08447.6 EMC98961.1 - 0.048 13.7 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 PAS fold Fungal_trans PF04082.13 EMC98962.1 - 7.6e-15 54.4 3.1 1.1e-14 53.9 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC98962.1 - 5.5e-08 32.5 10.5 9.7e-08 31.8 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylsulfotrans PF05935.6 EMC98963.1 - 4.5e-28 98.0 0.2 1.4e-15 56.8 0.0 2.6 1 1 2 3 3 3 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.1 EMC98963.1 - 1.5e-18 66.9 0.0 2.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 EMC98963.1 - 0.00023 20.7 0.2 0.38 10.1 0.0 2.9 2 1 0 3 3 3 2 PQQ-like domain SGL PF08450.7 EMC98963.1 - 0.081 12.2 0.0 11 5.2 0.0 2.6 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region APS-reductase_C PF12139.3 EMC98963.1 - 0.093 12.8 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Adenosine-5'-phosphosulfate reductase beta subunit DUF504 PF04457.7 EMC98963.1 - 0.14 12.3 2.1 17 5.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF504) MFS_1 PF07690.11 EMC98964.1 - 4.6e-34 117.6 17.7 4.6e-34 117.6 12.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC98964.1 - 1.1e-09 37.3 3.2 1.1e-09 37.3 2.2 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter 7TM-7TMR_HD PF07698.6 EMC98964.1 - 0.02 14.3 0.5 0.02 14.3 0.4 3.6 2 2 1 3 3 3 0 7TM receptor with intracellular HD hydrolase Mu-like_Pro PF10123.4 EMC98965.1 - 0.032 13.6 1.2 0.042 13.2 0.8 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein DUF3431 PF11913.3 EMC98968.1 - 4.2e-76 255.3 0.5 4.7e-76 255.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_transf_28 PF03033.15 EMC98969.1 - 3.1e-19 69.1 0.0 1e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMC98969.1 - 5.5e-08 31.8 0.0 8.8e-08 31.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 EMC98969.1 - 0.005 16.9 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 EMC98969.1 - 0.0086 15.7 1.5 0.025 14.2 0.0 2.5 3 0 0 3 3 3 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.15 EMC98969.1 - 1.2 8.9 15.5 2.7 7.8 1.3 4.5 4 0 0 4 4 4 0 Ubiquitin interaction motif Ion_trans_2 PF07885.11 EMC98971.1 - 0.28 10.9 0.2 0.28 10.9 0.1 3.0 3 1 1 4 4 4 0 Ion channel FAD_binding_4 PF01565.18 EMC98973.1 - 2.6e-15 56.1 2.4 4.6e-15 55.3 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMC98973.1 - 5.5e-10 39.0 0.3 5.5e-10 39.0 0.2 2.3 3 0 0 3 3 3 1 Berberine and berberine like SBF PF01758.11 EMC98975.1 - 6.4e-48 162.6 8.3 6.4e-48 162.6 5.7 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family PIG-P PF08510.7 EMC98975.1 - 1.4 8.5 11.7 0.25 10.9 0.3 2.9 3 0 0 3 3 3 0 PIG-P PTR2 PF00854.16 EMC98976.1 - 9.1e-40 136.5 9.0 9.8e-39 133.1 4.8 2.8 2 1 0 2 2 2 1 POT family CcmH PF03918.9 EMC98976.1 - 0.0038 16.2 0.2 0.62 9.0 0.0 2.4 2 0 0 2 2 2 2 Cytochrome C biogenesis protein DUF1469 PF07332.6 EMC98976.1 - 0.07 12.8 0.3 0.07 12.8 0.2 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1469) MASE2 PF05230.6 EMC98976.1 - 6.4 6.8 12.5 1.2 9.1 0.2 3.5 3 0 0 3 3 3 0 MASE2 domain DUF676 PF05057.9 EMC98978.1 - 4.6e-47 160.1 0.0 6.8e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EMC98978.1 - 7e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EMC98978.1 - 9e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.13 EMC98978.1 - 0.027 13.7 0.0 0.17 11.1 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Lipase_2 PF01674.13 EMC98978.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) RNase_T PF00929.19 EMC98979.1 - 1.1e-07 32.3 0.0 1.9e-06 28.2 0.0 2.3 1 1 0 1 1 1 1 Exonuclease MmgE_PrpD PF03972.9 EMC98981.1 - 7e-66 222.2 2.1 8.6e-66 221.9 1.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family OmpA_membrane PF01389.12 EMC98981.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 OmpA-like transmembrane domain AAA_PrkA PF08298.6 EMC98984.1 - 0.041 12.5 0.0 0.058 12.0 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain F-box-like_2 PF13013.1 EMC98986.1 - 0.049 13.3 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 F-box-like domain 14-3-3 PF00244.15 EMC98987.1 - 1.8e-115 383.9 8.4 2.1e-115 383.7 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1539 PF07560.6 EMC98987.1 - 0.021 14.6 0.8 0.073 12.9 0.2 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF3802 PF12290.3 EMC98987.1 - 0.081 13.2 0.9 3 8.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) RRM_1 PF00076.17 EMC98988.1 - 3e-45 151.7 0.0 1.6e-16 59.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC98988.1 - 4.1e-28 97.1 0.0 6.5e-10 38.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC98988.1 - 2.6e-22 78.4 0.0 1.4e-08 34.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC98988.1 - 1.8e-06 27.7 0.0 0.00016 21.5 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EMC98988.1 - 0.00014 21.5 0.0 0.0036 17.0 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EMC98988.1 - 0.051 13.0 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RNA_pol_Rpb2_6 PF00562.23 EMC98989.1 - 5.7e-125 417.0 0.0 8.6e-125 416.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMC98989.1 - 2.6e-60 202.8 0.0 4.5e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMC98989.1 - 2.2e-42 144.6 0.1 4.3e-42 143.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMC98989.1 - 1.4e-28 98.9 0.0 3.4e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EMC98989.1 - 3e-23 81.3 0.1 6.2e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EMC98989.1 - 1.2e-22 79.5 0.8 3e-22 78.3 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.8 EMC98989.1 - 9.8e-21 73.3 1.1 1.8e-20 72.4 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 Cas_TM1802 PF09484.5 EMC98989.1 - 0.089 11.2 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) ADH_N PF08240.7 EMC98990.1 - 1.5e-08 34.3 0.0 4.8e-08 32.7 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC98990.1 - 0.022 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PPO1_DWL PF12142.3 EMC98990.1 - 0.15 11.6 0.4 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Polyphenol oxidase middle domain CsbD PF05532.7 EMC98991.1 - 1.1 9.0 6.6 0.17 11.5 1.8 1.7 2 0 0 2 2 2 0 CsbD-like BAR PF03114.13 EMC98992.1 - 3.9e-56 190.1 8.7 5e-56 189.7 6.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EMC98992.1 - 3.9e-13 48.5 0.1 7e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC98992.1 - 6.9e-13 47.9 0.1 1.2e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC98992.1 - 2.2e-08 33.4 0.0 4.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain APG6 PF04111.7 EMC98992.1 - 3.6 6.5 9.7 8.6 5.2 4.9 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Asp PF00026.18 EMC98993.1 - 2.4e-09 36.8 0.1 3.5e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Rifin_STEVOR PF02009.11 EMC98993.1 - 3.9e-05 23.4 0.0 5.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family TAXi_N PF14543.1 EMC98993.1 - 0.02 14.8 0.7 0.084 12.8 0.1 2.3 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Rax2 PF12768.2 EMC98993.1 - 0.021 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VSP PF03302.8 EMC98993.1 - 0.045 12.3 1.4 0.067 11.8 0.9 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.5 EMC98993.1 - 0.048 12.9 8.7 0.095 12.0 6.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4381 PF14316.1 EMC98993.1 - 0.052 13.6 0.1 0.093 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) P12 PF12669.2 EMC98993.1 - 1.6 8.9 2.9 3 8.1 2.0 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family HOOK PF05622.7 EMC98994.1 - 0.028 12.2 0.2 0.044 11.6 0.1 1.2 1 0 0 1 1 1 0 HOOK protein IncA PF04156.9 EMC98994.1 - 0.04 13.5 0.8 0.2 11.2 0.3 1.9 2 0 0 2 2 2 0 IncA protein TMF_TATA_bd PF12325.3 EMC98994.1 - 0.054 13.2 0.8 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PspA_IM30 PF04012.7 EMC98994.1 - 0.058 12.7 0.1 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 PspA/IM30 family DUF4200 PF13863.1 EMC98994.1 - 0.11 12.4 2.3 0.084 12.8 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_11 PF13086.1 EMC98995.1 - 2.6e-59 200.6 0.0 4.8e-59 199.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EMC98995.1 - 3.4e-56 189.8 0.0 1.4e-55 187.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC98995.1 - 2.2e-13 49.7 0.1 9.3e-13 47.7 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EMC98995.1 - 6.6e-12 45.4 0.1 1.7e-09 37.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EMC98995.1 - 6e-07 28.7 0.1 0.01 14.8 0.1 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EMC98995.1 - 1.1e-05 24.9 0.0 0.0013 18.1 0.0 2.4 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EMC98995.1 - 1.5e-05 24.8 0.0 7.3e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EMC98995.1 - 1.7e-05 24.5 0.0 1.3 8.4 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EMC98995.1 - 0.00017 21.7 0.1 0.002 18.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EMC98995.1 - 0.00018 20.7 0.0 0.028 13.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein TrwB_AAD_bind PF10412.4 EMC98995.1 - 0.0034 16.0 0.0 0.0061 15.2 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EMC98995.1 - 0.0035 16.8 0.0 0.021 14.2 0.0 1.9 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EMC98995.1 - 0.0036 16.7 0.1 0.022 14.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 EMC98995.1 - 0.0038 16.9 0.0 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_16 PF13191.1 EMC98995.1 - 0.0059 16.6 0.1 0.017 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EMC98995.1 - 0.0066 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.1 EMC98995.1 - 0.0098 16.0 0.0 1.1 9.3 0.0 3.2 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain Zot PF05707.7 EMC98995.1 - 0.016 14.7 0.0 0.075 12.4 0.0 2.0 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) UvrD_C PF13361.1 EMC98995.1 - 0.026 14.0 0.0 4.2 6.7 0.0 3.1 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EMC98995.1 - 0.027 14.6 0.1 0.2 11.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.9 EMC98995.1 - 0.033 13.8 0.0 0.4 10.2 0.0 2.4 1 1 0 1 1 1 0 Helicase IstB_IS21 PF01695.12 EMC98995.1 - 0.04 13.3 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 1 0 IstB-like ATP binding protein Herpes_ori_bp PF02399.10 EMC98995.1 - 0.11 10.3 0.0 0.19 9.6 0.0 1.3 1 0 0 1 1 1 0 Origin of replication binding protein F-box-like_2 PF13013.1 EMC98996.1 - 0.1 12.3 0.4 0.18 11.5 0.3 1.6 1 1 0 1 1 1 0 F-box-like domain PIG-F PF06699.6 EMC98997.1 - 3.9e-55 186.7 8.1 4.9e-55 186.4 5.6 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Bacteriocin_IIc PF10439.4 EMC98997.1 - 0.044 13.8 2.2 3.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Romo1 PF10247.4 EMC98997.1 - 0.14 12.3 1.2 17 5.7 0.1 2.4 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.1 EMC98997.1 - 0.2 11.2 5.5 0.79 9.4 3.8 1.8 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EMC98997.1 - 0.26 10.8 4.9 5.8 6.5 0.9 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Laminin_G_1 PF00054.18 EMC98998.1 - 0.03 14.3 0.7 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 Laminin G domain RhoGAP PF00620.22 EMC99001.1 - 7.8e-39 132.7 0.0 1.1e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 EMC99001.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Transthyretin-like family DUF1708 PF08101.6 EMC99001.1 - 0.18 10.6 0.2 5 5.8 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1708) zf-Tim10_DDP PF02953.10 EMC99003.1 - 1.7e-20 72.0 5.8 2.3e-20 71.6 4.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EMC99003.1 - 0.013 14.9 5.6 0.025 14.0 3.8 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Mmp37 PF09139.6 EMC99003.1 - 0.1 11.6 0.2 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 CDC37_N PF03234.9 EMC99003.1 - 0.17 12.2 0.8 0.2 11.9 0.5 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Translin PF01997.11 EMC99004.1 - 3.2e-47 160.7 0.0 3.7e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 EMC99004.1 - 0.026 14.2 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 GMP synthase C terminal domain Met_asp_mut_E PF06368.6 EMC99004.1 - 0.13 10.4 0.0 0.21 9.7 0.0 1.4 1 1 0 1 1 1 0 Methylaspartate mutase E chain (MutE) CCDC155 PF14662.1 EMC99004.1 - 0.18 11.4 3.1 0.38 10.3 0.4 2.2 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 ATP-synt_B PF00430.13 EMC99004.1 - 2.8 7.7 5.6 2.5 7.9 2.7 1.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) NmrA PF05368.8 EMC99005.1 - 1.6e-08 34.0 0.0 3.4e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EMC99005.1 - 2.1e-05 24.6 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding VirC2 PF07181.6 EMC99005.1 - 0.072 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 VirC2 protein Homeobox PF00046.24 EMC99007.1 - 1.2e-13 50.3 1.5 2.1e-13 49.6 1.0 1.4 1 0 0 1 1 1 1 Homeobox domain Amino_oxidase PF01593.19 EMC99008.1 - 1.2e-40 139.9 3.8 3.2e-22 79.2 0.6 3.0 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMC99008.1 - 5.3e-15 55.1 0.2 1.3e-14 53.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC99008.1 - 7.4e-07 29.4 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC99008.1 - 1.5e-06 27.3 0.1 3.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC99008.1 - 3.8e-05 23.8 0.1 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC99008.1 - 0.00042 18.9 0.0 0.0006 18.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EMC99008.1 - 0.00059 18.7 0.2 0.0012 17.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EMC99008.1 - 0.00068 19.4 0.2 0.034 13.9 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EMC99008.1 - 0.00083 18.4 0.2 0.0015 17.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMC99008.1 - 0.0027 16.8 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMC99008.1 - 0.003 17.4 0.1 0.0062 16.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMC99008.1 - 0.009 15.6 0.6 0.021 14.5 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EMC99008.1 - 0.0096 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Flavodoxin_4 PF12682.2 EMC99008.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin UDPG_MGDP_dh_N PF03721.9 EMC99008.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EMC99008.1 - 0.22 10.3 0.4 0.33 9.7 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A COPIIcoated_ERV PF07970.7 EMC99010.1 - 1.8e-35 122.5 0.3 2.7e-35 121.9 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMC99010.1 - 1.2e-23 82.9 0.0 1.9e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PS_Dcarbxylase PF02666.10 EMC99012.1 - 1.4e-50 171.3 0.0 2.3e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EMC99012.1 - 4e-42 141.9 0.5 1e-22 79.7 0.0 3.1 3 0 0 3 3 3 2 C2 domain DUF2731 PF10806.3 EMC99012.1 - 5.2e-05 23.4 0.1 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) EF-hand_1 PF00036.27 EMC99012.1 - 0.0018 17.4 0.0 0.0057 15.8 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EMC99012.1 - 0.0056 16.7 0.1 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair GST_C_3 PF14497.1 EMC99012.1 - 0.015 15.7 0.3 0.045 14.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain EF-hand_6 PF13405.1 EMC99012.1 - 0.018 14.8 0.0 0.066 13.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Syntaxin PF00804.20 EMC99013.1 - 1.5e-10 41.1 16.0 2.9e-10 40.2 4.4 2.2 2 0 0 2 2 2 2 Syntaxin SNARE PF05739.14 EMC99013.1 - 2.2e-10 40.0 5.5 5.4e-10 38.8 3.8 1.7 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 EMC99013.1 - 0.0024 17.4 1.6 0.006 16.1 1.1 1.7 1 0 0 1 1 1 1 Synaptobrevin DUF2077 PF09850.4 EMC99013.1 - 0.087 12.2 2.3 0.1 11.9 0.3 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF805 PF05656.9 EMC99013.1 - 0.19 11.5 1.4 0.31 10.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3018 PF11455.3 EMC99013.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) Thioredoxin_2 PF13098.1 EMC99013.1 - 0.61 10.3 2.4 3.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Allexi_40kDa PF05549.6 EMC99013.1 - 0.88 8.8 9.3 0.1 11.8 1.9 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2951 PF11166.3 EMC99013.1 - 1.3 8.9 5.0 0.16 11.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF4094 PF13334.1 EMC99013.1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) Mod_r PF07200.8 EMC99013.1 - 3.6 7.4 14.3 8.1 6.3 4.0 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Pepsin-I3 PF06394.8 EMC99013.1 - 4 7.1 9.2 0.4 10.3 2.7 2.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain AAA_5 PF07728.9 EMC99014.1 - 3.7e-126 415.5 1.1 1.2e-22 80.1 0.0 10.1 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMC99014.1 - 3.4e-29 101.1 0.0 2.5e-07 30.3 0.0 8.4 9 0 0 9 9 8 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EMC99014.1 - 3.6e-26 91.9 0.5 0.0032 17.6 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC99014.1 - 7.4e-23 81.6 0.0 0.094 13.5 0.0 7.5 7 0 0 7 7 6 5 AAA domain AAA_33 PF13671.1 EMC99014.1 - 1.6e-22 79.9 0.1 0.0078 16.0 0.0 8.0 6 1 0 6 6 6 5 AAA domain Sigma54_activat PF00158.21 EMC99014.1 - 1.2e-19 70.4 1.6 0.011 15.2 0.0 7.2 7 0 0 7 7 7 4 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EMC99014.1 - 1.7e-19 70.2 0.8 0.0038 17.2 0.0 7.0 7 0 0 7 7 6 4 Sigma-54 interaction domain AAA_22 PF13401.1 EMC99014.1 - 9.6e-19 67.8 6.8 0.022 14.9 0.0 8.0 8 0 0 8 8 6 4 AAA domain AAA_18 PF13238.1 EMC99014.1 - 3.9e-18 65.9 4.1 0.031 14.5 0.0 7.7 7 0 0 7 7 7 4 AAA domain AAA_16 PF13191.1 EMC99014.1 - 1.7e-17 63.9 35.9 0.0013 18.7 0.6 10.0 10 0 0 10 10 8 4 AAA ATPase domain AAA_14 PF13173.1 EMC99014.1 - 3.3e-15 56.1 0.0 0.00061 19.6 0.0 7.5 8 0 0 8 8 6 2 AAA domain T2SE PF00437.15 EMC99014.1 - 5.6e-15 54.9 3.8 0.018 13.9 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein Zeta_toxin PF06414.7 EMC99014.1 - 1.1e-13 50.8 6.2 0.05 12.6 0.0 7.5 7 0 0 7 7 7 4 Zeta toxin AAA_19 PF13245.1 EMC99014.1 - 2.5e-13 49.5 10.3 0.15 11.8 0.1 7.1 6 0 0 6 6 6 4 Part of AAA domain RNA_helicase PF00910.17 EMC99014.1 - 1.2e-12 47.9 1.8 0.12 12.6 0.0 6.5 6 0 0 6 6 6 2 RNA helicase ABC_tran PF00005.22 EMC99014.1 - 1.2e-12 48.2 5.0 0.036 14.3 0.0 7.3 7 0 0 7 7 6 3 ABC transporter DUF258 PF03193.11 EMC99014.1 - 1.2e-11 44.0 1.5 0.03 13.5 0.0 5.5 5 0 0 5 5 5 2 Protein of unknown function, DUF258 NACHT PF05729.7 EMC99014.1 - 2e-11 43.8 11.0 0.17 11.5 0.1 7.0 6 0 0 6 6 6 3 NACHT domain Mg_chelatase PF01078.16 EMC99014.1 - 4.8e-11 42.2 6.3 0.078 12.1 0.1 8.5 8 1 1 9 9 9 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EMC99014.1 - 1.5e-10 40.4 1.7 1.2 8.7 0.1 6.4 6 0 0 6 6 6 2 P-loop containing region of AAA domain UPF0079 PF02367.12 EMC99014.1 - 3.6e-10 39.5 6.9 0.098 12.2 0.0 6.4 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EMC99014.1 - 1.9e-09 37.1 1.2 0.078 12.4 0.0 5.1 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EMC99014.1 - 2.3e-09 37.0 5.5 0.46 10.1 0.1 5.6 6 0 0 6 6 5 2 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 EMC99014.1 - 5.7e-09 35.3 2.2 0.75 8.8 0.0 6.3 6 0 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 EMC99014.1 - 5.8e-09 36.4 2.1 0.95 9.9 0.0 6.0 6 0 0 6 6 5 1 Miro-like protein Arch_ATPase PF01637.13 EMC99014.1 - 2.1e-07 30.9 0.0 0.8 9.3 0.0 6.1 6 0 0 6 6 6 1 Archaeal ATPase SRP54 PF00448.17 EMC99014.1 - 2.1e-07 30.5 9.4 0.14 11.6 0.0 5.3 6 0 0 6 6 5 3 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EMC99014.1 - 3.2e-07 30.4 11.3 0.76 9.7 0.0 6.9 7 0 0 7 7 5 2 AAA domain Rad17 PF03215.10 EMC99014.1 - 3.5e-07 29.2 0.0 0.06 12.0 0.0 4.1 4 0 0 4 4 4 2 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 EMC99014.1 - 4.7e-07 29.3 6.7 0.065 12.6 0.0 5.9 7 0 0 7 7 5 2 AAA domain AAA_23 PF13476.1 EMC99014.1 - 3e-06 27.7 4.3 0.039 14.2 0.0 6.1 7 0 0 7 7 5 1 AAA domain AAA_7 PF12775.2 EMC99014.1 - 1.9e-05 23.9 2.7 0.04 12.9 0.0 4.5 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 DEAD PF00270.24 EMC99014.1 - 3e-05 23.5 0.1 2 7.8 0.0 5.3 5 0 0 5 5 4 1 DEAD/DEAH box helicase TIP49 PF06068.8 EMC99014.1 - 6.3e-05 21.8 2.6 0.64 8.6 0.0 5.6 6 0 0 6 6 6 1 TIP49 C-terminus FtsK_SpoIIIE PF01580.13 EMC99014.1 - 7.5e-05 22.2 4.7 0.68 9.3 0.0 4.7 5 0 0 5 5 4 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EMC99014.1 - 0.0002 21.2 0.3 45 4.0 0.0 5.9 6 0 0 6 6 5 0 50S ribosome-binding GTPase SRPRB PF09439.5 EMC99014.1 - 0.00035 19.8 2.4 15 4.7 0.0 5.3 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EMC99014.1 - 0.0011 18.6 5.4 3.5 7.1 0.0 5.7 6 0 0 6 6 6 0 AAA domain NB-ARC PF00931.17 EMC99014.1 - 0.0016 17.3 5.0 5.7 5.7 0.0 5.7 6 0 0 6 6 6 0 NB-ARC domain KaiC PF06745.8 EMC99014.1 - 0.0037 16.4 0.2 8.7 5.3 0.0 4.6 5 0 0 5 5 4 0 KaiC NTPase_1 PF03266.10 EMC99014.1 - 0.011 15.4 12.4 4.4 6.9 0.0 5.1 6 0 0 6 6 4 0 NTPase Septin PF00735.13 EMC99014.1 - 0.021 13.8 0.5 9.6 5.1 0.0 3.8 4 0 0 4 4 4 0 Septin Dynamin_N PF00350.18 EMC99014.1 - 0.041 13.7 0.1 12 5.7 0.0 3.5 3 0 0 3 3 2 0 Dynamin family PhoH PF02562.11 EMC99014.1 - 0.076 12.2 4.6 5.6 6.1 0.1 4.4 5 0 0 5 5 5 0 PhoH-like protein Pox_A32 PF04665.7 EMC99014.1 - 0.33 10.2 0.7 25 4.0 0.0 3.4 4 0 0 4 4 3 0 Poxvirus A32 protein AAA_6 PF12774.2 EMC99014.1 - 0.51 9.8 0.1 1.7e+02 1.6 0.0 4.0 5 0 0 5 5 3 0 Hydrolytic ATP binding site of dynein motor region D1 ATP_bind_1 PF03029.12 EMC99014.1 - 0.53 9.7 9.2 8.8 5.7 0.0 5.3 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EMC99014.1 - 1.2 8.5 14.7 8.5 5.7 0.2 5.8 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EMC99014.1 - 5.7 6.8 0.2 59 3.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain CbiA PF01656.18 EMC99014.1 - 5.9 6.2 8.7 7.5 5.9 0.0 3.6 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_15 PF13175.1 EMC99014.1 - 6.3 5.7 0.0 49 2.7 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain CTK3 PF12243.3 EMC99015.1 - 2e-50 170.0 0.0 2.7e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EMC99015.1 - 5.9e-20 71.0 4.2 1.3e-19 69.9 2.9 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Voltage_CLC PF00654.15 EMC99016.1 - 7.3e-94 314.7 24.9 1.2e-93 313.9 17.3 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EMC99016.1 - 6.1e-07 29.1 0.0 0.0015 18.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain WD40 PF00400.27 EMC99017.1 - 4.3e-52 172.2 8.5 6.9e-11 41.6 0.7 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tmemb_170 PF10190.4 EMC99017.1 - 5.2e-05 23.2 10.2 9.4e-05 22.4 7.1 1.3 1 0 0 1 1 1 1 Putative transmembrane protein 170 eIF2A PF08662.6 EMC99017.1 - 0.00094 18.9 0.1 0.1 12.2 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF914 PF06027.7 EMC99018.1 - 7.2e-96 320.9 15.1 9.3e-96 320.5 10.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) HCV_env PF01539.12 EMC99018.1 - 5.2e-05 22.7 1.7 0.00012 21.5 1.2 1.6 1 0 0 1 1 1 1 Hepatitis C virus envelope glycoprotein E1 EamA PF00892.15 EMC99018.1 - 0.012 15.6 14.8 0.012 15.6 10.2 2.5 2 1 0 2 2 2 0 EamA-like transporter family DUF3659 PF12396.3 EMC99019.1 - 3.4e-17 61.8 1.1 6e-17 61.0 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) SMK-1 PF04802.10 EMC99020.1 - 2.2e-73 245.9 4.4 4.9e-73 244.7 2.7 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Pectate_lyase_3 PF12708.2 EMC99022.1 - 2e-84 283.2 25.1 7.9e-67 225.6 8.0 2.9 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EMC99022.1 - 7.3e-06 25.3 2.4 0.0095 15.3 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase EBP PF05241.7 EMC99024.1 - 2.2e-68 229.0 9.8 2.6e-68 228.8 6.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein FokI_N PF02981.10 EMC99025.1 - 0.17 11.5 0.4 0.18 11.4 0.3 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain CBFD_NFYB_HMF PF00808.18 EMC99026.1 - 1.2e-10 41.2 0.8 3.2e-10 39.8 0.6 1.8 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC99026.1 - 0.023 14.7 0.1 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Aldedh PF00171.17 EMC99027.1 - 1.8e-159 531.0 0.7 2e-159 530.8 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glycos_transf_2 PF00535.21 EMC99028.1 - 2.5e-21 76.0 0.0 1.3e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMC99028.1 - 3.3e-06 27.0 0.4 0.025 14.3 0.0 3.8 2 2 2 4 4 4 2 Glycosyltransferase like family 2 BTB PF00651.26 EMC99029.1 - 5.1e-08 32.8 0.0 7.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RNase_PH PF01138.16 EMC99031.1 - 1.8e-27 96.2 0.0 2.8e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMC99031.1 - 2.4e-06 27.3 0.1 5e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 EMC99032.1 - 2.9e-77 259.6 21.8 3.3e-77 259.5 15.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein COesterase PF00135.23 EMC99033.1 - 3e-73 247.3 1.8 1.3e-66 225.5 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC99033.1 - 2.7e-07 30.3 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 EMC99035.1 - 2.7e-31 108.7 0.9 8.7e-31 107.0 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99035.1 - 1.3e-29 103.6 0.1 1.6e-29 103.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99035.1 - 1.4e-12 47.6 0.4 2.4e-12 46.8 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMC99035.1 - 3e-06 26.8 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMC99035.1 - 0.00035 19.8 0.0 0.00046 19.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EMC99035.1 - 0.0034 17.1 1.4 0.0079 15.9 0.5 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ubie_methyltran PF01209.13 EMC99035.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CDC14 PF08045.6 EMC99036.1 - 2.1e-85 285.9 0.1 2.4e-85 285.7 0.1 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component CMD PF02627.15 EMC99037.1 - 1.4e-10 40.8 0.0 9.9e-10 38.1 0.0 2.1 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family adh_short PF00106.20 EMC99038.1 - 1e-21 77.5 0.2 2.3e-21 76.4 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99038.1 - 1.4e-15 57.7 0.0 3.4e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99038.1 - 2.1e-10 40.5 0.1 3e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC99038.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EMC99038.1 - 0.082 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EMC99038.1 - 0.093 11.9 0.1 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ORC6 PF05460.8 EMC99040.1 - 0.24 10.4 5.8 0.28 10.2 4.0 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) tRNA_anti-codon PF01336.20 EMC99041.1 - 0.012 15.4 0.0 0.097 12.5 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RNase_PH PF01138.16 EMC99042.1 - 1.1e-17 64.6 0.0 3.3e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 CathepsinC_exc PF08773.6 EMC99042.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Cathepsin C exclusion domain eIF-5_eIF-2B PF01873.12 EMC99043.1 - 2.1e-41 140.4 0.1 3.5e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EMC99043.1 - 2.8e-25 88.0 1.1 1e-24 86.2 0.7 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Formyl_trans_N PF00551.14 EMC99044.1 - 4.4e-38 130.6 0.2 5.9e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EMC99044.1 - 2.5e-08 33.2 0.0 6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EMC99044.1 - 7.8e-05 22.3 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 ACT domain GTP_cyclohydro2 PF00925.15 EMC99045.1 - 9.3e-54 181.1 0.0 6.3e-50 168.7 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II G2F PF07474.7 EMC99047.1 - 0.047 13.0 0.0 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 G2F domain Zip PF02535.17 EMC99048.1 - 4.9e-57 193.3 5.4 3e-56 190.7 2.5 2.4 2 1 0 2 2 2 1 ZIP Zinc transporter DUF445 PF04286.7 EMC99048.1 - 0.23 10.9 0.6 0.42 10.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Methyltransf_25 PF13649.1 EMC99049.1 - 3.4e-09 36.9 0.2 6.9e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC99049.1 - 2.7e-05 23.7 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC99049.1 - 0.0078 15.9 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 EMC99050.1 - 6.9e-98 326.4 0.0 1.1e-97 325.7 0.0 1.3 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EMC99050.1 - 2e-05 25.1 0.0 3.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC99050.1 - 0.0003 20.3 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC99050.1 - 0.0031 17.9 0.1 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EMC99050.1 - 0.0033 16.4 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_23 PF13489.1 EMC99050.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EMC99050.1 - 0.032 13.4 0.2 0.13 11.4 0.1 1.9 1 1 1 2 2 2 0 O-methyltransferase Pmp3 PF01679.12 EMC99051.1 - 2.1e-26 91.3 6.2 2.3e-26 91.2 4.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EMC99051.1 - 0.88 9.2 9.3 0.26 10.9 2.3 2.0 2 0 0 2 2 2 0 Conserved TM helix DUF1762 PF08574.5 EMC99052.1 - 4.1e-15 55.9 10.8 4.1e-15 55.9 7.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) Solute_trans_a PF03619.11 EMC99053.1 - 5.6e-32 111.1 3.5 1.1e-31 110.1 2.5 1.5 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Frag1 PF10277.4 EMC99053.1 - 5.7 6.3 11.0 0.12 11.8 1.3 2.5 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family GRAM PF02893.15 EMC99054.1 - 2.5e-17 62.1 0.1 2.2e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 GRAM domain DUF4637 PF15470.1 EMC99054.1 - 0.85 9.2 8.0 4.3 6.9 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4637) Cofilin_ADF PF00241.15 EMC99055.1 - 2.2e-21 76.0 0.0 2.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4472 PF14739.1 EMC99055.1 - 0.11 12.9 0.1 2.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Lactonase PF10282.4 EMC99056.1 - 9.3e-30 103.8 0.0 2.7e-29 102.3 0.0 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 EMC99056.1 - 0.018 14.4 0.0 0.12 11.7 0.0 2.3 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EMC99056.1 - 0.029 14.3 0.1 0.12 12.4 0.1 2.1 1 0 0 1 1 1 0 NHL repeat MFS_1 PF07690.11 EMC99057.1 - 5.1e-32 110.9 36.6 5.1e-32 110.9 25.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily CAF1 PF04857.15 EMC99058.1 - 4.2e-45 154.1 0.0 5.1e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EMC99058.1 - 7.5e-05 22.2 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 1 3'-5' exonuclease Ribonuclease_T2 PF00445.13 EMC99058.1 - 0.14 11.7 0.1 0.32 10.5 0.0 1.5 2 0 0 2 2 2 0 Ribonuclease T2 family DUF4407 PF14362.1 EMC99059.1 - 0.0079 15.1 10.9 0.03 13.2 7.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) SAPS PF04499.10 EMC99059.1 - 0.12 11.0 7.1 0.16 10.5 4.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 EMC99059.1 - 0.9 8.6 12.0 1.4 8.0 8.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1682 PF07946.9 EMC99059.1 - 0.96 8.2 14.8 5.1 5.8 9.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DUF572 PF04502.8 EMC99059.1 - 0.97 8.5 20.1 1.5 7.9 14.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 EMC99059.1 - 1.4 7.3 24.7 2 6.8 17.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Neur_chan_memb PF02932.11 EMC99059.1 - 1.4 8.7 4.4 2.4 7.9 3.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 EMC99059.1 - 1.4 8.7 14.2 2.4 7.9 9.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Menin PF05053.8 EMC99059.1 - 1.9 6.5 11.2 2.6 6.0 7.8 1.1 1 0 0 1 1 1 0 Menin DUF2413 PF10310.4 EMC99059.1 - 2.7 6.7 18.0 3.9 6.1 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DNA_pol_viral_N PF00242.12 EMC99059.1 - 4 6.3 11.3 7.4 5.4 7.9 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CDC73 PF05179.9 EMC99059.1 - 4.2 6.6 10.2 7.3 5.8 7.1 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Pex26 PF07163.7 EMC99059.1 - 4.2 6.1 12.0 0.1 11.5 0.6 2.8 2 1 1 3 3 2 0 Pex26 protein Borrelia_P83 PF05262.6 EMC99059.1 - 4.7 5.3 13.5 6.5 4.8 9.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.9 EMC99059.1 - 6 4.7 16.6 10 4.0 11.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 EMC99059.1 - 7.6 4.0 13.1 10 3.6 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.6 EMC99059.1 - 9.9 5.9 17.1 15 5.3 11.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FUSC PF04632.7 EMC99061.1 - 0.54 8.6 4.2 0.69 8.2 2.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UCH PF00443.24 EMC99064.1 - 6.6e-73 245.1 0.0 1.8e-72 243.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC99064.1 - 2.6e-15 56.6 0.0 2.1e-07 30.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EMC99064.1 - 5.7e-07 29.8 0.0 1.9e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.18 EMC99064.1 - 0.019 14.3 0.0 0.068 12.5 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin family USP7_C2 PF14533.1 EMC99064.1 - 0.17 11.2 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal Abhydrolase_1 PF00561.15 EMC99065.1 - 1.5e-18 67.2 0.0 2.4e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC99065.1 - 2.8e-10 40.4 0.9 3.5e-09 36.8 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMC99065.1 - 0.00058 19.3 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase FCH PF00611.18 EMC99067.1 - 1.5e-27 95.6 0.9 1.2e-25 89.5 0.1 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMC99067.1 - 1.9e-15 56.1 0.1 1.9e-06 27.3 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 EMC99067.1 - 1.5e-14 53.0 0.0 3e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EMC99067.1 - 9.2e-13 47.7 2.0 1.5e-12 47.0 1.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 EMC99067.1 - 3.5e-05 23.1 0.0 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Prok-RING_1 PF14446.1 EMC99067.1 - 0.45 10.2 4.5 0.89 9.3 3.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spo12 PF05032.7 EMC99067.1 - 1 9.0 4.2 2.4 7.8 2.9 1.5 1 0 0 1 1 1 0 Spo12 family PHD PF00628.24 EMC99067.1 - 1.3 8.7 6.2 2.7 7.7 4.3 1.5 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.11 EMC99067.1 - 1.7 8.8 4.9 4.2 7.5 3.4 1.7 1 0 0 1 1 1 0 C1 domain DEAD PF00270.24 EMC99068.1 - 2.9e-32 111.4 0.2 7.7e-32 110.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC99068.1 - 1e-23 82.9 0.1 2.1e-23 81.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EMC99068.1 - 0.033 13.9 1.0 0.063 13.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EMC99068.1 - 0.039 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EMC99068.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ResIII PF04851.10 EMC99068.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ceramidase PF05875.7 EMC99069.1 - 1.1e-70 237.7 7.7 1.3e-70 237.5 5.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF998 PF06197.8 EMC99069.1 - 0.0019 17.5 6.3 0.002 17.4 0.5 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF998) VIT1 PF01988.14 EMC99069.1 - 0.1 12.0 0.2 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 VIT family Glyco_hydro_3 PF00933.16 EMC99070.1 - 3.6e-65 219.9 0.0 6.4e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMC99070.1 - 6.4e-49 166.5 0.2 1.2e-48 165.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMC99070.1 - 1.3e-05 25.0 0.0 3.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Isy1 PF06246.7 EMC99071.1 - 1.3e-86 290.2 3.9 2e-86 289.5 2.7 1.3 1 1 0 1 1 1 1 Isy1-like splicing family Methyltransf_31 PF13847.1 EMC99072.1 - 7.2e-25 87.3 0.0 8.3e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC99072.1 - 2.7e-23 82.2 0.0 4.8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC99072.1 - 5e-16 59.2 0.0 8.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC99072.1 - 5.9e-16 58.7 0.0 8.7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC99072.1 - 9.1e-16 57.6 0.0 1.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMC99072.1 - 5.3e-15 55.6 0.0 9.3e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC99072.1 - 3.7e-12 46.2 0.0 5.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC99072.1 - 1.3e-07 31.5 0.1 2.6e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMC99072.1 - 1.5e-07 30.9 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EMC99072.1 - 8.4e-05 21.7 0.0 0.00026 20.1 0.0 1.7 1 1 1 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EMC99072.1 - 0.00011 21.8 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EMC99072.1 - 0.00011 21.5 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.7 EMC99072.1 - 0.002 17.0 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EMC99072.1 - 0.0035 16.3 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 EMC99072.1 - 0.0045 16.0 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Nol1_Nop2_Fmu PF01189.12 EMC99072.1 - 0.0061 15.9 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EMC99072.1 - 0.076 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase RNA_pol_Rpb1_1 PF04997.7 EMC99073.1 - 5.7e-108 361.1 0.0 1.1e-107 360.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EMC99073.1 - 3.1e-99 331.7 0.0 4.8e-99 331.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EMC99073.1 - 9e-70 233.9 0.0 1.7e-69 233.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EMC99073.1 - 3e-52 177.0 0.2 5.4e-52 176.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EMC99073.1 - 5.2e-44 149.7 0.0 9.7e-44 148.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EMC99073.1 - 1.1e-39 135.2 1.2 2.2e-39 134.2 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EMC99073.1 - 1.9e-34 117.6 0.1 6.2e-34 115.9 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EMC99073.1 - 6.5e-18 63.1 224.0 0.0089 16.0 7.5 16.4 10 2 8 19 19 19 14 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 EMC99074.1 - 1e-11 44.2 6.0 0.0087 15.9 0.6 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EMC99074.1 - 0.00012 21.9 0.3 1.2 8.8 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EMC99074.1 - 0.012 15.0 0.1 0.89 8.9 0.0 2.8 1 1 2 3 3 3 0 PQQ-like domain Apc4_WD40 PF12894.2 EMC99074.1 - 0.055 12.9 0.0 0.45 10.0 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MscS_porin PF12795.2 EMC99075.1 - 0.072 12.3 6.0 6.5 5.9 4.5 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain BMFP PF04380.8 EMC99075.1 - 3.1 8.0 5.8 2.6 8.2 2.6 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity Senescence PF06911.7 EMC99076.1 - 4.3e-41 140.5 2.5 6.8e-41 139.9 1.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein TrkH PF02386.11 EMC99077.1 - 1.2e-89 300.3 10.8 9.3e-85 284.2 2.5 2.1 2 0 0 2 2 2 2 Cation transport protein DUF1509 PF07420.6 EMC99077.1 - 5.2 6.2 10.6 7.1 5.7 6.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) PCI PF01399.22 EMC99078.1 - 7.5e-07 29.4 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 PCI domain Ras PF00071.17 EMC99080.1 - 7.1e-52 175.0 0.0 8.7e-52 174.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC99080.1 - 2.4e-15 57.0 0.0 4.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC99080.1 - 7.2e-05 22.0 0.0 9.4e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.11 EMC99081.1 - 2e-23 82.6 41.4 1.4e-22 79.9 28.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4611 PF15387.1 EMC99081.1 - 0.082 13.0 1.2 0.18 11.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1435 PF07256.7 EMC99081.1 - 0.24 11.4 6.7 0.3 11.0 1.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) DUF2107 PF09880.4 EMC99081.1 - 0.67 9.8 6.7 12 5.8 0.0 3.7 4 0 0 4 4 4 0 Predicted membrane protein (DUF2107) Pkinase PF00069.20 EMC99082.1 - 3.2e-45 154.3 0.0 4.7e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99082.1 - 1.5e-25 89.7 0.0 2.3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Aldo_ket_red PF00248.16 EMC99083.1 - 3.4e-48 163.8 0.0 4.2e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family XH PF03469.9 EMC99083.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 XH domain MCM2_N PF12619.3 EMC99084.1 - 0.2 11.6 7.7 0.31 11.0 5.4 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 MBOAT PF03062.14 EMC99086.1 - 1.3e-19 70.4 13.6 2.7e-19 69.4 9.4 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EMC99086.1 - 2e-05 24.5 1.1 8.1e-05 22.6 0.8 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PDR_CDR PF06422.7 EMC99086.1 - 0.0009 18.8 0.5 0.0031 17.1 0.0 2.1 2 0 0 2 2 2 1 CDR ABC transporter Kelch_5 PF13854.1 EMC99087.1 - 3.2e-26 90.7 2.0 2.2e-07 30.6 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EMC99087.1 - 4e-26 90.5 14.8 4.7e-08 32.6 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EMC99087.1 - 1.8e-24 84.8 1.6 5.3e-06 26.3 0.0 5.5 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EMC99087.1 - 1.9e-22 78.8 6.0 1.1e-06 28.5 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EMC99087.1 - 5.9e-19 67.3 0.2 8.1e-05 22.0 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EMC99087.1 - 3.4e-17 61.4 8.4 6.8e-06 25.6 0.2 5.0 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EMC99087.1 - 6.1e-11 42.2 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 EMC99088.1 - 1.5e-25 88.0 13.8 2.9e-06 26.9 0.1 7.3 6 1 1 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EMC99088.1 - 1e-06 28.6 0.3 0.0014 18.3 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A AMP-binding PF00501.23 EMC99089.1 - 4.1e-80 269.2 0.0 6.4e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EMC99089.1 - 5.1e-60 202.4 0.0 3.4e-59 199.7 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMC99089.1 - 1.1e-35 122.9 6.4 1e-32 113.3 2.5 3.4 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 EMC99089.1 - 4.8e-20 71.9 4.3 8.1e-17 61.4 1.7 3.0 2 1 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EMC99089.1 - 1.2e-18 67.7 0.1 2.5e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC99089.1 - 1.2e-15 57.5 0.9 3e-08 33.4 0.0 3.8 4 2 0 4 4 4 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMC99089.1 - 4.5e-12 46.0 0.0 1.6e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EMC99089.1 - 1e-08 34.2 0.1 5.6e-05 21.9 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMC99089.1 - 4.9e-08 33.1 3.1 1.4e-05 25.2 0.9 3.8 3 1 0 3 3 3 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC99089.1 - 1.6e-07 30.4 1.7 0.00031 19.7 0.0 3.6 4 0 0 4 4 4 2 RmlD substrate binding domain AMP-binding_C PF13193.1 EMC99089.1 - 0.00062 20.6 1.7 0.0029 18.5 0.2 3.0 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 EMC99089.1 - 0.0013 17.7 3.3 0.16 10.8 0.1 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EMC99089.1 - 0.14 12.0 2.0 0.44 10.3 1.4 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EMC99089.1 - 0.15 11.2 1.8 5.1 6.2 0.9 3.2 4 0 0 4 4 4 0 NmrA-like family Glyco_hydro_30 PF02055.11 EMC99090.1 - 4.4e-16 58.1 0.2 4.9e-09 34.9 0.2 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EMC99090.1 - 3.7e-11 42.5 2.2 2.8e-09 36.3 0.0 2.7 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Pmp3 PF01679.12 EMC99094.1 - 3.5e-11 42.6 8.7 4.4e-11 42.3 6.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Squash PF00299.13 EMC99094.1 - 0.47 10.3 2.9 0.95 9.3 2.0 1.5 1 0 0 1 1 1 0 Squash family serine protease inhibitor GFO_IDH_MocA PF01408.17 EMC99095.1 - 4.9e-20 72.2 0.0 7.6e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3136 PF11334.3 EMC99095.1 - 0.027 13.8 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) ADH_N PF08240.7 EMC99096.1 - 1.5e-26 92.3 0.8 3.2e-26 91.2 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC99096.1 - 6.7e-15 54.7 0.0 1.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EMC99096.1 - 0.0046 17.0 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMC99096.1 - 0.045 13.1 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EMC99096.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF687 PF05095.7 EMC99097.1 - 0.017 13.5 0.0 0.033 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF687) ubiquitin PF00240.18 EMC99098.1 - 4.6e-16 57.9 0.0 7.8e-16 57.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMC99098.1 - 2.6e-08 33.4 2.5 7.6e-08 31.9 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EMC99098.1 - 2.3e-05 23.9 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMC99098.1 - 0.00026 21.1 0.0 0.00048 20.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMC99098.1 - 0.00062 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ADH_zinc_N PF00107.21 EMC99099.1 - 4.3e-32 110.4 0.0 8.6e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YEATS PF03366.11 EMC99099.1 - 4.1e-11 42.4 0.1 8.2e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 YEATS family ADH_zinc_N_2 PF13602.1 EMC99099.1 - 7.5e-09 36.5 0.0 1.7e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-RING_2 PF13639.1 EMC99099.1 - 5.8e-07 29.2 2.8 1.8e-06 27.6 2.0 1.8 1 1 0 1 1 1 1 Ring finger domain ADH_N PF08240.7 EMC99099.1 - 7.1e-07 28.9 0.0 2.3e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-C3HC4_2 PF13923.1 EMC99099.1 - 8.9e-07 28.8 2.2 2.5e-06 27.4 1.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC99099.1 - 3.9e-06 26.6 4.7 5.1e-06 26.2 1.4 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMC99099.1 - 1.3e-05 24.7 1.1 1.3e-05 24.7 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC99099.1 - 2.1e-05 24.1 1.3 5.6e-05 22.7 0.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC99099.1 - 4.7e-05 22.9 2.5 0.0001 21.9 1.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC99099.1 - 0.013 15.2 0.9 0.013 15.2 0.7 1.8 2 0 0 2 2 2 0 RING-type zinc-finger AlaDh_PNT_C PF01262.16 EMC99099.1 - 0.15 11.6 0.3 0.37 10.3 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-rbx1 PF12678.2 EMC99099.1 - 3.8 7.6 6.1 3 8.0 1.5 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EMC99099.1 - 6.4 6.4 7.4 35 4.0 2.9 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Nucleopor_Nup85 PF07575.8 EMC99101.1 - 1.6e-21 76.2 0.2 2.4e-09 35.9 0.1 3.3 2 2 0 2 2 2 2 Nup85 Nucleoporin TPR_16 PF13432.1 EMC99101.1 - 0.025 15.2 0.9 0.35 11.5 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC99101.1 - 0.19 12.4 4.3 2.5 8.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.23 EMC99102.1 - 3.8e-79 266.0 0.0 4.9e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC99102.1 - 1.1e-12 48.6 0.0 2.7e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 EMC99103.1 - 9e-27 94.0 0.6 1.5e-25 90.0 0.4 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC99103.1 - 1e-06 27.9 1.1 0.0073 15.2 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMC99103.1 - 0.00057 18.6 0.1 0.079 11.5 0.1 2.8 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.5 EMC99103.1 - 0.0013 17.6 0.0 0.88 8.3 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.22 EMC99103.1 - 0.0077 16.6 0.0 0.75 10.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC99103.1 - 0.022 13.6 0.4 3.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EMC99103.1 - 0.052 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EMC99103.1 - 0.063 13.0 1.1 0.22 11.2 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EMC99103.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Alpha_E3_glycop PF01563.11 EMC99104.1 - 0.045 13.5 1.0 0.053 13.3 0.7 1.1 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein DUF500 PF04366.7 EMC99106.1 - 1.9e-45 153.3 0.0 3.9e-45 152.3 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF155 PF02582.9 EMC99107.1 - 2.9e-54 183.6 1.3 4.6e-54 182.9 0.9 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SH3_9 PF14604.1 EMC99108.1 - 6.2e-16 57.7 0.4 6.2e-16 57.7 0.3 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC99108.1 - 5.8e-14 51.2 0.2 1.4e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC99108.1 - 1.3e-13 50.1 0.3 2.6e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EMC99108.1 - 4.8e-12 45.8 5.9 9.7e-12 44.8 4.2 1.4 2 0 0 2 2 2 1 BAR domain DRY_EERY PF09750.4 EMC99108.1 - 0.26 11.3 6.1 0.52 10.4 4.2 1.5 1 0 0 1 1 1 0 Alternative splicing regulator Macoilin PF09726.4 EMC99108.1 - 4 5.5 9.8 6.5 4.9 6.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Fib_alpha PF08702.5 EMC99108.1 - 4.7 7.3 7.7 8.5 6.4 5.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PI3_PI4_kinase PF00454.22 EMC99109.1 - 1.1e-31 110.1 0.0 1.8e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EMC99109.1 - 2.8e-16 59.0 0.0 5.9e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Soyouz_module PF14313.1 EMC99109.1 - 0.0098 15.4 0.3 0.064 12.8 0.1 2.2 2 0 0 2 2 2 1 N-terminal region of Paramyxovirinae phosphoprotein (P) PI3Ka PF00613.15 EMC99109.1 - 0.18 10.9 0.4 0.35 10.0 0.2 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PCI PF01399.22 EMC99110.1 - 0.00044 20.5 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain BTB PF00651.26 EMC99111.1 - 1.3e-06 28.3 0.0 4.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain SPO11_like PF03533.9 EMC99112.1 - 0.12 12.2 0.2 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 SPO11 homologue Cu_amine_oxid PF01179.15 EMC99114.1 - 3.3e-96 322.5 1.7 4.1e-96 322.2 1.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EMC99114.1 - 6e-15 54.8 0.1 2e-14 53.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EMC99114.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain CTP_synth_N PF06418.9 EMC99115.1 - 4.9e-112 373.5 0.2 6.3e-112 373.1 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EMC99115.1 - 3.8e-51 173.2 0.0 5.8e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMC99115.1 - 6e-08 32.3 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EMC99115.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Aldo_ket_red PF00248.16 EMC99116.1 - 1.4e-55 188.0 0.0 1.7e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Velvet PF11754.3 EMC99118.1 - 2.5e-52 177.4 0.0 2.9e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Velvet factor SE PF08491.5 EMC99120.1 - 5e-104 346.9 0.0 6.2e-104 346.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EMC99120.1 - 1.1e-11 44.4 0.0 2.4e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC99120.1 - 1.4e-10 40.6 1.1 7.1e-07 28.4 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC99120.1 - 3.5e-05 22.8 4.4 0.0018 17.1 1.4 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EMC99120.1 - 5.5e-05 23.1 0.1 0.0001 22.2 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC99120.1 - 0.0004 19.5 0.1 0.00086 18.4 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EMC99120.1 - 0.0011 18.0 0.4 0.077 11.8 0.4 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMC99120.1 - 0.0016 18.4 0.8 0.004 17.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EMC99120.1 - 0.002 17.0 0.8 0.0068 15.3 0.6 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EMC99120.1 - 0.0052 17.1 0.4 0.012 15.9 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC99120.1 - 0.006 15.6 4.0 0.01 14.9 2.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 EMC99120.1 - 0.017 14.5 0.4 0.03 13.7 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EMC99120.1 - 0.018 15.1 0.1 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EMC99120.1 - 0.069 11.7 3.4 0.49 8.9 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 EMC99120.1 - 0.075 11.4 0.3 0.11 10.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EMC99120.1 - 0.078 12.6 0.2 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMC99120.1 - 0.24 10.7 0.4 0.73 9.1 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GMC_oxred_N PF00732.14 EMC99120.1 - 0.24 10.5 0.3 9.1 5.3 0.1 2.5 3 0 0 3 3 3 0 GMC oxidoreductase ThiF PF00899.16 EMC99120.1 - 0.25 11.1 1.4 0.54 10.0 1.0 1.5 1 0 0 1 1 1 0 ThiF family AF-4 PF05110.8 EMC99120.1 - 0.27 9.0 0.0 0.37 8.5 0.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-C3HC4 PF00097.20 EMC99121.1 - 7.4e-09 35.1 5.3 7.4e-09 35.1 3.7 5.4 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 EMC99121.1 - 2.8e-08 33.2 0.6 2.7e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_2 PF13639.1 EMC99121.1 - 2e-07 30.7 6.4 2e-07 30.7 4.4 4.7 4 1 0 4 4 4 1 Ring finger domain SH3_1 PF00018.23 EMC99121.1 - 1.6e-06 27.4 0.0 3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain zf-RING_6 PF14835.1 EMC99121.1 - 2.2e-05 24.1 0.3 2.2e-05 24.1 0.2 3.3 4 0 0 4 4 4 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EMC99121.1 - 3.3e-05 23.8 5.5 3.3e-05 23.8 3.8 4.8 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC99121.1 - 6.7e-05 22.5 5.4 6.7e-05 22.5 3.8 5.4 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC99121.1 - 0.00031 20.5 5.5 0.00031 20.5 3.8 5.2 4 2 1 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC99121.1 - 0.0008 19.0 1.9 0.0008 19.0 1.3 2.6 3 0 0 3 3 3 1 RING-type zinc-finger Methyltransf_9 PF08003.6 EMC99121.1 - 0.2 10.3 0.1 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PLA2_B PF01735.13 EMC99122.1 - 1.9e-108 362.7 4.3 2.4e-108 362.4 3.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain adh_short_C2 PF13561.1 EMC99123.1 - 7.1e-20 71.7 0.1 9.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC99123.1 - 1.4e-17 64.1 2.7 1.9e-17 63.7 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC99123.1 - 0.00078 19.1 3.6 0.01 15.5 2.5 2.1 1 1 0 1 1 1 1 KR domain ArfGap PF01412.13 EMC99124.1 - 8.7e-30 102.9 0.1 1.5e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SAP PF02037.22 EMC99125.1 - 0.0011 18.4 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 SAP domain PAT1 PF09770.4 EMC99127.1 - 8.7 4.4 17.2 11 4.0 12.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Amidohydro_1 PF01979.15 EMC99128.1 - 3e-16 59.9 0.6 1.9e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMC99128.1 - 2e-10 40.3 0.1 1e-08 34.8 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_4 PF13147.1 EMC99128.1 - 2.1e-09 37.8 7.7 5.7e-07 29.8 5.3 2.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC99128.1 - 0.00011 21.5 4.6 0.00086 18.6 2.2 2.7 1 1 1 2 2 2 1 Amidohydrolase family Peptidase_M48 PF01435.13 EMC99129.1 - 4.7e-39 134.2 0.0 8e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 zf-RING_2 PF13639.1 EMC99130.1 - 7.3e-12 44.9 8.2 1.2e-11 44.2 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC99130.1 - 1.1e-08 34.5 5.7 1.6e-08 34.0 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC99130.1 - 2.5e-07 30.5 7.5 3.9e-07 29.9 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC99130.1 - 3e-06 26.8 7.1 4.6e-06 26.2 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC99130.1 - 3.9e-06 26.4 8.2 6.3e-06 25.7 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC99130.1 - 3e-05 24.0 3.3 6.7e-05 22.9 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EMC99130.1 - 0.011 15.1 4.6 0.03 13.8 3.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 UPF0547 PF10571.4 EMC99130.1 - 0.029 14.0 1.5 0.07 12.8 1.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-Apc11 PF12861.2 EMC99130.1 - 0.24 11.2 4.9 0.52 10.1 3.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EMC99130.1 - 0.4 10.4 4.3 0.75 9.5 2.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EMC99130.1 - 0.4 10.5 2.4 0.8 9.5 1.7 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EMC99130.1 - 0.84 9.2 7.8 1.8 8.1 5.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMC99130.1 - 0.93 9.4 8.5 2.6 7.9 5.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EMC99130.1 - 2.3 8.2 8.3 14 5.6 5.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain ETF PF01012.16 EMC99131.1 - 1e-37 129.3 0.6 1.4e-37 128.9 0.4 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain RRM_1 PF00076.17 EMC99132.1 - 2.3e-29 100.8 0.0 4.1e-15 55.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC99132.1 - 1.7e-22 79.1 0.0 4.7e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC99132.1 - 3.1e-10 39.7 0.0 6.9e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EMC99132.1 - 0.026 14.1 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain DLIC PF05783.6 EMC99132.1 - 4.1 5.9 5.1 10 4.6 0.2 2.6 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) Flavodoxin_1 PF00258.20 EMC99133.1 - 5.7e-28 97.7 0.0 9.7e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EMC99133.1 - 6.9e-23 81.2 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EMC99133.1 - 3.1e-14 53.4 0.0 1.7e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EMC99133.1 - 0.0059 16.5 0.0 0.12 12.3 0.0 2.4 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_3 PF12641.2 EMC99133.1 - 0.017 14.5 0.0 0.069 12.5 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain HET PF06985.6 EMC99134.1 - 8.6e-23 81.0 0.2 1e-22 80.7 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 7kD_coat PF02495.12 EMC99134.1 - 0.083 12.3 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 7kD viral coat protein Dynein_light PF01221.13 EMC99135.1 - 4.8e-38 129.0 3.0 5.3e-38 128.9 2.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 EMC99135.1 - 0.12 12.7 0.2 0.14 12.4 0.2 1.2 1 0 0 1 1 1 0 Ground-like domain RRM_1 PF00076.17 EMC99136.1 - 1.9e-73 242.0 0.5 2.7e-19 68.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC99136.1 - 2.3e-64 213.3 0.2 6.6e-15 54.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC99136.1 - 2.8e-38 129.5 0.0 1.3e-07 31.3 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC99136.1 - 4e-09 36.1 0.7 0.28 10.9 0.0 5.4 5 1 0 5 5 5 3 Limkain b1 Nup35_RRM_2 PF14605.1 EMC99136.1 - 7.1e-05 22.4 0.0 4.9 7.0 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMC99136.1 - 0.0009 19.0 1.5 18 5.2 0.0 5.1 5 0 0 5 5 5 1 RNA binding motif Amidohydro_1 PF01979.15 EMC99137.1 - 2.8e-20 73.2 0.1 5.9e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMC99137.1 - 3.2e-15 55.6 0.0 9.3e-15 54.2 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC99137.1 - 3.5e-08 33.0 3.6 3.7e-05 23.1 0.1 3.5 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMC99137.1 - 2.6e-06 27.6 1.9 0.00089 19.3 1.3 2.7 1 1 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EMC99138.1 - 9.9e-44 149.5 0.0 1.9e-43 148.6 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF1900 PF08954.6 EMC99139.1 - 4.9e-51 171.8 0.0 9e-50 167.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EMC99139.1 - 6.7e-35 118.5 0.0 1.2e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EMC99139.1 - 1.4e-24 85.0 8.8 8e-08 31.8 0.1 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EMC99139.1 - 0.00012 20.3 0.1 0.12 10.4 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Rotamase PF00639.16 EMC99141.1 - 5.4e-19 68.7 0.0 7.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EMC99141.1 - 2.6e-13 50.2 0.0 3.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EMC99141.1 - 3.5e-10 39.5 1.3 3.5e-10 39.5 0.9 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EMC99141.1 - 0.00028 21.4 0.0 0.00045 20.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain TFIIS_C PF01096.13 EMC99142.1 - 8.7e-12 44.4 6.9 8.7e-12 44.4 4.8 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMC99142.1 - 4.5e-09 35.8 2.4 4.5e-09 35.8 1.7 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit RRN7 PF11781.3 EMC99142.1 - 0.076 12.5 0.2 0.076 12.5 0.2 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EMC99142.1 - 0.61 9.9 14.8 0.24 11.2 1.0 3.0 2 1 0 2 2 2 0 Double zinc ribbon Churchill PF06573.6 EMC99142.1 - 1.7 8.6 7.6 0.64 10.0 0.7 2.3 2 1 0 2 2 2 0 Churchill protein zf-C4pol PF14260.1 EMC99142.1 - 2.7 8.0 10.5 6 6.9 0.4 3.0 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Lar_restr_allev PF14354.1 EMC99142.1 - 3 8.2 9.8 0.8 10.0 0.8 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EMC99142.1 - 6.9 6.0 8.8 11 5.3 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain PolC_DP2 PF03833.8 EMC99142.1 - 9.3 3.7 8.2 5.7 4.4 0.9 2.0 1 1 0 2 2 2 0 DNA polymerase II large subunit DP2 SET PF00856.23 EMC99144.1 - 5.4e-09 36.5 0.0 5.4e-09 36.5 0.0 4.3 3 1 0 3 3 3 1 SET domain Ribosomal_L14 PF00238.14 EMC99145.1 - 2.8e-45 152.9 1.2 3.3e-45 152.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Anillin PF08174.6 EMC99146.1 - 3.7e-26 91.8 0.9 1.2e-25 90.1 0.0 2.3 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 EMC99146.1 - 2.5e-10 40.4 0.0 6.4e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC99146.1 - 3.5e-05 23.9 0.0 9.3e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EMC99146.1 - 0.045 13.9 0.1 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_M26_C PF07580.9 EMC99146.1 - 0.11 10.7 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region DEAD PF00270.24 EMC99148.1 - 4.1e-33 114.2 0.2 9.9e-33 113.0 0.0 1.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC99148.1 - 4.9e-14 51.9 0.0 2.7e-13 49.5 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC99148.1 - 0.0043 16.8 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMC99148.1 - 0.0063 15.3 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain adh_short PF00106.20 EMC99149.1 - 1e-18 67.8 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMC99149.1 - 3.2e-05 23.4 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMC99149.1 - 4.8e-05 23.2 0.0 6.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99149.1 - 0.0003 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMC99149.1 - 0.006 15.3 0.0 0.0076 14.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMC99149.1 - 0.027 14.4 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding UCH PF00443.24 EMC99150.1 - 5.9e-41 140.3 0.0 1.1e-40 139.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC99150.1 - 9.9e-16 58.0 0.0 7.6e-15 55.1 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1796 PF08795.5 EMC99150.1 - 0.046 13.3 1.6 0.095 12.3 0.0 2.3 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) Glutaminase PF04960.10 EMC99150.1 - 0.12 11.3 0.2 0.33 9.8 0.1 1.7 2 0 0 2 2 2 0 Glutaminase Ribosomal_L18ae PF01775.12 EMC99152.1 - 3e-48 162.8 2.4 3.7e-48 162.5 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Methyltransf_16 PF10294.4 EMC99154.1 - 0.003 17.0 0.0 0.66 9.4 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase adh_short PF00106.20 EMC99155.1 - 9.4e-16 58.1 0.2 1.2e-14 54.5 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99155.1 - 6.8e-07 29.2 0.1 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99155.1 - 3.2e-06 26.9 0.3 9.1e-06 25.4 0.1 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMC99155.1 - 7.4e-05 22.8 0.2 0.00052 20.0 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding AAA_33 PF13671.1 EMC99157.1 - 0.043 13.7 0.1 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.1 EMC99158.1 - 0.0017 18.5 11.2 0.0084 16.3 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC99158.1 - 0.0024 18.0 11.9 0.042 14.1 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC99158.1 - 0.0029 17.6 9.4 0.084 13.0 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMC99158.1 - 0.015 15.6 16.3 0.04 14.2 0.9 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type YrzO PF14142.1 EMC99158.1 - 0.19 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 YrzO-like protein zf-C2H2_6 PF13912.1 EMC99158.1 - 3.5 7.6 7.6 0.41 10.6 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Amidase PF01425.16 EMC99159.1 - 1.2e-82 278.1 0.0 1.5e-82 277.8 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF421 PF04239.7 EMC99160.1 - 0.035 13.6 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF421) WD40 PF00400.27 EMC99162.1 - 2e-12 46.4 0.4 0.00015 21.5 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat UQ_con PF00179.21 EMC99163.1 - 1.2e-45 154.3 0.0 1.6e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMC99163.1 - 0.0024 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EMC99163.1 - 0.0083 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B SBDS PF01172.13 EMC99165.1 - 1e-22 79.7 0.1 1.1e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3328 PF11807.3 EMC99166.1 - 1.2e-30 106.8 0.0 1.7e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ca_hom_mod PF14798.1 EMC99166.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator PPP4R2 PF09184.6 EMC99167.1 - 3.4e-09 36.6 0.0 3.4e-09 36.6 0.0 2.7 3 1 0 3 3 3 1 PPP4R2 CLTH PF10607.4 EMC99168.1 - 9.7e-32 109.6 0.0 2.8e-31 108.1 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EMC99168.1 - 3.5e-24 85.2 0.1 6.4e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EMC99168.1 - 1.2e-05 24.8 0.1 3.7e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 LisH INO80_Ies4 PF08193.6 EMC99169.1 - 7.7e-48 163.3 17.0 1e-47 162.9 11.8 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Glyco_hydro_18 PF00704.23 EMC99170.1 - 7.6e-21 74.9 0.0 1.2e-20 74.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.11 EMC99171.1 - 5.9e-47 160.0 35.4 5.7e-42 143.6 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EMC99171.1 - 1.3e-05 23.5 8.4 1.3e-05 23.5 5.9 2.9 2 1 1 3 3 3 1 Transmembrane secretion effector MFS_2 PF13347.1 EMC99171.1 - 0.0071 14.7 36.1 0.094 11.0 8.7 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein SHS2_Rpb7-N PF03876.12 EMC99172.1 - 3.4e-07 30.2 0.0 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GATase PF00117.23 EMC99173.1 - 1.9e-48 164.4 0.0 2.6e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EMC99173.1 - 4.7e-46 155.5 0.0 1.7e-45 153.7 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EMC99173.1 - 5.2e-08 32.6 0.1 4.8e-06 26.1 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 FGGY_C PF02782.11 EMC99174.1 - 2.2e-72 242.8 0.9 4.4e-72 241.8 0.6 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMC99174.1 - 3.3e-62 209.9 0.0 4.8e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 EMC99176.1 - 1.1e-39 136.2 4.0 1.4e-39 135.9 2.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Tropomyosin_1 PF12718.2 EMC99177.1 - 0.0056 16.5 19.1 0.0056 16.5 13.2 4.7 2 2 1 3 3 3 1 Tropomyosin like DUF3394 PF11874.3 EMC99177.1 - 0.075 12.5 1.7 0.22 11.0 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Reo_sigmaC PF04582.7 EMC99177.1 - 0.28 10.3 12.7 0.18 10.9 3.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IFT46_B_C PF12317.3 EMC99177.1 - 0.35 10.1 2.3 1.4 8.2 0.3 2.5 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF1664 PF07889.7 EMC99177.1 - 1.5 8.5 11.9 6.9 6.4 0.5 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) CsbD PF05532.7 EMC99178.1 - 2.2e-16 59.2 14.3 4.1e-10 39.1 0.3 3.2 3 0 0 3 3 3 2 CsbD-like UPF0444 PF15475.1 EMC99178.1 - 0.16 12.0 1.8 0.28 11.2 0.1 2.1 2 1 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Fungal_trans PF04082.13 EMC99179.1 - 3.9e-29 101.3 0.0 6.4e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC99179.1 - 2.6e-07 30.4 15.5 4.6e-07 29.6 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Engrail_1_C_sig PF10525.4 EMC99179.1 - 0.96 8.6 3.7 0.86 8.7 0.8 2.1 2 0 0 2 2 2 0 Engrailed homeobox C-terminal signature domain SET PF00856.23 EMC99180.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 0 SET domain DUF1212 PF06738.7 EMC99182.1 - 2.2e-50 170.8 17.1 4.8e-50 169.7 0.0 3.1 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EMC99182.1 - 2.4e-20 72.8 14.6 2.5e-14 53.3 2.6 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF3815) NAD_kinase PF01513.16 EMC99183.1 - 4.9e-70 235.5 0.0 6.2e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DSPn PF14671.1 EMC99184.1 - 3.3e-41 140.5 0.0 7.9e-38 129.6 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EMC99184.1 - 1.5e-15 56.9 0.0 3.7e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC99184.1 - 9.7e-06 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3439 PF11921.3 EMC99184.1 - 0.17 11.6 2.4 0.41 10.3 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PTPA PF03095.10 EMC99185.1 - 6e-106 353.9 0.0 7.2e-106 353.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MFS_1 PF07690.11 EMC99186.1 - 9e-46 156.1 27.9 9e-46 156.1 19.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC99186.1 - 1.1e-08 34.1 26.2 7.2e-08 31.4 18.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMC99186.1 - 4.9e-08 31.6 2.3 7.5e-08 31.0 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 EMC99186.1 - 0.062 13.0 4.0 0.13 12.0 1.3 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) Nup188 PF10487.4 EMC99187.1 - 2.6e-23 81.9 0.0 2.9e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 CLTH PF10607.4 EMC99190.1 - 1e-26 93.3 0.0 5e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EMC99190.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 LisH DUF484 PF04340.7 EMC99190.1 - 0.17 11.3 7.0 0.052 13.0 2.9 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF484 Apc15p PF05841.6 EMC99190.1 - 0.35 11.6 3.3 0.69 10.6 2.3 1.4 1 0 0 1 1 1 0 Apc15p protein TPR_4 PF07721.9 EMC99190.1 - 1.3 9.6 5.2 24 5.7 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L22e PF01776.12 EMC99191.1 - 1.2e-44 150.8 0.1 1.4e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1160 PF06648.6 EMC99191.1 - 0.094 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) NmrA PF05368.8 EMC99192.1 - 2.6e-14 53.0 0.0 3.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC99192.1 - 7.2e-14 52.1 0.5 1.3e-13 51.3 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC99192.1 - 3.2e-05 23.4 0.2 5e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC99192.1 - 0.0025 16.5 0.1 0.0047 15.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EMC99192.1 - 0.0043 16.9 0.3 0.0086 15.9 0.2 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMC99192.1 - 0.021 15.1 0.2 0.044 14.0 0.2 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EMC99192.1 - 0.043 12.6 0.2 0.065 12.1 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CoA_binding PF02629.14 EMC99192.1 - 0.07 13.6 0.0 4.3 7.9 0.0 3.2 4 0 0 4 4 3 0 CoA binding domain NAD_binding_4 PF07993.7 EMC99192.1 - 0.071 12.0 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein F420_oxidored PF03807.12 EMC99192.1 - 0.09 13.2 0.3 0.24 11.8 0.2 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 EMC99192.1 - 0.14 12.0 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 EMC99192.1 - 0.17 11.7 0.4 0.34 10.7 0.3 1.5 1 1 0 1 1 1 0 ThiF family AA_permease_2 PF13520.1 EMC99193.1 - 7.2e-53 179.6 50.8 9e-53 179.3 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC99193.1 - 9.5e-21 73.6 38.8 1.2e-20 73.3 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.21 EMC99194.1 - 0.0039 17.4 3.5 0.6 10.5 0.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC99194.1 - 3.8 8.0 16.1 3.9 8.0 0.9 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger GSHPx PF00255.14 EMC99197.1 - 3.8e-39 132.4 0.1 4.7e-39 132.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EMC99197.1 - 2.4e-05 24.0 0.0 0.0001 21.9 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMC99197.1 - 0.00068 19.1 0.1 0.0012 18.4 0.1 1.5 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EMC99197.1 - 0.0019 17.8 0.0 0.039 13.5 0.0 2.5 2 1 1 3 3 3 1 SCO1/SenC NOG1 PF06858.9 EMC99197.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) FAD_binding_3 PF01494.14 EMC99198.1 - 1.8e-16 60.1 0.3 6.6e-15 55.0 0.2 2.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EMC99198.1 - 0.0011 17.8 0.0 0.0026 16.6 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.1 EMC99198.1 - 0.0015 18.2 0.1 0.02 14.6 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMC99198.1 - 0.0077 15.1 0.0 0.32 9.8 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EMC99198.1 - 0.0096 14.8 0.0 0.69 8.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC99198.1 - 0.03 14.3 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMC99198.1 - 0.047 12.1 0.0 0.07 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EMC99198.1 - 0.074 12.9 0.0 0.26 11.1 0.0 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMC99198.1 - 0.17 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ILVD_EDD PF00920.16 EMC99199.1 - 4.1e-205 682.1 0.2 4.7e-205 681.9 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family F-box PF00646.28 EMC99200.1 - 0.00013 21.5 0.3 0.00031 20.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC99200.1 - 0.0031 17.2 0.3 0.0031 17.2 0.2 2.2 3 0 0 3 3 3 1 F-box-like Ribosomal_L37ae PF01780.14 EMC99200.1 - 0.039 13.8 0.2 0.082 12.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF4568 PF15132.1 EMC99200.1 - 0.042 13.0 0.4 0.075 12.2 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4568) GDPD PF03009.12 EMC99201.1 - 5.2e-37 127.7 0.0 6.8e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1400 PF07176.6 EMC99201.1 - 0.0072 16.2 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1400) Tubulin PF00091.20 EMC99202.1 - 6.1e-71 238.6 0.0 9.7e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC99202.1 - 6.7e-43 145.7 0.3 1.4e-42 144.6 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMC99202.1 - 3.9e-06 26.9 0.1 1.4e-05 25.0 0.0 2.0 2 1 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMC99202.1 - 0.048 13.1 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Nop16 PF09420.5 EMC99203.1 - 6.2e-45 153.2 8.3 8.4e-45 152.8 5.7 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Oxidored_FMN PF00724.15 EMC99204.1 - 2.6e-52 177.9 0.0 3.3e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1772 PF08592.6 EMC99205.1 - 1.9e-17 63.2 4.2 2.3e-17 63.0 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2040 PF09745.4 EMC99207.1 - 2e-37 127.8 20.9 2e-37 127.8 14.5 2.9 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) Patatin PF01734.17 EMC99209.1 - 1.9e-22 80.2 0.0 4.7e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.22 EMC99209.1 - 8.3e-05 22.9 0.0 0.00027 21.2 0.0 1.9 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EMC99209.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMC99209.1 - 0.0078 16.1 0.0 0.022 14.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC99209.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EMC99209.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMC99209.1 - 0.23 11.2 0.1 1 9.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EMC99209.1 - 0.55 10.5 0.0 1.2 9.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-B_box PF00643.19 EMC99209.1 - 2.7 7.9 15.4 0.099 12.5 2.5 3.0 2 0 0 2 2 2 0 B-box zinc finger Hexapep PF00132.19 EMC99210.1 - 1.1e-17 62.5 6.3 4.5e-10 38.5 2.5 3.6 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMC99210.1 - 3.2e-14 52.1 5.6 7.8e-10 38.1 1.3 3.3 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Ferrochelatase PF00762.14 EMC99211.1 - 5.6e-90 301.5 0.0 6.5e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 EMC99212.1 - 5.1e-41 140.2 0.0 9e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EMC99212.1 - 3.2e-30 105.2 0.0 4.3e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EMC99212.1 - 1.1e-11 45.1 0.0 2.4e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 EMC99212.1 - 0.013 15.6 0.1 0.027 14.5 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain YL1 PF05764.8 EMC99213.1 - 7.6e-26 91.1 30.8 7.6e-26 91.1 21.3 1.6 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EMC99213.1 - 5.2e-06 25.9 0.1 1.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Acetate_kinase PF00871.12 EMC99214.1 - 1.5e-100 336.5 0.0 1.8e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family SNARE PF05739.14 EMC99215.1 - 4.8e-19 67.8 2.4 4.8e-19 67.8 1.7 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EMC99215.1 - 1e-11 44.8 0.3 1e-11 44.8 0.2 2.3 2 1 0 2 2 2 1 Syntaxin DNA_repr_REX1B PF14966.1 EMC99215.1 - 0.0075 16.6 0.2 0.02 15.2 0.2 1.8 1 0 0 1 1 1 1 DNA repair REX1-B SlyX PF04102.7 EMC99215.1 - 0.072 13.4 6.8 0.53 10.6 0.2 2.8 2 1 0 2 2 2 0 SlyX PBP1_TM PF14812.1 EMC99215.1 - 0.089 13.1 1.2 0.2 12.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3772 PF12607.3 EMC99215.1 - 1.7 8.3 4.9 9.7 5.9 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) EF-hand_1 PF00036.27 EMC99216.1 - 3.4e-41 135.3 12.8 1.1e-09 36.8 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC99216.1 - 2e-36 123.9 5.8 7e-20 70.9 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC99216.1 - 8.3e-35 118.1 12.3 7.4e-16 57.5 0.5 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMC99216.1 - 1.4e-30 102.3 8.0 1.3e-09 37.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC99216.1 - 6.2e-26 88.5 9.7 1.5e-06 27.2 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMC99216.1 - 1.5e-15 56.8 0.3 2.4e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMC99216.1 - 3.3e-09 36.4 3.8 0.0007 19.3 0.2 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC99216.1 - 1.2e-08 34.9 0.1 0.0042 17.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EMC99216.1 - 3.6e-08 32.9 0.5 0.024 14.2 0.0 3.5 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EMC99216.1 - 5.6e-07 29.4 2.2 4.9e-06 26.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EMC99216.1 - 0.00016 21.4 0.5 0.33 10.6 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EMC99216.1 - 0.00027 20.5 0.2 0.077 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 EMC99216.1 - 0.0027 17.6 0.7 1.4 8.9 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EMC99216.1 - 0.0027 17.2 0.1 0.14 11.6 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 EMC99216.1 - 0.0091 16.3 1.7 2.1 8.6 0.0 2.5 1 1 1 2 2 2 1 Toprim-like DUF3349 PF11829.3 EMC99216.1 - 0.017 15.4 0.4 9 6.7 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) YqeY PF09424.5 EMC99216.1 - 0.11 12.3 0.7 0.56 10.0 0.2 2.0 1 1 1 2 2 2 0 Yqey-like protein RloB PF13707.1 EMC99216.1 - 0.19 11.3 3.7 1.2 8.6 1.5 2.3 1 1 0 1 1 1 0 RloB-like protein EF-hand_10 PF14788.1 EMC99216.1 - 0.37 10.4 3.9 0.91 9.2 0.1 3.2 1 1 3 4 4 4 0 EF hand PB1 PF00564.19 EMC99216.1 - 0.45 10.2 2.5 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain DUF3650 PF12368.3 EMC99216.1 - 1.1 8.8 3.2 4.1 6.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) PPO1_DWL PF12142.3 EMC99217.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Abhydrolase_1 PF00561.15 EMC99218.1 - 3.4e-44 151.1 0.1 3e-23 82.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC99218.1 - 8.7e-14 51.9 0.1 3.8e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EMC99218.1 - 0.00043 19.0 0.0 0.00059 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EMC99218.1 - 0.0015 18.2 0.0 0.022 14.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EMC99218.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Peptidase_M14 PF00246.19 EMC99219.1 - 1.1e-67 228.5 0.0 1.4e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosomal_L7Ae PF01248.21 EMC99220.1 - 9.3e-20 69.9 0.4 6.3e-14 51.2 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family polyprenyl_synt PF00348.12 EMC99221.1 - 2.3e-56 190.5 0.0 2.6e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Cortexin PF11057.3 EMC99221.1 - 0.074 12.6 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Cortexin of kidney Ank_2 PF12796.2 EMC99226.1 - 6.5e-35 119.3 4.1 6.5e-05 23.1 0.5 10.8 6 6 2 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EMC99226.1 - 5e-18 63.9 23.1 0.87 9.5 0.0 15.8 17 1 1 18 18 18 5 Ankyrin repeat Ank_3 PF13606.1 EMC99226.1 - 2e-16 58.4 11.5 3.7 8.0 0.0 15.4 17 1 1 18 18 18 3 Ankyrin repeat Ank_4 PF13637.1 EMC99226.1 - 4.7e-16 58.8 15.9 0.23 12.0 0.0 12.4 12 2 2 14 14 14 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC99226.1 - 4.5e-09 36.2 19.5 0.037 14.3 0.0 10.7 12 1 1 13 13 13 3 Ankyrin repeats (many copies) Alpha_kinase PF02816.13 EMC99227.1 - 4.4e-45 153.6 0.0 9.2e-45 152.6 0.0 1.6 2 0 0 2 2 2 1 Alpha-kinase family VWA_2 PF13519.1 EMC99227.1 - 3.6e-06 27.1 0.0 7.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMC99227.1 - 3.2e-05 23.7 0.1 9.4e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Amidohydro_2 PF04909.9 EMC99228.1 - 1.4e-20 73.9 0.2 1.7e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Complex1_LYR PF05347.10 EMC99230.1 - 9.1e-15 54.2 0.2 1e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMC99230.1 - 6.2e-11 42.3 0.3 7.1e-11 42.1 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like BRCT PF00533.21 EMC99231.1 - 0.0046 17.0 0.0 0.35 11.0 0.0 2.7 2 1 1 3 3 3 2 BRCA1 C Terminus (BRCT) domain STE2 PF02116.10 EMC99232.1 - 9.1e-52 175.8 15.3 1.1e-51 175.5 10.6 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF1754 PF08555.5 EMC99233.1 - 2.1e-15 57.0 13.7 2.1e-15 57.0 9.5 1.3 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) PTPA PF03095.10 EMC99233.1 - 0.072 12.2 0.3 0.086 11.9 0.2 1.0 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein G-gamma PF00631.17 EMC99233.1 - 1.2 8.9 3.4 0.74 9.6 0.4 1.9 2 0 0 2 2 2 0 GGL domain CAF-1_p150 PF11600.3 EMC99233.1 - 1.5 8.1 20.2 1.9 7.7 14.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 EMC99233.1 - 1.7 8.3 11.3 2.2 8.0 7.8 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1682 PF07946.9 EMC99233.1 - 2.6 6.8 11.8 3.2 6.5 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HhH-GPD PF00730.20 EMC99234.1 - 4.1e-20 72.0 0.0 8.9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMC99234.1 - 1.7e-08 33.7 0.0 4.4e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif UEV PF05743.8 EMC99236.1 - 1.2e-34 118.6 0.0 1.9e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EMC99236.1 - 1.5e-12 46.9 0.5 2.7e-12 46.0 0.1 1.7 2 0 0 2 2 2 1 Vps23 core domain CENP-Q PF13094.1 EMC99236.1 - 0.0046 16.9 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit FliD_N PF02465.13 EMC99236.1 - 6.9 7.1 8.7 1.3 9.4 1.5 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus G-alpha PF00503.15 EMC99237.1 - 3.1e-132 440.9 1.0 3.7e-132 440.7 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC99237.1 - 2.1e-15 56.3 1.7 9.6e-11 41.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EMC99237.1 - 0.00019 20.9 0.0 0.00086 18.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EMC99237.1 - 0.0015 18.9 0.5 3.1 8.3 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EMC99237.1 - 0.0056 15.8 3.6 0.21 10.6 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EMC99237.1 - 0.0072 15.8 0.1 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain MCM PF00493.18 EMC99237.1 - 0.019 13.7 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family GTP_EFTU PF00009.22 EMC99237.1 - 0.034 13.5 0.2 2.1 7.7 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EMC99237.1 - 0.089 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EMC99237.1 - 0.092 12.7 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mog1 PF04603.7 EMC99237.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Ran-interacting Mog1 protein LIM PF00412.17 EMC99241.1 - 7.9e-22 77.0 23.1 1.2e-12 47.6 2.9 2.8 3 0 0 3 3 3 2 LIM domain WRC PF08879.5 EMC99241.1 - 0.007 16.0 0.1 2.3 7.9 0.1 2.6 2 0 0 2 2 2 2 WRC Ribosomal_L18p PF00861.17 EMC99242.1 - 7.2e-44 148.8 2.4 8.5e-44 148.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EMC99242.1 - 2.5e-32 111.3 10.8 2.5e-32 111.3 7.5 2.3 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EMC99242.1 - 0.043 13.8 1.7 0.44 10.5 0.0 3.0 4 0 0 4 4 4 0 Threonine synthase N terminus DUF2365 PF10157.4 EMC99243.1 - 0.11 12.3 0.3 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) MFS_1 PF07690.11 EMC99244.1 - 1.2e-31 109.7 30.9 1.2e-31 109.7 21.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 EMC99245.1 - 3.4e-48 164.5 0.1 4e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_3 PF07859.8 EMC99246.1 - 2.9e-29 102.1 0.2 4e-29 101.7 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMC99246.1 - 2.4e-22 79.1 0.0 3.1e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EMC99246.1 - 2.1e-08 34.0 0.5 3.4e-08 33.3 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC99246.1 - 4e-05 23.6 0.8 7.4e-05 22.7 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC99246.1 - 0.00081 18.6 0.2 0.0063 15.7 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family F-box-like PF12937.2 EMC99247.1 - 4.2e-07 29.5 1.2 2.2e-06 27.2 0.9 2.4 1 1 0 1 1 1 1 F-box-like Corona_NS4 PF03905.8 EMC99248.1 - 0.31 10.8 1.5 0.42 10.4 0.3 1.7 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 NIF PF03031.13 EMC99249.1 - 3.7e-52 176.1 0.1 4.6e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase FAD_binding_2 PF00890.19 EMC99250.1 - 5.7e-46 157.1 0.5 8e-45 153.4 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC99250.1 - 5.9e-07 28.7 0.9 6e-06 25.4 0.6 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMC99250.1 - 7.3e-05 21.4 0.5 0.053 11.9 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMC99250.1 - 0.00014 21.8 0.0 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC99250.1 - 0.00085 18.5 0.3 0.0062 15.6 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMC99250.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EMC99250.1 - 0.0083 16.5 0.4 3.2 8.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EMC99250.1 - 0.0084 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EMC99250.1 - 0.019 15.0 0.0 0.077 13.0 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CBM_21 PF03370.8 EMC99251.1 - 1.2e-34 118.6 0.2 2.1e-34 117.8 0.2 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit BolA PF01722.13 EMC99253.1 - 7.9e-18 64.1 0.0 9.6e-18 63.9 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Metallophos PF00149.23 EMC99254.1 - 2.7e-10 39.9 0.1 1.1e-09 37.9 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC99254.1 - 3.7e-06 26.8 0.0 5.3e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PI3Ka PF00613.15 EMC99255.1 - 4.5e-55 185.6 0.3 7e-55 185.0 0.2 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EMC99255.1 - 3.4e-44 151.0 0.0 4e-43 147.5 0.0 2.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EMC99255.1 - 3.2e-28 98.3 0.0 7.2e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 EMC99256.1 - 6.6e-34 115.8 0.0 1.4e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EMC99256.1 - 1.9e-17 62.8 0.0 5.4e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF2525 PF10733.4 EMC99256.1 - 0.073 12.9 2.1 0.078 12.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) adh_short_C2 PF13561.1 EMC99257.1 - 5.3e-24 85.3 0.0 6.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC99257.1 - 2.6e-22 79.5 1.8 3.5e-22 79.0 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC99257.1 - 1e-05 25.2 0.4 1.5e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC99257.1 - 0.00077 18.9 0.1 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DLH PF01738.13 EMC99258.1 - 3.7e-22 78.6 0.1 4.3e-22 78.4 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC99258.1 - 0.00023 20.9 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EMC99259.1 - 4.9e-30 104.4 31.2 6.8e-30 103.9 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EMC99259.1 - 0.0004 20.7 0.6 0.0034 17.7 0.2 2.5 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fungal_trans PF04082.13 EMC99260.1 - 2.7e-15 55.9 0.0 4.2e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC99260.1 - 5.4e-07 29.4 9.8 1.1e-06 28.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Longin PF13774.1 EMC99260.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain TFIIE_alpha PF02002.12 EMC99261.1 - 4.6e-15 55.0 0.6 1.2e-13 50.4 0.1 2.8 2 1 0 2 2 2 1 TFIIE alpha subunit zf-FPG_IleRS PF06827.9 EMC99261.1 - 0.0036 16.9 1.4 0.023 14.3 0.1 2.4 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS zf-IS66 PF13005.2 EMC99261.1 - 0.0053 16.7 1.7 0.76 9.7 0.2 2.8 2 0 0 2 2 2 1 zinc-finger binding domain of transposase IS66 zf-TFIIB PF13453.1 EMC99261.1 - 0.011 14.8 3.0 0.45 9.7 0.1 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger DZR PF12773.2 EMC99261.1 - 0.026 14.3 1.3 0.078 12.8 0.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon Rrf2 PF02082.15 EMC99261.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator zf-ribbon_3 PF13248.1 EMC99261.1 - 0.19 10.9 1.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin PF00301.15 EMC99261.1 - 0.25 11.2 2.3 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Rubredoxin zf-NADH-PPase PF09297.6 EMC99261.1 - 0.29 10.6 0.1 0.29 10.6 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain TF_Zn_Ribbon PF08271.7 EMC99261.1 - 0.47 9.8 3.1 1 8.7 0.3 2.5 3 0 0 3 3 3 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.7 EMC99261.1 - 5.1 6.9 5.3 8.7 6.2 0.6 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.1 EMC99261.1 - 5.8 6.5 7.2 1e+02 2.5 5.1 2.3 1 1 1 2 2 2 0 zinc-ribbon domain PseudoU_synth_1 PF01416.15 EMC99262.1 - 1.7e-20 73.3 0.0 7.6e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase MgtE_N PF03448.12 EMC99262.1 - 0.026 14.8 0.1 0.077 13.3 0.1 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain Glyco_transf_90 PF05686.7 EMC99263.1 - 2.8e-27 95.4 0.0 3.6e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 adh_short PF00106.20 EMC99264.1 - 2.9e-11 43.5 0.0 3.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMC99264.1 - 5.3e-07 29.8 0.0 6.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMC99264.1 - 2.3e-06 27.3 0.1 3.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMC99264.1 - 3.1e-05 23.3 2.6 5e-05 22.6 1.8 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMC99264.1 - 0.00069 19.1 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EMC99264.1 - 0.004 17.5 0.3 0.007 16.7 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EMC99264.1 - 0.016 14.9 0.8 0.033 13.9 0.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EMC99264.1 - 0.052 12.5 1.3 0.11 11.4 0.9 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase OGFr_N PF04664.8 EMC99265.1 - 1.2e-18 67.2 0.0 1.5e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region CFEM PF05730.6 EMC99266.1 - 2.6e-06 27.1 5.8 5.3e-06 26.1 4.0 1.4 1 0 0 1 1 1 1 CFEM domain DUF3431 PF11913.3 EMC99267.1 - 1.2e-16 60.8 0.0 1.6e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4396 PF14342.1 EMC99268.1 - 0.061 13.4 0.2 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) NADH-u_ox-rdase PF10785.4 EMC99268.1 - 0.25 11.5 1.0 4 7.7 0.0 2.5 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Sugar_tr PF00083.19 EMC99269.1 - 1.4e-37 129.4 23.2 2e-37 128.8 16.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC99269.1 - 3.7e-14 52.2 29.6 6.2e-14 51.4 20.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1993 PF09351.5 EMC99270.1 - 5.8e-43 146.6 0.0 6.7e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) TMV_coat PF00721.16 EMC99270.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Virus coat protein (TMV like) Sugar_tr PF00083.19 EMC99271.1 - 2.9e-93 312.9 32.2 3.4e-93 312.6 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC99271.1 - 1.3e-20 73.4 44.7 9.4e-20 70.6 30.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF973 PF06157.6 EMC99271.1 - 0.02 13.8 6.7 0.041 12.8 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DHDPS PF00701.17 EMC99272.1 - 2.7e-40 137.8 0.0 3.4e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.3 EMC99273.1 - 1.3e-19 70.1 0.1 1.7e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MIS13 PF08202.6 EMC99274.1 - 1.7e-43 148.8 0.0 2.7e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family AMP-binding PF00501.23 EMC99275.1 - 1e-43 149.3 0.0 1.4e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Urb2 PF10441.4 EMC99276.1 - 7.6e-34 117.2 0.3 1.8e-33 116.0 0.2 1.6 1 0 0 1 1 1 1 Urb2/Npa2 family DUF543 PF04418.7 EMC99277.1 - 5.6e-27 93.5 0.0 6.3e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Glyco_hydro_67M PF07488.7 EMC99278.1 - 2.9e-147 489.8 0.3 4e-147 489.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EMC99278.1 - 2.7e-88 295.1 1.1 4.8e-88 294.3 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EMC99278.1 - 3.4e-27 94.8 0.0 6.3e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus BetaGal_dom4_5 PF13364.1 EMC99278.1 - 0.0059 16.8 3.3 0.01 16.0 0.6 2.7 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Glyco_hydro_20b PF02838.10 EMC99278.1 - 0.05 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 HK PF02110.10 EMC99279.1 - 9.8e-77 257.4 0.8 1.5e-76 256.7 0.6 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EMC99279.1 - 3.9e-58 195.5 7.2 9.6e-58 194.2 3.7 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EMC99279.1 - 8.7e-05 21.8 0.0 0.00025 20.3 0.0 1.8 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 EMC99279.1 - 0.0018 17.5 0.1 0.0043 16.3 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate kinase Pinin_SDK_memA PF04696.8 EMC99280.1 - 2.6e-14 52.9 13.5 2.6e-14 52.9 9.4 1.4 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region TrwC PF08751.6 EMC99280.1 - 0.093 12.1 3.1 0.15 11.4 2.1 1.3 1 0 0 1 1 1 0 TrwC relaxase Phage_Gp19 PF09355.5 EMC99280.1 - 1.2 8.9 3.8 0.31 10.8 0.3 1.7 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 DNA_pol_lambd_f PF10391.4 EMC99281.1 - 9.6e-21 73.0 0.6 2.6e-20 71.6 0.4 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EMC99281.1 - 1.5e-18 66.1 0.1 3.1e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EMC99281.1 - 5.5e-17 61.8 0.0 1.6e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EMC99281.1 - 1.1e-08 35.1 0.0 2.8e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EMC99281.1 - 0.0022 18.1 0.1 8.1 6.7 0.0 3.5 3 0 0 3 3 3 2 Helix-hairpin-helix domain MMR_HSR1 PF01926.18 EMC99282.1 - 2.5e-12 46.7 0.0 4.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC99282.1 - 7.5e-05 21.9 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EMC99282.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.8 EMC99282.1 - 0.0049 15.7 0.1 0.0081 15.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EMC99282.1 - 0.082 12.7 0.6 0.73 9.6 0.1 2.3 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 EMC99282.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Zn_clus PF00172.13 EMC99283.1 - 3.8e-07 29.8 11.8 8.1e-07 28.8 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.3 EMC99284.1 - 1.8e-26 93.1 0.1 1.9e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) LINES_C PF14695.1 EMC99284.1 - 0.17 11.1 0.0 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 Lines C-terminus GrpB PF04229.9 EMC99286.1 - 2.8e-38 131.2 0.0 2.7e-37 128.0 0.0 1.9 1 1 0 1 1 1 1 GrpB protein Zn_clus PF00172.13 EMC99287.1 - 1.3e-08 34.5 8.8 2.4e-08 33.7 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMC99288.1 - 2.7e-16 59.9 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC99288.1 - 1.4e-06 28.1 0.1 4.4e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EMC99288.1 - 9.9e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC99288.1 - 0.007 16.3 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMC99288.1 - 0.022 13.7 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Acetyltransf_1 PF00583.19 EMC99289.1 - 2.9e-05 23.9 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC99289.1 - 3.2e-05 23.9 0.3 5.3e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC99289.1 - 0.00025 21.1 0.1 0.00055 20.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC99289.1 - 0.12 12.2 0.0 2.4 8.0 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Copper-fist PF00649.13 EMC99290.1 - 1.4e-06 27.3 7.7 1.4e-06 27.3 5.3 2.4 3 0 0 3 3 3 1 Copper fist DNA binding domain Viral_P18 PF04521.8 EMC99290.1 - 0.001 18.5 0.2 0.0021 17.5 0.1 1.5 1 0 0 1 1 1 1 ssRNA positive strand viral 18kD cysteine rich protein Methyltransf_16 PF10294.4 EMC99291.1 - 9.6e-18 64.2 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMC99291.1 - 0.00044 20.7 0.0 0.00077 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC99291.1 - 0.00048 19.8 0.0 0.00099 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC99291.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.12 EMC99291.1 - 0.022 13.7 0.0 0.073 12.0 0.0 1.7 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family GidB PF02527.10 EMC99291.1 - 0.056 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.9 EMC99291.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EMC99291.1 - 0.17 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) KTI12 PF08433.5 EMC99292.1 - 5.7e-81 271.6 0.0 6.4e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EMC99292.1 - 0.00023 21.9 0.0 0.00036 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC99292.1 - 0.00068 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC99292.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF566 PF04484.7 EMC99293.1 - 2.8 7.3 7.2 3.1 7.2 5.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3320 PF11784.3 EMC99295.1 - 0.045 13.2 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) SNF2_N PF00176.18 EMC99296.1 - 6.8e-71 238.4 0.4 1e-70 237.8 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC99296.1 - 3.7e-11 42.7 0.0 8.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EMC99296.1 - 1.6e-09 37.3 1.7 3e-09 36.4 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC99296.1 - 7.4e-07 29.0 2.7 2e-06 27.6 1.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EMC99296.1 - 1e-06 28.3 0.0 3.3e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EMC99296.1 - 4.5e-05 23.0 3.1 0.00011 21.8 2.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC99296.1 - 8.5e-05 22.3 2.5 0.00021 21.0 1.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC99296.1 - 0.0021 17.6 5.2 0.013 15.0 3.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Nop14 PF04147.7 EMC99296.1 - 0.0058 14.6 14.8 0.0087 14.0 10.2 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EMC99296.1 - 0.13 11.5 17.4 0.28 10.4 12.1 1.6 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 EMC99296.1 - 0.21 11.1 13.7 0.47 10.0 9.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EMC99296.1 - 0.36 8.7 14.1 0.56 8.1 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EMC99296.1 - 1.5 7.1 15.4 2.2 6.6 10.7 1.1 1 0 0 1 1 1 0 Daxx Family zf-C3HC4_4 PF15227.1 EMC99296.1 - 7 6.6 11.4 7.4 6.5 5.6 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING CN_hydrolase PF00795.17 EMC99298.1 - 2.1e-32 111.9 0.0 3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.20 EMC99299.1 - 1.6e-16 60.6 0.1 2.3e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99299.1 - 3.6e-10 40.0 0.0 4.3e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC99299.1 - 0.098 12.0 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Thg1C PF14413.1 EMC99302.1 - 2e-50 169.4 0.1 2.7e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EMC99302.1 - 3.3e-44 149.7 0.0 5e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Pro-kuma_activ PF09286.6 EMC99303.1 - 1.4e-48 164.6 0.1 8e-48 162.1 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain UDPGP PF01704.13 EMC99304.1 - 2e-53 181.4 0.0 2.7e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EMC99304.1 - 0.028 14.4 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF4188 PF13826.1 EMC99306.1 - 2.9e-23 82.1 0.4 4.3e-23 81.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) RRP7 PF12923.2 EMC99307.1 - 5.4e-32 110.5 5.7 8.3e-32 109.9 4.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EMC99307.1 - 0.00039 19.9 0.0 0.049 13.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC99307.1 - 0.0014 18.5 0.0 0.44 10.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.18 EMC99309.1 - 2.6e-67 226.7 0.4 4.2e-67 226.0 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC99309.1 - 1.4e-13 50.4 0.0 3.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC99309.1 - 8.9e-08 32.1 1.1 2.2e-07 30.9 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Spore_III_AB PF09548.5 EMC99309.1 - 0.43 10.3 3.1 28 4.3 0.0 2.7 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) NDUF_B8 PF05821.6 EMC99310.1 - 1e-07 31.8 0.2 1.4e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DYW_deaminase PF14432.1 EMC99312.1 - 3.8e-10 39.7 0.0 7.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases AlgF PF11182.3 EMC99312.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Alginate O-acetyl transferase AlgF Clr2 PF10383.4 EMC99314.1 - 2.3e-10 40.6 0.0 1.9e-09 37.6 0.0 2.4 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 HATPase_c PF02518.21 EMC99316.1 - 7.4e-28 96.4 0.0 2.7e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMC99316.1 - 8.4e-26 90.1 0.0 1.4e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMC99316.1 - 1.2e-13 50.8 0.0 3.3e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EMC99316.1 - 6.8 6.9 19.9 1.1 9.4 0.0 4.1 5 0 0 5 5 5 0 HAMP domain BBE PF08031.7 EMC99317.1 - 1.6e-07 31.1 0.6 3.1e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 Berberine and berberine like Aminotran_5 PF00266.14 EMC99319.1 - 2e-61 207.8 0.0 2.5e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMC99319.1 - 0.00028 19.3 0.1 0.00063 18.1 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme ATX_III PF08098.6 EMC99319.1 - 0.073 12.9 0.1 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 Anemonia sulcata toxin III family DegT_DnrJ_EryC1 PF01041.12 EMC99319.1 - 0.079 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Hydrolase_6 PF13344.1 EMC99320.1 - 7.6e-24 83.5 0.0 1.4e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC99320.1 - 3.1e-12 46.0 0.0 2e-11 43.4 0.0 2.4 4 0 0 4 4 4 1 HAD-hyrolase-like HAD_2 PF13419.1 EMC99320.1 - 0.0097 16.1 0.0 2.8 8.1 0.0 2.7 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC99320.1 - 0.098 13.0 0.0 1.7 8.9 0.0 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Chorion_S16 PF05836.7 EMC99321.1 - 0.045 13.6 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Chorion protein S16 Pkinase PF00069.20 EMC99322.1 - 1.7e-52 178.1 0.0 2.4e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99322.1 - 4e-19 68.7 0.0 1.5e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMC99322.1 - 8e-05 22.4 0.2 0.00028 20.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC99322.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EMC99322.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MMR_HSR1_C PF08438.5 EMC99324.1 - 9.8e-31 106.2 0.0 3e-30 104.6 0.0 1.7 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EMC99324.1 - 3.5e-18 65.6 0.0 7.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC99324.1 - 2.6e-10 39.7 0.2 8.5e-08 31.6 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EMC99324.1 - 0.0032 17.3 0.6 0.063 13.0 0.1 2.7 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 EMC99324.1 - 0.0057 16.1 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EMC99324.1 - 0.028 14.3 0.2 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EMC99324.1 - 0.029 13.9 0.2 6.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 EMC99324.1 - 0.047 12.9 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 EMC99324.1 - 0.068 13.1 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EMC99324.1 - 0.074 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AIG1 PF04548.11 EMC99324.1 - 0.13 11.3 0.1 0.26 10.3 0.1 1.5 1 0 0 1 1 1 0 AIG1 family UPF1_Zn_bind PF09416.5 EMC99325.1 - 2.3e-73 244.8 1.7 5.9e-73 243.4 1.1 1.8 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 EMC99325.1 - 6.9e-58 196.0 1.2 1.1e-57 195.3 0.8 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EMC99325.1 - 8.1e-56 188.5 0.0 1.4e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC99325.1 - 1.9e-13 49.9 0.0 8.4e-13 47.8 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EMC99325.1 - 4.5e-12 45.9 0.1 5.8e-11 42.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EMC99325.1 - 2.4e-07 30.7 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EMC99325.1 - 0.00064 19.3 0.8 1.2 8.5 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EMC99325.1 - 0.0014 17.6 0.8 0.0069 15.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EMC99325.1 - 0.0016 18.1 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EMC99325.1 - 0.0018 17.6 0.1 0.026 13.8 0.0 2.5 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EMC99325.1 - 0.01 15.3 0.1 0.025 14.0 0.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase KaiC PF06745.8 EMC99325.1 - 0.036 13.1 0.0 0.66 9.0 0.0 2.3 2 0 0 2 2 2 0 KaiC PIF1 PF05970.9 EMC99325.1 - 0.046 12.6 0.1 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_16 PF13191.1 EMC99325.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EMC99325.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 EMC99325.1 - 0.15 12.1 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EMC99325.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Brix PF04427.13 EMC99326.1 - 2.2e-47 161.1 0.1 2.8e-47 160.8 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF1771 PF08590.5 EMC99329.1 - 5e-17 61.6 11.7 5e-17 61.6 8.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EMC99329.1 - 2.1e-16 59.8 0.4 4.8e-16 58.7 0.2 1.7 1 0 0 1 1 1 1 Smr domain SUN PF03856.8 EMC99330.1 - 9.5e-86 287.1 23.4 2e-85 286.0 16.2 1.5 1 1 0 1 1 1 1 Beta-glucosidase (SUN family) Med3 PF11593.3 EMC99330.1 - 2.4 7.3 12.1 3.6 6.7 8.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PP1c_bdg PF10488.4 EMC99331.1 - 0.13 11.4 3.5 0.26 10.4 0.5 1.9 1 1 1 2 2 2 0 Phosphatase-1 catalytic subunit binding region Actin PF00022.14 EMC99332.1 - 7.2e-117 390.1 0.0 8.9e-117 389.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMC99332.1 - 0.034 12.7 0.0 0.18 10.3 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Band_7 PF01145.20 EMC99333.1 - 1.4e-25 90.2 4.3 1.7e-25 89.9 2.7 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 EMC99333.1 - 0.0031 16.4 2.1 0.004 16.0 1.4 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.13 EMC99333.1 - 0.014 15.1 0.3 0.023 14.4 0.2 1.3 1 0 0 1 1 1 0 GatB domain Prenylcys_lyase PF07156.9 EMC99333.1 - 0.087 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase Maf1 PF09174.5 EMC99335.1 - 3.6e-53 180.0 0.0 4.4e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.5 EMC99335.1 - 0.093 12.7 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Clat_adaptor_s PF01217.15 EMC99337.1 - 5.8e-52 175.1 1.1 7e-52 174.9 0.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.16 EMC99338.1 - 2e-13 49.8 0.0 2.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Yeast_MT PF11403.3 EMC99339.1 - 2.7 8.2 4.9 3.1 8.0 2.1 2.1 1 1 1 2 2 2 0 Yeast metallothionein Pcc1 PF09341.5 EMC99340.1 - 4.3e-23 81.1 2.1 4.8e-22 77.7 1.4 2.0 1 1 0 1 1 1 1 Transcription factor Pcc1 Asp PF00026.18 EMC99342.1 - 6.3e-57 193.2 3.1 8.6e-57 192.7 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC99342.1 - 2.7e-06 27.4 0.0 4e-05 23.6 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMC99342.1 - 6.3e-06 26.6 0.2 0.29 11.6 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease IDO PF01231.13 EMC99343.1 - 2.7e-164 546.6 0.0 3.1e-164 546.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EMC99343.1 - 0.076 11.5 0.0 1.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) DSBA PF01323.15 EMC99345.1 - 6.9e-11 42.0 0.0 7.2e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Aminotran_5 PF00266.14 EMC99347.1 - 7.5e-94 314.4 0.0 9.4e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMC99347.1 - 2.6e-06 26.8 0.0 3.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMC99347.1 - 0.0027 16.7 0.0 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C4 PF00105.13 EMC99347.1 - 0.011 15.9 0.8 0.04 14.1 0.6 1.9 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Use1 PF09753.4 EMC99349.1 - 3.4e-06 26.6 17.3 1.9e-05 24.2 11.9 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 Nucleoplasmin PF03066.10 EMC99349.1 - 0.006 16.0 3.2 0.011 15.2 2.2 1.4 1 0 0 1 1 1 1 Nucleoplasmin GldM_N PF12081.3 EMC99349.1 - 0.15 11.6 2.6 0.47 9.9 0.2 2.3 2 0 0 2 2 2 0 GldM N-terminal domain Sporozoite_P67 PF05642.6 EMC99349.1 - 0.18 9.5 3.9 0.23 9.2 2.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 EMC99349.1 - 0.35 10.6 6.4 0.93 9.2 4.4 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Bacillus_HBL PF05791.6 EMC99349.1 - 0.77 9.1 7.2 0.9 8.8 0.3 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Sec2p PF06428.6 EMC99349.1 - 1 9.2 9.1 0.31 10.9 2.2 2.6 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p GP41 PF00517.12 EMC99349.1 - 1.1 8.7 4.5 2.3 7.6 3.1 1.5 1 0 0 1 1 1 0 Retroviral envelope protein NOA36 PF06524.7 EMC99349.1 - 1.2 8.3 4.2 1.7 7.7 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein DivIC PF04977.10 EMC99349.1 - 5.7 6.5 11.5 0.62 9.5 3.8 2.4 2 0 0 2 2 2 0 Septum formation initiator Coatomer_E PF04733.9 EMC99350.1 - 2.6e-46 158.1 0.7 2.9e-46 157.9 0.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EMC99350.1 - 0.0079 16.5 8.3 0.63 10.4 0.4 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat Halo_GVPC PF05465.8 EMC99350.1 - 1.7 8.6 5.8 0.35 10.8 1.1 2.2 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat RNase_H PF00075.19 EMC99351.1 - 1.6e-13 51.0 0.0 3.1e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 EMC99351.1 - 1.1e-05 25.1 0.2 0.0022 17.7 0.0 3.0 3 0 0 3 3 3 1 Reverse transcriptase-like DUF3115 PF11312.3 EMC99352.1 - 9.6e-90 300.6 0.0 1.2e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) FAD_binding_3 PF01494.14 EMC99353.1 - 1.2e-15 57.3 2.0 1.1e-09 37.8 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMC99353.1 - 2.1e-10 40.0 0.2 8.4e-05 21.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMC99353.1 - 1.6e-09 37.9 0.0 4.7e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC99353.1 - 1.1e-08 34.4 0.1 3e-08 32.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMC99353.1 - 1.4e-08 33.6 0.3 0.00014 20.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EMC99353.1 - 6.5e-06 26.3 0.1 2.8e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC99353.1 - 1.2e-05 24.3 0.3 0.00037 19.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EMC99353.1 - 5e-05 23.2 0.1 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMC99353.1 - 8.1e-05 21.8 1.2 0.00019 20.6 0.2 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMC99353.1 - 0.00062 18.9 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMC99353.1 - 0.0012 19.2 0.3 0.076 13.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC99353.1 - 0.0014 17.6 0.4 0.12 11.2 0.1 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EMC99353.1 - 0.01 15.4 0.0 0.089 12.3 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 EMC99353.1 - 0.042 12.9 0.3 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EMC99353.1 - 0.083 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMC99353.1 - 0.1 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_9 PF13454.1 EMC99353.1 - 0.11 12.3 0.1 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EMC99353.1 - 0.16 11.6 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus p450 PF00067.17 EMC99354.1 - 8.1e-56 189.4 0.0 1.2e-55 188.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.1 EMC99354.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Stirrup NmrA PF05368.8 EMC99356.1 - 1.3e-33 116.1 0.0 1.8e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC99356.1 - 2.4e-12 47.2 0.1 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMC99356.1 - 6e-06 26.2 0.4 1.2e-05 25.3 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC99356.1 - 3.3e-05 23.6 0.1 5.9e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC99356.1 - 0.00017 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC99356.1 - 0.00018 20.3 0.1 0.00029 19.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMC99356.1 - 0.0029 16.5 0.0 0.99 8.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein DapB_N PF01113.15 EMC99356.1 - 0.0035 17.2 0.1 0.0075 16.1 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMC99356.1 - 0.096 12.9 0.1 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 EMC99357.1 - 2.3e-13 49.5 2.2 4.8e-13 48.4 1.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC99357.1 - 9e-08 31.9 7.3 1.5e-07 31.2 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FliX PF10768.4 EMC99358.1 - 0.42 10.8 3.4 0.7 10.1 2.4 1.4 1 0 0 1 1 1 0 Class II flagellar assembly regulator PI-PLC-X PF00388.14 EMC99359.1 - 3.6e-62 208.0 0.0 9.1e-62 206.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMC99359.1 - 2.3e-33 114.6 0.0 4.7e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMC99359.1 - 0.015 15.2 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF1010 PF06231.6 EMC99360.1 - 0.26 11.2 2.2 0.36 10.8 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1010) DUF3704 PF12488.3 EMC99361.1 - 0.12 12.0 2.4 0.88 9.2 1.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3704) Amidase PF01425.16 EMC99362.1 - 2.4e-32 112.3 6.6 1.1e-31 110.2 4.6 1.8 1 1 0 1 1 1 1 Amidase adh_short PF00106.20 EMC99363.1 - 1.3e-15 57.7 0.1 1.7e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99363.1 - 2.6e-09 37.2 0.0 3.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC99363.1 - 0.00033 20.1 0.1 0.00041 19.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMC99363.1 - 0.0075 15.9 0.6 0.086 12.4 0.4 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 EMC99363.1 - 0.044 13.6 0.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 EMC99363.1 - 0.061 12.2 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMC99363.1 - 0.068 13.1 0.1 0.094 12.7 0.1 1.4 1 1 0 1 1 1 0 NADH(P)-binding Zn_clus PF00172.13 EMC99364.1 - 2.2e-07 30.6 7.9 3.7e-07 29.9 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EMC99366.1 - 2.2e-59 200.7 0.0 4e-59 199.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99366.1 - 4.4e-27 94.7 0.0 6.7e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC99366.1 - 0.13 12.0 0.1 0.46 10.1 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 EMC99367.1 - 2.4e-94 316.4 15.5 5.3e-51 173.6 1.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC99367.1 - 3.6e-27 94.9 46.0 1.7e-19 69.7 15.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC99367.1 - 0.0019 16.6 36.6 0.0089 14.4 2.2 3.6 2 2 2 4 4 4 3 MFS/sugar transport protein Paramyxo_ncap PF00973.14 EMC99368.1 - 0.064 11.9 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Glyco_hydro_72 PF03198.9 EMC99372.1 - 1.6e-128 428.1 4.8 2e-128 427.8 3.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EMC99372.1 - 0.00058 18.8 0.0 0.00096 18.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain LRR_4 PF12799.2 EMC99373.1 - 0.0053 16.3 0.0 1.2 8.8 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC99373.1 - 0.2 11.4 0.6 19 5.1 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 EMC99373.1 - 0.28 11.3 5.8 1.9e+02 2.6 0.0 5.9 7 0 0 7 7 7 0 Leucine Rich repeat Transketolase_N PF00456.16 EMC99375.1 - 6.7e-148 491.9 0.1 9.1e-148 491.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMC99375.1 - 2.2e-45 154.3 0.1 3.7e-45 153.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMC99375.1 - 1.1e-12 48.0 0.0 2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EMC99375.1 - 1.1e-05 24.5 0.0 9.7e-05 21.4 0.0 2.1 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EMC99375.1 - 0.0069 15.1 0.1 0.013 14.2 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component COesterase PF00135.23 EMC99376.1 - 2.4e-49 168.4 0.0 3.8e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC99376.1 - 0.0053 16.3 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMC99377.1 - 2.5e-11 43.0 0.1 3.2e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Caleosin PF05042.8 EMC99378.1 - 2.3e-54 183.5 0.0 2.8e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.27 EMC99378.1 - 0.00014 20.8 0.5 0.033 13.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMC99378.1 - 0.00026 21.0 0.1 0.18 11.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC99378.1 - 0.0021 17.7 6.7 0.005 16.6 0.7 2.7 3 0 0 3 3 3 1 EF-hand domain Abhydrolase_3 PF07859.8 EMC99379.1 - 9e-40 136.5 0.0 1.2e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMC99379.1 - 6.1e-07 28.5 0.1 3.3e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMC99379.1 - 0.031 14.0 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family GTP_EFTU PF00009.22 EMC99380.1 - 4.8e-39 133.7 0.0 7.6e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EMC99380.1 - 4.1e-24 84.2 0.0 9.6e-24 83.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EMC99380.1 - 1.5e-16 60.0 0.0 1.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMC99380.1 - 2.4e-06 27.5 0.0 6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EMC99380.1 - 6.2e-06 25.7 0.1 0.0014 18.1 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EMC99380.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rossmann-like PF10727.4 EMC99380.1 - 0.12 12.0 2.5 0.14 11.8 0.4 2.1 2 0 0 2 2 2 0 Rossmann-like domain Vps5 PF09325.5 EMC99381.1 - 8.6e-15 54.6 5.5 2e-14 53.4 3.8 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EMC99381.1 - 4.7e-09 36.0 0.0 9.5e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 PX domain PAT1 PF09770.4 EMC99381.1 - 0.052 11.8 23.6 0.08 11.1 16.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ADH_N PF08240.7 EMC99382.1 - 1.1e-10 41.2 0.3 1.5e-09 37.6 0.2 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC99382.1 - 1.3e-07 31.2 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zip PF02535.17 EMC99383.1 - 9.9e-45 152.9 9.2 6.1e-44 150.2 6.4 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Hat1_N PF10394.4 EMC99384.1 - 7e-26 91.2 0.0 1.3e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus E1_dh PF00676.15 EMC99387.1 - 2.6e-115 384.2 0.3 3.4e-115 383.8 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EMC99387.1 - 0.00041 19.3 0.0 0.00061 18.8 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase BMC PF00936.14 EMC99387.1 - 0.15 11.7 2.0 0.19 11.4 0.0 2.2 3 0 0 3 3 3 0 BMC domain WD40 PF00400.27 EMC99388.1 - 2.3e-50 166.7 17.8 1.7e-09 37.1 0.5 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EMC99388.1 - 6.2e-11 41.8 0.8 1.1e-10 41.0 0.6 1.4 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EMC99388.1 - 2.5e-08 32.5 8.1 0.0015 16.7 0.3 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 EMC99388.1 - 6.5e-05 22.4 0.7 0.00012 21.6 0.5 1.5 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EMC99388.1 - 0.014 14.1 0.3 0.48 9.0 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.1 EMC99388.1 - 0.017 15.3 5.9 15 5.9 0.0 5.2 3 2 2 5 5 5 0 PQQ-like domain Mito_carr PF00153.22 EMC99389.1 - 3.3e-47 158.1 7.4 9.1e-17 60.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2428 PF10350.4 EMC99390.1 - 1.2e-55 188.2 3.3 1.7e-55 187.8 0.4 2.3 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EMC99390.1 - 6.4e-07 28.9 20.6 0.0067 16.4 0.1 8.7 8 0 0 8 8 8 3 HEAT repeat Tim17 PF02466.14 EMC99391.1 - 2.2e-27 95.6 4.0 2.8e-27 95.2 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PX PF00787.19 EMC99393.1 - 3.8e-17 62.1 0.0 9e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EMC99393.1 - 5e-09 35.7 9.3 0.00021 20.6 0.6 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF1675 PF07897.6 EMC99393.1 - 0.013 15.3 2.0 0.024 14.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) BAR PF03114.13 EMC99393.1 - 5.1 6.5 8.4 11 5.4 1.5 2.7 2 1 0 2 2 2 0 BAR domain HET PF06985.6 EMC99394.1 - 0.0083 16.2 4.2 0.099 12.7 0.6 2.4 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) D123 PF07065.9 EMC99394.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 D123 Serpin PF00079.15 EMC99395.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) TraT PF05818.7 EMC99395.1 - 2.2 7.6 10.9 0.4 10.0 4.6 1.9 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Piwi PF02171.12 EMC99396.1 - 1.5e-59 201.4 0.0 1.7e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Piwi domain DUF4535 PF15054.1 EMC99396.1 - 0.015 14.6 0.3 0.028 13.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) PAM2 PF07145.10 EMC99397.1 - 0.063 12.7 0.8 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region HDV_ag PF01517.13 EMC99399.1 - 0.0076 15.9 1.1 0.0076 15.9 0.8 1.6 2 0 0 2 2 2 1 Hepatitis delta virus delta antigen TPR_7 PF13176.1 EMC99399.1 - 0.24 11.3 1.2 0.69 9.8 0.8 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.1 EMC99399.1 - 0.25 11.6 3.1 0.33 11.2 1.7 1.7 1 1 0 1 1 1 0 Snapin/Pallidin Amidase PF01425.16 EMC99399.1 - 0.27 10.0 1.7 0.32 9.8 1.2 1.0 1 0 0 1 1 1 0 Amidase Peptidase_S46 PF10459.4 EMC99399.1 - 0.53 8.6 2.9 0.64 8.3 2.0 1.0 1 0 0 1 1 1 0 Peptidase S46 FUSC PF04632.7 EMC99399.1 - 1.5 7.1 7.4 1.6 7.0 5.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1325 PF07039.6 EMC99402.1 - 2.3e-21 75.7 0.0 4.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain PMI_typeI PF01238.16 EMC99403.1 - 5.5e-144 479.7 0.1 6.5e-144 479.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Glyco_hydro_39 PF01229.12 EMC99404.1 - 0.11 10.8 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 MFS_1 PF07690.11 EMC99405.1 - 4.9e-15 55.1 27.8 1e-11 44.1 14.0 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily Herpes_pp38 PF04846.8 EMC99405.1 - 0.041 13.2 6.0 0.034 13.4 1.6 2.6 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein Gly-zipper_YMGG PF13441.1 EMC99405.1 - 0.19 11.3 3.9 0.69 9.4 2.7 2.0 1 0 0 1 1 1 0 YMGG-like Gly-zipper Arf PF00025.16 EMC99407.1 - 3.5e-73 244.5 0.2 4.1e-73 244.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC99407.1 - 2.6e-13 49.4 2.2 5.6e-10 38.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EMC99407.1 - 7.6e-13 48.0 0.0 9.7e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMC99407.1 - 8.3e-13 48.0 0.0 9.2e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC99407.1 - 5.1e-11 42.1 0.0 5.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC99407.1 - 6.9e-08 33.0 0.0 1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC99407.1 - 0.0001 22.2 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMC99407.1 - 0.016 14.3 0.1 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF3986 PF13143.1 EMC99407.1 - 0.23 11.9 0.9 0.77 10.2 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Glyco_transf_8 PF01501.15 EMC99408.1 - 2e-20 73.2 0.0 2.8e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.22 EMC99409.1 - 3.5e-57 190.1 0.3 1.3e-18 66.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_35 PF01301.14 EMC99411.1 - 3.8e-51 174.3 0.1 5.3e-51 173.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EMC99411.1 - 1.4e-06 28.5 0.0 3.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Cellulase PF00150.13 EMC99411.1 - 0.0025 17.0 0.0 0.0053 15.9 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) P5CR_dimer PF14748.1 EMC99412.1 - 1.7e-31 108.3 1.4 4e-31 107.1 1.0 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMC99412.1 - 7.6e-11 42.2 6.7 3.1e-09 37.1 0.0 4.0 3 1 1 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent Methyltransf_18 PF12847.2 EMC99413.1 - 7.8e-07 29.6 0.0 1.6e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC99413.1 - 1.2e-06 28.3 0.0 6.4e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC99413.1 - 4.6e-05 23.0 0.0 0.00019 21.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC99413.1 - 7.7e-05 23.1 0.0 0.00012 22.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC99413.1 - 8.3e-05 22.6 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EMC99413.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EMC99413.1 - 0.00015 21.0 0.1 0.0003 20.0 0.1 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_12 PF08242.7 EMC99413.1 - 0.00055 20.3 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC99413.1 - 0.0016 18.7 0.0 0.0039 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC99413.1 - 0.0022 18.0 0.1 0.0037 17.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EMC99413.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_17 PF12692.2 EMC99413.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_4 PF02390.12 EMC99413.1 - 0.031 13.3 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EMC99413.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.11 EMC99414.1 - 1.8e-36 125.6 32.5 1.8e-36 125.6 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3197 PF11432.3 EMC99414.1 - 0.038 13.9 0.4 0.095 12.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) NfeD PF01957.13 EMC99414.1 - 0.51 10.4 3.6 4.6 7.3 0.6 2.9 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding MIP PF00230.15 EMC99415.1 - 2.9e-50 170.8 13.5 3.5e-50 170.5 9.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF374 PF04028.8 EMC99416.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF374) MFS_1 PF07690.11 EMC99417.1 - 3e-09 36.0 12.3 3.4e-09 35.9 8.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC99417.1 - 1.6e-07 30.2 7.8 1.9e-07 30.0 5.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter ExoD PF06055.7 EMC99417.1 - 0.0059 15.7 1.1 0.0067 15.5 0.8 1.1 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD Lig_chan PF00060.21 EMC99417.1 - 0.044 13.5 0.3 0.054 13.2 0.2 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel Amidase PF01425.16 EMC99418.1 - 4e-91 306.0 0.0 4.8e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 Amidase LicD PF04991.8 EMC99420.1 - 8.5e-36 123.9 3.2 8.9e-35 120.6 2.2 2.0 1 1 0 1 1 1 1 LicD family HET PF06985.6 EMC99423.1 - 1.1e-15 58.0 0.3 1.4e-15 57.7 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RasGAP_C PF03836.10 EMC99424.1 - 1.7e-41 141.2 0.4 1.4e-40 138.2 0.1 2.5 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 EMC99424.1 - 2.1e-30 105.8 0.0 9.8e-29 100.4 0.0 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EMC99424.1 - 3.4e-09 36.7 0.0 1.3e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 EMC99424.1 - 2e-05 23.8 57.3 1.4 8.7 0.9 15.3 16 0 0 16 16 16 5 IQ calmodulin-binding motif DUF4200 PF13863.1 EMC99424.1 - 5.4 6.9 19.6 0.61 10.0 1.7 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) Zn_clus PF00172.13 EMC99426.1 - 4.2e-08 32.9 10.6 7.7e-08 32.1 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC99426.1 - 0.00016 20.6 0.0 0.00032 19.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thiolase_C PF02803.13 EMC99428.1 - 8.9e-11 41.2 0.4 7.9e-10 38.2 0.1 2.6 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EMC99428.1 - 2.5e-08 33.4 0.1 2.7e-06 26.9 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EMC99428.1 - 1.9e-06 27.0 0.4 2.9e-05 23.2 0.0 2.5 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EMC99428.1 - 9.6e-06 25.2 0.0 2.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMC99428.1 - 0.0035 17.1 0.1 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 EMC99428.1 - 0.04 12.3 0.2 0.093 11.1 0.1 1.5 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) TMV_coat PF00721.16 EMC99429.1 - 0.13 12.2 0.0 1.7 8.5 0.0 2.0 2 0 0 2 2 2 0 Virus coat protein (TMV like) RNB PF00773.14 EMC99430.1 - 2.3e-61 207.8 0.0 4.1e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 RNB domain Abhydrolase_3 PF07859.8 EMC99431.1 - 1e-21 77.5 0.1 6e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC99431.1 - 1.2e-10 40.9 0.0 0.00025 20.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC99431.1 - 1.7e-07 31.0 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMC99431.1 - 9.7e-05 21.3 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 EMC99431.1 - 0.00015 20.3 0.0 0.04 12.4 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EMC99431.1 - 0.0002 20.8 0.0 0.001 18.5 0.0 2.3 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.23 EMC99431.1 - 0.0034 16.1 0.1 0.013 14.2 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.4 EMC99431.1 - 0.01 15.0 0.0 0.47 9.6 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2048 PF09752.4 EMC99431.1 - 0.095 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) ThiS PF02597.15 EMC99432.1 - 3e-08 33.9 0.0 6.5e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 ThiS family Glyco_transf_28 PF03033.15 EMC99433.1 - 9.1e-19 67.5 0.0 6.6e-18 64.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMC99433.1 - 3.6e-08 32.3 0.0 6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.15 EMC99433.1 - 1.8e-05 23.8 0.1 4.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif ATG_C PF09333.6 EMC99433.1 - 0.0058 16.7 0.0 0.028 14.5 0.0 2.2 1 0 0 1 1 1 1 ATG C terminal domain 2_5_RNA_ligase2 PF13563.1 EMC99434.1 - 0.05 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily GXWXG PF14231.1 EMC99434.1 - 0.1 12.2 0.1 0.22 11.1 0.0 1.6 1 1 0 1 1 1 0 GXWXG protein DZF PF07528.9 EMC99435.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 DZF domain p450 PF00067.17 EMC99437.1 - 2.2e-59 201.2 0.0 2.7e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TUDOR PF00567.19 EMC99439.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EMC99439.1 - 0.0018 17.4 2.2 0.0018 17.4 1.6 2.5 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) DUF1325 PF07039.6 EMC99439.1 - 0.0025 17.4 0.3 0.0025 17.4 0.2 1.7 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.1 EMC99439.1 - 0.004 16.9 0.1 0.0082 15.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.5 EMC99439.1 - 0.028 14.0 0.2 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor-knot PF11717.3 EMC99439.1 - 0.074 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Med3 PF11593.3 EMC99439.1 - 0.33 10.1 6.9 0.41 9.8 4.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAP1 PF08601.5 EMC99441.1 - 7.8e-37 127.7 41.2 7.8e-37 127.7 28.5 3.0 2 2 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EMC99441.1 - 1.1e-09 38.1 9.4 1.9e-09 37.3 6.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC99441.1 - 0.023 14.5 11.4 0.11 12.2 7.6 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 EMC99441.1 - 0.16 12.2 10.0 0.45 10.8 6.9 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Herpes_UL6 PF01763.11 EMC99441.1 - 0.2 9.7 1.3 0.31 9.1 0.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like IncA PF04156.9 EMC99441.1 - 7.5 6.0 10.0 2.4 7.7 3.1 2.1 2 0 0 2 2 2 0 IncA protein Myb_DNA-bind_2 PF08914.6 EMC99442.1 - 8.3e-17 60.7 0.1 1.6e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EMC99442.1 - 1.5e-05 25.5 0.0 2.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Rap1, DNA-binding BRCT PF00533.21 EMC99442.1 - 0.012 15.7 0.0 0.073 13.2 0.0 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain zf-DHHC PF01529.15 EMC99443.1 - 1.1e-33 116.0 0.3 1.1e-33 116.0 0.2 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EMC99443.1 - 0.071 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily RNase_T PF00929.19 EMC99445.1 - 0.018 15.3 0.3 6.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Exonuclease adh_short_C2 PF13561.1 EMC99446.1 - 4.7e-23 82.1 0.3 5.7e-23 81.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC99446.1 - 3.6e-21 75.8 6.2 4.5e-21 75.4 4.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC99446.1 - 2.5e-12 46.8 3.5 3.9e-12 46.2 2.5 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC99446.1 - 4.5e-05 22.9 0.2 8.5e-05 22.1 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC99446.1 - 0.0019 17.1 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1860 PF08949.5 EMC99446.1 - 0.0061 16.1 0.5 0.0061 16.1 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1860) NAD_binding_10 PF13460.1 EMC99446.1 - 0.014 15.4 1.7 0.025 14.5 1.2 1.6 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EMC99446.1 - 0.023 13.3 0.2 0.032 12.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ELFV_dehydrog PF00208.16 EMC99446.1 - 0.042 13.4 0.1 0.067 12.7 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HECT PF00632.20 EMC99447.1 - 1e-59 202.2 0.0 1.7e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DEAD PF00270.24 EMC99448.1 - 1.7e-39 135.0 0.0 3.2e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC99448.1 - 2.7e-24 84.7 0.0 8.5e-24 83.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC99448.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMC99448.1 - 0.024 14.7 0.2 0.086 12.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain F-box PF00646.28 EMC99450.1 - 0.0065 16.0 2.9 0.019 14.5 2.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC99450.1 - 0.02 14.5 3.3 0.02 14.5 2.3 1.8 2 0 0 2 2 2 0 F-box-like Gp37_Gp68 PF07505.6 EMC99450.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 Bacillus_HBL PF05791.6 EMC99452.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) FlpD PF02662.11 EMC99452.1 - 0.051 13.2 0.5 0.068 12.8 0.4 1.1 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit LAMTOR PF15454.1 EMC99454.1 - 7.5e-13 48.5 1.6 1e-12 48.1 0.2 1.9 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator HSP70 PF00012.15 EMC99456.1 - 1.4e-266 885.2 11.7 1.6e-266 885.0 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC99456.1 - 4.1e-20 71.6 0.6 4.1e-19 68.3 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EMC99456.1 - 0.0038 16.0 0.3 0.083 11.7 0.1 2.3 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 EMC99456.1 - 0.053 12.4 1.5 0.12 11.2 0.1 2.3 2 1 0 2 2 2 0 StbA protein Hydantoinase_A PF01968.13 EMC99456.1 - 0.58 9.2 6.7 0.13 11.3 0.1 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EMC99456.1 - 6.1 6.6 8.5 6.8 6.5 1.2 3.7 2 2 0 2 2 2 0 Cell division protein FtsA adh_short PF00106.20 EMC99459.1 - 3.6e-32 111.5 0.7 5e-32 111.1 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99459.1 - 1.3e-28 100.4 0.1 1.6e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99459.1 - 2.6e-14 53.2 0.3 4.2e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC99459.1 - 0.00021 20.8 0.7 0.00062 19.2 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC99459.1 - 0.00032 19.5 0.4 0.00042 19.1 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.10 EMC99459.1 - 0.034 13.7 0.1 0.075 12.6 0.0 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Asp PF00026.18 EMC99460.1 - 6.9e-38 130.6 0.1 8.8e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EMC99460.1 - 1.1e-06 28.9 0.3 0.00055 20.3 0.0 3.6 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 EMC99460.1 - 0.00062 19.5 0.4 0.01 15.6 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 EMC99460.1 - 0.011 15.3 0.1 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal RVP PF00077.15 EMC99460.1 - 0.063 13.2 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease adh_short PF00106.20 EMC99461.1 - 4.2e-27 95.0 0.2 6e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99461.1 - 2.7e-22 79.7 0.0 3.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99461.1 - 9.3e-07 28.6 0.2 1.6e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC99461.1 - 6.2e-05 22.5 0.1 0.00032 20.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMC99461.1 - 0.0042 16.8 0.5 0.015 15.0 0.2 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_1 PF00175.16 EMC99462.1 - 7.8e-14 52.1 0.0 1.3e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EMC99462.1 - 7.5e-11 42.3 0.2 2e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 EMC99462.1 - 9.5e-08 32.0 0.2 1.8e-05 24.7 0.0 3.0 2 1 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EMC99462.1 - 1.4e-06 28.2 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 EMC99462.1 - 0.0026 17.4 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 Protoglobin SIS PF01380.17 EMC99462.1 - 0.042 13.4 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 SIS domain Malic_M PF03949.10 EMC99463.1 - 3e-83 279.2 0.1 4e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMC99463.1 - 1.7e-67 226.5 0.0 2.8e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 EMC99463.1 - 0.046 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 6PGD PF00393.14 EMC99464.1 - 3.5e-68 229.9 0.0 5.2e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EMC99464.1 - 6.3e-25 87.9 0.0 1.3e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EMC99464.1 - 0.0089 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Defensin_1 PF00323.14 EMC99464.1 - 0.086 13.2 0.9 0.23 11.8 0.4 1.8 2 0 0 2 2 2 0 Mammalian defensin Pex2_Pex12 PF04757.9 EMC99465.1 - 1.4e-38 132.5 2.2 2e-38 132.0 1.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EMC99465.1 - 0.0012 18.6 4.4 0.0025 17.6 3.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC99465.1 - 0.043 13.5 0.2 0.043 13.5 0.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMC99465.1 - 0.32 11.0 9.0 0.12 12.4 3.2 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EMC99466.1 - 1.8 8.1 12.5 7 6.3 8.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Abhydrolase_3 PF07859.8 EMC99467.1 - 1.7e-51 174.8 0.0 2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC99467.1 - 0.001 18.8 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EMC99467.1 - 0.018 13.6 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EMC99467.1 - 0.063 12.4 0.6 1 8.5 0.2 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family IBN_N PF03810.14 EMC99470.1 - 3.1e-10 39.8 0.1 2e-09 37.2 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMC99470.1 - 0.0012 18.7 4.4 0.0017 18.2 0.1 3.3 4 0 0 4 4 4 1 Exportin 1-like protein F-box-like_2 PF13013.1 EMC99471.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain tRNA-synt_2d PF01409.15 EMC99472.1 - 1e-81 273.7 0.0 1.6e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EMC99472.1 - 2.5e-06 26.5 2.2 0.00026 19.9 0.0 3.4 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EMC99472.1 - 0.00077 19.0 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EMC99472.1 - 0.037 13.0 0.1 0.091 11.7 0.1 1.6 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Rio2_N PF09202.6 EMC99472.1 - 0.056 13.5 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Rio2, N-terminal ADH_N PF08240.7 EMC99473.1 - 2.8e-23 81.7 4.7 4.4e-23 81.1 3.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC99473.1 - 1.2e-17 63.6 0.0 1.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC99473.1 - 6.7e-09 36.7 0.0 1.2e-08 35.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMC99473.1 - 0.0023 17.1 0.1 0.0038 16.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMC99473.1 - 0.0087 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3431 PF11913.3 EMC99475.1 - 5.6e-78 261.4 0.0 7.3e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) VWA_2 PF13519.1 EMC99476.1 - 0.00011 22.4 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMC99476.1 - 0.00025 20.8 0.0 0.00074 19.2 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans_2 PF11951.3 EMC99477.1 - 6.3e-13 48.0 0.1 6.7e-13 47.9 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain CM1 PF03026.10 EMC99477.1 - 0.061 12.4 0.1 0.085 11.9 0.1 1.1 1 0 0 1 1 1 0 Influenza C virus M1 protein F-box PF00646.28 EMC99478.1 - 0.0022 17.5 0.1 0.0054 16.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC99478.1 - 0.012 15.3 0.3 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 F-box-like CTP_transf_2 PF01467.21 EMC99480.1 - 1e-27 97.1 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Glyco_hydro_10 PF00331.15 EMC99481.1 - 5e-93 311.6 0.5 5.8e-93 311.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Bac_rhamnosid PF05592.6 EMC99481.1 - 0.044 12.0 0.1 4.6 5.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase Esterase_phd PF10503.4 EMC99482.1 - 3.9e-24 85.1 0.5 5.3e-24 84.6 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMC99482.1 - 1.6e-09 37.2 1.3 2.3e-09 36.8 0.9 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC99482.1 - 5.3e-05 23.0 0.2 7e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC99482.1 - 0.00029 20.7 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC99482.1 - 0.00042 19.9 0.1 0.00056 19.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMC99482.1 - 0.0026 17.2 1.1 0.0043 16.5 0.8 1.4 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.23 EMC99482.1 - 0.0074 15.0 2.1 0.011 14.4 0.2 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC99482.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMC99482.1 - 0.094 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Img2 PF05046.9 EMC99484.1 - 0.058 13.6 0.0 0.091 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Glyoxalase PF00903.20 EMC99485.1 - 2.8e-40 137.2 0.2 3.8e-19 68.9 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMC99485.1 - 2.4e-32 111.7 0.0 1.6e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMC99485.1 - 3.2e-16 59.3 0.1 8.2e-07 29.0 0.0 4.0 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMC99485.1 - 4.8e-08 33.0 0.0 0.027 14.3 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain PRT_C PF08372.5 EMC99485.1 - 0.008 15.6 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal MoaF PF10703.4 EMC99485.1 - 0.07 12.1 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F DUF605 PF04652.11 EMC99488.1 - 6.5 6.0 16.9 9.1 5.5 11.7 1.2 1 0 0 1 1 1 0 Vta1 like Cu-oxidase_3 PF07732.10 EMC99490.1 - 1.1e-40 138.0 1.5 1.1e-40 138.0 1.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EMC99490.1 - 3.4e-38 131.0 0.8 8.2e-38 129.7 0.6 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC99490.1 - 1.7e-35 121.5 7.6 1.9e-31 108.4 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase DUF723 PF05265.8 EMC99490.1 - 0.086 12.6 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF723) Cupin_5 PF06172.6 EMC99491.1 - 8e-23 80.8 0.0 9.5e-21 74.1 0.0 2.1 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Copper-fist PF00649.13 EMC99492.1 - 6.6e-18 63.6 1.4 6.6e-18 63.6 1.0 2.6 1 1 1 2 2 2 1 Copper fist DNA binding domain Glyco_hydro_cc PF11790.3 EMC99493.1 - 1.7e-59 201.1 0.1 1.9e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_18 PF00704.23 EMC99495.1 - 7e-17 61.8 0.0 1.5e-15 57.4 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 UBA PF00627.26 EMC99495.1 - 1.8e-06 27.5 0.0 5.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain MBOAT_2 PF13813.1 EMC99496.1 - 1.5e-09 37.7 6.2 3.1e-09 36.7 4.3 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Aldose_epim PF01263.15 EMC99497.1 - 7.5e-41 140.1 0.0 9.4e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.3 EMC99498.1 - 8.3e-104 347.5 1.5 1.2e-103 347.0 1.0 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.4 EMC99499.1 - 1.3e-112 376.9 0.0 1.6e-112 376.6 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn ADH_zinc_N PF00107.21 EMC99500.1 - 7.7e-26 90.1 1.6 1.2e-25 89.4 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC99500.1 - 1.5e-19 69.7 0.4 5e-19 68.0 0.3 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMC99500.1 - 8.8e-05 23.4 0.0 0.00021 22.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMC99500.1 - 0.0066 16.0 1.5 0.013 15.1 1.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EMC99500.1 - 0.068 13.1 1.2 0.13 12.2 0.9 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EMC99500.1 - 0.091 12.1 0.3 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMC99500.1 - 0.1 12.5 2.0 0.23 11.3 1.4 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Abhydrolase_3 PF07859.8 EMC99501.1 - 7.8e-16 58.2 0.1 3.4e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold TFIIA PF03153.8 EMC99502.1 - 1.9 8.3 18.7 2.3 8.0 12.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRF1 PF10380.4 EMC99502.1 - 2.4 8.5 7.9 1.5 9.1 0.2 2.5 1 1 1 2 2 2 0 Transcription factor CRF1 Pantoate_transf PF02548.10 EMC99503.1 - 7.5e-106 353.0 1.1 8.8e-106 352.7 0.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EMC99503.1 - 4.6e-09 35.8 0.3 4.6e-09 35.8 0.2 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PA PF02225.17 EMC99503.1 - 0.36 10.5 3.1 4.3 7.1 0.1 3.1 2 1 1 3 3 3 0 PA domain APG12 PF04110.8 EMC99504.1 - 7.4e-28 96.5 0.0 9.9e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EMC99504.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Dfp1_Him1_M PF08630.5 EMC99505.1 - 1.1e-39 135.0 0.3 2.8e-39 133.7 0.0 1.8 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EMC99505.1 - 2.7e-22 78.1 1.6 4.3e-22 77.5 1.1 1.3 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EMC99505.1 - 0.0031 17.3 0.0 0.0076 16.0 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Peptidase_C14 PF00656.17 EMC99506.1 - 3.4e-44 151.4 0.0 4.7e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EMC99506.1 - 0.2 11.4 2.5 1.6 8.5 1.7 2.4 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Atx10homo_assoc PF09759.4 EMC99507.1 - 5.9e-23 80.5 0.0 1.3e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Beta-lactamase PF00144.19 EMC99508.1 - 6.7e-37 127.2 0.1 9.8e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Inositol_P PF00459.20 EMC99509.1 - 3.5e-54 183.9 0.4 7e-54 182.9 0.3 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family LUC7 PF03194.10 EMC99510.1 - 4.8e-68 229.4 0.5 6e-68 229.1 0.3 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DASH_Duo1 PF08651.5 EMC99510.1 - 0.051 13.1 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Rabaptin PF03528.10 EMC99510.1 - 2.7 7.9 5.8 1.2 9.0 0.4 2.2 1 1 0 2 2 2 0 Rabaptin Gpi16 PF04113.9 EMC99511.1 - 5.9e-202 671.6 0.0 7.5e-202 671.3 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Cyt-b5 PF00173.23 EMC99512.1 - 1.1e-21 76.3 0.1 1.5e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MGC-24 PF05283.6 EMC99512.1 - 0.041 13.6 0.2 0.058 13.1 0.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) VHS PF00790.14 EMC99513.1 - 4.3e-32 110.6 0.2 6.9e-32 110.0 0.1 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EMC99513.1 - 4.8e-16 57.8 0.0 9.1e-16 56.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC99513.1 - 8.9e-15 54.0 0.1 1.6e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC99513.1 - 7.2e-13 47.8 0.0 1.5e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EMC99513.1 - 0.004 16.5 1.7 0.012 15.1 1.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif GAT PF03127.9 EMC99513.1 - 0.034 14.1 0.5 0.2 11.6 0.0 2.4 3 0 0 3 3 3 0 GAT domain Pkinase PF00069.20 EMC99514.1 - 3.5e-71 239.3 0.0 5.8e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99514.1 - 8.1e-46 156.1 0.0 1.4e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMC99514.1 - 8e-21 74.2 0.1 2.8e-20 72.4 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EMC99514.1 - 1.7e-06 27.2 0.0 2.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC99514.1 - 0.018 14.8 0.1 0.43 10.2 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Med13_C PF06333.7 EMC99515.1 - 1.6e-55 188.4 0.0 2.6e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal NUC153 PF08159.7 EMC99516.1 - 2.5e-12 46.1 3.6 5.6e-12 45.0 2.5 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EMC99516.1 - 5.6e-05 22.8 1.3 0.046 13.6 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat MARVEL PF01284.18 EMC99518.1 - 0.035 13.9 13.9 0.24 11.1 5.9 2.1 1 1 1 2 2 2 0 Membrane-associating domain WD40 PF00400.27 EMC99519.1 - 2.4e-22 77.9 7.3 2.8e-09 36.4 0.4 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 EMC99519.1 - 4.3e-07 29.8 0.0 0.00086 19.0 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.1 EMC99519.1 - 4.3e-05 23.2 3.3 0.0001 22.0 2.3 1.7 1 0 0 1 1 1 1 Ring finger domain Nup160 PF11715.3 EMC99519.1 - 0.0087 14.2 0.3 0.54 8.3 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 zf-rbx1 PF12678.2 EMC99519.1 - 0.0097 15.9 0.2 0.023 14.7 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC99519.1 - 0.23 11.5 3.2 0.77 9.8 2.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) XLF PF09302.6 EMC99520.1 - 4.7e-29 101.3 0.0 7.2e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) IDEAL PF08858.5 EMC99520.1 - 0.33 10.4 5.5 0.66 9.5 0.3 2.7 2 0 0 2 2 2 0 IDEAL domain CactinC_cactus PF09732.4 EMC99521.1 - 7.3e-54 180.6 1.6 1.1e-53 180.1 1.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EMC99521.1 - 1.9e-53 180.6 0.9 2.7e-53 180.0 0.6 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin DUF1087 PF06465.8 EMC99521.1 - 0.032 14.1 0.2 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Fork_head PF00250.13 EMC99522.1 - 9e-17 60.9 0.8 1.3e-16 60.3 0.0 1.6 2 0 0 2 2 2 1 Fork head domain ER_lumen_recept PF00810.13 EMC99523.1 - 3.4e-34 118.4 8.0 4.8e-34 117.9 5.6 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EMC99523.1 - 0.023 14.2 0.0 0.023 14.2 0.0 3.2 3 1 1 4 4 4 0 PQ loop repeat MFS_1 PF07690.11 EMC99524.1 - 1.8e-32 112.4 24.6 1.8e-32 112.4 17.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC99524.1 - 3.1e-15 55.7 8.3 3.1e-15 55.7 5.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMC99524.1 - 1.4e-05 23.4 4.0 2.5e-05 22.7 2.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldedh PF00171.17 EMC99525.1 - 2.1e-10 39.5 0.0 9.9e-05 20.8 0.0 3.0 2 1 0 2 2 2 2 Aldehyde dehydrogenase family FAA_hydrolase PF01557.13 EMC99527.1 - 1.5e-46 158.5 0.0 2.2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMC99527.1 - 2.6e-15 56.3 0.0 6e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Cupin_2 PF07883.6 EMC99528.1 - 1.2e-11 43.9 0.0 2.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EMC99528.1 - 0.0052 16.2 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMC99528.1 - 0.0068 15.7 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) zf-C2H2 PF00096.21 EMC99529.1 - 3.5e-10 39.6 12.8 1.1e-05 25.5 0.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 EMC99529.1 - 4.1e-09 35.6 0.1 1.1e-08 34.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EMC99529.1 - 2e-07 30.9 7.3 1.1e-06 28.5 1.0 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC99529.1 - 1.2e-06 28.4 15.6 0.00047 20.3 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 EMC99529.1 - 3.6e-06 26.7 14.9 7.2e-06 25.8 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 EMC99529.1 - 0.15 12.3 3.0 5.7 7.3 1.3 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC99529.1 - 0.18 11.9 3.5 25 5.1 1.5 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Peptidase_S15 PF02129.13 EMC99530.1 - 1.6e-45 155.6 1.2 2.4e-45 155.0 0.8 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMC99530.1 - 5.5e-40 137.5 1.2 8.9e-40 136.8 0.9 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 EMC99530.1 - 1.5e-06 28.0 0.1 1e-05 25.3 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC99530.1 - 1.7e-06 28.1 0.2 4e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC99530.1 - 0.0067 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase IN_DBD_C PF00552.16 EMC99530.1 - 0.082 12.3 0.5 0.25 10.7 0.1 2.0 2 0 0 2 2 2 0 Integrase DNA binding domain FAD_binding_3 PF01494.14 EMC99531.1 - 1.1e-20 74.0 1.7 5.7e-20 71.6 0.6 2.4 2 1 0 2 2 2 1 FAD binding domain ADC PF06314.6 EMC99531.1 - 1.2e-13 50.9 0.0 3.1e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.1 EMC99531.1 - 3.5e-08 33.3 0.2 8.9e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC99531.1 - 1.5e-06 27.4 3.3 1.2e-05 24.3 0.5 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC99531.1 - 1.7e-05 23.8 0.7 3.7e-05 22.7 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC99531.1 - 7.6e-05 22.6 1.2 0.00038 20.4 0.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC99531.1 - 0.00047 19.1 2.4 0.002 17.1 1.0 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EMC99531.1 - 0.00068 18.6 0.7 0.0011 17.8 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EMC99531.1 - 0.0016 17.1 0.2 0.032 12.8 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EMC99531.1 - 0.0022 17.5 0.1 0.0059 16.1 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EMC99531.1 - 0.0046 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EMC99531.1 - 0.0047 17.0 0.5 0.014 15.4 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC99531.1 - 0.0054 17.1 0.3 0.013 15.8 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC99531.1 - 0.0079 14.7 1.6 0.022 13.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EMC99531.1 - 0.0084 15.2 0.0 0.96 8.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EMC99531.1 - 0.013 14.6 2.8 0.028 13.5 1.9 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EMC99531.1 - 0.083 12.3 0.2 0.17 11.2 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EMC99531.1 - 0.11 12.2 1.4 0.79 9.4 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EMC99531.1 - 0.25 10.9 0.5 0.86 9.2 0.4 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LigB PF02900.13 EMC99532.1 - 4.2e-21 75.1 0.0 5e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Ribosomal_S19e PF01090.14 EMC99534.1 - 9.2e-57 190.3 0.3 1.1e-56 190.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GPI-anchored PF10342.4 EMC99535.1 - 1.6e-20 73.3 1.3 2.8e-20 72.5 0.9 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cellulase PF00150.13 EMC99538.1 - 5.9e-12 45.3 1.6 2.8e-11 43.1 0.1 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EMC99538.1 - 0.021 13.9 0.0 0.077 12.1 0.0 1.9 1 1 0 1 1 1 0 Beta-galactosidase DUF4434 PF14488.1 EMC99538.1 - 0.05 13.3 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Aldo_ket_red PF00248.16 EMC99539.1 - 7.3e-45 152.9 0.0 1e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2744 PF10910.3 EMC99539.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2744) Antimicrobial18 PF08130.6 EMC99539.1 - 0.041 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Type A lantibiotic family eRF1_1 PF03463.10 EMC99540.1 - 2.2e-48 163.1 0.0 3.7e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EMC99540.1 - 4.6e-22 78.7 0.0 7.3e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMC99540.1 - 2.5e-21 76.0 0.0 4.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Ribonuc_L-PSP PF01042.16 EMC99542.1 - 4e-40 136.3 0.0 4.5e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ILVD_EDD PF00920.16 EMC99543.1 - 9.5e-202 671.0 2.6 1.1e-201 670.8 1.8 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 EMC99543.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Radical_SAM PF04055.16 EMC99544.1 - 0.0006 20.0 0.0 0.00095 19.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EMC99544.1 - 0.0057 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Abhydrolase_6 PF12697.2 EMC99545.1 - 1.8e-29 103.2 0.7 2.2e-29 102.9 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC99545.1 - 1.4e-12 47.5 0.0 3.3e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC99545.1 - 0.002 17.7 0.0 0.092 12.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMC99545.1 - 0.0032 17.2 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2462 PF09495.5 EMC99546.1 - 2.8e-16 60.0 15.5 2.8e-16 60.0 10.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) Kinesin PF00225.18 EMC99546.1 - 0.087 11.5 1.1 0.1 11.2 0.8 1.1 1 0 0 1 1 1 0 Kinesin motor domain DUF4636 PF15468.1 EMC99546.1 - 0.39 10.1 2.3 0.46 9.8 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) FMN_dh PF01070.13 EMC99551.1 - 2.2e-118 395.2 0.0 2.7e-118 394.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMC99551.1 - 1.1e-06 27.8 0.4 6e-06 25.3 0.1 2.0 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMC99551.1 - 2.2e-06 26.8 0.2 8.1e-06 24.9 0.0 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EMC99551.1 - 0.00036 19.8 0.1 0.0015 17.8 0.0 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EMC99551.1 - 0.00093 18.4 0.8 0.0015 17.7 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EMC99551.1 - 0.043 12.8 0.3 3.3 6.6 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG AP2 PF00847.15 EMC99552.1 - 1.1 9.4 4.3 49 4.1 1.5 3.0 3 0 0 3 3 3 0 AP2 domain TENA_THI-4 PF03070.11 EMC99553.1 - 0.00032 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family zf-BED PF02892.10 EMC99553.1 - 0.0065 16.2 0.5 0.014 15.1 0.4 1.5 1 0 0 1 1 1 1 BED zinc finger Noelin-1 PF12308.3 EMC99553.1 - 0.078 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein Transp_cyt_pur PF02133.10 EMC99554.1 - 1.6e-20 73.0 40.7 3.1e-20 72.1 28.2 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin F-box-like PF12937.2 EMC99555.1 - 6.6e-08 32.1 0.2 1.3e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC99555.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain YrhC PF14143.1 EMC99556.1 - 5.4 7.0 7.2 5.8 6.9 0.1 2.9 3 0 0 3 3 3 0 YrhC-like protein Tyrosinase PF00264.15 EMC99557.1 - 1.1e-31 110.7 0.0 1.7e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.14 EMC99559.1 - 4.4e-13 49.0 0.0 7.9e-13 48.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMC99559.1 - 6.1e-05 22.9 0.0 0.00019 21.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMC99559.1 - 0.00074 18.2 0.3 0.15 10.6 0.1 2.4 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.19 EMC99559.1 - 0.0011 17.9 0.1 0.0026 16.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC99559.1 - 0.0019 18.5 1.3 1.3 9.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC99559.1 - 0.0026 17.5 0.0 0.015 15.1 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC99559.1 - 0.049 13.4 2.4 0.22 11.3 1.5 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC99559.1 - 0.17 10.6 0.4 0.26 10.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain MARVEL PF01284.18 EMC99562.1 - 0.012 15.4 13.6 0.046 13.5 9.3 1.8 1 1 1 2 2 2 0 Membrane-associating domain Oxidored_FMN PF00724.15 EMC99563.1 - 1.7e-70 237.7 0.0 2e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EMC99563.1 - 0.083 11.7 0.0 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF1275 PF06912.6 EMC99565.1 - 2.6e-41 141.1 13.9 3.6e-41 140.6 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF998 PF06197.8 EMC99565.1 - 0.23 10.7 14.7 0.79 9.0 4.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF998) NfeD PF01957.13 EMC99565.1 - 0.51 10.4 3.5 6.2 6.9 0.0 3.0 1 1 3 4 4 4 0 NfeD-like C-terminal, partner-binding GTP_EFTU PF00009.22 EMC99566.1 - 5.3e-45 153.1 0.0 1.5e-44 151.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMC99566.1 - 1.5e-20 73.2 0.0 3.3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EMC99566.1 - 6.8e-05 22.8 0.0 0.00018 21.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EMC99566.1 - 0.00096 19.2 0.1 0.0023 17.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 G-alpha PF00503.15 EMC99566.1 - 0.0022 16.7 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Glyco_hydro_3_C PF01915.17 EMC99566.1 - 0.088 12.3 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Ran-binding PF05508.6 EMC99567.1 - 7.7e-109 363.2 0.0 1e-108 362.8 0.0 1.2 1 0 0 1 1 1 1 RanGTP-binding protein CorA PF01544.13 EMC99567.1 - 0.25 10.3 2.8 0.27 10.2 1.1 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein His_Phos_1 PF00300.17 EMC99568.1 - 6.8e-17 62.0 0.1 9.5e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_42 PF02449.10 EMC99568.1 - 0.015 14.4 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Mmp37 PF09139.6 EMC99568.1 - 0.12 11.4 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 COX15-CtaA PF02628.10 EMC99569.1 - 1.9e-94 315.9 11.8 2.5e-94 315.5 8.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF1049 PF06305.6 EMC99569.1 - 0.92 9.0 6.3 11 5.5 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) FAD_binding_1 PF00667.15 EMC99570.1 - 6.1e-58 195.8 0.0 9.9e-58 195.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EMC99570.1 - 5.7e-12 46.1 0.0 2e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EMC99570.1 - 7.3e-12 45.5 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EMC99570.1 - 5e-05 23.2 0.2 0.00015 21.6 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain PTPA PF03095.10 EMC99572.1 - 8.2e-109 363.3 0.0 1e-108 363.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PAP1 PF08601.5 EMC99573.1 - 0.0027 17.4 6.8 0.0067 16.1 4.7 1.6 1 0 0 1 1 1 1 Transcription factor PAP1 AT_hook PF02178.14 EMC99573.1 - 0.012 15.2 2.2 0.041 13.5 1.5 2.0 1 0 0 1 1 1 0 AT hook motif BTB PF00651.26 EMC99574.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.11 EMC99575.1 - 1.9e-12 46.6 43.4 2.3e-11 43.0 23.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 EMC99575.1 - 0.93 9.0 16.3 0.038 13.4 0.7 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) PY_rept_46 PF09689.5 EMC99576.1 - 0.0048 17.2 0.5 0.0092 16.2 0.3 1.4 1 0 0 1 1 1 1 Plasmodium yoelii repeat (PY_rept_46) Smr PF01713.16 EMC99578.1 - 8.2e-05 22.7 0.1 0.00027 21.0 0.1 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EMC99578.1 - 2.7 8.0 21.7 0.44 10.6 10.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) KH_1 PF00013.24 EMC99579.1 - 5.7e-96 314.1 27.8 1.1e-14 53.8 0.1 12.8 15 0 0 15 15 15 9 KH domain KH_3 PF13014.1 EMC99579.1 - 1.2e-62 206.7 36.1 1.8e-10 40.2 1.4 11.3 12 0 0 12 12 12 9 KH domain SLS PF14611.1 EMC99579.1 - 1.7e-14 53.7 3.4 0.35 10.2 0.0 7.8 5 3 3 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EMC99579.1 - 5.6e-13 48.2 13.7 0.038 13.5 0.2 7.5 7 0 0 7 7 7 4 KH domain KH_4 PF13083.1 EMC99579.1 - 3.3e-05 23.4 2.0 1.7 8.3 0.0 5.8 6 0 0 6 6 6 1 KH domain KH_5 PF13184.1 EMC99579.1 - 0.011 15.4 7.1 1.6 8.6 0.2 4.8 5 0 0 5 5 5 0 NusA-like KH domain YqgF PF14639.1 EMC99579.1 - 0.015 14.8 0.6 6.4 6.3 0.0 3.6 3 0 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 Mito_carr PF00153.22 EMC99581.1 - 2e-55 184.5 2.6 6.1e-21 73.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.3 EMC99582.1 - 8.8e-24 82.7 0.5 1.4e-23 82.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EMC99582.1 - 0.00098 18.9 1.2 0.0017 18.1 0.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC99582.1 - 0.002 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMC99582.1 - 0.0062 16.2 0.3 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EMC99582.1 - 0.0067 15.9 0.9 0.012 15.1 0.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 EMC99582.1 - 0.0081 15.9 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EMC99582.1 - 0.0093 15.6 0.2 0.018 14.6 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Codanin-1_C PF15296.1 EMC99582.1 - 0.022 14.6 3.1 2.2 8.1 0.2 2.5 2 1 0 2 2 2 0 Codanin-1 C-terminus Tmemb_55A PF09788.4 EMC99582.1 - 0.06 12.4 0.1 0.083 11.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A zf-C3HC4_2 PF13923.1 EMC99582.1 - 0.11 12.4 1.0 0.21 11.6 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TMEM154 PF15102.1 EMC99583.1 - 0.0052 16.5 0.3 0.014 15.0 0.2 1.8 1 1 0 1 1 1 1 TMEM154 protein family Amnionless PF14828.1 EMC99583.1 - 0.033 12.7 0.0 0.038 12.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless zf-RING_2 PF13639.1 EMC99584.1 - 6e-09 35.6 4.0 8.5e-09 35.1 2.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC99584.1 - 6.4e-07 29.4 1.6 1.3e-06 28.4 1.1 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC99584.1 - 0.00012 22.0 1.4 0.00021 21.2 1.0 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC99584.1 - 0.00026 20.7 0.9 0.00039 20.2 0.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EMC99584.1 - 0.028 14.0 3.4 0.046 13.3 2.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Adeno_PVIII PF01310.13 EMC99584.1 - 0.034 13.9 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII zf-RING_5 PF14634.1 EMC99584.1 - 0.034 13.8 1.1 0.055 13.2 0.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC99584.1 - 0.057 13.0 1.8 0.35 10.5 1.1 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 EMC99584.1 - 0.079 12.8 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 EMC99584.1 - 0.15 12.0 0.4 0.23 11.4 0.3 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain FtsJ PF01728.14 EMC99585.1 - 2.8e-59 200.1 0.0 3.6e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.11 EMC99586.1 - 2.8e-34 118.4 54.5 4.2e-32 111.2 37.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.7 EMC99586.1 - 0.053 13.4 0.3 0.053 13.4 0.2 3.0 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Sporozoite_P67 PF05642.6 EMC99587.1 - 1.6 6.4 8.5 1.8 6.3 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SIS PF01380.17 EMC99589.1 - 3.8e-10 39.4 0.2 2.5e-09 36.8 0.1 2.1 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EMC99589.1 - 1.1e-06 28.3 0.2 0.00049 19.8 0.2 2.2 1 1 1 2 2 2 2 SIS domain ARID PF01388.16 EMC99591.1 - 1.1e-17 63.6 0.1 3.2e-17 62.1 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Dyp_perox PF04261.7 EMC99592.1 - 2.1e-16 59.5 0.0 1.2e-14 53.8 0.0 2.6 2 1 0 2 2 2 2 Dyp-type peroxidase family Ammonium_transp PF00909.16 EMC99594.1 - 2e-86 289.9 33.5 2.3e-86 289.7 23.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MFS_1 PF07690.11 EMC99595.1 - 7.9e-42 143.2 8.3 7.9e-42 143.2 5.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC99595.1 - 8.3e-06 24.4 1.6 8.3e-06 24.4 1.1 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein Glyco_hydro_28 PF00295.12 EMC99596.1 - 9.9e-52 175.8 13.4 1.9e-51 174.9 9.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 cNMP_binding PF00027.24 EMC99597.1 - 1.1e-33 114.9 0.0 1.1e-17 63.5 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EMC99597.1 - 8.8e-12 43.8 7.4 3.8 7.8 0.0 9.3 9 1 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.28 EMC99597.1 - 1.5e-09 36.5 1.7 15 6.0 0.1 8.9 8 2 1 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 EMC99597.1 - 5.9e-08 32.3 2.0 0.00016 21.3 0.1 4.9 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 EMC99597.1 - 8.6e-08 31.6 0.0 0.28 10.8 0.0 6.3 6 1 2 8 8 8 3 Leucine Rich repeats (2 copies) F-box PF00646.28 EMC99597.1 - 2.8e-05 23.6 0.9 2.8e-05 23.6 0.6 3.5 3 1 0 3 3 3 1 F-box domain F-box-like PF12937.2 EMC99597.1 - 2.9e-05 23.7 1.2 8.2e-05 22.2 0.3 2.2 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 EMC99597.1 - 0.35 11.2 11.3 59 4.5 0.0 7.6 9 0 0 9 9 9 0 Leucine rich repeat DUF504 PF04457.7 EMC99599.1 - 3.5e-08 33.4 0.4 8.3e-08 32.2 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF504) Metallophos PF00149.23 EMC99600.1 - 4.1e-09 36.1 0.1 1.2e-08 34.6 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAN_4 PF14295.1 EMC99601.1 - 8.3e-12 44.6 72.1 0.045 13.4 0.4 11.3 11 0 0 11 11 11 10 PAN domain PAN_3 PF08277.7 EMC99601.1 - 0.0063 16.1 63.5 0.025 14.1 0.1 10.9 11 0 0 11 11 11 6 PAN-like domain Peptidase_M20 PF01546.23 EMC99603.1 - 3e-23 82.3 0.0 6.6e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EMC99603.1 - 3e-20 71.2 0.1 0.00038 20.2 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.9 EMC99603.1 - 1.3e-07 31.3 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.1 EMC99603.1 - 0.057 13.7 0.9 16 5.9 0.0 4.0 3 0 0 3 3 3 0 PQQ-like domain Nucleoporin_N PF08801.6 EMC99603.1 - 0.083 11.6 0.0 0.66 8.6 0.0 2.4 1 1 1 3 3 3 0 Nup133 N terminal like SelR PF01641.13 EMC99604.1 - 4.3e-52 175.0 0.2 5.5e-52 174.6 0.1 1.1 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EMC99604.1 - 0.0083 15.8 0.6 0.57 9.9 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) GFA PF04828.9 EMC99604.1 - 0.02 14.8 1.6 0.49 10.3 0.1 2.3 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EMC99604.1 - 0.072 12.9 3.2 0.7 9.7 2.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EMC99604.1 - 0.087 12.1 1.3 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 EMC99604.1 - 0.4 10.9 1.8 18 5.6 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.1 EMC99604.1 - 0.66 9.8 2.6 6.7 6.6 0.4 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 MS_channel PF00924.13 EMC99605.1 - 6e-14 51.8 0.2 1.2e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EMC99605.1 - 0.0011 18.1 0.1 0.0066 15.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EMC99605.1 - 0.0027 17.7 0.1 0.025 14.7 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC99605.1 - 0.0072 16.1 0.2 0.085 12.7 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EMC99605.1 - 0.0079 15.7 0.1 0.024 14.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC99605.1 - 0.069 12.5 0.0 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 EF hand DUF3176 PF11374.3 EMC99606.1 - 1.3e-08 34.6 4.0 2.4e-08 33.8 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Methyltransf_23 PF13489.1 EMC99607.1 - 4.3e-06 26.5 0.0 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC99607.1 - 0.0054 17.1 0.0 0.023 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TilS PF09179.6 EMC99607.1 - 0.097 12.7 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TilS substrate binding domain Methyltransf_11 PF08241.7 EMC99607.1 - 0.1 13.1 0.0 0.34 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Amidase PF01425.16 EMC99608.1 - 3.9e-95 319.3 0.0 4.6e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.14 EMC99609.1 - 2.4e-70 237.3 0.0 3.3e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMC99609.1 - 2.5e-46 157.3 0.0 4.4e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Lycopene_cycl PF05834.7 EMC99609.1 - 0.051 12.4 0.2 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EMC99609.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Cons_hypoth698 PF03601.9 EMC99610.1 - 0.0068 15.0 0.4 0.0074 14.9 0.3 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 698 DUF1049 PF06305.6 EMC99610.1 - 0.065 12.7 1.5 0.096 12.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) UNC-50 PF05216.8 EMC99610.1 - 0.19 10.8 2.1 0.22 10.6 1.4 1.1 1 0 0 1 1 1 0 UNC-50 family PsaM PF07465.8 EMC99610.1 - 3.7 7.2 9.3 3.7 7.2 5.2 2.0 1 1 0 1 1 1 0 Photosystem I protein M (PsaM) Herpes_US9 PF06072.6 EMC99610.1 - 4.3 7.2 4.8 5.8 6.8 3.3 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 2OG-FeII_Oxy_2 PF13532.1 EMC99612.1 - 5.2e-33 114.5 0.0 1.5e-32 112.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMC99612.1 - 0.0045 17.4 0.0 0.025 15.0 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 EMC99613.1 - 7e-27 94.2 0.1 8.5e-27 94.0 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DASH_Dad4 PF08650.5 EMC99613.1 - 0.046 13.6 0.1 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad4 Helicase_C PF00271.26 EMC99614.1 - 4.4e-11 42.4 0.0 9.2e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMC99614.1 - 0.045 12.5 0.6 0.081 11.7 0.0 1.8 2 0 0 2 2 2 0 SNF2 family N-terminal domain FAM104 PF15434.1 EMC99614.1 - 3 8.1 7.8 0.83 9.8 2.5 2.3 2 0 0 2 2 2 0 Family 104 zf-HIT PF04438.11 EMC99614.1 - 7 6.3 5.4 1.2 8.8 0.1 2.3 2 1 0 2 2 2 0 HIT zinc finger PNP_UDP_1 PF01048.15 EMC99615.1 - 3.5e-37 127.6 0.0 4.4e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Sugar_tr PF00083.19 EMC99616.1 - 5.5e-30 104.3 31.8 2.6e-19 69.1 8.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC99616.1 - 6.9e-11 41.4 44.8 1.9e-10 40.0 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EMC99617.1 - 3.6e-27 95.3 0.8 7.5e-27 94.2 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99617.1 - 2.6e-14 53.5 0.1 4.2e-14 52.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99617.1 - 8e-13 48.4 2.2 3.3e-12 46.4 1.5 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC99617.1 - 2.5e-06 27.1 0.2 6e-06 25.8 0.1 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC99617.1 - 0.00011 22.3 0.1 0.00017 21.6 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMC99617.1 - 0.0014 17.8 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EMC99617.1 - 0.0018 17.1 0.1 0.0028 16.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EMC99617.1 - 0.0064 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family CRCB PF02537.10 EMC99617.1 - 0.031 14.1 0.6 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 CrcB-like protein GTP_EFTU PF00009.22 EMC99618.1 - 2.3e-49 167.3 0.0 4.2e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EMC99618.1 - 6.7e-17 61.3 1.6 1.5e-16 60.2 1.1 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EMC99618.1 - 3e-07 30.4 0.0 1.7e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EMC99618.1 - 6.7e-06 26.1 0.5 1.6e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 EMC99618.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Miro PF08477.8 EMC99618.1 - 0.003 18.0 0.0 0.16 12.4 0.0 2.6 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EMC99618.1 - 0.015 14.9 0.1 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FeoB_N PF02421.13 EMC99618.1 - 0.022 14.0 0.5 0.27 10.5 0.2 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B Med7 PF05983.6 EMC99619.1 - 2.2e-37 128.3 0.1 3e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 MED7 protein E1_dh PF00676.15 EMC99620.1 - 2.5e-86 289.1 0.0 3e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EMC99620.1 - 0.0024 17.4 0.6 0.026 14.1 0.1 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pex14_N PF04695.8 EMC99620.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DXP_synthase_N PF13292.1 EMC99620.1 - 0.09 11.6 0.0 0.37 9.6 0.0 1.9 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Nol1_Nop2_Fmu PF01189.12 EMC99622.1 - 7.8e-16 58.2 0.0 1.5e-14 54.0 0.0 2.6 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EMC99622.1 - 0.0029 17.6 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EMC99622.1 - 0.0055 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Gar1 PF04410.9 EMC99623.1 - 1.1e-40 138.6 0.0 1.1e-40 138.6 0.0 2.0 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region 7tm_2 PF00002.19 EMC99624.1 - 3.8e-06 26.1 8.3 2.2e-05 23.6 6.0 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Protocadherin PF08374.6 EMC99624.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protocadherin PsbX PF06596.6 EMC99624.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) CRAL_TRIO PF00650.15 EMC99625.1 - 3.9e-47 159.6 0.0 6e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC99625.1 - 3e-14 52.8 0.3 8.8e-14 51.3 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMC99625.1 - 1.5e-10 41.1 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.24 EMC99627.1 - 4.4e-10 39.6 0.0 1.4e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 PH domain eIF-3c_N PF05470.7 EMC99627.1 - 0.019 13.1 0.2 0.026 12.6 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus XPG_N PF00752.12 EMC99628.1 - 4.5e-25 87.8 0.0 1.1e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EMC99628.1 - 4.2e-23 81.2 0.0 8.2e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EMC99628.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EMC99628.1 - 0.015 15.5 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF2962 PF11176.3 EMC99629.1 - 1.5e-46 157.8 4.7 1.6e-46 157.6 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Cucumo_2B PF03263.8 EMC99629.1 - 0.025 14.8 2.0 0.045 14.0 1.4 1.5 1 0 0 1 1 1 0 Cucumovirus protein 2B Phasin PF05597.6 EMC99629.1 - 0.06 13.1 0.8 0.12 12.1 0.6 1.6 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FAD_binding_3 PF01494.14 EMC99630.1 - 1.6e-15 57.0 5.5 6e-14 51.8 3.8 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC99630.1 - 0.00021 20.3 2.1 0.0021 17.0 1.8 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC99630.1 - 0.00053 19.9 2.2 0.0014 18.6 0.9 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMC99630.1 - 0.003 16.4 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Amino_oxidase PF01593.19 EMC99630.1 - 0.0032 16.6 0.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EMC99630.1 - 0.0068 15.3 0.2 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC99630.1 - 0.065 13.0 0.8 0.24 11.2 0.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC99630.1 - 0.068 13.5 0.6 0.22 11.9 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC99630.1 - 0.078 12.7 0.6 0.53 10.0 0.5 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FSH1 PF03959.8 EMC99631.1 - 2.2e-30 105.7 0.0 2.8e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EMC99631.1 - 1.3e-06 28.2 0.0 2.2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC99631.1 - 0.00014 21.7 0.6 0.004 17.0 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC99631.1 - 0.041 13.3 0.0 4.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Aminotran_3 PF00202.16 EMC99632.1 - 4.2e-44 150.7 0.0 2e-43 148.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 EMC99632.1 - 3.5e-37 127.9 0.0 5.9e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EMC99632.1 - 0.044 13.1 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMC99632.1 - 0.055 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC99632.1 - 0.11 12.6 0.1 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Aminotran_1_2 PF00155.16 EMC99633.1 - 8.5e-39 133.5 0.0 9.9e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMC99633.1 - 0.00072 17.9 0.0 0.0011 17.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 EMC99633.1 - 0.0025 16.6 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Complex1_LYR PF05347.10 EMC99634.1 - 7.1e-09 35.3 0.4 1e-08 34.8 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMC99634.1 - 1.2e-06 28.6 0.2 1.6e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like 2-oxoacid_dh PF00198.18 EMC99635.1 - 1.1e-79 267.0 0.3 1.4e-79 266.6 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMC99635.1 - 1.4e-18 66.2 1.0 2.8e-18 65.3 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMC99635.1 - 0.00044 19.8 0.2 0.19 11.3 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like DUF605 PF04652.11 EMC99635.1 - 0.023 14.1 19.8 0.029 13.7 13.8 1.2 1 0 0 1 1 1 0 Vta1 like GCV_H PF01597.14 EMC99635.1 - 0.031 13.9 0.2 0.067 12.8 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein PAT1 PF09770.4 EMC99635.1 - 0.52 8.4 18.2 0.63 8.2 12.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Histone PF00125.19 EMC99636.1 - 8.8e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC99636.1 - 1.3e-05 25.1 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC99637.1 - 2.3e-22 78.8 0.2 3.3e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC99637.1 - 4.5e-05 23.4 0.4 0.00011 22.2 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC99637.1 - 0.00023 21.3 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EMC99637.1 - 0.022 15.2 0.2 0.031 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EMC99637.1 - 0.022 14.1 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.14 EMC99638.1 - 9.9e-92 307.0 0.0 1.3e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 R3H PF01424.17 EMC99639.1 - 7.7e-13 47.9 0.1 1.4e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 R3H domain G-patch PF01585.18 EMC99639.1 - 2.1e-12 46.6 1.3 5.1e-12 45.3 0.9 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC99639.1 - 7.1e-08 32.1 0.9 1.7e-07 30.9 0.6 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site TSP9 PF11493.3 EMC99639.1 - 0.0011 19.4 3.9 0.0021 18.5 2.7 1.5 1 0 0 1 1 1 1 Thylakoid soluble phosphoprotein TSP9 VHS PF00790.14 EMC99640.1 - 5.9e-46 155.6 0.2 2.7e-45 153.4 0.0 2.2 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 EMC99640.1 - 6.4e-27 93.4 1.2 1.7e-26 92.1 0.2 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EMC99640.1 - 2.1e-20 73.1 0.5 5.6e-20 71.7 0.4 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Coatamer_beta_C PF07718.7 EMC99640.1 - 0.0016 18.1 1.1 0.003 17.2 0.0 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region Mei5 PF10376.4 EMC99640.1 - 0.021 14.3 4.6 0.031 13.8 1.8 2.1 1 1 1 2 2 2 0 Double-strand recombination repair protein DASH_Dad2 PF08654.5 EMC99640.1 - 0.13 12.3 0.0 0.13 12.3 0.0 2.1 3 0 0 3 3 3 0 DASH complex subunit Dad2 DUF367 PF04034.8 EMC99641.1 - 3.6e-48 162.3 0.0 5e-48 161.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EMC99641.1 - 2.5e-09 36.5 0.1 4.1e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ribosomal_L33 PF00471.15 EMC99645.1 - 4.4e-05 23.6 0.0 5.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 DUF641 PF04859.7 EMC99646.1 - 0.00013 21.7 3.1 0.00013 21.7 2.2 6.7 3 1 4 7 7 7 1 Plant protein of unknown function (DUF641) Zn_clus PF00172.13 EMC99648.1 - 1.2e-05 25.1 10.2 1.9e-05 24.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.16 EMC99649.1 - 4e-09 36.0 0.1 1.5e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Cellulase PF00150.13 EMC99650.1 - 6.6e-13 48.4 0.4 6.6e-13 48.4 0.3 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 EMC99652.1 - 1.2e-17 63.9 0.0 6.2e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99652.1 - 0.00046 19.3 0.0 0.0042 16.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC99652.1 - 0.051 12.5 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PAT1 PF09770.4 EMC99652.1 - 4.6 5.3 30.1 6.3 4.9 20.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2433 PF10360.4 EMC99653.1 - 3.9e-49 166.3 0.0 6.3e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EMC99653.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF4283 PF14111.1 EMC99653.1 - 0.25 10.4 0.0 0.47 9.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) TFIIA PF03153.8 EMC99653.1 - 0.27 11.0 15.7 0.4 10.5 10.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.17 EMC99656.1 - 7e-157 522.4 0.1 7.9e-157 522.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMC99656.1 - 4.4e-06 26.0 0.0 9.4e-06 25.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) zf-C2H2_2 PF12756.2 EMC99657.1 - 8.2e-35 118.9 7.9 2.8e-29 101.2 1.1 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMC99657.1 - 4.9e-08 32.8 15.3 0.003 17.6 0.6 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC99657.1 - 2.6e-06 27.4 0.6 2.6e-06 27.4 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type SnoaL_2 PF12680.2 EMC99657.1 - 0.0041 17.5 0.1 0.012 15.9 0.1 1.8 1 0 0 1 1 1 1 SnoaL-like domain zf-C2H2 PF00096.21 EMC99657.1 - 0.58 10.6 21.3 0.28 11.5 0.4 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMC99657.1 - 0.75 9.7 10.3 0.3 11.0 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger AKAP95 PF04988.7 EMC99657.1 - 1.2 8.8 7.5 0.3 10.8 0.1 3.1 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Prefoldin_3 PF13758.1 EMC99658.1 - 4.7e-18 64.7 1.1 8.5e-17 60.7 0.1 2.8 3 0 0 3 3 3 1 Prefoldin subunit DUF3835 PF12927.2 EMC99658.1 - 1.7e-15 57.6 0.8 2.4e-14 54.0 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3835) Mod_r PF07200.8 EMC99658.1 - 0.33 10.8 7.9 1.2 9.0 0.3 3.5 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein MAT1 PF06391.8 EMC99659.1 - 2.4e-36 125.2 18.3 3.2e-36 124.8 12.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EMC99659.1 - 6.3e-05 22.5 6.1 0.00014 21.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC99659.1 - 0.00032 20.4 7.0 0.00054 19.7 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC99659.1 - 0.00086 19.2 9.2 0.0017 18.3 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EMC99659.1 - 0.0032 17.0 6.1 0.035 13.6 2.1 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF86 PF01934.12 EMC99659.1 - 0.0056 16.3 0.1 0.024 14.2 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF86 zf-C3HC4_3 PF13920.1 EMC99659.1 - 0.0056 16.3 8.9 0.014 15.0 6.2 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC99659.1 - 0.031 14.0 10.5 0.21 11.3 7.6 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Tim17 PF02466.14 EMC99660.1 - 2.8e-34 117.9 5.9 3.6e-34 117.5 4.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EMC99660.1 - 0.052 13.3 0.0 0.095 12.4 0.0 1.5 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Pkinase PF00069.20 EMC99661.1 - 2.1e-41 141.7 0.0 8.2e-41 139.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99661.1 - 2.7e-31 108.5 0.0 4.3e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC99661.1 - 1.3e-06 27.5 0.0 3.3e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC99661.1 - 0.0052 16.5 0.5 2.3 7.8 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC99661.1 - 0.02 13.9 0.1 0.043 12.8 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUP PF06516.6 EMC99662.1 - 1.1e-114 382.5 0.3 1.2e-114 382.3 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) PLA2_B PF01735.13 EMC99663.1 - 1e-178 594.5 6.1 2.2e-178 593.4 4.3 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain adh_short PF00106.20 EMC99664.1 - 1e-17 64.5 0.0 2.9e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99664.1 - 3.9e-05 23.5 0.0 6.4e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC99664.1 - 0.00094 18.6 0.1 0.0079 15.6 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC99664.1 - 0.0024 17.9 0.1 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EMC99664.1 - 0.0039 16.8 0.0 0.072 12.7 0.0 2.2 2 0 0 2 2 2 1 KR domain UPF0146 PF03686.8 EMC99664.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Flavokinase PF01687.12 EMC99666.1 - 1.3e-37 128.4 0.0 1.8e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.19 EMC99667.1 - 0.002 17.8 0.0 0.021 14.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 EMC99667.1 - 0.019 14.8 8.6 0.019 14.8 6.0 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMC99669.1 - 2e-39 135.3 29.6 2e-39 135.3 20.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC99669.1 - 0.00026 19.3 2.7 0.00044 18.5 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.7 EMC99669.1 - 0.0027 16.1 0.7 0.0042 15.5 0.0 1.6 2 0 0 2 2 2 1 Ferroportin1 (FPN1) DUF2721 PF11026.3 EMC99669.1 - 1.6 8.3 0.0 1.6 8.3 0.0 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF2721) Flavoprotein PF02441.14 EMC99670.1 - 1.9e-16 59.9 0.0 4.4e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Flavoprotein Ank_2 PF12796.2 EMC99670.1 - 0.0012 19.1 0.0 0.89 9.9 0.0 2.5 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) PHY PF00360.15 EMC99671.1 - 6e-29 100.4 0.0 1.5e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EMC99671.1 - 7.4e-16 57.8 0.1 1.8e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 EMC99671.1 - 1e-15 58.2 0.0 4.2e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.19 EMC99671.1 - 6.3e-15 55.1 0.0 3.8e-14 52.6 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMC99671.1 - 6.9e-13 48.3 0.5 2.1e-12 46.8 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EMC99671.1 - 2e-08 34.6 0.0 6.7e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 PAS fold PH_8 PF15409.1 EMC99671.1 - 0.13 12.2 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain UCH_1 PF13423.1 EMC99672.1 - 7e-51 173.4 0.1 1e-50 172.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EMC99672.1 - 2.1e-19 70.3 0.0 5.2e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EMC99672.1 - 0.00059 19.0 0.0 0.0028 16.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PEPCK_ATP PF01293.15 EMC99673.1 - 3.4e-217 721.5 0.0 3.9e-217 721.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EMC99673.1 - 0.0042 17.3 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMC99673.1 - 0.012 15.4 0.1 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMC99673.1 - 0.066 12.5 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMC99673.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Zn_clus PF00172.13 EMC99675.1 - 2.3e-10 40.1 8.1 3.4e-10 39.6 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phasin PF05597.6 EMC99676.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.8 3 2 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SNF2_N PF00176.18 EMC99677.1 - 5.3e-69 232.2 0.0 7.1e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EMC99677.1 - 1.4e-17 63.5 0.0 2.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 EMC99677.1 - 5.2e-11 42.1 8.2 1.1e-10 41.1 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC99677.1 - 1.5e-08 34.4 9.0 1.5e-08 34.4 6.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EMC99677.1 - 2.4e-08 33.7 0.0 5.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EMC99677.1 - 3.6e-07 29.7 9.1 7.5e-07 28.7 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC99677.1 - 9.6e-07 28.5 7.9 1.8e-06 27.7 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EMC99677.1 - 1.3e-06 27.9 6.0 1.3e-06 27.9 4.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC99677.1 - 1.4e-06 27.9 6.7 2.7e-06 26.9 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC99677.1 - 1.6e-06 28.1 3.3 5.2e-06 26.4 2.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMC99677.1 - 3.4e-06 26.6 5.8 1.6e-05 24.5 4.3 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EMC99677.1 - 6.6e-05 22.3 6.9 0.00017 21.0 4.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DEAD PF00270.24 EMC99677.1 - 0.0019 17.6 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_6 PF14835.1 EMC99677.1 - 0.0027 17.4 3.3 0.0027 17.4 2.3 1.7 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EMC99677.1 - 0.0053 16.5 2.0 0.014 15.2 1.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EMC99677.1 - 0.0086 16.0 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 U-box domain HDA2-3 PF11496.3 EMC99677.1 - 0.086 11.6 0.0 0.84 8.3 0.0 2.4 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_4 PF14570.1 EMC99677.1 - 0.18 11.3 4.1 0.63 9.6 2.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 EMC99677.1 - 0.69 9.4 3.0 7.6 6.0 0.3 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif Smg4_UPF3 PF03467.10 EMC99678.1 - 0.003 17.5 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family Reductase_C PF14759.1 EMC99678.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Reductase C-terminal Transket_pyr PF02779.19 EMC99681.1 - 5.3e-45 153.0 0.1 7.8e-45 152.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMC99681.1 - 6.6e-31 106.8 0.0 4.3e-30 104.2 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain ARGLU PF15346.1 EMC99682.1 - 4 7.2 13.0 4.1 7.1 9.0 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 PH PF00169.24 EMC99683.1 - 1.9e-06 27.9 0.0 3.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 EMC99683.1 - 0.021 14.3 0.0 0.24 10.9 0.0 2.0 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Zds_C PF08632.5 EMC99684.1 - 1.9e-30 104.0 1.3 3.6e-30 103.1 0.9 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Miro PF08477.8 EMC99685.1 - 9.1e-35 119.7 0.0 2.1e-18 66.9 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EMC99685.1 - 1e-30 104.7 0.2 2.3e-30 103.7 0.1 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 EMC99685.1 - 9.9e-30 102.1 0.0 2.6e-29 100.8 0.0 1.7 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 EMC99685.1 - 6.4e-25 87.4 0.0 1.5e-15 56.9 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EMC99685.1 - 2.6e-09 37.0 0.0 0.0011 18.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EMC99685.1 - 7.5e-07 29.1 0.7 0.016 15.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC99685.1 - 6.8e-06 25.0 1.0 0.054 12.8 0.1 2.7 2 0 0 2 2 2 2 EF hand Dynamin_N PF00350.18 EMC99685.1 - 1.4e-05 24.9 0.1 0.091 12.5 0.0 3.0 3 0 0 3 3 3 2 Dynamin family EF-hand_6 PF13405.1 EMC99685.1 - 2.8e-05 23.6 4.4 0.11 12.4 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.1 EMC99685.1 - 0.00087 19.3 0.0 0.84 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_5 PF13202.1 EMC99685.1 - 0.0019 17.4 3.4 0.71 9.3 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_28 PF13521.1 EMC99685.1 - 0.0022 18.0 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EMC99685.1 - 0.0033 17.1 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EMC99685.1 - 0.0051 16.9 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EMC99685.1 - 0.0075 15.7 0.0 3.8 6.8 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 EMC99685.1 - 0.0082 16.2 0.0 5.4 7.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase EF-hand_8 PF13833.1 EMC99685.1 - 0.02 14.4 1.6 2.4 7.8 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain pair AAA_14 PF13173.1 EMC99685.1 - 0.038 13.8 0.0 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EMC99685.1 - 0.063 12.5 0.1 4.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B MobB PF03205.9 EMC99685.1 - 0.16 11.6 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B WD40 PF00400.27 EMC99686.1 - 3.8e-24 83.6 5.2 1.4e-05 24.7 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC99686.1 - 0.0018 17.9 0.1 0.057 13.1 0.0 2.2 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMC99686.1 - 0.0084 14.4 0.0 0.023 12.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain IKI3 PF04762.7 EMC99686.1 - 0.012 13.4 0.0 0.019 12.7 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Proteasome_A_N PF10584.4 EMC99686.1 - 0.026 13.8 0.2 4.6 6.6 0.0 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 EMC99686.1 - 0.039 13.6 0.0 12 5.7 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1273 PF06908.6 EMC99686.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Arrestin_C PF02752.17 EMC99687.1 - 3.8e-13 49.6 0.1 8e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMC99687.1 - 2.1e-09 37.3 0.0 4e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EMC99687.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like zf-Di19 PF05605.7 EMC99688.1 - 0.017 15.2 0.1 0.032 14.3 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EMC99688.1 - 0.13 11.9 0.2 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Grp1_Fun34_YaaH PF01184.14 EMC99689.1 - 1.5e-72 243.2 16.9 1.8e-72 243.0 11.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DIOX_N PF14226.1 EMC99690.1 - 5.9e-12 46.1 0.0 9.5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMC99690.1 - 2.1e-10 40.7 0.0 3.6e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ODAM PF15424.1 EMC99690.1 - 0.035 13.6 0.0 0.18 11.2 0.0 2.0 3 0 0 3 3 3 0 Odontogenic ameloblast-associated family Ald_Xan_dh_C2 PF02738.13 EMC99690.1 - 0.08 11.2 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Peptidase_M24 PF00557.19 EMC99691.1 - 7e-49 166.2 0.0 6.7e-48 163.0 0.0 2.2 2 1 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EMC99691.1 - 1.3e-39 134.6 0.0 2.5e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.13 EMC99691.1 - 0.049 14.1 0.0 0.22 12.0 0.0 2.1 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain SIR2 PF02146.12 EMC99692.1 - 2.2e-37 128.4 0.0 5.1e-37 127.3 0.0 1.6 1 1 0 1 1 1 1 Sir2 family DUF2263 PF10021.4 EMC99692.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) PgaD PF13994.1 EMC99692.1 - 0.18 11.3 0.3 0.52 9.7 0.1 1.8 2 0 0 2 2 2 0 PgaD-like protein Pkinase PF00069.20 EMC99693.1 - 3.3e-61 206.6 0.0 4.4e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99693.1 - 6e-31 107.4 0.0 8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC99693.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC99693.1 - 0.0024 17.6 1.2 0.007 16.1 0.1 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC99693.1 - 0.007 15.4 0.2 0.013 14.5 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 EMC99694.1 - 3.1e-36 123.8 0.1 3.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UCH PF00443.24 EMC99695.1 - 1.5e-56 191.5 0.0 2e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC99695.1 - 2.5e-23 82.9 0.0 6.3e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EMC99695.1 - 0.0026 18.0 0.0 0.0091 16.3 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain STIL_N PF15253.1 EMC99695.1 - 0.088 11.4 1.7 0.15 10.7 1.2 1.3 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Bcl-2 PF00452.14 EMC99695.1 - 0.16 12.1 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family VHS PF00790.14 EMC99696.1 - 1.5e-39 134.8 1.3 1.2e-38 131.9 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EMC99696.1 - 1.5e-16 60.0 1.0 2.9e-16 59.1 0.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EMC99696.1 - 0.0014 17.9 16.4 0.054 13.0 0.3 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EMC99696.1 - 0.056 13.3 0.4 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 EMC99696.1 - 0.063 13.0 2.2 0.12 12.1 1.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 EMC99696.1 - 0.31 10.7 1.4 0.59 9.8 1.0 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TPR_20 PF14561.1 EMC99696.1 - 0.44 10.6 4.8 3 8.0 1.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.8 EMC99699.1 - 2.2e-45 155.2 14.5 3.2e-44 151.4 10.0 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF572) Pkinase PF00069.20 EMC99700.1 - 1.9e-69 233.6 0.0 2.5e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99700.1 - 8.6e-30 103.6 0.0 1.1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC99700.1 - 0.028 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC99700.1 - 0.13 11.2 0.0 0.35 9.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Rad4 PF03835.10 EMC99701.1 - 4.1e-32 110.5 0.0 8.7e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EMC99701.1 - 6.2e-28 96.3 0.1 1.2e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EMC99701.1 - 2.2e-19 68.7 0.1 4.5e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EMC99701.1 - 6.5e-15 55.1 1.0 2e-14 53.6 0.1 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EMC99701.1 - 0.00045 20.3 0.0 0.0027 17.8 0.0 2.4 1 1 0 1 1 1 1 Transglutaminase-like superfamily DUF2184 PF09950.4 EMC99701.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) NTP_transferase PF00483.18 EMC99702.1 - 6.8e-31 107.4 0.0 9e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EMC99702.1 - 2.1e-09 36.4 6.1 4.7e-06 25.8 0.1 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMC99702.1 - 1.6e-07 31.5 0.0 2.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2968 PF11180.3 EMC99702.1 - 0.018 14.4 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IspD PF01128.14 EMC99702.1 - 0.05 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_tranf_2_3 PF13641.1 EMC99702.1 - 0.091 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF3722 PF12519.3 EMC99703.1 - 0.078 12.1 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) Dynamin_N PF00350.18 EMC99704.1 - 5.7e-18 65.2 0.0 1.6e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EMC99704.1 - 2.8e-11 42.7 0.1 9.5e-11 41.0 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 EMC99704.1 - 0.00012 21.9 0.0 0.00035 20.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Miro PF08477.8 EMC99704.1 - 0.0027 18.2 0.0 0.0069 16.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein CCDC71L PF15374.1 EMC99704.1 - 0.022 14.0 0.1 0.036 13.3 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L MMR_HSR1 PF01926.18 EMC99704.1 - 0.022 14.7 0.0 0.24 11.3 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EMC99704.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EMC99704.1 - 0.058 13.6 0.0 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EMC99704.1 - 0.059 13.6 2.5 0.22 11.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Pyridox_oxidase PF01243.15 EMC99705.1 - 1.4e-07 31.4 0.0 0.0047 16.8 0.0 2.8 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EMC99705.1 - 0.002 18.2 0.1 0.041 14.0 0.0 2.5 1 1 1 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMC99705.1 - 0.2 11.5 0.1 0.46 10.3 0.1 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF4131 PF13567.1 EMC99708.1 - 0.37 10.1 9.6 1.1 8.6 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HemY_N PF07219.8 EMC99708.1 - 5.9 6.4 6.8 0.5 9.9 0.2 2.4 3 0 0 3 3 3 0 HemY protein N-terminus Tannase PF07519.6 EMC99709.1 - 7e-95 318.4 8.1 7e-95 318.4 5.6 1.5 2 0 0 2 2 2 1 Tannase and feruloyl esterase DUF500 PF04366.7 EMC99710.1 - 8.2e-44 148.0 0.3 1.2e-43 147.4 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EMC99710.1 - 2e-14 52.6 0.2 8.6e-14 50.6 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMC99710.1 - 3.2e-13 48.9 0.1 6.5e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC99710.1 - 1.5e-10 40.4 0.0 2.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Synaptobrevin PF00957.16 EMC99711.1 - 0.033 13.7 1.0 0.063 12.8 0.6 1.6 1 1 1 2 2 2 0 Synaptobrevin DUF4349 PF14257.1 EMC99711.1 - 0.039 13.1 0.3 0.043 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Rootletin PF15035.1 EMC99711.1 - 0.12 12.3 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ArfGap PF01412.13 EMC99712.1 - 6.7e-42 141.9 0.9 1.2e-41 141.1 0.7 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf tRNA-synt_2 PF00152.15 EMC99714.1 - 2.1e-80 270.0 0.3 3.4e-80 269.3 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) TFIIS_M PF07500.9 EMC99714.1 - 1.9e-17 63.3 1.6 1.9e-17 63.3 1.1 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EMC99714.1 - 3.7e-14 53.2 0.0 8e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EMC99714.1 - 4.5e-08 32.6 7.5 9.3e-08 31.6 5.2 1.6 1 0 0 1 1 1 1 PHD-finger tRNA_anti-codon PF01336.20 EMC99714.1 - 5.1e-07 29.4 0.1 1.6e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMC99714.1 - 7.3e-06 25.3 0.1 0.0052 16.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Spc7 PF08317.6 EMC99715.1 - 0.019 13.6 7.5 0.033 12.8 5.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Prefoldin PF02996.12 EMC99715.1 - 0.019 14.6 3.2 2.9 7.5 0.0 3.3 3 1 0 3 3 3 0 Prefoldin subunit AAA_13 PF13166.1 EMC99715.1 - 0.028 12.8 9.4 0.049 12.1 6.5 1.3 1 0 0 1 1 1 0 AAA domain PspA_IM30 PF04012.7 EMC99715.1 - 0.15 11.3 8.2 4.6 6.5 5.4 2.4 1 1 0 1 1 1 0 PspA/IM30 family DUF972 PF06156.8 EMC99715.1 - 0.5 10.7 7.5 7.5 6.9 2.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 EMC99715.1 - 0.65 9.7 9.7 1.5 8.5 2.2 2.5 1 1 0 2 2 2 0 Laminin Domain II Pex24p PF06398.6 EMC99715.1 - 1.1 7.9 5.3 1.9 7.2 3.1 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Tht1 PF04163.7 EMC99715.1 - 2.3 6.4 11.6 3.3 5.9 0.0 2.6 2 1 0 2 2 2 0 Tht1-like nuclear fusion protein IncA PF04156.9 EMC99715.1 - 3.4 7.2 19.7 9.1 5.8 4.0 3.1 2 1 1 3 3 3 0 IncA protein DUF1664 PF07889.7 EMC99715.1 - 5.6 6.7 8.2 4.1 7.2 0.6 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_L6 PF00347.18 EMC99716.1 - 3.2e-25 88.4 0.2 1.3e-13 51.2 0.0 3.3 4 0 0 4 4 4 2 Ribosomal protein L6 COX5B PF01215.14 EMC99717.1 - 9.3e-40 135.4 0.0 1.3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb NUDIX PF00293.23 EMC99718.1 - 1.8e-13 50.2 0.0 3.9e-11 42.7 0.0 3.0 1 1 0 1 1 1 1 NUDIX domain ADH_N PF08240.7 EMC99719.1 - 2.7e-06 27.1 0.0 1.1e-05 25.1 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC99719.1 - 0.027 14.0 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1122 PF06557.6 EMC99719.1 - 0.14 11.3 0.1 1.4 8.0 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1122) Kinesin PF00225.18 EMC99720.1 - 2.2e-112 375.0 0.0 3.4e-112 374.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 EMC99720.1 - 0.024 14.5 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC99723.1 - 1.5e-32 112.7 0.0 3.7e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMC99723.1 - 6e-29 101.3 10.5 1.5e-28 99.9 7.3 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EMC99723.1 - 2.6e-07 30.1 0.3 7.6e-06 25.3 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC99723.1 - 6.5e-05 23.0 0.0 0.23 11.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EMC99723.1 - 0.00077 19.4 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EMC99723.1 - 0.0023 17.1 0.0 0.0062 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMC99723.1 - 0.0043 17.1 0.3 0.039 14.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EMC99723.1 - 0.0046 16.8 1.2 0.03 14.2 0.2 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EMC99723.1 - 0.0047 16.4 0.2 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 EMC99723.1 - 0.017 14.8 0.2 0.22 11.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Alk_phosphatase PF00245.15 EMC99724.1 - 2.5e-110 369.0 0.1 3.2e-110 368.7 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EMC99724.1 - 8.9e-06 25.2 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EMC99724.1 - 0.066 12.9 3.0 0.089 12.5 0.1 2.5 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Grp1_Fun34_YaaH PF01184.14 EMC99725.1 - 2.4e-22 79.2 22.8 3.1e-22 78.9 15.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3630 PF12305.3 EMC99726.1 - 0.0098 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3630) zf-C3HC PF07967.8 EMC99727.1 - 2.1e-39 134.3 0.1 2.9e-28 98.3 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EMC99727.1 - 7.8e-21 73.7 0.0 5.3e-20 71.0 0.0 2.3 2 0 0 2 2 2 1 Rsm1-like PsaL PF02605.10 EMC99727.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI AA_permease_2 PF13520.1 EMC99728.1 - 1.2e-42 145.9 45.1 1.4e-42 145.7 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC99728.1 - 8.5e-19 67.2 40.3 1.1e-18 66.8 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease PhyH PF05721.8 EMC99729.1 - 0.0024 17.9 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 EMC99730.1 - 1.1e-13 50.6 0.0 1.5e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC99730.1 - 1.5e-08 34.4 10.4 3.3e-08 33.3 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_MT_bd PF06657.8 EMC99731.1 - 2.4e-23 81.8 0.4 2.4e-23 81.8 0.3 4.3 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EMC99731.1 - 1.7e-11 43.8 0.2 1.7e-11 43.8 0.2 4.0 3 1 1 4 4 4 2 Centrosome localisation domain of PPC89 CCDC92 PF14916.1 EMC99731.1 - 0.026 14.1 3.0 0.18 11.4 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DUF904 PF06005.7 EMC99731.1 - 0.98 9.7 20.8 0.083 13.1 1.8 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF904) Diphthamide_syn PF01866.12 EMC99732.1 - 4.2e-51 174.0 0.0 2.7e-50 171.3 0.0 2.1 2 1 0 2 2 2 1 Putative diphthamide synthesis protein DDE_3 PF13358.1 EMC99733.1 - 3e-05 23.8 0.0 4.8e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease RCC1 PF00415.13 EMC99734.1 - 1.9e-23 82.4 0.3 1.4e-05 25.2 0.0 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EMC99734.1 - 1.3e-14 54.0 0.0 9.6e-11 41.6 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EMC99734.1 - 4e-10 39.9 0.8 2.1e-05 24.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EMC99734.1 - 4.3e-07 29.3 4.0 2.7e-06 26.8 0.3 3.4 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 EMC99734.1 - 3.9e-05 23.9 0.1 0.0001 22.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMC99734.1 - 5.8e-05 22.9 0.8 0.027 14.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EMC99734.1 - 0.001 19.2 0.4 2.1 8.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC99734.1 - 0.12 12.2 0.3 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat GMC_oxred_N PF00732.14 EMC99736.1 - 3e-55 187.4 0.0 4.3e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC99736.1 - 4.7e-35 120.9 0.0 8.1e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMC99736.1 - 8.3e-07 28.1 0.1 0.023 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EMC99736.1 - 0.012 14.1 0.0 0.85 8.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 EMC99736.1 - 0.023 13.6 1.2 2.2 7.1 0.2 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 EMC99736.1 - 0.063 12.3 0.0 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NUP50 PF08911.6 EMC99738.1 - 6 7.3 8.6 1.1 9.6 0.4 2.7 2 1 1 3 3 3 0 NUP50 (Nucleoporin 50 kDa) zf-RING_4 PF14570.1 EMC99740.1 - 5.5e-20 70.6 12.6 1e-19 69.8 8.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EMC99740.1 - 2.9e-09 36.4 0.0 8.4e-09 34.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC99740.1 - 3.9e-06 26.6 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC99740.1 - 0.00029 20.7 0.0 0.00072 19.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EMC99740.1 - 0.00038 19.7 3.7 0.00038 19.7 2.6 2.0 3 0 0 3 3 3 1 Rtf2 RING-finger Baculo_IE-1 PF05290.6 EMC99740.1 - 0.0026 17.5 5.5 0.0059 16.3 3.8 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) FYVE_2 PF02318.11 EMC99740.1 - 0.0057 16.5 3.8 0.017 14.9 2.6 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.16 EMC99740.1 - 0.01 15.7 3.5 0.023 14.5 2.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.20 EMC99740.1 - 0.023 14.3 9.9 0.055 13.1 6.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EMC99740.1 - 0.029 14.1 6.1 0.083 12.6 3.3 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger Prok-RING_4 PF14447.1 EMC99740.1 - 1.1 8.8 9.7 0.33 10.5 2.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Complex1_30kDa PF00329.14 EMC99741.1 - 6e-36 122.7 0.1 8.8e-36 122.2 0.1 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HAMP PF00672.20 EMC99741.1 - 1 9.6 2.7 8.5 6.6 1.9 2.3 1 1 0 1 1 1 0 HAMP domain MFS_1 PF07690.11 EMC99742.1 - 1.5e-42 145.5 43.9 1.5e-42 145.5 30.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC99742.1 - 7.4e-16 57.7 8.0 7.4e-16 57.7 5.5 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter Vps51 PF08700.6 EMC99742.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Vps51/Vps67 PAP2 PF01569.16 EMC99743.1 - 5.2e-22 77.9 1.0 5.2e-22 77.9 0.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily AGTRAP PF06396.6 EMC99743.1 - 0.018 14.7 0.5 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) RseC_MucC PF04246.7 EMC99743.1 - 0.77 9.3 4.1 11 5.6 0.3 3.1 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Fe-ADH PF00465.14 EMC99744.1 - 2.1e-100 335.9 0.0 2.7e-100 335.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMC99744.1 - 6.3e-15 55.1 0.0 4e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EMC99744.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Toprim_3 PF13362.1 EMC99744.1 - 0.16 12.2 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Toprim domain 2-Hacid_dh_C PF02826.14 EMC99745.1 - 3.6e-56 189.1 0.0 7.2e-56 188.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC99745.1 - 1.6e-35 121.4 0.2 3e-35 120.5 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 EMC99745.1 - 0.017 14.5 0.4 0.21 11.0 0.0 2.9 2 0 0 2 2 2 0 ACT domain UDPG_MGDP_dh_C PF03720.10 EMC99745.1 - 0.063 13.4 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AdoHcyase_NAD PF00670.16 EMC99745.1 - 0.067 13.0 1.6 0.088 12.6 0.2 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HECT PF00632.20 EMC99746.1 - 4.2e-82 275.8 0.0 6.8e-82 275.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EMC99746.1 - 6e-05 22.7 1.5 0.76 9.6 0.0 5.6 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EMC99746.1 - 0.0023 17.8 1.1 0.14 12.3 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EMC99746.1 - 0.044 14.2 0.3 1.1 9.8 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat RRN3 PF05327.6 EMC99746.1 - 0.23 9.5 4.7 0.61 8.1 3.3 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TraQ PF09679.5 EMC99747.1 - 0.0033 17.2 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) Paxillin PF03535.8 EMC99747.1 - 0.11 12.3 3.2 0.27 11.0 0.1 2.4 2 0 0 2 2 2 0 Paxillin family DegT_DnrJ_EryC1 PF01041.12 EMC99748.1 - 0.12 11.3 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TauD PF02668.11 EMC99749.1 - 7.2e-47 160.2 0.2 8.3e-47 160.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aminotran_1_2 PF00155.16 EMC99750.1 - 3.3e-40 138.1 0.0 5.1e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 EMC99751.1 - 5e-23 81.3 11.6 5e-23 81.3 8.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC99751.1 - 0.031 14.0 0.3 0.43 10.4 0.1 2.9 2 0 0 2 2 2 0 MFS_1 like family Chromo PF00385.19 EMC99752.1 - 1.8e-13 49.9 3.0 2.8e-13 49.3 0.4 2.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EMC99752.1 - 2.3e-06 27.3 0.1 8.3e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Chromo shadow domain P_gingi_FimA PF06321.6 EMC99752.1 - 0.0071 15.5 0.3 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 Major fimbrial subunit protein (FimA) Cpn60_TCP1 PF00118.19 EMC99753.1 - 5.2e-143 477.1 4.2 5.9e-143 476.9 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-DNA_Pol PF08996.5 EMC99754.1 - 0.006 15.9 2.9 0.78 9.0 0.4 2.4 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger HypA PF01155.14 EMC99754.1 - 0.062 12.9 1.5 0.41 10.3 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF164 PF02591.10 EMC99754.1 - 0.098 12.5 3.0 2.4 8.0 0.3 2.7 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-CCCH PF00642.19 EMC99754.1 - 0.43 10.3 9.2 0.026 14.2 2.0 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3295 PF11702.3 EMC99755.1 - 3.6e-128 428.7 38.2 4.6e-128 428.3 26.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EMC99755.1 - 1.2e-13 50.3 4.1 2.7e-11 42.8 1.7 2.6 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF1752) NOA36 PF06524.7 EMC99755.1 - 0.86 8.8 6.9 1.6 7.8 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein Myosin_tail_1 PF01576.14 EMC99758.1 - 1.4e-06 26.4 58.7 1.4e-06 26.4 40.7 4.3 2 1 2 4 4 4 1 Myosin tail RecR PF02132.10 EMC99758.1 - 0.17 11.3 1.4 15 5.1 0.0 3.6 3 0 0 3 3 3 0 RecR protein GAS PF13851.1 EMC99758.1 - 2.2 7.4 130.7 0.6 9.2 12.5 8.4 3 2 4 8 8 8 0 Growth-arrest specific micro-tubule binding zf-met PF12874.2 EMC99759.1 - 0.00025 21.1 1.0 0.00038 20.5 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC99759.1 - 0.0018 18.3 0.3 0.0025 17.9 0.2 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC99759.1 - 0.0076 16.3 0.0 0.0079 16.2 0.0 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF1677 PF07911.8 EMC99759.1 - 0.016 15.3 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) DUF3505 PF12013.3 EMC99759.1 - 0.046 13.9 0.1 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Peptidase_C2 PF00648.16 EMC99760.1 - 6.4e-58 196.0 1.5 5.7e-39 133.8 0.4 2.3 1 1 1 2 2 2 2 Calpain family cysteine protease VHS PF00790.14 EMC99762.1 - 9.8e-21 73.8 0.0 2.4e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EMC99762.1 - 1.8e-08 34.2 1.8 3.3e-08 33.4 0.3 2.0 2 0 0 2 2 2 1 GAT domain TFIIE-A_C-term PF11521.3 EMC99762.1 - 3.8 7.5 6.5 34 4.4 0.1 3.9 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha F-actin_cap_A PF01267.12 EMC99765.1 - 1.3e-79 267.0 0.2 1.5e-79 266.8 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Alph_Pro_TM PF09608.5 EMC99765.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) AAA_12 PF13087.1 EMC99766.1 - 1.1e-40 139.1 0.0 1.8e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMC99766.1 - 2e-26 93.0 0.0 4.9e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC99766.1 - 3.2e-08 33.2 0.1 1.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMC99766.1 - 8.4e-05 22.2 0.1 0.032 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMC99766.1 - 0.0001 21.7 0.2 0.00048 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC99766.1 - 0.0024 17.8 1.8 0.023 14.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain DUF2075 PF09848.4 EMC99766.1 - 0.0029 16.6 0.3 1.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 EMC99766.1 - 0.0039 17.3 0.0 0.025 14.7 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EMC99766.1 - 0.036 14.2 0.1 0.28 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain CHASE2 PF05226.6 EMC99766.1 - 0.065 12.4 0.1 11 5.0 0.0 2.3 2 0 0 2 2 2 0 CHASE2 domain AAA_5 PF07728.9 EMC99766.1 - 0.071 12.8 0.3 0.23 11.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NIF PF03031.13 EMC99767.1 - 1.3e-34 119.1 0.0 1.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Med25_VWA PF11265.3 EMC99767.1 - 0.14 11.2 0.1 1.9 7.4 0.2 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A Glyco_hydro_47 PF01532.15 EMC99768.1 - 1.8e-127 425.7 0.0 2.2e-127 425.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ribosomal_60s PF00428.14 EMC99768.1 - 2.7 8.4 5.2 6.5 7.2 3.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein CPDase PF07823.6 EMC99769.1 - 6.4e-27 94.3 0.1 7.3e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EMC99769.1 - 0.00037 20.2 0.3 0.039 13.6 0.1 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily UreD PF01774.12 EMC99769.1 - 0.095 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 UreD urease accessory protein Phage_T4_gp19 PF06841.7 EMC99769.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 TRP PF06011.7 EMC99770.1 - 4.6e-80 269.3 30.9 4.6e-79 266.0 21.4 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMC99770.1 - 1.7e-23 83.2 0.1 2.6e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 ML-like domain BNR PF02012.15 EMC99771.1 - 0.033 13.9 13.0 0.081 12.7 1.1 3.9 4 0 0 4 4 4 0 BNR/Asp-box repeat MFS_1 PF07690.11 EMC99772.1 - 1e-34 119.7 42.6 1e-34 119.7 29.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 EMC99772.1 - 4.1e-05 22.3 0.7 4.1e-05 22.3 0.5 2.9 2 1 1 3 3 3 1 LacY proton/sugar symporter DUF3149 PF11346.3 EMC99772.1 - 0.082 12.4 0.3 0.082 12.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) His_Phos_2 PF00328.17 EMC99773.1 - 5.5e-32 111.4 0.0 7.5e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HEAT PF02985.17 EMC99774.1 - 9.4e-21 71.9 8.0 1.3e-05 24.9 0.3 10.0 10 0 0 10 10 9 3 HEAT repeat HEAT_EZ PF13513.1 EMC99774.1 - 4.7e-17 61.9 15.7 4.9e-05 23.6 0.3 10.8 9 4 5 14 14 12 5 HEAT-like repeat HEAT_2 PF13646.1 EMC99774.1 - 3.1e-15 56.2 15.5 0.00038 20.6 0.2 8.1 6 3 3 9 9 8 4 HEAT repeats IBN_N PF03810.14 EMC99774.1 - 1.6e-11 43.9 2.8 1.7e-10 40.6 0.3 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EMC99774.1 - 2.4e-09 37.4 2.3 0.41 11.0 0.0 5.8 6 0 0 6 6 6 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EMC99774.1 - 3.7e-08 32.1 3.2 9.1e-05 20.9 0.0 3.8 3 1 0 3 3 3 2 Adaptin N terminal region UME PF08064.8 EMC99774.1 - 1.4e-07 31.4 0.1 0.038 13.9 0.0 5.2 4 1 1 5 5 5 1 UME (NUC010) domain Arm PF00514.18 EMC99774.1 - 1.7e-05 24.4 0.5 17 5.4 0.0 6.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat IFRD PF05004.8 EMC99774.1 - 0.00014 21.0 5.3 0.098 11.7 0.1 3.7 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.3 EMC99774.1 - 0.00015 20.6 7.7 0.0016 17.2 0.1 4.8 3 3 2 5 5 5 1 RNAPII transcription regulator C-terminal Cohesin_HEAT PF12765.2 EMC99774.1 - 0.00082 19.2 0.5 0.071 13.0 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.3 EMC99774.1 - 0.00087 18.7 0.1 8.8 5.6 0.0 4.7 4 1 2 6 6 6 1 CLASP N terminal Cnd3 PF12719.2 EMC99774.1 - 0.0013 17.8 5.2 1.3 7.9 0.0 3.7 3 1 1 4 4 4 2 Nuclear condensing complex subunits, C-term domain DUF1546 PF07571.8 EMC99774.1 - 0.0036 17.3 0.3 1.3 9.2 0.1 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1546) ParA PF10609.4 EMC99775.1 - 5.5e-33 112.6 0.1 1.1e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMC99775.1 - 2.4e-14 53.2 0.0 3.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMC99775.1 - 3.5e-09 36.7 0.0 1.3e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EMC99775.1 - 5.2e-05 22.4 0.1 0.0001 21.4 0.1 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EMC99775.1 - 0.0035 16.7 0.1 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EMC99775.1 - 0.0071 15.4 0.7 0.082 11.9 0.5 2.4 3 0 0 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 EMC99775.1 - 0.016 14.4 0.1 1.4 8.0 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 EMC99775.1 - 0.018 14.6 0.3 2 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Gly-zipper_OmpA PF13436.1 EMC99776.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 EMC99776.1 - 0.00034 20.2 10.8 0.00058 19.4 7.5 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 EMC99776.1 - 0.063 13.4 4.8 0.1 12.7 3.3 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 EMC99776.1 - 0.28 10.8 13.9 1.2 8.8 9.7 1.8 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EMC99776.1 - 7.2 6.2 15.2 31 4.1 10.6 1.9 1 1 0 1 1 1 0 YMGG-like Gly-zipper Epimerase PF01370.16 EMC99777.1 - 1.1e-08 34.8 0.7 7.9e-07 28.7 0.5 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC99777.1 - 5.7e-05 22.1 0.0 9.7e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMC99777.1 - 7.6e-05 22.7 0.2 0.00026 21.0 0.0 2.1 3 0 0 3 3 3 1 NADH(P)-binding NmrA PF05368.8 EMC99777.1 - 0.00033 19.9 0.3 0.001 18.3 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 EMC99777.1 - 0.00054 19.0 0.2 0.001 18.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EMC99777.1 - 0.00094 17.9 0.6 0.0082 14.8 0.4 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMC99777.1 - 0.015 15.5 0.0 0.043 14.1 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMC99777.1 - 0.02 15.3 0.1 0.13 12.7 0.0 2.4 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 EMC99778.1 - 9.9e-27 94.3 0.0 1.4e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMC99778.1 - 5.1e-19 67.8 0.0 1e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMC99778.1 - 1.3e-07 31.5 0.0 5.2e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMC99778.1 - 1.6e-06 27.2 0.4 6.8e-06 25.2 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMC99778.1 - 3.5e-06 27.0 0.0 0.00016 21.6 0.0 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC99778.1 - 0.00029 19.8 0.0 0.074 11.9 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC99778.1 - 0.013 14.4 0.1 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EMC99778.1 - 0.018 14.8 1.2 0.45 10.2 0.1 3.2 3 2 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EMC99778.1 - 0.022 13.8 0.2 0.18 10.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMC99778.1 - 0.032 14.6 0.0 0.93 9.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC99778.1 - 0.038 13.0 0.1 0.3 10.0 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EMC99778.1 - 0.047 12.7 0.3 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EMC99778.1 - 0.13 11.1 0.1 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 EMC99778.1 - 0.79 9.5 4.2 7.4 6.3 0.0 3.0 2 1 1 3 3 3 0 ThiF family ATG13 PF10033.4 EMC99779.1 - 2.4e-49 167.8 0.0 3.8e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 NmrA PF05368.8 EMC99780.1 - 7.7e-36 123.5 0.0 9.6e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMC99780.1 - 1.9e-12 47.5 0.0 2.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC99780.1 - 4e-06 26.4 0.1 5.6e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMC99780.1 - 1.8e-05 24.7 1.4 2.9e-05 24.0 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EMC99780.1 - 3.2e-05 23.8 0.1 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EMC99780.1 - 0.00096 17.9 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMC99780.1 - 0.0042 16.0 0.1 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EMC99780.1 - 0.006 16.2 0.4 0.011 15.3 0.3 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EMC99780.1 - 0.0076 16.6 0.2 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMC99780.1 - 0.015 15.1 0.1 0.038 13.8 0.1 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EMC99780.1 - 0.053 13.1 0.9 0.099 12.2 0.4 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EMC99780.1 - 0.057 13.7 0.3 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TSNR_N PF04705.7 EMC99782.1 - 0.0076 16.0 0.0 1.3 8.8 0.0 3.5 2 1 2 4 4 4 1 Thiostrepton-resistance methylase, N terminus DUF2508 PF10704.4 EMC99782.1 - 0.064 13.4 0.2 0.064 13.4 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) EAP30 PF04157.11 EMC99782.1 - 0.075 12.1 0.1 0.075 12.1 0.1 3.3 2 1 1 3 3 3 0 EAP30/Vps36 family ACR_tran PF00873.14 EMC99782.1 - 0.093 10.1 5.7 0.16 9.3 4.0 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Baculo_PEP_C PF04513.7 EMC99782.1 - 0.33 10.7 16.6 0.39 10.5 0.4 4.1 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EMC99782.1 - 1.2 7.4 9.4 0.16 10.3 2.7 1.9 1 1 1 2 2 2 0 AAA domain Prominin PF05478.6 EMC99782.1 - 3.1 5.1 8.2 2.1 5.7 2.2 2.1 2 0 0 2 2 2 0 Prominin CorA PF01544.13 EMC99782.1 - 6.1 5.7 10.4 5.4 5.9 1.3 3.3 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein PMSR PF01625.16 EMC99784.1 - 4.6e-60 202.0 0.1 5.7e-60 201.7 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Asp PF00026.18 EMC99786.1 - 8.2e-17 61.4 0.1 1.1e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Glycophorin_A PF01102.13 EMC99786.1 - 9.8e-05 22.1 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycophorin A VSP PF03302.8 EMC99786.1 - 0.03 12.9 1.6 0.042 12.4 1.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein PgaD PF13994.1 EMC99786.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein P12 PF12669.2 EMC99786.1 - 3.6 7.8 4.0 6.1 7.1 2.8 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family SH3_9 PF14604.1 EMC99788.1 - 8.6e-15 54.0 0.1 9.3e-15 53.9 0.1 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC99788.1 - 1.9e-13 49.5 0.0 2e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC99788.1 - 5.7e-08 32.1 0.0 6.2e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain DUF3253 PF11625.3 EMC99789.1 - 7.2e-25 86.6 0.1 8.4e-25 86.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) DUF2231 PF09990.4 EMC99790.1 - 7.7e-07 29.4 0.6 1.2e-06 28.8 0.4 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) Fungal_trans PF04082.13 EMC99791.1 - 1.4e-21 76.5 0.0 2.1e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC99791.1 - 3.3e-08 33.3 10.1 5.6e-08 32.5 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LEM PF03020.10 EMC99791.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 LEM domain CGI-121 PF08617.5 EMC99792.1 - 9.2e-46 155.4 0.0 1e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 BatA PF07584.6 EMC99793.1 - 0.076 13.2 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF1153 PF06627.6 EMC99795.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) NYAP_C PF15452.1 EMC99795.1 - 0.13 11.2 0.3 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Isochorismatase PF00857.15 EMC99796.1 - 2.2e-24 86.3 0.1 3.6e-24 85.6 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family Oxysterol_BP PF01237.13 EMC99800.1 - 1.7e-90 303.1 0.0 2.3e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Cys_Met_Meta_PP PF01053.15 EMC99801.1 - 7.1e-59 199.0 0.0 2.4e-58 197.2 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMC99801.1 - 0.0002 20.2 0.0 0.0004 19.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EMC99801.1 - 0.04 12.8 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Pro_isomerase PF00160.16 EMC99803.1 - 6e-42 143.4 0.8 9.6e-42 142.8 0.5 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 EMC99804.1 - 2.7e-48 162.9 0.7 3.8e-48 162.4 0.5 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EMC99804.1 - 0.00013 20.7 0.1 0.00018 20.3 0.0 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EMC99804.1 - 0.064 12.8 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF3542 PF12061.3 EMC99804.1 - 0.2 10.5 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) C2 PF00168.25 EMC99805.1 - 3.8e-62 206.1 5.1 5.2e-19 67.8 0.0 5.6 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EMC99805.1 - 0.073 13.2 0.2 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) SHQ1 PF04925.10 EMC99806.1 - 0.12 11.7 0.1 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 SHQ1 protein adh_short PF00106.20 EMC99807.1 - 2e-20 73.3 1.0 4e-20 72.3 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99807.1 - 2e-09 37.5 0.0 2.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99807.1 - 1.3e-08 34.7 0.1 1.9e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC99807.1 - 3.5e-05 23.8 0.0 6.8e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC99807.1 - 3.9e-05 23.1 0.3 8.6e-05 22.0 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EMC99807.1 - 0.013 14.5 0.1 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EMC99807.1 - 0.019 13.8 0.7 0.054 12.3 0.5 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FolB PF02152.13 EMC99811.1 - 2.4e-13 50.2 0.0 3.8e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase UDPGP PF01704.13 EMC99812.1 - 9.4e-183 607.4 0.3 1.1e-182 607.1 0.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Acyl-CoA_dh_1 PF00441.19 EMC99813.1 - 1.2e-33 116.3 1.3 1.8e-33 115.7 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC99813.1 - 5.1e-21 75.3 0.0 1.8e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMC99813.1 - 9.7e-16 57.0 0.0 2.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC99813.1 - 3.4e-12 46.7 0.3 6.1e-12 45.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.15 EMC99813.1 - 0.038 14.1 0.5 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase CoA_transf_3 PF02515.12 EMC99814.1 - 8.5e-64 214.3 0.1 1.2e-63 213.8 0.1 1.2 1 0 0 1 1 1 1 CoA-transferase family III Pribosyltran PF00156.22 EMC99816.1 - 1.2e-15 57.2 0.0 1.7e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMC99816.1 - 0.014 14.5 0.0 0.03 13.5 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Lactamase_B PF00753.22 EMC99817.1 - 2.7e-11 43.5 2.7 3.7e-11 43.0 1.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC99817.1 - 3.2e-05 23.5 0.2 3.9e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_6 PF12697.2 EMC99818.1 - 3.3e-11 43.5 0.0 3.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC99818.1 - 2.3e-06 27.3 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC99818.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family EBV-NA1 PF02905.9 EMC99818.1 - 0.098 12.1 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain ING PF12998.2 EMC99819.1 - 2.9e-17 62.8 0.1 4.2e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMC99819.1 - 9.4e-09 34.8 10.6 1.8e-08 33.9 7.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EMC99819.1 - 0.00095 19.2 0.8 0.0023 18.0 0.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain TFIIA PF03153.8 EMC99819.1 - 0.0093 15.8 7.4 0.014 15.3 5.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Arfaptin PF06456.8 EMC99819.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Arfaptin-like domain Hist_deacetyl PF00850.14 EMC99820.1 - 2.7e-71 240.4 0.1 3.6e-71 239.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain AAA PF00004.24 EMC99821.1 - 1.4e-17 64.1 0.0 2.9e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC99821.1 - 0.00022 21.3 2.3 0.0025 17.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EMC99821.1 - 0.00077 20.2 0.0 0.0024 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC99821.1 - 0.0023 18.2 0.0 0.026 14.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EMC99821.1 - 0.0027 16.7 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMC99821.1 - 0.0038 16.9 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EMC99821.1 - 0.0084 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EMC99821.1 - 0.018 14.9 0.0 0.067 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMC99821.1 - 0.032 14.2 0.4 0.15 12.0 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 EMC99821.1 - 0.043 12.9 0.3 0.55 9.3 0.0 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI bZIP_1 PF00170.16 EMC99822.1 - 1.5e-09 37.6 8.6 2.4e-09 37.0 6.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC99822.1 - 8e-07 28.7 13.4 1.1e-06 28.3 9.3 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC99822.1 - 0.00011 22.4 3.8 0.00015 21.9 2.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Glyco_hydro_16 PF00722.16 EMC99824.1 - 2.8e-41 140.8 7.2 2.8e-41 140.8 5.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EMC99824.1 - 0.028 14.4 14.8 0.069 13.1 10.3 1.6 1 0 0 1 1 1 0 Chitin recognition protein adh_short PF00106.20 EMC99825.1 - 3.2e-18 66.1 0.3 6.3e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99825.1 - 4.3e-07 29.9 0.1 6.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99825.1 - 1.3e-06 28.2 0.2 2.2e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Laminin_II PF06009.7 EMC99827.1 - 0.029 14.1 1.7 5.5 6.7 0.1 2.6 1 1 1 2 2 2 0 Laminin Domain II Rogdi_lz PF10259.4 EMC99827.1 - 0.051 12.6 4.3 0.12 11.4 0.4 2.1 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein DUF948 PF06103.6 EMC99827.1 - 0.11 12.4 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.13 EMC99827.1 - 0.47 9.4 4.2 0.65 8.9 2.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4600 PF15372.1 EMC99827.1 - 1.9 8.6 7.0 3.1 8.0 3.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) CENP-B_dimeris PF09026.5 EMC99828.1 - 0.048 13.8 0.1 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HMG-CoA_red PF00368.13 EMC99829.1 - 1.4e-158 527.4 3.6 1.8e-158 527.0 2.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EMC99829.1 - 1.3e-35 122.3 0.0 2.5e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EMC99829.1 - 9.5e-13 47.8 2.3 2.7e-12 46.3 1.6 1.8 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EMC99829.1 - 9.4e-07 27.1 1.4 1.5e-06 26.4 1.0 1.2 1 0 0 1 1 1 1 Patched family DUF2304 PF10066.4 EMC99829.1 - 0.089 12.6 1.5 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) MBF1 PF08523.5 EMC99830.1 - 0.015 15.2 0.7 0.019 14.9 0.5 1.1 1 0 0 1 1 1 0 Multiprotein bridging factor 1 GIT_SHD PF08518.6 EMC99831.1 - 1.6e-21 75.3 7.7 4.1e-13 48.4 2.0 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ATG16 PF08614.6 EMC99831.1 - 0.0002 21.2 46.7 0.038 13.8 15.3 3.7 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Filament PF00038.16 EMC99831.1 - 0.0014 18.2 16.6 0.0014 18.2 11.5 3.2 1 1 2 3 3 3 2 Intermediate filament protein DUF904 PF06005.7 EMC99831.1 - 0.0023 18.2 0.4 0.0023 18.2 0.3 4.8 2 1 1 3 3 2 1 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 EMC99831.1 - 0.005 16.5 21.6 0.005 16.5 15.0 3.1 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EMC99831.1 - 0.01 15.0 2.7 0.62 9.1 1.0 2.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein MAD PF05557.8 EMC99831.1 - 0.013 13.6 34.9 0.021 12.9 24.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein THP2 PF09432.5 EMC99831.1 - 0.15 11.8 13.2 0.056 13.3 5.3 2.7 1 1 1 2 2 2 0 Tho complex subunit THP2 IncA PF04156.9 EMC99831.1 - 0.26 10.8 52.3 12 5.4 14.4 2.9 1 1 1 2 2 2 0 IncA protein Macoilin PF09726.4 EMC99831.1 - 1.2 7.2 39.0 0.28 9.4 20.5 2.4 1 1 1 2 2 2 0 Transmembrane protein DUF3584 PF12128.3 EMC99831.1 - 1.5 6.0 44.0 2.2 5.4 30.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.6 EMC99831.1 - 3.6 7.5 9.0 15 5.6 0.1 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 EMC99831.1 - 5.5 6.8 37.8 0.16 11.7 0.7 5.0 3 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF3605 PF12239.3 EMC99832.1 - 3.9e-54 182.7 0.6 5e-54 182.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Transp_cyt_pur PF02133.10 EMC99833.1 - 9.8e-44 149.5 44.3 1.2e-43 149.2 30.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pro_dh PF01619.13 EMC99835.1 - 1.6e-33 116.0 1.0 3.1e-33 115.1 0.7 1.4 1 1 0 1 1 1 1 Proline dehydrogenase zf-CGNR PF11706.3 EMC99837.1 - 0.19 11.2 3.3 0.16 11.5 0.5 2.3 2 0 0 2 2 2 0 CGNR zinc finger SprT-like PF10263.4 EMC99838.1 - 0.00022 20.9 0.4 0.00087 18.9 0.3 1.9 1 1 0 1 1 1 1 SprT-like family WLM PF08325.5 EMC99838.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 WLM domain DUF4344 PF14247.1 EMC99838.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Peptidase_M50B PF13398.1 EMC99838.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Sperm_Ag_HE2 PF05324.8 EMC99838.1 - 0.12 12.2 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Sperm antigen HE2 TFR_dimer PF04253.10 EMC99839.1 - 1.2e-19 70.1 0.0 2.2e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMC99839.1 - 5.2e-14 52.3 0.9 3.1e-13 49.8 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EMC99839.1 - 6.1e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EMC99839.1 - 0.038 13.2 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Nicastrin adh_short PF00106.20 EMC99840.1 - 1.2e-26 93.5 0.9 1.5e-26 93.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC99840.1 - 1.4e-26 93.7 0.3 1.6e-26 93.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC99840.1 - 1.8e-14 53.8 0.5 2.4e-14 53.4 0.3 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 EMC99840.1 - 0.026 14.1 0.4 0.052 13.1 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus RELT PF12606.3 EMC99840.1 - 0.036 13.2 0.4 0.064 12.4 0.2 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF95 PF01944.12 EMC99843.1 - 0.00055 19.6 0.6 0.00057 19.5 0.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF95 Scs3p PF10261.4 EMC99843.1 - 0.062 12.3 0.2 0.067 12.2 0.1 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM SNF2_N PF00176.18 EMC99844.1 - 2.4e-47 161.2 0.0 3.6e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EMC99844.1 - 4.1e-20 71.4 2.1 9.5e-20 70.2 1.5 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EMC99844.1 - 6.3e-14 51.6 0.0 2.7e-12 46.3 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC99844.1 - 0.0041 16.9 0.2 0.04 13.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SEC-C PF02810.10 EMC99844.1 - 0.016 14.7 4.8 0.03 13.8 3.3 1.5 1 0 0 1 1 1 0 SEC-C motif RNase_PH PF01138.16 EMC99845.1 - 4.5e-35 120.8 0.1 7.5e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Cytochrom_B561 PF03188.11 EMC99846.1 - 1.7e-09 37.6 6.7 3.2e-09 36.7 4.6 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EMC99846.1 - 3.9e-08 33.2 0.0 8.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 EMC99846.1 - 0.0033 16.9 3.9 0.0033 16.9 2.7 2.5 2 1 2 4 4 4 1 Domain of unknown function (DUF2427) Cytochrom_B_N PF00033.14 EMC99846.1 - 0.0058 16.0 4.6 0.075 12.3 3.2 2.6 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB SdpI PF13630.1 EMC99846.1 - 0.016 14.9 1.7 0.016 14.9 1.2 3.7 2 1 2 4 4 4 0 SdpI/YhfL protein family DUF2306 PF10067.4 EMC99846.1 - 0.087 12.9 0.4 0.087 12.9 0.3 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) YfhO PF09586.5 EMC99846.1 - 0.15 10.0 2.2 0.26 9.2 1.5 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO EphA2_TM PF14575.1 EMC99846.1 - 0.18 12.2 0.4 0.83 10.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1183 PF06682.7 EMC99846.1 - 8.6 5.8 7.3 54 3.2 5.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) His_Phos_2 PF00328.17 EMC99847.1 - 4.2e-40 138.1 0.0 6.2e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Synaptobrevin PF00957.16 EMC99848.1 - 0.071 12.7 0.1 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 Synaptobrevin RskA PF10099.4 EMC99848.1 - 0.095 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2077 PF09850.4 EMC99848.1 - 0.11 11.8 0.2 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF2116 PF09889.4 EMC99848.1 - 0.15 11.8 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ribosomal_S14 PF00253.16 EMC99849.1 - 2.6e-17 61.9 1.1 2.9e-17 61.7 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-CCCH PF00642.19 EMC99850.1 - 4.3e-09 35.8 14.3 2.8e-07 30.0 1.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EMC99850.1 - 8.8e-06 25.4 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC99850.1 - 0.00019 20.9 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC99850.1 - 0.046 13.7 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 EMC99850.1 - 0.69 9.7 4.3 0.87 9.4 0.0 2.4 2 1 0 2 2 2 0 Scrapie-responsive protein 1 FAD_binding_7 PF03441.9 EMC99851.1 - 3.3e-98 328.3 0.0 6.2e-98 327.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMC99851.1 - 6.5e-40 136.5 0.0 1.1e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 EMC99851.1 - 0.079 13.1 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family DZR PF12773.2 EMC99855.1 - 0.059 13.1 3.2 0.81 9.5 2.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2769 PF10967.3 EMC99855.1 - 0.35 11.1 3.2 0.45 10.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) zf-ribbon_3 PF13248.1 EMC99855.1 - 1.2 8.4 4.3 3.9 6.8 3.0 2.0 1 1 0 1 1 1 0 zinc-ribbon domain RNA_pol_Rpc34 PF05158.7 EMC99857.1 - 1.4e-59 201.9 0.0 1.8e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EMC99857.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC TrmB PF01978.14 EMC99857.1 - 0.044 13.4 0.2 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Slx4 PF09494.5 EMC99859.1 - 2.7e-13 49.4 1.3 2.6e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 Slx4 endonuclease ABC_tran PF00005.22 EMC99860.1 - 7.2e-47 159.1 0.0 4.9e-29 101.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMC99860.1 - 8e-33 114.0 27.0 1.2e-16 60.9 8.7 3.7 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EMC99860.1 - 1.4e-13 50.6 1.6 6.5e-06 25.5 0.1 4.2 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC99860.1 - 1.6e-10 41.4 0.0 0.1 12.5 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EMC99860.1 - 2.6e-08 33.2 0.8 0.00013 21.4 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EMC99860.1 - 5.4e-08 33.3 0.1 0.00096 19.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC99860.1 - 1.4e-06 28.4 0.1 0.053 13.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMC99860.1 - 8.2e-06 25.3 0.1 0.0058 16.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EMC99860.1 - 2.2e-05 23.4 0.1 0.16 10.8 0.2 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EMC99860.1 - 2.9e-05 24.1 0.5 0.11 12.4 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMC99860.1 - 9.8e-05 21.9 0.0 0.058 12.8 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 EMC99860.1 - 0.0024 17.7 0.0 2.2 8.2 0.0 3.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EMC99860.1 - 0.0026 17.6 0.4 0.0055 16.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 DUF258 PF03193.11 EMC99860.1 - 0.0046 16.1 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EMC99860.1 - 0.0049 17.3 0.0 2.4 8.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EMC99860.1 - 0.018 14.9 0.1 0.69 9.8 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.4 EMC99860.1 - 0.028 13.0 0.8 0.11 11.1 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.14 EMC99860.1 - 0.029 13.8 0.4 5.8 6.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EMC99860.1 - 0.03 13.7 1.7 0.41 10.0 0.1 2.8 4 0 0 4 4 2 0 AAA-like domain AAA_18 PF13238.1 EMC99860.1 - 0.036 14.3 0.0 6.9 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EMC99860.1 - 0.044 13.2 1.8 11 5.5 1.3 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.1 EMC99860.1 - 0.049 13.4 0.2 17 5.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMC99860.1 - 0.051 14.4 0.0 1.8 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMC99860.1 - 0.051 13.3 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 EMC99860.1 - 0.064 12.9 0.1 2.8 7.5 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase IstB_IS21 PF01695.12 EMC99860.1 - 0.065 12.6 0.7 3.2 7.1 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EMC99860.1 - 0.075 12.5 0.3 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EMC99860.1 - 0.09 12.4 0.1 7.1 6.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 EMC99860.1 - 0.098 12.1 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 EMC99860.1 - 0.1 11.2 0.5 2 6.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 EMC99860.1 - 0.19 10.7 0.1 9.6 5.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 EMC99860.1 - 0.21 11.0 0.5 1.4 8.3 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 EMC99860.1 - 0.23 10.4 0.0 0.65 8.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.22 EMC99860.1 - 0.25 10.7 0.0 6 6.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Acetyltransf_1 PF00583.19 EMC99863.1 - 0.00036 20.5 0.2 0.0013 18.7 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC99863.1 - 0.0036 17.4 0.0 0.0081 16.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC99863.1 - 0.031 14.4 0.1 0.067 13.3 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ssu72 PF04722.8 EMC99864.1 - 2.4e-81 271.7 0.0 2.9e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Hyccin PF09790.4 EMC99864.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Hyccin FYVE PF01363.16 EMC99865.1 - 5.6e-15 54.9 1.1 5.6e-15 54.9 0.8 3.4 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EMC99865.1 - 1.3e-09 37.6 17.8 7.8e-09 35.2 2.5 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EMC99865.1 - 0.00044 19.8 1.5 0.00044 19.8 1.0 4.0 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EMC99865.1 - 0.00078 18.8 6.2 0.26 10.7 0.1 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-rbx1 PF12678.2 EMC99865.1 - 0.0046 17.0 12.3 0.009 16.0 2.4 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger RINGv PF12906.2 EMC99865.1 - 0.0093 15.9 4.6 0.0093 15.9 3.2 3.2 4 0 0 4 4 4 1 RING-variant domain FANCL_C PF11793.3 EMC99865.1 - 0.019 14.9 3.5 0.019 14.9 2.4 2.9 3 0 0 3 3 3 0 FANCL C-terminal domain DZR PF12773.2 EMC99865.1 - 0.094 12.5 8.6 0.7 9.7 0.2 3.3 3 0 0 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EMC99865.1 - 0.13 11.9 14.3 0.57 9.9 1.5 3.8 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EMC99865.1 - 4.2 7.0 13.7 13 5.4 3.1 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Aldedh PF00171.17 EMC99866.1 - 1.5e-131 438.9 0.9 1.9e-131 438.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC99866.1 - 0.00016 20.5 0.0 0.00034 19.4 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EMC99866.1 - 0.00033 19.9 0.0 0.00048 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Fungal_trans PF04082.13 EMC99867.1 - 7.8e-15 54.4 0.0 1.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC99867.1 - 1.8e-05 24.5 13.5 3.1e-05 23.8 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1793 PF08760.6 EMC99870.1 - 3.7e-63 212.4 0.1 9.7e-63 211.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) RibD_C PF01872.12 EMC99871.1 - 5.3e-31 107.7 0.0 7.7e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain GFA PF04828.9 EMC99872.1 - 2.1e-18 66.0 0.1 2.1e-18 66.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 EMC99872.1 - 0.54 9.8 6.4 0.15 11.5 1.6 1.9 2 0 0 2 2 2 0 CSL zinc finger zf-C2H2 PF00096.21 EMC99873.1 - 6.7e-06 26.1 27.6 0.019 15.2 0.2 6.0 4 2 1 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC99873.1 - 1.7e-05 24.8 26.6 0.11 12.9 0.6 5.9 4 1 1 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC99873.1 - 0.0028 17.7 19.7 0.02 15.0 0.4 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC99873.1 - 2.7 8.3 11.6 12 6.3 0.2 4.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMC99873.1 - 4.5 7.7 17.0 3.5 8.0 0.2 5.3 5 0 0 5 5 5 0 Zinc-finger double domain SLT PF01464.15 EMC99875.1 - 3.4e-05 23.3 0.3 5.4e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain DUF2413 PF10310.4 EMC99878.1 - 1.2e-130 436.3 0.0 1.3e-130 436.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EMC99878.1 - 0.013 15.4 1.5 0.032 14.2 0.3 2.1 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain ADH_zinc_N PF00107.21 EMC99879.1 - 2.6e-13 49.6 0.3 4.9e-13 48.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC99879.1 - 2.5e-10 40.0 0.5 7.3e-10 38.5 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3405 PF11885.3 EMC99880.1 - 5e-179 595.6 18.7 6.4e-178 592.0 10.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3405) Cortex-I_coil PF09304.5 EMC99881.1 - 0.00026 21.0 4.4 0.00026 21.0 3.1 2.8 2 1 1 3 3 3 1 Cortexillin I, coiled coil DUF812 PF05667.6 EMC99881.1 - 0.0026 16.3 1.8 0.0041 15.6 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_13 PF13166.1 EMC99881.1 - 0.02 13.3 0.6 0.028 12.8 0.4 1.1 1 0 0 1 1 1 0 AAA domain FlxA PF14282.1 EMC99881.1 - 0.026 14.4 1.0 0.33 10.9 0.2 2.7 2 0 0 2 2 2 0 FlxA-like protein Tropomyosin_1 PF12718.2 EMC99881.1 - 0.12 12.2 15.1 0.61 9.9 10.4 2.1 1 1 0 1 1 1 0 Tropomyosin like Laminin_II PF06009.7 EMC99881.1 - 0.13 11.9 4.9 0.12 12.1 0.9 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF4407 PF14362.1 EMC99881.1 - 0.16 10.9 4.4 0.26 10.2 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cob_adeno_trans PF01923.13 EMC99881.1 - 0.27 11.0 3.7 0.54 10.0 2.6 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IncA PF04156.9 EMC99881.1 - 0.27 10.7 7.2 0.76 9.3 5.0 1.8 1 0 0 1 1 1 0 IncA protein Filament PF00038.16 EMC99881.1 - 0.67 9.3 16.3 2 7.7 2.9 2.2 1 1 1 2 2 2 0 Intermediate filament protein Atg14 PF10186.4 EMC99881.1 - 0.81 8.5 6.9 0.72 8.7 3.7 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EMC99881.1 - 1.4 6.6 2.9 2.1 6.1 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4201 PF13870.1 EMC99881.1 - 2.2 7.6 7.6 4.7 6.6 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 EMC99881.1 - 2.6 7.8 7.6 1.3 8.8 0.9 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EMC99881.1 - 3 8.2 5.9 31 5.0 0.1 2.8 2 1 0 2 2 2 0 SlyX DivIC PF04977.10 EMC99881.1 - 3.4 7.2 9.7 0.59 9.6 1.5 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 EMC99881.1 - 4.1 7.8 14.6 3.1 8.2 3.1 3.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 EMC99881.1 - 8.9 6.1 11.2 0.73 9.7 1.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Gly-zipper_Omp PF13488.1 EMC99883.1 - 2.8e-05 23.6 0.9 6e-05 22.5 0.6 1.5 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.10 EMC99883.1 - 9.3e-05 22.0 5.6 0.0002 20.9 3.9 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EMC99883.1 - 0.0016 17.9 5.9 0.0034 16.8 4.1 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF3225 PF11533.3 EMC99883.1 - 0.014 15.0 1.1 0.039 13.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) Gly-zipper_OmpA PF13436.1 EMC99883.1 - 0.026 14.1 0.0 0.067 12.8 0.0 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Transgly_assoc PF04226.8 EMC99883.1 - 2.7 8.1 7.6 3 7.9 3.7 1.9 1 1 1 2 2 2 0 Transglycosylase associated protein IMPDH PF00478.20 EMC99884.1 - 6.1e-128 426.6 0.0 6e-126 420.0 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EMC99884.1 - 1.2e-18 66.6 0.0 2.7e-09 36.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EMC99884.1 - 7.7e-09 34.8 0.8 1.6e-08 33.7 0.5 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EMC99884.1 - 5.5e-07 29.0 3.5 2.2e-05 23.7 2.1 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 EMC99884.1 - 0.00047 19.5 0.8 0.011 14.9 0.1 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EMC99884.1 - 0.035 13.1 0.7 0.064 12.3 0.5 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EMC99884.1 - 0.057 12.3 0.2 0.14 11.1 0.2 1.6 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF1273 PF06908.6 EMC99884.1 - 0.21 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Myb_DNA-bind_6 PF13921.1 EMC99887.1 - 7.4e-09 35.5 0.1 1.6e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMC99887.1 - 0.00069 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SOG2 PF10428.4 EMC99887.1 - 8.8 4.8 8.8 13 4.2 6.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Myb_DNA-binding PF00249.26 EMC99889.1 - 1.7e-11 44.0 0.7 8e-08 32.2 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC99889.1 - 1.2e-09 38.0 0.7 4.5e-06 26.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF498 PF04430.9 EMC99890.1 - 9.1e-28 96.0 0.0 2.7e-27 94.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) STAT1_TAZ2bind PF12162.3 EMC99890.1 - 0.47 9.9 1.7 0.92 8.9 1.2 1.5 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain PROCN PF08083.6 EMC99892.1 - 1.3e-222 738.6 6.9 2.1e-222 737.8 4.8 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EMC99892.1 - 2.9e-126 419.4 1.6 5e-126 418.6 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EMC99892.1 - 2.4e-93 309.7 1.0 5.2e-93 308.7 0.7 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EMC99892.1 - 1.3e-76 255.3 2.9 1.5e-76 255.1 0.9 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EMC99892.1 - 1.2e-66 222.4 0.1 2.4e-66 221.4 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EMC99892.1 - 2.7e-44 148.9 0.4 6.9e-44 147.6 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EMC99892.1 - 2.2e-36 124.3 0.0 7.2e-36 122.6 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain DUF3753 PF12575.3 EMC99892.1 - 0.077 12.7 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Ribosomal_L34e PF01199.13 EMC99893.1 - 2.5e-34 117.3 5.1 3.6e-34 116.8 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e zf-ribbon_3 PF13248.1 EMC99893.1 - 0.12 11.6 2.6 0.31 10.2 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 EMC99893.1 - 0.82 9.9 4.6 0.14 12.4 0.3 1.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Bax1-I PF01027.15 EMC99895.1 - 1.4e-28 99.9 11.4 2e-28 99.3 7.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.11 EMC99896.1 - 1.1e-15 57.2 35.4 2.6e-11 42.8 13.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Asn_synthase PF00733.16 EMC99897.1 - 2.6e-55 187.6 0.0 3.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMC99897.1 - 5.2e-33 113.4 0.0 1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMC99897.1 - 4.3e-31 107.6 0.0 1.3e-30 106.0 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EMC99897.1 - 0.0014 17.8 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EMC99897.1 - 0.0051 15.5 0.0 0.16 10.6 0.0 2.4 2 1 1 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EMC99897.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD synthase DUF3683 PF12447.3 EMC99897.1 - 0.11 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) tRNA_Me_trans PF03054.11 EMC99897.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DUF2427 PF10348.4 EMC99902.1 - 0.068 12.7 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Zn_clus PF00172.13 EMC99903.1 - 6e-07 29.2 6.7 1.3e-06 28.1 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMC99903.1 - 6.6e-07 28.4 0.6 1.2e-06 27.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3648 PF12364.3 EMC99903.1 - 0.089 12.7 0.1 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3648) DUF796 PF05638.7 EMC99904.1 - 7.9e-07 29.1 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF796) PTS_EIIB PF00367.15 EMC99904.1 - 0.16 11.2 0.1 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB Fungal_trans PF04082.13 EMC99905.1 - 1.2e-20 73.5 0.2 2e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMC99905.1 - 1.2e-08 34.6 11.4 2.5e-08 33.7 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EMC99906.1 - 0.039 14.3 3.4 2.7 8.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC99906.1 - 0.15 12.1 1.3 0.39 10.8 0.7 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Aldose_epim PF01263.15 EMC99907.1 - 1.5e-52 178.5 0.9 1.9e-52 178.2 0.6 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_7 PF00840.15 EMC99908.1 - 8e-198 657.1 25.7 1.2e-197 656.5 17.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EMC99908.1 - 8.4e-09 34.9 7.0 8.4e-09 34.9 4.8 6.3 5 1 1 6 6 6 1 Fungal cellulose binding domain Cu-oxidase_3 PF07732.10 EMC99909.1 - 2.8e-44 149.6 0.4 2.8e-44 149.6 0.3 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC99909.1 - 1.9e-32 111.6 6.6 1.5e-26 92.5 1.7 4.3 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EMC99909.1 - 1.5e-31 109.4 0.1 9e-30 103.6 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Toxin_59 PF15537.1 EMC99909.1 - 0.12 12.4 0.2 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative toxin 59 RRM_1 PF00076.17 EMC99912.1 - 6.7e-14 51.2 0.0 1.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC99912.1 - 7.3e-10 38.6 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC99912.1 - 1.1e-06 28.3 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tmemb_cc2 PF10267.4 EMC99912.1 - 0.019 13.5 0.0 0.024 13.2 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2088 PF09861.4 EMC99912.1 - 0.028 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) RRM_3 PF08777.6 EMC99912.1 - 0.036 13.8 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif HTH_IclR PF09339.5 EMC99915.1 - 0.41 10.2 4.0 0.29 10.7 1.5 1.6 1 1 0 1 1 1 0 IclR helix-turn-helix domain Hist_deacetyl PF00850.14 EMC99916.1 - 6.4e-78 262.1 0.4 1.3e-77 261.1 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.16 EMC99917.1 - 2.9e-34 117.2 0.0 5.2e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMC99917.1 - 3.5e-26 91.5 0.7 3.5e-26 91.5 0.5 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EMC99917.1 - 7.7e-09 35.0 0.0 1.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Fringe PF02434.11 EMC99918.1 - 1.8e-06 27.3 0.2 8e-05 21.9 0.1 2.8 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.21 EMC99918.1 - 0.0005 19.7 0.3 0.0011 18.6 0.2 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EMC99918.1 - 0.0081 15.8 1.7 0.021 14.5 1.2 1.7 1 0 0 1 1 1 1 PAN domain DUF3106 PF11304.3 EMC99918.1 - 4.7 7.6 10.9 0.24 11.8 1.5 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3106) Pkinase PF00069.20 EMC99919.1 - 4.1e-68 229.3 0.0 6.3e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC99919.1 - 4.6e-32 111.1 0.0 8.2e-31 107.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC99919.1 - 0.003 16.5 0.4 1.5 7.6 0.0 2.8 2 0 0 2 2 2 2 Kinase-like DUF336 PF03928.9 EMC99920.1 - 9.5e-28 96.6 0.0 1.1e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) p450 PF00067.17 EMC99922.1 - 1.9e-31 109.1 0.0 2.6e-31 108.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EMC99923.1 - 2e-08 34.0 11.6 3.1e-08 33.3 8.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMC99923.1 - 4.5e-06 25.5 0.7 5.9e-06 25.1 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EMC99924.1 - 1.6e-41 142.2 2.3 1.6e-41 142.2 1.6 1.5 2 0 0 2 2 2 1 RTA1 like protein PcrB PF01884.12 EMC99924.1 - 0.1 11.8 0.1 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 PcrB family Anp1 PF03452.9 EMC99925.1 - 2.7e-23 82.4 0.1 2e-22 79.6 0.1 2.1 1 1 0 1 1 1 1 Anp1 NTP_transf_3 PF12804.2 EMC99925.1 - 0.0087 16.1 0.1 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DAO PF01266.19 EMC99926.1 - 6.4e-20 71.3 0.7 3e-19 69.1 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC99926.1 - 2.8e-05 24.0 0.8 0.0025 17.8 0.1 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC99926.1 - 0.0016 18.3 0.1 0.041 13.7 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMC99926.1 - 0.0023 17.9 0.3 0.0089 16.0 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.1 EMC99926.1 - 0.0023 17.7 0.2 0.008 15.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMC99926.1 - 0.0059 16.9 0.3 0.2 12.0 0.2 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase C1_1 PF00130.17 EMC99926.1 - 0.0073 16.0 6.2 0.02 14.6 4.3 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EMC99926.1 - 0.0088 16.0 3.7 0.029 14.3 2.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAD_binding_3 PF01494.14 EMC99926.1 - 0.024 13.6 0.3 0.43 9.5 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EMC99926.1 - 0.046 13.7 0.0 0.89 9.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FYVE PF01363.16 EMC99926.1 - 0.047 13.5 6.1 0.16 11.8 4.2 1.9 1 0 0 1 1 1 0 FYVE zinc finger K_oxygenase PF13434.1 EMC99926.1 - 0.055 12.3 0.4 0.4 9.5 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.9 EMC99926.1 - 0.078 12.3 0.1 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-B_box PF00643.19 EMC99926.1 - 0.5 10.3 11.5 0.1 12.5 4.9 2.1 2 0 0 2 2 2 0 B-box zinc finger p450 PF00067.17 EMC99927.1 - 6.1e-79 265.6 0.0 6e-78 262.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ADIP PF11559.3 EMC99928.1 - 0.00043 20.2 12.8 0.0015 18.4 7.6 2.4 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EMC99928.1 - 0.00089 18.0 4.8 0.0017 17.0 3.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 EMC99928.1 - 0.002 17.7 12.8 0.002 17.7 6.3 2.6 2 1 1 3 3 3 1 IncA protein EzrA PF06160.7 EMC99928.1 - 0.0027 15.9 3.0 0.0044 15.2 2.1 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA AAA_13 PF13166.1 EMC99928.1 - 0.0028 16.1 3.5 0.0043 15.5 2.4 1.2 1 0 0 1 1 1 1 AAA domain TBPIP PF07106.8 EMC99928.1 - 0.003 17.1 3.6 0.0073 15.8 2.5 1.6 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cast PF10174.4 EMC99928.1 - 0.0039 15.3 4.5 0.0061 14.6 3.1 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Fib_alpha PF08702.5 EMC99928.1 - 0.0045 17.1 1.1 0.0045 17.1 0.8 2.3 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EMC99928.1 - 0.0046 16.8 10.1 0.005 16.6 5.8 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Striatin PF08232.7 EMC99928.1 - 0.0083 16.4 1.3 0.023 15.0 0.9 1.8 1 0 0 1 1 1 1 Striatin family COG2 PF06148.6 EMC99928.1 - 0.0087 15.9 3.3 0.027 14.3 2.1 2.0 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.16 EMC99928.1 - 0.01 15.3 6.4 0.02 14.3 4.5 1.5 1 0 0 1 1 1 1 Intermediate filament protein Macoilin PF09726.4 EMC99928.1 - 0.017 13.4 7.4 0.025 12.8 5.2 1.2 1 0 0 1 1 1 0 Transmembrane protein PhageMin_Tail PF10145.4 EMC99928.1 - 0.017 14.7 0.0 0.12 12.0 0.0 2.0 1 1 0 1 1 1 0 Phage-related minor tail protein NPV_P10 PF05531.7 EMC99928.1 - 0.018 15.2 1.5 0.089 13.0 1.0 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 EMC99928.1 - 0.021 12.1 8.3 0.031 11.6 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliJ PF02050.11 EMC99928.1 - 0.027 14.5 13.5 2 8.5 8.1 3.2 2 1 1 3 3 3 0 Flagellar FliJ protein Bacillus_HBL PF05791.6 EMC99928.1 - 0.034 13.5 2.6 0.057 12.7 1.8 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Gp58 PF07902.6 EMC99928.1 - 0.038 12.2 1.8 0.066 11.4 1.2 1.3 1 0 0 1 1 1 0 gp58-like protein TPR_12 PF13424.1 EMC99928.1 - 0.05 13.5 7.5 0.16 11.9 2.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LOH1CR12 PF10158.4 EMC99928.1 - 0.066 12.9 2.2 0.29 10.9 1.6 2.0 1 1 0 2 2 1 0 Tumour suppressor protein DUF2570 PF10828.3 EMC99928.1 - 0.067 12.8 6.1 0.67 9.5 4.8 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF2570) TPR_MLP1_2 PF07926.7 EMC99928.1 - 0.067 12.9 7.8 0.17 11.6 5.4 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HOOK PF05622.7 EMC99928.1 - 0.067 10.9 7.2 0.096 10.4 5.0 1.2 1 0 0 1 1 1 0 HOOK protein CENP-F_leu_zip PF10473.4 EMC99928.1 - 0.07 12.9 6.5 0.12 12.2 4.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PhosphMutase PF10143.4 EMC99928.1 - 0.085 12.4 0.4 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Atg14 PF10186.4 EMC99928.1 - 0.16 10.8 8.7 0.35 9.7 6.0 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 EMC99928.1 - 0.21 11.3 7.9 0.37 10.5 4.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 EMC99928.1 - 0.27 9.5 1.9 0.44 8.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1515 PF07439.6 EMC99928.1 - 0.34 10.7 1.4 0.66 9.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4407 PF14362.1 EMC99928.1 - 0.48 9.3 5.7 0.53 9.1 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.8 EMC99928.1 - 0.57 10.9 4.8 0.79 10.4 2.3 2.0 2 0 0 2 2 1 0 Occludin homology domain BLOC1_2 PF10046.4 EMC99928.1 - 0.72 10.0 4.0 4.1 7.5 1.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Kinetocho_Slk19 PF12709.2 EMC99928.1 - 1.3 9.1 6.5 6.5 6.9 0.5 2.8 1 1 1 2 2 2 0 Central kinetochore-associated DivIVA PF05103.8 EMC99928.1 - 2.2 8.3 8.3 7.9 6.5 5.8 2.0 1 1 0 1 1 1 0 DivIVA protein Mod_r PF07200.8 EMC99928.1 - 3.4 7.5 11.4 23 4.8 6.1 2.9 2 2 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.3 EMC99928.1 - 4 7.3 6.8 2.2 8.1 0.5 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EMC99928.1 - 5 7.5 11.0 6.5 7.2 2.3 3.2 1 1 1 2 2 2 0 SlyX Patched PF02460.13 EMC99929.1 - 2.8e-75 253.7 7.4 2.2e-74 250.7 5.1 2.2 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EMC99929.1 - 6.9e-52 174.9 5.5 6.9e-52 174.9 3.8 3.5 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EMC99929.1 - 3.8e-05 22.5 12.2 3.8e-05 22.5 8.4 3.5 4 0 0 4 4 4 2 MMPL family DUF2207 PF09972.4 EMC99929.1 - 2.4 6.6 5.7 1.7 7.1 0.5 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Asparaginase_2 PF01112.13 EMC99930.1 - 1.6e-43 148.6 0.1 4.1e-39 134.1 0.0 2.7 2 1 0 2 2 2 2 Asparaginase Proteasome PF00227.21 EMC99932.1 - 9.4e-60 201.1 0.1 1.2e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC99932.1 - 3.6e-14 51.7 0.2 7.5e-14 50.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EMC99932.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EMC99933.1 - 7.3e-09 35.4 6.2 8.6e-07 28.8 0.2 3.8 3 0 0 3 3 3 2 FF domain MHC_I PF00129.13 EMC99933.1 - 0.023 14.0 0.3 0.07 12.4 0.2 1.8 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Phage_holin_4 PF05105.7 EMC99934.1 - 0.029 14.0 0.4 0.029 14.0 0.3 3.1 3 1 1 4 4 4 0 Holin family CHAT PF12770.2 EMC99934.1 - 0.048 12.7 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 CHAT domain D-aminoacyl_C PF07908.7 EMC99935.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region ABC2_membrane PF01061.19 EMC99936.1 - 2.8e-29 101.7 27.2 4.4e-29 101.1 18.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMC99936.1 - 1.3e-25 90.3 0.0 2.1e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC99936.1 - 1.1e-08 35.4 3.0 6.4e-06 26.3 0.4 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC99936.1 - 1.7e-06 27.5 0.1 3.9e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMC99936.1 - 2.8e-05 23.3 0.1 5e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMC99936.1 - 4.1e-05 23.6 0.2 7.8e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC99936.1 - 0.00039 20.5 0.0 0.0029 17.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EMC99936.1 - 0.00095 18.4 0.1 0.0046 16.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMC99936.1 - 0.00099 18.5 0.1 0.0022 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EMC99936.1 - 0.0019 17.9 0.6 0.042 13.6 0.4 2.4 1 1 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMC99936.1 - 0.0051 17.6 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC99936.1 - 0.0086 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMC99936.1 - 0.009 15.9 0.3 0.062 13.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EMC99936.1 - 0.011 15.2 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EMC99936.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EMC99936.1 - 0.036 14.3 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMC99936.1 - 0.037 12.9 0.2 0.061 12.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 EMC99936.1 - 0.046 13.1 0.1 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.1 EMC99936.1 - 0.057 13.3 0.0 0.3 11.0 0.0 2.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EMC99936.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMC99936.1 - 0.083 12.6 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.14 EMC99936.1 - 0.091 12.2 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EMC99936.1 - 0.096 12.8 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.1 EMC99936.1 - 0.097 12.5 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EMC99936.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 EMC99936.1 - 0.19 10.3 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TMPIT PF07851.8 EMC99936.1 - 1.6 7.6 3.9 2.8 6.9 2.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Aminotran_5 PF00266.14 EMC99937.1 - 5.7e-27 94.4 0.0 5e-20 71.5 0.0 3.1 1 1 1 2 2 2 2 Aminotransferase class-V Zn_clus PF00172.13 EMC99938.1 - 1e-07 31.7 8.4 1.5e-07 31.1 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMC99938.1 - 1.6e-05 23.6 1.0 3.5e-05 22.5 0.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EMC99939.1 - 2.3e-57 194.0 8.1 3.8e-57 193.3 5.6 1.3 1 0 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 EMC99939.1 - 5.1 6.4 12.7 22 4.4 0.7 3.1 2 1 0 2 2 2 0 DHHC palmitoyltransferase BUD22 PF09073.5 EMC99940.1 - 4.4e-66 223.7 9.8 5.6e-66 223.4 6.8 1.1 1 0 0 1 1 1 1 BUD22 DUF3867 PF12983.2 EMC99940.1 - 0.2 11.5 0.2 22 4.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) Sec3_C PF09763.4 EMC99941.1 - 1.9e-168 561.7 0.0 3.2e-168 561.0 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EMC99941.1 - 2e-28 98.0 0.1 4.6e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH End3 PF12761.2 EMC99941.1 - 0.00099 18.7 2.1 0.00099 18.7 1.4 2.1 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 Sec3_C_2 PF15278.1 EMC99941.1 - 0.019 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.7 EMC99941.1 - 0.098 11.1 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Vps52 / Sac2 family Ubie_methyltran PF01209.13 EMC99942.1 - 9e-75 250.7 0.0 1.4e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EMC99942.1 - 5.1e-16 58.6 0.0 7.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC99942.1 - 1.2e-12 48.1 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC99942.1 - 1.8e-11 44.3 0.0 3.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC99942.1 - 4.6e-11 42.7 0.0 8.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC99942.1 - 4.7e-10 39.8 0.0 7.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC99942.1 - 3.5e-09 37.2 0.0 5.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC99942.1 - 1.1e-05 25.4 0.0 2.9e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMC99942.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EMC99942.1 - 0.14 11.7 0.0 1.1 8.8 0.0 2.3 3 0 0 3 3 3 0 Hypothetical methyltransferase tRNA-synt_2b PF00587.20 EMC99943.1 - 3.9e-42 143.7 0.3 6.4e-42 143.0 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC99943.1 - 1.4e-15 56.9 0.1 2.8e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EMC99943.1 - 1.1e-14 54.0 0.0 2.1e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EMC99943.1 - 3.2e-11 42.8 0.0 6.6e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain Ytp1 PF10355.4 EMC99944.1 - 9.7e-103 343.0 13.2 9.7e-103 343.0 9.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EMC99944.1 - 5e-27 93.5 3.6 5e-27 93.5 2.5 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) F-box-like PF12937.2 EMC99945.1 - 1.4e-08 34.3 0.0 2.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC99945.1 - 0.0035 16.9 0.1 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 F-box domain TPR_11 PF13414.1 EMC99945.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 EMC99945.1 - 0.024 14.5 0.1 0.38 10.8 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC99945.1 - 0.027 14.0 0.1 1.9 8.2 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.22 EMC99946.1 - 7.2e-63 208.3 0.4 1.9e-20 72.3 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4603 PF15376.1 EMC99946.1 - 0.083 10.0 0.6 0.11 9.6 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Sugar_tr PF00083.19 EMC99948.1 - 4.6e-39 134.2 27.3 5.7e-39 133.9 18.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC99948.1 - 5.7e-15 54.8 30.7 5.7e-15 54.8 21.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SDA1 PF05285.7 EMC99949.1 - 0.047 12.9 6.7 0.056 12.7 4.7 1.1 1 0 0 1 1 1 0 SDA1 AMPKBI PF04739.10 EMC99949.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Daxx PF03344.10 EMC99949.1 - 0.12 10.8 4.9 0.14 10.6 3.4 1.2 1 0 0 1 1 1 0 Daxx Family DUF3246 PF11596.3 EMC99949.1 - 0.14 11.3 2.4 0.18 11.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SMN PF06003.7 EMC99949.1 - 0.3 10.1 5.3 0.13 11.3 0.8 2.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Nucleoplasmin PF03066.10 EMC99949.1 - 0.74 9.3 14.5 0.088 12.3 2.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin BUD22 PF09073.5 EMC99949.1 - 1.6 7.7 5.8 1.7 7.6 4.0 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.8 EMC99949.1 - 3.5 7.1 7.8 5 6.6 5.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.1 EMC99949.1 - 6.2 7.2 14.8 6 7.2 5.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CBS PF00571.23 EMC99950.1 - 4.5e-15 55.1 0.5 2.9e-07 30.1 0.0 5.2 5 0 0 5 5 5 4 CBS domain CRAL_TRIO PF00650.15 EMC99951.1 - 4.3e-35 120.5 0.0 1.1e-34 119.2 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC99951.1 - 1.6e-10 40.9 1.8 2.8e-10 40.1 0.4 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMC99951.1 - 3.9e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain TLD PF07534.11 EMC99953.1 - 5.6e-25 87.9 0.0 1.8e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 TLD Sel1 PF08238.7 EMC99954.1 - 7.9e-15 54.9 26.7 0.00014 22.3 0.0 7.4 6 1 1 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 EMC99954.1 - 0.0023 17.4 1.4 0.038 13.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Glyco_hydro_72 PF03198.9 EMC99955.1 - 2.2e-132 440.8 9.6 2.8e-132 440.4 6.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EMC99955.1 - 1.1e-22 80.3 7.6 3.2e-22 78.8 5.3 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EMC99955.1 - 1.1e-05 24.4 0.2 1.8e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EMC99955.1 - 0.0015 17.8 2.7 0.0039 16.4 1.8 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Troponin-I_N PF11636.3 EMC99956.1 - 0.37 10.5 3.0 0.61 9.8 2.1 1.3 1 0 0 1 1 1 0 Troponin I residues 1-32 Glucan_synthase PF02364.10 EMC99957.1 - 0 1471.4 0.0 0 1470.9 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EMC99957.1 - 1.2e-38 131.5 0.4 3.3e-38 130.2 0.3 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Fig1 PF12351.3 EMC99958.1 - 1.6e-57 194.3 2.2 1.6e-57 194.3 1.5 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EMC99958.1 - 2e-10 40.5 2.2 3.9e-10 39.6 1.5 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EMC99958.1 - 0.0035 16.3 5.6 0.0035 16.3 3.9 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF996 PF06195.8 EMC99958.1 - 0.012 15.6 6.9 0.012 15.6 4.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF996) PGG PF13962.1 EMC99958.1 - 0.025 14.1 2.8 0.069 12.7 2.0 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF202 PF02656.10 EMC99958.1 - 0.093 12.9 0.1 0.093 12.9 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MLTD_N PF06474.7 EMC99958.1 - 0.96 9.6 6.2 0.56 10.4 1.5 2.6 2 0 0 2 2 2 0 MltD lipid attachment motif DUF4131 PF13567.1 EMC99958.1 - 6.3 6.1 15.1 0.12 11.7 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) UCH PF00443.24 EMC99959.1 - 1.4e-61 208.0 0.3 2.3e-61 207.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC99959.1 - 7e-27 94.6 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC99959.1 - 1.1e-06 28.6 0.6 1.1e-06 28.6 0.4 3.3 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.1 EMC99959.1 - 0.00029 20.2 1.6 0.36 10.0 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Piwi PF02171.12 EMC99960.1 - 6.5e-79 265.0 0.0 1.5e-78 263.8 0.0 1.6 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 EMC99960.1 - 7.9e-20 70.5 0.6 1.4e-19 69.7 0.4 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EMC99960.1 - 2.6e-17 61.9 0.1 6.2e-17 60.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Suf PF05843.9 EMC99961.1 - 2.2e-63 214.6 1.2 3.1e-61 207.5 0.0 3.9 6 0 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EMC99961.1 - 1.5e-05 25.1 0.1 0.028 15.0 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Reovirus_L2 PF06016.6 EMC99961.1 - 0.098 9.6 0.0 0.14 9.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) UNC-50 PF05216.8 EMC99962.1 - 5e-77 258.2 9.0 1.4e-76 256.7 6.2 1.6 1 1 0 1 1 1 1 UNC-50 family DUF962 PF06127.6 EMC99962.1 - 0.0039 17.0 1.1 3 7.7 0.0 3.6 1 1 2 3 3 3 2 Protein of unknown function (DUF962) ATG22 PF11700.3 EMC99963.1 - 1.8e-186 620.2 18.7 2.1e-186 620.1 12.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EMC99963.1 - 3.8e-06 25.5 27.3 0.00093 17.6 8.3 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.11 EMC99963.1 - 2.9e-05 22.9 48.8 0.0021 16.8 13.1 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily RRM_1 PF00076.17 EMC99964.1 - 1.1e-07 31.4 0.0 5.3e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC99964.1 - 2.4e-05 24.2 0.1 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC99964.1 - 0.13 12.1 0.1 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_9 PF14658.1 EMC99964.1 - 0.23 11.3 0.3 0.9 9.5 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain RF-1 PF00472.15 EMC99965.1 - 1.7e-16 60.0 0.1 2.3e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 RF-1 domain HLH PF00010.21 EMC99965.1 - 0.11 12.1 0.0 0.34 10.6 0.0 1.8 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain eIF2A PF08662.6 EMC99966.1 - 1.6e-82 275.9 0.1 1e-81 273.2 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EMC99966.1 - 1.1e-06 28.2 0.3 0.64 9.9 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat CDV3 PF15359.1 EMC99966.1 - 0.0033 17.4 0.3 0.0033 17.4 0.2 2.7 3 0 0 3 3 3 1 Carnitine deficiency-associated protein 3 DPPIV_N PF00930.16 EMC99966.1 - 0.061 11.8 0.1 3.5 6.1 0.0 2.8 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 EMC99966.1 - 0.073 12.7 2.1 6.1 6.6 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EMC99966.1 - 0.13 11.6 0.8 17 4.8 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature HEAT_2 PF13646.1 EMC99967.1 - 3.8e-20 71.9 9.9 1.1e-09 38.4 0.2 8.6 4 3 6 11 11 11 7 HEAT repeats HEAT_EZ PF13513.1 EMC99967.1 - 4.7e-18 65.1 20.6 1.8e-09 37.7 0.1 10.4 11 2 2 13 13 12 3 HEAT-like repeat HEAT PF02985.17 EMC99967.1 - 3.6e-13 48.3 18.9 0.0019 18.1 0.0 9.7 12 0 0 12 12 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EMC99967.1 - 1.7e-09 37.9 0.1 0.0048 17.2 0.0 5.6 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EMC99967.1 - 4.2e-06 26.5 0.0 7.9e-05 22.3 0.0 3.3 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EMC99967.1 - 8.3e-06 25.3 2.9 0.0006 19.2 0.2 4.3 4 1 1 5 5 5 1 CLASP N terminal Cnd1 PF12717.2 EMC99967.1 - 0.00012 22.0 2.6 1 9.2 0.2 4.9 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 EMC99967.1 - 0.00082 18.2 6.1 0.0017 17.1 0.4 3.4 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 EMC99967.1 - 0.002 16.5 4.8 0.0028 16.0 0.0 3.2 4 1 0 4 4 4 1 Adaptin N terminal region Arm PF00514.18 EMC99967.1 - 0.023 14.4 8.5 0.048 13.5 0.1 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF4042 PF13251.1 EMC99967.1 - 0.057 12.8 0.8 7.7 5.9 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) TFCD_C PF12612.3 EMC99967.1 - 0.19 11.1 0.0 0.19 11.1 0.0 3.6 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal Defensin_3 PF08131.6 EMC99970.1 - 0.8 9.7 5.3 1.1 9.2 2.1 2.2 2 0 0 2 2 2 0 Defensin-like peptide family Glyco_hydro_16 PF00722.16 EMC99972.1 - 2e-32 112.0 5.8 3.2e-32 111.3 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 EMC99972.1 - 0.047 12.5 0.1 0.068 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF3112 PF11309.3 EMC99972.1 - 0.048 13.4 0.1 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) NAD_binding_10 PF13460.1 EMC99973.1 - 3.3e-17 63.0 0.0 4.5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC99973.1 - 4.8e-15 55.6 0.0 7.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMC99973.1 - 3.7e-13 49.2 0.0 4.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EMC99973.1 - 3.8e-11 42.2 0.0 8e-11 41.1 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMC99973.1 - 2.1e-05 23.5 0.0 0.00035 19.5 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMC99973.1 - 4.4e-05 22.5 0.2 0.0042 16.0 0.1 2.7 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 EMC99973.1 - 0.001 19.0 0.0 0.013 15.4 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC99973.1 - 0.009 15.6 0.0 2.3 7.8 0.0 2.5 3 0 0 3 3 3 1 KR domain Saccharop_dh PF03435.13 EMC99973.1 - 0.013 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EMC99973.1 - 0.037 12.9 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DDE_Tnp_1_3 PF13612.1 EMC99973.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain eIF3_N PF09440.5 EMC99974.1 - 2.9e-43 147.2 2.3 5.5e-43 146.3 1.6 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EMC99974.1 - 3.8e-14 52.8 0.1 1.5e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EMC99974.1 - 0.0017 18.1 0.1 0.0041 16.8 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF771 PF05595.6 EMC99974.1 - 0.021 14.7 0.1 4.3 7.3 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF771) PAPA-1 PF04795.7 EMC99974.1 - 0.077 13.7 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 PAPA-1-like conserved region LXG PF04740.7 EMC99974.1 - 0.077 12.7 3.7 0.11 12.2 0.7 2.4 3 0 0 3 3 3 0 LXG domain of WXG superfamily TPR_19 PF14559.1 EMC99974.1 - 0.093 13.0 0.5 0.7 10.2 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-H2C2 PF09337.5 EMC99975.1 - 3.8e-22 77.4 2.7 6e-22 76.7 1.9 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EMC99975.1 - 0.00046 20.1 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMC99975.1 - 0.00085 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMC99975.1 - 0.0066 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lgl_C PF08596.5 EMC99976.1 - 1.5e-117 392.4 0.0 2.4e-117 391.7 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EMC99976.1 - 2.4e-06 27.1 2.6 0.01 15.7 0.1 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC99976.1 - 0.18 10.4 0.0 0.81 8.3 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like WSC PF01822.14 EMC99977.1 - 7.1e-15 54.7 13.5 7.1e-15 54.7 9.4 2.2 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EMC99977.1 - 1.1e-06 27.7 3.1 3.6e-06 26.1 2.1 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain AJAP1_PANP_C PF15298.1 EMC99977.1 - 0.0065 16.3 11.1 0.012 15.5 7.7 1.4 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Mucin PF01456.12 EMC99977.1 - 0.009 15.7 16.3 0.016 15.0 11.3 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Adeno_E3_CR2 PF02439.10 EMC99977.1 - 0.018 14.5 0.1 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4448 PF14610.1 EMC99977.1 - 0.038 13.4 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 EMC99977.1 - 0.055 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family PepSY_TM_2 PF13703.1 EMC99977.1 - 0.11 12.6 0.2 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix EphA2_TM PF14575.1 EMC99977.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SSP160 PF06933.6 EMC99977.1 - 0.23 9.3 25.7 0.3 9.0 17.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3042 PF11240.3 EMC99977.1 - 1 9.1 3.4 0.65 9.8 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF2076 PF09849.4 EMC99977.1 - 3.4 7.6 5.6 7.3 6.5 3.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1517 PF07466.6 EMC99977.1 - 7.6 5.4 15.3 41 3.0 10.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Pap_E4 PF02711.9 EMC99977.1 - 9.9 7.0 9.9 33 5.3 6.9 1.9 1 0 0 1 1 1 0 E4 protein Ribosomal_L29e PF01779.12 EMC99978.1 - 1.1e-21 76.4 11.3 1.6e-21 75.9 7.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF4482 PF14818.1 EMC99979.1 - 2.1 9.0 9.5 0.18 12.4 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) CP2 PF04516.10 EMC99980.1 - 9.7e-82 273.5 0.0 1.4e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor HlyD_3 PF13437.1 EMC99980.1 - 0.008 16.4 0.2 0.64 10.3 0.0 2.6 3 0 0 3 3 3 1 HlyD family secretion protein zf-HIT PF04438.11 EMC99981.1 - 3.7e-09 36.0 7.0 5.7e-09 35.4 4.8 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF1917 PF08939.5 EMC99981.1 - 0.65 9.6 5.4 0.42 10.3 1.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1917) Abhydrolase_2 PF02230.11 EMC99982.1 - 9e-36 123.3 0.0 1.3e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMC99982.1 - 5.2e-09 36.0 0.0 7.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC99982.1 - 3.4e-06 27.1 0.0 0.019 14.8 0.0 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EMC99982.1 - 0.0046 16.4 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.17 EMC99982.1 - 0.027 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 EMC99982.1 - 0.055 13.0 0.1 0.58 9.6 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold TBPIP PF07106.8 EMC99983.1 - 7.6e-28 97.1 0.6 1e-27 96.7 0.4 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rab5-bind PF09311.6 EMC99983.1 - 0.00012 21.9 1.9 0.00027 20.8 1.3 1.6 1 0 0 1 1 1 1 Rabaptin-like protein Mto2_bdg PF12808.2 EMC99983.1 - 0.01 15.9 3.3 1.2 9.2 0.0 3.1 3 0 0 3 3 3 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Penicillinase_R PF03965.11 EMC99983.1 - 0.012 15.7 0.8 0.027 14.5 0.1 1.9 2 1 0 2 2 2 0 Penicillinase repressor WXG100 PF06013.7 EMC99983.1 - 0.039 13.9 1.2 0.56 10.2 0.9 2.4 1 1 0 1 1 1 0 Proteins of 100 residues with WXG RNA_pol_Rpc34 PF05158.7 EMC99983.1 - 0.13 11.4 0.5 0.25 10.5 0.4 1.4 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DivIC PF04977.10 EMC99983.1 - 0.21 11.1 2.3 1.3 8.5 0.1 2.8 3 0 0 3 3 3 0 Septum formation initiator PEP-utilisers_N PF05524.8 EMC99983.1 - 0.77 9.5 7.1 1.2 8.9 3.7 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal IalB PF06776.7 EMC99984.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein Mito_carr PF00153.22 EMC99985.1 - 9.6e-64 211.1 2.8 5.3e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S2 PF00318.15 EMC99987.1 - 9.1e-45 152.4 0.0 1.5e-44 151.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S2 ADIP PF11559.3 EMC99988.1 - 0.019 14.8 3.8 0.029 14.2 2.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SH3BGR PF04908.10 EMC99988.1 - 0.11 12.4 0.7 0.18 11.7 0.5 1.3 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF2360 PF10152.4 EMC99988.1 - 0.16 12.2 7.9 0.033 14.4 3.2 1.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) HUN PF08729.5 EMC99989.1 - 4.8e-15 55.1 0.1 1.1e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 EMC99990.1 - 6.2e-30 102.8 0.0 1.1e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EMC99990.1 - 1.6e-16 59.6 4.4 1.6e-16 59.6 3.1 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal Rhomboid PF01694.17 EMC99991.1 - 4.9e-18 65.5 9.2 4.9e-18 65.5 6.4 1.6 2 0 0 2 2 2 1 Rhomboid family DUF939 PF06081.6 EMC99991.1 - 0.087 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF939) Gaa1 PF04114.9 EMC99992.1 - 8.9e-91 305.0 0.0 1.1e-90 304.8 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component CALCOCO1 PF07888.6 EMC99994.1 - 0.019 13.2 20.4 0.62 8.2 10.6 2.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Med9 PF07544.8 EMC99994.1 - 2 8.2 11.8 3.4 7.4 4.9 3.4 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FHA PF00498.21 EMC99995.1 - 1.4e-15 57.1 0.0 2.1e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain UME PF08064.8 EMC99997.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 UME (NUC010) domain HSP9_HSP12 PF04119.7 EMC99998.1 - 3.1e-22 78.4 10.8 6e-22 77.4 7.5 1.5 1 0 0 1 1 1 1 Heat shock protein 9/12 AMMECR1 PF01871.12 EMD00001.1 - 9e-41 138.8 0.0 1.8e-40 137.8 0.0 1.4 2 0 0 2 2 2 1 AMMECR1 CDC45 PF02724.9 EMD00001.1 - 3.3 5.6 8.5 4.7 5.1 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2730 PF10805.3 EMD00002.1 - 0.13 11.9 4.9 1.3 8.7 0.5 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Atg14 PF10186.4 EMD00002.1 - 1.3 7.9 4.3 2.6 6.8 3.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CDC45 PF02724.9 EMD00002.1 - 1.7 6.5 6.4 3 5.7 4.4 1.3 1 0 0 1 1 1 0 CDC45-like protein FUSC PF04632.7 EMD00002.1 - 5.8 5.2 7.6 9.6 4.4 5.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Proteasome PF00227.21 EMD00003.1 - 6.4e-45 152.7 0.0 8.9e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EMD00003.1 - 2.4e-12 45.8 1.4 4.8e-12 44.9 1.0 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DNA_ligase_A_M PF01068.16 EMD00004.1 - 5.1e-46 156.5 0.1 2.2e-43 148.0 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMD00004.1 - 2.5e-40 138.1 0.1 5.2e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EMD00004.1 - 1.8e-19 69.9 0.1 5e-18 65.2 0.0 3.1 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Methyltransf_15 PF09445.5 EMD00005.1 - 2.2e-49 167.1 0.0 3e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EMD00005.1 - 1.2e-11 44.4 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EMD00005.1 - 2.2e-10 40.6 0.0 3.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD00005.1 - 8.7e-09 35.9 0.0 1.3e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EMD00005.1 - 2.6e-06 26.9 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EMD00005.1 - 4.1e-06 26.4 0.0 6e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMD00005.1 - 4.2e-05 23.2 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 EMD00005.1 - 0.0046 17.2 0.0 0.0083 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD00005.1 - 0.0056 16.0 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_5 PF01795.14 EMD00005.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Methyltransf_3 PF01596.12 EMD00005.1 - 0.051 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.15 EMD00005.1 - 0.069 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EMD00005.1 - 0.076 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EMD00005.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain BTB PF00651.26 EMD00006.1 - 5.7e-07 29.5 0.0 8.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain IBR PF01485.16 EMD00006.1 - 0.009 15.8 4.8 0.02 14.7 3.3 1.6 1 0 0 1 1 1 1 IBR domain C1_1 PF00130.17 EMD00006.1 - 0.15 11.8 5.7 0.29 10.8 3.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) KH_1 PF00013.24 EMD00007.1 - 1.3e-37 127.2 3.8 2.1e-16 59.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMD00007.1 - 8.2e-28 95.5 10.8 1.2e-11 44.0 1.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMD00007.1 - 1.8e-10 40.2 4.1 0.005 16.3 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMD00007.1 - 0.0034 16.9 1.1 3.8 7.2 0.1 3.2 3 0 0 3 3 3 1 KH domain KH_5 PF13184.1 EMD00007.1 - 0.0066 16.2 6.2 0.99 9.2 0.1 3.5 3 1 0 3 3 3 2 NusA-like KH domain DUF2013 PF09431.5 EMD00010.1 - 2.7e-46 156.7 0.3 9.9e-46 154.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) MFS_1 PF07690.11 EMD00011.1 - 8.5e-17 60.8 36.4 8.5e-17 60.8 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EMD00013.1 - 6.5e-31 107.3 18.8 6.5e-31 107.3 13.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_S10 PF00338.17 EMD00014.1 - 1.6e-28 98.3 0.5 2.1e-28 98.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 EMD00015.1 - 2e-08 33.5 0.1 8.5e-08 31.5 0.0 2.0 2 0 0 2 2 2 1 CUE domain MAM33 PF02330.11 EMD00016.1 - 1.1e-28 100.3 5.0 1.3e-18 67.5 0.0 2.1 1 1 0 2 2 2 2 Mitochondrial glycoprotein DnaJ PF00226.26 EMD00017.1 - 8.6e-07 28.5 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.22 EMD00018.1 - 8e-57 188.9 2.6 5e-22 77.4 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein MFS_1 PF07690.11 EMD00019.1 - 1.3e-28 99.7 25.0 2.4e-28 98.8 17.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 EMD00019.1 - 0.038 13.1 0.2 0.081 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) DUF2530 PF10745.4 EMD00019.1 - 0.076 13.0 0.4 0.076 13.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Mon1 PF03164.9 EMD00023.1 - 2.7e-117 391.8 0.0 3.1e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 CH PF00307.26 EMD00024.1 - 0.01 15.8 0.0 0.4 10.7 0.0 2.6 1 1 0 1 1 1 1 Calponin homology (CH) domain Lactamase_B_3 PF13483.1 EMD00025.1 - 2e-07 30.8 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyridoxal_deC PF00282.14 EMD00026.1 - 1.9e-29 102.3 0.0 6.3e-29 100.5 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMD00026.1 - 0.00026 19.8 0.0 0.001 17.9 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMD00026.1 - 0.00037 19.7 0.1 0.00054 19.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMD00026.1 - 0.0004 19.4 0.0 0.00066 18.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 EMD00026.1 - 0.0021 16.5 0.0 0.004 15.6 0.0 1.3 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF2370 PF10176.4 EMD00027.1 - 8.8e-79 264.1 1.2 1.1e-76 257.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2370) N6-adenineMlase PF10237.4 EMD00028.1 - 7.9e-58 194.6 0.0 1.2e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 EMD00028.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMD00028.1 - 0.079 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 EMD00029.1 - 7.1e-68 228.5 0.0 9.6e-68 228.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD00029.1 - 4.2e-29 101.4 0.0 5.9e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD00029.1 - 4.5e-07 29.1 0.0 7.4e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD00029.1 - 0.00018 21.3 0.2 0.00037 20.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD00029.1 - 0.00039 19.5 0.0 0.0019 17.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMD00029.1 - 0.038 13.3 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Thi4 PF01946.12 EMD00030.1 - 1.3e-102 341.8 0.1 1.5e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMD00030.1 - 2.6e-07 29.8 1.2 5.1e-06 25.6 0.8 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD00030.1 - 0.00011 21.2 0.6 0.00023 20.2 0.4 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMD00030.1 - 0.00038 20.4 1.2 0.0012 18.8 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMD00030.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD00030.1 - 0.0024 17.9 0.4 0.0033 17.4 0.3 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD00030.1 - 0.007 15.2 5.1 0.073 11.8 1.0 2.7 2 1 1 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 EMD00030.1 - 0.0084 15.8 0.4 0.019 14.7 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD00030.1 - 0.014 15.2 0.1 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD00030.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EMD00030.1 - 0.17 10.2 0.7 0.53 8.6 0.7 1.6 2 0 0 2 2 2 0 HI0933-like protein DUF2183 PF09949.4 EMD00033.1 - 7.5e-30 102.8 0.0 1.3e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) RRM_1 PF00076.17 EMD00036.1 - 1.2e-10 40.8 0.0 2.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD00036.1 - 4.6e-10 39.3 0.0 1.7e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD00036.1 - 2.3e-05 24.1 0.0 0.00089 19.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.24 EMD00038.1 - 1.6e-22 79.8 0.6 3.7e-21 75.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.5 EMD00038.1 - 4.1e-21 74.6 0.1 1.3e-20 73.0 0.0 1.9 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 EMD00038.1 - 6.8e-20 70.7 0.1 1.2e-18 66.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD00038.1 - 1.4e-05 24.9 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMD00038.1 - 0.049 13.7 0.4 2.7 8.1 0.1 3.4 2 1 1 3 3 3 0 AAA domain DNA_pol3_delta2 PF13177.1 EMD00038.1 - 2 8.0 5.9 7.6 6.1 1.0 3.3 1 1 2 3 3 3 0 DNA polymerase III, delta subunit Thioredoxin PF00085.15 EMD00039.1 - 4.8e-67 222.1 2.5 3.1e-32 110.3 0.0 4.5 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EMD00039.1 - 8.8e-52 175.5 0.1 5e-38 130.7 0.1 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.12 EMD00039.1 - 1.1e-12 47.4 0.2 2e-12 46.6 0.2 1.4 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 EMD00039.1 - 1.1e-11 44.8 2.5 0.00015 21.8 0.1 4.3 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMD00039.1 - 2.4e-11 43.6 0.4 0.00033 20.7 0.0 4.3 4 2 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EMD00039.1 - 2.2e-10 40.4 0.4 3e-05 23.9 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EMD00039.1 - 1.1e-06 28.3 1.3 0.028 14.1 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EMD00039.1 - 9.9e-05 21.9 2.5 0.51 9.8 0.0 3.7 4 0 0 4 4 4 2 Redoxin Thioredoxin_4 PF13462.1 EMD00039.1 - 0.028 14.4 0.5 20 5.1 0.1 3.7 3 1 1 4 4 4 0 Thioredoxin Pdase_C33_assoc PF14756.1 EMD00039.1 - 0.038 13.7 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C33-associated domain Thioredoxin_3 PF13192.1 EMD00039.1 - 0.097 12.4 0.3 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain DUF2529 PF10740.4 EMD00039.1 - 0.1 12.0 0.1 0.32 10.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) APH PF01636.18 EMD00040.1 - 3.5e-10 40.0 0.1 8.8e-10 38.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family THUMP PF02926.12 EMD00041.1 - 9.2e-11 41.8 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 THUMP domain ASF1_hist_chap PF04729.8 EMD00042.1 - 6.3e-68 227.2 0.0 8.8e-68 226.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0172 PF03665.8 EMD00042.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Nop14 PF04147.7 EMD00042.1 - 9.6 3.9 28.4 12 3.6 19.7 1.0 1 0 0 1 1 1 0 Nop14-like family PCI_Csn8 PF10075.4 EMD00044.1 - 2e-32 111.9 0.0 2.8e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EMD00044.1 - 3.3e-22 79.0 0.1 4.9e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF3626 PF12294.3 EMD00044.1 - 0.11 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Sec34 PF04136.10 EMD00045.1 - 2.5e-29 102.0 0.6 5.1e-29 101.0 0.4 1.5 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.5 EMD00045.1 - 0.03 14.3 1.2 5.6 7.0 0.1 3.0 2 0 0 2 2 2 0 Phasin protein Gpi1 PF05024.10 EMD00046.1 - 6.9e-64 215.0 9.0 1.6e-63 213.8 6.3 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) COG5 PF10392.4 EMD00049.1 - 2.5e-32 111.6 3.0 2.5e-32 111.6 2.1 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Dopey_N PF04118.9 EMD00050.1 - 7.3e-101 336.9 0.0 1.9e-99 332.3 0.0 2.3 2 0 0 2 2 2 2 Dopey, N-terminal Aldose_epim PF01263.15 EMD00051.1 - 5.3e-60 203.0 0.0 6.7e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.13 EMD00052.1 - 5.3e-09 35.8 13.2 1.1e-08 34.8 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 EMD00056.1 - 4.3e-98 328.9 1.8 4.9e-98 328.7 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HopW1-1 PF15457.1 EMD00056.1 - 0.11 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA PKD_channel PF08016.7 EMD00057.1 - 0.06 11.7 9.1 0.62 8.4 0.9 2.3 2 0 0 2 2 2 0 Polycystin cation channel YbjM PF11045.3 EMD00057.1 - 5.2 6.8 13.0 0.91 9.2 1.1 3.0 1 1 1 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae EMG1 PF03587.9 EMD00058.1 - 1.2e-77 259.8 0.0 1.3e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase_2 PF12681.2 EMD00059.1 - 0.0014 19.2 0.0 0.004 17.7 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Hydrolase_2 PF07486.7 EMD00060.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Cell Wall Hydrolase PhyH PF05721.8 EMD00061.1 - 3.8e-16 59.7 0.1 4.5e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 EMD00061.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 EMD00061.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Lyase_aromatic PF00221.14 EMD00062.1 - 1.1e-155 518.7 8.4 1.4e-155 518.3 5.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase zf-RING_2 PF13639.1 EMD00063.1 - 5e-09 35.8 5.5 5e-09 35.8 3.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMD00063.1 - 2.5e-07 30.2 3.0 3.6e-07 29.7 2.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD00063.1 - 1.4e-06 27.8 3.4 2.1e-06 27.2 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD00063.1 - 1.7e-06 27.9 4.5 2.7e-06 27.2 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD00063.1 - 0.00019 21.4 2.3 0.00019 21.4 1.6 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMD00063.1 - 0.012 15.2 2.4 0.02 14.6 1.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EMD00063.1 - 0.066 13.0 2.1 0.82 9.5 0.9 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HIT PF01230.18 EMD00064.1 - 2.7e-23 82.3 0.4 3.7e-23 81.9 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMD00064.1 - 4.1e-15 56.0 0.1 5.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EMD00064.1 - 9.9e-05 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF1275 PF06912.6 EMD00065.1 - 2e-32 112.0 18.4 2.5e-32 111.7 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Cupin_1 PF00190.17 EMD00066.1 - 3.8e-33 113.9 0.0 1.1e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EMD00066.1 - 2.1e-24 84.8 1.1 1e-11 44.1 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EMD00066.1 - 7.9e-12 44.4 0.0 0.00011 21.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMD00066.1 - 3.1e-07 30.1 0.9 0.00066 19.3 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EMD00066.1 - 0.00012 21.7 0.1 0.3 10.6 0.0 2.4 2 0 0 2 2 2 2 Cupin CENP-C_C PF11699.3 EMD00066.1 - 0.0029 17.5 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 Mif2/CENP-C like MannoseP_isomer PF01050.13 EMD00066.1 - 0.0042 16.7 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase FdtA PF05523.6 EMD00066.1 - 0.007 15.8 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 2 WxcM-like, C-terminal ARD PF03079.9 EMD00066.1 - 0.076 12.9 0.1 7 6.5 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family Abhydrolase_6 PF12697.2 EMD00067.1 - 1.3e-33 116.7 0.0 1.5e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD00067.1 - 1.6e-19 70.3 0.0 8.4e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD00067.1 - 3.8e-19 68.8 0.0 8.7e-19 67.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMD00067.1 - 1.8e-10 39.7 0.0 2.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.16 EMD00067.1 - 1.2e-06 27.9 0.0 0.0021 17.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EMD00067.1 - 0.00016 21.4 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.15 EMD00067.1 - 0.0006 19.3 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 EMD00067.1 - 0.0011 18.3 0.0 0.8 8.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EMD00067.1 - 0.0018 17.7 0.0 2.2 7.6 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EMD00067.1 - 0.0032 17.1 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.4 EMD00067.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Lipase_3 PF01764.20 EMD00067.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EMD00067.1 - 0.02 14.4 0.1 0.028 13.9 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EMD00067.1 - 0.021 15.0 0.0 0.022 14.9 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EMD00067.1 - 0.063 12.1 0.2 0.1 11.4 0.1 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF2048 PF09752.4 EMD00067.1 - 0.083 11.7 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) PGAP1 PF07819.8 EMD00067.1 - 0.13 11.8 0.6 0.35 10.4 0.4 1.8 1 1 0 1 1 1 0 PGAP1-like protein Seryl_tRNA_N PF02403.17 EMD00068.1 - 0.0057 16.6 1.1 1.9 8.5 0.3 2.6 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Takusan PF04822.8 EMD00068.1 - 0.43 10.3 5.3 14 5.5 0.1 3.2 3 0 0 3 3 3 0 Takusan DivIVA PF05103.8 EMD00068.1 - 2.1 8.3 5.0 1.4 8.9 1.8 1.9 2 0 0 2 2 2 0 DivIVA protein TPR_11 PF13414.1 EMD00069.1 - 8.4e-14 50.9 9.7 0.00012 21.6 0.0 6.8 7 1 0 7 7 7 3 TPR repeat TPR_16 PF13432.1 EMD00069.1 - 4.5e-12 46.2 17.1 4.2e-08 33.6 0.2 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD00069.1 - 4.9e-08 33.2 7.0 3.7e-06 27.1 0.0 5.4 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD00069.1 - 1.7e-07 30.6 15.2 0.089 12.7 0.0 7.7 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD00069.1 - 4.3e-07 29.2 0.8 0.76 9.6 0.2 5.8 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMD00069.1 - 1.7e-05 24.2 7.0 16 5.2 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD00069.1 - 3e-05 24.2 18.5 0.00039 20.8 0.2 7.6 7 1 1 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD00069.1 - 0.00023 20.9 0.5 0.14 12.0 0.0 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EMD00069.1 - 0.00046 20.0 20.8 2.2 8.2 0.1 8.5 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMD00069.1 - 0.00067 19.4 6.7 3.2 7.8 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD00069.1 - 0.0011 19.2 3.2 0.63 10.6 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMD00069.1 - 0.0033 17.4 2.7 0.15 12.2 0.0 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD00069.1 - 0.018 14.8 11.3 1.4 8.8 0.1 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EMD00069.1 - 0.021 15.0 0.0 6.4 7.0 0.0 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_4 PF07721.9 EMD00069.1 - 0.046 14.1 0.1 0.046 14.1 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EMD00069.1 - 0.4 10.8 0.0 0.4 10.8 0.0 4.2 6 0 0 6 6 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EMD00069.1 - 0.58 10.3 0.0 0.58 10.3 0.0 5.4 6 1 1 7 7 6 0 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EMD00070.1 - 1.2e-56 191.7 0.0 2.1e-56 190.9 0.0 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein COX6B PF02297.12 EMD00071.1 - 3.1e-23 81.5 3.8 3.8e-23 81.2 2.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EMD00071.1 - 0.039 13.7 2.1 0.039 13.7 1.5 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EMD00071.1 - 0.13 12.3 2.2 0.2 11.6 1.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 ARID PF01388.16 EMD00072.1 - 2.2e-15 56.2 0.1 6.8e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Mis14 PF08641.7 EMD00074.1 - 0.49 10.4 4.7 0.34 10.9 1.9 1.7 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Img2 PF05046.9 EMD00075.1 - 5.8e-19 68.1 0.0 8e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Peptidase_C2 PF00648.16 EMD00076.1 - 2.5e-22 79.2 0.0 6.4e-22 77.9 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMD00076.1 - 9e-15 54.5 0.0 3.5e-14 52.6 0.0 2.0 1 1 0 1 1 1 1 Calpain large subunit, domain III MIT PF04212.13 EMD00076.1 - 0.0008 19.2 1.2 0.0014 18.4 0.9 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EMD00077.1 - 4.2e-55 183.4 0.2 6.9e-20 70.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UDG PF03167.14 EMD00078.1 - 1.1e-23 83.4 0.1 1.7e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Aldo_ket_red PF00248.16 EMD00079.1 - 3.5e-74 249.1 0.0 4.3e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyridox_oxidase PF01243.15 EMD00080.1 - 1.4e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EMD00080.1 - 0.1 12.4 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase ADH_N PF08240.7 EMD00081.1 - 6.5e-11 41.9 0.0 1.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMD00081.1 - 4.8e-10 40.4 0.0 8.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMD00081.1 - 1.1e-09 37.8 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_6 PF13344.1 EMD00081.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Glyco_hydro_11 PF00457.12 EMD00082.1 - 4.3e-55 185.8 19.0 5e-55 185.6 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Pyocin_S PF06958.7 EMD00083.1 - 0.018 15.4 0.4 0.033 14.5 0.2 1.4 1 0 0 1 1 1 0 S-type Pyocin Sugar_tr PF00083.19 EMD00084.1 - 4.2e-83 279.4 17.2 4.9e-83 279.2 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD00084.1 - 6.8e-37 126.9 11.0 6.8e-37 126.9 7.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD00084.1 - 6.4e-06 24.6 0.6 6.4e-06 24.6 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EMD00084.1 - 0.014 13.5 6.6 0.06 11.4 0.2 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 EMD00084.1 - 0.077 11.0 10.7 0.85 7.5 0.1 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Y_phosphatase PF00102.22 EMD00086.1 - 2.7e-50 170.8 0.0 5.5e-50 169.8 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMD00086.1 - 0.0024 17.4 0.2 0.0076 15.8 0.1 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMD00086.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Chromo PF00385.19 EMD00087.1 - 1.8e-06 27.5 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2828 PF11443.3 EMD00088.1 - 4.9e-170 566.2 0.0 5.6e-170 566.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Med14 PF08638.6 EMD00089.1 - 2.3e-55 186.9 0.0 3.6e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 Prefoldin PF02996.12 EMD00090.1 - 2.8e-31 107.6 0.2 5.8e-31 106.6 0.1 1.5 1 1 1 2 2 2 1 Prefoldin subunit HR1 PF02185.11 EMD00090.1 - 0.0076 15.9 0.2 0.031 14.0 0.0 1.9 2 0 0 2 2 2 1 Hr1 repeat Prefoldin_2 PF01920.15 EMD00090.1 - 0.01 15.5 1.5 0.053 13.2 0.1 2.2 2 1 1 3 3 3 0 Prefoldin subunit Filament PF00038.16 EMD00090.1 - 0.031 13.7 2.2 3.5 7.0 1.5 2.0 1 1 0 1 1 1 0 Intermediate filament protein Cpn60_TCP1 PF00118.19 EMD00091.1 - 3.7e-147 490.8 0.0 4.2e-147 490.6 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.13 EMD00092.1 - 8.1e-58 193.9 0.1 1.9e-57 192.7 0.1 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMD00092.1 - 3.6e-24 84.3 0.1 9e-24 83.0 0.1 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EMD00092.1 - 6.5e-20 71.0 0.0 6.5e-20 71.0 0.0 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Hex_IIIa PF02455.11 EMD00093.1 - 0.035 12.7 3.1 0.044 12.4 2.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) CDC45 PF02724.9 EMD00093.1 - 0.2 9.6 6.8 0.22 9.4 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein zf-RING_2 PF13639.1 EMD00094.1 - 1.4e-08 34.4 6.7 3.3e-08 33.2 4.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD00094.1 - 0.00014 21.8 2.7 0.00014 21.8 1.9 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger FANCL_C PF11793.3 EMD00094.1 - 0.00078 19.3 5.0 0.00078 19.3 3.5 1.8 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.1 EMD00094.1 - 0.004 16.8 7.9 0.004 16.8 5.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMD00094.1 - 0.0043 16.8 2.8 0.0043 16.8 2.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EMD00094.1 - 0.03 14.0 5.3 0.071 12.7 3.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMD00094.1 - 0.038 13.6 7.1 0.084 12.5 4.9 1.6 1 0 0 1 1 1 0 PHD-finger Nucleo_P87 PF07267.6 EMD00094.1 - 0.15 10.7 1.5 0.19 10.3 1.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RINGv PF12906.2 EMD00094.1 - 0.86 9.6 6.8 1.8 8.6 4.7 1.6 1 0 0 1 1 1 0 RING-variant domain Exo_endo_phos PF03372.18 EMD00095.1 - 3e-22 79.7 1.0 3e-22 79.7 0.7 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EMD00095.1 - 3.4e-16 58.4 13.0 2.6e-08 33.3 0.4 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD00095.1 - 1.6e-11 43.7 5.4 5e-08 32.5 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMD00095.1 - 2.4e-07 29.8 3.6 0.048 13.6 0.0 4.8 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EMD00095.1 - 1.7e-05 24.2 10.2 0.11 12.7 0.1 4.8 4 0 0 4 4 4 2 Leucine rich repeat Phage_fiber PF03335.8 EMD00095.1 - 0.0059 16.0 1.6 0.019 14.5 1.1 2.0 1 0 0 1 1 1 1 Phage tail fibre repeat LRR_6 PF13516.1 EMD00095.1 - 0.014 15.4 4.2 1.1 9.5 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat TIP_N PF12457.3 EMD00096.1 - 0.094 12.7 2.7 0.14 12.2 1.9 1.3 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Preseq_ALAS PF09029.5 EMD00096.1 - 0.63 10.0 3.3 2.2 8.2 0.3 2.2 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence LSM PF01423.17 EMD00097.1 - 3.4e-14 52.1 0.0 4.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMD00097.1 - 0.00092 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 EMD00097.1 - 0.041 14.1 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Pkr1 PF08636.5 EMD00098.1 - 2.7e-33 113.8 5.8 3.5e-33 113.4 4.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 SnoaL PF07366.7 EMD00099.1 - 0.00016 21.2 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMD00099.1 - 0.0024 18.2 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain TraY PF05509.6 EMD00100.1 - 0.21 11.3 4.1 7.4 6.4 1.7 2.5 2 0 0 2 2 2 0 TraY domain 4HBT_2 PF13279.1 EMD00101.1 - 5e-27 94.7 0.0 7.7e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EMD00101.1 - 0.0086 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Complex1_LYR_2 PF13233.1 EMD00102.1 - 5.4e-06 26.8 0.0 6.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMD00102.1 - 0.0073 16.0 0.1 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD00102.1 - 0.04 14.1 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Complex1_LYR-like Methyltransf_25 PF13649.1 EMD00103.1 - 1.9e-11 44.1 0.0 3.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD00103.1 - 8e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD00103.1 - 4.1e-07 29.7 0.0 6.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD00103.1 - 4.8e-06 26.3 0.0 8.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD00103.1 - 0.00014 22.3 0.0 0.00044 20.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD00103.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD00103.1 - 0.00051 20.4 0.0 0.00095 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMD00103.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EMD00103.1 - 0.043 13.4 0.0 0.13 11.8 0.0 1.8 2 1 0 2 2 2 0 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EMD00103.1 - 0.056 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family OB_NTP_bind PF07717.11 EMD00104.1 - 2.1e-18 66.2 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMD00104.1 - 9.2e-18 64.1 0.2 1.8e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMD00104.1 - 6.4e-14 51.5 0.0 1.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FUSC PF04632.7 EMD00104.1 - 0.18 10.2 5.3 0.28 9.5 3.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family WLM PF08325.5 EMD00105.1 - 5.9e-46 156.6 0.3 1.5e-45 155.3 0.2 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EMD00105.1 - 4.8e-07 29.7 0.6 1.1e-06 28.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.13 EMD00105.1 - 0.0086 15.1 1.3 0.0086 15.1 0.9 2.5 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Abhydrolase_1 PF00561.15 EMD00106.1 - 9.6e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD00106.1 - 2.5e-08 34.0 0.1 3.6e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD00106.1 - 3.6e-06 26.7 0.0 1.6e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD00106.1 - 0.0066 15.7 0.0 0.018 14.2 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EMD00106.1 - 0.0077 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S10 PF00450.17 EMD00106.1 - 0.037 13.2 0.1 9.1 5.3 0.1 2.3 2 0 0 2 2 2 0 Serine carboxypeptidase Kelch_3 PF13415.1 EMD00107.1 - 1.9e-30 104.2 9.3 1.6e-10 40.8 0.0 7.3 8 0 0 8 8 8 3 Galactose oxidase, central domain DUF4110 PF13422.1 EMD00107.1 - 9.2e-26 89.5 2.3 9.2e-26 89.5 1.6 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EMD00107.1 - 1.2e-23 82.5 16.5 3.9e-10 39.3 0.1 5.7 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMD00107.1 - 4e-20 71.3 8.7 0.00091 19.1 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EMD00107.1 - 2.4e-19 68.5 5.5 1.2e-05 25.2 0.2 5.6 4 1 1 5 5 5 5 Kelch motif Kelch_2 PF07646.10 EMD00107.1 - 5.3e-12 44.9 5.3 0.026 14.3 0.0 6.0 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 EMD00107.1 - 1.2e-08 34.3 3.6 0.2 11.2 0.0 5.6 5 1 0 5 5 5 3 Kelch motif Nop14 PF04147.7 EMD00107.1 - 0.00078 17.5 6.5 0.00078 17.5 4.5 2.1 2 0 0 2 2 2 1 Nop14-like family Rotamase PF00639.16 EMD00107.1 - 1.6 9.5 7.4 0.31 11.8 0.1 3.3 3 2 1 4 4 4 0 PPIC-type PPIASE domain Prefoldin_2 PF01920.15 EMD00108.1 - 1.2e-23 82.8 12.5 1.6e-23 82.4 8.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EMD00108.1 - 1.5e-05 24.6 4.2 1.6e-05 24.5 2.6 1.3 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EMD00108.1 - 0.0013 18.3 9.4 0.0099 15.5 0.3 2.4 2 0 0 2 2 2 1 Prefoldin subunit Rootletin PF15035.1 EMD00108.1 - 0.002 18.1 3.8 0.002 18.1 2.6 1.5 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.6 EMD00108.1 - 0.0071 15.0 10.7 0.0091 14.6 7.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 EMD00108.1 - 0.013 15.0 15.6 0.032 13.8 10.8 1.6 1 1 0 1 1 1 0 IncA protein Spc24 PF08286.6 EMD00108.1 - 0.047 13.3 9.7 0.047 13.3 2.2 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DegS PF05384.6 EMD00108.1 - 0.047 12.9 7.8 0.25 10.5 1.4 2.2 2 0 0 2 2 2 0 Sensor protein DegS CENP-F_leu_zip PF10473.4 EMD00108.1 - 0.073 12.9 11.9 0.19 11.5 2.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERp29 PF07749.7 EMD00108.1 - 0.079 13.6 4.0 0.14 12.8 2.8 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DASH_Dad3 PF08656.5 EMD00108.1 - 0.22 11.2 4.2 0.57 9.9 1.4 2.1 1 1 1 2 2 2 0 DASH complex subunit Dad3 Mto2_bdg PF12808.2 EMD00108.1 - 0.24 11.5 1.8 0.83 9.8 0.7 2.2 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Macoilin PF09726.4 EMD00108.1 - 0.25 9.5 9.6 0.35 9.0 6.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Cep57_CLD_2 PF14197.1 EMD00108.1 - 0.3 11.0 5.6 0.22 11.4 1.8 2.2 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 GAS PF13851.1 EMD00108.1 - 0.31 10.1 11.7 0.86 8.7 3.7 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 EMD00108.1 - 0.32 11.2 6.2 3 8.1 0.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein STAT_alpha PF01017.15 EMD00108.1 - 0.34 10.6 9.9 1.8 8.2 2.3 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain Uds1 PF15456.1 EMD00108.1 - 0.35 10.8 5.7 0.57 10.1 4.0 1.5 1 1 0 1 1 1 0 Up-regulated During Septation DUF972 PF06156.8 EMD00108.1 - 0.55 10.6 8.5 1.3 9.4 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 EMD00108.1 - 0.77 9.9 7.6 2.2 8.4 1.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.6 EMD00108.1 - 0.84 9.5 7.0 7.2 6.4 1.0 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.6 EMD00108.1 - 0.97 9.2 10.6 0.42 10.4 1.6 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 EMD00108.1 - 1.1 9.0 10.1 0.63 9.7 2.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 EMD00108.1 - 1.1 9.0 9.1 2 8.2 1.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2312 PF10073.4 EMD00108.1 - 1.1 8.6 5.0 1.3 8.4 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Muted PF14942.1 EMD00108.1 - 1.2 9.0 6.7 0.89 9.4 0.1 2.1 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Occludin_ELL PF07303.8 EMD00108.1 - 1.2 9.8 7.3 2.6 8.8 1.6 2.1 1 1 1 2 2 2 0 Occludin homology domain Tropomyosin_1 PF12718.2 EMD00108.1 - 1.4 8.7 12.5 3.1 7.6 0.5 2.1 2 0 0 2 2 2 0 Tropomyosin like Spectrin PF00435.16 EMD00108.1 - 1.5 9.1 11.4 6.1 7.1 0.5 2.1 2 0 0 2 2 2 0 Spectrin repeat DUF4140 PF13600.1 EMD00108.1 - 1.8 9.0 9.4 16 6.0 2.5 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sas10_Utp3 PF04000.10 EMD00108.1 - 1.9 8.7 5.2 9.6 6.4 1.8 2.3 2 1 0 2 2 2 0 Sas10/Utp3/C1D family CCDC155 PF14662.1 EMD00108.1 - 2.2 7.8 13.7 64 3.0 9.4 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 TMPIT PF07851.8 EMD00108.1 - 2.4 7.1 6.5 3.2 6.7 4.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein Laminin_I PF06008.9 EMD00108.1 - 2.5 7.3 11.7 8.2 5.6 8.1 1.7 1 1 0 1 1 1 0 Laminin Domain I HAUS-augmin3 PF14932.1 EMD00108.1 - 2.6 7.1 11.6 1.1 8.3 1.5 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 APG6 PF04111.7 EMD00108.1 - 2.6 6.9 12.8 12 4.8 8.8 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 YgaB PF14182.1 EMD00108.1 - 3.7 7.8 14.3 0.74 10.0 2.3 2.3 2 0 0 2 2 2 0 YgaB-like protein EAP30 PF04157.11 EMD00108.1 - 3.7 6.6 9.1 1.4 8.0 2.6 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family Snf7 PF03357.16 EMD00108.1 - 5.3 6.3 12.2 0.93 8.8 2.3 2.2 2 0 0 2 2 2 0 Snf7 TPR_MLP1_2 PF07926.7 EMD00108.1 - 5.5 6.7 15.5 12 5.7 8.2 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Kinetocho_Slk19 PF12709.2 EMD00108.1 - 6.3 6.9 11.3 24 5.0 0.8 3.2 2 2 1 3 3 3 0 Central kinetochore-associated Fzo_mitofusin PF04799.8 EMD00108.1 - 7.2 5.9 8.3 6.3 6.1 1.2 2.1 2 0 0 2 2 2 0 fzo-like conserved region Atg14 PF10186.4 EMD00108.1 - 7.3 5.4 10.8 11 4.8 7.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EMD00108.1 - 7.9 6.0 12.9 5.2 6.6 3.6 2.0 1 1 1 2 2 2 0 Mnd1 family Seryl_tRNA_N PF02403.17 EMD00108.1 - 9.8 6.2 9.8 48 4.0 6.7 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AAA PF00004.24 EMD00109.1 - 1.2e-42 145.2 0.0 2.2e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMD00109.1 - 3e-29 100.6 0.0 9.6e-29 99.0 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EMD00109.1 - 3.7e-21 74.7 6.0 1.1e-20 73.2 3.8 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EMD00109.1 - 2.5e-06 28.3 0.2 1.1e-05 26.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EMD00109.1 - 5e-06 25.7 0.0 8.4e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMD00109.1 - 1.2e-05 25.5 0.1 0.0011 19.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMD00109.1 - 1.3e-05 24.9 0.0 8.5e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMD00109.1 - 1.4e-05 25.0 0.0 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EMD00109.1 - 2e-05 24.4 0.0 5.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMD00109.1 - 2.1e-05 23.9 0.0 5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EMD00109.1 - 6.3e-05 23.0 0.0 0.0084 16.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 EMD00109.1 - 8.1e-05 21.5 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EMD00109.1 - 0.00014 21.9 0.0 0.0012 18.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EMD00109.1 - 0.00019 20.8 0.1 0.19 11.1 0.1 2.8 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 EMD00109.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMD00109.1 - 0.00062 18.7 0.0 0.0018 17.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 EMD00109.1 - 0.0056 16.9 0.2 0.016 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EMD00109.1 - 0.006 15.6 0.7 0.16 11.0 0.0 2.8 3 1 1 4 4 2 1 Zeta toxin AAA_24 PF13479.1 EMD00109.1 - 0.0066 16.0 0.4 0.026 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMD00109.1 - 0.019 14.1 0.0 0.062 12.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMD00109.1 - 0.022 14.4 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EMD00109.1 - 0.027 14.1 0.0 0.63 9.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 EMD00109.1 - 0.03 14.1 0.0 0.072 12.9 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Torsin PF06309.6 EMD00109.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Torsin Arch_ATPase PF01637.13 EMD00109.1 - 0.036 13.7 1.1 0.21 11.2 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase PhoH PF02562.11 EMD00109.1 - 0.042 13.0 0.4 0.095 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 EMD00109.1 - 0.047 12.5 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 USP8_dimer PF08969.6 EMD00109.1 - 0.058 13.3 5.3 0.12 12.3 3.6 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain KAP_NTPase PF07693.9 EMD00109.1 - 0.081 11.8 1.5 14 4.5 0.0 2.8 2 1 0 2 2 2 0 KAP family P-loop domain AAA_21 PF13304.1 EMD00109.1 - 0.093 12.6 0.4 2.8 7.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 EMD00109.1 - 0.1 11.7 0.0 7.1 5.6 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.1 EMD00109.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EMD00109.1 - 0.13 11.8 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Peptidase_M28 PF04389.12 EMD00109.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M28 SMC_N PF02463.14 EMD00110.1 - 4e-78 261.6 0.0 6.4e-78 260.9 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMD00110.1 - 2.8e-28 98.3 0.0 8.1e-28 96.8 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMD00110.1 - 1.5e-12 48.1 0.8 4.1e-05 23.6 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EMD00110.1 - 7.7e-06 25.2 2.2 0.0023 17.0 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain Reo_sigmaC PF04582.7 EMD00110.1 - 2.3e-05 23.7 23.9 0.00075 18.7 1.5 5.8 3 2 3 6 6 6 2 Reovirus sigma C capsid protein AAA_29 PF13555.1 EMD00110.1 - 0.0002 20.8 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2968 PF11180.3 EMD00110.1 - 0.00032 20.1 4.1 0.00032 20.1 2.8 6.6 3 2 3 7 7 7 2 Protein of unknown function (DUF2968) FlxA PF14282.1 EMD00110.1 - 0.00047 20.0 1.7 0.00047 20.0 1.2 6.2 2 2 3 6 6 6 1 FlxA-like protein TPR_MLP1_2 PF07926.7 EMD00110.1 - 0.00079 19.1 73.5 0.00094 18.9 0.0 8.9 3 2 5 9 9 9 4 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.6 EMD00110.1 - 0.012 15.0 1.0 0.012 15.0 0.7 5.2 3 2 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) ABC_tran PF00005.22 EMD00110.1 - 0.046 14.0 9.2 1.7 8.9 0.0 4.9 4 1 0 4 4 4 0 ABC transporter GAS PF13851.1 EMD00110.1 - 0.11 11.7 79.6 0.013 14.7 14.7 6.1 3 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 EMD00110.1 - 1.1 9.0 57.5 0.076 12.7 0.5 7.1 5 2 2 7 7 7 0 Laminin Domain II AAA_13 PF13166.1 EMD00110.1 - 1.8 6.9 75.7 0.037 12.4 8.1 5.7 3 2 1 5 5 5 0 AAA domain RINT1_TIP1 PF04437.8 EMD00111.1 - 3.1e-136 454.8 0.0 5.3e-136 454.0 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family RdRP PF05183.7 EMD00113.1 - 8.8e-153 510.0 0.0 1.2e-152 509.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase MARVEL PF01284.18 EMD00114.1 - 0.0009 19.0 10.6 0.002 17.9 7.3 1.7 1 1 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 EMD00114.1 - 0.019 14.6 14.3 0.013 15.1 5.4 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling DIM PF08194.7 EMD00114.1 - 0.31 11.0 0.2 0.31 11.0 0.1 3.1 3 0 0 3 3 3 0 DIM protein p450 PF00067.17 EMD00115.1 - 2e-54 184.8 0.0 2.7e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-rbx1 PF12678.2 EMD00116.1 - 6.3e-10 39.0 0.5 2.1e-09 37.3 0.4 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMD00116.1 - 1.1e-09 37.9 1.9 1.1e-09 37.9 1.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMD00116.1 - 2.7e-06 26.9 3.4 9.3e-06 25.2 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD00116.1 - 1.2e-05 24.9 1.7 3.7e-05 23.3 1.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD00116.1 - 4.3e-05 23.4 1.1 4.3e-05 23.4 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD00116.1 - 4.9e-05 22.8 0.6 0.00012 21.6 0.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD00116.1 - 0.005 16.6 0.5 0.013 15.3 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMD00116.1 - 0.026 14.1 0.6 0.06 12.9 0.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EMD00116.1 - 0.16 11.5 0.1 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EMD00116.1 - 0.17 11.6 2.3 0.44 10.3 1.6 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMD00116.1 - 0.25 11.2 1.0 0.53 10.1 0.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF533 PF04391.7 EMD00117.1 - 0.37 10.1 14.3 0.49 9.7 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF533) DUF2726 PF10881.3 EMD00117.1 - 2.8 7.5 5.1 9.2 5.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2726) ADH_zinc_N PF00107.21 EMD00118.1 - 2.1e-15 56.4 0.1 4.5e-15 55.3 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD00118.1 - 3.1e-08 33.3 0.1 9.5e-08 31.7 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 EMD00118.1 - 0.022 14.5 1.4 0.045 13.5 0.4 1.9 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N_2 PF13602.1 EMD00118.1 - 0.085 13.7 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ras PF00071.17 EMD00119.1 - 2.5e-40 137.5 0.0 3.2e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD00119.1 - 2.9e-14 53.5 0.0 4.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD00119.1 - 2.9e-05 23.3 0.0 3.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD00119.1 - 0.00014 21.3 0.0 0.0023 17.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMD00119.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.13 EMD00119.1 - 0.018 14.5 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Flocculin_t3 PF13928.1 EMD00119.1 - 0.072 13.2 2.2 0.17 12.0 1.5 1.7 1 1 0 1 1 1 0 Flocculin type 3 repeat PAS_9 PF13426.1 EMD00120.1 - 3.2e-31 107.7 0.0 4.7e-17 62.2 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EMD00120.1 - 6.8e-16 58.1 0.0 6.9e-10 38.8 0.0 3.9 4 0 0 4 4 4 3 PAS fold GATA PF00320.22 EMD00120.1 - 1.4e-14 53.1 6.8 3.6e-14 51.8 4.7 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EMD00120.1 - 4.2e-14 52.2 0.0 7.1e-06 25.7 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.1 EMD00120.1 - 5e-10 39.3 0.0 0.00014 21.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMD00120.1 - 3.1e-06 27.1 0.0 0.26 11.3 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 EMD00120.1 - 0.022 14.5 0.0 0.58 10.1 0.0 2.4 2 0 0 2 2 2 0 PAS domain Cellulase PF00150.13 EMD00121.1 - 1.6e-08 34.1 2.8 2.8e-08 33.3 1.9 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ABM PF03992.11 EMD00122.1 - 0.0018 18.2 1.1 0.17 11.9 0.0 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Aldolase_II PF00596.16 EMD00123.1 - 2e-25 89.4 0.3 3.9e-25 88.5 0.2 1.4 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.13 EMD00124.1 - 2.3e-13 49.6 0.0 3.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD00124.1 - 1.8e-07 30.9 8.5 3e-07 30.2 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M3 PF01432.15 EMD00125.1 - 2.1e-124 416.0 0.0 3.4e-124 415.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EMD00125.1 - 0.0054 16.1 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M50B-like ApoO PF09769.4 EMD00126.1 - 1.6e-45 154.6 0.2 5.6e-45 152.8 0.0 1.9 2 0 0 2 2 2 1 Apolipoprotein O IBR PF01485.16 EMD00127.1 - 2.4e-11 43.3 51.5 3e-06 27.0 3.5 4.3 4 0 0 4 4 4 3 IBR domain TRAUB PF08164.7 EMD00128.1 - 6.1e-28 96.7 0.4 6.1e-28 96.7 0.3 2.2 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EMD00128.1 - 3.1e-26 92.0 2.8 3.1e-26 92.0 1.9 2.4 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Cyanate_lyase PF02560.9 EMD00128.1 - 0.0069 15.8 0.2 0.022 14.2 0.0 1.9 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain BSD PF03909.12 EMD00129.1 - 1.3e-12 47.2 1.7 2.5e-12 46.3 1.2 1.5 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.9 EMD00129.1 - 0.089 12.4 0.2 0.35 10.5 0.1 1.9 1 0 0 1 1 1 0 Sigma-70 region 2 DUF883 PF05957.8 EMD00129.1 - 3 8.3 10.7 3 8.3 0.8 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) PEX11 PF05648.9 EMD00130.1 - 6.3e-70 234.9 1.0 7e-70 234.7 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ARF7EP_C PF14949.1 EMD00130.1 - 0.16 12.4 0.1 0.27 11.6 0.1 1.3 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Pkinase PF00069.20 EMD00131.1 - 3.8e-11 42.6 0.0 7.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF1501 PF07394.7 EMD00131.1 - 1.3 7.7 5.7 2.3 6.9 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) RNase_H PF00075.19 EMD00132.1 - 2.4e-08 34.4 0.0 3.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNase H RNase_H PF00075.19 EMD00133.1 - 0.00032 21.0 0.0 0.055 13.8 0.0 2.3 2 0 0 2 2 2 2 RNase H Melibiase PF02065.13 EMD00134.1 - 7.7e-148 492.3 0.0 1e-147 491.9 0.0 1.2 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 EMD00134.1 - 0.00018 20.4 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 IFT57 PF10498.4 EMD00135.1 - 0.049 12.3 0.2 0.06 12.0 0.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Isochorismatase PF00857.15 EMD00136.1 - 2.2e-31 109.1 0.0 2.6e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family GFA PF04828.9 EMD00137.1 - 2.8e-07 30.3 0.4 2.8e-07 30.3 0.3 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EMD00137.1 - 0.014 14.8 0.2 0.014 14.8 0.1 2.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 EMD00137.1 - 0.035 13.3 1.4 0.18 11.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 EMD00137.1 - 0.089 12.2 0.3 0.089 12.2 0.2 2.8 3 0 0 3 3 3 0 A2L zinc ribbon domain RPN7 PF10602.4 EMD00138.1 - 3.3e-53 179.6 0.6 3.3e-53 179.6 0.4 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EMD00138.1 - 2.5e-08 34.1 0.0 5.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EMD00138.1 - 0.0046 16.7 0.1 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD00138.1 - 0.02 15.2 1.2 0.062 13.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD00138.1 - 0.024 14.4 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD00138.1 - 0.051 14.2 0.0 0.27 12.0 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat SSFA2_C PF14723.1 EMD00138.1 - 4 7.1 5.3 8.9 6.0 3.7 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Pox_MCEL PF03291.11 EMD00139.1 - 1.1e-63 215.1 0.0 3e-43 147.9 0.0 2.8 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EMD00139.1 - 0.00019 21.8 0.0 0.001 19.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD00139.1 - 0.00043 19.8 0.0 0.0014 18.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD00139.1 - 0.00063 20.1 0.0 0.4 11.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EMD00139.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain BSP_II PF05432.6 EMD00139.1 - 0.019 14.2 5.2 0.034 13.4 3.6 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Methyltransf_25 PF13649.1 EMD00139.1 - 0.058 13.7 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EMD00140.1 - 3.2e-20 72.7 5.9 1.2e-18 67.6 4.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD00140.1 - 3.1e-12 46.7 1.5 2.6e-11 43.7 1.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD00140.1 - 1.6e-09 37.7 0.6 1.6e-09 37.7 0.5 2.0 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EMD00140.1 - 0.00077 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EMD00140.1 - 0.0015 18.5 0.2 0.0029 17.6 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EMD00140.1 - 0.0018 17.7 0.5 0.0059 16.0 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EMD00140.1 - 0.0038 16.7 0.3 0.006 16.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EMD00140.1 - 0.033 13.1 0.1 0.048 12.6 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EMD00140.1 - 0.039 12.6 0.1 0.066 11.9 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EMD00140.1 - 0.068 13.2 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvGEDA_leader PF08046.6 EMD00143.1 - 0.88 8.7 1.8 1.4 8.0 1.3 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide DUF21 PF01595.15 EMD00144.1 - 1.2e-33 115.9 2.2 1.8e-33 115.3 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 EMD00144.1 - 8.7e-07 28.6 0.3 0.053 13.3 0.0 2.8 2 0 0 2 2 2 2 CBS domain DUF4567 PF15131.1 EMD00145.1 - 0.05 13.7 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) Vps51 PF08700.6 EMD00146.1 - 2.4e-27 94.6 0.0 4.9e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 EMD00146.1 - 0.0015 17.0 0.0 0.0018 16.7 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family HeLo PF14479.1 EMD00146.1 - 0.094 12.4 1.1 0.18 11.5 0.6 2.0 1 1 0 1 1 1 0 Prion-inhibition and propagation DUF1767 PF08585.7 EMD00147.1 - 2.3e-15 56.6 0.1 3.4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Abhydrolase_6 PF12697.2 EMD00149.1 - 4.8e-22 78.9 0.6 6.5e-22 78.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD00149.1 - 0.00031 20.5 0.0 0.00063 19.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMD00149.1 - 0.019 13.4 0.0 0.029 12.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.15 EMD00149.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 EMD00150.1 - 9.6e-12 44.6 0.2 2.2e-11 43.4 0.1 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.7 EMD00150.1 - 0.016 13.7 0.2 0.15 10.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 EMD00150.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMD00150.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EMD00150.1 - 0.081 12.3 0.1 0.17 11.2 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EMD00150.1 - 0.086 12.0 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 EMD00150.1 - 0.091 12.3 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 EMD00150.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.8 EMD00150.1 - 0.16 11.4 0.0 9.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EMD00150.1 - 0.18 11.2 0.0 0.55 9.6 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ribonuclease_T2 PF00445.13 EMD00151.1 - 8e-43 146.2 0.4 1.3e-42 145.6 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DNA_pol_A_exo1 PF01612.15 EMD00152.1 - 1.5e-41 141.7 0.4 2.4e-41 141.1 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EMD00152.1 - 3.6e-23 81.6 0.2 2.1e-22 79.2 0.1 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EMD00152.1 - 6.2e-15 54.6 0.0 2.6e-14 52.6 0.0 2.2 1 0 0 1 1 1 1 HRDC domain UPF0203 PF05254.7 EMD00153.1 - 5e-30 103.1 1.2 6e-30 102.9 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EMD00153.1 - 0.00067 19.6 0.4 0.0016 18.4 0.3 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EMD00153.1 - 0.0013 18.4 3.0 0.095 12.4 0.1 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EMD00153.1 - 0.086 12.7 1.5 2.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein F-box-like_2 PF13013.1 EMD00154.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain ECH PF00378.15 EMD00155.1 - 2.7e-50 170.8 0.0 3.3e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GAD-like PF08887.6 EMD00156.1 - 0.12 12.4 0.0 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 GAD-like domain Metallothio_11 PF02066.10 EMD00157.1 - 0.19 11.6 0.3 0.19 11.6 0.2 1.6 2 0 0 2 2 2 0 Metallothionein family 11 HATPase_c PF02518.21 EMD00158.1 - 2.1e-19 69.2 0.1 4.8e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD00158.1 - 4e-18 65.4 0.0 2.1e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMD00158.1 - 6.7e-13 48.4 0.0 2.6e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EMD00158.1 - 6.8e-08 32.7 0.4 6.9e-07 29.5 0.0 2.7 3 0 0 3 3 3 1 GAF domain GAF_3 PF13492.1 EMD00158.1 - 7.3e-08 32.5 0.0 0.0006 19.9 0.0 3.1 2 1 0 2 2 2 2 GAF domain Apt1 PF10351.4 EMD00158.1 - 0.037 12.8 2.1 0.071 11.9 1.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Methyltransf_26 PF13659.1 EMD00160.1 - 3.8e-17 62.4 0.4 5.8e-17 61.8 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD00160.1 - 0.066 12.9 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMD00160.1 - 0.076 12.3 0.0 0.29 10.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_42 PF02449.10 EMD00161.1 - 1.2e-09 37.7 0.0 2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 EMD00161.1 - 1.7e-07 30.9 0.0 1.4e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 EMD00161.1 - 0.03 13.3 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 FAA_hydrolase_N PF09298.6 EMD00161.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Cellulase PF00150.13 EMD00162.1 - 1.9e-08 33.8 5.8 6.9e-07 28.7 0.7 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EMD00162.1 - 0.0003 20.0 1.5 0.046 12.8 0.3 2.3 2 0 0 2 2 2 2 Beta-galactosidase DnaJ PF00226.26 EMD00163.1 - 4e-24 84.1 1.4 1.6e-23 82.2 1.0 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 EMD00163.1 - 5.9e-19 67.4 13.9 5e-10 38.8 0.3 4.8 4 2 3 7 7 7 4 TPR repeat TPR_1 PF00515.23 EMD00163.1 - 8.4e-18 63.1 10.6 0.0018 17.8 0.7 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMD00163.1 - 4.5e-14 51.1 17.5 0.0029 17.4 0.1 7.1 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD00163.1 - 4.4e-12 46.3 5.7 2.7e-05 24.7 0.9 5.6 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD00163.1 - 1.2e-10 41.0 11.2 0.053 14.1 0.2 7.2 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD00163.1 - 3.4e-10 40.0 13.0 0.00015 22.0 0.5 5.2 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD00163.1 - 4.1e-10 38.7 5.2 0.032 13.9 0.3 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMD00163.1 - 1.1e-08 34.7 0.6 0.0041 16.9 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD00163.1 - 1.8e-07 30.9 12.0 0.0011 18.7 1.0 4.7 4 2 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD00163.1 - 1.3e-05 25.2 6.7 0.0045 17.0 0.8 4.0 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMD00163.1 - 0.00036 20.1 3.5 1.6 8.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD00163.1 - 0.0013 19.0 15.5 1.4 9.5 0.1 7.2 8 1 0 8 8 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD00163.1 - 0.003 17.3 5.4 0.86 9.5 0.0 4.5 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat SHOCT PF09851.4 EMD00163.1 - 0.027 13.9 0.4 5.7 6.5 0.2 3.1 2 0 0 2 2 2 0 Short C-terminal domain TPR_17 PF13431.1 EMD00163.1 - 0.033 14.3 0.1 0.033 14.3 0.1 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat YfdX PF10938.3 EMD00163.1 - 0.13 11.8 11.8 0.21 11.2 0.2 3.9 3 1 0 4 4 4 0 YfdX protein TPR_10 PF13374.1 EMD00163.1 - 0.51 10.3 12.2 2.5 8.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Xpo1 PF08389.7 EMD00164.1 - 2.6e-06 27.4 1.0 0.00011 22.0 0.0 3.7 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EMD00164.1 - 0.072 13.0 3.3 0.15 11.9 0.2 3.2 4 0 0 4 4 4 0 Importin-beta N-terminal domain zf-C2H2_4 PF13894.1 EMD00166.1 - 2.1e-05 24.5 3.9 0.0099 16.1 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD00166.1 - 0.0021 18.3 3.9 0.29 11.5 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-TFIIB PF13453.1 EMD00166.1 - 0.067 12.3 0.3 0.14 11.3 0.2 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Ribosomal_L35p PF01632.14 EMD00166.1 - 0.25 11.2 0.7 8.7 6.3 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L35 zf-C2H2_6 PF13912.1 EMD00166.1 - 0.31 10.9 2.7 13 5.8 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_EFTU PF00009.22 EMD00167.1 - 2.5e-09 36.8 0.0 1.1e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EMD00167.1 - 0.011 15.8 0.1 0.041 13.9 0.1 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Miro PF08477.8 EMD00167.1 - 0.18 12.2 0.4 1.2 9.6 0.0 2.5 3 0 0 3 3 3 0 Miro-like protein Hint_2 PF13403.1 EMD00168.1 - 0.06 13.2 1.0 0.73 9.7 0.0 2.7 3 0 0 3 3 3 0 Hint domain Apc1 PF12859.2 EMD00169.1 - 7.9e-20 71.0 0.0 2.7e-19 69.3 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EMD00169.1 - 3.7 7.9 9.2 0.77 10.1 0.2 4.1 4 0 0 4 4 4 0 Proteasome/cyclosome repeat Ribosomal_L31 PF01197.13 EMD00170.1 - 0.0011 18.9 0.1 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L31 Flavin_Reduct PF01613.13 EMD00171.1 - 1.5e-21 76.8 0.4 7.4e-21 74.6 0.0 2.3 3 0 0 3 3 3 1 Flavin reductase like domain KH_1 PF00013.24 EMD00171.1 - 9.2e-12 44.4 0.0 0.0021 17.6 0.0 5.0 5 0 0 5 5 5 3 KH domain KH_3 PF13014.1 EMD00171.1 - 2.7e-05 23.6 0.0 0.14 11.8 0.0 4.2 4 0 0 4 4 4 2 KH domain SHOCT PF09851.4 EMD00171.1 - 0.42 10.1 4.7 0.18 11.2 0.7 2.4 2 0 0 2 2 2 0 Short C-terminal domain Formyl_trans_N PF00551.14 EMD00172.1 - 1.8e-14 53.7 0.0 1.2e-13 50.9 0.0 2.3 1 1 0 1 1 1 1 Formyl transferase ECH PF00378.15 EMD00172.1 - 1.2e-12 47.4 0.0 2.2e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_C PF02911.13 EMD00172.1 - 0.00028 20.9 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain SpoIIAA-like PF11964.3 EMD00172.1 - 0.019 15.2 0.3 0.063 13.5 0.0 2.0 2 0 0 2 2 2 0 SpoIIAA-like PDCD2_C PF04194.8 EMD00173.1 - 1.6e-51 174.1 0.0 2.6e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain DUF3113 PF11310.3 EMD00173.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) MCR_beta PF02241.13 EMD00175.1 - 0.059 12.5 0.3 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain SnoaL PF07366.7 EMD00176.1 - 2.8e-12 46.3 0.0 3.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMD00176.1 - 1.1e-07 32.2 0.0 1.5e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SH3_5 PF08460.5 EMD00176.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain BTB PF00651.26 EMD00177.1 - 1.5e-05 24.9 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Med11 PF10280.4 EMD00178.1 - 1e-16 61.0 0.0 2.3e-16 59.9 0.0 1.5 1 1 0 1 1 1 1 Mediator complex protein WD40 PF00400.27 EMD00179.1 - 2.6e-53 176.1 20.4 4.4e-10 39.0 0.8 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EMD00179.1 - 8e-43 145.9 0.1 1.2e-42 145.3 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 EMD00179.1 - 0.0027 17.4 0.1 0.35 10.5 0.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Trigger_C PF05698.9 EMD00179.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Nucleoporin_N PF08801.6 EMD00179.1 - 0.19 10.4 0.5 3.4 6.3 0.0 2.7 2 2 0 2 2 2 0 Nup133 N terminal like CheZ PF04344.8 EMD00180.1 - 0.00061 19.5 0.5 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ APG17 PF04108.7 EMD00180.1 - 0.0036 16.1 0.6 0.055 12.2 0.2 2.0 1 1 1 2 2 2 1 Autophagy protein Apg17 BLOC1_2 PF10046.4 EMD00180.1 - 0.0064 16.6 0.2 4.5 7.4 0.1 3.0 3 1 0 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EMD00180.1 - 0.012 15.2 0.3 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 IncA protein LXG PF04740.7 EMD00180.1 - 0.022 14.5 0.1 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily DRIM PF07539.7 EMD00180.1 - 0.081 12.3 0.4 7.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Down-regulated in metastasis D-ser_dehydrat PF14031.1 EMD00182.1 - 2.7e-20 72.3 0.0 5.2e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EMD00182.1 - 1.3e-14 54.2 0.1 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA_m1G_MT PF01746.16 EMD00184.1 - 9.3e-35 119.8 0.1 3.8e-26 91.8 0.0 2.3 1 1 1 2 2 2 2 tRNA (Guanine-1)-methyltransferase GRIM-19 PF06212.7 EMD00185.1 - 1.5e-07 31.1 0.2 3.3e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein DUF4185 PF13810.1 EMD00186.1 - 1.1e-05 24.4 0.1 1.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Mito_carr PF00153.22 EMD00188.1 - 5e-74 244.1 4.2 2.5e-24 84.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_47 PF01532.15 EMD00189.1 - 1.2e-146 488.9 0.0 6.1e-78 262.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 tRNA-synt_2 PF00152.15 EMD00190.1 - 2e-70 237.2 0.0 2.7e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMD00190.1 - 1.3e-06 28.1 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMD00190.1 - 0.0077 15.4 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) AAA PF00004.24 EMD00191.1 - 4.6e-38 130.4 0.0 8.8e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMD00191.1 - 6.2e-07 29.2 0.0 0.00013 21.7 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EMD00191.1 - 7.8e-06 26.0 0.0 0.00023 21.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMD00191.1 - 9.9e-05 21.4 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EMD00191.1 - 0.00064 18.5 0.1 0.0011 17.8 0.1 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EMD00191.1 - 0.0011 19.0 2.1 0.024 14.6 0.0 3.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 EMD00191.1 - 0.0012 18.5 0.0 0.0037 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EMD00191.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMD00191.1 - 0.0037 16.4 0.1 0.007 15.5 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMD00191.1 - 0.0059 16.3 0.0 0.023 14.4 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EMD00191.1 - 0.0062 16.2 0.0 0.066 12.8 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 EMD00191.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD00191.1 - 0.0088 15.9 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMD00191.1 - 0.0097 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EMD00191.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EMD00191.1 - 0.013 14.9 0.1 0.25 10.7 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EMD00191.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EMD00191.1 - 0.043 13.3 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMD00191.1 - 0.044 14.6 0.8 0.14 13.0 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EMD00191.1 - 0.071 13.0 2.6 0.18 11.7 0.0 2.9 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 EMD00191.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EMD00191.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EMD00191.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.16 EMD00191.1 - 0.21 10.9 0.0 0.53 9.7 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.21 EMD00191.1 - 0.22 10.9 0.0 0.49 9.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain eIF-3c_N PF05470.7 EMD00191.1 - 6.9 4.6 8.7 0.61 8.1 0.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SYS1 PF09801.4 EMD00193.1 - 7.4e-50 168.7 11.9 8.4e-50 168.5 8.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF3270 PF11674.3 EMD00193.1 - 3.2 7.8 5.0 0.59 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Tim17 PF02466.14 EMD00194.1 - 1.1e-07 31.9 10.0 1.6e-07 31.3 6.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TBCC PF07986.7 EMD00195.1 - 1.9e-28 98.2 0.0 2.8e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C UCH PF00443.24 EMD00196.1 - 6.8e-33 113.9 0.0 1.5e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EMD00196.1 - 1.3e-21 75.7 0.8 2.7e-07 29.8 0.0 4.9 5 0 0 5 5 5 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EMD00196.1 - 3.1e-12 46.5 0.1 6.6e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Osmo_CC PF08946.5 EMD00196.1 - 0.044 13.7 0.9 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil KGG PF10685.4 EMD00198.1 - 8.3e-08 31.9 1.9 1.2e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 Stress-induced bacterial acidophilic repeat motif Tannase PF07519.6 EMD00199.1 - 1.6e-101 340.3 0.1 1.9e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EMD00199.1 - 4.8e-08 33.1 0.0 2.2e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD00199.1 - 0.00022 20.4 0.0 0.045 12.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD00199.1 - 0.0062 16.3 0.6 0.33 10.7 0.0 2.6 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD00199.1 - 0.019 14.5 0.0 0.019 14.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Antimicrobial17 PF08129.6 EMD00199.1 - 0.17 11.6 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta enterocin family Esterase PF00756.15 EMD00199.1 - 0.2 11.0 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Glyco_hydro_47 PF01532.15 EMD00200.1 - 2.1e-177 590.3 0.0 4.1e-177 589.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Gln-synt_C PF00120.19 EMD00203.1 - 1.2e-46 158.9 0.0 1.9e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EMD00203.1 - 1.2e-26 93.8 0.0 2.4e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Fib_alpha PF08702.5 EMD00203.1 - 0.13 12.3 0.2 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family adh_short PF00106.20 EMD00204.1 - 1.4e-10 41.3 0.0 2.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMD00204.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD00204.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HRXXH PF13933.1 EMD00206.1 - 0.034 13.5 0.4 0.042 13.2 0.3 1.1 1 0 0 1 1 1 0 Putative peptidase family DZR PF12773.2 EMD00206.1 - 0.51 10.2 4.9 1.3 8.9 3.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon Complex1_LYR PF05347.10 EMD00207.1 - 0.0027 17.4 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EMD00207.1 - 0.0044 17.4 0.1 0.0066 16.9 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EMD00207.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like PMT_C PF11647.3 EMD00207.1 - 0.15 11.6 0.1 0.7 9.5 0.1 1.9 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 NAD_binding_10 PF13460.1 EMD00208.1 - 4.4e-20 72.4 0.0 5.4e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMD00208.1 - 1.5e-11 44.0 0.3 3.8e-11 42.6 0.1 1.8 2 1 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EMD00208.1 - 9.3e-09 35.0 0.0 2.4e-08 33.7 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMD00208.1 - 0.00086 19.2 0.0 0.092 12.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMD00208.1 - 0.0014 17.5 0.1 0.33 9.8 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EMD00208.1 - 0.0023 16.6 0.0 0.0032 16.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMD00208.1 - 0.051 13.2 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 KR domain Saccharop_dh PF03435.13 EMD00208.1 - 0.09 11.7 0.1 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase GST_N_3 PF13417.1 EMD00209.1 - 2.1e-28 98.3 0.2 7.7e-28 96.5 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD00209.1 - 7e-19 67.6 0.2 6.3e-18 64.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD00209.1 - 1.8e-09 37.5 0.0 3.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD00209.1 - 2.3e-08 33.7 0.0 7.3e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD00209.1 - 0.00017 22.0 0.1 0.00047 20.5 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EMD00209.1 - 0.0066 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 EMD00209.1 - 0.0077 16.1 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SPX PF03105.14 EMD00210.1 - 8.5e-29 101.1 0.3 1.4e-28 100.5 0.2 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EMD00210.1 - 0.0014 18.4 12.2 0.0028 17.5 7.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMD00210.1 - 0.0065 16.1 10.5 0.013 15.0 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD00210.1 - 0.0086 16.0 12.8 0.017 15.1 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EMD00210.1 - 0.02 14.6 5.1 0.043 13.5 3.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4501 PF14946.1 EMD00210.1 - 0.024 14.1 1.8 0.037 13.4 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) zf-C3HC4_3 PF13920.1 EMD00210.1 - 0.098 12.3 10.2 0.16 11.6 7.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EMD00210.1 - 1.2 8.9 6.5 3.3 7.5 4.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon Rep_fac-A_C PF08646.5 EMD00210.1 - 1.6 8.4 8.6 0.17 11.5 1.5 2.7 3 1 0 3 3 3 0 Replication factor-A C terminal domain zf-RING_4 PF14570.1 EMD00210.1 - 8.3 6.0 10.5 24 4.5 7.3 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DnaJ PF00226.26 EMD00211.1 - 8.3e-26 89.5 0.7 8.3e-26 89.5 0.5 2.7 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.3 EMD00211.1 - 1.7e-11 43.8 2.5 1.7e-11 43.8 1.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD00211.1 - 2.1e-08 34.0 5.4 5.2e-08 32.8 1.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMD00211.1 - 7.9e-06 25.9 3.6 0.0035 17.4 0.6 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EMD00211.1 - 0.00016 21.8 6.0 0.03 14.6 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD00211.1 - 0.00085 19.4 7.0 0.24 11.7 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger AKAP95 PF04988.7 EMD00211.1 - 0.066 12.9 2.2 0.6 9.8 0.5 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 EMD00211.1 - 2.4 8.1 4.4 2.3 8.2 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Lipoprotein_16 PF03923.8 EMD00212.1 - 0.13 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized lipoprotein JAB PF01398.16 EMD00213.1 - 5e-14 52.0 0.0 8.7e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EMD00213.1 - 1.1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EMD00213.1 - 5.2e-06 25.9 0.1 1.4e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HAUS6_N PF14661.1 EMD00213.1 - 0.072 12.4 0.4 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spc24 PF08286.6 EMD00213.1 - 0.1 12.3 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1744 PF08490.7 EMD00215.1 - 1.1e-142 475.3 0.1 1.5e-142 474.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EMD00215.1 - 3.6e-66 223.2 0.0 2.6e-64 217.1 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EMD00215.1 - 2.8e-22 79.1 0.2 6.5e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EMD00215.1 - 8.4e-11 41.7 0.0 2.2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EMD00215.1 - 4e-05 23.4 0.0 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 1 RNase_H superfamily zf-DNA_Pol PF08996.5 EMD00215.1 - 0.12 11.7 4.2 0.25 10.6 2.9 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF3767 PF12597.3 EMD00216.1 - 1.6e-29 102.0 0.6 2.3e-29 101.4 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DivIVA PF05103.8 EMD00218.1 - 0.017 15.1 4.4 0.02 14.9 3.1 1.1 1 0 0 1 1 1 0 DivIVA protein DUF883 PF05957.8 EMD00218.1 - 0.098 13.0 7.9 0.23 11.8 2.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Methyltransf_32 PF13679.1 EMD00218.1 - 0.098 12.3 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain ISG65-75 PF11727.3 EMD00218.1 - 0.16 10.9 4.4 0.18 10.8 3.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Borrelia_P83 PF05262.6 EMD00218.1 - 0.27 9.4 4.2 0.27 9.4 2.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Aldedh PF00171.17 EMD00221.1 - 1.4e-153 511.6 0.1 1.5e-153 511.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_11 PF14833.1 EMD00221.1 - 0.018 15.1 0.4 0.76 9.8 0.0 2.5 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PrkA PF06798.7 EMD00221.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain TPP_enzyme_N PF02776.13 EMD00222.1 - 5.2e-36 123.7 1.8 2.3e-33 115.0 0.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMD00222.1 - 1.6e-18 66.7 0.3 5.3e-18 65.0 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMD00222.1 - 1.5e-17 63.6 0.0 3.3e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pkinase PF00069.20 EMD00223.1 - 4.6e-62 209.5 0.0 6.9e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD00223.1 - 8.7e-41 139.7 0.0 1.4e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD00223.1 - 7.3e-10 38.2 0.0 1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EMD00223.1 - 0.045 12.8 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IpgD PF05925.7 EMD00223.1 - 0.077 11.2 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Rsa3 PF14615.1 EMD00224.1 - 1.3e-17 62.7 0.1 2.1e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 E_Pc_C PF06752.7 EMD00224.1 - 0.053 13.0 0.5 0.067 12.6 0.4 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus SurE PF01975.12 EMD00228.1 - 2.5e-28 98.7 0.1 3.3e-28 98.3 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE DIM PF08194.7 EMD00228.1 - 0.0014 18.5 1.5 0.0032 17.3 1.0 1.6 1 0 0 1 1 1 1 DIM protein Aconitase PF00330.15 EMD00229.1 - 5.9e-176 585.5 0.0 1.7e-175 583.9 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMD00229.1 - 3.1e-47 159.9 0.0 5.2e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EMD00229.1 - 0.14 10.6 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) zf-C2H2_jaz PF12171.3 EMD00230.1 - 7.1e-09 35.5 1.6 7.1e-09 35.5 1.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD00230.1 - 0.0038 17.3 0.7 0.0038 17.3 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMD00230.1 - 0.011 15.5 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4188 PF13826.1 EMD00230.1 - 0.038 14.0 0.9 1.8 8.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) zf-C2H2_4 PF13894.1 EMD00230.1 - 0.062 13.6 0.1 0.062 13.6 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMD00230.1 - 0.068 13.2 4.4 0.3 11.2 3.0 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Hexapep PF00132.19 EMD00231.1 - 1.2e-10 40.3 14.1 4.2e-07 29.1 4.2 3.2 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMD00231.1 - 4.9e-09 35.5 10.2 3.3e-08 32.9 4.1 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DnaJ PF00226.26 EMD00232.1 - 3.5e-09 36.2 0.5 3.5e-09 36.2 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain Phasin PF05597.6 EMD00232.1 - 0.0028 17.4 0.0 0.0057 16.4 0.0 1.5 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) UPF0242 PF06785.6 EMD00232.1 - 0.04 12.6 0.1 0.15 10.7 0.1 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) Phage_lysis PF03245.8 EMD00232.1 - 0.1 12.5 1.2 0.25 11.3 0.3 1.9 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein SlyX PF04102.7 EMD00232.1 - 0.21 11.9 2.9 5.5 7.4 0.1 2.6 1 1 0 2 2 2 0 SlyX Pro-kuma_activ PF09286.6 EMD00234.1 - 9e-38 129.5 0.7 6.1e-37 126.8 0.5 2.3 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMD00234.1 - 1.7e-06 27.4 0.0 3.6e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Subtilase family Lactamase_B PF00753.22 EMD00235.1 - 8.8e-25 87.4 0.6 1.2e-24 87.0 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD00235.1 - 4.8e-07 29.5 0.1 2.6e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMD00235.1 - 0.001 18.7 0.1 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ketoacyl-synt PF00109.21 EMD00236.1 - 4.7e-76 255.6 0.0 1.3e-75 254.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD00236.1 - 1.5e-50 172.3 0.0 3.4e-50 171.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMD00236.1 - 1.7e-33 114.9 3.2 5.7e-33 113.2 2.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMD00236.1 - 1.7e-24 85.8 4.7 3.7e-12 46.3 0.3 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EMD00236.1 - 6.5e-16 58.3 0.0 1.6e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EMD00236.1 - 6.3e-05 22.0 0.0 0.00018 20.5 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain EcoRII-N PF09217.5 EMD00237.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal NAD_binding_10 PF13460.1 EMD00239.1 - 2e-17 63.7 0.0 3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMD00239.1 - 0.0026 17.0 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAPRTase PF04095.11 EMD00239.1 - 0.065 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family RecX PF02631.11 EMD00239.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 RecX family Zn_clus PF00172.13 EMD00242.1 - 4.2e-08 32.9 13.4 1e-07 31.7 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EMD00242.1 - 1.7e-05 24.8 24.3 0.00011 22.3 1.1 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD00242.1 - 0.00034 20.7 1.5 0.00034 20.7 1.0 4.3 3 1 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD00242.1 - 0.0011 19.1 4.0 0.0011 19.1 2.8 4.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMD00242.1 - 0.6 10.3 5.1 11 6.3 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.20 EMD00244.1 - 3.7e-29 101.7 1.3 5.3e-29 101.2 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD00244.1 - 8.7e-28 97.6 0.1 1.1e-27 97.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD00244.1 - 1.2e-14 54.3 0.5 1.7e-14 53.8 0.4 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMD00244.1 - 0.035 13.7 1.7 0.052 13.2 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 EMD00244.1 - 0.047 13.2 3.2 0.11 12.1 2.2 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein QRPTase_C PF01729.14 EMD00246.1 - 9e-54 181.5 0.0 1.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EMD00246.1 - 8.3e-25 86.4 0.1 2.2e-24 85.0 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Peripla_BP_4 PF13407.1 EMD00246.1 - 0.011 15.1 0.0 0.12 11.7 0.0 1.9 1 1 1 2 2 2 0 Periplasmic binding protein domain PTS_IIB PF02302.12 EMD00246.1 - 0.085 13.3 0.5 0.18 12.2 0.4 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Prenylcys_lyase PF07156.9 EMD00247.1 - 1.8e-35 122.5 0.0 3.8e-35 121.4 0.0 1.4 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EMD00247.1 - 1.8e-12 47.1 0.3 4.4e-12 45.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMD00247.1 - 1.5e-08 34.1 0.0 1.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMD00247.1 - 1.3e-07 30.8 1.1 1.6e-06 27.3 0.7 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD00247.1 - 8.2e-05 22.4 0.1 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMD00247.1 - 0.0059 16.6 0.3 0.033 14.2 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD00247.1 - 0.019 14.8 0.5 0.045 13.6 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD00247.1 - 0.022 13.8 0.7 0.076 12.1 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 EMD00247.1 - 0.058 13.5 0.0 0.42 10.7 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EMD00247.1 - 0.081 11.7 0.8 0.12 11.1 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EMD00247.1 - 0.089 13.2 0.2 1.2 9.5 0.1 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMD00247.1 - 0.096 12.1 0.2 0.21 11.0 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 EMD00247.1 - 0.19 10.8 1.9 6.7 5.6 0.8 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HTH_18 PF12833.2 EMD00249.1 - 0.058 13.5 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GTP_EFTU PF00009.22 EMD00250.1 - 3.5e-40 137.4 2.4 2.2e-39 134.8 1.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMD00250.1 - 4.8e-24 84.3 0.1 1.3e-23 82.9 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMD00250.1 - 1.8e-14 53.5 2.6 1.5e-06 28.1 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMD00250.1 - 2.1e-07 30.9 0.1 7.5e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 EMD00250.1 - 5.1e-06 25.8 0.0 9.4e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMD00250.1 - 2.5e-05 24.7 0.0 6.4e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EMD00250.1 - 3.6e-05 22.6 0.8 0.00012 20.9 0.6 2.0 1 0 0 1 1 1 1 ArgK protein FeoB_N PF02421.13 EMD00250.1 - 4.8e-05 22.6 0.3 0.00013 21.2 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EMD00250.1 - 9.1e-05 21.9 0.3 0.00026 20.4 0.2 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IF2_N PF04760.10 EMD00250.1 - 0.00045 19.8 0.0 0.0014 18.1 0.0 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Ras PF00071.17 EMD00250.1 - 0.0042 16.4 0.1 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMD00250.1 - 0.012 14.7 0.0 0.028 13.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MutL_C PF08676.6 EMD00250.1 - 0.025 14.1 0.6 0.46 10.0 0.0 3.0 3 0 0 3 3 3 0 MutL C terminal dimerisation domain DDRGK PF09756.4 EMD00250.1 - 1.1 8.6 26.4 0.07 12.5 7.2 2.7 2 0 0 2 2 2 0 DDRGK domain SAPS PF04499.10 EMD00250.1 - 2.1 6.8 9.3 0.23 10.0 2.1 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein MFS_1 PF07690.11 EMD00251.1 - 7e-26 90.7 37.8 8.5e-26 90.4 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C12 PF01088.16 EMD00252.1 - 4.8e-54 182.7 0.0 2.1e-39 134.9 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 Herpes_UL36 PF03586.8 EMD00252.1 - 0.013 14.6 0.6 0.37 9.8 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein DEAD PF00270.24 EMD00254.1 - 1.5e-41 141.7 0.2 2.1e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD00254.1 - 1.8e-23 82.1 0.1 3.5e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EMD00254.1 - 0.034 13.2 0.1 0.075 12.0 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GRP PF07172.6 EMD00254.1 - 0.13 12.7 17.5 0.22 11.9 12.1 1.4 1 0 0 1 1 1 0 Glycine rich protein family SieB PF14163.1 EMD00254.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B Rhomboid PF01694.17 EMD00255.1 - 1.5e-17 63.9 16.1 3.8e-17 62.6 11.1 1.6 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 EMD00255.1 - 0.021 15.1 1.1 0.04 14.2 0.3 1.8 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Ureidogly_hydro PF04115.7 EMD00256.1 - 2.7e-53 179.7 0.0 3.4e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Acetyltransf_13 PF13880.1 EMD00257.1 - 1.6e-18 66.1 0.0 4.8e-18 64.6 0.0 1.8 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EMD00257.1 - 1.3e-12 47.0 0.5 2.1e-12 46.4 0.4 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EMD00257.1 - 0.08 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DNA_RNApol_7kD PF03604.8 EMD00257.1 - 0.13 11.7 0.1 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit COesterase PF00135.23 EMD00258.1 - 3.4e-85 286.7 0.5 4.2e-85 286.4 0.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD00258.1 - 3.4e-08 33.3 0.1 1.4e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PEMT PF04191.8 EMD00258.1 - 0.044 13.8 0.4 3.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Phospholipid methyltransferase Peptidase_S9 PF00326.16 EMD00258.1 - 0.049 12.8 0.8 0.12 11.5 0.6 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family RPE65 PF03055.10 EMD00259.1 - 3.7e-106 355.5 0.0 4.4e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Peptidase_C14 PF00656.17 EMD00260.1 - 7.1e-71 238.7 0.0 9.2e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain DUF4051 PF13260.1 EMD00261.1 - 0.14 11.5 0.2 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) HNH PF01844.18 EMD00262.1 - 7.1e-05 22.5 1.4 0.00016 21.4 1.0 1.6 1 1 0 1 1 1 1 HNH endonuclease DUF968 PF06147.6 EMD00262.1 - 0.042 13.7 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF968) C1_1 PF00130.17 EMD00262.1 - 0.055 13.2 0.5 0.11 12.2 0.4 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HAD_2 PF13419.1 EMD00263.1 - 2.7e-22 79.8 0.0 4.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD00263.1 - 2.3e-05 23.9 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMD00263.1 - 0.032 14.6 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aa_trans PF01490.13 EMD00264.1 - 2.9e-51 174.2 38.5 3.4e-51 174.0 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMD00264.1 - 0.0065 15.0 51.7 0.23 9.9 35.8 2.3 1 1 0 1 1 1 1 Amino acid permease CAAD PF14159.1 EMD00264.1 - 0.33 10.6 10.8 0.032 13.8 1.3 3.5 2 1 1 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase CBS PF00571.23 EMD00265.1 - 2.6e-41 139.1 6.2 1.6e-10 40.5 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EMD00265.1 - 2e-11 43.4 0.0 8.8e-11 41.3 0.0 2.2 2 1 0 2 2 2 1 PB1 domain Imm1 PF14430.1 EMD00265.1 - 0.054 13.6 0.2 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm1 DUF3235 PF11574.3 EMD00265.1 - 0.16 12.2 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Mitofilin PF09731.4 EMD00265.1 - 0.23 10.0 7.1 1.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial inner membrane protein Ribosomal_S26e PF01283.14 EMD00266.1 - 1e-50 170.7 8.9 1.2e-50 170.5 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EMD00266.1 - 0.042 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 EMD00266.1 - 0.056 13.7 0.2 9.2 6.6 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EMD00266.1 - 0.1 12.9 1.5 1.7 9.0 0.3 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain VanZ PF04892.7 EMD00267.1 - 5e-13 49.1 0.5 6.5e-13 48.7 0.4 1.2 1 0 0 1 1 1 1 VanZ like family RseC_MucC PF04246.7 EMD00267.1 - 0.23 11.0 0.8 1.5 8.3 0.0 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.1 EMD00267.1 - 9.1 5.6 11.0 6 6.2 1.8 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Bromodomain PF00439.20 EMD00268.1 - 2.9e-18 65.5 0.4 6.5e-18 64.4 0.3 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EMD00268.1 - 0.00024 20.7 0.0 0.00081 19.0 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated Sec_GG PF07549.9 EMD00269.1 - 0.083 12.1 1.1 0.17 11.1 0.8 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif ubiquitin PF00240.18 EMD00270.1 - 6.8e-12 44.6 0.0 1.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.11 EMD00270.1 - 5e-10 39.0 10.7 8.3e-10 38.3 7.4 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 EMD00270.1 - 1.5e-05 24.5 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMD00270.1 - 0.0047 17.1 0.0 0.0072 16.4 0.0 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 EMD00270.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Telomere stability and silencing DUF4187 PF13821.1 EMD00270.1 - 0.4 10.3 3.2 0.85 9.2 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Chitin_bind_1 PF00187.14 EMD00272.1 - 2.8e-08 33.5 24.9 4e-08 33.1 17.2 1.4 1 1 0 1 1 1 1 Chitin recognition protein OTU PF02338.14 EMD00273.1 - 2.2e-11 44.4 0.0 3.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EMD00273.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 PB1 PF00564.19 EMD00273.1 - 0.056 13.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 PB1 domain ubiquitin PF00240.18 EMD00273.1 - 0.17 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Bromodomain PF00439.20 EMD00274.1 - 2.3e-35 120.3 4.7 4.9e-18 64.8 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EMD00274.1 - 1e-15 57.5 0.3 2.3e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 BAH domain PAT1 PF09770.4 EMD00274.1 - 6.6 4.8 18.1 10 4.1 12.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NAD_binding_8 PF13450.1 EMD00275.1 - 1.1e-08 34.9 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EMD00275.1 - 2.4e-08 32.6 0.0 2.6e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 EMD00275.1 - 3.2e-06 26.2 0.0 3.2e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMD00275.1 - 4e-06 26.1 0.0 5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EMD00275.1 - 1.1e-05 25.2 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMD00275.1 - 3.1e-05 24.1 0.0 4e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD00275.1 - 0.00027 20.8 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD00275.1 - 0.0011 19.2 0.1 0.0018 18.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD00275.1 - 0.0016 17.5 0.6 0.0023 17.0 0.4 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EMD00275.1 - 0.0017 17.2 0.1 0.002 17.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EMD00275.1 - 0.0025 16.7 0.1 0.0037 16.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EMD00275.1 - 0.017 13.5 0.7 0.015 13.7 0.4 1.3 1 1 0 1 1 1 0 HI0933-like protein Strep_67kDa_ant PF06100.6 EMD00275.1 - 0.022 13.1 0.1 0.032 12.5 0.1 1.2 1 1 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_binding_3 PF01494.14 EMD00275.1 - 0.045 12.8 0.1 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EMD00275.1 - 0.069 12.0 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EMD00275.1 - 0.069 12.7 0.1 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMD00275.1 - 0.083 12.8 0.3 0.12 12.3 0.1 1.4 2 0 0 2 2 2 0 NADH(P)-binding AAA PF00004.24 EMD00276.1 - 3.9e-45 153.2 0.4 9.9e-45 151.9 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD00276.1 - 2.4e-09 37.0 0.6 9.2e-09 35.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMD00276.1 - 4.2e-08 33.2 0.0 1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMD00276.1 - 4.6e-07 30.0 0.0 1.6e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD00276.1 - 1.4e-06 28.4 2.3 0.00028 21.0 0.5 3.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMD00276.1 - 3e-06 26.3 0.3 5.8e-06 25.4 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMD00276.1 - 0.00015 21.6 0.1 0.00082 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMD00276.1 - 0.00046 19.2 0.0 0.0012 17.9 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EMD00276.1 - 0.00048 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMD00276.1 - 0.00069 19.3 0.5 0.056 13.0 0.0 2.9 2 1 0 3 3 3 1 NACHT domain AAA_11 PF13086.1 EMD00276.1 - 0.00077 19.1 0.4 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMD00276.1 - 0.00093 19.3 0.0 0.0025 17.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EMD00276.1 - 0.0012 19.7 0.1 0.0055 17.5 0.0 2.1 3 0 0 3 3 1 1 AAA domain TIP49 PF06068.8 EMD00276.1 - 0.0012 17.6 0.0 0.0022 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Arch_ATPase PF01637.13 EMD00276.1 - 0.0014 18.3 1.3 0.079 12.6 0.0 2.9 2 1 0 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 EMD00276.1 - 0.0015 18.2 0.2 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EMD00276.1 - 0.002 17.8 0.0 0.0071 16.0 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.1 EMD00276.1 - 0.0035 16.9 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMD00276.1 - 0.0035 16.4 0.1 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 EMD00276.1 - 0.0039 16.8 0.0 0.013 15.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EMD00276.1 - 0.0043 17.4 2.2 1.2 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD00276.1 - 0.0048 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMD00276.1 - 0.0066 15.6 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EMD00276.1 - 0.011 15.3 0.2 0.03 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMD00276.1 - 0.011 15.1 0.4 0.03 13.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 EMD00276.1 - 0.019 14.4 3.6 0.059 12.7 0.0 2.8 2 1 1 3 3 3 0 AAA domain UPF0079 PF02367.12 EMD00276.1 - 0.02 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EMD00276.1 - 0.023 13.8 1.3 0.44 9.6 0.0 2.7 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.13 EMD00276.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 EMD00276.1 - 0.037 14.3 0.1 0.12 12.6 0.0 2.0 2 1 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 EMD00276.1 - 0.039 14.0 0.2 0.38 10.7 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EMD00276.1 - 0.04 13.3 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 EMD00276.1 - 0.066 11.4 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.17 EMD00276.1 - 0.13 11.1 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pyridoxal_deC PF00282.14 EMD00277.1 - 3e-77 259.5 0.0 3.7e-68 229.6 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EMD00277.1 - 5.6e-09 35.5 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase PUF PF00806.14 EMD00277.1 - 5.5e-07 28.7 0.0 4.5 6.9 0.0 5.7 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat Aminotran_5 PF00266.14 EMD00277.1 - 3.4e-05 22.7 0.0 6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 EMD00277.1 - 0.0071 14.8 0.0 0.012 14.0 0.0 1.3 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Cpn60_TCP1 PF00118.19 EMD00280.1 - 8.2e-143 476.5 5.1 9.5e-143 476.3 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family U3_assoc_6 PF08640.6 EMD00283.1 - 1.7e-22 78.9 0.2 7.2e-22 76.9 0.0 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EMD00283.1 - 0.0024 18.3 1.8 0.99 10.2 0.1 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 EMD00283.1 - 0.0071 16.1 0.0 0.26 11.0 0.0 2.5 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 EMD00283.1 - 0.029 13.2 0.1 0.22 10.3 0.0 2.2 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference MutL_C PF08676.6 EMD00284.1 - 0.029 13.9 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 MutL C terminal dimerisation domain YccV-like PF08755.6 EMD00285.1 - 1.9e-22 79.0 0.0 4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EMD00285.1 - 2.1e-11 43.5 0.0 3.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box PF00646.28 EMD00285.1 - 3.9e-05 23.1 0.0 7.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD00285.1 - 0.0002 21.0 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like CRAL_TRIO PF00650.15 EMD00286.1 - 1.8e-23 82.7 0.0 2.7e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMD00286.1 - 4.5e-08 33.0 0.0 1.5e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ifi-6-16 PF06140.8 EMD00287.1 - 0.026 14.3 0.3 0.053 13.3 0.2 1.5 1 0 0 1 1 1 0 Interferon-induced 6-16 family Glyco_hydro_16 PF00722.16 EMD00288.1 - 1.7e-09 37.2 1.4 2.2e-09 36.8 0.1 1.9 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 Prok-RING_2 PF14445.1 EMD00288.1 - 0.13 12.2 0.1 0.43 10.5 0.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 SAM_2 PF07647.12 EMD00289.1 - 2.1e-08 33.8 0.2 3.8e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMD00289.1 - 2.3e-05 24.4 0.1 5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3595 PF12166.3 EMD00289.1 - 0.15 10.8 0.2 0.22 10.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Microtub_assoc PF07989.6 EMD00291.1 - 3.1e-15 55.7 4.5 3.1e-15 55.7 3.1 2.1 1 1 1 2 2 2 1 Microtubule associated DUF310 PF03750.8 EMD00291.1 - 0.03 14.4 3.3 0.039 14.1 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF310) SRA1 PF07304.6 EMD00291.1 - 0.072 12.8 0.3 0.17 11.5 0.2 1.6 1 1 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Herpes_UL25 PF01499.11 EMD00291.1 - 0.084 11.1 5.4 0.094 11.0 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1090 PF06476.7 EMD00291.1 - 0.097 12.3 7.4 0.21 11.2 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) ATG16 PF08614.6 EMD00291.1 - 0.1 12.3 15.1 0.062 13.1 7.0 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 EMD00291.1 - 0.12 9.7 12.6 0.13 9.6 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 EMD00291.1 - 0.14 11.6 14.0 0.22 10.9 9.1 1.6 1 1 0 1 1 1 0 Intermediate filament protein Fzo_mitofusin PF04799.8 EMD00291.1 - 0.16 11.3 7.8 0.24 10.7 1.0 2.1 1 1 1 2 2 2 0 fzo-like conserved region Spore_III_AB PF09548.5 EMD00291.1 - 0.18 11.5 5.4 0.5 10.1 3.7 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Tropomyosin_1 PF12718.2 EMD00291.1 - 0.2 11.4 15.9 4.1 7.2 11.0 2.2 1 1 0 1 1 1 0 Tropomyosin like CCDC155 PF14662.1 EMD00291.1 - 0.33 10.5 16.6 0.41 10.2 11.5 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF2390 PF09523.5 EMD00291.1 - 0.64 10.2 6.3 0.95 9.6 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Rootletin PF15035.1 EMD00291.1 - 1.1 9.1 15.1 4 7.3 1.9 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HR1 PF02185.11 EMD00291.1 - 1.3 8.8 11.1 3.9 7.2 2.6 2.6 1 1 1 2 2 2 0 Hr1 repeat DUF4140 PF13600.1 EMD00291.1 - 1.6 9.2 12.8 4.2 7.8 0.3 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tup_N PF08581.5 EMD00291.1 - 1.9 8.6 9.9 2.2 8.5 4.5 2.4 1 1 1 2 2 2 0 Tup N-terminal Cob_adeno_trans PF01923.13 EMD00291.1 - 2.6 7.8 8.5 0.97 9.2 1.0 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase FUSC PF04632.7 EMD00291.1 - 6.4 5.0 5.7 6.2 5.1 4.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Zein-binding PF04576.10 EMD00291.1 - 7.4 6.7 14.2 2.2 8.4 4.6 2.4 1 1 1 2 2 2 0 Zein-binding DivIC PF04977.10 EMD00291.1 - 7.9 6.0 17.7 6.8 6.2 0.2 3.4 1 1 1 3 3 3 0 Septum formation initiator SGT1 PF07093.6 EMD00292.1 - 2.8e-135 452.0 25.8 7.6e-114 381.2 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein SRF-TF PF00319.13 EMD00292.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) STAS_2 PF13466.1 EMD00293.1 - 0.022 14.7 5.2 0.12 12.4 0.4 2.7 1 1 1 2 2 2 0 STAS domain LPAM_1 PF08139.7 EMD00293.1 - 0.037 14.2 1.3 0.037 14.2 0.9 3.0 3 0 0 3 3 3 0 Prokaryotic membrane lipoprotein lipid attachment site DUF3305 PF11749.3 EMD00293.1 - 0.052 13.4 0.1 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) Guanylin PF02058.10 EMD00293.1 - 0.12 12.4 0.7 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Guanylin precursor Actin PF00022.14 EMD00294.1 - 4.5e-122 407.2 0.0 5.1e-122 407.0 0.0 1.0 1 0 0 1 1 1 1 Actin MBOAT PF03062.14 EMD00295.1 - 5.7e-45 153.8 15.3 5.7e-45 153.8 10.6 2.3 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Prominin PF05478.6 EMD00295.1 - 0.97 6.8 2.0 1.3 6.4 1.4 1.1 1 0 0 1 1 1 0 Prominin F-box-like_2 PF13013.1 EMD00296.1 - 0.047 13.4 0.2 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 EMD00296.1 - 0.049 13.3 0.3 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like NeA_P2 PF12312.3 EMD00296.1 - 0.079 12.1 4.1 0.21 10.7 2.8 1.7 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Daxx PF03344.10 EMD00296.1 - 6.8 5.0 14.4 13 4.1 10.0 1.3 1 0 0 1 1 1 0 Daxx Family MliC PF09864.4 EMD00297.1 - 0.07 12.8 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme PIP5K PF01504.13 EMD00298.1 - 3.2e-82 275.4 0.0 5e-82 274.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FtsZ_C PF12327.3 EMD00298.1 - 0.23 11.5 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Linker_histone PF00538.14 EMD00299.1 - 7e-21 74.1 0.2 1.3e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Aa_trans PF01490.13 EMD00301.1 - 2e-59 201.1 21.5 2.3e-59 200.9 14.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CLP_protease PF00574.18 EMD00302.1 - 4.2e-74 248.1 0.0 5.4e-74 247.7 0.0 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.11 EMD00302.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase ECH PF00378.15 EMD00302.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family Methyltransf_31 PF13847.1 EMD00305.1 - 2.8e-07 30.2 0.0 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD00305.1 - 0.0019 18.6 0.0 0.0025 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD00305.1 - 0.0034 17.8 0.0 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD00305.1 - 0.023 14.7 0.1 0.04 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMD00305.1 - 0.096 13.0 0.1 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMD00305.1 - 0.12 12.9 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_43 PF04616.9 EMD00306.1 - 3.9e-24 85.2 0.0 6.6e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 F-box-like PF12937.2 EMD00307.1 - 0.0022 17.6 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD00307.1 - 0.0046 16.5 0.1 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EMD00307.1 - 0.057 13.1 0.2 0.13 12.0 0.1 1.7 1 1 0 1 1 1 0 F-box-like domain PhyH PF05721.8 EMD00309.1 - 0.016 15.2 0.1 0.038 14.0 0.0 1.7 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) MAPEG PF01124.13 EMD00310.1 - 3.9e-09 36.2 2.3 3.9e-09 36.2 1.6 1.5 2 0 0 2 2 2 1 MAPEG family Glyco_hydro_32N PF00251.15 EMD00311.1 - 2.9e-45 154.9 2.3 4.6e-45 154.2 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EMD00311.1 - 4.4e-16 59.0 0.0 9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EMD00311.1 - 0.0039 16.7 0.4 0.021 14.5 0.3 2.4 1 0 0 1 1 1 1 BNR/Asp-box repeat EPSP_synthase PF00275.15 EMD00311.1 - 0.019 13.4 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Glt_symporter PF03616.9 EMD00311.1 - 0.41 9.0 1.8 0.61 8.5 1.3 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Sporozoite_P67 PF05642.6 EMD00311.1 - 7.7 4.2 13.3 13 3.5 9.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med9 PF07544.8 EMD00312.1 - 3.2e-15 55.6 0.8 4.9e-15 55.0 0.6 1.4 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 EMD00312.1 - 0.017 15.1 2.0 0.018 15.0 1.4 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex IncA PF04156.9 EMD00312.1 - 0.11 12.0 1.0 0.13 11.8 0.7 1.1 1 0 0 1 1 1 0 IncA protein Pox_A_type_inc PF04508.7 EMD00312.1 - 7.6 6.5 7.8 2.7 8.0 3.2 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Metalloenzyme PF01676.13 EMD00313.1 - 2.1e-73 246.8 0.1 2.4e-73 246.6 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EMD00313.1 - 3.1e-71 239.2 0.0 5.1e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EMD00313.1 - 8.5e-07 28.6 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMD00313.1 - 0.00023 20.4 0.0 0.00048 19.4 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 EMD00313.1 - 0.0021 16.8 0.0 0.053 12.2 0.0 2.1 2 0 0 2 2 2 1 Alkaline phosphatase AP_endonuc_2 PF01261.19 EMD00313.1 - 0.0031 16.8 0.0 0.0068 15.7 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Rho_N PF07498.7 EMD00313.1 - 0.004 16.8 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain SHMT PF00464.14 EMD00314.1 - 6.3e-198 657.0 0.0 7.4e-198 656.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EMD00314.1 - 5.9e-06 25.4 0.0 2.2e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMD00314.1 - 3.9e-05 22.5 0.0 5.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Sec7 PF01369.15 EMD00315.1 - 1e-37 129.6 0.0 1.9e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EMD00315.1 - 2.8e-16 59.7 0.0 6e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain LETM1 PF07766.8 EMD00316.1 - 1.1e-14 54.0 0.0 9e-12 44.5 0.0 2.1 1 1 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EMD00316.1 - 0.021 14.2 0.1 0.053 13.0 0.1 1.7 1 0 0 1 1 1 0 SAP domain P53_TAD PF08563.6 EMD00316.1 - 0.058 12.4 4.2 0.15 11.1 0.1 2.5 2 0 0 2 2 2 0 P53 transactivation motif RNA_polI_A34 PF08208.6 EMD00317.1 - 2.9e-27 95.6 0.0 2.9e-27 95.6 0.0 5.1 3 1 2 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 MobB PF03205.9 EMD00318.1 - 2.4e-08 33.7 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 EMD00318.1 - 8e-08 32.2 0.0 4.8e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 FtsK_SpoIIIE PF01580.13 EMD00318.1 - 0.0053 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Metallopep PF12044.3 EMD00319.1 - 3.9e-174 579.0 0.0 4.6e-174 578.8 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Astacin PF01400.19 EMD00319.1 - 0.04 13.2 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Whi5 PF08528.6 EMD00320.1 - 1.3e-07 31.0 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Aminotran_1_2 PF00155.16 EMD00322.1 - 1.4e-36 126.2 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Clathrin PF00637.15 EMD00323.1 - 1.4e-16 60.3 0.2 4.4e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EMD00323.1 - 8.7e-07 28.5 0.8 0.1 12.5 0.2 4.4 3 1 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EMD00323.1 - 0.00012 21.8 0.8 0.0003 20.5 0.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMD00323.1 - 0.032 13.9 0.2 0.066 12.9 0.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.1 EMD00323.1 - 0.033 13.9 0.4 0.068 12.9 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Vps39_1 PF10366.4 EMD00323.1 - 0.14 12.1 0.1 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.1 EMD00323.1 - 0.23 11.3 2.7 2.2 8.2 0.3 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EMD00323.1 - 3.2 7.8 3.5 0.9 9.6 0.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF155 PF02582.9 EMD00324.1 - 2.2e-46 157.9 0.0 3e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.7 EMD00324.1 - 5.4e-05 22.5 0.1 0.00011 21.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EMD00324.1 - 0.021 14.2 0.1 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Cupin MT0933_antitox PF14013.1 EMD00325.1 - 0.056 13.5 5.9 1.4 9.0 0.2 2.1 1 1 1 2 2 2 0 MT0933-like antitoxin protein Ykof PF07615.6 EMD00325.1 - 0.07 13.2 0.0 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 YKOF-related Family PP28 PF10252.4 EMD00327.1 - 7e-27 93.2 21.9 7e-27 93.2 15.2 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Frag1 PF10277.4 EMD00328.1 - 1.9e-41 141.9 15.8 2.3e-41 141.6 5.4 2.6 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family UPRTase PF14681.1 EMD00330.1 - 1.2e-27 96.4 0.3 3.7e-27 94.8 0.1 1.8 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_33 PF13671.1 EMD00330.1 - 0.00084 19.2 0.1 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EMD00330.1 - 0.0016 17.4 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain cobW PF02492.14 EMD00330.1 - 0.0016 17.8 0.0 0.0043 16.5 0.0 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EMD00330.1 - 0.0021 17.2 0.5 0.0085 15.2 0.0 2.1 3 0 0 3 3 3 1 Zeta toxin Vps23_core PF09454.5 EMD00330.1 - 0.0023 17.4 0.0 0.68 9.5 0.0 2.8 2 0 0 2 2 2 1 Vps23 core domain ABC_tran PF00005.22 EMD00330.1 - 0.0039 17.4 0.1 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 EMD00330.1 - 0.0047 15.8 0.0 0.0088 14.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ArgK PF03308.11 EMD00330.1 - 0.0048 15.7 0.0 0.0097 14.7 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 EMD00330.1 - 0.005 16.4 1.1 1.7 8.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMD00330.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMD00330.1 - 0.016 15.2 0.1 0.037 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 EMD00330.1 - 0.019 15.1 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EMD00330.1 - 0.02 14.8 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMD00330.1 - 0.042 14.1 0.2 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMD00330.1 - 0.043 13.7 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EMD00330.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMD00330.1 - 0.065 14.0 0.7 0.18 12.6 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMD00330.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain PRTase_2 PF15609.1 EMD00330.1 - 0.084 12.1 0.1 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase Viral_helicase1 PF01443.13 EMD00330.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase HAD PF12710.2 EMD00330.1 - 0.13 12.3 0.2 0.31 11.1 0.0 1.9 2 0 0 2 2 1 0 haloacid dehalogenase-like hydrolase Cullin PF00888.17 EMD00331.1 - 3.8e-33 114.9 0.0 6.3e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Cullin family Sugar_tr PF00083.19 EMD00332.1 - 1.5e-92 310.5 27.4 1.9e-92 310.2 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD00332.1 - 3.4e-25 88.4 33.4 3.4e-25 88.4 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cys_Met_Meta_PP PF01053.15 EMD00334.1 - 5.9e-31 107.1 0.0 7.8e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMD00334.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Nrap PF03813.9 EMD00335.1 - 0 1054.7 0.0 0 1054.5 0.0 1.0 1 0 0 1 1 1 1 Nrap protein PCMT PF01135.14 EMD00336.1 - 1.4e-68 230.6 0.0 1.6e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EMD00336.1 - 2.6e-09 37.6 0.0 4.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD00336.1 - 8.3e-09 35.2 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD00336.1 - 2.6e-05 24.0 0.0 3.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD00336.1 - 0.00018 20.7 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EMD00336.1 - 0.00028 20.5 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EMD00336.1 - 0.00048 19.7 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MetW PF07021.7 EMD00336.1 - 0.0015 17.9 0.1 0.0034 16.7 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.7 EMD00336.1 - 0.0017 18.8 0.0 0.0046 17.4 0.0 1.8 1 1 1 2 2 1 1 Methyltransferase domain RrnaAD PF00398.15 EMD00336.1 - 0.0029 16.6 0.0 0.004 16.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMD00336.1 - 0.003 17.5 0.0 0.0065 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD00336.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EMD00336.1 - 0.025 14.9 0.0 0.054 13.8 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain FtsJ PF01728.14 EMD00336.1 - 0.027 14.4 0.0 0.096 12.6 0.0 1.6 1 1 0 2 2 2 0 FtsJ-like methyltransferase Fibrillarin PF01269.12 EMD00336.1 - 0.047 12.5 0.2 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Fibrillarin Methyltransf_4 PF02390.12 EMD00336.1 - 0.055 12.5 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_3 PF01596.12 EMD00336.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_24 PF13578.1 EMD00336.1 - 0.11 13.2 0.0 0.64 10.8 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMD00336.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EMD00336.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1180 PF06679.7 EMD00337.1 - 0.096 12.5 0.3 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AA_permease_2 PF13520.1 EMD00338.1 - 8.1e-33 113.5 39.2 2.5e-32 111.9 27.2 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD00338.1 - 7.2e-06 24.6 38.7 4.8e-05 21.8 26.8 2.2 1 1 0 1 1 1 1 Amino acid permease PrgI PF12666.2 EMD00338.1 - 1.1 9.4 0.0 1.1 9.4 0.0 4.6 6 0 0 6 6 6 0 PrgI family protein Glyco_hydro_17 PF00332.13 EMD00339.1 - 1.5e-05 24.2 6.9 4.9e-05 22.5 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Titin_Z PF09042.6 EMD00339.1 - 0.025 14.1 0.4 0.05 13.2 0.3 1.4 1 0 0 1 1 1 0 Titin Z zf-C2H2_4 PF13894.1 EMD00340.1 - 1.9e-08 34.0 15.2 0.012 15.9 1.9 3.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD00340.1 - 0.017 15.4 16.8 0.02 15.1 0.1 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF3431 PF11913.3 EMD00341.1 - 6.8e-24 84.5 0.0 8.1e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SprT-like PF10263.4 EMD00342.1 - 1e-46 158.4 2.6 1.4e-46 157.9 1.8 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EMD00342.1 - 0.031 14.3 0.5 0.26 11.3 0.1 2.5 3 0 0 3 3 3 0 Peptidase MA superfamily Zn-ribbon_8 PF09723.5 EMD00342.1 - 0.041 13.8 0.5 0.085 12.8 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Mog1 PF04603.7 EMD00343.1 - 9.5e-23 80.6 0.0 1.2e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein PCI PF01399.22 EMD00344.1 - 1.4e-10 41.4 0.1 3.2e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 PCI domain DUF2410 PF10307.4 EMD00345.1 - 1.2e-69 233.7 0.0 1.6e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) API5 PF05918.6 EMD00345.1 - 0.95 7.8 0.0 0.95 7.8 0.0 2.7 2 1 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) TPR_11 PF13414.1 EMD00347.1 - 1.1e-46 156.3 42.0 1e-07 31.4 0.1 13.6 11 3 3 15 15 15 9 TPR repeat TPR_1 PF00515.23 EMD00347.1 - 5.9e-32 107.9 19.7 4.2e-05 22.9 0.0 13.7 15 0 0 15 15 12 7 Tetratricopeptide repeat TPR_14 PF13428.1 EMD00347.1 - 9.1e-30 100.4 54.3 0.00015 22.1 0.3 17.4 15 3 4 19 19 15 8 Tetratricopeptide repeat TPR_2 PF07719.12 EMD00347.1 - 3.3e-29 98.4 48.2 0.0022 17.7 0.0 16.9 18 0 0 18 18 16 9 Tetratricopeptide repeat TPR_17 PF13431.1 EMD00347.1 - 4e-27 92.1 18.4 0.004 17.2 0.1 14.9 17 0 0 17 17 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMD00347.1 - 1.4e-26 92.5 42.4 7.6e-08 32.5 0.7 12.9 12 3 2 14 14 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 EMD00347.1 - 1.4e-25 89.3 74.0 3e-05 24.5 2.0 15.9 11 6 3 17 17 16 8 Tetratricopeptide repeat TPR_12 PF13424.1 EMD00347.1 - 8.9e-21 73.6 39.7 0.00077 19.3 0.0 12.9 7 5 7 14 14 14 8 Tetratricopeptide repeat TPR_8 PF13181.1 EMD00347.1 - 2.8e-20 70.5 11.4 0.032 14.0 0.0 11.7 10 2 2 12 12 11 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMD00347.1 - 4e-18 63.7 21.6 0.017 14.8 0.0 13.1 12 0 0 12 12 12 4 Tetratricopeptide repeat Apc3 PF12895.2 EMD00347.1 - 1e-10 41.6 25.8 0.005 16.9 0.0 9.4 8 4 1 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EMD00347.1 - 3.8e-10 39.7 20.2 0.44 10.6 0.1 10.4 9 2 1 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 EMD00347.1 - 5.2e-10 39.1 28.4 0.095 13.1 0.0 13.7 17 0 0 17 17 15 2 Tetratricopeptide repeat Coatomer_E PF04733.9 EMD00347.1 - 5.5e-05 22.5 1.8 0.011 14.9 0.1 3.4 4 0 0 4 4 4 1 Coatomer epsilon subunit TPR_9 PF13371.1 EMD00347.1 - 6e-05 22.8 39.3 0.0049 16.6 1.5 11.0 10 2 1 11 11 11 1 Tetratricopeptide repeat TPR_3 PF07720.7 EMD00347.1 - 0.12 12.2 5.3 1.5 8.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EMD00347.1 - 1 8.0 8.6 27 3.3 0.0 5.0 6 1 0 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 EMD00347.1 - 2.9 8.5 37.2 0.38 11.3 0.1 10.6 10 0 0 10 10 9 0 Tetratricopeptide repeat TerB PF05099.8 EMD00347.1 - 4.4 7.0 20.4 0.077 12.7 0.4 4.9 6 0 0 6 6 6 0 Tellurite resistance protein TerB RCC1 PF00415.13 EMD00348.1 - 2.1e-33 114.2 0.2 5e-08 33.0 0.0 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMD00348.1 - 1.1e-15 56.7 27.6 4.7e-13 48.3 0.2 6.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat DUF1663 PF07909.6 EMD00348.1 - 0.0098 14.4 0.1 0.018 13.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1663) RRM_1 PF00076.17 EMD00352.1 - 3.3e-19 68.2 0.2 6.7e-19 67.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD00352.1 - 2.1e-13 50.0 0.0 5.1e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD00352.1 - 8.2e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMD00352.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCHC PF00098.18 EMD00353.1 - 8.3e-12 44.4 9.7 1.1e-05 25.0 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EMD00353.1 - 3e-09 36.3 0.1 5e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EMD00353.1 - 3e-07 30.0 4.9 0.00037 20.1 1.4 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EMD00353.1 - 3e-06 26.7 0.1 7.7e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EMD00353.1 - 0.00028 20.4 9.0 0.03 13.9 0.3 3.0 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 EMD00353.1 - 0.0007 19.2 6.0 0.3 10.7 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EMD00353.1 - 0.03 13.8 0.2 0.03 13.8 0.1 3.3 2 1 1 3 3 3 0 Zinc knuckle zf-HIT PF04438.11 EMD00353.1 - 2 8.1 3.8 4.8 6.9 0.4 2.2 2 0 0 2 2 2 0 HIT zinc finger Grp1_Fun34_YaaH PF01184.14 EMD00354.1 - 2.2e-28 99.0 27.0 2.8e-28 98.6 18.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family UQ_con PF00179.21 EMD00355.1 - 1.2e-37 128.5 0.0 1.3e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMD00355.1 - 0.028 14.2 0.1 0.067 13.0 0.1 1.8 1 1 0 1 1 1 0 RWD domain Cupin_8 PF13621.1 EMD00357.1 - 3.5e-39 134.8 0.0 4.5e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMD00357.1 - 2.8e-06 26.8 0.0 0.00028 20.2 0.0 2.4 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.17 EMD00357.1 - 0.0012 19.0 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Pkinase PF00069.20 EMD00358.1 - 3.5e-19 68.9 0.0 1.1e-17 64.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD00358.1 - 1.4e-09 37.4 0.0 3.5e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD00358.1 - 0.053 12.4 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MFS_1 PF07690.11 EMD00360.1 - 1e-32 113.2 30.0 1.2e-32 113.0 20.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MatE PF01554.13 EMD00361.1 - 0.00014 21.4 1.9 0.00014 21.4 1.3 2.4 2 0 0 2 2 2 1 MatE Polysacc_synt_C PF14667.1 EMD00361.1 - 0.00079 19.2 0.2 0.00079 19.2 0.2 2.3 3 0 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DEAD PF00270.24 EMD00362.1 - 3e-43 147.2 0.1 5e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD00362.1 - 3.5e-21 74.8 0.0 9e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD00362.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit adh_short PF00106.20 EMD00363.1 - 3.4e-26 92.1 0.7 6.8e-26 91.1 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD00363.1 - 1.7e-07 31.2 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD00363.1 - 2.5e-07 30.5 2.0 7.4e-07 29.0 1.4 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD00363.1 - 0.044 13.1 0.1 0.095 12.1 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peroxidase_2 PF01328.12 EMD00365.1 - 2.5e-15 55.9 0.1 6e-15 54.7 0.1 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 Ribosomal_L7Ae PF01248.21 EMD00366.1 - 1.3e-27 95.1 1.2 1.5e-27 94.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Vac_ImportDeg PF09783.4 EMD00367.1 - 2.3e-28 98.8 0.0 1.2e-25 90.0 0.0 2.8 2 1 0 2 2 2 1 Vacuolar import and degradation protein DUF716 PF04819.7 EMD00373.1 - 0.0094 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF716) TPP_enzyme_N PF02776.13 EMD00375.1 - 6.3e-36 123.4 0.2 1.5e-35 122.1 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMD00375.1 - 3.4e-23 81.9 0.0 1e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMD00375.1 - 1e-14 54.4 2.9 2.3e-12 46.7 0.1 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GST_N_3 PF13417.1 EMD00376.1 - 2.1e-13 50.2 0.0 3.7e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD00376.1 - 3.6e-12 46.2 0.0 3.5e-11 43.1 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD00376.1 - 2.7e-11 43.3 0.0 4.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMD00376.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMD00376.1 - 6.5e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD00376.1 - 8e-08 32.6 0.0 1.7e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_trans_1_2 PF13524.1 EMD00376.1 - 0.044 14.0 0.1 6.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 ERp29 PF07749.7 EMD00376.1 - 0.086 13.4 0.2 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain SKG6 PF08693.5 EMD00377.1 - 0.0096 15.2 3.1 0.0096 15.2 2.1 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain MLANA PF14991.1 EMD00377.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A DUF4349 PF14257.1 EMD00377.1 - 0.11 11.7 0.8 0.17 11.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3535 PF12054.3 EMD00379.1 - 5.5e-135 450.4 1.3 2.5e-134 448.2 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EMD00379.1 - 2.7e-72 243.0 0.0 5.6e-72 242.0 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.17 EMD00379.1 - 2.3e-16 58.3 17.4 0.0047 16.8 0.0 11.5 12 0 0 12 12 12 4 HEAT repeat Helicase_C PF00271.26 EMD00379.1 - 1.1e-13 50.8 0.0 3.1e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EMD00379.1 - 1.2e-06 28.7 0.1 0.044 14.1 0.0 3.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EMD00379.1 - 1.2e-05 25.4 26.8 0.0051 17.0 0.0 9.0 8 2 1 9 9 9 2 HEAT repeats CLASP_N PF12348.3 EMD00379.1 - 7.1e-05 22.2 0.1 0.79 9.0 0.0 3.6 2 2 1 3 3 3 2 CLASP N terminal Cnd1 PF12717.2 EMD00379.1 - 0.018 14.9 0.3 3.4 7.4 0.0 3.9 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 EMD00379.1 - 0.024 14.7 1.4 53 4.0 0.0 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EMD00379.1 - 3.4 8.2 32.7 0.79 10.3 0.0 10.4 12 0 0 12 12 12 0 HEAT-like repeat AMP-binding PF00501.23 EMD00380.1 - 1.2e-68 231.5 0.1 1.5e-68 231.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD00380.1 - 1e-16 61.6 0.0 2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EMD00381.1 - 7.7e-25 85.8 17.4 4.1e-09 35.9 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EMD00381.1 - 0.00076 19.2 0.2 1.4 8.6 0.0 3.3 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EMD00381.1 - 0.015 14.4 0.2 0.91 8.5 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Apc4_WD40 PF12894.2 EMD00381.1 - 0.018 14.5 0.0 0.071 12.6 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.7 EMD00381.1 - 0.018 14.3 0.0 0.12 11.7 0.0 2.1 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region BAG PF02179.11 EMD00382.1 - 7.5e-17 61.2 0.3 1.3e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EMD00382.1 - 0.00075 18.8 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Nop53 PF07767.6 EMD00382.1 - 0.093 11.7 4.5 0.17 10.8 3.1 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sporozoite_P67 PF05642.6 EMD00382.1 - 0.31 8.8 4.0 0.43 8.3 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2407 PF10302.4 EMD00382.1 - 0.54 10.4 4.0 3.4 7.9 2.8 2.1 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Spt5_N PF11942.3 EMD00382.1 - 1.2 9.7 13.2 0.26 11.9 6.2 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SIR2 PF02146.12 EMD00383.1 - 2e-26 92.7 0.0 1.3e-25 90.1 0.0 2.1 1 1 0 1 1 1 1 Sir2 family DUF4456 PF14644.1 EMD00383.1 - 0.045 12.9 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Paired_CXXCH_1 PF09699.5 EMD00383.1 - 0.048 13.1 1.1 0.11 12.0 0.8 1.6 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) Med16 PF11635.3 EMD00384.1 - 7.8e-86 288.6 0.0 1.1e-85 288.2 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 PEX11 PF05648.9 EMD00384.1 - 0.028 13.6 0.2 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Lectin_N PF03954.9 EMD00386.1 - 0.094 12.1 0.5 0.37 10.2 0.1 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CsbD PF05532.7 EMD00388.1 - 0.00043 19.9 7.5 0.0053 16.3 1.7 2.4 2 0 0 2 2 2 2 CsbD-like 2Fe-2S_thioredx PF01257.14 EMD00390.1 - 0.26 10.8 0.0 0.48 9.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Peptidase_S8 PF00082.17 EMD00392.1 - 8.6e-31 107.1 0.0 3.4e-30 105.1 0.0 1.9 1 1 0 1 1 1 1 Subtilase family Iso_dh PF00180.15 EMD00393.1 - 1.1e-82 277.7 0.0 1.4e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Plasmid_stab_B PF10784.4 EMD00393.1 - 0.089 12.4 0.1 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Plasmid stability protein DIT1_PvcA PF05141.7 EMD00395.1 - 4.3e-70 236.1 0.0 5.5e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 EMD00395.1 - 2.8e-32 112.4 0.1 3.9e-32 111.9 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1043 PF06295.7 EMD00395.1 - 0.12 12.0 0.0 6.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) PP2C PF00481.16 EMD00396.1 - 7.3e-22 77.9 0.0 4.4e-20 72.1 0.0 2.2 1 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EMD00396.1 - 0.0073 16.0 0.1 0.49 10.0 0.0 2.9 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Methyltransf_23 PF13489.1 EMD00397.1 - 1.2e-11 44.5 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD00397.1 - 5.6e-10 39.5 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD00397.1 - 1.9e-09 37.8 0.0 4.7e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD00397.1 - 1.5e-06 27.9 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD00397.1 - 0.0089 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF2622 PF11080.3 EMD00397.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2622) GST_N_3 PF13417.1 EMD00398.1 - 8.8e-11 41.8 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD00398.1 - 0.00034 20.5 0.0 0.00075 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMD00399.1 - 5.7e-11 42.7 0.0 9.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD00399.1 - 2.4e-08 33.8 0.1 4e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMD00399.1 - 0.00084 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Amidohydro_4 PF13147.1 EMD00400.1 - 1.3e-08 35.2 0.1 2.3e-08 34.4 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMD00400.1 - 5.3e-05 22.9 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Pribosyl_synth PF14572.1 EMD00402.1 - 1.7e-36 125.7 0.9 3.4e-33 114.9 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EMD00402.1 - 6.4e-35 119.3 0.0 1.9e-34 117.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EMD00402.1 - 1.7e-10 40.7 0.1 3.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMD00402.1 - 0.0088 15.2 0.1 0.015 14.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_tran_WecB PF03808.8 EMD00402.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Ras PF00071.17 EMD00403.1 - 1.2e-18 67.0 0.0 2.5e-18 65.9 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMD00403.1 - 1.3e-07 32.1 0.0 3.8e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein NACHT PF05729.7 EMD00403.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EMD00403.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 EMD00403.1 - 0.13 11.5 0.0 0.71 9.0 0.0 2.1 3 0 0 3 3 3 0 ADP-ribosylation factor family Bestrophin PF01062.16 EMD00405.1 - 3.7e-49 167.2 1.0 1.4e-47 162.0 0.7 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FAD_binding_3 PF01494.14 EMD00406.1 - 5.1e-18 65.2 0.1 1.1e-17 64.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD00406.1 - 2.3e-11 43.2 2.4 7.7e-05 21.7 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD00406.1 - 9.5e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMD00406.1 - 2.7e-06 26.1 0.0 0.023 13.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EMD00406.1 - 3.4e-06 26.1 0.1 6.4e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD00406.1 - 0.00028 20.8 0.1 0.0026 17.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD00406.1 - 0.00035 20.9 0.1 0.036 14.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD00406.1 - 0.00059 19.0 0.0 0.00094 18.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMD00406.1 - 0.0023 16.6 1.4 0.04 12.5 0.1 2.4 2 1 0 3 3 3 1 Tryptophan halogenase SE PF08491.5 EMD00406.1 - 0.0038 16.1 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 EMD00406.1 - 0.0046 15.9 1.6 1.8 7.3 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein Thi4 PF01946.12 EMD00406.1 - 0.0062 15.6 0.1 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EMD00406.1 - 0.0073 16.3 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD00406.1 - 0.019 13.8 0.1 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EMD00406.1 - 0.023 14.3 0.3 0.093 12.3 0.0 2.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMD00406.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 EMD00406.1 - 0.21 11.3 2.1 3.7 7.2 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EMD00407.1 - 5.1e-29 101.0 47.4 3e-25 88.6 16.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EMD00408.1 - 2.3e-17 62.7 54.7 1.1e-12 47.3 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rrn6 PF10214.4 EMD00409.1 - 1.8e-85 287.6 6.4 3.6e-67 227.1 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor FAD_binding_3 PF01494.14 EMD00410.1 - 4.3e-17 62.2 0.3 9.6e-17 61.0 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD00410.1 - 1.9e-05 23.7 0.0 0.056 12.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD00410.1 - 5.8e-05 23.4 0.7 0.051 13.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD00410.1 - 0.011 15.5 0.6 0.096 12.4 0.1 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD00410.1 - 0.027 14.3 0.7 0.23 11.2 0.5 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD00410.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_trans_2_3 PF13632.1 EMD00411.1 - 4.3e-47 160.3 3.1 4.3e-47 160.3 2.1 2.3 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD00411.1 - 2.9e-10 40.3 0.2 7.5e-09 35.7 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMD00411.1 - 1.7e-06 27.8 0.0 5.5e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMD00411.1 - 0.00021 20.5 0.7 0.0014 17.9 0.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 21 Lactamase_B PF00753.22 EMD00412.1 - 1.2e-17 64.2 0.3 1.6e-17 63.8 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD00412.1 - 8.9e-05 22.1 0.9 0.00018 21.0 0.6 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF677 PF05055.7 EMD00414.1 - 0.26 9.9 0.3 0.43 9.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) MFS_1 PF07690.11 EMD00415.1 - 1.5e-06 27.1 32.6 4e-06 25.7 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EMD00417.1 - 2.7e-08 33.4 0.0 8.5e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD00417.1 - 3e-06 26.9 0.0 2.2e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMD00417.1 - 0.0034 18.2 0.0 0.022 15.6 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Fer4_18 PF13746.1 EMD00418.1 - 0.064 13.6 0.1 0.075 13.4 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain Glyoxalase_3 PF13468.1 EMD00419.1 - 1.7e-07 31.2 0.0 1.3e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain DnaJ PF00226.26 EMD00420.1 - 8.5e-17 60.6 0.4 2.4e-16 59.2 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain FAA_hydrolase PF01557.13 EMD00421.1 - 1.6e-58 197.7 0.0 2.3e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SET PF00856.23 EMD00423.1 - 0.11 12.8 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 SET domain Yippee-Mis18 PF03226.9 EMD00424.1 - 4.7e-23 81.0 2.2 5.3e-23 80.8 1.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EMD00424.1 - 0.012 15.5 0.4 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease DUF2039 PF10217.4 EMD00424.1 - 0.04 13.9 0.6 0.04 13.9 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 EMD00424.1 - 0.27 11.1 2.1 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Arc_trans_TRASH PF08394.5 EMD00424.1 - 0.63 10.2 5.5 3.8 7.7 0.3 2.4 2 0 0 2 2 2 0 Archaeal TRASH domain Endonuclease_7 PF02945.10 EMD00424.1 - 2.3 7.9 6.3 3.2 7.5 3.7 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII PGPGW PF09656.5 EMD00427.1 - 0.11 11.8 0.7 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Peptidase_M20 PF01546.23 EMD00428.1 - 2.8e-07 30.2 0.1 4e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMD00428.1 - 0.00014 21.5 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ketoacyl-synt PF00109.21 EMD00429.1 - 2.3e-75 253.3 0.2 5.3e-75 252.1 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD00429.1 - 6e-44 150.6 0.1 1.1e-43 149.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMD00429.1 - 4.9e-33 113.4 0.2 1.2e-32 112.2 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EMD00429.1 - 2.1e-26 93.5 0.0 1.1e-25 91.1 0.0 2.2 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EMD00429.1 - 5.9e-22 77.7 5.7 2.1e-10 40.6 0.3 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EMD00429.1 - 9.4e-08 31.9 0.4 0.021 14.6 0.1 3.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD00429.1 - 5.7e-07 29.6 4.5 0.0047 16.8 0.0 3.9 3 1 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EMD00429.1 - 0.0009 18.2 0.1 0.0021 17.1 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lipase_3 PF01764.20 EMD00429.1 - 0.024 14.2 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 0 Lipase (class 3) Acyl_transf_1 PF00698.16 EMD00431.1 - 7.7e-54 183.1 1.1 2.6e-50 171.5 0.0 4.0 3 1 0 3 3 3 2 Acyl transferase domain DUF1729 PF08354.5 EMD00431.1 - 9.3e-27 92.5 0.0 2e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EMD00431.1 - 1.7e-26 91.9 0.1 4.6e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EMD00431.1 - 5.4e-08 32.6 0.0 1.6e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EMD00431.1 - 3.1e-05 23.2 0.1 0.0001 21.5 0.1 1.9 1 0 0 1 1 1 1 Nitronate monooxygenase ketoacyl-synt PF00109.21 EMD00432.1 - 2.1e-19 69.9 0.9 1.3e-18 67.4 0.3 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EMD00432.1 - 1.7e-15 57.4 0.0 4.2e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EMD00432.1 - 2.6e-14 53.0 0.0 5.7e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EMD00432.1 - 6e-12 45.4 0.0 2.4e-11 43.5 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EMD00432.1 - 5.6e-07 29.6 0.0 2.1e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD00432.1 - 0.00025 20.7 0.0 0.0011 18.6 0.0 2.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EMD00432.1 - 0.0021 17.9 0.1 0.0049 16.7 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 EMD00432.1 - 0.0061 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMD00432.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMD00432.1 - 0.024 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EMD00433.1 - 1.4e-37 129.2 54.8 1.4e-37 129.2 38.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD00433.1 - 2.2e-05 23.2 15.8 2.2e-05 23.2 11.0 3.7 2 2 1 3 3 3 2 Sugar (and other) transporter DUF3169 PF11368.3 EMD00433.1 - 0.081 12.1 3.1 0.16 11.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) WTF PF03303.8 EMD00433.1 - 5 6.4 5.5 13 5.1 3.8 1.6 1 1 0 1 1 1 0 WTF protein Abhydrolase_5 PF12695.2 EMD00434.1 - 1.3e-13 50.9 0.1 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD00434.1 - 2e-10 40.9 1.9 2e-10 40.9 1.3 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EMD00434.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EMD00434.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Cutinase Zn_clus PF00172.13 EMD00435.1 - 7.9e-09 35.2 9.8 1.5e-08 34.4 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.13 EMD00436.1 - 2.5e-17 62.9 0.0 3.3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase FSH1 PF03959.8 EMD00437.1 - 5.9e-23 81.4 0.0 1.1e-21 77.2 0.0 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ADH_zinc_N_2 PF13602.1 EMD00438.1 - 9e-21 75.0 0.0 1.6e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMD00438.1 - 2.7e-14 52.8 0.0 4.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.3 EMD00440.1 - 3.2e-06 25.9 0.5 3.2e-06 25.9 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1793 PF08760.6 EMD00441.1 - 5.6e-71 237.8 0.3 1.5e-70 236.4 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Ndufs5 PF10200.4 EMD00442.1 - 0.00047 20.0 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EMD00442.1 - 0.00064 19.7 0.1 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 EMD00442.1 - 0.055 13.4 0.3 0.09 12.8 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Man-6-P_recep PF02157.10 EMD00443.1 - 6.4e-10 38.5 0.1 1.3e-09 37.4 0.1 1.4 2 0 0 2 2 2 1 Mannose-6-phosphate receptor CIMR PF00878.13 EMD00443.1 - 2.5e-06 27.3 0.0 0.0054 16.5 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PBP1_TM PF14812.1 EMD00443.1 - 0.0066 16.7 3.5 0.0066 16.7 2.4 1.9 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EMD00443.1 - 0.038 13.4 2.5 0.058 12.9 1.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EMD00443.1 - 0.13 12.4 8.5 0.21 11.7 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2361 PF10153.4 EMD00444.1 - 7.1e-33 113.1 1.6 1.9e-32 111.8 1.1 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Med9 PF07544.8 EMD00444.1 - 0.61 9.8 5.5 2.4 7.9 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 V-SNARE PF05008.10 EMD00444.1 - 0.66 10.1 3.6 16 5.7 0.2 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF3323 PF11796.3 EMD00444.1 - 1.5 8.0 10.4 0.16 11.3 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Cep57_CLD_2 PF14197.1 EMD00444.1 - 4.2 7.3 10.4 1.2 9.0 2.3 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Abhydrolase_5 PF12695.2 EMD00446.1 - 4.8e-07 29.6 0.0 9.4e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD00446.1 - 1.9e-06 27.9 0.2 5.7e-06 26.3 0.2 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMD00446.1 - 0.00013 21.6 0.0 0.00034 20.2 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EMD00446.1 - 0.0036 16.8 0.0 0.0096 15.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Apelin PF15360.1 EMD00446.1 - 0.014 15.6 0.1 0.078 13.1 0.1 2.3 1 0 0 1 1 1 0 APJ endogenous ligand Lipase_3 PF01764.20 EMD00446.1 - 0.035 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EMD00446.1 - 0.036 14.3 10.2 0.076 13.2 0.0 2.8 2 1 0 2 2 2 0 Thioesterase domain Borrelia_P83 PF05262.6 EMD00446.1 - 0.26 9.5 16.8 0.37 9.0 11.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pro_CA PF00484.14 EMD00447.1 - 5.3e-07 29.7 0.0 6.2e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase FAD_binding_8 PF08022.7 EMD00448.1 - 8.1e-18 64.2 0.0 1.8e-16 59.9 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMD00448.1 - 1.5e-16 60.6 0.0 1.6e-10 41.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMD00448.1 - 1.5e-15 57.3 16.1 1.5e-15 57.3 11.2 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMD00448.1 - 0.11 12.6 0.0 1.1 9.3 0.0 2.4 1 1 1 2 2 2 0 Oxidoreductase FAD-binding domain adh_short PF00106.20 EMD00450.1 - 2.1e-18 66.8 0.2 3.5e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD00450.1 - 3.5e-08 33.3 0.1 5.9e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMD00450.1 - 0.0077 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.13 EMD00451.1 - 0.014 15.2 1.2 0.014 15.2 0.8 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.9 EMD00452.1 - 3.3e-09 36.2 0.0 7.5e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Whi5 PF08528.6 EMD00453.1 - 6.6e-05 22.4 0.1 0.00012 21.5 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Acetyltransf_1 PF00583.19 EMD00454.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD00454.1 - 4e-05 23.6 0.0 7.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD00454.1 - 0.0014 18.7 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribonuclease_T2 PF00445.13 EMD00455.1 - 2e-44 151.4 0.5 2.8e-44 151.0 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Peptidase_C1 PF00112.18 EMD00455.1 - 0.012 15.5 3.9 0.045 13.6 0.1 2.3 2 0 0 2 2 2 0 Papain family cysteine protease Lip_prot_lig_C PF10437.4 EMD00456.1 - 0.065 12.9 0.0 0.068 12.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus TRAM_LAG1_CLN8 PF03798.11 EMD00457.1 - 4e-44 150.5 12.4 4e-44 150.5 8.6 1.4 2 0 0 2 2 2 1 TLC domain DUF4234 PF14018.1 EMD00457.1 - 0.0057 16.3 0.2 0.0057 16.3 0.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4234) adh_short PF00106.20 EMD00458.1 - 3.6e-15 56.2 0.1 5.1e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD00458.1 - 4e-08 33.1 0.1 6e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD00458.1 - 8.6e-05 22.0 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMD00458.1 - 0.00052 19.8 0.0 0.00069 19.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMD00458.1 - 0.08 12.9 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF61 PF01886.11 EMD00458.1 - 0.11 12.3 0.0 7.6 6.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF61 RmlD_sub_bind PF04321.12 EMD00458.1 - 0.16 10.8 0.0 6.7 5.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Nol1_Nop2_Fmu PF01189.12 EMD00459.1 - 1.2e-44 152.8 0.0 1e-21 77.5 0.0 3.4 2 1 1 3 3 3 3 NOL1/NOP2/sun family Metallophos PF00149.23 EMD00459.1 - 1.3e-10 40.9 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD00459.1 - 1.5e-10 41.1 0.0 3.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methyltransf_26 PF13659.1 EMD00459.1 - 0.0049 16.8 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EMD00459.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase FliD_N PF02465.13 EMD00460.1 - 0.074 13.4 0.5 0.18 12.2 0.3 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus vATP-synt_AC39 PF01992.11 EMD00461.1 - 3.1e-112 375.0 0.0 3.5e-112 374.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF423 PF04241.10 EMD00461.1 - 0.088 12.7 0.1 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF423) ubiquitin PF00240.18 EMD00463.1 - 9e-06 24.9 0.0 1.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EMD00463.1 - 0.035 14.6 0.0 0.056 14.0 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF4456 PF14644.1 EMD00467.1 - 0.2 10.8 0.5 0.38 9.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Mating_C PF12737.2 EMD00467.1 - 3.6 6.3 14.0 0.14 11.0 5.3 1.6 1 1 1 2 2 2 0 C-terminal domain of homeodomain 1 Fungal_trans PF04082.13 EMD00468.1 - 8.8e-28 96.8 0.0 1.5e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD00468.1 - 1.3e-08 34.5 11.7 2e-08 33.9 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1906 PF08924.6 EMD00468.1 - 0.058 13.2 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) MFS_1 PF07690.11 EMD00469.1 - 6.5e-35 120.4 51.3 1.1e-31 109.8 17.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD00469.1 - 3.3e-09 35.8 7.8 3.3e-09 35.8 5.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EMD00469.1 - 0.01 15.5 2.0 0.082 12.7 0.0 3.2 3 0 0 3 3 3 0 MFS_1 like family UQ_con PF00179.21 EMD00472.1 - 1.7e-11 43.7 0.1 2.7e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMD00472.1 - 0.058 13.2 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain FAD_binding_4 PF01565.18 EMD00474.1 - 2.2e-13 49.8 0.1 1.5e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.7 EMD00474.1 - 4.1e-07 29.7 0.5 1.5e-06 27.9 0.3 2.0 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EMD00474.1 - 0.005 16.0 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD-oxidase_C PF02913.14 EMD00474.1 - 0.028 13.7 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Acyl-CoA_dh_1 PF00441.19 EMD00475.1 - 3e-31 108.5 0.5 5.5e-31 107.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD00475.1 - 4.4e-21 75.5 0.2 9.4e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD00475.1 - 8.3e-17 61.6 0.1 1.5e-15 57.5 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD00475.1 - 2.9e-13 49.1 0.1 6.3e-13 48.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain tRNA-synt_2b PF00587.20 EMD00476.1 - 3.2e-19 69.1 0.0 4.6e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EMD00476.1 - 5e-09 36.1 0.9 8.4e-09 35.4 0.6 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Ribosomal_S2 PF00318.15 EMD00477.1 - 2.9e-43 147.5 0.1 2.3e-22 79.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EMD00478.1 - 2.9e-14 52.5 0.0 5.7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 CcoS PF03597.10 EMD00479.1 - 0.03 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Zn_clus PF00172.13 EMD00480.1 - 1.7e-07 31.0 9.0 4e-07 29.8 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD00480.1 - 2.8e-07 29.4 0.7 0.00046 18.8 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain APG17 PF04108.7 EMD00480.1 - 0.0099 14.7 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Oxidored_molyb PF00174.14 EMD00481.1 - 4.2e-47 159.7 0.0 1e-46 158.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EMD00481.1 - 2.9e-25 88.3 2.1 5.8e-25 87.4 1.4 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 EMD00481.1 - 0.033 14.0 0.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 SLBB domain PH PF00169.24 EMD00482.1 - 5.4e-10 39.3 0.1 2.2e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 EMD00482.1 - 0.00048 19.5 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EMD00482.1 - 0.19 11.9 1.6 3.1 8.1 1.1 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain NmrA PF05368.8 EMD00483.1 - 4.6e-23 81.6 0.0 6.7e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD00483.1 - 7e-15 55.5 0.1 1e-14 54.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMD00483.1 - 0.0012 17.9 0.1 0.0016 17.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMD00483.1 - 0.0074 15.7 0.1 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD00483.1 - 0.035 12.8 0.0 0.085 11.5 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family UAA PF08449.6 EMD00485.1 - 8.5e-76 254.7 9.1 3.7e-75 252.6 6.3 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMD00485.1 - 6.3e-08 32.7 19.7 0.00014 21.8 5.1 3.3 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EMD00485.1 - 6.7e-07 28.6 5.3 0.00054 19.1 0.4 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EMD00485.1 - 1.5e-06 28.4 11.9 0.0019 18.3 3.1 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EMD00485.1 - 0.0019 17.8 4.5 0.0019 17.8 3.1 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family zf-CCCH PF00642.19 EMD00486.1 - 0.79 9.4 17.2 0.035 13.7 2.7 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_S3_C PF00189.15 EMD00487.1 - 8.2e-16 58.0 0.0 1.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EMD00487.1 - 1.1e-09 37.6 0.0 2.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 KH domain Mito_carr PF00153.22 EMD00490.1 - 1.5e-65 216.9 5.0 3.4e-24 84.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.17 EMD00491.1 - 9.6e-13 47.6 0.1 2e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMD00491.1 - 0.0062 16.3 0.3 0.016 15.0 0.2 1.6 1 1 0 1 1 1 1 Bd3614-like deaminase RecR PF02132.10 EMD00491.1 - 0.035 13.5 0.1 3.8 7.0 0.1 2.5 2 0 0 2 2 2 0 RecR protein Cpn60_TCP1 PF00118.19 EMD00493.1 - 2.1e-156 521.3 1.6 2.3e-156 521.1 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Reo_sigmaC PF04582.7 EMD00494.1 - 0.094 11.8 0.5 0.14 11.3 0.3 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein ABC2_membrane PF01061.19 EMD00495.1 - 9.7e-90 299.3 53.0 4.3e-48 163.2 11.3 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EMD00495.1 - 4.4e-37 127.4 0.0 4.4e-18 65.9 0.0 2.9 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMD00495.1 - 1.6e-30 104.8 10.6 2.6e-27 94.4 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EMD00495.1 - 6.7e-08 32.5 0.1 1.8e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EMD00495.1 - 6e-06 25.5 0.0 0.00062 18.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMD00495.1 - 1.1e-05 24.9 0.2 0.027 13.8 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMD00495.1 - 6e-05 22.4 0.3 0.16 11.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 EMD00495.1 - 7.3e-05 22.6 0.0 0.08 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EMD00495.1 - 8.8e-05 22.6 0.0 0.43 10.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 EMD00495.1 - 0.00011 21.7 0.1 0.0026 17.2 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EMD00495.1 - 0.00013 21.8 0.1 0.2 11.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EMD00495.1 - 0.0016 18.4 0.0 0.007 16.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EMD00495.1 - 0.0016 18.5 0.1 0.62 10.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EMD00495.1 - 0.0018 17.8 0.1 0.99 8.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family UPF0079 PF02367.12 EMD00495.1 - 0.0026 17.3 0.4 0.12 11.9 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EMD00495.1 - 0.0027 17.9 0.0 0.089 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD00495.1 - 0.0039 18.0 0.0 0.16 12.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EMD00495.1 - 0.0053 16.7 3.5 0.059 13.3 0.4 3.3 3 1 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.14 EMD00495.1 - 0.019 14.1 0.9 0.14 11.3 0.0 2.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.17 EMD00495.1 - 0.023 13.5 0.4 3.1 6.5 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.7 EMD00495.1 - 0.034 13.8 0.1 0.8 9.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EMD00495.1 - 0.045 13.3 0.1 0.36 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMD00495.1 - 0.083 12.4 0.8 2.9 7.4 0.2 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EMD00495.1 - 0.089 12.2 0.2 0.43 10.0 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EMD00495.1 - 0.11 11.5 0.2 0.49 9.3 0.1 1.9 2 0 0 2 2 2 0 Septin AAA_15 PF13175.1 EMD00495.1 - 0.11 11.5 0.0 6.3 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain GBP PF02263.14 EMD00495.1 - 0.16 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Miro PF08477.8 EMD00495.1 - 0.18 12.3 0.5 6.3 7.3 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein AAA_10 PF12846.2 EMD00495.1 - 0.27 10.6 1.7 7.2 5.9 0.3 2.5 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 EMD00495.1 - 0.31 10.8 2.7 1.6 8.5 0.0 3.2 4 0 0 4 4 3 0 Dynamin family ABC2_membrane_3 PF12698.2 EMD00495.1 - 0.92 8.4 48.6 0.016 14.2 9.8 3.3 3 0 0 3 3 2 0 ABC-2 family transporter protein CHCH PF06747.8 EMD00496.1 - 0.4 10.6 1.8 0.87 9.5 1.2 1.6 1 1 1 2 2 2 0 CHCH domain Toxin_3 PF00537.13 EMD00496.1 - 1 9.2 3.5 2 8.3 1.4 1.9 1 1 1 2 2 2 0 Scorpion toxin-like domain Sfi1 PF08457.5 EMD00497.1 - 1e-87 294.9 88.2 1e-87 294.9 61.1 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF3074 PF11274.3 EMD00498.1 - 1.5e-52 177.8 1.9 1.5e-51 174.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) CAF-1_p150 PF11600.3 EMD00498.1 - 8e-05 22.1 45.6 0.00014 21.3 31.6 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal START PF01852.14 EMD00498.1 - 0.0051 16.1 1.9 0.0078 15.5 0.0 2.2 3 0 0 3 3 3 1 START domain CAF-1_p150 PF11600.3 EMD00499.1 - 0.0017 17.7 11.6 0.0025 17.2 8.0 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal COesterase PF00135.23 EMD00500.1 - 5.5e-86 289.3 1.3 5e-76 256.5 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD00500.1 - 4e-10 39.6 1.1 8.1e-10 38.6 0.2 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD00500.1 - 0.0011 18.7 0.4 0.0019 17.9 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DnaJ PF00226.26 EMD00503.1 - 5.5e-07 29.2 0.0 7.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EMD00503.1 - 0.0031 17.3 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 Protamine_3 PF08188.6 EMD00503.1 - 0.036 14.0 0.3 0.036 14.0 0.2 1.7 2 0 0 2 2 2 0 Spermatozal protamine family WD40 PF00400.27 EMD00505.1 - 4.6e-37 124.5 7.8 3e-10 39.5 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EMD00505.1 - 2.2e-07 30.6 2.1 3e-06 26.8 0.4 2.9 2 1 0 3 3 3 1 PQQ-like domain F-box-like PF12937.2 EMD00505.1 - 3.2e-07 29.9 0.0 8e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EMD00505.1 - 1.1e-05 23.8 0.0 0.00056 18.1 0.0 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD00505.1 - 0.0043 15.8 2.2 4.2 6.0 0.1 3.6 4 1 0 4 4 4 2 Nup133 N terminal like PQQ PF01011.16 EMD00505.1 - 0.033 13.7 0.1 1.2 8.7 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat CotJA PF11007.3 EMD00505.1 - 0.07 12.7 0.0 0.72 9.5 0.0 2.4 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) PQQ_3 PF13570.1 EMD00505.1 - 0.79 10.0 5.9 2.5e+02 2.1 0.0 6.0 6 3 1 7 7 7 0 PQQ-like domain AGTRAP PF06396.6 EMD00506.1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) PEP_mutase PF13714.1 EMD00509.1 - 2e-50 171.2 0.2 2.5e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMD00509.1 - 2.8e-13 48.9 0.1 4.3e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EMD00509.1 - 0.12 11.4 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase HgmA PF04209.8 EMD00510.1 - 1.9e-174 580.0 0.1 2.1e-174 579.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_17 PF13431.1 EMD00511.1 - 0.0036 17.3 0.8 0.22 11.7 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMD00511.1 - 0.012 15.1 0.8 0.16 11.6 1.0 2.1 1 1 1 2 2 2 0 TPR repeat Glyoxalase PF00903.20 EMD00512.1 - 1.1e-24 86.8 0.4 4.7e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMD00512.1 - 1.6e-14 53.8 0.5 5e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMD00512.1 - 8.4e-12 45.6 0.1 2.8e-05 24.6 0.1 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EMD00512.1 - 8.2e-07 29.0 0.4 0.00012 22.0 0.3 3.1 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EMD00512.1 - 2.2e-06 27.7 0.5 0.34 10.8 0.0 4.0 3 1 0 3 3 3 2 Glyoxalase-like domain MFS_1 PF07690.11 EMD00513.1 - 6e-29 100.8 25.4 6e-29 100.8 17.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily A2M_comp PF07678.9 EMD00513.1 - 0.21 10.8 0.7 0.54 9.4 0.0 1.8 2 0 0 2 2 2 0 A-macroglobulin complement component Fungal_trans PF04082.13 EMD00514.1 - 5.3e-06 25.4 1.7 0.02 13.7 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD00514.1 - 0.0013 18.6 14.7 0.0021 17.9 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 EMD00515.1 - 3.7e-12 46.3 0.0 5.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD00515.1 - 1.5e-11 44.1 0.0 2.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD00515.1 - 7.9e-07 29.1 0.0 2.3e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMD00515.1 - 0.0001 22.1 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EMD00515.1 - 0.00062 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 EMD00515.1 - 0.0045 16.8 0.5 0.0088 15.9 0.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.13 EMD00516.1 - 1.8e-44 151.7 0.0 3.9e-44 150.6 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMD00516.1 - 5.1e-16 58.6 0.0 1.2e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal FAD_binding_3 PF01494.14 EMD00517.1 - 8.7e-11 41.4 0.0 1.6e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMD00517.1 - 1.1e-05 25.6 0.0 7e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD00517.1 - 0.00041 19.3 0.1 0.0019 17.1 0.0 2.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD00517.1 - 0.012 15.6 0.1 0.032 14.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMD00517.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EMD00517.1 - 0.032 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMD00517.1 - 0.04 12.3 0.0 0.12 10.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EMD00517.1 - 0.05 12.4 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EMD00517.1 - 0.081 12.8 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMD00517.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PLDc_N PF13396.1 EMD00519.1 - 5.7e-11 41.9 7.2 1.1e-10 40.9 5.0 1.5 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal PTS_EIIC_2 PF13303.1 EMD00519.1 - 0.00028 19.8 0.3 0.00031 19.7 0.2 1.0 1 0 0 1 1 1 1 Phosphotransferase system, EIIC MARVEL PF01284.18 EMD00519.1 - 0.00071 19.4 1.2 0.0008 19.2 0.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.1 EMD00519.1 - 0.062 13.3 2.5 0.22 11.6 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF3671 PF12420.3 EMD00519.1 - 0.064 13.2 0.2 0.91 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF2207 PF09972.4 EMD00519.1 - 0.077 11.5 0.4 0.088 11.3 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pox_A14 PF05767.7 EMD00519.1 - 0.16 11.9 0.3 0.21 11.5 0.2 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF2069 PF09842.4 EMD00519.1 - 0.22 11.4 2.8 0.38 10.7 1.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) DUF3951 PF13131.1 EMD00519.1 - 1 9.1 0.1 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Peroxidase_2 PF01328.12 EMD00520.1 - 3.7e-14 52.1 0.2 1.1e-13 50.5 0.2 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 Thiolase_N PF00108.18 EMD00521.1 - 4.9e-96 320.7 0.6 7.2e-96 320.2 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMD00521.1 - 4.2e-37 126.3 1.5 4.2e-37 126.3 1.0 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMD00521.1 - 0.00039 19.9 2.0 0.001 18.6 1.0 2.0 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EMD00521.1 - 0.0011 18.5 0.4 0.067 12.8 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.14 EMD00521.1 - 0.0038 16.5 0.5 0.013 14.7 0.0 1.9 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain PAAR_motif PF05488.8 EMD00521.1 - 0.12 12.3 2.2 0.19 11.7 0.0 2.4 3 0 0 3 3 3 0 PAAR motif MFS_1 PF07690.11 EMD00522.1 - 5.4e-14 51.6 30.8 5.4e-14 51.6 21.3 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily GTP1_OBG PF01018.17 EMD00525.1 - 2.9e-37 127.7 2.8 4.1e-29 101.2 1.8 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EMD00525.1 - 3e-21 75.5 0.0 5.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD00525.1 - 7.2e-07 28.6 0.0 2.3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EMD00525.1 - 0.003 16.3 0.5 0.14 10.9 0.0 2.6 3 0 0 3 3 3 1 ArgK protein GTP_EFTU PF00009.22 EMD00525.1 - 0.0043 16.5 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EMD00525.1 - 0.024 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 EMD00525.1 - 0.068 12.6 0.0 6.9 6.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMD00525.1 - 0.086 12.7 0.1 0.25 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EMD00525.1 - 0.099 12.4 0.0 2.1 8.1 0.0 2.4 1 1 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EMD00525.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EMD00525.1 - 0.22 12.0 0.0 0.74 10.3 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein Arf PF00025.16 EMD00525.1 - 0.25 10.5 0.0 0.72 9.0 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family FtsX PF02687.16 EMD00526.1 - 0.007 16.1 2.9 0.24 11.1 1.4 2.3 2 0 0 2 2 2 1 FtsX-like permease family TMEM237 PF15383.1 EMD00526.1 - 0.14 11.3 1.0 0.17 10.9 0.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Claudin_2 PF13903.1 EMD00526.1 - 3.5 7.2 8.8 15 5.1 6.1 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MFS_1 PF07690.11 EMD00527.1 - 1.4e-26 93.0 72.2 1.3e-24 86.6 32.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.18 EMD00528.1 - 2e-116 388.3 0.9 3.9e-116 387.4 0.6 1.5 1 0 0 1 1 1 1 Kinesin motor domain XkdW PF09636.5 EMD00528.1 - 6.7 6.6 13.6 2.7 7.8 1.0 3.3 3 0 0 3 3 3 0 XkdW protein LRR_4 PF12799.2 EMD00530.1 - 1.9e-12 46.4 1.0 0.11 12.1 0.0 6.2 6 1 1 7 7 7 4 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EMD00530.1 - 6.2e-11 41.8 0.1 1.8e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EMD00530.1 - 1.8e-08 33.9 13.4 0.025 14.3 0.0 6.2 4 1 3 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EMD00530.1 - 2.2e-07 30.1 8.6 1.6 9.0 0.0 8.9 11 0 0 11 11 11 2 Leucine Rich repeat LRR_1 PF00560.28 EMD00530.1 - 2.2e-05 23.8 14.4 17 5.9 0.0 9.1 8 2 1 9 9 9 2 Leucine Rich Repeat F-box PF00646.28 EMD00530.1 - 0.00026 20.5 0.6 0.00026 20.5 0.4 2.9 3 0 0 3 3 3 1 F-box domain DSPc PF00782.15 EMD00532.1 - 3.4e-24 84.9 0.0 1.2e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMD00532.1 - 0.00061 19.2 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TIM-br_sig_trns PF09370.5 EMD00537.1 - 7.2e-137 454.7 0.5 8.1e-137 454.6 0.4 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EMD00537.1 - 9.3e-05 21.7 0.1 0.00016 20.9 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Amidohydro_2 PF04909.9 EMD00537.1 - 0.015 14.8 0.1 0.12 11.8 0.0 2.2 1 1 0 1 1 1 0 Amidohydrolase PcrB PF01884.12 EMD00537.1 - 0.44 9.7 2.1 2.6 7.2 0.0 2.5 2 1 1 3 3 3 0 PcrB family UPF0261 PF06792.6 EMD00538.1 - 6.3e-141 469.4 0.0 7.1e-141 469.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) DUF1495 PF07381.6 EMD00538.1 - 0.099 12.3 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Ku PF02735.11 EMD00539.1 - 1.9e-24 86.1 0.0 3.7e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EMD00539.1 - 3.9e-20 72.2 0.0 9.8e-20 70.9 0.0 1.7 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EMD00539.1 - 2.4e-10 40.3 0.0 1.7e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Ku C terminal domain like Ank_2 PF12796.2 EMD00540.1 - 5.1e-20 71.6 1.5 1.4e-16 60.5 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD00540.1 - 3.6e-14 52.4 1.0 3.8e-07 30.1 0.1 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EMD00540.1 - 1.4e-12 46.7 0.3 0.00012 21.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EMD00540.1 - 2e-12 46.0 0.0 0.00016 21.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMD00540.1 - 8.2e-11 42.1 0.0 0.0015 19.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TPR_20 PF14561.1 EMD00540.1 - 0.038 14.0 0.2 0.038 14.0 0.2 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat NAC PF01849.13 EMD00540.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 NAC domain DUF3385 PF11865.3 EMD00540.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Pkinase PF00069.20 EMD00541.1 - 5.7e-59 199.3 0.0 8.1e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD00541.1 - 1.7e-19 69.8 0.0 2.6e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD00541.1 - 3.5e-07 29.4 0.0 8e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMD00541.1 - 5.1e-05 23.1 0.4 0.028 14.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMD00541.1 - 6.1e-05 22.1 0.0 0.00015 20.8 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMD00541.1 - 0.0048 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 EMD00541.1 - 0.015 15.6 0.0 1.8 8.9 0.0 3.4 3 1 0 3 3 3 0 PAS domain Abhydrolase_6 PF12697.2 EMD00542.1 - 3e-18 66.5 0.1 3.5e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD00542.1 - 0.00043 20.0 0.0 0.00063 19.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3074 PF11274.3 EMD00543.1 - 9.9e-40 136.1 0.6 1.3e-39 135.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DUF362 PF04015.7 EMD00543.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Thioredoxin PF00085.15 EMD00544.1 - 0.00034 20.2 0.0 0.00042 19.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EMD00544.1 - 0.031 13.8 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Rotamase_3 PF13616.1 EMD00545.1 - 2.1e-16 60.2 0.0 3.4e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EMD00545.1 - 5.1e-16 59.1 0.0 9.5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EMD00545.1 - 1.1e-05 26.0 0.0 1.4e-05 25.7 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain LEA_5 PF00477.12 EMD00545.1 - 0.1 12.8 2.2 0.19 12.0 1.5 1.4 1 0 0 1 1 1 0 Small hydrophilic plant seed protein HET PF06985.6 EMD00546.1 - 3.3e-22 79.1 0.0 3.6e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 EMD00547.1 - 5.9e-10 38.5 7.8 1.4e-09 37.3 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type Scs3p PF10261.4 EMD00549.1 - 2.7e-67 226.3 0.4 3.2e-67 226.0 0.3 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM MFS_1 PF07690.11 EMD00550.1 - 4.3e-22 78.3 34.1 4.3e-22 78.3 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SWIB PF02201.13 EMD00551.1 - 2.4e-14 52.7 0.0 4.6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Glyco_hydro_72 PF03198.9 EMD00553.1 - 1.7e-99 332.7 0.0 2.2e-99 332.3 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Pkinase PF00069.20 EMD00554.1 - 3.4e-64 216.4 0.0 4.5e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD00554.1 - 1.8e-30 105.8 0.0 3.4e-30 104.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD00554.1 - 5.4e-05 22.2 0.1 0.00029 19.8 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EMD00554.1 - 0.0041 16.8 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD00554.1 - 0.0066 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arylsulfotran_2 PF14269.1 EMD00555.1 - 1.5e-46 158.9 2.1 2.1e-46 158.4 1.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 EMD00555.1 - 1.3e-23 83.2 47.0 1.3e-23 83.2 3.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Arylsulfotrans PF05935.6 EMD00555.1 - 2.5e-13 49.3 0.8 1.5e-12 46.7 0.5 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfotransfer_3 PF13469.1 EMD00556.1 - 9.8e-05 23.3 0.1 0.00015 22.7 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family AhpC-TSA PF00578.16 EMD00559.1 - 1.3e-32 112.1 0.0 1.8e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMD00559.1 - 5.6e-14 51.9 0.0 7.4e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EMD00559.1 - 6.4e-13 48.1 0.1 1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Fungal_trans_2 PF11951.3 EMD00560.1 - 1.2e-07 30.7 0.2 1.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD00560.1 - 2.1e-07 30.6 11.0 3.7e-07 29.9 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L15e PF00827.12 EMD00561.1 - 3e-91 304.1 10.9 3.4e-91 303.9 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 HECT PF00632.20 EMD00562.1 - 1.7e-72 244.2 0.0 2.4e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OrfB_Zn_ribbon PF07282.6 EMD00562.1 - 0.05 13.2 0.7 0.14 11.7 0.5 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain F-box-like PF12937.2 EMD00563.1 - 8.4e-07 28.6 5.0 8.5e-07 28.6 1.5 2.3 2 0 0 2 2 2 1 F-box-like RabGAP-TBC PF00566.13 EMD00564.1 - 4.6e-40 137.3 0.1 7.1e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NT-C2 PF10358.4 EMD00565.1 - 1.2e-26 92.9 0.0 1.5e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins MFS_1 PF07690.11 EMD00566.1 - 3.9e-16 58.6 62.9 7.3e-14 51.2 38.9 3.7 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD00566.1 - 1.7e-12 46.3 24.5 2.7e-12 45.6 16.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_transf_8 PF01501.15 EMD00567.1 - 4.2e-35 121.2 0.0 7.3e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EMD00567.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 EMD00567.1 - 0.032 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Rubredoxin PF00301.15 EMD00567.1 - 4.3 7.2 6.0 0.33 10.8 0.1 2.3 3 0 0 3 3 3 0 Rubredoxin Acetyltransf_11 PF13720.1 EMD00569.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 IU_nuc_hydro PF01156.14 EMD00571.1 - 7.8e-81 271.6 0.0 9.2e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Adaptin_N PF01602.15 EMD00572.1 - 1.2e-137 459.3 0.3 1.5e-137 459.1 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EMD00572.1 - 1.6e-20 73.5 0.0 4.9e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EMD00572.1 - 3e-06 27.4 0.4 0.76 10.0 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EMD00572.1 - 0.00059 19.7 2.2 20 5.6 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EMD00572.1 - 0.014 15.2 2.3 0.11 12.3 0.4 3.1 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EMD00572.1 - 0.024 15.1 0.5 7.7 7.1 0.1 4.3 3 2 2 5 5 5 0 HEAT-like repeat TIP120 PF08623.5 EMD00572.1 - 0.025 14.1 0.3 0.068 12.7 0.0 1.9 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) PTS_2-RNA PF01885.11 EMD00573.1 - 8.6e-63 211.0 0.0 1e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family TGS PF02824.16 EMD00574.1 - 5.5e-23 80.5 0.1 1.2e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMD00574.1 - 2.1e-18 66.3 0.1 5.6e-18 64.9 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD00574.1 - 2.6e-09 36.5 0.1 1.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMD00574.1 - 0.00026 20.8 0.1 0.064 13.0 0.0 2.6 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EMD00574.1 - 0.00038 19.9 2.2 1.6 8.1 0.0 4.0 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMD00574.1 - 0.0056 15.4 0.1 0.016 13.9 0.1 1.8 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EMD00574.1 - 0.029 14.8 0.0 0.11 13.0 0.0 2.0 1 1 1 2 2 2 0 Miro-like protein DUF724 PF05266.9 EMD00574.1 - 0.086 12.4 0.2 8.7 5.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HATPase_c PF02518.21 EMD00575.1 - 1.2e-23 82.9 0.0 2.9e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD00575.1 - 1.6e-22 79.6 0.0 5.6e-22 77.8 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EMD00575.1 - 2.1e-12 47.2 0.4 6.1e-06 26.5 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 EMD00575.1 - 1.4e-09 37.9 0.1 8.8e-05 22.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold HisKA PF00512.20 EMD00575.1 - 1.9e-06 27.7 0.1 5.7e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EMD00575.1 - 7.7e-05 22.4 0.0 0.00078 19.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EMD00575.1 - 0.00062 19.7 0.0 0.58 10.2 0.0 4.0 3 2 0 3 3 3 1 PAS fold PAS_8 PF13188.1 EMD00575.1 - 0.0013 18.5 0.0 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 PAS domain CDO_I PF05995.7 EMD00576.1 - 2.4e-37 127.7 0.2 6.9e-37 126.2 0.1 1.7 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EMD00576.1 - 2.9e-06 26.7 1.2 5.7e-06 25.8 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Cupin_2 PF07883.6 EMD00576.1 - 0.026 14.0 0.0 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Cupin domain PXA PF02194.10 EMD00577.1 - 2.1e-33 115.4 0.5 3e-33 114.9 0.4 1.2 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EMD00577.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Sorting nexin C terminal HTH_Tnp_Tc5 PF03221.11 EMD00578.1 - 2.9e-15 55.8 0.0 5.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EMD00578.1 - 2.3e-06 26.9 0.1 4.6e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_IS630 PF01710.11 EMD00578.1 - 0.035 13.7 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.1 EMD00578.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_4 PF13613.1 EMD00578.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.17 EMD00578.1 - 0.089 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 MarR family Aminotran_1_2 PF00155.16 EMD00580.1 - 1.9e-69 234.3 0.0 2.1e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMD00580.1 - 2.6e-06 26.7 0.0 4.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EMD00580.1 - 0.0014 17.8 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EMD00580.1 - 0.0028 16.0 0.0 0.0069 14.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMD00580.1 - 0.0033 16.2 0.0 0.012 14.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V EB1 PF03271.12 EMD00581.1 - 2.9e-17 62.4 0.5 6.4e-17 61.3 0.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EMD00581.1 - 2.3e-07 30.8 0.2 4.6e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Syja_N PF02383.13 EMD00581.1 - 0.005 15.6 0.0 0.0053 15.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF791 PF05631.9 EMD00582.1 - 1.9e-70 237.3 13.5 4.1e-70 236.2 9.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EMD00582.1 - 2.9e-20 72.2 28.1 4.2e-20 71.7 19.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3431 PF11913.3 EMD00583.1 - 9.2e-09 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3152 PF11350.3 EMD00583.1 - 0.099 12.1 0.2 0.59 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Methyltransf_24 PF13578.1 EMD00584.1 - 1.5e-07 32.2 0.0 2e-05 25.3 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD00584.1 - 0.00067 20.2 0.0 0.002 18.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Peripla_BP_2 PF01497.13 EMD00584.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein H_lectin PF09458.5 EMD00585.1 - 2e-37 126.6 0.0 4.5e-15 55.0 0.0 3.1 3 0 0 3 3 3 3 H-type lectin domain FAD_binding_7 PF03441.9 EMD00586.1 - 8.1e-83 277.8 0.0 1.1e-82 277.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMD00586.1 - 8.4e-35 119.9 0.0 1.5e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Sen15 PF09631.5 EMD00587.1 - 1.3e-24 86.3 0.0 1.8e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.3 EMD00588.1 - 3.3e-36 122.9 2.6 3.3e-36 122.9 1.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Pkinase PF00069.20 EMD00592.1 - 2.5e-60 203.8 0.0 3.1e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD00592.1 - 3.5e-34 118.0 0.0 4.7e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD00592.1 - 2.5e-09 36.5 0.0 3.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EMD00592.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL HEAT PF02985.17 EMD00595.1 - 4.6 7.5 5.5 2.7 8.3 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat Chalcone PF02431.10 EMD00596.1 - 1.1e-51 175.1 0.0 1.4e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Arginase PF00491.16 EMD00598.1 - 9.4e-32 110.4 0.8 1.1e-31 110.1 0.5 1.0 1 0 0 1 1 1 1 Arginase family MBOAT PF03062.14 EMD00600.1 - 6.3e-38 130.6 16.3 6.3e-38 130.6 11.3 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Herpes_UL49_5 PF05702.6 EMD00600.1 - 0.012 15.4 3.0 0.19 11.6 0.4 2.8 2 1 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein DUF2265 PF10023.4 EMD00602.1 - 0.027 13.6 0.1 0.03 13.4 0.1 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) PcF PF09461.5 EMD00602.1 - 0.12 12.3 1.2 0.17 11.8 0.8 1.2 1 0 0 1 1 1 0 Phytotoxin PcF protein Peptidase_M28 PF04389.12 EMD00603.1 - 8.5e-32 110.3 0.1 2.4e-31 108.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMD00603.1 - 6.1e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Sec39 PF08314.6 EMD00604.1 - 9.6e-161 536.1 0.0 1.2e-160 535.8 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF3393 PF11873.3 EMD00604.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) Abhydrolase_4 PF08386.5 EMD00605.1 - 1.8e-20 72.7 0.0 3.6e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EMD00605.1 - 9.2e-15 54.8 0.0 5.3e-08 32.7 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD00605.1 - 1.1e-09 38.5 0.3 5.3e-08 33.0 0.2 2.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD00605.1 - 3.4e-05 23.6 0.0 1.1 8.9 0.0 3.7 3 1 1 4 4 4 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD00605.1 - 0.0064 15.7 0.1 2.4 7.3 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family SnoaL_2 PF12680.2 EMD00606.1 - 0.0062 16.9 0.0 0.008 16.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SLAC1 PF03595.12 EMD00607.1 - 4.7e-63 212.8 52.3 5.3e-63 212.6 36.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DHDPS PF00701.17 EMD00610.1 - 6.5e-32 110.2 0.1 7.6e-32 110.0 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 EMD00611.1 - 6.5e-09 36.3 0.6 1.7e-08 34.9 0.4 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold BTB PF00651.26 EMD00612.1 - 0.15 12.0 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain PIG-H PF10181.4 EMD00613.1 - 2.2e-24 84.8 1.0 3.9e-24 84.0 0.7 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component BatA PF07584.6 EMD00613.1 - 0.077 13.1 3.6 0.078 13.1 0.5 2.1 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Herpes_U15 PF05613.6 EMD00613.1 - 0.19 12.1 1.4 0.36 11.2 0.2 2.0 1 1 1 2 2 2 0 Human herpesvirus U15 protein PseudoU_synth_1 PF01416.15 EMD00614.1 - 9.3e-26 90.3 0.0 1e-17 64.4 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase NmrA PF05368.8 EMD00615.1 - 1.9e-16 60.0 0.0 2.6e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD00615.1 - 1.9e-09 37.7 0.1 3.5e-09 36.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMD00615.1 - 9.7e-05 21.5 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 EMD00615.1 - 0.00024 21.5 0.1 0.00061 20.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.16 EMD00615.1 - 0.0049 16.3 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EMD00615.1 - 0.006 16.8 0.1 0.019 15.2 0.1 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.14 EMD00615.1 - 0.013 16.0 0.2 0.024 15.1 0.1 1.4 1 0 0 1 1 1 0 CoA binding domain DUF1481 PF07356.7 EMD00615.1 - 0.015 14.7 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) F420_oxidored PF03807.12 EMD00615.1 - 0.032 14.6 0.2 0.081 13.3 0.1 1.8 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 EMD00615.1 - 0.04 13.7 0.5 0.12 12.2 0.3 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMD00615.1 - 0.063 11.9 0.0 0.095 11.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EMD00615.1 - 0.073 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus His_Phos_1 PF00300.17 EMD00616.1 - 3.7e-08 33.6 0.1 2.2e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PSD4 PF07631.6 EMD00616.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) LigB PF02900.13 EMD00617.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase zf-C2H2_jaz PF12171.3 EMD00618.1 - 1.8e-09 37.4 0.4 2.9e-09 36.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD00618.1 - 3.4e-07 30.2 0.5 6.2e-07 29.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EMD00618.1 - 0.027 14.1 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.2 EMD00618.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EMD00618.1 - 0.15 11.6 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 U1 zinc finger DUF1764 PF08576.5 EMD00618.1 - 0.53 11.0 10.7 5 7.9 2.8 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RNase_H2-Ydr279 PF09468.5 EMD00618.1 - 3.8 6.6 5.5 0.27 10.3 0.6 1.4 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DNA_topoisoIV PF00521.15 EMD00619.1 - 2.4e-128 428.6 0.2 6.5e-128 427.2 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EMD00619.1 - 9.5e-36 122.6 4.9 3.2e-35 120.8 3.4 2.0 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EMD00619.1 - 4.5e-13 49.0 0.0 2e-12 46.9 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EMD00619.1 - 1.8e-09 37.2 0.0 4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase E1-E2_ATPase PF00122.15 EMD00620.1 - 4.4e-65 218.9 4.9 8.7e-65 217.9 3.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD00620.1 - 2.6e-32 111.8 6.2 2.6e-32 111.8 4.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD00620.1 - 1.7e-30 107.0 0.0 7.5e-29 101.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD00620.1 - 9.9e-17 61.7 0.0 2.3e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD00620.1 - 1.3e-16 60.2 0.0 3.1e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMD00620.1 - 3.6e-13 48.7 0.2 1.5e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD00620.1 - 3.4e-05 23.5 0.4 0.00055 19.5 0.2 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 EMD00620.1 - 0.00021 20.0 1.2 0.24 9.9 0.0 2.4 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) CoA_binding_3 PF13727.1 EMD00620.1 - 0.55 10.0 7.6 0.4 10.4 2.5 2.6 2 0 0 2 2 2 0 CoA-binding domain 2TM PF13239.1 EMD00620.1 - 1.8 8.6 15.8 1 9.4 0.0 4.0 3 1 0 3 3 3 0 2TM domain Fungal_trans PF04082.13 EMD00621.1 - 5e-31 107.5 0.0 7.6e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD00621.1 - 1.2e-09 37.9 10.9 1.8e-09 37.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMD00623.1 - 1.6e-21 76.4 35.1 4.5e-21 74.9 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PX PF00787.19 EMD00624.1 - 2.2e-14 53.2 0.0 3.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EMD00624.1 - 9.8e-09 34.7 1.5 9.8e-09 34.7 1.0 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-6_N PF09177.6 EMD00624.1 - 0.21 12.0 1.2 1.6 9.1 0.4 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal PHD PF00628.24 EMD00625.1 - 1.8e-09 37.1 7.1 3e-09 36.4 4.9 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EMD00625.1 - 0.051 13.8 0.3 0.099 12.9 0.2 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding BATS PF06968.8 EMD00626.1 - 2e-25 88.4 0.1 6.7e-25 86.7 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EMD00626.1 - 9.2e-15 55.1 0.3 1.3e-13 51.4 0.0 2.8 4 0 0 4 4 4 1 Radical SAM superfamily A_deamin PF02137.13 EMD00627.1 - 3.8e-55 187.5 0.0 4.8e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain GTP_EFTU PF00009.22 EMD00628.1 - 7.1e-58 195.1 0.1 1.1e-57 194.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMD00628.1 - 1e-36 125.0 0.0 2.7e-36 123.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMD00628.1 - 1.3e-15 57.2 2.6 1.3e-15 57.2 1.8 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EMD00628.1 - 0.00047 19.7 0.7 0.0013 18.2 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EMD00628.1 - 0.00047 20.0 0.2 0.0016 18.4 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLS PF14611.1 EMD00630.1 - 8.4e-23 80.9 0.3 1.3e-22 80.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Chlam_PMP PF02415.12 EMD00631.1 - 0.18 12.1 1.6 0.32 11.3 1.1 1.4 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat MoeA_N PF03453.12 EMD00632.1 - 3.4e-21 75.2 0.1 5.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 EMD00632.1 - 4.6e-19 68.2 0.0 8.5e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.10 EMD00632.1 - 0.047 13.6 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) DUF3824 PF12868.2 EMD00633.1 - 0.02 15.8 0.7 0.041 14.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3818 PF12825.2 EMD00634.1 - 8.7e-36 123.2 0.0 1e-21 76.9 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EMD00634.1 - 1.5e-28 99.1 0.0 1.2e-27 96.1 0.0 2.3 2 0 0 2 2 2 1 PX-associated Metal_resist PF13801.1 EMD00634.1 - 0.046 13.7 0.3 0.17 11.8 0.2 2.0 1 0 0 1 1 1 0 Heavy-metal resistance Carb_bind PF10645.4 EMD00635.1 - 2.5e-15 56.0 10.1 5.3e-15 54.9 7.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding GDE_C PF06202.9 EMD00635.1 - 0.0019 16.9 0.2 0.024 13.3 0.2 2.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase IGFL PF14653.1 EMD00635.1 - 0.024 14.6 6.3 0.09 12.8 0.5 2.5 1 1 1 2 2 2 0 Insulin growth factor-like family Abhydrolase_3 PF07859.8 EMD00636.1 - 5.4e-50 169.9 0.1 7.2e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD00636.1 - 6.4e-07 29.2 0.1 7.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMD00636.1 - 7.1e-07 28.3 0.4 1.7e-06 27.0 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EMD00636.1 - 0.0005 19.3 0.2 0.0072 15.5 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMD00636.1 - 0.0067 16.3 1.1 0.019 14.8 0.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EMD00636.1 - 0.014 14.0 0.0 0.033 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Esterase_phd PF10503.4 EMD00636.1 - 0.039 13.1 0.6 0.073 12.3 0.4 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.7 EMD00636.1 - 0.086 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Asp-B-Hydro_N PF05279.6 EMD00637.1 - 4.1 7.1 30.0 6.3 6.5 20.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1772 PF08592.6 EMD00638.1 - 1.1e-18 67.3 0.7 1.6e-18 66.7 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) IglC PF11550.3 EMD00638.1 - 0.067 12.4 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Intracellular growth locus C protein ERG4_ERG24 PF01222.12 EMD00640.1 - 1.1e-157 525.0 6.9 1.3e-157 524.7 4.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EMD00640.1 - 6.6e-05 22.3 0.4 0.00015 21.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4244 PF14029.1 EMD00640.1 - 0.11 11.5 0.1 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) DUF829 PF05705.9 EMD00641.1 - 2.7e-49 168.0 0.0 3.4e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DctQ PF04290.7 EMD00641.1 - 0.04 13.6 0.2 0.091 12.5 0.2 1.5 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component CorA PF01544.13 EMD00642.1 - 0.0051 15.8 6.5 0.006 15.6 4.5 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.11 EMD00642.1 - 0.11 10.9 2.8 0.12 10.8 2.0 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 TcpE PF12648.2 EMD00642.1 - 0.13 12.4 1.2 0.15 12.2 0.8 1.1 1 0 0 1 1 1 0 TcpE family GMC_oxred_C PF05199.8 EMD00644.1 - 2.1e-30 105.9 0.0 4e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMD00644.1 - 6.1e-27 94.5 0.0 1.9e-23 83.0 0.0 2.7 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 EMD00644.1 - 7e-05 21.8 0.0 0.00014 20.8 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMD00644.1 - 0.00025 20.9 0.0 0.00062 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EMD00644.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.9 EMD00644.1 - 0.021 14.7 0.0 0.048 13.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Arylsulfotran_2 PF14269.1 EMD00645.1 - 2.2e-42 145.2 0.3 4.8e-42 144.1 0.2 1.6 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMD00645.1 - 1.5e-09 36.9 0.7 3e-09 35.9 0.5 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ribosomal_L9_N PF01281.14 EMD00645.1 - 0.2 10.9 0.1 0.5 9.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain Abhydrolase_6 PF12697.2 EMD00646.1 - 2.8e-36 125.5 1.1 3.2e-36 125.3 0.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD00646.1 - 9.1e-19 67.9 0.0 9.7e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD00646.1 - 6.4e-15 55.1 0.3 9e-15 54.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMD00646.1 - 3.8e-06 26.6 0.3 1.7e-05 24.5 0.1 2.1 1 1 1 2 2 2 1 Putative lysophospholipase Esterase PF00756.15 EMD00646.1 - 9.3e-05 21.9 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Tannase PF07519.6 EMD00646.1 - 0.0085 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase BAAT_C PF08840.6 EMD00646.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EMD00646.1 - 0.079 12.2 0.1 0.32 10.2 0.0 1.9 2 1 0 2 2 2 0 Dienelactone hydrolase family Aminotran_1_2 PF00155.16 EMD00649.1 - 6.3e-59 199.7 0.0 7.5e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMD00649.1 - 0.0016 16.7 0.0 0.0028 15.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EMD00649.1 - 0.035 12.7 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Allinase CTP_transf_1 PF01148.15 EMD00650.1 - 8.4e-17 61.6 4.4 1.4e-14 54.4 0.6 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family PrgI PF12666.2 EMD00650.1 - 0.49 10.5 3.9 5.1 7.2 0.0 3.1 3 0 0 3 3 3 0 PrgI family protein UQ_con PF00179.21 EMD00651.1 - 1.1e-51 173.8 0.0 1.3e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD00651.1 - 9.9e-06 25.3 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMD00651.1 - 0.054 13.3 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 RWD domain Peptidase_C1_2 PF03051.10 EMD00653.1 - 3.2e-156 520.2 0.0 3.7e-156 520.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EMD00653.1 - 5.7e-07 29.6 0.1 0.012 15.5 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease DUF3331 PF11811.3 EMD00654.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) CmcI PF04989.7 EMD00655.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase PS-DH PF14765.1 EMD00656.1 - 6.6e-14 51.7 0.0 9.1e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_16 PF10294.4 EMD00657.1 - 3e-13 49.6 0.0 4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMD00657.1 - 0.00051 20.5 0.0 0.0013 19.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DUF2543 PF10820.3 EMD00657.1 - 0.008 16.1 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2543) DnaJ PF00226.26 EMD00658.1 - 7.4e-21 73.6 0.8 8.2e-21 73.5 0.6 1.0 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 EMD00660.1 - 6.3e-07 28.9 0.3 1.2e-06 28.1 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD00660.1 - 9.8e-06 25.4 0.1 6.7e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MR_MLE_C PF13378.1 EMD00661.1 - 1.5e-32 111.8 0.0 3e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EMD00661.1 - 1.2e-16 60.7 0.0 2.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EMD00661.1 - 2.3e-08 34.4 0.0 7.4e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain ADH_zinc_N PF00107.21 EMD00662.1 - 6.1e-25 87.2 0.0 1e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD00662.1 - 7.8e-18 65.5 0.0 1.8e-17 64.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD00662.1 - 1.1e-06 28.3 0.1 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sod_Fe_C PF02777.13 EMD00663.1 - 3.1e-40 136.2 0.3 8e-40 134.9 0.2 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMD00663.1 - 3.3e-31 107.3 0.8 6e-31 106.5 0.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MFS_1 PF07690.11 EMD00664.1 - 3.7e-33 114.7 21.1 5.1e-33 114.2 14.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD00664.1 - 2.9e-12 45.9 11.5 2.9e-12 45.9 8.0 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMD00664.1 - 0.0001 20.6 4.3 0.0001 20.6 3.0 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EMD00664.1 - 0.001 17.3 6.6 0.033 12.3 1.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector ATG22 PF11700.3 EMD00664.1 - 0.36 9.2 8.4 0.33 9.3 4.8 1.6 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like Cellulase PF00150.13 EMD00666.1 - 1.7e-09 37.3 0.0 5e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Cation_ATPase_N PF00690.21 EMD00668.1 - 0.089 12.2 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Se-cys_synth_N PF12390.3 EMD00669.1 - 8.6 6.5 8.0 1.3 9.1 0.0 3.5 4 0 0 4 4 4 0 Selenocysteine synthase N terminal Peptidase_C13 PF01650.13 EMD00673.1 - 7.8e-40 136.7 0.1 4.3e-24 85.1 0.1 2.1 1 1 0 2 2 2 2 Peptidase C13 family DUF4436 PF14494.1 EMD00673.1 - 0.0036 16.6 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF2401 PF10287.4 EMD00674.1 - 0.045 13.2 1.6 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative TOS1-like glycosyl hydrolase (DUF2401) RabGAP-TBC PF00566.13 EMD00675.1 - 2.8e-51 174.0 0.0 5.5e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Toxin_trans PF07952.7 EMD00675.1 - 0.23 10.3 0.4 0.4 9.5 0.2 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain DUF2400 PF09674.5 EMD00675.1 - 6.6 6.3 7.1 3.9 7.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2400) OPT PF03169.10 EMD00677.1 - 5.7e-155 517.2 13.3 6.5e-155 517.0 9.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dicistro_VP4 PF11492.3 EMD00677.1 - 0.00068 19.5 0.0 0.11 12.5 0.1 2.8 2 0 0 2 2 2 2 Cricket paralysis virus, VP4 DUF1014 PF06244.7 EMD00678.1 - 8.7e-19 67.9 16.1 4.3e-18 65.6 11.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Imm42 PF15601.1 EMD00678.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 42 Penicil_amidase PF01804.13 EMD00678.1 - 0.15 11.0 4.1 0.16 10.9 2.8 1.1 1 0 0 1 1 1 0 Penicillin amidase Patatin PF01734.17 EMD00681.1 - 2.4e-16 60.2 0.0 5.8e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.18 EMD00681.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EMD00681.1 - 0.016 14.9 0.1 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-RING_UBOX PF13445.1 EMD00681.1 - 0.023 14.4 1.9 0.057 13.1 1.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DUF258 PF03193.11 EMD00681.1 - 0.1 11.8 0.0 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 zf-C3HC4_4 PF15227.1 EMD00681.1 - 0.13 12.1 9.3 0.52 10.2 6.5 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Dynamin_N PF00350.18 EMD00681.1 - 0.18 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Dynamin family zf-RING_5 PF14634.1 EMD00681.1 - 0.44 10.3 8.7 1.3 8.8 6.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD00681.1 - 0.72 9.9 11.5 2 8.5 7.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD00681.1 - 3.1 7.6 18.4 0.081 12.7 8.2 1.8 2 0 0 2 2 1 0 Ring finger domain zf-C3HC4 PF00097.20 EMD00681.1 - 6.5 6.5 17.5 0.099 12.3 7.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_4 PF07721.9 EMD00683.1 - 0.011 16.0 2.9 0.41 11.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD00683.1 - 0.33 11.5 1.5 13 6.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.17 EMD00684.1 - 1.2e-45 149.4 20.4 0.0058 16.6 0.1 13.3 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EMD00684.1 - 1.1e-33 115.4 3.5 1.7e-07 31.3 0.0 8.0 3 1 4 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EMD00684.1 - 4.2e-11 43.0 0.3 0.00026 21.3 0.1 6.7 6 2 3 9 9 9 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMD00684.1 - 5.7e-11 42.5 16.2 0.023 15.2 0.0 9.8 7 3 4 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 EMD00684.1 - 1.4e-09 36.8 7.5 0.0031 15.9 0.3 5.6 4 1 1 6 6 6 4 Adaptin N terminal region CLASP_N PF12348.3 EMD00684.1 - 2.7e-06 26.9 1.7 0.3 10.4 0.0 4.8 3 2 1 4 4 4 2 CLASP N terminal Arm PF00514.18 EMD00684.1 - 0.00015 21.4 4.7 2.6 8.0 0.0 6.4 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EMD00684.1 - 0.00025 20.8 2.8 0.99 9.3 0.2 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) Proteasom_PSMB PF10508.4 EMD00684.1 - 0.076 11.2 2.1 0.95 7.6 0.1 2.8 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 EMD00684.1 - 0.37 10.6 6.2 7.9 6.2 0.1 4.8 3 1 3 6 6 6 0 non-SMC mitotic condensation complex subunit 1 B3_4 PF03483.12 EMD00685.1 - 3.9e-24 85.0 0.1 6.4e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EMD00685.1 - 3.4e-17 62.0 0.0 7.4e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain Fork_head PF00250.13 EMD00686.1 - 1.4e-35 121.1 0.1 2.6e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EMD00686.1 - 1.1e-08 35.0 0.0 2.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain PGA_cap PF09587.5 EMD00688.1 - 1.3e-65 221.1 0.1 1.7e-65 220.8 0.1 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap LRR_6 PF13516.1 EMD00689.1 - 1.6e-09 36.8 13.7 0.21 11.7 0.0 8.2 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like PF12937.2 EMD00689.1 - 4.8e-09 35.8 0.3 1.2e-08 34.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD00689.1 - 1.6e-08 33.9 0.6 8.4e-08 31.6 0.1 2.4 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 EMD00689.1 - 2.3e-08 33.4 11.8 0.0022 17.5 0.1 5.6 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMD00689.1 - 0.00046 19.8 15.4 9.3 6.7 0.0 7.5 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 EMD00689.1 - 0.0011 18.6 10.4 0.33 10.7 0.0 5.3 3 1 2 5 5 5 1 Leucine rich repeat PRANC PF09372.5 EMD00689.1 - 0.13 12.2 0.0 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 PRANC domain LRR_7 PF13504.1 EMD00689.1 - 0.39 11.0 18.2 82 4.1 0.0 8.2 9 0 0 9 9 9 0 Leucine rich repeat Abhydrolase_6 PF12697.2 EMD00690.1 - 3.2e-18 66.4 4.4 6.2e-18 65.5 3.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD00690.1 - 2.4e-07 30.5 0.1 6.1e-07 29.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD00690.1 - 7.1e-05 22.4 0.2 0.00013 21.5 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1295 PF06966.7 EMD00691.1 - 1.3e-41 142.4 6.2 1.6e-41 142.1 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Abhydrolase_6 PF12697.2 EMD00692.1 - 1.8e-12 47.6 3.1 2.4e-12 47.2 2.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD00692.1 - 9e-10 38.4 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LMBR1 PF04791.11 EMD00693.1 - 4.7e-28 97.9 3.0 6.5e-28 97.5 2.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Myosin_tail_1 PF01576.14 EMD00693.1 - 0.0014 16.4 0.3 0.0021 15.9 0.2 1.1 1 0 0 1 1 1 1 Myosin tail Phage_GP20 PF06810.6 EMD00693.1 - 0.017 14.6 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 EMD00693.1 - 0.035 13.7 0.1 0.035 13.7 0.1 2.9 3 1 0 3 3 3 0 IncA protein Syntaxin_2 PF14523.1 EMD00693.1 - 0.11 12.5 0.2 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Syntaxin-like protein DUF3847 PF12958.2 EMD00693.1 - 0.13 12.0 1.6 0.28 10.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) NPV_P10 PF05531.7 EMD00693.1 - 0.49 10.6 2.1 0.56 10.4 0.5 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EMD00693.1 - 9.4 5.9 7.0 1.3 8.7 1.4 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Topoisom_bac PF01131.15 EMD00695.1 - 4.5e-87 292.5 0.0 1.9e-81 273.9 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EMD00695.1 - 4.8e-18 64.9 0.0 9.6e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DEAD PF00270.24 EMD00697.1 - 1.3e-42 145.1 0.0 1.3e-41 141.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD00697.1 - 8e-27 92.9 0.1 1.8e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMD00697.1 - 0.00013 20.8 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMD00697.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CHORD PF04968.7 EMD00698.1 - 2.9e-46 155.5 21.8 9.3e-26 89.8 3.6 3.2 2 1 0 2 2 2 2 CHORD CS PF04969.11 EMD00698.1 - 8.8e-11 42.2 0.2 2e-10 41.0 0.1 1.7 2 0 0 2 2 2 1 CS domain HET PF06985.6 EMD00700.1 - 4.2e-27 94.9 0.0 6e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 EMD00701.1 - 2.7e-34 115.2 0.6 2e-07 30.4 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EMD00701.1 - 2.5e-30 103.7 0.3 1.4e-11 44.2 0.0 3.7 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD00701.1 - 2.9e-30 104.4 0.0 1.5e-14 54.1 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD00701.1 - 1.2e-29 102.1 0.0 1.1e-10 41.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD00701.1 - 1.9e-26 89.4 0.1 2.5e-05 24.1 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat NARP1 PF12569.3 EMD00702.1 - 2.4e-181 604.0 16.8 2.4e-181 604.0 11.7 2.9 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EMD00702.1 - 1.6e-18 66.7 21.4 0.00037 20.7 0.4 7.4 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EMD00702.1 - 7.6e-18 63.9 43.3 6.6e-07 28.8 0.1 7.9 9 1 2 11 11 8 6 TPR repeat TPR_14 PF13428.1 EMD00702.1 - 3e-16 58.4 23.6 0.002 18.6 0.1 11.8 7 4 5 12 12 11 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMD00702.1 - 5.7e-14 51.0 26.0 3.9e-06 26.2 0.2 8.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMD00702.1 - 6e-14 52.2 45.0 5.3e-05 23.7 0.8 9.5 9 1 2 11 11 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD00702.1 - 1.5e-13 49.5 50.0 2.5e-05 23.8 0.2 11.8 13 0 0 13 13 10 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMD00702.1 - 2e-09 37.1 15.3 0.00026 20.7 1.1 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD00702.1 - 5.1e-08 32.9 14.1 0.028 14.5 1.7 5.4 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMD00702.1 - 1.1e-07 31.4 10.2 0.079 13.1 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD00702.1 - 3.7e-07 29.4 11.5 0.0073 16.0 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD00702.1 - 1.1e-06 28.4 39.4 0.0015 18.3 0.1 9.0 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_15 PF13429.1 EMD00702.1 - 0.00011 21.3 13.4 0.0048 15.9 1.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMD00702.1 - 0.0034 17.6 8.5 0.39 11.2 0.2 5.9 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 EMD00702.1 - 0.0043 16.8 0.0 0.69 9.7 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD00702.1 - 0.012 15.3 6.4 0.72 9.7 0.1 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD00702.1 - 0.015 15.7 28.5 0.095 13.1 0.1 8.0 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_18 PF13512.1 EMD00702.1 - 0.04 13.9 6.9 2.3 8.2 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMD00702.1 - 0.13 12.2 11.2 5 7.1 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD00702.1 - 8.9 6.2 21.9 0.46 10.3 0.1 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Fapy_DNA_glyco PF01149.19 EMD00703.1 - 1.5e-23 83.3 0.0 6.5e-23 81.2 0.0 2.0 2 1 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EMD00703.1 - 4.8e-22 77.5 0.0 8.7e-22 76.6 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EMD00703.1 - 0.00053 18.6 0.0 0.0015 17.1 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) L_lac_phage_MSP PF06488.6 EMD00703.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major structural protein Ribosomal_L5_C PF00673.16 EMD00704.1 - 0.045 13.4 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 ribosomal L5P family C-terminus DUF4480 PF13715.1 EMD00706.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) Arginase PF00491.16 EMD00708.1 - 1.2e-90 303.5 0.0 1.7e-90 303.1 0.0 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMD00708.1 - 0.094 12.9 0.8 0.22 11.7 0.3 1.6 1 1 0 1 1 1 0 UPF0489 domain DAGK_cat PF00781.19 EMD00710.1 - 3.7e-24 84.6 0.1 6.3e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-U1 PF06220.7 EMD00713.1 - 5.8e-08 32.1 0.1 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 U1 zinc finger LssY_C PF14067.1 EMD00714.1 - 0.01 14.8 0.7 0.021 13.8 0.0 1.8 2 0 0 2 2 2 0 LssY C-terminus CK_II_beta PF01214.13 EMD00715.1 - 2.6e-74 248.7 0.8 3.3e-74 248.3 0.5 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RNA_pol_3_Rpc31 PF11705.3 EMD00715.1 - 0.0012 18.8 0.8 0.0019 18.1 0.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RIC1 PF07064.8 EMD00716.1 - 2.5e-79 266.4 0.2 3.4e-79 265.9 0.1 1.2 1 0 0 1 1 1 1 RIC1 Fungal_trans_2 PF11951.3 EMD00718.1 - 0.00032 19.4 0.7 0.006 15.2 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain La PF05383.12 EMD00720.1 - 8.1e-16 57.5 0.5 1.5e-15 56.7 0.4 1.4 1 0 0 1 1 1 1 La domain PUA PF01472.15 EMD00722.1 - 2e-14 53.0 0.0 4.6e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 PUA domain SET PF00856.23 EMD00724.1 - 5.7e-26 91.7 0.1 1.2e-25 90.6 0.1 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 EMD00724.1 - 1.9e-11 44.1 1.6 1.1e-10 41.6 0.2 2.6 2 1 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 EMD00724.1 - 0.0036 16.9 0.0 0.0097 15.5 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nop52 PF05997.7 EMD00725.1 - 2.5e-58 197.0 0.1 3.2e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 EMD00725.1 - 0.13 11.9 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Glyco_hydro_17 PF00332.13 EMD00726.1 - 1.2e-25 90.1 2.3 1e-23 83.8 1.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 adh_short_C2 PF13561.1 EMD00726.1 - 0.054 13.2 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PGK PF00162.14 EMD00726.1 - 0.08 11.4 0.1 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphoglycerate kinase CPL PF08144.6 EMD00727.1 - 3.8e-11 43.0 0.0 3.6e-10 39.8 0.0 2.5 2 0 0 2 2 2 1 CPL (NUC119) domain Ion_trans PF00520.26 EMD00729.1 - 8.6e-109 361.3 92.9 1.9e-36 125.2 5.6 5.6 6 0 0 6 6 6 5 Ion transport protein PKD_channel PF08016.7 EMD00729.1 - 8.6e-06 24.4 57.9 0.0014 17.1 7.6 6.1 5 1 0 5 5 5 3 Polycystin cation channel EF-hand_1 PF00036.27 EMD00729.1 - 0.0047 16.1 0.0 0.015 14.5 0.0 1.9 1 0 0 1 1 1 1 EF hand JSRP PF15312.1 EMD00729.1 - 0.065 13.2 0.0 0.3 11.0 0.0 2.2 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein RPAP2_Rtr1 PF04181.8 EMD00730.1 - 0.033 14.2 0.1 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Rtr1/RPAP2 family Asp_Glu_race PF01177.17 EMD00731.1 - 7.9e-19 68.4 0.1 9.6e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase FPN1 PF06963.7 EMD00732.1 - 2.4e-117 391.9 15.4 2.9e-117 391.6 10.7 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) PHD PF00628.24 EMD00733.1 - 9.2e-09 34.8 7.7 1.7e-08 34.0 5.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMD00733.1 - 0.0031 16.7 5.4 0.0074 15.5 3.8 1.6 1 0 0 1 1 1 1 PHD-finger PLRV_ORF5 PF01690.12 EMD00733.1 - 0.49 9.4 19.4 0.012 14.8 8.1 1.9 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein C1_1 PF00130.17 EMD00733.1 - 0.7 9.6 8.1 0.089 12.5 2.5 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF572 PF04502.8 EMD00733.1 - 8.1 5.5 36.3 1.1 8.4 20.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) RNA_pol_Rpb4 PF03874.11 EMD00735.1 - 5.7e-09 36.0 4.4 2.4e-08 34.0 3.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 Myb_DNA-binding PF00249.26 EMD00735.1 - 0.09 12.8 0.1 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain HAP1_N PF04849.8 EMD00735.1 - 0.36 9.7 6.5 2.1 7.2 1.0 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region ABC_membrane PF00664.18 EMD00736.1 - 6.6e-32 111.0 13.5 8.2e-32 110.7 9.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMD00736.1 - 1.2e-30 106.5 0.0 2.2e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMD00736.1 - 2.7e-05 23.5 0.0 7.1e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EMD00736.1 - 0.0028 17.5 1.0 0.022 14.6 0.2 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EMD00736.1 - 0.029 14.3 0.1 0.58 10.0 0.0 2.3 2 1 0 3 3 3 0 AAA domain Imm35 PF15581.1 EMD00736.1 - 0.04 13.9 0.2 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 35 AAA_29 PF13555.1 EMD00736.1 - 0.098 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nop PF01798.13 EMD00738.1 - 8.1e-55 184.2 1.4 2e-54 182.9 1.0 1.7 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMD00738.1 - 2.2e-26 91.3 0.1 3.8e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EMD00738.1 - 7.1e-22 77.3 2.1 1.6e-21 76.2 1.4 1.6 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF760 PF05542.6 EMD00738.1 - 0.086 13.0 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF760) Actin PF00022.14 EMD00739.1 - 2e-20 72.6 0.0 4.3e-19 68.2 0.0 2.2 2 1 0 2 2 2 2 Actin COG5 PF10392.4 EMD00740.1 - 0.0032 17.4 0.2 0.0088 15.9 0.1 1.8 1 0 0 1 1 1 1 Golgi transport complex subunit 5 COG7 PF10191.4 EMD00740.1 - 0.0047 14.9 0.0 0.011 13.7 0.0 1.5 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) Baculo_PEP_C PF04513.7 EMD00740.1 - 0.039 13.7 2.1 0.087 12.6 1.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 EMD00740.1 - 0.57 10.2 2.8 4 7.5 0.1 3.1 3 1 0 3 3 3 0 Proteins of 100 residues with WXG PARP PF00644.15 EMD00741.1 - 2.4e-10 40.1 0.1 5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EMD00741.1 - 4.2e-06 26.2 0.0 9.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme XPG_I PF00867.13 EMD00744.1 - 6.8e-24 83.7 0.0 1.7e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMD00744.1 - 6.6e-08 32.7 0.0 1.6e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EMD00744.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing TPT PF03151.11 EMD00745.1 - 1e-20 73.9 8.0 1e-20 73.9 5.6 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMD00745.1 - 2.9e-13 49.4 16.9 9.4e-13 47.7 11.7 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMD00745.1 - 1.1 9.2 30.6 0.14 12.2 8.0 2.7 3 0 0 3 3 3 0 EamA-like transporter family Glyco_hydro_3 PF00933.16 EMD00746.1 - 1.6e-82 276.8 0.0 2.4e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD00746.1 - 8.7e-66 221.6 0.0 2.5e-65 220.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD00746.1 - 1.8e-21 75.8 0.1 4.1e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EMD00746.1 - 6e-09 35.6 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GFO_IDH_MocA PF01408.17 EMD00747.1 - 1.1e-18 67.8 0.0 2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.11 EMD00748.1 - 3.2e-31 108.3 15.2 3.2e-31 108.3 10.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD00748.1 - 1.9e-08 33.0 1.1 1.9e-08 33.0 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Calici_coat PF00915.15 EMD00752.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Calicivirus coat protein zf-BED PF02892.10 EMD00753.1 - 0.011 15.4 2.3 0.011 15.4 1.6 1.8 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 EMD00753.1 - 0.13 12.6 2.3 4 7.8 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD00753.1 - 0.46 10.9 6.6 0.12 12.7 2.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD00753.1 - 3.8 8.0 9.4 0.37 11.2 2.8 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_11 PF13414.1 EMD00754.1 - 7.5e-49 163.2 31.3 7e-17 60.8 0.1 5.7 2 2 3 6 6 6 6 TPR repeat TPR_1 PF00515.23 EMD00754.1 - 7.5e-41 136.1 23.0 1.5e-09 37.0 0.0 8.4 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMD00754.1 - 1.4e-38 127.6 26.9 1.8e-07 30.5 0.1 8.4 8 1 1 9 9 8 7 Tetratricopeptide repeat DnaJ PF00226.26 EMD00754.1 - 2.1e-28 97.8 3.0 4.8e-28 96.6 1.4 2.2 2 0 0 2 2 1 1 DnaJ domain TPR_16 PF13432.1 EMD00754.1 - 6.5e-28 96.7 18.3 1e-07 32.3 0.0 5.7 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMD00754.1 - 2.7e-24 83.4 14.9 1e-05 25.7 0.1 7.5 5 3 2 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMD00754.1 - 3.1e-20 72.2 24.1 8.8e-05 22.7 0.2 5.9 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMD00754.1 - 4.4e-20 71.3 23.0 5.9e-06 26.1 0.1 6.0 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 EMD00754.1 - 7.6e-19 65.9 13.5 0.0029 17.2 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.1 EMD00754.1 - 3.5e-17 61.5 16.0 0.002 18.4 0.1 7.6 7 1 1 8 8 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMD00754.1 - 4e-17 60.6 15.0 0.00023 20.6 0.0 7.4 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMD00754.1 - 1.2e-16 59.4 26.4 0.0081 16.2 0.7 8.6 9 1 0 9 9 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EMD00754.1 - 7e-14 51.7 13.3 6.1e-05 23.0 3.5 4.0 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EMD00754.1 - 1.3e-08 34.5 16.0 0.0027 17.5 0.0 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMD00754.1 - 1.5e-08 34.3 19.8 0.46 10.5 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_15 PF13429.1 EMD00754.1 - 5e-07 29.0 11.0 0.16 11.0 0.0 4.7 2 2 1 4 4 4 4 Tetratricopeptide repeat BTAD PF03704.12 EMD00754.1 - 5.5e-07 29.9 10.4 0.1 12.8 0.1 4.9 3 1 1 4 4 4 2 Bacterial transcriptional activator domain TPR_4 PF07721.9 EMD00754.1 - 1.7e-06 27.9 13.0 0.064 13.7 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD00754.1 - 4.1e-06 26.5 5.8 0.17 11.7 0.0 4.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 EMD00754.1 - 0.00026 20.7 1.9 9.3 6.4 0.0 5.7 7 0 0 7 7 5 0 PPR repeat TPR_20 PF14561.1 EMD00754.1 - 0.00041 20.4 15.8 0.11 12.6 0.7 5.1 3 3 1 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 EMD00754.1 - 0.0016 18.2 12.6 2 8.3 0.4 5.0 2 1 2 4 4 4 1 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 EMD00754.1 - 0.012 15.9 8.6 3.1 8.0 0.0 4.1 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation NARP1 PF12569.3 EMD00754.1 - 0.012 14.4 9.9 0.014 14.1 0.0 3.7 2 2 1 3 3 3 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.2 EMD00754.1 - 0.044 13.6 5.9 42 3.9 0.3 5.2 3 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) DUF3597 PF12200.3 EMD00754.1 - 0.053 13.9 3.6 0.066 13.5 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF3597) TOM20_plant PF06552.7 EMD00754.1 - 0.055 13.0 0.9 0.66 9.5 0.1 2.7 2 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Rapsyn_N PF10579.4 EMD00754.1 - 0.16 11.7 1.7 3.6 7.4 0.0 3.7 3 3 1 4 4 3 0 Rapsyn N-terminal myristoylation and linker region TPR_3 PF07720.7 EMD00754.1 - 0.73 9.6 7.6 23 4.9 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMD00754.1 - 4.1 7.3 20.5 1.7 8.5 0.2 4.7 3 2 0 5 5 5 0 Tetratricopeptide repeat DUF3366 PF11846.3 EMD00754.1 - 5.5 6.8 8.4 12 5.7 2.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) KH_1 PF00013.24 EMD00755.1 - 5.8e-40 134.7 9.8 9.5e-16 57.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMD00755.1 - 1.2e-31 107.7 13.2 8.5e-13 47.6 1.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMD00755.1 - 6.3e-11 41.6 12.3 0.00074 19.0 0.7 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 EMD00755.1 - 4.5e-08 32.6 5.8 0.047 13.3 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMD00755.1 - 6.2e-05 22.7 4.3 0.29 10.9 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 EMD00755.1 - 0.062 12.7 0.3 2.9 7.3 0.0 2.7 3 0 0 3 3 3 0 dUTPase NmrA PF05368.8 EMD00756.1 - 7.9e-41 139.8 0.0 3.6e-39 134.3 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD00756.1 - 1.4e-08 34.9 0.0 3.3e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMD00756.1 - 0.00024 19.8 0.0 0.00032 19.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fringe PF02434.11 EMD00757.1 - 3.4e-08 33.0 0.1 6.8e-08 32.0 0.1 1.5 1 1 0 1 1 1 1 Fringe-like 2OG-FeII_Oxy_3 PF13640.1 EMD00758.1 - 1.7e-08 34.8 0.0 2.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMD00758.1 - 1.6e-05 25.0 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMD00758.1 - 0.00015 21.2 0.0 0.00043 19.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EBP PF05241.7 EMD00760.1 - 6.4e-05 22.0 7.6 0.00023 20.2 5.3 1.8 1 1 0 1 1 1 1 Emopamil binding protein MIP PF00230.15 EMD00761.1 - 1e-50 172.3 2.9 1.4e-50 171.9 2.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_S7e PF01251.13 EMD00762.1 - 3.3e-80 268.0 0.1 3.7e-80 267.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Zn_clus PF00172.13 EMD00763.1 - 1e-08 34.9 11.9 2.2e-08 33.8 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMD00764.1 - 3.3e-33 114.8 78.8 1.7e-31 109.2 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMD00764.1 - 0.00014 21.5 9.4 0.0011 18.7 1.3 3.7 3 1 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.19 EMD00764.1 - 0.00079 18.1 7.0 0.00079 18.1 4.9 3.6 2 2 2 4 4 4 4 Sugar (and other) transporter SF3b10 PF07189.6 EMD00766.1 - 1.1e-34 118.1 0.0 1.2e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.14 EMD00767.1 - 2.7e-42 144.3 0.0 3.5e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 MAGE family Cut8_N PF14482.1 EMD00767.1 - 0.7 9.9 4.3 0.95 9.5 0.1 3.0 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Ras PF00071.17 EMD00768.1 - 1.3e-57 193.7 0.0 1.5e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD00768.1 - 2.2e-20 73.2 0.0 4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD00768.1 - 1.8e-14 53.3 0.0 2.8e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD00768.1 - 3.1e-09 36.3 0.0 3.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMD00768.1 - 1.3e-07 31.2 0.0 3.1e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMD00768.1 - 0.00013 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMD00768.1 - 0.031 14.2 0.0 0.046 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EMD00769.1 - 0.00024 20.5 0.1 0.0044 16.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 EMD00769.1 - 0.00058 18.8 0.3 0.071 12.0 0.1 2.2 2 0 0 2 2 2 2 Rad51 KaiC PF06745.8 EMD00769.1 - 0.041 12.9 0.0 0.88 8.6 0.0 2.1 2 0 0 2 2 2 0 KaiC DIOX_N PF14226.1 EMD00770.1 - 1.1e-28 100.0 0.0 1.6e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMD00770.1 - 4.7e-18 65.3 0.0 8e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UDPGT PF00201.13 EMD00771.1 - 5e-05 22.0 0.0 0.079 11.5 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Lac_bphage_repr PF06543.7 EMD00771.1 - 0.019 14.5 0.8 1 8.9 0.3 2.4 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor DUF1687 PF07955.6 EMD00771.1 - 0.027 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Glyco_tran_28_C PF04101.11 EMD00771.1 - 0.094 12.3 0.1 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain Glutaredoxin PF00462.19 EMD00772.1 - 2e-19 69.3 0.0 2.6e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EMD00772.1 - 0.0007 19.8 0.0 0.00087 19.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 EMD00772.1 - 0.0011 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EMD00772.1 - 0.0056 16.8 0.1 0.014 15.5 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.15 EMD00772.1 - 0.034 13.7 0.2 0.38 10.2 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.1 EMD00772.1 - 0.043 13.3 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.15 EMD00772.1 - 0.05 13.2 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.1 EMD00772.1 - 0.07 12.5 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF1857 PF08982.6 EMD00773.1 - 7.8e-31 106.6 0.0 8.7e-31 106.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Glyco_transf_90 PF05686.7 EMD00774.1 - 3.8e-17 62.0 7.8 1.1e-13 50.6 5.1 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 zf-C2H2 PF00096.21 EMD00777.1 - 4.7e-06 26.6 17.5 1.6e-05 24.9 2.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD00777.1 - 2.9e-05 24.1 3.8 2.9e-05 24.1 2.7 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMD00777.1 - 0.00042 20.3 1.0 0.00096 19.2 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMD00777.1 - 0.00058 20.0 0.9 0.00058 20.0 0.6 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 EMD00777.1 - 0.12 12.6 0.8 0.34 11.1 0.5 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EMD00777.1 - 0.3 11.4 6.6 0.21 11.9 1.4 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger DUF4098 PF13345.1 EMD00779.1 - 4.2e-05 23.4 10.5 0.28 11.1 0.1 4.5 4 1 0 4 4 4 3 Domain of unknown function (DUF4098) Pkinase PF00069.20 EMD00780.1 - 6.9e-40 136.8 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD00780.1 - 1.6e-32 112.6 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Spindle_Spc25 PF08234.7 EMD00781.1 - 2.9e-18 65.6 0.0 7.4e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 EMD00781.1 - 0.0056 15.3 2.5 0.0079 14.8 1.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3829 PF12889.2 EMD00781.1 - 0.022 13.9 4.3 0.031 13.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) RE_Alw26IDE PF09665.5 EMD00781.1 - 0.064 11.9 2.6 0.088 11.5 1.8 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Mnd1 PF03962.10 EMD00781.1 - 0.74 9.4 7.3 0.92 9.1 4.5 1.6 1 1 0 1 1 1 0 Mnd1 family E1-E2_ATPase PF00122.15 EMD00784.1 - 4.4e-43 146.9 4.7 9e-43 145.9 3.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD00784.1 - 9.6e-34 116.4 6.8 1.9e-28 99.2 1.1 3.7 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD00784.1 - 2e-32 113.3 0.0 2.7e-31 109.6 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD00784.1 - 1.5e-20 72.9 0.0 6.2e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMD00784.1 - 3.2e-13 50.2 0.0 7.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD00784.1 - 4e-11 42.2 0.0 9.2e-11 41.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD00784.1 - 6.9e-06 25.8 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SYF2 PF08231.7 EMD00784.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 SYF2 splicing factor Reticulon PF02453.12 EMD00785.1 - 1.6e-32 112.4 6.5 2.7e-32 111.7 4.5 1.4 1 0 0 1 1 1 1 Reticulon PRT_C PF08372.5 EMD00785.1 - 0.11 12.0 0.2 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal FUSC_2 PF13515.1 EMD00785.1 - 9.7 6.1 12.0 11 5.9 2.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like 5_nucleotid_C PF02872.13 EMD00786.1 - 2.1e-34 118.7 0.0 3.5e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EMD00786.1 - 1.6e-08 34.1 0.0 2.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homeobox_KN PF05920.6 EMD00787.1 - 2.6e-12 46.2 0.4 5.7e-12 45.1 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 EMD00787.1 - 2.3e-06 27.3 0.8 8.9e-06 25.4 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Homeobox PF00046.24 EMD00787.1 - 0.0012 18.3 0.3 0.0036 16.9 0.2 1.9 1 0 0 1 1 1 1 Homeobox domain Zn_clus PF00172.13 EMD00787.1 - 0.0064 16.3 7.2 0.025 14.5 5.0 2.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HA PF03457.9 EMD00787.1 - 0.092 12.8 2.9 0.17 11.9 0.1 2.9 2 0 0 2 2 2 0 Helicase associated domain zf-C2H2 PF00096.21 EMD00787.1 - 0.81 10.1 26.7 0.076 13.3 1.1 4.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type Aldolase_II PF00596.16 EMD00788.1 - 9.9e-48 162.1 0.1 1.2e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AAA PF00004.24 EMD00789.1 - 1.5e-14 54.3 0.0 3.3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMD00789.1 - 1.5e-09 38.0 0.1 9.5e-09 35.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD00789.1 - 9.5e-07 29.0 0.0 7.8e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain BAH PF01426.13 EMD00789.1 - 3e-05 23.7 0.0 7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.1 EMD00789.1 - 0.002 17.8 0.9 0.0064 16.2 0.6 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EMD00789.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMD00789.1 - 0.026 15.3 0.0 0.11 13.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EMD00789.1 - 0.043 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMD00789.1 - 0.044 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EMD00789.1 - 0.058 13.5 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase DUF2075 PF09848.4 EMD00789.1 - 0.081 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EMD00789.1 - 0.11 12.1 0.0 0.66 9.6 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 EMD00789.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 EMD00789.1 - 0.13 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 EMD00789.1 - 0.25 10.2 0.0 0.41 9.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase zf-C2H2_2 PF12756.2 EMD00791.1 - 1.9e-05 24.7 0.2 3.2e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) CDC45 PF02724.9 EMD00796.1 - 4.8e-198 659.1 14.7 2.1e-196 653.7 10.2 3.0 1 1 0 1 1 1 1 CDC45-like protein Peptidase_M17_N PF02789.12 EMD00796.1 - 0.038 13.7 1.3 0.075 12.7 0.2 2.1 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain NUDIX PF00293.23 EMD00799.1 - 2.4e-20 72.5 0.0 2.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain B9-C2 PF07162.6 EMD00799.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein Helicase_C PF00271.26 EMD00800.1 - 1e-21 76.5 0.0 7.8e-18 64.1 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EMD00800.1 - 7.5e-19 67.8 0.0 1.6e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EMD00800.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain tRNA-synt_1 PF00133.17 EMD00801.1 - 1.1e-197 657.7 0.0 6.1e-196 652.0 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMD00801.1 - 2.3e-23 82.6 0.0 1.2e-21 77.0 0.0 2.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMD00801.1 - 9.6e-19 67.2 0.0 1.6e-06 27.0 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EMD00801.1 - 0.013 14.6 0.0 0.029 13.4 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PAS_9 PF13426.1 EMD00802.1 - 7.3e-20 71.2 0.0 2e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EMD00802.1 - 4.8e-06 26.3 0.0 1.5e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EMD00802.1 - 0.0039 17.2 0.1 0.11 12.5 0.0 3.1 4 0 0 4 4 4 1 PAS fold Catalase PF00199.14 EMD00803.1 - 1e-63 215.3 0.0 1.4e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Catalase zf-C2H2 PF00096.21 EMD00804.1 - 1.5e-10 40.7 15.8 0.00099 19.3 0.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD00804.1 - 4.6e-09 35.9 13.4 0.0073 16.5 1.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD00804.1 - 7.3e-05 22.8 14.2 0.0039 17.3 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMD00804.1 - 0.028 14.5 0.4 0.028 14.5 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMD00804.1 - 0.052 13.6 10.2 0.11 12.5 0.9 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF3583 PF12126.3 EMD00805.1 - 0.099 11.6 3.8 0.12 11.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) zf-C2H2 PF00096.21 EMD00807.1 - 7.6e-09 35.4 13.4 0.0067 16.7 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD00807.1 - 1.2e-05 25.3 19.1 0.027 14.7 0.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger Zn_ribbon_recom PF13408.1 EMD00807.1 - 4.7 7.5 11.3 27 5.1 6.1 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2H2_2 PF12756.2 EMD00807.1 - 6.1 7.0 11.1 1.1 9.4 0.2 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Band_7 PF01145.20 EMD00809.1 - 1.4e-30 106.4 0.3 2.9e-30 105.4 0.2 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMD00809.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family UPF0060 PF02694.10 EMD00811.1 - 0.27 11.2 2.0 0.42 10.6 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family Peptidase_C14 PF00656.17 EMD00812.1 - 0.0072 16.0 0.1 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Glyco_hydro_101 PF12905.2 EMD00812.1 - 0.084 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase Raptor_N PF14538.1 EMD00812.1 - 0.43 10.4 1.9 3.4 7.5 1.3 2.2 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Abhydrolase_6 PF12697.2 EMD00813.1 - 3.7e-09 36.7 4.3 5.6e-09 36.2 3.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMD00813.1 - 6.5e-09 35.6 0.0 5e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD00813.1 - 2e-05 24.3 0.0 6.1e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMD00813.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 EMD00813.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 EMD00813.1 - 0.023 14.2 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 EMD00813.1 - 0.065 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EMD00813.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 EMD00813.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1183 PF06682.7 EMD00814.1 - 0.00049 19.7 1.7 0.00049 19.7 1.2 5.3 3 2 2 5 5 5 3 Protein of unknown function (DUF1183) Inhibitor_I78 PF11720.3 EMD00815.1 - 1.7e-11 43.6 0.0 2.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EMD00815.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Potato inhibitor I family SURF4 PF02077.10 EMD00817.1 - 4.7e-92 308.1 7.1 5.3e-92 307.9 4.9 1.0 1 0 0 1 1 1 1 SURF4 family DUF3325 PF11804.3 EMD00817.1 - 0.011 15.6 7.5 0.011 15.6 5.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3325) HR_lesion PF05514.6 EMD00817.1 - 0.24 11.2 7.9 0.26 11.1 1.6 3.2 3 1 0 3 3 3 0 HR-like lesion-inducing Peptidase_A24 PF01478.13 EMD00817.1 - 5.7 7.1 16.4 0.35 11.0 1.0 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family Nup84_Nup100 PF04121.8 EMD00818.1 - 1.1e-54 185.3 13.5 2.1e-53 181.1 9.3 2.8 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Peptidase_S11 PF00768.15 EMD00818.1 - 0.0037 16.5 0.2 0.0086 15.3 0.2 1.6 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase MutS_III PF05192.13 EMD00818.1 - 0.75 9.5 5.4 2.9 7.6 0.8 3.1 2 2 0 2 2 2 0 MutS domain III DUF3336 PF11815.3 EMD00819.1 - 2.7e-32 111.2 0.0 2.9e-31 107.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMD00819.1 - 9.3e-11 42.0 0.2 8.9e-10 38.8 0.1 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase V-SNARE_C PF12352.3 EMD00820.1 - 3.3e-14 52.6 0.4 3.3e-14 52.6 0.3 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus MtrG PF04210.8 EMD00820.1 - 0.02 14.5 0.1 0.052 13.2 0.0 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Syntaxin-6_N PF09177.6 EMD00820.1 - 0.025 14.9 4.4 0.025 14.9 3.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Exotox-A_target PF09102.5 EMD00820.1 - 0.061 12.8 0.4 0.1 12.1 0.3 1.4 1 1 0 1 1 1 0 Exotoxin A, targeting LIN37 PF15306.1 EMD00820.1 - 0.18 11.8 5.4 0.35 10.8 3.7 1.5 1 0 0 1 1 1 0 LIN37 TBPIP PF07106.8 EMD00820.1 - 0.35 10.4 4.4 0.38 10.2 2.5 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HrpB7 PF09486.5 EMD00820.1 - 0.46 10.4 19.1 0.11 12.4 2.0 3.5 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) PDDEXK_1 PF12705.2 EMD00820.1 - 1.1 8.5 4.2 1.4 8.2 2.6 1.4 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Laminin_II PF06009.7 EMD00820.1 - 3.1 7.5 7.7 14 5.4 4.1 2.7 2 1 0 2 2 2 0 Laminin Domain II RWD PF05773.17 EMD00821.1 - 7.8e-23 80.5 1.0 1.3e-22 79.7 0.7 1.4 1 0 0 1 1 1 1 RWD domain DBINO PF13892.1 EMD00821.1 - 0.42 10.6 12.0 0.75 9.8 8.3 1.4 1 0 0 1 1 1 0 DNA-binding domain TPR_12 PF13424.1 EMD00822.1 - 3.4e-13 49.3 0.7 2.4e-07 30.5 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD00822.1 - 3.1e-10 40.2 4.0 0.0022 18.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD00822.1 - 1e-09 38.7 1.7 0.00012 22.6 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD00822.1 - 2.1e-09 36.5 0.0 6.4e-05 22.5 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD00822.1 - 3e-08 33.6 10.6 0.029 14.9 0.0 5.3 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD00822.1 - 5e-08 32.4 1.2 3e-05 23.5 0.0 3.7 4 1 1 5 5 5 1 TPR repeat TPR_8 PF13181.1 EMD00822.1 - 5.8e-08 31.9 0.0 3.3e-05 23.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD00822.1 - 8.5e-07 28.3 2.6 0.00024 20.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMD00822.1 - 3.1e-05 23.3 0.0 0.0017 17.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD00822.1 - 0.00028 21.1 8.9 0.54 10.8 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD00822.1 - 0.00081 19.4 0.1 2.3 8.3 0.0 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMD00822.1 - 0.0023 17.9 0.0 15 6.1 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMD00822.1 - 0.0055 16.7 3.7 1.4 9.1 0.1 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 EMD00822.1 - 0.0081 16.1 4.1 0.41 10.5 0.1 3.2 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMD00822.1 - 0.44 10.4 3.0 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMD00822.1 - 2.5 8.1 7.0 3.5 7.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat HMG_box PF00505.14 EMD00825.1 - 1.7e-07 31.3 0.7 1.9e-07 31.2 0.5 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box ATP-synt_10 PF05176.9 EMD00827.1 - 1.7e-72 243.7 0.0 2.2e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein BRCT PF00533.21 EMD00828.1 - 2e-36 123.9 0.2 5.5e-12 45.6 0.1 6.6 7 0 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMD00828.1 - 1.9e-33 114.1 1.6 6.7e-21 73.9 0.3 4.8 4 0 0 4 4 4 3 twin BRCT domain GIY-YIG PF01541.19 EMD00828.1 - 0.038 14.3 1.5 0.065 13.6 0.0 2.1 3 0 0 3 3 3 0 GIY-YIG catalytic domain CN_hydrolase PF00795.17 EMD00829.1 - 7.8e-28 97.0 0.0 1.4e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DHO_dh PF01180.16 EMD00830.1 - 1.3e-19 70.3 0.0 1.6e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 EMD00830.1 - 0.3 10.1 4.7 0.53 9.3 3.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase zf-met PF12874.2 EMD00832.1 - 1.8e-05 24.7 0.6 3.7e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EMD00832.1 - 0.049 12.8 0.9 0.094 11.9 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF1168 PF06658.7 EMD00833.1 - 7.5e-40 135.7 8.6 9.7e-40 135.3 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) SUR7 PF06687.7 EMD00834.1 - 3.3e-13 49.6 19.0 8.8e-13 48.3 12.5 1.8 1 1 1 2 2 2 1 SUR7/PalI family DUF3816 PF12822.2 EMD00834.1 - 0.009 15.9 4.3 0.009 15.9 3.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3816) DUF962 PF06127.6 EMD00834.1 - 0.026 14.3 0.8 0.26 11.1 0.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF3733 PF12534.3 EMD00834.1 - 0.23 10.7 1.7 10 5.4 0.1 2.6 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Hum_adeno_E3A PF05393.6 EMD00834.1 - 0.31 10.7 2.9 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein RCR PF12273.3 EMD00834.1 - 0.49 10.9 0.1 0.49 10.9 0.1 2.1 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Claudin_2 PF13903.1 EMD00834.1 - 0.52 9.9 17.0 0.39 10.3 9.8 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF973 PF06157.6 EMD00834.1 - 0.87 8.4 8.3 1.4 7.8 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Orbi_NS3 PF01616.11 EMD00834.1 - 4.2 6.2 5.0 2.4 7.0 0.4 2.5 2 1 1 3 3 3 0 Orbivirus NS3 RseC_MucC PF04246.7 EMD00834.1 - 9 5.8 8.1 1.7 8.1 1.7 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Arginase PF00491.16 EMD00836.1 - 1.3e-78 264.1 1.3 1.6e-78 263.8 0.9 1.0 1 0 0 1 1 1 1 Arginase family Glyco_hydro_4C PF11975.3 EMD00836.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Peptidase_M49 PF03571.10 EMD00837.1 - 1.5e-228 759.3 0.0 1.8e-228 759.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF600 PF04634.7 EMD00837.1 - 0.02 14.9 0.6 0.094 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF600 Death PF00531.17 EMD00837.1 - 0.033 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Death domain SOG2 PF10428.4 EMD00838.1 - 0.95 8.0 9.8 1.2 7.6 6.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NAD_binding_5 PF07994.7 EMD00839.1 - 1.1e-109 366.4 0.0 1.4e-109 366.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EMD00839.1 - 1.3e-46 157.0 0.3 2.1e-46 156.3 0.2 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase His_Phos_1 PF00300.17 EMD00840.1 - 7.1e-32 110.6 0.0 9.5e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EMD00840.1 - 9.6e-06 25.1 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) EAF PF09816.4 EMD00841.1 - 2.5e-07 30.6 0.1 5.3e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Ank_2 PF12796.2 EMD00842.1 - 6.9e-75 247.4 27.8 3.4e-15 56.1 1.1 5.7 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EMD00842.1 - 5.1e-46 152.2 13.7 1.1e-07 31.3 0.2 10.6 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 EMD00842.1 - 5.8e-37 124.8 17.3 3.1e-09 36.7 0.6 8.7 3 3 6 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD00842.1 - 7e-37 125.1 8.7 9.7e-08 32.3 0.3 7.4 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD00842.1 - 1.4e-35 117.6 9.7 0.00018 21.4 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat DUF948 PF06103.6 EMD00842.1 - 0.061 13.1 0.4 9.8 6.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_C97 PF05903.9 EMD00843.1 - 5.7e-33 113.8 0.0 7.4e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EMD00843.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.7 EMD00843.1 - 0.072 13.0 0.2 0.26 11.2 0.1 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF778) Iso_dh PF00180.15 EMD00844.1 - 2.6e-86 289.7 0.0 3.1e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HATPase_c PF02518.21 EMD00847.1 - 1.2e-23 82.9 0.0 2.5e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD00847.1 - 1e-21 77.0 4.7 9.1e-21 73.9 0.3 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMD00847.1 - 1.5e-11 44.1 0.2 3e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EMD00847.1 - 8.2e-07 29.0 0.1 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EMD00847.1 - 0.0043 17.0 0.0 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EMD00847.1 - 0.0094 16.3 0.0 0.039 14.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EMD00847.1 - 0.085 12.6 0.0 0.71 9.6 0.0 2.5 2 1 1 3 3 3 0 PAS fold Mago_nashi PF02792.9 EMD00848.1 - 1.8e-75 251.4 0.4 2.1e-75 251.2 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Phage_portal_2 PF05136.8 EMD00848.1 - 0.09 11.2 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein, lambda family Adaptin_N PF01602.15 EMD00849.1 - 1.8e-95 320.2 8.0 3e-95 319.5 5.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 EMD00849.1 - 5.3e-60 201.1 1.3 1.3e-59 199.8 0.9 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 EMD00849.1 - 7.9e-60 200.2 0.0 2.2e-59 198.8 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 EMD00849.1 - 1.1e-11 44.8 6.3 4e-05 23.8 0.0 4.3 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EMD00849.1 - 1.9e-05 24.5 6.1 0.0052 16.6 0.0 3.9 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMD00849.1 - 0.00023 20.9 0.9 0.21 11.7 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EMD00849.1 - 0.0025 18.2 0.7 0.58 10.7 0.0 4.1 4 0 0 4 4 4 1 HEAT-like repeat Ribosomal_L13 PF00572.13 EMD00850.1 - 1.2e-26 93.3 0.0 3.5e-26 91.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 DUF1604 PF07713.8 EMD00851.1 - 1.3e-33 114.6 5.4 1.8e-32 110.9 3.7 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EMD00851.1 - 7.6e-07 28.8 3.9 3.5e-06 26.6 1.1 2.9 2 0 0 2 2 2 1 G-patch domain Pkinase PF00069.20 EMD00852.1 - 1.7e-77 260.0 0.0 3e-77 259.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD00852.1 - 2.8e-39 134.7 0.0 9.7e-39 132.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EMD00852.1 - 2.3e-16 58.9 0.2 3.5e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EMD00852.1 - 3.1e-05 23.1 0.0 0.00023 20.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMD00852.1 - 5.2e-05 22.4 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMD00852.1 - 0.0046 16.7 0.1 0.071 12.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EMD00852.1 - 0.02 14.0 0.1 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EMD00852.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_L29 PF00831.18 EMD00853.1 - 3.7e-19 68.1 2.8 7.4e-19 67.1 1.9 1.5 1 0 0 1 1 1 1 Ribosomal L29 protein SPATA24 PF15175.1 EMD00853.1 - 0.015 15.0 4.6 0.017 14.8 3.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Snapin_Pallidin PF14712.1 EMD00853.1 - 0.018 15.3 4.0 0.027 14.7 2.8 1.3 1 0 0 1 1 1 0 Snapin/Pallidin NPV_P10 PF05531.7 EMD00853.1 - 0.13 12.5 1.5 0.24 11.6 1.0 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Spc42p PF11544.3 EMD00853.1 - 0.13 12.1 6.9 0.11 12.4 3.9 1.6 1 1 1 2 2 2 0 Spindle pole body component Spc42p Homeobox PF00046.24 EMD00854.1 - 1.3e-13 50.3 2.0 3.9e-13 48.7 1.4 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMD00854.1 - 0.04 13.6 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Rapamycin_bind PF08771.6 EMD00854.1 - 0.14 12.2 0.4 0.39 10.8 0.3 1.7 1 0 0 1 1 1 0 Rapamycin binding domain MerR-DNA-bind PF09278.6 EMD00854.1 - 0.17 12.3 0.2 0.48 10.8 0.1 1.7 1 0 0 1 1 1 0 MerR, DNA binding PLA2_B PF01735.13 EMD00856.1 - 7.6e-18 63.9 0.2 1.2e-08 33.6 0.0 2.4 2 1 0 2 2 2 2 Lysophospholipase catalytic domain HAD_2 PF13419.1 EMD00857.1 - 3.5e-13 50.1 0.0 5.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD00857.1 - 5.5e-08 32.4 0.2 1.2e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMD00857.1 - 7.6e-07 29.7 0.0 1.7e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_16 PF13191.1 EMD00858.1 - 9.9e-06 25.6 0.4 9.3e-05 22.4 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EMD00858.1 - 5.8e-05 22.5 0.1 0.00059 19.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EMD00858.1 - 0.0017 17.8 0.0 0.0059 16.1 0.0 1.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 EMD00858.1 - 0.0069 15.8 0.1 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EMD00858.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase DUF815 PF05673.8 EMD00858.1 - 0.028 13.3 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CLU PF13236.1 EMD00859.1 - 7.9e-80 267.4 0.0 1.7e-79 266.3 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EMD00859.1 - 1.2e-44 152.2 0.0 4e-44 150.5 0.0 2.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EMD00859.1 - 6.9e-26 90.2 0.3 1.6e-25 89.0 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EMD00859.1 - 1.7e-17 63.0 6.6 3.9e-08 33.1 0.0 3.9 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMD00859.1 - 4.4e-14 51.8 1.3 0.0019 18.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMD00859.1 - 0.00017 21.1 1.9 0.07 12.7 0.3 3.0 2 1 1 3 3 3 2 TPR repeat DUF727 PF05303.7 EMD00859.1 - 0.0031 17.2 0.0 0.0081 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.12 EMD00859.1 - 0.096 12.6 3.9 3.6 7.7 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 EMD00860.1 - 7.1e-19 68.3 0.0 1.2e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMD00860.1 - 6.9e-05 23.6 0.1 0.00035 21.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMD00860.1 - 9.1e-05 22.5 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD00860.1 - 0.00053 20.1 0.1 0.0025 17.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EMD00860.1 - 0.0085 15.8 0.1 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMD00860.1 - 0.015 14.3 0.1 0.04 12.9 0.1 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Zot PF05707.7 EMD00860.1 - 0.022 14.2 0.1 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_18 PF13238.1 EMD00860.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMD00860.1 - 0.043 13.5 0.2 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EMD00860.1 - 0.047 13.5 0.1 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMD00860.1 - 0.051 12.9 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EMD00860.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMD00860.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EMD00860.1 - 0.21 11.7 0.0 0.59 10.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EMD00860.1 - 0.22 11.0 0.1 0.43 10.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain OpcA_G6PD_assem PF10128.4 EMD00861.1 - 0.011 14.6 0.2 0.015 14.2 0.1 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit Env-gp36 PF09590.5 EMD00862.1 - 0.088 11.0 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein Abhydrolase_6 PF12697.2 EMD00863.1 - 8.9e-21 74.8 0.0 1.1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD00863.1 - 1.4e-13 50.9 0.0 2.5e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD00863.1 - 1.1e-10 41.3 0.0 2e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMD00863.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 EMD00863.1 - 0.00021 20.6 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EMD00863.1 - 0.00089 18.5 0.0 0.77 8.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.15 EMD00863.1 - 0.00092 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 EMD00863.1 - 0.0019 17.6 0.0 0.004 16.6 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 EMD00863.1 - 0.0056 16.5 0.3 0.23 11.3 0.1 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EMD00863.1 - 0.013 14.9 0.2 2.9 7.2 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EMD00863.1 - 0.04 13.4 0.0 0.06 12.9 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.7 EMD00863.1 - 0.043 13.5 0.0 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) Esterase_phd PF10503.4 EMD00863.1 - 0.11 11.7 0.0 5.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Fungal_trans PF04082.13 EMD00865.1 - 8.4e-32 110.0 0.0 1.6e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD00865.1 - 8.7e-10 38.3 12.3 1.5e-09 37.5 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP-alpha_N PF04086.8 EMD00865.1 - 3.6 6.8 6.2 5 6.4 0.4 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal FAP PF07174.6 EMD00866.1 - 4 6.6 11.0 4.1 6.6 7.7 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Beta_elim_lyase PF01212.16 EMD00868.1 - 1e-33 116.7 0.1 1.2e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMD00868.1 - 0.00063 18.8 0.1 0.0054 15.8 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ank_2 PF12796.2 EMD00869.1 - 1e-45 153.9 8.3 6.7e-17 61.6 0.5 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMD00869.1 - 1.2e-29 100.5 17.1 7e-09 35.0 0.1 6.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EMD00869.1 - 1.4e-26 92.3 11.4 1.4e-10 41.3 0.7 4.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD00869.1 - 1.5e-22 79.1 11.1 1.3e-08 34.7 0.4 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD00869.1 - 3.8e-21 73.0 11.1 7.4e-07 28.8 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Amidohydro_4 PF13147.1 EMD00876.1 - 8.9e-16 58.7 14.3 1.7e-14 54.5 3.4 3.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EMD00876.1 - 2.3e-08 34.0 0.4 1.1e-06 28.5 0.0 2.7 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMD00876.1 - 8.4e-07 28.7 0.4 5.6e-06 26.0 0.1 2.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD00876.1 - 1e-06 28.2 1.7 1.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family DUF4131 PF13567.1 EMD00876.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3650 PF12368.3 EMD00877.1 - 0.019 14.4 0.4 0.019 14.4 0.3 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3650) GST_N_3 PF13417.1 EMD00878.1 - 1.4e-16 60.4 0.0 4.4e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD00878.1 - 6.2e-13 48.5 0.0 1.5e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD00878.1 - 7.6e-08 32.4 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD00878.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EMD00878.1 - 0.00047 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.1 EMD00878.1 - 0.0081 16.6 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD00878.1 - 0.016 15.1 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M41 PF01434.13 EMD00879.1 - 1.8e-74 249.8 0.6 3.2e-74 248.9 0.0 1.8 3 0 0 3 3 3 1 Peptidase family M41 AAA PF00004.24 EMD00879.1 - 3.3e-42 143.8 0.0 7.7e-42 142.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EMD00879.1 - 9.7e-07 28.9 0.0 2.6e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EMD00879.1 - 0.00021 21.0 0.0 0.00069 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD00879.1 - 0.0003 20.9 0.1 0.23 11.5 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD00879.1 - 0.0025 18.6 0.0 0.0078 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMD00879.1 - 0.0069 15.1 0.1 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EMD00879.1 - 0.017 14.1 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMD00879.1 - 0.02 14.6 2.7 0.027 14.2 0.6 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 EMD00879.1 - 0.031 14.1 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMD00879.1 - 0.031 14.2 2.2 0.21 11.5 0.2 2.9 2 1 0 3 3 3 0 AAA ATPase domain AAA_2 PF07724.9 EMD00879.1 - 0.065 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EMD00879.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EMD00879.1 - 0.11 11.8 1.5 0.38 10.1 0.3 2.3 2 1 1 3 3 3 0 AAA domain Polyketide_cyc2 PF10604.4 EMD00880.1 - 1.2e-05 25.4 0.6 1.5e-05 25.2 0.4 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Amidohydro_4 PF13147.1 EMD00881.1 - 9.3e-26 91.4 0.6 2.5e-25 90.0 0.4 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMD00881.1 - 2.9e-15 56.7 0.2 1.3e-07 31.5 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMD00881.1 - 3.7e-14 52.2 1.7 1.3e-13 50.5 1.2 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD00881.1 - 2.9e-12 46.5 1.0 1.8e-07 30.7 0.0 3.2 2 1 1 3 3 3 3 Amidohydrolase family Urease_alpha PF00449.15 EMD00881.1 - 0.018 15.1 0.2 0.036 14.1 0.2 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain GST_C_3 PF14497.1 EMD00882.1 - 3.2e-10 40.3 0.0 6.4e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMD00882.1 - 0.00038 20.6 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD00882.1 - 0.024 14.5 0.0 0.059 13.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short PF00106.20 EMD00883.1 - 9.6e-26 90.6 0.1 1.4e-25 90.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD00883.1 - 1.4e-12 47.9 0.3 2.2e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD00883.1 - 4.9e-09 36.1 0.1 1.3e-08 34.7 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD00883.1 - 4.6e-05 23.5 0.0 0.00012 22.1 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMD00883.1 - 0.00068 18.8 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMD00883.1 - 0.0056 16.1 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.8 EMD00883.1 - 0.016 15.0 0.1 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Sds3 PF08598.6 EMD00884.1 - 1.4e-42 145.5 1.9 2.4e-42 144.8 1.3 1.4 1 0 0 1 1 1 1 Sds3-like Iron_permease PF04120.7 EMD00884.1 - 0.076 12.5 2.8 0.19 11.3 1.9 1.7 1 0 0 1 1 1 0 Low affinity iron permease DUF1053 PF06327.9 EMD00884.1 - 0.76 10.1 2.9 1.8 8.9 0.1 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) EPSP_synthase PF00275.15 EMD00886.1 - 4.9e-121 404.0 0.0 7.7e-121 403.4 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EMD00886.1 - 3.3e-98 327.7 0.0 5.5e-98 327.0 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EMD00886.1 - 4e-58 196.7 0.0 7.1e-58 195.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EMD00886.1 - 7.1e-36 123.4 0.0 8.5e-35 119.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EMD00886.1 - 7.5e-24 83.5 0.0 1.9e-23 82.2 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMD00886.1 - 1.1e-08 35.2 0.0 4.5e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EMD00886.1 - 1.5e-05 25.7 0.0 5.7e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Fe-ADH_2 PF13685.1 EMD00886.1 - 5.3e-05 22.6 0.0 0.00015 21.1 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase p450 PF00067.17 EMD00887.1 - 3.9e-61 207.0 0.0 4.9e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AIG2_2 PF13772.1 EMD00888.1 - 1.4e-06 28.3 0.0 2.6e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 AIG2-like family AIG2 PF06094.7 EMD00888.1 - 3.8e-05 24.1 0.0 5.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Rav1p_C PF12234.3 EMD00889.1 - 2.1e-103 346.6 0.0 6.8e-103 344.9 0.0 1.8 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EMD00889.1 - 1.5e-06 27.8 0.0 0.49 10.3 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat SGL PF08450.7 EMD00889.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region adh_short PF00106.20 EMD00890.1 - 1.2e-22 80.6 6.1 2.3e-22 79.6 4.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD00890.1 - 1e-13 51.6 1.6 7.3e-13 48.8 1.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD00890.1 - 4.1e-09 36.3 4.8 1.9e-08 34.2 3.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD00890.1 - 0.0002 20.8 0.3 0.00035 20.0 0.2 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD00890.1 - 0.086 11.5 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Tubulin PF00091.20 EMD00891.1 - 2e-70 236.9 0.0 3.8e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMD00891.1 - 2e-48 163.6 0.0 3.2e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMD00891.1 - 1.5e-05 25.0 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMD00891.1 - 0.0046 16.4 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CwfJ_C_1 PF04677.10 EMD00894.1 - 3.1e-27 94.6 0.0 4.8e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EMD00894.1 - 5.7e-23 81.2 0.1 1.7e-22 79.7 0.1 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.12 EMD00895.1 - 4.5e-70 235.8 0.0 7e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EMD00895.1 - 1.5e-05 24.5 0.0 0.002 17.5 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMD00895.1 - 7.1e-05 22.9 0.0 0.0002 21.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMD00895.1 - 0.00013 21.4 0.0 0.00024 20.6 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EMD00895.1 - 0.00036 19.3 0.1 0.029 13.1 0.1 2.2 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 EMD00895.1 - 0.00049 20.0 0.0 0.0018 18.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 EMD00895.1 - 0.00081 19.0 0.0 0.0019 17.8 0.0 1.6 2 0 0 2 2 1 1 NACHT domain AAA_17 PF13207.1 EMD00895.1 - 0.0013 19.5 0.3 0.01 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 EMD00895.1 - 0.0028 17.0 0.0 0.13 11.6 0.0 2.5 2 0 0 2 2 2 1 Ras family AAA_33 PF13671.1 EMD00895.1 - 0.0041 16.9 0.1 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD00895.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EMD00895.1 - 0.0068 16.8 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein G-alpha PF00503.15 EMD00895.1 - 0.0085 14.8 0.1 0.48 9.0 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.13 EMD00895.1 - 0.0097 15.1 0.1 0.24 10.6 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EMD00895.1 - 0.0098 15.3 0.1 0.079 12.4 0.0 2.5 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EMD00895.1 - 0.017 14.3 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.17 EMD00895.1 - 0.017 14.0 0.0 0.039 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EMD00895.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EMD00895.1 - 0.038 13.6 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EMD00895.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EMD00895.1 - 0.081 12.3 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.1 EMD00895.1 - 0.083 13.2 0.2 0.95 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 EMD00895.1 - 0.098 12.1 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EMD00895.1 - 0.12 12.5 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase F-box PF00646.28 EMD00896.1 - 0.043 13.4 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain Elongin_A PF06881.6 EMD00896.1 - 0.073 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A E1-E2_ATPase PF00122.15 EMD00897.1 - 1.3e-58 197.8 2.4 1.3e-58 197.8 1.7 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD00897.1 - 2.1e-49 167.5 6.8 2.1e-49 167.5 4.7 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD00897.1 - 2.6e-27 96.6 0.1 1e-26 94.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD00897.1 - 6.9e-20 70.7 0.0 1.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMD00897.1 - 1.9e-13 51.0 0.0 4.5e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD00897.1 - 1.8e-09 36.9 0.1 1.6e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD00897.1 - 0.00032 20.3 0.3 0.00054 19.6 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EMD00897.1 - 0.68 9.8 0.0 0.68 9.8 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) HD PF01966.17 EMD00898.1 - 5e-08 32.9 0.1 1.1e-07 31.8 0.1 1.6 1 1 1 2 2 2 1 HD domain DUF1998 PF09369.5 EMD00898.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1998) Phospho_p8 PF10195.4 EMD00899.1 - 0.14 12.0 0.0 2.3 8.1 0.0 2.0 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 14-3-3 PF00244.15 EMD00901.1 - 4.9e-09 35.6 0.0 8.9e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 14-3-3 protein Sod_Cu PF00080.15 EMD00902.1 - 1.9e-09 37.8 0.0 2.7e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Atrophin-1 PF03154.10 EMD00902.1 - 0.81 7.7 6.2 0.29 9.2 2.9 1.3 1 1 0 1 1 1 0 Atrophin-1 family HgmA PF04209.8 EMD00903.1 - 7e-184 611.1 0.0 8.1e-184 610.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 EMD00904.1 - 6.3e-46 156.5 0.0 8.4e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMD00904.1 - 1.4e-23 82.9 0.0 2.7e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.17 EMD00905.1 - 6.8e-59 199.5 0.0 7.8e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L2_C PF03947.13 EMD00906.1 - 1.3e-45 154.3 2.3 3.3e-45 153.0 1.6 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMD00906.1 - 1.7e-24 85.5 0.6 3.6e-24 84.5 0.4 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 EMD00907.1 - 9e-46 154.5 0.1 2.2e-44 150.0 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMD00907.1 - 6.8e-33 113.0 0.0 1.3e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Fungal_trans PF04082.13 EMD00908.1 - 1.9e-19 69.5 0.1 4.3e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD00908.1 - 6.6e-09 35.5 8.6 1.2e-08 34.6 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MASE1 PF05231.9 EMD00909.1 - 0.058 12.4 0.9 0.067 12.2 0.6 1.2 1 0 0 1 1 1 0 MASE1 Zn_clus PF00172.13 EMD00910.1 - 3.6e-08 33.1 10.7 5.6e-08 32.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EMD00911.1 - 7.1e-55 184.9 0.0 9.5e-55 184.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD00911.1 - 3.4e-15 55.6 0.0 4.2e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMD00911.1 - 4.2e-06 26.7 0.1 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase p450 PF00067.17 EMD00912.1 - 8.5e-63 212.4 0.0 1.1e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EMD00914.1 - 3.4e-51 169.3 18.4 1.4e-12 46.9 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EMD00914.1 - 1.1e-08 34.9 10.0 0.0054 16.4 0.2 3.8 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EMD00914.1 - 0.024 12.4 0.1 0.024 12.4 0.1 1.9 2 0 0 2 2 2 0 IKI3 family Nucleoporin_N PF08801.6 EMD00914.1 - 1.9 7.1 6.9 5.5 5.6 0.5 3.1 2 2 0 2 2 2 0 Nup133 N terminal like Nefa_Nip30_N PF10187.4 EMD00916.1 - 3.4e-30 104.2 5.9 7.1e-30 103.1 4.1 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 UVR PF02151.14 EMD00916.1 - 0.0072 15.8 1.9 0.0072 15.8 1.3 2.2 2 0 0 2 2 2 1 UvrB/uvrC motif YkyA PF10368.4 EMD00916.1 - 0.0088 15.4 5.6 0.012 14.9 3.9 1.2 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein DUF2075 PF09848.4 EMD00916.1 - 0.0096 14.9 1.1 0.012 14.5 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF2265 PF10023.4 EMD00916.1 - 0.21 10.6 3.1 0.3 10.2 2.2 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) AUX_IAA PF02309.11 EMD00916.1 - 0.41 10.3 5.7 0.51 10.0 4.0 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF883 PF05957.8 EMD00916.1 - 0.8 10.1 9.5 0.21 11.9 2.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Aldo_ket_red PF00248.16 EMD00917.1 - 1.7e-53 181.2 0.0 2e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NHL PF01436.16 EMD00918.1 - 0.022 14.6 0.0 22 5.2 0.0 3.7 3 0 0 3 3 3 0 NHL repeat GxDLY PF14607.1 EMD00918.1 - 0.046 13.1 0.3 0.41 10.1 0.1 2.2 2 0 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type AdoHcyase PF05221.12 EMD00919.1 - 1.6e-130 433.8 0.0 1.5e-129 430.6 0.0 1.9 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EMD00919.1 - 5.3e-84 279.9 2.1 8.9e-84 279.2 1.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMD00919.1 - 1.1e-07 31.1 0.1 2.4e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EMD00919.1 - 0.0017 17.7 0.2 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EMD00919.1 - 0.0036 17.2 0.0 0.0095 15.9 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EMD00919.1 - 0.0094 15.5 0.1 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4448 PF14610.1 EMD00919.1 - 0.042 13.3 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ABC_tran PF00005.22 EMD00921.1 - 4e-47 159.9 1.7 5.3e-22 78.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EMD00921.1 - 4e-20 71.4 5.5 4e-20 71.4 3.8 3.1 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EMD00921.1 - 1.2e-12 48.4 6.1 0.0058 16.6 0.1 4.7 3 2 1 4 4 3 3 AAA domain SMC_N PF02463.14 EMD00921.1 - 5.9e-09 35.4 1.2 0.082 12.1 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMD00921.1 - 2.1e-07 31.7 0.3 0.047 14.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EMD00921.1 - 9.4e-06 25.0 0.4 0.072 12.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMD00921.1 - 2.5e-05 23.5 0.1 0.021 14.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMD00921.1 - 3.2e-05 24.2 2.7 0.22 11.8 0.0 4.0 4 1 0 4 4 3 2 AAA domain Miro PF08477.8 EMD00921.1 - 3.3e-05 24.3 0.3 0.059 13.8 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein MMR_HSR1 PF01926.18 EMD00921.1 - 3.8e-05 23.6 0.0 0.012 15.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMD00921.1 - 6.5e-05 23.0 0.6 0.83 9.8 0.0 3.4 3 1 0 3 3 2 2 AAA domain NACHT PF05729.7 EMD00921.1 - 0.00045 19.9 0.1 0.59 9.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 EMD00921.1 - 0.00054 19.8 0.1 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EMD00921.1 - 0.00056 19.9 3.6 0.037 13.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EMD00921.1 - 0.0011 18.5 0.5 1.8 7.9 0.0 3.7 4 0 0 4 4 4 1 AAA-like domain AAA_23 PF13476.1 EMD00921.1 - 0.0012 19.1 21.1 0.033 14.5 0.0 4.9 5 0 0 5 5 5 2 AAA domain AAA_15 PF13175.1 EMD00921.1 - 0.0013 17.9 6.8 0.2 10.6 0.1 4.2 4 2 0 4 4 4 1 AAA ATPase domain AAA_16 PF13191.1 EMD00921.1 - 0.0013 18.7 2.9 0.094 12.6 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain MobB PF03205.9 EMD00921.1 - 0.0013 18.4 0.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EMD00921.1 - 0.0019 18.4 0.1 2 8.6 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EMD00921.1 - 0.0048 16.0 0.1 0.53 9.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EMD00921.1 - 0.0053 16.9 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EMD00921.1 - 0.0053 16.6 0.0 5.4 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMD00921.1 - 0.0068 16.3 0.2 12 5.8 0.0 3.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EMD00921.1 - 0.007 15.1 5.5 0.71 8.5 0.0 3.0 3 0 0 3 3 3 2 ArgK protein NTPase_1 PF03266.10 EMD00921.1 - 0.011 15.4 0.1 2 8.1 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 EMD00921.1 - 0.015 14.7 0.0 7 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMD00921.1 - 0.031 13.8 0.1 10 5.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EMD00921.1 - 0.032 13.1 0.2 1.5 7.6 0.0 2.7 3 1 0 3 3 3 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EMD00921.1 - 0.034 13.6 0.1 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EMD00921.1 - 0.035 13.5 0.6 5.6 6.3 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EMD00921.1 - 0.048 12.5 0.0 2.9 6.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 EMD00921.1 - 0.058 13.1 0.3 7.7 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EMD00921.1 - 0.058 12.8 0.1 3.3 7.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EMD00921.1 - 0.12 12.1 5.6 1.2 8.9 0.0 3.8 4 0 0 4 4 4 0 Dynamin family PduV-EutP PF10662.4 EMD00921.1 - 0.16 11.4 1.2 5.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation YchF-GTPase_C PF06071.8 EMD00922.1 - 5e-32 109.5 0.3 1.1e-31 108.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EMD00922.1 - 9.4e-11 41.6 0.0 2.2e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD00922.1 - 0.0035 16.6 0.0 0.0082 15.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EMD00922.1 - 0.012 15.4 0.1 0.046 13.5 0.0 2.1 3 0 0 3 3 3 0 TGS domain SecA_PP_bind PF01043.15 EMD00922.1 - 0.056 13.8 0.1 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Ank_5 PF13857.1 EMD00923.1 - 1e-17 63.7 1.4 8.1e-09 35.4 0.0 5.7 5 1 1 6 6 6 2 Ankyrin repeats (many copies) VPS9 PF02204.13 EMD00923.1 - 1.7e-14 53.6 0.0 3.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EMD00923.1 - 4.3e-13 49.4 0.4 7.8e-05 22.9 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMD00923.1 - 2.2e-08 33.4 0.7 0.37 10.7 0.0 5.7 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EMD00923.1 - 2.3e-08 33.5 0.1 0.61 10.5 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EMD00923.1 - 9.3e-07 29.2 0.8 0.61 10.6 0.0 4.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) PX PF00787.19 EMD00923.1 - 0.026 14.3 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 PX domain HD PF01966.17 EMD00925.1 - 4.6e-07 29.8 2.5 9.9e-06 25.5 0.8 2.3 2 0 0 2 2 2 1 HD domain OmdA PF13376.1 EMD00925.1 - 0.039 13.6 0.9 0.039 13.6 0.6 1.9 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Ribosomal_S11 PF00411.14 EMD00926.1 - 0.00065 19.8 0.1 0.0017 18.5 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.10 EMD00927.1 - 1.1e-32 112.9 0.0 2.7e-32 111.7 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain MSA-2c PF12238.3 EMD00927.1 - 3.1 7.4 5.9 4.9 6.7 3.3 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c CHCH PF06747.8 EMD00928.1 - 2.9e-08 33.4 2.2 4.2e-08 32.9 1.5 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EMD00928.1 - 0.0019 18.1 3.4 0.012 15.6 2.4 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 EMD00928.1 - 0.075 12.9 2.4 5.6 6.9 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EMD00928.1 - 0.12 12.2 2.4 1.4 8.7 1.8 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EMD00928.1 - 0.14 12.1 4.8 0.62 10.1 0.2 2.6 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) HLH PF00010.21 EMD00929.1 - 7.9e-12 44.6 0.0 2.7e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 EMD00930.1 - 1.6e-32 112.1 13.5 2e-32 111.7 9.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3112 PF11309.3 EMD00930.1 - 0.025 14.3 4.0 0.034 13.9 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Peptidase_M50 PF02163.17 EMD00930.1 - 0.036 13.0 0.0 0.059 12.3 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M50 DUF2632 PF10943.3 EMD00930.1 - 0.7 9.3 8.9 0.98 8.8 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) CFEM PF05730.6 EMD00931.1 - 3.6e-09 36.3 9.5 7.5e-09 35.2 6.6 1.6 1 0 0 1 1 1 1 CFEM domain DUF3487 PF11990.3 EMD00931.1 - 0.15 11.4 1.9 0.92 8.9 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3487) Vac_ImportDeg PF09783.4 EMD00932.1 - 6.5e-69 230.9 0.2 8e-69 230.6 0.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mito_carr PF00153.22 EMD00933.1 - 2.3e-46 155.4 0.1 1.1e-16 60.2 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein SLD3 PF08639.5 EMD00935.1 - 4.1e-85 286.3 10.1 5.7e-85 285.8 7.0 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 DUF1675 PF07897.6 EMD00935.1 - 0.083 12.7 5.6 0.23 11.2 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MFS_1 PF07690.11 EMD00938.1 - 6e-42 143.6 39.5 4.1e-41 140.8 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD00938.1 - 1.3e-14 53.6 27.5 2.3e-14 52.8 19.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMD00938.1 - 7.5e-10 37.6 0.9 1.3e-09 36.8 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAP2 PF01569.16 EMD00938.1 - 0.01 15.4 6.0 0.01 15.4 4.2 3.2 3 1 0 3 3 3 0 PAP2 superfamily Pox_Ag35 PF03286.9 EMD00938.1 - 4.6 6.7 9.2 6.9 6.1 6.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Complex1_LYR PF05347.10 EMD00939.1 - 9.8e-09 34.8 1.7 9.8e-09 34.8 1.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD00939.1 - 0.00026 21.1 6.1 0.00042 20.4 4.2 1.7 1 1 0 1 1 1 1 Complex1_LYR-like GSP_synth PF03738.9 EMD00939.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp PEMT PF04191.8 EMD00940.1 - 5.6e-34 116.4 1.4 5.6e-34 116.4 1.0 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Aa_trans PF01490.13 EMD00941.1 - 4.1e-26 91.3 34.2 4.8e-26 91.1 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein S1FA PF04689.8 EMD00941.1 - 1.3 8.9 3.3 0.94 9.4 0.3 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA DsbD_2 PF13386.1 EMD00942.1 - 0.06 13.0 0.2 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region API5 PF05918.6 EMD00943.1 - 0.6 8.5 3.7 0.8 8.1 2.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gly_rich PF12810.2 EMD00943.1 - 0.66 9.5 7.8 0.97 8.9 5.4 1.2 1 0 0 1 1 1 0 Glycine rich protein MFS_1 PF07690.11 EMD00944.1 - 1.8e-36 125.5 37.4 1.8e-36 125.5 25.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EMD00945.1 - 6.1e-28 97.5 57.8 4e-25 88.2 22.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD00945.1 - 4.3e-18 65.1 23.2 1.2e-17 63.6 16.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EMD00945.1 - 0.0054 16.4 0.4 0.11 12.2 0.0 3.0 3 0 0 3 3 3 1 MFS_1 like family HLH PF00010.21 EMD00946.1 - 1.3e-14 53.6 0.4 2.2e-14 52.8 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tombus_movement PF05318.7 EMD00946.1 - 4.6 7.9 5.9 1.8 9.2 1.4 2.2 2 0 0 2 2 2 0 Tombusvirus movement protein HCO3_cotransp PF00955.16 EMD00948.1 - 5e-53 180.5 11.3 4.1e-32 111.5 1.9 2.5 1 1 1 2 2 2 2 HCO3- transporter family Gate PF07670.9 EMD00948.1 - 0.6 10.0 5.7 3.6 7.5 0.8 3.4 2 1 0 2 2 2 0 Nucleoside recognition Alliinase_C PF04864.8 EMD00949.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Allinase SUZ PF12752.2 EMD00950.1 - 6.3e-05 23.4 5.7 6.3e-05 23.4 4.0 3.5 2 1 1 3 3 3 1 SUZ domain SUZ-C PF12901.2 EMD00950.1 - 0.027 14.1 3.8 0.027 14.1 2.7 2.0 2 0 0 2 2 2 0 SUZ-C motif DUF1682 PF07946.9 EMD00950.1 - 9.4 4.9 9.4 15 4.3 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PXA PF02194.10 EMD00952.1 - 3.3e-45 153.9 0.6 4.9e-44 150.1 0.0 3.0 4 0 0 4 4 4 1 PXA domain Nexin_C PF08628.7 EMD00952.1 - 5.1e-27 94.1 2.0 1.2e-26 93.0 0.0 2.8 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EMD00952.1 - 1.8e-21 76.0 0.3 3.8e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EMD00952.1 - 4.2e-10 39.7 0.0 2e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain tRNA-synt_2b PF00587.20 EMD00953.1 - 6.8e-36 123.4 0.0 9.9e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMD00953.1 - 1.4e-13 50.5 0.0 2.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 EMD00954.1 - 2.5e-47 160.3 0.0 6.1e-47 159.1 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Nop14 PF04147.7 EMD00954.1 - 9.2 4.0 16.2 18 3.1 11.3 1.4 1 0 0 1 1 1 0 Nop14-like family Rox3 PF08633.5 EMD00955.1 - 1.6e-24 87.2 0.4 6.7e-24 85.2 0.0 2.0 2 0 0 2 2 2 1 Rox3 mediator complex subunit Cut8_N PF14482.1 EMD00955.1 - 1.3 9.0 5.5 2.1 8.4 0.2 3.3 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Na_H_Exchanger PF00999.16 EMD00956.1 - 1.6e-28 99.3 37.6 1.4e-23 83.1 16.2 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Rad10 PF03834.9 EMD00957.1 - 5.8e-31 105.9 0.0 8.9e-31 105.4 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EMD00957.1 - 4.2e-05 23.6 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain PfUIS3 PF11567.3 EMD00957.1 - 0.077 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein HHH_2 PF12826.2 EMD00957.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Zn_clus PF00172.13 EMD00958.1 - 2.4e-11 43.3 7.9 2.4e-11 43.3 5.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.7 EMD00959.1 - 2.5e-100 335.5 5.1 3.3e-100 335.1 3.6 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EMD00959.1 - 4.7e-31 105.5 8.8 6.7e-13 47.9 0.3 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EMD00959.1 - 0.017 14.7 0.0 0.27 10.9 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Fungal_trans PF04082.13 EMD00960.1 - 1.3e-17 63.5 0.1 2.1e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EMD00961.1 - 9.4e-20 70.5 0.2 1.5e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD00961.1 - 3.3e-06 26.9 2.4 5.4e-06 26.2 1.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EMD00962.1 - 6.8e-33 113.9 3.7 9.6e-33 113.4 2.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD00962.1 - 3.7e-22 77.5 0.7 6.4e-22 76.8 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMD00962.1 - 7.7e-11 42.5 0.1 3e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD00962.1 - 3.4e-08 33.7 1.6 5.2e-08 33.2 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Trs65 PF12735.2 EMD00963.1 - 4.9e-13 49.0 0.0 1e-12 48.0 0.0 1.5 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 UQ_con PF00179.21 EMD00964.1 - 1.7e-19 69.6 0.0 1.8e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMD00964.1 - 0.024 14.5 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain 4HBT PF03061.17 EMD00965.1 - 5.8e-08 32.7 0.0 9.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_hydro_6 PF01341.12 EMD00967.1 - 4.1e-107 358.0 1.0 5.2e-107 357.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EMD00967.1 - 1.2e-06 28.0 16.2 3.6e-06 26.5 11.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain SnoaL_4 PF13577.1 EMD00968.1 - 6.2e-18 64.9 0.0 7.8e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ecl1 PF12855.2 EMD00969.1 - 0.00024 20.3 0.6 0.0005 19.3 0.4 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF2256 PF10013.4 EMD00969.1 - 0.021 14.5 4.2 0.021 14.5 2.9 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.13 EMD00969.1 - 0.18 11.7 2.9 0.38 10.6 2.0 1.5 1 0 0 1 1 1 0 MYND finger Metallophos PF00149.23 EMD00970.1 - 4.5e-06 26.2 1.0 4.5e-06 26.2 0.7 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase HET PF06985.6 EMD00971.1 - 3e-23 82.4 0.1 4.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PGK PF00162.14 EMD00972.1 - 6.7e-153 508.7 0.1 7.6e-153 508.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Acetyltransf_CG PF14542.1 EMD00972.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Aminotran_4 PF01063.14 EMD00974.1 - 6.8e-22 78.0 0.0 9.4e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV p450 PF00067.17 EMD00975.1 - 1.6e-72 244.5 0.0 2.1e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EMD00975.1 - 1.5e-36 125.8 0.0 2.7e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMD00975.1 - 1.2e-23 83.6 0.4 2.4e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EMD00975.1 - 6.1e-15 55.7 0.0 2e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMD00975.1 - 0.00078 19.3 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Flavodoxin_5 PF12724.2 EMD00975.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EMD00975.1 - 0.0019 18.0 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 NrdI Flavodoxin like SIS_2 PF13580.1 EMD00975.1 - 0.15 11.7 0.2 42 3.8 0.0 3.6 2 1 1 3 3 3 0 SIS domain Mpv17_PMP22 PF04117.7 EMD00976.1 - 5.6e-20 70.7 0.3 5.6e-20 70.7 0.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Asn_synthase PF00733.16 EMD00977.1 - 9.7e-53 179.2 0.0 1.2e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase Pro_CA PF00484.14 EMD00978.1 - 8.8e-20 71.2 1.2 1.6e-19 70.3 0.8 1.4 1 1 0 1 1 1 1 Carbonic anhydrase Glutaredoxin PF00462.19 EMD00979.1 - 5.9e-15 55.0 0.0 1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.15 EMD00979.1 - 0.026 14.1 0.1 2.3 7.7 0.0 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Ribosomal_L6 PF00347.18 EMD00980.1 - 1.3e-26 92.9 3.4 2.3e-12 47.2 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DAG1 PF05454.6 EMD00981.1 - 0.071 12.2 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) LSM PF01423.17 EMD00983.1 - 1.6e-16 59.5 0.2 2.5e-16 58.9 0.1 1.4 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 EMD00983.1 - 0.037 13.9 0.1 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin6 PF06372.7 EMD00983.1 - 0.085 12.1 0.1 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Gemin6 protein FF PF01846.14 EMD00984.1 - 2e-37 126.8 10.3 3.2e-10 39.8 1.1 6.1 6 0 0 6 6 6 4 FF domain WW PF00397.21 EMD00984.1 - 0.072 12.9 14.0 0.15 11.9 1.1 3.6 3 0 0 3 3 3 0 WW domain PrkA PF06798.7 EMD00985.1 - 0.037 13.3 1.1 0.044 13.0 0.8 1.1 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain eIF3_p135 PF12807.2 EMD00985.1 - 0.081 12.8 0.3 0.098 12.5 0.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 ABC_tran PF00005.22 EMD00986.1 - 4.9e-24 85.1 0.0 1.1e-15 58.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD00986.1 - 2.8e-10 39.7 1.0 0.0021 17.2 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD00986.1 - 1.8e-09 37.9 2.5 0.046 13.6 0.0 3.7 4 1 1 5 5 5 3 AAA domain AAA_15 PF13175.1 EMD00986.1 - 5.2e-05 22.4 0.0 2.5 7.0 0.0 3.5 3 1 1 4 4 4 2 AAA ATPase domain AAA_13 PF13166.1 EMD00986.1 - 0.00092 17.8 0.1 0.0019 16.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMD00986.1 - 0.0028 17.8 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EMD00986.1 - 0.0044 16.6 0.0 0.0095 15.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EMD00986.1 - 0.0052 16.9 0.2 0.02 15.0 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EMD00986.1 - 0.0075 16.7 0.1 0.035 14.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EMD00986.1 - 0.0087 15.5 0.1 0.025 14.0 0.1 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EMD00986.1 - 0.018 15.8 0.1 0.097 13.4 0.0 2.4 2 2 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EMD00986.1 - 0.019 15.3 0.1 0.04 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMD00986.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMD00986.1 - 0.039 13.4 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EMD00986.1 - 0.049 13.5 0.1 8.2 6.4 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EMD00986.1 - 0.049 13.8 0.0 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 EMD00986.1 - 0.051 12.7 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EMD00986.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EMD00986.1 - 0.087 11.9 0.2 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EMD00986.1 - 0.11 12.0 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SNF2_N PF00176.18 EMD00989.1 - 2.6e-65 220.1 0.0 4.1e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EMD00989.1 - 4.5e-17 61.4 8.3 7.7e-14 51.1 1.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EMD00989.1 - 1.2e-13 50.7 0.0 4.9e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 EMD00989.1 - 8e-10 38.8 0.0 2.7e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) DNA_pol3_a_NII PF11490.3 EMD00989.1 - 0.05 13.2 4.5 0.1 12.2 2.3 2.1 1 1 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF3808 PF10300.4 EMD00990.1 - 4.1e-133 444.3 0.0 5.1e-133 444.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EMD00990.1 - 0.19 11.3 4.4 0.51 10.0 0.9 3.0 3 0 0 3 3 3 0 TPR repeat TruB_C PF09142.6 EMD00991.1 - 5.5e-07 29.1 0.2 0.033 13.8 0.0 3.6 3 0 0 3 3 3 2 tRNA Pseudouridine synthase II, C terminal F-box-like PF12937.2 EMD00991.1 - 1e-05 25.1 0.3 2.3e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD00991.1 - 0.00021 20.8 0.0 0.00052 19.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain PD40 PF07676.7 EMD00991.1 - 0.12 12.0 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CIA30 PF08547.7 EMD00992.1 - 7.9e-37 126.5 0.0 9.9e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EMD00992.1 - 0.056 13.1 0.0 0.15 11.7 0.0 1.9 1 1 0 1 1 1 0 Carbohydrate binding domain (family 11) bZIP_1 PF00170.16 EMD00993.1 - 7.5e-07 29.0 6.1 1.3e-06 28.2 4.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD00993.1 - 1.6e-05 24.6 7.2 2.4e-05 24.0 5.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD00993.1 - 0.006 16.8 6.2 0.01 16.0 4.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Leu_zip PF15294.1 EMD00993.1 - 0.032 13.3 0.5 0.045 12.8 0.3 1.1 1 0 0 1 1 1 0 Leucine zipper Dynactin_p22 PF07426.6 EMD00993.1 - 0.066 12.4 0.3 0.13 11.5 0.1 1.4 2 0 0 2 2 2 0 Dynactin subunit p22 SR-25 PF10500.4 EMD00993.1 - 0.096 12.1 7.1 0.16 11.4 4.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PT PF04886.7 EMD00994.1 - 0.25 10.6 2.9 0.36 10.1 2.0 1.2 1 0 0 1 1 1 0 PT repeat Prim_Zn_Ribbon PF08273.7 EMD00995.1 - 0.02 14.9 0.5 0.032 14.2 0.4 1.3 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Zn_Tnp_IS1595 PF12760.2 EMD00995.1 - 0.022 14.5 0.3 0.036 13.8 0.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Methyltransf_11 PF08241.7 EMD00997.1 - 2.3e-17 63.2 0.0 7.1e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD00997.1 - 3.9e-14 52.4 0.0 6.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD00997.1 - 3.3e-12 46.4 0.0 5.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD00997.1 - 4.4e-10 39.9 0.0 8.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD00997.1 - 1.6e-09 38.0 0.1 5e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD00997.1 - 3.9e-08 33.8 0.0 7.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD00997.1 - 1.8e-06 27.2 0.0 2.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMD00997.1 - 1.1e-05 25.3 0.0 2.9e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD00997.1 - 2.9e-05 23.5 0.0 4.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EMD00997.1 - 2.9e-05 23.2 0.0 4.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EMD00997.1 - 0.00035 19.7 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EMD00997.1 - 0.0014 17.8 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EMD00997.1 - 0.0082 15.8 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMD00997.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FmrO PF07091.6 EMD00997.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 EMD00997.1 - 0.059 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 EMD00997.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_2 PF00891.13 EMD00997.1 - 0.089 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 EMD00997.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DAO PF01266.19 EMD00998.1 - 7.9e-44 150.0 0.8 9.2e-44 149.7 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD00998.1 - 4.2e-05 23.4 0.2 0.00013 21.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMD00998.1 - 0.00059 19.9 0.3 0.086 12.8 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD00998.1 - 0.0025 16.7 0.2 0.024 13.4 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 EMD00998.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EMD00998.1 - 0.02 13.9 0.1 0.041 12.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family LIP PF03583.9 EMD00999.1 - 0.0069 15.6 0.0 0.028 13.6 0.1 2.0 2 0 0 2 2 2 1 Secretory lipase EHN PF06441.7 EMD01000.1 - 7.1e-33 112.8 0.1 1e-31 109.1 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMD01000.1 - 1.1e-09 38.5 0.8 1.1e-09 38.5 0.6 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD01000.1 - 5.4e-06 26.1 0.0 1.5e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Granulin PF00396.13 EMD01001.1 - 7.6 6.7 12.3 53 4.0 8.5 2.2 1 1 0 1 1 1 0 Granulin Aldo_ket_red PF00248.16 EMD01002.1 - 3.6e-66 222.8 0.0 4.5e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 EMD01004.1 - 5e-16 58.6 0.0 1.2e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD01004.1 - 5.5e-08 32.1 0.0 2.1e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Sas10 PF09368.5 EMD01006.1 - 1.9e-29 101.6 9.9 6.2e-29 99.9 5.1 2.6 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EMD01006.1 - 5.4e-14 52.1 1.5 1.1e-13 51.1 0.1 2.3 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Alpha-amylase PF00128.19 EMD01007.1 - 1.2e-90 304.1 0.3 1.9e-90 303.4 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EMD01007.1 - 0.00011 21.2 0.1 0.00037 19.5 0.0 1.8 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme NAD_binding_4 PF07993.7 EMD01008.1 - 2.6e-43 147.7 0.0 1.6e-41 141.9 0.0 2.5 3 0 0 3 3 3 1 Male sterility protein AMP-binding PF00501.23 EMD01008.1 - 1.5e-24 86.2 0.0 5.8e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EMD01008.1 - 6.2e-13 48.7 0.0 1.5e-12 47.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMD01008.1 - 3.5e-06 27.1 0.2 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EMD01008.1 - 0.0051 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMD01008.1 - 0.12 12.3 0.0 11 5.9 0.0 2.9 2 0 0 2 2 2 0 NADH(P)-binding RmlD_sub_bind PF04321.12 EMD01008.1 - 0.13 11.1 0.1 6.9 5.4 0.0 2.9 2 1 0 2 2 2 0 RmlD substrate binding domain Acyl-CoA_dh_1 PF00441.19 EMD01009.1 - 1.5e-27 96.5 2.8 2.3e-27 95.9 1.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD01009.1 - 2.3e-21 75.0 0.5 5.2e-21 73.8 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMD01009.1 - 1.6e-19 70.5 0.1 4.6e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD01009.1 - 0.0003 21.0 1.5 0.00049 20.3 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain IBR PF01485.16 EMD01010.1 - 2.5e-10 40.0 14.8 2.5e-10 40.0 3.2 3.1 3 0 0 3 3 3 2 IBR domain Pkinase PF00069.20 EMD01011.1 - 2e-67 227.0 0.0 3.4e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD01011.1 - 7.4e-38 130.0 0.0 1.2e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD01011.1 - 2.1e-06 26.9 0.0 4.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD01011.1 - 0.00021 21.1 0.0 0.00056 19.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMD01011.1 - 0.0017 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EMD01011.1 - 0.073 12.4 0.1 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Fungal_trans_2 PF11951.3 EMD01012.1 - 8e-18 64.1 0.3 3.8e-17 61.9 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD01012.1 - 0.0042 16.9 1.1 0.0081 16.0 0.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMD01013.1 - 4.6e-29 101.4 0.0 5.3e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD01013.1 - 7e-25 88.1 0.0 9.1e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD01013.1 - 1.6e-11 44.1 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD01013.1 - 8.3e-07 28.6 0.1 1e-06 28.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EMD01013.1 - 0.0002 20.4 0.1 0.00028 20.0 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EMD01013.1 - 0.00028 20.8 0.1 0.00047 20.1 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EMD01013.1 - 0.001 18.7 0.2 0.0014 18.3 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EMD01013.1 - 0.0024 17.7 0.9 0.0042 16.9 0.6 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 EMD01013.1 - 0.007 16.7 0.1 0.013 15.9 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EMD01013.1 - 0.021 13.7 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMD01013.1 - 0.035 14.1 0.2 0.083 12.8 0.1 1.3 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EMD01013.1 - 0.047 12.8 0.2 0.074 12.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMD01013.1 - 0.065 11.9 0.5 0.12 11.0 0.4 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.16 EMD01013.1 - 0.069 12.7 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.20 EMD01013.1 - 0.072 12.3 0.1 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Dak1 PF02733.12 EMD01014.1 - 6.8e-109 363.3 0.0 9.4e-109 362.9 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EMD01014.1 - 9.4e-34 116.5 3.2 9.4e-34 116.5 2.2 1.7 2 0 0 2 2 2 1 DAK2 domain F_bP_aldolase PF01116.15 EMD01015.1 - 3.9e-78 262.4 0.0 4.4e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UPF0728 PF15092.1 EMD01015.1 - 0.023 14.5 0.1 0.068 13.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 adh_short PF00106.20 EMD01016.1 - 2.7e-26 92.4 0.4 3.3e-26 92.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD01016.1 - 1.7e-24 86.9 0.1 2.3e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD01016.1 - 3.7e-12 46.2 0.1 5.5e-12 45.7 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD01016.1 - 0.00047 19.6 0.0 0.00063 19.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMD01016.1 - 0.0015 17.5 0.1 0.0018 17.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMD01016.1 - 0.0085 14.8 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EMD01017.1 - 1.1e-37 129.6 29.1 1.1e-37 129.6 20.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Ammonium_transp PF00909.16 EMD01019.1 - 1.7e-119 398.8 31.7 1.9e-119 398.6 22.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RRM_1 PF00076.17 EMD01021.1 - 1e-08 34.6 0.3 0.0013 18.3 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD01021.1 - 1.9e-07 30.9 0.1 0.025 14.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD01021.1 - 0.00043 20.0 0.0 0.0026 17.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.16 EMD01022.1 - 5.8e-57 192.6 0.0 6.5e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.1 EMD01023.1 - 1.1e-10 41.2 7.8 1e-07 31.8 0.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD01023.1 - 5.5e-07 29.4 8.2 0.00025 21.1 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD01023.1 - 2.9e-06 27.2 10.0 2.8e-05 24.1 0.1 4.2 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMD01023.1 - 0.3 11.2 4.7 2.8 8.1 0.3 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMD01023.1 - 0.88 9.7 5.1 4.7 7.4 0.9 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3899 PF13038.1 EMD01024.1 - 0.11 12.6 0.3 0.11 12.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) COX4_pro PF03626.9 EMD01024.1 - 0.16 12.0 3.3 0.28 11.2 2.3 1.4 1 1 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV DUF202 PF02656.10 EMD01024.1 - 4.7 7.5 5.9 25 5.1 4.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Nup160 PF11715.3 EMD01025.1 - 2e-67 227.6 0.8 3e-67 227.0 0.5 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 NPR3 PF03666.8 EMD01026.1 - 3.3e-85 286.3 0.1 8.3e-49 166.3 0.7 2.1 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 HTH_28 PF13518.1 EMD01026.1 - 0.046 13.7 0.3 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Mem_trans PF03547.13 EMD01028.1 - 8e-24 83.6 4.9 3.5e-23 81.5 3.4 1.7 1 1 0 1 1 1 1 Membrane transport protein DUF4396 PF14342.1 EMD01028.1 - 0.88 9.6 7.9 0.061 13.4 0.9 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4396) K_trans PF02705.11 EMD01029.1 - 8.8e-185 615.0 15.4 1.2e-184 614.6 10.7 1.2 1 0 0 1 1 1 1 K+ potassium transporter HAD_2 PF13419.1 EMD01030.1 - 5.7e-28 98.3 0.1 7.1e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GRP PF07172.6 EMD01033.1 - 0.0017 18.8 1.4 0.0022 18.4 1.0 1.2 1 0 0 1 1 1 1 Glycine rich protein family Mito_carr PF00153.22 EMD01034.1 - 1.6e-68 226.4 0.5 1e-23 82.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Prp31_C PF09785.4 EMD01035.1 - 3.4e-44 150.2 1.4 6.2e-44 149.3 1.0 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EMD01035.1 - 1e-38 131.9 0.3 1.8e-38 131.1 0.2 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMD01035.1 - 2.9e-21 75.0 0.0 2e-20 72.3 0.0 2.3 3 0 0 3 3 3 1 NOSIC (NUC001) domain MIP-T3 PF10243.4 EMD01036.1 - 4.3 5.6 15.3 4.6 5.6 10.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DEAD PF00270.24 EMD01037.1 - 2.7e-45 153.8 0.0 5e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD01037.1 - 2.6e-23 81.6 0.0 5.5e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD01037.1 - 2.6e-05 24.1 0.3 0.0013 18.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMD01037.1 - 3.1e-05 22.9 0.0 4.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1180 PF06679.7 EMD01039.1 - 6.9e-05 22.7 0.0 6.9e-05 22.7 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1180) gpUL132 PF11359.3 EMD01039.1 - 0.0081 15.5 0.3 0.0081 15.5 0.2 1.9 2 0 0 2 2 2 1 Glycoprotein UL132 Kelch_1 PF01344.20 EMD01039.1 - 0.023 14.2 1.5 4.9 6.7 0.1 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 EMD01039.1 - 0.032 14.4 1.0 5.7 7.2 0.0 3.9 4 0 0 4 4 4 0 Kelch motif adh_short PF00106.20 EMD01040.1 - 1.3e-35 122.7 1.0 1.7e-35 122.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD01040.1 - 1.3e-33 116.7 0.1 1.6e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD01040.1 - 1.5e-20 73.6 0.4 2.2e-20 73.0 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD01040.1 - 2.3e-08 33.7 1.0 7.1e-08 32.1 0.7 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMD01040.1 - 1.2e-06 27.7 0.6 1.5e-06 27.3 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EMD01040.1 - 0.0012 19.1 0.1 0.0029 17.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EMD01040.1 - 0.0067 15.1 0.3 0.0089 14.7 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 EMD01040.1 - 0.023 14.3 0.0 0.034 13.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EMD01040.1 - 0.026 13.7 0.1 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 EMD01040.1 - 0.035 13.8 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EMD01040.1 - 0.046 13.4 0.2 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_25 PF13649.1 EMD01040.1 - 0.051 13.9 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EMD01040.1 - 0.067 13.2 0.4 0.15 12.1 0.3 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EMD01040.1 - 0.081 11.8 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DUF1776 PF08643.5 EMD01040.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.17 EMD01041.1 - 3.7e-21 75.1 0.0 4.1e-19 68.4 0.0 2.8 2 1 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.11 EMD01042.1 - 1.3e-29 102.9 19.3 1.3e-28 99.8 6.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EMD01042.1 - 0.0041 15.2 0.0 0.01 13.9 0.0 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family HIT PF01230.18 EMD01043.1 - 2.4e-15 56.8 0.1 9.4e-15 54.9 0.0 1.9 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EMD01043.1 - 0.012 15.7 0.1 0.11 12.6 0.1 2.1 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Rep_fac-A_3 PF08661.6 EMD01044.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Replication factor A protein 3 ZZ PF00569.12 EMD01045.1 - 0.0016 17.9 2.7 0.0033 16.9 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF4591 PF15261.1 EMD01045.1 - 0.011 15.9 3.0 0.016 15.4 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4591) DUF2989 PF11207.3 EMD01045.1 - 0.058 12.8 1.4 0.098 12.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Prok-RING_1 PF14446.1 EMD01045.1 - 0.15 11.7 6.5 0.36 10.5 4.5 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 MFS_1 PF07690.11 EMD01046.1 - 7.1e-15 54.5 39.6 3.1e-14 52.4 27.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2811 PF10929.3 EMD01046.1 - 0.069 13.1 0.9 0.18 11.8 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2811) DUF373 PF04123.8 EMD01046.1 - 0.094 11.7 1.6 0.18 10.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) 2H-phosphodiest PF08975.5 EMD01047.1 - 9.7e-25 86.6 0.0 1.4e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) 2_5_RNA_ligase2 PF13563.1 EMD01047.1 - 8.8e-05 22.2 0.0 0.00049 19.8 0.0 1.8 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily F-box PF00646.28 EMD01048.1 - 0.027 14.1 0.0 0.06 13.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain zf-C2H2 PF00096.21 EMD01050.1 - 1e-15 57.0 22.6 2e-05 24.6 0.1 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD01050.1 - 1.1e-15 57.0 20.6 1.5e-06 28.1 0.2 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD01050.1 - 2.7e-13 49.2 20.1 0.00029 20.9 0.1 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD01050.1 - 4.1e-08 33.1 18.1 0.0039 17.2 0.0 4.4 3 2 1 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMD01050.1 - 7.9e-06 25.8 15.3 0.00083 19.4 2.3 2.7 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMD01050.1 - 4.9e-05 23.0 8.4 0.012 15.4 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMD01050.1 - 0.0015 18.1 1.4 1.5 8.5 0.0 3.6 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-met PF12874.2 EMD01050.1 - 0.0016 18.5 4.1 0.045 13.9 0.3 4.0 3 1 0 4 4 3 2 Zinc-finger of C2H2 type XPA_N PF01286.13 EMD01050.1 - 0.0037 16.9 6.5 0.0068 16.0 0.1 2.7 3 0 0 3 3 3 1 XPA protein N-terminal FdhE PF04216.7 EMD01050.1 - 0.0054 16.4 0.2 0.0069 16.1 0.2 1.1 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation zf-C2H2_2 PF12756.2 EMD01050.1 - 0.013 15.6 9.5 0.07 13.2 0.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.7 EMD01050.1 - 0.013 15.6 8.8 0.038 14.1 6.0 1.9 1 1 1 2 2 2 0 CHY zinc finger DUF2180 PF09947.4 EMD01050.1 - 0.038 13.7 1.6 0.13 12.0 1.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Vps39_2 PF10367.4 EMD01050.1 - 0.057 13.5 2.2 0.94 9.6 0.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 TerY-C PF15616.1 EMD01050.1 - 0.2 11.6 3.7 0.23 11.3 2.6 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain DUF2256 PF10013.4 EMD01050.1 - 0.39 10.5 4.2 1.2 8.9 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_4 PF07975.7 EMD01050.1 - 0.63 10.0 5.0 18 5.4 0.0 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain zf-RING_3 PF14369.1 EMD01050.1 - 0.84 9.6 0.1 0.84 9.6 0.0 3.4 4 0 0 4 4 3 0 zinc-finger IBR PF01485.16 EMD01050.1 - 0.93 9.4 8.6 0.62 9.9 4.1 2.1 1 1 0 1 1 1 0 IBR domain Rad50_zn_hook PF04423.9 EMD01050.1 - 1.1 8.7 4.6 0.65 9.5 0.2 2.7 3 1 1 4 4 4 0 Rad50 zinc hook motif ADK_lid PF05191.9 EMD01050.1 - 1.3 8.7 4.8 25 4.6 3.4 2.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-piccolo PF05715.8 EMD01050.1 - 6 6.9 7.9 0.18 11.8 0.7 2.0 2 1 1 3 3 3 0 Piccolo Zn-finger zf-LITAF-like PF10601.4 EMD01050.1 - 9.4 6.1 8.7 2.1 8.2 0.4 2.9 1 1 1 3 3 3 0 LITAF-like zinc ribbon domain HMG_box PF00505.14 EMD01052.1 - 4.1e-08 33.3 12.4 5.2e-05 23.4 1.1 3.9 2 2 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EMD01052.1 - 9.7e-07 29.0 19.1 0.00048 20.4 1.9 3.7 3 1 0 3 3 3 2 HMG-box domain DUF1413 PF07205.6 EMD01052.1 - 0.035 13.6 0.3 0.1 12.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) DUF3138 PF11336.3 EMD01052.1 - 0.3 9.2 2.5 0.42 8.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CPSF100_C PF13299.1 EMD01052.1 - 1.6 8.9 5.4 3.6 7.7 3.8 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal UPF0020 PF01170.13 EMD01053.1 - 1.3e-12 47.6 0.0 2.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EMD01053.1 - 3.5e-09 36.7 0.0 7.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 EMD01053.1 - 0.12 11.7 0.2 0.4 10.0 0.0 1.8 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase N6_Mtase PF02384.11 EMD01053.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase PAF-AH_p_II PF03403.8 EMD01054.1 - 1.8e-49 168.0 0.0 4.9e-24 84.3 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMD01054.1 - 2.5e-08 33.7 0.1 3.5e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD01054.1 - 1e-06 28.8 0.0 2.6e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMD01054.1 - 0.00087 18.2 0.0 0.0018 17.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMD01054.1 - 0.0024 16.7 0.0 0.0042 15.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 EMD01054.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase DUF2293 PF10056.4 EMD01055.1 - 4.4e-15 55.4 0.1 9.3e-15 54.3 0.1 1.5 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2293) p450 PF00067.17 EMD01057.1 - 2e-62 211.2 0.0 2.6e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 EMD01060.1 - 5.6e-104 348.0 0.0 6.9e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 2-oxoacid_dh PF00198.18 EMD01061.1 - 1.2e-69 234.1 0.1 2e-69 233.4 0.0 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMD01061.1 - 4.7e-19 67.7 0.1 3.3e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EMD01061.1 - 2.4e-13 49.4 0.2 4.6e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain XRCC4 PF06632.7 EMD01061.1 - 0.068 12.0 1.4 0.1 11.4 1.0 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Vps26 PF03643.10 EMD01062.1 - 7.2e-120 398.8 0.0 8.7e-120 398.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EMD01062.1 - 0.0032 17.2 0.2 0.16 11.7 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF3500 PF12006.3 EMD01063.1 - 4.3e-83 278.8 0.0 5.1e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) adh_short_C2 PF13561.1 EMD01064.1 - 6.2e-29 101.4 0.2 7.8e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD01064.1 - 2.4e-24 86.1 1.4 2.9e-24 85.8 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD01064.1 - 1.9e-11 43.9 0.5 2.7e-11 43.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD01064.1 - 0.0019 17.6 2.4 0.0088 15.5 1.7 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family S4 PF01479.20 EMD01064.1 - 0.084 12.3 0.0 0.25 10.7 0.0 1.9 1 0 0 1 1 1 0 S4 domain Eno-Rase_NADH_b PF12242.3 EMD01064.1 - 0.088 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMD01064.1 - 0.12 12.3 1.8 0.34 10.8 1.2 1.8 1 1 0 1 1 1 0 NADH(P)-binding MOZART1 PF12554.3 EMD01066.1 - 1.2e-26 91.8 0.3 1.4e-26 91.6 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 EMD01066.1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 EMD01066.1 - 0.021 14.8 0.1 0.049 13.7 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain WXG100 PF06013.7 EMD01066.1 - 0.084 12.8 0.0 4.2 7.4 0.0 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Gryzun PF07919.7 EMD01067.1 - 5.3e-64 216.4 0.0 8e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EMD01067.1 - 1.7e-55 188.1 6.6 5.9e-53 179.8 3.1 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Ank_2 PF12796.2 EMD01068.1 - 1.1e-38 131.4 8.1 3.9e-17 62.3 0.1 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD01068.1 - 3.3e-28 97.0 6.0 1.1e-08 35.0 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EMD01068.1 - 2.1e-22 77.7 3.6 0.0001 21.9 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EMD01068.1 - 3.9e-21 74.9 2.0 1.9e-09 37.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD01068.1 - 1.3e-16 58.9 1.0 0.0068 16.5 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Shal-type PF11601.3 EMD01068.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels Sulfate_transp PF00916.15 EMD01070.1 - 4e-38 131.0 8.4 4e-38 131.0 5.8 1.6 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EMD01070.1 - 4.4e-16 58.4 0.0 8.2e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EMD01070.1 - 4.9e-10 38.8 0.0 9.4e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain PH_6 PF15406.1 EMD01071.1 - 6.1e-27 93.9 0.1 1.3e-26 92.8 0.0 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EMD01071.1 - 0.00044 20.4 0.0 0.00089 19.4 0.0 1.5 1 0 0 1 1 1 1 PH domain ubiquitin PF00240.18 EMD01073.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMD01073.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMD01073.1 - 0.04 14.1 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMD01073.1 - 0.12 12.3 0.0 0.32 10.8 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like S-methyl_trans PF02574.11 EMD01074.1 - 1.2e-74 251.3 0.0 1.4e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase AP_endonuc_2 PF01261.19 EMD01074.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Complex1_LYR_1 PF13232.1 EMD01075.1 - 6.1e-09 35.9 0.9 1.4e-08 34.8 0.6 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMD01075.1 - 1.2e-08 34.5 1.0 3.8e-08 32.9 0.7 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RPA_interact_M PF14767.1 EMD01075.1 - 0.16 12.7 1.4 0.38 11.5 1.0 1.7 1 0 0 1 1 1 0 Replication protein A interacting middle JAB PF01398.16 EMD01076.1 - 3.1e-08 33.3 0.0 9.2e-07 28.5 0.0 2.6 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GST_N_3 PF13417.1 EMD01077.1 - 2.1e-24 85.5 0.0 3.9e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD01077.1 - 1e-14 54.2 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD01077.1 - 3.2e-07 30.4 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD01077.1 - 1e-06 28.5 0.1 1.7e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD01077.1 - 0.0027 18.1 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD01077.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EMD01077.1 - 0.081 12.9 0.0 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin zf-C2H2 PF00096.21 EMD01079.1 - 1.5e-06 28.2 8.8 6e-05 23.1 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD01079.1 - 0.00013 22.1 2.1 0.00013 22.1 1.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD01079.1 - 0.00098 19.2 1.5 0.00098 19.2 1.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-RING_3 PF14369.1 EMD01079.1 - 0.1 12.6 0.5 0.31 11.0 0.4 1.8 1 0 0 1 1 1 0 zinc-finger Rtf2 PF04641.7 EMD01079.1 - 0.16 11.1 6.2 0.26 10.4 4.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger IU_nuc_hydro PF01156.14 EMD01080.1 - 7.7e-50 169.8 0.0 1.8e-39 135.7 0.0 2.2 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Methyltransf_31 PF13847.1 EMD01081.1 - 2.2e-08 33.7 0.0 1.4e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD01081.1 - 5.3e-08 32.7 0.0 6.9e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD01081.1 - 1.8e-06 28.3 0.0 5.1e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD01081.1 - 4.6e-06 27.0 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD01081.1 - 0.00084 19.9 0.0 0.008 16.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD01081.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family START PF01852.14 EMD01081.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 START domain Methyltransf_25 PF13649.1 EMD01081.1 - 0.03 14.6 0.0 0.26 11.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EMD01081.1 - 0.082 12.9 0.0 0.29 11.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF1903 PF08991.5 EMD01082.1 - 8.7e-24 83.4 10.3 9.9e-24 83.2 7.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EMD01082.1 - 0.028 14.3 9.3 0.028 14.3 6.5 1.7 2 0 0 2 2 2 0 CHCH domain Brr6_like_C_C PF10104.4 EMD01082.1 - 0.9 9.0 4.4 0.9 9.0 3.1 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Ligase_CoA PF00549.14 EMD01083.1 - 1e-33 116.1 4.2 7e-17 61.4 0.5 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EMD01083.1 - 1.3e-14 54.4 1.5 5e-14 52.5 0.0 2.5 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EMD01083.1 - 3.1e-10 39.8 1.3 8.2e-08 31.9 0.0 2.8 3 0 0 3 3 3 2 Succinyl-CoA ligase like flavodoxin domain DUF2856 PF11043.3 EMD01084.1 - 0.021 14.9 2.5 0.61 10.2 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) DUF605 PF04652.11 EMD01084.1 - 3.9 6.7 18.3 4.6 6.5 12.7 1.0 1 0 0 1 1 1 0 Vta1 like DUF2956 PF11169.3 EMD01084.1 - 7 6.6 11.8 7.4 6.5 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) AAA_2 PF07724.9 EMD01086.1 - 6.5e-48 162.8 0.0 1.2e-46 158.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EMD01086.1 - 2.9e-26 91.1 0.1 9.6e-26 89.5 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EMD01086.1 - 1.4e-20 73.8 0.1 3.7e-11 43.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD01086.1 - 2.2e-12 46.8 0.8 2.2e-08 33.9 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMD01086.1 - 4.4e-11 43.0 11.5 0.00014 21.9 0.0 5.3 4 2 2 6 6 6 3 AAA ATPase domain AAA_22 PF13401.1 EMD01086.1 - 2.2e-10 40.7 0.2 0.00048 20.2 0.0 3.5 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.1 EMD01086.1 - 7.6e-08 32.3 0.4 0.0072 16.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EMD01086.1 - 3.1e-07 30.0 0.6 6.6e-05 22.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 EMD01086.1 - 6.2e-06 25.9 0.2 0.094 12.3 0.1 2.8 2 1 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 EMD01086.1 - 1.8e-05 25.0 0.2 0.11 12.7 0.1 3.0 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EMD01086.1 - 1.9e-05 24.4 8.9 0.0041 16.8 0.2 4.3 3 2 0 3 3 2 1 Archaeal ATPase AAA_28 PF13521.1 EMD01086.1 - 4.8e-05 23.3 0.5 0.063 13.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EMD01086.1 - 5.2e-05 22.9 0.0 0.019 14.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain TrwB_AAD_bind PF10412.4 EMD01086.1 - 7.5e-05 21.5 0.1 0.13 10.8 0.0 3.2 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 EMD01086.1 - 0.00012 21.3 0.1 0.79 8.8 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMD01086.1 - 0.00013 22.8 5.6 0.17 12.6 0.1 3.6 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EMD01086.1 - 0.00014 21.2 0.2 0.41 10.0 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein MobB PF03205.9 EMD01086.1 - 0.00016 21.3 0.0 0.11 12.1 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 EMD01086.1 - 0.00024 20.9 0.3 1.3 8.7 0.0 3.4 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit SRP54 PF00448.17 EMD01086.1 - 0.00046 19.6 0.1 0.05 13.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EMD01086.1 - 0.0015 18.6 0.1 0.77 9.9 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EMD01086.1 - 0.0021 17.4 0.2 3.3 7.0 0.1 3.1 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EMD01086.1 - 0.0026 18.0 2.4 0.77 10.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.1 EMD01086.1 - 0.0028 17.2 2.8 0.33 10.4 0.0 4.1 3 1 1 5 5 3 1 AAA domain DUF815 PF05673.8 EMD01086.1 - 0.0032 16.4 0.4 0.22 10.4 0.2 3.4 3 2 0 3 3 3 1 Protein of unknown function (DUF815) DUF853 PF05872.7 EMD01086.1 - 0.0055 15.1 0.2 0.015 13.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) PduV-EutP PF10662.4 EMD01086.1 - 0.015 14.7 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 EMD01086.1 - 0.016 14.4 0.1 1 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 EMD01086.1 - 0.016 15.0 0.0 4.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMD01086.1 - 0.018 14.6 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMD01086.1 - 0.023 14.1 0.3 1.6 8.0 0.1 3.1 2 2 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EMD01086.1 - 0.03 13.5 0.0 6.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EMD01086.1 - 0.046 13.2 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EMD01086.1 - 0.049 13.2 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EMD01086.1 - 0.059 12.9 0.0 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 EMD01086.1 - 0.082 13.4 1.1 2.5 8.6 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein AAA_15 PF13175.1 EMD01086.1 - 0.14 11.1 1.4 0.15 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain UvrD-helicase PF00580.16 EMD01086.1 - 0.18 11.0 3.0 0.61 9.3 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Seryl_tRNA_N PF02403.17 EMD01086.1 - 0.31 11.0 12.7 2 8.4 8.8 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 EMD01086.1 - 4.6 6.1 7.6 10 4.9 5.3 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EF1_GNE PF00736.14 EMD01087.1 - 2.9e-32 110.2 2.1 4.8e-32 109.5 1.5 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EMD01087.1 - 5.7e-07 29.5 11.4 1.3e-06 28.4 7.9 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 EMD01087.1 - 0.0064 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain bZIP_1 PF00170.16 EMD01089.1 - 3.2e-09 36.6 7.8 3.2e-09 36.6 5.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EMD01089.1 - 6.4e-08 32.2 11.0 6.4e-08 32.2 7.6 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD01089.1 - 0.00047 20.3 6.9 0.00081 19.6 4.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Lebercilin PF15619.1 EMD01089.1 - 0.0014 18.0 2.2 0.0019 17.6 1.6 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.1 EMD01089.1 - 0.017 14.3 1.7 0.022 13.9 1.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding M PF02370.11 EMD01089.1 - 0.046 14.0 0.8 1.9 9.1 0.1 2.5 1 1 1 2 2 2 0 M protein repeat IncA PF04156.9 EMD01089.1 - 0.098 12.2 2.5 0.13 11.8 1.7 1.1 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EMD01090.1 - 3.9e-41 140.9 47.1 6.2e-41 140.2 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD01090.1 - 7.1e-14 51.2 11.4 7.1e-14 51.2 7.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.13 EMD01091.1 - 2.2e-17 62.8 0.0 4.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD01091.1 - 1.4e-08 34.5 9.2 2.3e-08 33.8 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L6e PF01159.14 EMD01093.1 - 1.4e-34 118.5 0.0 1.7e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 EMD01094.1 - 1.3e-26 92.4 0.0 2.1e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor MutS_V PF00488.16 EMD01095.1 - 4.2e-56 189.9 0.1 6.1e-55 186.1 0.0 2.1 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMD01095.1 - 1.7e-25 90.0 0.3 2.9e-25 89.2 0.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EMD01095.1 - 0.022 14.9 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV MMgT PF10270.4 EMD01096.1 - 8.6e-27 93.6 0.0 1.1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter DUF3185 PF11381.3 EMD01096.1 - 0.09 12.5 1.7 6.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) IncA PF04156.9 EMD01096.1 - 1.3 8.5 3.0 9 5.8 0.2 2.0 2 0 0 2 2 2 0 IncA protein Lipoxygenase PF00305.14 EMD01099.1 - 4.4e-36 124.1 0.2 6e-36 123.6 0.1 1.1 1 0 0 1 1 1 1 Lipoxygenase CK_II_beta PF01214.13 EMD01100.1 - 2.2e-77 258.7 0.0 6.9e-77 257.1 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EMD01100.1 - 0.021 15.4 23.9 0.24 12.0 9.1 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.8 EMD01100.1 - 0.42 10.1 13.6 0.82 9.2 2.5 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2890 PF11081.3 EMD01100.1 - 2.2 8.3 15.4 0.63 10.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) BSP_II PF05432.6 EMD01100.1 - 3.5 6.8 19.8 0.37 10.0 0.7 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EMD01100.1 - 8.7 5.3 15.1 3.9 6.5 0.8 2.2 2 0 0 2 2 2 0 Myc amino-terminal region RRM_1 PF00076.17 EMD01102.1 - 7.9e-60 198.4 0.0 1.7e-18 66.0 0.0 5.7 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD01102.1 - 1.5e-37 127.3 0.0 1.4e-10 41.0 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD01102.1 - 5.6e-21 74.1 0.1 4.3e-07 29.6 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 EMD01102.1 - 0.0048 16.8 6.0 0.0048 16.8 4.2 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit NosL PF05573.7 EMD01102.1 - 0.01 15.5 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 NosL Smg4_UPF3 PF03467.10 EMD01102.1 - 0.024 14.6 0.0 0.78 9.7 0.0 3.0 3 0 0 3 3 3 0 Smg-4/UPF3 family CDC45 PF02724.9 EMD01102.1 - 2.2 6.1 7.2 4.4 5.2 5.0 1.5 1 0 0 1 1 1 0 CDC45-like protein Cyt-b5 PF00173.23 EMD01104.1 - 6.1e-11 41.9 0.0 7.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UQ_con PF00179.21 EMD01106.1 - 1.2e-15 57.2 0.0 2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Daxx PF03344.10 EMD01106.1 - 0.74 8.2 17.3 1.1 7.6 12.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EMD01106.1 - 1.6 7.3 22.1 2.4 6.7 15.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF605 PF04652.11 EMD01106.1 - 1.9 7.8 12.5 3 7.1 8.6 1.2 1 0 0 1 1 1 0 Vta1 like BUD22 PF09073.5 EMD01106.1 - 2.2 7.2 15.8 3.2 6.7 10.9 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.7 EMD01106.1 - 8.2 5.4 21.2 13 4.8 14.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Dor1 PF04124.7 EMD01107.1 - 1e-49 168.8 8.2 1.9e-35 121.9 5.9 2.1 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 EMD01107.1 - 0.24 11.2 2.3 0.27 11.0 0.5 1.9 2 0 0 2 2 2 0 Vps51/Vps67 zf-C2H2 PF00096.21 EMD01109.1 - 9.5e-12 44.5 11.0 0.00027 21.1 0.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD01109.1 - 9.5e-08 31.8 13.3 0.00045 20.3 0.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 EMD01109.1 - 0.002 18.1 6.2 0.012 15.6 0.3 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EMD01109.1 - 2.6 8.4 18.2 0.2 12.0 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 EMD01109.1 - 6.2 7.2 9.2 42 4.6 0.0 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain PSP1 PF04468.7 EMD01111.1 - 1.3e-27 95.6 0.4 2.3e-27 94.7 0.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF4149 PF13664.1 EMD01112.1 - 5.4e-24 84.1 0.7 5.4e-24 84.1 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Glyco_hydro_3 PF00933.16 EMD01113.1 - 2e-89 299.5 0.0 3e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD01113.1 - 6.7e-50 169.7 0.5 1.4e-49 168.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD01113.1 - 1.8e-12 46.9 0.0 4.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF605 PF04652.11 EMD01113.1 - 3.7 6.8 37.8 6.2 6.1 26.2 1.3 1 0 0 1 1 1 0 Vta1 like 2OG-FeII_Oxy_2 PF13532.1 EMD01114.1 - 1.1e-13 51.4 0.0 3.8e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMD01114.1 - 1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dynactin_p62 PF05502.8 EMD01115.1 - 1e-114 383.9 14.4 2.5e-114 382.7 10.0 1.6 1 1 0 1 1 1 1 Dynactin p62 family Cadherin_2 PF08266.7 EMD01117.1 - 0.074 12.6 2.2 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Cadherin-like TAF PF02969.12 EMD01117.1 - 0.16 11.9 0.5 68 3.5 0.0 3.9 3 1 0 4 4 4 0 TATA box binding protein associated factor (TAF) Acetyltransf_9 PF13527.1 EMD01118.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_tranf_2_3 PF13641.1 EMD01119.1 - 5.7e-35 121.1 0.0 2.4e-34 119.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMD01119.1 - 2.5e-22 79.5 0.6 2.5e-22 79.5 0.4 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMD01119.1 - 5.7e-14 52.1 0.0 1.5e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMD01119.1 - 6.5e-13 48.3 0.0 1.1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EMD01119.1 - 6.6e-06 24.7 0.9 0.0006 18.2 0.0 2.4 2 1 0 2 2 2 2 Cellulose synthase Chitin_synth_2 PF03142.10 EMD01119.1 - 0.092 11.1 0.3 3.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Chitin synthase UAA PF08449.6 EMD01120.1 - 6.6e-10 38.3 3.7 4.7e-09 35.5 2.6 1.9 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EMD01120.1 - 4.5e-09 35.7 0.2 7e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EMD01120.1 - 2.2e-07 30.9 18.4 0.00039 20.4 3.2 2.8 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EMD01120.1 - 0.0037 16.9 16.3 0.16 11.6 4.4 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family O-antigen_lig PF13425.1 EMD01120.1 - 0.0042 17.0 1.7 0.0042 17.0 1.2 2.6 3 0 0 3 3 3 1 O-antigen ligase like membrane protein EmrE PF13536.1 EMD01120.1 - 0.0077 16.4 3.7 0.0077 16.4 2.6 3.3 3 2 0 3 3 3 1 Multidrug resistance efflux transporter F-box-like PF12937.2 EMD01121.1 - 0.16 11.7 8.7 0.6 9.8 4.4 2.6 1 1 1 2 2 2 0 F-box-like F-box PF00646.28 EMD01121.1 - 2.7 7.7 10.0 1.5 8.5 2.1 2.8 2 1 1 3 3 3 0 F-box domain Glyoxalase_3 PF13468.1 EMD01122.1 - 3.9e-24 85.4 0.0 4.9e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain IBR PF01485.16 EMD01123.1 - 1e-10 41.3 39.1 1.3e-06 28.1 1.6 3.8 3 1 0 3 3 3 3 IBR domain Fungal_trans PF04082.13 EMD01125.1 - 6.2e-29 100.6 0.0 1.3e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD01125.1 - 2.3e-11 43.4 12.6 3.9e-11 42.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EMD01126.1 - 1.1e-11 45.3 0.5 2.1e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 SET domain HrpB4 PF09502.5 EMD01126.1 - 0.076 12.1 0.3 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB4) DUF4451 PF14616.1 EMD01128.1 - 1.6e-06 27.8 6.7 0.0007 19.3 0.8 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4451) p450 PF00067.17 EMD01129.1 - 3.4e-66 223.6 0.0 5.2e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Med31 PF05669.7 EMD01130.1 - 3.5e-35 119.8 0.9 3.8e-35 119.7 0.6 1.0 1 0 0 1 1 1 1 SOH1 EF_assoc_1 PF08355.7 EMD01130.1 - 0.62 9.3 3.3 6.7 6.0 2.1 2.2 1 1 0 1 1 1 0 EF hand associated Pal1 PF08316.6 EMD01131.1 - 6e-42 143.4 1.5 6e-42 143.4 1.0 3.9 3 1 0 3 3 3 1 Pal1 cell morphology protein CDC45 PF02724.9 EMD01131.1 - 9.1 4.1 7.4 13 3.6 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIS_C PF01096.13 EMD01132.1 - 4e-18 64.7 9.5 3.7e-17 61.6 1.9 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMD01132.1 - 1.8e-05 24.3 12.4 0.0091 15.6 0.1 3.5 4 0 0 4 4 4 2 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EMD01132.1 - 0.037 13.8 7.7 0.33 10.7 0.9 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.3 EMD01132.1 - 0.04 13.3 0.1 0.12 11.7 0.1 1.9 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 EMD01132.1 - 0.056 13.2 0.9 0.056 13.2 0.7 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF951 PF06107.6 EMD01132.1 - 0.059 12.8 1.4 0.31 10.5 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF2387 PF09526.5 EMD01132.1 - 0.17 11.8 7.9 3 7.8 1.5 3.1 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Terminase_GpA PF05876.7 EMD01132.1 - 1.9 6.7 6.5 0.44 8.8 0.8 1.9 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-tcix PF14952.1 EMD01132.1 - 2.1 7.7 8.6 0.96 8.8 0.1 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding C1_4 PF07975.7 EMD01132.1 - 7.1 6.7 11.0 16 5.6 1.0 3.0 2 2 0 2 2 2 0 TFIIH C1-like domain zf-Mss51 PF13824.1 EMD01132.1 - 9.9 6.1 7.3 16 5.4 1.3 2.6 2 2 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ank_2 PF12796.2 EMD01133.1 - 5e-20 71.6 0.2 3.8e-11 43.1 0.0 1.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD01133.1 - 7.4e-12 44.4 0.0 0.0011 18.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMD01133.1 - 8.1e-12 45.3 0.0 2.9e-08 34.0 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD01133.1 - 3.5e-10 39.7 0.0 6.4e-05 23.0 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD01133.1 - 8.4e-10 37.9 0.0 0.022 14.9 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeat Herpes_gE PF02480.11 EMD01134.1 - 0.019 13.2 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2029 PF09594.5 EMD01134.1 - 0.038 13.5 0.1 0.077 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) SKG6 PF08693.5 EMD01134.1 - 0.048 12.9 0.0 0.048 12.9 0.0 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Arrestin_C PF02752.17 EMD01136.1 - 2.9e-09 37.1 0.0 7.8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain bZIP_1 PF00170.16 EMD01137.1 - 1e-05 25.4 7.6 1.8e-05 24.6 5.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD01137.1 - 0.0075 16.0 7.5 0.017 14.9 5.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper ABC_tran_2 PF12848.2 EMD01137.1 - 0.37 10.6 6.8 1.3 8.9 4.7 1.9 1 0 0 1 1 1 0 ABC transporter DUF4407 PF14362.1 EMD01137.1 - 0.88 8.4 9.0 0.11 11.4 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 EMD01138.1 - 2.5e-12 47.3 1.3 2.5e-12 47.3 0.9 4.8 4 1 1 5 5 5 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EMD01138.1 - 0.00053 20.4 6.4 0.00053 20.4 4.5 4.2 3 2 1 4 4 4 1 Hyaluronan / mRNA binding family DUF3602 PF12223.3 EMD01139.1 - 2.5e-11 43.8 14.1 1.3e-05 25.5 2.4 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Kri1_C PF12936.2 EMD01140.1 - 3.7e-26 90.9 0.3 3.7e-26 90.9 0.2 4.3 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 EMD01140.1 - 7.2e-26 90.4 16.5 7.2e-26 90.4 11.4 5.3 5 1 0 5 5 5 1 KRI1-like family DUF836 PF05768.9 EMD01141.1 - 4.4e-15 55.7 0.0 5.4e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EMD01141.1 - 4.7e-05 23.2 0.1 8.8e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EMD01141.1 - 0.022 14.9 0.1 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain HpcH_HpaI PF03328.9 EMD01142.1 - 3.9e-34 117.4 0.0 4.9e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EMD01142.1 - 0.073 12.2 0.1 11 5.1 0.0 2.9 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase GHMP_kinases_C PF08544.8 EMD01142.1 - 0.079 13.1 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 GHMP kinases C terminal MRJP PF03022.11 EMD01143.1 - 2.4e-20 72.9 0.1 3.4e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.16 EMD01143.1 - 1.2 9.2 5.9 2.6 8.1 0.0 4.0 4 0 0 4 4 4 0 NHL repeat Chitin_bind_3 PF03067.10 EMD01144.1 - 0.0021 18.3 0.0 0.0026 18.0 0.0 1.1 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 EMD01144.1 - 0.036 13.8 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 DEAD PF00270.24 EMD01145.1 - 9.8e-33 113.0 0.0 9.9e-32 109.7 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD01145.1 - 9.6e-17 60.6 0.0 2.3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EMD01145.1 - 3.8e-14 51.9 0.0 9.8e-14 50.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EMD01145.1 - 0.00037 20.3 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMD01145.1 - 0.0048 17.0 0.1 0.052 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD01145.1 - 0.0084 15.8 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain INCENP_ARK-bind PF03941.10 EMD01146.1 - 2.9e-15 55.8 0.5 9.9e-15 54.1 0.0 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region GRASP55_65 PF04495.9 EMD01147.1 - 1.7e-45 154.3 0.0 3.6e-43 146.8 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ PF00595.19 EMD01147.1 - 0.041 14.0 0.0 17 5.7 0.0 2.8 3 0 0 3 3 3 0 PDZ domain (Also known as DHR or GLGF) XFP_N PF09364.5 EMD01148.1 - 1.2e-173 577.0 0.0 1.8e-173 576.4 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EMD01148.1 - 3e-85 284.3 0.0 6.3e-85 283.2 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EMD01148.1 - 5.6e-82 274.0 0.0 8.6e-82 273.4 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EMD01148.1 - 0.062 12.8 0.1 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Isochorismatase PF00857.15 EMD01149.1 - 1.1e-33 116.6 0.0 1.3e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Ipi1_N PF12333.3 EMD01150.1 - 0.06 13.3 0.4 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Sulfotransfer_3 PF13469.1 EMD01152.1 - 0.0002 22.2 2.4 0.00029 21.8 1.4 1.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EMD01152.1 - 0.058 12.6 0.0 0.085 12.1 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain MpPF1 PF07668.6 EMD01155.1 - 0.0076 15.4 1.0 0.0076 15.4 0.7 1.9 1 1 1 2 2 2 1 M penetrans paralogue family 1 ChaB PF06150.7 EMD01155.1 - 0.082 12.7 0.2 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 ChaB Fungal_trans PF04082.13 EMD01155.1 - 0.15 10.9 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain NUDIX PF00293.23 EMD01156.1 - 4.1e-09 36.1 0.0 6.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain E1-E2_ATPase PF00122.15 EMD01157.1 - 6.3e-18 64.6 0.0 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMD01157.1 - 2.1e-14 54.4 0.0 5.6e-11 43.2 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD01157.1 - 5.5e-14 52.7 0.0 2.6e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD01157.1 - 1.5e-10 40.8 0.0 6.1e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMD01157.1 - 0.0019 17.8 0.0 0.0077 15.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IncA PF04156.9 EMD01158.1 - 9.1e-05 22.1 58.7 0.0013 18.3 9.4 4.5 1 1 2 4 4 4 3 IncA protein TMF_DNA_bd PF12329.3 EMD01158.1 - 0.00086 19.0 4.9 0.00086 19.0 3.4 7.1 2 1 5 7 7 7 2 TATA element modulatory factor 1 DNA binding WEMBL PF05701.6 EMD01158.1 - 0.14 10.5 69.3 0.27 9.6 19.2 3.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 EMD01158.1 - 0.4 9.8 12.4 0.63 9.1 2.1 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 EMD01158.1 - 0.52 9.7 60.4 15 4.9 39.9 3.6 1 1 1 2 2 2 0 Intermediate filament protein MscS_porin PF12795.2 EMD01158.1 - 1.1 8.4 59.9 1.7 7.9 8.0 3.7 1 1 4 5 5 5 0 Mechanosensitive ion channel porin domain Nup54 PF13874.1 EMD01158.1 - 1.9 8.1 51.1 0.055 13.1 6.4 4.6 1 1 4 5 5 5 0 Nucleoporin complex subunit 54 PHD PF00628.24 EMD01160.1 - 2.1e-12 46.5 6.0 5.6e-12 45.1 4.1 1.8 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 EMD01160.1 - 0.0019 17.7 2.2 0.64 9.4 0.2 2.4 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain Steroid_dh PF02544.11 EMD01161.1 - 2.6e-10 40.2 1.2 2.9e-10 40.0 0.1 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EMD01161.1 - 0.013 14.8 0.6 0.013 14.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) NmrA PF05368.8 EMD01162.1 - 2.4e-11 43.3 0.0 3.5e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD01162.1 - 7.5e-09 35.8 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD01162.1 - 3.3e-05 23.4 0.0 0.00021 20.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMD01162.1 - 0.0021 17.0 0.0 0.0079 15.1 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMD01162.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase COBRA PF04833.10 EMD01163.1 - 0.063 13.0 0.2 0.076 12.7 0.2 1.1 1 0 0 1 1 1 0 COBRA-like protein Ferric_reduct PF01794.14 EMD01164.1 - 1.2e-18 67.3 7.9 3.4e-18 65.9 5.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMD01164.1 - 1.6e-16 60.5 0.0 2.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD01164.1 - 1.2e-09 37.9 0.0 2.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMD01164.1 - 0.0066 17.0 0.0 0.76 10.3 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF2177 PF09945.4 EMD01164.1 - 0.028 14.4 1.0 0.028 14.4 0.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) Peptidase_M9_N PF08453.5 EMD01164.1 - 0.16 11.2 0.5 0.28 10.5 0.3 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal Stb3 PF10330.4 EMD01166.1 - 2.1e-30 104.2 0.0 4.3e-30 103.2 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein Uso1_p115_head PF04869.9 EMD01169.1 - 3.5e-49 167.2 0.0 7.5e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EMD01169.1 - 1.5e-06 28.1 26.4 1.5e-06 28.1 18.3 4.3 2 1 2 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Reo_sigmaC PF04582.7 EMD01169.1 - 0.00062 19.0 1.1 0.00062 19.0 0.7 2.9 2 1 1 3 3 3 1 Reovirus sigma C capsid protein Mt_ATP-synt_B PF05405.9 EMD01169.1 - 1.5 8.2 13.0 1.2 8.6 7.1 2.3 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATG16 PF08614.6 EMD01169.1 - 5.2 6.8 58.2 0.071 12.9 6.4 4.5 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Amino_oxidase PF01593.19 EMD01170.1 - 1.3e-66 225.6 0.6 1.1e-65 222.5 0.4 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMD01170.1 - 4.3e-15 55.4 0.2 9.2e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD01170.1 - 5.5e-07 28.8 0.3 0.022 13.6 0.3 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD01170.1 - 5.4e-05 23.3 0.3 0.1 12.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD01170.1 - 0.0019 17.9 0.9 0.011 15.5 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EMD01170.1 - 0.011 14.2 0.1 0.38 9.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EMD01170.1 - 0.037 13.9 0.3 0.41 10.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD01170.1 - 0.049 12.5 0.1 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein MFS_1 PF07690.11 EMD01171.1 - 4.6e-45 153.8 50.2 9e-44 149.6 35.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.16 EMD01171.1 - 0.11 11.3 18.3 0.38 9.4 8.6 2.2 2 0 0 2 2 2 0 POT family Mmp37 PF09139.6 EMD01173.1 - 6.6e-122 406.6 0.0 1.8e-121 405.2 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 BIR PF00653.16 EMD01174.1 - 1.1e-40 137.8 3.7 4.4e-21 75.0 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Tim54 PF11711.3 EMD01175.1 - 4.5e-123 410.6 0.2 5.1e-123 410.4 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 ADH_N PF08240.7 EMD01176.1 - 1.6e-25 88.9 0.7 3.4e-25 87.9 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD01176.1 - 3.5e-20 71.8 0.6 7.9e-20 70.7 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 EMD01178.1 - 7.4e-16 57.7 0.1 1.4e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD01178.1 - 2e-07 30.7 9.6 4.1e-07 29.7 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EMD01179.1 - 1.2e-06 28.3 9.0 1.2e-06 28.3 6.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD01179.1 - 7.3e-06 24.8 0.6 2.7e-05 22.9 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Yos1 PF08571.5 EMD01179.1 - 0.13 12.3 1.6 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Yos1-like Methyltransf_4 PF02390.12 EMD01180.1 - 8e-51 171.8 0.0 9.4e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EMD01180.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD01180.1 - 0.00017 21.9 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD01180.1 - 0.00026 21.0 0.0 0.00042 20.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD01180.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD01180.1 - 0.0032 18.0 0.0 0.0039 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD01180.1 - 0.0042 17.5 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD01180.1 - 0.0058 16.0 0.0 0.0086 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EMD01180.1 - 0.0096 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EMD01180.1 - 0.022 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Hira PF07569.6 EMD01181.1 - 3.4e-79 265.1 0.0 5.1e-79 264.5 0.0 1.3 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EMD01181.1 - 8.2e-44 145.9 15.0 5.6e-08 32.3 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EMD01181.1 - 2.3e-09 36.5 0.1 4.8e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 HIRA B motif IKI3 PF04762.7 EMD01181.1 - 0.0025 15.7 0.1 0.049 11.4 0.0 2.4 3 0 0 3 3 3 1 IKI3 family PD40 PF07676.7 EMD01181.1 - 0.019 14.6 0.1 25 4.6 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CAP_GLY PF01302.20 EMD01182.1 - 4.5e-18 64.7 0.1 8.3e-18 63.8 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EMD01182.1 - 5.6e-10 38.6 5.0 0.04 13.5 0.0 5.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD01182.1 - 6.8e-06 25.7 4.0 0.095 12.4 0.3 4.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_7 PF13504.1 EMD01182.1 - 0.00011 21.8 3.8 34 5.2 0.1 6.8 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EMD01182.1 - 0.0027 17.5 9.0 14 6.1 0.1 6.1 5 2 1 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 EMD01182.1 - 0.011 15.7 5.4 44 4.5 0.0 6.3 7 0 0 7 7 7 0 Leucine Rich repeat CBFD_NFYB_HMF PF00808.18 EMD01184.1 - 1.1e-09 38.1 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMD01184.1 - 0.00023 21.2 0.0 0.00036 20.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF792 PF05632.6 EMD01184.1 - 0.0081 15.5 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF792) SPX PF03105.14 EMD01184.1 - 0.0083 15.9 1.5 0.01 15.6 1.0 1.2 1 0 0 1 1 1 1 SPX domain SAPS PF04499.10 EMD01184.1 - 2.9 6.4 4.7 3.7 6.0 3.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CRC_subunit PF08624.5 EMD01185.1 - 8.2e-54 181.2 0.2 1.4e-53 180.5 0.0 1.5 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.14 EMD01186.1 - 1.4e-94 317.0 0.2 2.3e-94 316.3 0.1 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EMD01186.1 - 2.2e-09 37.5 6.3 6.2e-09 36.0 0.0 3.7 3 1 1 4 4 4 1 PIN domain Zn_clus PF00172.13 EMD01187.1 - 0.015 15.2 5.1 0.015 15.2 3.6 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.14 EMD01187.1 - 0.46 10.1 2.9 11 5.7 0.7 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Fungal_trans PF04082.13 EMD01188.1 - 3.1e-05 23.0 0.1 5.4e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD01188.1 - 1.6 8.6 10.5 3.2 7.7 7.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_11 PF08279.7 EMD01189.1 - 0.018 14.6 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 0 HTH domain Pyr_redox_3 PF13738.1 EMD01190.1 - 7.9e-26 91.3 0.0 1e-24 87.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD01190.1 - 3.6e-15 55.1 0.0 1.8e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMD01190.1 - 4.3e-10 39.4 0.0 1.7e-09 37.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD01190.1 - 1.6e-06 28.1 0.0 2.1e-05 24.4 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD01190.1 - 5.4e-06 25.5 0.0 0.0018 17.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMD01190.1 - 2.7e-05 23.9 0.5 0.0016 18.2 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMD01190.1 - 0.0024 18.2 0.1 0.15 12.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD01190.1 - 0.014 14.3 0.5 1.1 8.0 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMD01190.1 - 0.028 13.5 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 EMD01190.1 - 0.039 13.0 0.2 4.8 6.1 0.0 2.8 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.9 EMD01190.1 - 0.94 7.8 1.9 0.65 8.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_6 PF12697.2 EMD01191.1 - 2e-21 76.9 0.1 1.2e-20 74.3 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD01191.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD01191.1 - 0.018 14.5 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.9 EMD01191.1 - 0.058 11.8 0.0 0.091 11.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Tocopherol_cycl PF14249.1 EMD01192.1 - 0.0026 16.5 0.1 0.0062 15.2 0.1 1.7 2 0 0 2 2 2 1 Tocopherol cyclase TT_ORF2 PF02957.10 EMD01193.1 - 0.035 14.7 1.4 0.035 14.7 1.0 3.7 1 1 2 4 4 4 0 TT viral ORF2 RNase_PH PF01138.16 EMD01195.1 - 5e-15 55.9 0.0 8.6e-14 51.9 0.0 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Voltage_CLC PF00654.15 EMD01197.1 - 4.9e-88 295.5 20.0 6e-88 295.2 12.9 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EMD01197.1 - 0.00022 20.9 0.1 0.00041 20.0 0.1 1.5 1 0 0 1 1 1 1 CBS domain Choline_kinase PF01633.15 EMD01199.1 - 1.2e-51 175.2 0.0 1.7e-50 171.5 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EMD01199.1 - 4e-12 46.3 0.0 7.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMD01199.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase UQ_con PF00179.21 EMD01200.1 - 1.7e-30 105.2 0.0 2.8e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD01200.1 - 0.038 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B PI-PLC-X PF00388.14 EMD01201.1 - 1.2e-13 50.6 0.0 2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Pkinase PF00069.20 EMD01202.1 - 1.6e-55 188.0 0.0 2.4e-39 135.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD01202.1 - 6.9e-25 87.5 0.2 4.2e-20 71.9 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMD01202.1 - 9.5e-05 21.4 0.0 0.00021 20.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD01202.1 - 0.00011 22.0 0.2 0.026 14.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMD01202.1 - 0.00092 18.3 0.0 0.0031 16.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EMD01202.1 - 0.016 15.7 0.2 0.039 14.4 0.1 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain RIO1 PF01163.17 EMD01202.1 - 0.018 14.3 1.8 0.033 13.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 EMD01202.1 - 0.066 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3584 PF12128.3 EMD01203.1 - 1.5e-06 25.9 30.5 1.5e-06 25.9 21.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) Filament PF00038.16 EMD01203.1 - 0.0016 17.9 11.6 0.0016 17.9 8.1 5.1 4 1 0 4 4 4 2 Intermediate filament protein Aldo_ket_red PF00248.16 EMD01204.1 - 2.9e-57 193.6 0.0 3.4e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EMD01205.1 - 3.4e-25 88.4 48.6 1.3e-13 50.3 17.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD01205.1 - 0.00028 19.4 16.9 0.00028 19.4 11.7 2.4 1 1 2 3 3 3 2 MFS/sugar transport protein Fe_hyd_lg_C PF02906.9 EMD01206.1 - 1.5e-62 211.4 0.0 2.7e-62 210.6 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Ribosomal_L10 PF00466.15 EMD01207.1 - 0.003 17.4 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 Glycos_transf_3 PF00591.16 EMD01208.1 - 1.3e-56 191.8 0.0 2.5e-56 190.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EMD01208.1 - 8.5e-08 31.6 0.1 2e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Acetyltransf_1 PF00583.19 EMD01209.1 - 2.6e-07 30.5 0.1 3.6e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD01209.1 - 1.1e-06 28.7 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD01209.1 - 0.0001 22.1 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD01209.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMD01209.1 - 0.016 15.3 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BAALC_N PF06989.7 EMD01210.1 - 0.23 11.8 1.3 0.8 10.0 0.9 2.0 1 1 0 1 1 1 0 BAALC N-terminus FAD_binding_3 PF01494.14 EMD01211.1 - 3.6e-10 39.4 0.1 1e-09 37.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD01211.1 - 0.0042 16.0 0.1 0.46 9.3 0.1 2.7 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD01211.1 - 0.016 15.2 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Mito_fiss_reg PF05308.6 EMD01213.1 - 0.15 11.4 9.4 0.16 11.2 6.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator FAP PF07174.6 EMD01213.1 - 2.4 7.3 12.4 2.4 7.3 8.6 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ESSS PF10183.4 EMD01214.1 - 1.2e-27 96.3 0.0 1.3e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2293 PF10056.4 EMD01215.1 - 2.4e-13 49.8 0.0 6.6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) SNF5 PF04855.7 EMD01216.1 - 9.6e-70 234.8 0.0 1.4e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EMD01216.1 - 0.00044 19.5 4.1 0.0013 18.0 2.9 1.9 1 1 0 1 1 1 1 GATA zinc finger Terminase_GpA PF05876.7 EMD01216.1 - 0.11 10.7 1.0 0.14 10.4 0.0 1.5 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) WD40 PF00400.27 EMD01217.1 - 3.5e-51 169.3 15.7 7.8e-09 35.0 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMD01217.1 - 3.8e-05 22.0 2.9 0.03 12.4 0.1 3.5 1 1 1 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMD01217.1 - 0.0086 15.5 0.6 0.89 8.9 0.4 2.8 1 1 0 1 1 1 1 PQQ-like domain UreE_N PF02814.10 EMD01218.1 - 0.021 14.3 0.2 1.4 8.4 0.2 2.2 1 1 1 2 2 2 0 UreE urease accessory protein, N-terminal domain BTB PF00651.26 EMD01220.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain SPX PF03105.14 EMD01221.1 - 0.014 15.2 16.6 0.03 14.0 10.5 2.1 1 1 1 2 2 2 0 SPX domain PAT1 PF09770.4 EMD01221.1 - 0.94 7.6 28.6 1.2 7.2 19.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 EMD01221.1 - 1.5 7.9 31.4 2.6 7.1 21.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2278 PF10042.4 EMD01222.1 - 2.6e-56 190.6 0.1 4.8e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) DUF2547 PF10818.3 EMD01222.1 - 0.16 12.5 2.3 0.32 11.6 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) RNB PF00773.14 EMD01223.1 - 1.7e-83 280.6 0.0 3.9e-82 276.1 0.0 2.4 2 0 0 2 2 2 2 RNB domain FA_hydroxylase PF04116.8 EMD01225.1 - 3.1e-08 33.9 5.3 3.1e-08 33.9 3.7 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3425 PF11905.3 EMD01226.1 - 2e-18 66.6 0.0 5.1e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_6 PF12697.2 EMD01226.1 - 1.7e-13 50.9 10.7 1.5e-12 47.9 5.2 3.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD01226.1 - 4e-06 26.5 0.1 1.2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD01226.1 - 0.00012 21.8 0.0 0.0021 17.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF812 PF05667.6 EMD01226.1 - 0.23 9.9 11.5 0.021 13.3 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) NOA36 PF06524.7 EMD01226.1 - 1.7 7.8 4.3 2.9 7.0 3.0 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EMD01226.1 - 2 7.9 7.9 3.7 7.0 5.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EMD01226.1 - 5.1 7.4 10.4 12 6.2 7.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VPS9 PF02204.13 EMD01227.1 - 8.4e-30 102.8 0.0 1.6e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EMD01227.1 - 1.6e-11 43.4 0.1 7e-11 41.3 0.0 2.0 2 0 0 2 2 2 1 CUE domain DMA PF03474.9 EMD01227.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif G0-G1_switch_2 PF15103.1 EMD01227.1 - 1.1 9.4 3.5 1.4 9.1 0.4 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Sec7_N PF12783.2 EMD01228.1 - 3.9e-26 91.4 0.1 1.1e-24 86.7 0.0 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EMD01228.1 - 0.075 12.5 0.2 10 5.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Ribonuc_P_40 PF08584.6 EMD01229.1 - 4.8e-22 78.2 0.0 5.9e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit MFS_1 PF07690.11 EMD01230.1 - 1.7e-40 138.8 46.0 5.6e-40 137.1 31.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD01230.1 - 6e-06 25.0 13.9 6e-06 25.0 9.6 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter DUF1510 PF07423.6 EMD01230.1 - 0.012 15.0 0.9 0.02 14.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tom37_C PF11801.3 EMD01230.1 - 0.27 11.1 0.7 0.46 10.3 0.5 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain adh_short PF00106.20 EMD01231.1 - 1.2e-23 83.8 0.1 1.8e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD01231.1 - 8.7e-11 41.8 0.1 2.2e-10 40.4 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD01231.1 - 8.4e-07 28.9 0.2 5.3e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EMD01231.1 - 6.8e-05 22.5 0.2 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EMD01231.1 - 0.00023 20.7 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EMD01231.1 - 0.00031 19.8 0.0 0.00054 19.0 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EMD01231.1 - 0.00042 20.3 0.4 0.0013 18.8 0.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EMD01231.1 - 0.016 15.6 0.2 0.039 14.3 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EMD01231.1 - 0.058 13.6 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EMD01231.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EMD01231.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EMD01231.1 - 0.11 12.2 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cid2 PF09774.4 EMD01233.1 - 4.9e-47 159.8 0.0 5.7e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DUF4121 PF13497.1 EMD01233.1 - 0.077 11.9 0.0 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) DNA_ligase_A_M PF01068.16 EMD01234.1 - 2.7e-54 183.6 3.1 1.7e-43 148.3 0.1 2.8 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMD01234.1 - 1.3e-52 178.2 0.2 2e-52 177.5 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EMD01234.1 - 2.5e-28 98.3 0.3 3.4e-27 94.6 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Mito_carr PF00153.22 EMD01236.1 - 1.9e-56 187.7 6.1 2.7e-19 68.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 EMD01237.1 - 1.5e-19 69.9 47.4 3.6e-19 68.6 27.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox PF00070.22 EMD01238.1 - 2.4e-11 43.8 1.9 4.5e-11 43.0 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD01238.1 - 1.2e-06 28.5 4.8 1.4e-05 25.0 3.4 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD01238.1 - 0.037 12.9 0.0 0.11 11.4 0.0 1.7 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HAT PF02184.11 EMD01239.1 - 2.3e-21 75.2 67.8 1e-14 53.9 2.1 13.2 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EMD01239.1 - 8.7e-16 58.0 0.1 0.00087 19.5 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD01239.1 - 1.6e-12 47.7 11.1 0.015 15.9 0.0 7.4 7 1 3 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD01239.1 - 3.5e-12 45.7 15.4 0.027 15.0 0.0 10.5 5 2 8 13 13 12 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD01239.1 - 2.6e-09 36.2 12.0 0.27 11.2 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMD01239.1 - 7.2e-07 28.9 0.2 2.8 8.3 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD01239.1 - 1.1e-05 25.2 2.5 0.31 10.9 0.0 4.6 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 EMD01239.1 - 3e-05 23.5 1.6 1.4 8.6 0.0 5.2 4 2 1 5 5 5 2 TPR repeat TPR_15 PF13429.1 EMD01239.1 - 5.4e-05 22.3 10.1 0.021 13.9 1.7 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD01239.1 - 0.00078 19.0 3.0 9.4 6.2 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EMD01239.1 - 0.0044 16.7 18.9 0.045 13.5 0.6 6.9 5 2 4 9 9 9 1 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 EMD01239.1 - 0.0083 16.0 17.4 0.51 10.3 0.1 6.7 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMD01239.1 - 0.022 14.3 2.5 28 4.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMD01239.1 - 5.8 6.9 15.7 8.3 6.4 0.1 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Arf PF00025.16 EMD01241.1 - 6.2e-80 266.5 0.1 7.3e-80 266.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMD01241.1 - 4e-14 52.2 0.0 4.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMD01241.1 - 5.8e-13 48.5 0.0 6.3e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMD01241.1 - 2e-12 46.5 1.6 2.2e-09 36.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMD01241.1 - 4.6e-11 42.3 0.0 5.3e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMD01241.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMD01241.1 - 2.8e-06 27.2 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMD01241.1 - 0.0094 15.0 0.4 0.017 14.2 0.3 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EMD01241.1 - 0.013 14.9 0.1 0.11 11.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EMD01241.1 - 0.044 13.6 0.2 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain Leo1 PF04004.8 EMD01242.1 - 5.1e-26 91.4 0.3 1.2e-25 90.1 0.0 1.9 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 EMD01243.1 - 5.2e-31 107.6 0.3 8.6e-16 58.0 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family DUF4124 PF13511.1 EMD01243.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) DNA_pol_B_palm PF14792.1 EMD01244.1 - 3e-31 107.7 0.0 5.3e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EMD01244.1 - 4.6e-20 71.0 0.0 1.6e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 EMD01244.1 - 1.4e-18 66.8 0.2 3.8e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EMD01244.1 - 2.1e-17 62.3 0.1 4.6e-17 61.2 0.1 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 EMD01244.1 - 3.9e-06 27.1 0.0 8.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT PF00533.21 EMD01244.1 - 1.3e-05 25.2 0.0 6.1e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMD01244.1 - 0.056 13.3 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 twin BRCT domain KRAB PF01352.22 EMD01244.1 - 0.092 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 KRAB box Sld5 PF05916.6 EMD01245.1 - 1.1e-11 44.9 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 EMD01245.1 - 0.056 13.0 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Prefoldin_2 PF01920.15 EMD01247.1 - 1.8e-17 63.0 4.5 2.3e-17 62.6 3.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3584 PF12128.3 EMD01247.1 - 0.0076 13.6 2.5 0.0099 13.2 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) GvpG PF05120.7 EMD01247.1 - 0.011 15.4 0.8 0.033 13.9 0.0 1.9 2 1 0 2 2 2 0 Gas vesicle protein G BicD PF09730.4 EMD01247.1 - 0.044 12.1 6.3 0.21 9.9 0.4 2.0 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Uds1 PF15456.1 EMD01247.1 - 0.046 13.7 1.8 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Up-regulated During Septation 3H PF02829.9 EMD01247.1 - 0.048 13.6 0.3 0.093 12.7 0.2 1.5 1 1 0 1 1 1 0 3H domain BLOC1_2 PF10046.4 EMD01247.1 - 0.053 13.6 1.2 0.053 13.6 0.8 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin PF02996.12 EMD01247.1 - 0.06 12.9 0.5 0.06 12.9 0.4 2.1 2 0 0 2 2 2 0 Prefoldin subunit RasGAP_C PF03836.10 EMD01247.1 - 0.064 12.9 6.9 0.077 12.6 1.1 2.2 2 0 0 2 2 2 0 RasGAP C-terminus DUF4525 PF15027.1 EMD01247.1 - 0.073 12.6 0.2 0.09 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) YjcZ PF13990.1 EMD01247.1 - 0.12 11.5 2.1 0.21 10.6 0.1 1.9 2 0 0 2 2 2 0 YjcZ-like protein DUF1054 PF06335.7 EMD01247.1 - 0.13 11.9 0.8 0.22 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) Spc24 PF08286.6 EMD01247.1 - 0.16 11.7 7.1 0.19 11.4 0.8 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.1 EMD01247.1 - 0.93 9.4 5.1 0.46 10.4 0.5 2.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Val_tRNA-synt_C PF10458.4 EMD01247.1 - 0.97 9.5 4.0 0.87 9.7 0.4 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF1319 PF07028.6 EMD01247.1 - 1.1 9.5 5.1 3.3 7.9 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) EMP24_GP25L PF01105.19 EMD01247.1 - 1.4 8.5 4.3 3.1 7.4 0.1 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RmuC PF02646.11 EMD01247.1 - 1.6 7.5 7.9 0.43 9.3 0.4 2.0 2 0 0 2 2 2 0 RmuC family Fib_alpha PF08702.5 EMD01247.1 - 2 8.5 6.4 5.3 7.1 0.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 EMD01247.1 - 3.8 7.4 8.2 4.2 7.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Ceramidase PF05875.7 EMD01248.1 - 2.6e-100 334.9 7.5 3.5e-100 334.4 5.2 1.2 1 0 0 1 1 1 1 Ceramidase DUF4199 PF13858.1 EMD01248.1 - 3.8 7.4 8.1 3.1 7.6 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4199) Fungal_trans PF04082.13 EMD01250.1 - 8.1e-32 110.1 1.5 1.2e-31 109.5 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD01250.1 - 7e-05 22.6 15.5 0.00013 21.8 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bacillus_HBL PF05791.6 EMD01251.1 - 0.33 10.3 6.2 7.5 5.8 0.1 2.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Metallophos PF00149.23 EMD01252.1 - 2.6e-11 43.2 0.0 3.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD01252.1 - 1.2e-07 31.7 0.0 2.4e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 EMD01254.1 - 1.3e-60 204.7 0.0 1.9e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD01254.1 - 8.2e-32 110.2 0.0 3.3e-31 108.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMD01254.1 - 0.0027 16.5 0.0 0.0038 16.0 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase SIR2 PF02146.12 EMD01255.1 - 7.4e-59 198.4 0.0 1.1e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EMD01255.1 - 1.6e-06 27.7 0.0 4.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EMD01255.1 - 0.0045 16.7 0.0 4 7.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Apq12 PF12716.2 EMD01256.1 - 3.3e-11 42.6 9.1 5e-11 42.1 6.3 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis RNA_lig_T4_1 PF09511.5 EMD01257.1 - 1.6e-76 256.6 0.1 3.6e-76 255.5 0.0 1.6 2 0 0 2 2 2 1 RNA ligase tRNA_lig_CPD PF08302.6 EMD01257.1 - 2.6e-68 230.0 0.0 4e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EMD01257.1 - 2.6e-55 186.8 0.1 4.9e-55 185.9 0.1 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 EMD01257.1 - 0.0039 18.0 0.1 0.025 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EMD01257.1 - 0.068 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Rcd1 PF04078.8 EMD01259.1 - 4.2e-129 428.9 1.6 5.1e-129 428.7 1.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.8 EMD01259.1 - 0.69 9.7 14.7 0.83 9.4 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L1 PF00687.16 EMD01260.1 - 1.6e-52 178.0 0.9 1.9e-52 177.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WH2 PF02205.15 EMD01263.1 - 2.7e-09 36.3 0.6 2.4e-08 33.3 0.2 2.4 2 0 0 2 2 2 1 WH2 motif Rhomboid PF01694.17 EMD01265.1 - 4.3e-20 72.2 8.5 4.3e-20 72.2 5.9 1.5 2 0 0 2 2 2 1 Rhomboid family Peptidase_M50B PF13398.1 EMD01269.1 - 2.4e-55 187.0 18.5 3.1e-55 186.6 12.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EMD01269.1 - 0.027 13.4 0.3 0.027 13.4 0.2 2.5 2 1 1 3 3 3 0 Peptidase family M50 Epiglycanin_C PF14654.1 EMD01269.1 - 0.072 13.1 1.8 5.3 7.0 0.1 2.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region YlaC PF10777.4 EMD01269.1 - 0.15 11.6 0.3 0.34 10.4 0.2 1.6 1 0 0 1 1 1 0 Inner membrane protein YlaC Patched PF02460.13 EMD01269.1 - 1.4 6.7 4.9 2.5 5.9 3.4 1.3 1 0 0 1 1 1 0 Patched family p450 PF00067.17 EMD01271.1 - 2.5e-74 250.5 0.0 3.1e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LIM PF00412.17 EMD01272.1 - 5.6e-25 87.1 30.7 4.7e-09 36.1 3.8 4.1 4 0 0 4 4 4 3 LIM domain PITH PF06201.8 EMD01275.1 - 5.9e-48 162.4 0.0 7.2e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.8 EMD01275.1 - 0.054 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal BTB PF00651.26 EMD01277.1 - 5.6e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain DUF2850 PF11012.3 EMD01277.1 - 0.053 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) BTB PF00651.26 EMD01280.1 - 0.0028 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CUE PF02845.11 EMD01281.1 - 3.7e-09 35.8 0.0 6.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain HA2 PF04408.18 EMD01282.1 - 2.1e-21 75.8 0.2 3.7e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMD01282.1 - 7.2e-17 61.2 0.0 1.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMD01282.1 - 9.6e-12 44.6 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMD01282.1 - 8.6e-06 25.9 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EMD01282.1 - 3.9e-05 23.2 0.0 7.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EMD01282.1 - 0.0082 16.0 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EMD01282.1 - 0.013 14.9 0.0 0.053 12.9 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EMD01282.1 - 0.024 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMD01282.1 - 0.048 13.5 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMD01282.1 - 0.06 12.4 0.8 0.25 10.3 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_29 PF13555.1 EMD01282.1 - 0.061 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BTB PF00651.26 EMD01283.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EMD01284.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MA-Mit PF09245.5 EMD01286.1 - 0.15 11.3 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen Cupin_8 PF13621.1 EMD01287.1 - 1.7e-20 73.5 0.0 2.3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMD01287.1 - 0.026 13.7 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.6 EMD01287.1 - 0.15 11.6 0.0 0.51 9.8 0.0 1.8 2 0 0 2 2 2 0 Cupin domain ADH_N PF08240.7 EMD01288.1 - 1.7e-33 114.6 1.9 3.2e-33 113.7 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD01288.1 - 1.9e-14 53.2 0.0 3.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD01288.1 - 0.0042 17.9 0.0 0.0077 17.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EMD01288.1 - 0.024 13.7 0.1 0.038 13.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EMD01288.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EMD01288.1 - 0.13 12.0 0.1 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 ThiF family AMP-binding PF00501.23 EMD01289.1 - 8.5e-72 241.8 0.0 1e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD01289.1 - 5e-08 33.7 0.0 1.3e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HET PF06985.6 EMD01290.1 - 1.5e-13 51.0 1.2 1e-12 48.3 0.8 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CorA PF01544.13 EMD01291.1 - 1.1e-13 50.8 0.1 2e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Filament PF00038.16 EMD01291.1 - 0.03 13.7 3.5 0.056 12.8 2.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein Effector_1 PF04518.7 EMD01291.1 - 0.045 12.7 0.8 0.073 12.0 0.6 1.2 1 0 0 1 1 1 0 Effector from type III secretion system RXT2_N PF08595.6 EMD01292.1 - 8.1e-32 110.0 0.0 1.9e-31 108.8 0.0 1.7 1 0 0 1 1 1 1 RXT2-like, N-terminal FAP PF07174.6 EMD01292.1 - 0.23 10.7 8.0 0.39 9.9 5.6 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF605 PF04652.11 EMD01292.1 - 0.26 10.6 5.2 0.37 10.1 3.6 1.3 1 1 0 1 1 1 0 Vta1 like FAD_binding_3 PF01494.14 EMD01293.1 - 3.1e-08 33.0 0.4 0.00035 19.7 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 EMD01293.1 - 2e-07 30.2 0.1 0.00055 18.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD01293.1 - 0.00064 19.6 0.1 0.0052 16.6 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD01293.1 - 0.0012 17.7 0.3 0.0025 16.7 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EMD01293.1 - 0.0064 16.8 0.3 0.08 13.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD01293.1 - 0.0095 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMD01293.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMD01293.1 - 0.12 11.4 0.0 4.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase COesterase PF00135.23 EMD01294.1 - 2e-99 333.7 0.1 2.6e-99 333.3 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD01294.1 - 0.00025 20.6 0.4 0.0022 17.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD01294.1 - 0.017 14.3 0.1 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF834 PF05754.9 EMD01294.1 - 0.055 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF834) HET PF06985.6 EMD01295.1 - 2e-24 86.3 0.1 3.1e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APS_kinase PF01583.15 EMD01296.1 - 2.7e-72 241.5 0.0 3.3e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EMD01296.1 - 2.8e-06 28.1 0.0 5.1e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD01296.1 - 5.7e-06 26.2 0.0 8.8e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMD01296.1 - 4.7e-05 22.7 0.0 5.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EMD01296.1 - 0.00047 20.4 0.0 0.00084 19.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMD01296.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMD01296.1 - 0.05 13.5 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.12 EMD01296.1 - 0.076 12.3 0.1 2.8 7.2 0.0 2.2 1 1 1 2 2 2 0 Thymidylate kinase Ribosomal_S21 PF01165.15 EMD01297.1 - 0.1 12.0 1.0 0.18 11.2 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 GCV_T PF01571.16 EMD01298.1 - 1.8e-58 197.3 0.0 2.3e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EMD01298.1 - 1.9e-21 75.9 1.2 3.2e-21 75.1 0.8 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 EMD01298.1 - 0.0041 17.0 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus V-ATPase_C PF03223.10 EMD01299.1 - 5.8e-116 387.4 0.0 6.6e-116 387.2 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EMD01299.1 - 0.037 14.3 0.0 0.092 13.0 0.0 1.7 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Mod_r PF07200.8 EMD01299.1 - 0.11 12.4 2.7 0.77 9.6 0.0 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PhoD PF09423.5 EMD01300.1 - 9.7e-10 37.5 0.0 2.9e-07 29.4 0.0 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase DUF1913 PF08931.5 EMD01302.1 - 0.11 12.2 0.1 14 5.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1913) Acetyltransf_1 PF00583.19 EMD01303.1 - 7.2e-10 38.7 0.0 1.6e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMD01303.1 - 5.8e-06 25.9 0.0 1.3e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EMD01303.1 - 0.0016 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EMD01303.1 - 0.0016 18.5 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD01303.1 - 0.0019 18.2 0.5 0.0042 17.1 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD01303.1 - 0.01 16.0 0.0 0.021 14.9 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DAP10 PF07213.6 EMD01304.1 - 3.9e-06 26.5 0.1 9.2e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 DAP10 membrane protein EphA2_TM PF14575.1 EMD01304.1 - 0.035 14.5 0.0 0.1 13.0 0.0 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.6 EMD01304.1 - 0.041 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Podoplanin Rax2 PF12768.2 EMD01304.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.5 EMD01304.1 - 0.26 10.6 5.0 0.5 9.7 3.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 EMD01305.1 - 0.0034 17.5 1.0 0.074 13.2 0.0 2.7 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator SKG6 PF08693.5 EMD01305.1 - 0.0042 16.3 4.4 0.0042 16.3 3.1 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EMD01305.1 - 0.0097 15.4 0.3 0.03 13.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Syndecan PF01034.15 EMD01305.1 - 0.086 12.5 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain V-ATPase_H_N PF03224.9 EMD01306.1 - 5.6e-74 249.0 0.6 7.7e-74 248.6 0.2 1.4 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EMD01306.1 - 1.3e-35 121.9 0.1 4.2e-35 120.2 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H RIX1 PF08167.7 EMD01306.1 - 4.5 6.9 6.4 2.3 7.9 0.1 3.3 3 2 2 5 5 5 0 rRNA processing/ribosome biogenesis Sterol-sensing PF12349.3 EMD01307.1 - 3.7e-38 130.3 10.5 3.7e-38 130.3 7.3 2.5 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EMD01307.1 - 1.5e-16 59.5 6.5 2.6e-16 58.7 4.5 1.3 1 0 0 1 1 1 1 Patched family GN3L_Grn1 PF08701.6 EMD01311.1 - 5.5e-26 90.2 12.9 1.2e-25 89.2 8.9 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase DUF3367 PF11847.3 EMD01311.1 - 2.6 5.8 4.6 3.5 5.4 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Myb_DNA-bind_6 PF13921.1 EMD01312.1 - 4.2e-06 26.7 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMD01312.1 - 0.013 15.4 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain HTH_38 PF13936.1 EMD01312.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain EMP24_GP25L PF01105.19 EMD01314.1 - 3e-48 163.9 0.1 3.6e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AAA PF00004.24 EMD01315.1 - 2.3e-84 280.2 0.0 2.2e-41 141.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD01315.1 - 2e-10 40.5 0.1 4.8e-05 23.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD01315.1 - 2.7e-10 40.4 0.2 0.034 14.2 0.0 4.6 3 2 1 4 4 3 2 AAA domain AAA_2 PF07724.9 EMD01315.1 - 4e-10 39.8 0.0 0.0015 18.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMD01315.1 - 7.1e-10 39.1 3.9 0.0017 18.3 0.0 4.4 3 2 1 4 4 3 2 AAA ATPase domain RuvB_N PF05496.7 EMD01315.1 - 3.9e-08 32.6 0.0 0.0034 16.4 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMD01315.1 - 1e-07 32.7 0.0 0.00066 20.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMD01315.1 - 2.2e-07 30.1 0.0 0.0025 16.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EMD01315.1 - 5e-07 29.6 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMD01315.1 - 1.7e-06 27.9 0.0 0.071 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EMD01315.1 - 1.7e-06 27.6 0.1 0.11 12.2 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EMD01315.1 - 2.7e-06 26.6 1.1 0.055 12.6 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EMD01315.1 - 1.1e-05 24.9 3.6 0.84 9.0 0.2 4.3 2 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.12 EMD01315.1 - 1.6e-05 24.4 0.3 0.028 13.8 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EMD01315.1 - 2.3e-05 24.5 0.1 0.32 11.1 0.0 3.2 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EMD01315.1 - 0.00025 21.0 0.0 0.48 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EMD01315.1 - 0.00035 20.2 0.1 4.4 6.9 0.0 3.8 3 1 1 4 4 4 0 NACHT domain PhoH PF02562.11 EMD01315.1 - 0.00041 19.6 0.0 0.41 9.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein KaiC PF06745.8 EMD01315.1 - 0.00062 18.9 0.0 1 8.4 0.0 2.8 3 0 0 3 3 3 2 KaiC AAA_18 PF13238.1 EMD01315.1 - 0.00082 19.6 0.0 2.1 8.6 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EMD01315.1 - 0.00096 18.7 0.0 0.7 9.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EMD01315.1 - 0.0013 18.3 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 EMD01315.1 - 0.0029 17.0 0.0 1.5 8.2 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain TIP49 PF06068.8 EMD01315.1 - 0.0037 16.0 0.0 0.57 8.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus ABC_tran PF00005.22 EMD01315.1 - 0.0064 16.7 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 EMD01315.1 - 0.0068 16.1 0.1 9.8 5.7 0.0 3.5 2 2 1 4 4 4 0 Archaeal ATPase SKI PF01202.17 EMD01315.1 - 0.0072 16.2 0.0 5.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase DUF815 PF05673.8 EMD01315.1 - 0.0085 15.0 0.0 0.29 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 EMD01315.1 - 0.0099 14.6 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ResIII PF04851.10 EMD01315.1 - 0.013 15.3 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.11 EMD01315.1 - 0.027 13.2 0.0 3.3 6.4 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_11 PF13086.1 EMD01315.1 - 0.027 14.0 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EMD01315.1 - 0.031 14.3 0.0 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EMD01315.1 - 0.057 12.2 0.0 8.5 5.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EMD01315.1 - 0.14 11.7 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMD01315.1 - 0.22 11.1 0.0 26 4.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Snf7 PF03357.16 EMD01316.1 - 1.8e-36 125.1 5.2 2.4e-36 124.7 3.6 1.2 1 0 0 1 1 1 1 Snf7 Nup54 PF13874.1 EMD01316.1 - 0.74 9.4 12.0 3.1 7.4 3.1 2.5 3 0 0 3 3 3 0 Nucleoporin complex subunit 54